reg-snw-4781

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.202	2.81e-07	4.63e-02	3.51e-02

chia-screen-data-Fav-reg-snw-4781 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
AGPS	8540	23	-2.424	2.410	27	-	Yes	Yes
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
CLU	1191	1	-1.633	2.202	14	-	-	-
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
[ NFIB ]	4781	2	-1.505	2.307	40	TF	-	-
CLASP1	23332	10	-2.365	2.459	39	TF	Yes	-
NFIX	4784	1	-1.772	2.202	6	TF	-	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CLU	1191	NFIB	4781	pd	<	reg.ITFP.txt: no annot
NFIB	4781	NFIX	4784	pd	<>	reg.ITFP.txt: no annot
CLU	1191	CLASP1	23332	pd	<	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
NFIB	4781	AGPS	8540	pd	>	reg.ITFP.txt: no annot
AGPS	8540	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot

Related GO terms (170)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003723	RNA binding	8.15e-04	1.00e+00	3.890	3	22	247
GO:0016149	translation release factor activity, codon specific	8.19e-04	1.00e+00	10.253	1	1	1
GO:0031592	centrosomal corona	8.19e-04	1.00e+00	10.253	1	1	1
GO:0061518	microglial cell proliferation	8.19e-04	1.00e+00	10.253	1	1	1
GO:1902949	positive regulation of tau-protein kinase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:1902847	regulation of neuronal signal transduction	8.19e-04	1.00e+00	10.253	1	1	1
GO:0021740	principal sensory nucleus of trigeminal nerve development	8.19e-04	1.00e+00	10.253	1	1	1
GO:2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis	8.19e-04	1.00e+00	10.253	1	1	1
GO:0008609	alkylglycerone-phosphate synthase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0008079	translation termination factor activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0061141	lung ciliated cell differentiation	8.19e-04	1.00e+00	10.253	1	1	1
GO:0042583	chromaffin granule	8.19e-04	1.00e+00	10.253	1	1	1
GO:0031111	negative regulation of microtubule polymerization or depolymerization	1.64e-03	1.00e+00	9.253	1	1	2
GO:0030981	cortical microtubule cytoskeleton	1.64e-03	1.00e+00	9.253	1	1	2
GO:0003747	translation release factor activity	1.64e-03	1.00e+00	9.253	1	2	2
GO:2000791	negative regulation of mesenchymal cell proliferation involved in lung development	1.64e-03	1.00e+00	9.253	1	1	2
GO:0032286	central nervous system myelin maintenance	1.64e-03	1.00e+00	9.253	1	1	2
GO:0051294	establishment of spindle orientation	1.64e-03	1.00e+00	9.253	1	1	2
GO:1900221	regulation of beta-amyloid clearance	1.64e-03	1.00e+00	9.253	1	1	2
GO:1902998	positive regulation of neurofibrillary tangle assembly	1.64e-03	1.00e+00	9.253	1	1	2
GO:0008611	ether lipid biosynthetic process	1.64e-03	1.00e+00	9.253	1	1	2
GO:0030529	ribonucleoprotein complex	1.89e-03	1.00e+00	4.896	2	5	82
GO:0006366	transcription from RNA polymerase II promoter	2.07e-03	1.00e+00	3.425	3	23	341
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	2.46e-03	1.00e+00	8.668	1	1	3
GO:1902004	positive regulation of beta-amyloid formation	2.46e-03	1.00e+00	8.668	1	1	3
GO:0017038	protein import	2.46e-03	1.00e+00	8.668	1	1	3
GO:0051788	response to misfolded protein	2.46e-03	1.00e+00	8.668	1	1	3
GO:0032463	negative regulation of protein homooligomerization	2.46e-03	1.00e+00	8.668	1	1	3
GO:0006260	DNA replication	2.47e-03	1.00e+00	4.699	2	9	94
GO:0097452	GAIT complex	3.27e-03	1.00e+00	8.253	1	2	4
GO:0021960	anterior commissure morphogenesis	3.27e-03	1.00e+00	8.253	1	1	4
GO:0006449	regulation of translational termination	3.27e-03	1.00e+00	8.253	1	1	4
GO:0097418	neurofibrillary tangle	3.27e-03	1.00e+00	8.253	1	1	4
GO:0044300	cerebellar mossy fiber	3.27e-03	1.00e+00	8.253	1	1	4
GO:0060486	Clara cell differentiation	3.27e-03	1.00e+00	8.253	1	1	4
GO:0043515	kinetochore binding	3.27e-03	1.00e+00	8.253	1	2	4
GO:0004521	endoribonuclease activity	4.09e-03	1.00e+00	7.931	1	1	5
GO:0008610	lipid biosynthetic process	4.09e-03	1.00e+00	7.931	1	1	5
GO:0010458	exit from mitosis	4.09e-03	1.00e+00	7.931	1	2	5
GO:0006398	histone mRNA 3'-end processing	4.09e-03	1.00e+00	7.931	1	1	5
GO:0005828	kinetochore microtubule	4.09e-03	1.00e+00	7.931	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.09e-03	1.00e+00	7.931	1	2	5
GO:0060510	Type II pneumocyte differentiation	4.09e-03	1.00e+00	7.931	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0021680	cerebellar Purkinje cell layer development	4.09e-03	1.00e+00	7.931	1	1	5
GO:0031023	microtubule organizing center organization	4.09e-03	1.00e+00	7.931	1	1	5
GO:0000398	mRNA splicing, via spliceosome	4.53e-03	1.00e+00	4.253	2	15	128
GO:1902430	negative regulation of beta-amyloid formation	4.91e-03	1.00e+00	7.668	1	1	6
GO:0021707	cerebellar granule cell differentiation	4.91e-03	1.00e+00	7.668	1	1	6
GO:0071679	commissural neuron axon guidance	4.91e-03	1.00e+00	7.668	1	1	6
GO:0097440	apical dendrite	4.91e-03	1.00e+00	7.668	1	1	6
GO:0060509	Type I pneumocyte differentiation	4.91e-03	1.00e+00	7.668	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	4.91e-03	1.00e+00	7.668	1	2	6
GO:0008409	5'-3' exonuclease activity	5.72e-03	1.00e+00	7.446	1	2	7
GO:0048708	astrocyte differentiation	5.72e-03	1.00e+00	7.446	1	1	7
GO:1901216	positive regulation of neuron death	5.72e-03	1.00e+00	7.446	1	1	7
GO:1901214	regulation of neuron death	5.72e-03	1.00e+00	7.446	1	1	7
GO:0034366	spherical high-density lipoprotein particle	5.72e-03	1.00e+00	7.446	1	1	7
GO:0051787	misfolded protein binding	6.54e-03	1.00e+00	7.253	1	2	8
GO:0071949	FAD binding	6.54e-03	1.00e+00	7.253	1	1	8
GO:0034453	microtubule anchoring	7.35e-03	1.00e+00	7.083	1	1	9
GO:0006379	mRNA cleavage	7.35e-03	1.00e+00	7.083	1	2	9
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	7.35e-03	1.00e+00	7.083	1	2	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	7.35e-03	1.00e+00	7.083	1	3	9
GO:0001774	microglial cell activation	7.35e-03	1.00e+00	7.083	1	1	9
GO:0008380	RNA splicing	7.43e-03	1.00e+00	3.887	2	21	165
GO:0008143	poly(A) binding	8.17e-03	1.00e+00	6.931	1	2	10
GO:0001578	microtubule bundle formation	8.17e-03	1.00e+00	6.931	1	2	10
GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	8.17e-03	1.00e+00	6.931	1	1	10
GO:0051131	chaperone-mediated protein complex assembly	8.17e-03	1.00e+00	6.931	1	3	10
GO:0051010	microtubule plus-end binding	8.98e-03	1.00e+00	6.794	1	2	11
GO:0007026	negative regulation of microtubule depolymerization	8.98e-03	1.00e+00	6.794	1	2	11
GO:0007020	microtubule nucleation	8.98e-03	1.00e+00	6.794	1	1	11
GO:0006479	protein methylation	8.98e-03	1.00e+00	6.794	1	2	11
GO:0010001	glial cell differentiation	8.98e-03	1.00e+00	6.794	1	1	11
GO:0030902	hindbrain development	1.14e-02	1.00e+00	6.446	1	2	14
GO:0043691	reverse cholesterol transport	1.14e-02	1.00e+00	6.446	1	1	14
GO:0005782	peroxisomal matrix	1.30e-02	1.00e+00	6.253	1	1	16
GO:0043022	ribosome binding	1.38e-02	1.00e+00	6.166	1	2	17
GO:0006378	mRNA polyadenylation	1.47e-02	1.00e+00	6.083	1	3	18
GO:0001106	RNA polymerase II transcription corepressor activity	1.47e-02	1.00e+00	6.083	1	2	18
GO:0006956	complement activation	1.63e-02	1.00e+00	5.931	1	2	20
GO:0007163	establishment or maintenance of cell polarity	1.63e-02	1.00e+00	5.931	1	1	20
GO:0071346	cellular response to interferon-gamma	1.63e-02	1.00e+00	5.931	1	2	20
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	1.71e-02	1.00e+00	5.861	1	2	21
GO:0061077	chaperone-mediated protein folding	1.79e-02	1.00e+00	5.794	1	1	22
GO:0002062	chondrocyte differentiation	1.79e-02	1.00e+00	5.794	1	2	22
GO:0001836	release of cytochrome c from mitochondria	1.79e-02	1.00e+00	5.794	1	1	22
GO:0043392	negative regulation of DNA binding	1.87e-02	1.00e+00	5.730	1	1	23
GO:0005881	cytoplasmic microtubule	1.95e-02	1.00e+00	5.668	1	3	24
GO:0005876	spindle microtubule	1.95e-02	1.00e+00	5.668	1	4	24
GO:0006958	complement activation, classical pathway	2.19e-02	1.00e+00	5.499	1	3	27
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	2.27e-02	1.00e+00	5.446	1	1	28
GO:0005778	peroxisomal membrane	2.35e-02	1.00e+00	5.395	1	3	29
GO:0045429	positive regulation of nitric oxide biosynthetic process	2.35e-02	1.00e+00	5.395	1	1	29
GO:0032760	positive regulation of tumor necrosis factor production	2.59e-02	1.00e+00	5.253	1	1	32
GO:0017148	negative regulation of translation	2.67e-02	1.00e+00	5.209	1	5	33
GO:0000902	cell morphogenesis	2.83e-02	1.00e+00	5.124	1	5	35
GO:0031093	platelet alpha granule lumen	2.83e-02	1.00e+00	5.124	1	3	35
GO:0031966	mitochondrial membrane	2.83e-02	1.00e+00	5.124	1	1	35
GO:0031124	mRNA 3'-end processing	2.83e-02	1.00e+00	5.124	1	4	35
GO:0000226	microtubule cytoskeleton organization	2.91e-02	1.00e+00	5.083	1	1	36
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	3.07e-02	1.00e+00	5.005	1	4	38
GO:0006369	termination of RNA polymerase II transcription	3.07e-02	1.00e+00	5.005	1	5	38
GO:0006396	RNA processing	3.23e-02	1.00e+00	4.931	1	4	40
GO:0006406	mRNA export from nucleus	3.55e-02	1.00e+00	4.794	1	7	44
GO:0005783	endoplasmic reticulum	3.64e-02	1.00e+00	2.680	2	12	381
GO:0051301	cell division	3.95e-02	1.00e+00	4.639	1	2	49
GO:0097193	intrinsic apoptotic signaling pathway	3.95e-02	1.00e+00	4.639	1	1	49
GO:0005777	peroxisome	4.03e-02	1.00e+00	4.610	1	2	50
GO:0000776	kinetochore	4.42e-02	1.00e+00	4.472	1	8	55
GO:0000777	condensed chromosome kinetochore	4.58e-02	1.00e+00	4.421	1	6	57
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	4.66e-02	1.00e+00	4.395	1	3	58
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	4.73e-02	1.00e+00	4.371	1	1	59
GO:0071013	catalytic step 2 spliceosome	4.89e-02	1.00e+00	4.323	1	5	61
GO:0002576	platelet degranulation	4.97e-02	1.00e+00	4.299	1	3	62
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.05e-02	1.00e+00	2.421	2	29	456
GO:0006415	translational termination	5.05e-02	1.00e+00	4.276	1	2	63
GO:0050821	protein stabilization	5.13e-02	1.00e+00	4.253	1	3	64
GO:0006629	lipid metabolic process	5.20e-02	1.00e+00	4.231	1	2	65
GO:0001649	osteoblast differentiation	5.91e-02	1.00e+00	4.044	1	5	74
GO:0005938	cell cortex	6.14e-02	1.00e+00	3.987	1	6	77
GO:0072562	blood microparticle	6.45e-02	1.00e+00	3.914	1	4	81
GO:0016020	membrane	6.54e-02	1.00e+00	1.601	3	56	1207
GO:0003690	double-stranded DNA binding	6.60e-02	1.00e+00	3.878	1	6	83
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.68e-02	1.00e+00	3.861	1	5	84
GO:0010467	gene expression	6.73e-02	1.00e+00	2.190	2	49	535
GO:0044255	cellular lipid metabolic process	7.07e-02	1.00e+00	3.778	1	2	89
GO:0051092	positive regulation of NF-kappaB transcription factor activity	7.07e-02	1.00e+00	3.778	1	2	89
GO:0000086	G2/M transition of mitotic cell cycle	7.68e-02	1.00e+00	3.653	1	7	97
GO:0008017	microtubule binding	7.68e-02	1.00e+00	3.653	1	9	97
GO:0009615	response to virus	7.68e-02	1.00e+00	3.653	1	3	97
GO:0016887	ATPase activity	7.91e-02	1.00e+00	3.610	1	5	100
GO:0031012	extracellular matrix	8.44e-02	1.00e+00	3.512	1	4	107
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	9.33e-02	1.00e+00	1.922	2	29	644
GO:0005739	mitochondrion	9.71e-02	1.00e+00	1.889	2	32	659
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	1.03e-01	1.00e+00	3.209	1	4	132
GO:0031625	ubiquitin protein ligase binding	1.08e-01	1.00e+00	3.145	1	7	138
GO:0030168	platelet activation	1.10e-01	1.00e+00	3.114	1	5	141
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.11e-01	1.00e+00	3.104	1	7	142
GO:0016071	mRNA metabolic process	1.31e-01	1.00e+00	2.844	1	10	170
GO:0044822	poly(A) RNA binding	1.35e-01	1.00e+00	1.611	2	45	799
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.794	1	13	176
GO:0006412	translation	1.37e-01	1.00e+00	2.778	1	12	178
GO:0016070	RNA metabolic process	1.44e-01	1.00e+00	2.699	1	10	188
GO:0043065	positive regulation of apoptotic process	1.54e-01	1.00e+00	2.595	1	7	202
GO:0005654	nucleoplasm	1.57e-01	1.00e+00	1.479	2	68	876
GO:0043231	intracellular membrane-bounded organelle	1.65e-01	1.00e+00	2.485	1	8	218
GO:0005813	centrosome	1.65e-01	1.00e+00	2.492	1	10	217
GO:0005829	cytosol	1.67e-01	1.00e+00	1.035	3	88	1787
GO:0003677	DNA binding	1.78e-01	1.00e+00	1.366	2	52	947
GO:0007411	axon guidance	1.79e-01	1.00e+00	2.365	1	8	237
GO:0005515	protein binding	2.10e-01	1.00e+00	0.566	5	198	4124
GO:0055114	oxidation-reduction process	2.26e-01	1.00e+00	1.987	1	9	308
GO:0000278	mitotic cell cycle	2.30e-01	1.00e+00	1.959	1	28	314
GO:0007596	blood coagulation	2.46e-01	1.00e+00	1.848	1	13	339
GO:0048471	perinuclear region of cytoplasm	2.49e-01	1.00e+00	1.827	1	11	344
GO:0044267	cellular protein metabolic process	2.55e-01	1.00e+00	1.794	1	14	352
GO:0005634	nucleus	2.57e-01	1.00e+00	0.589	4	158	3246
GO:0005730	nucleolus	2.63e-01	1.00e+00	1.004	2	74	1217
GO:0005794	Golgi apparatus	2.94e-01	1.00e+00	1.556	1	6	415
GO:0016032	viral process	3.01e-01	1.00e+00	1.512	1	30	428
GO:0045087	innate immune response	3.16e-01	1.00e+00	1.433	1	12	452
GO:0003700	sequence-specific DNA binding transcription factor activity	3.88e-01	1.00e+00	1.069	1	22	582
GO:0070062	extracellular vesicular exosome	4.00e-01	1.00e+00	0.573	2	51	1641
GO:0005615	extracellular space	4.24e-01	1.00e+00	0.907	1	15	651
GO:0005576	extracellular region	4.30e-01	1.00e+00	0.881	1	15	663
GO:0044281	small molecule metabolic process	5.15e-01	1.00e+00	0.532	1	35	844
GO:0046872	metal ion binding	5.53e-01	1.00e+00	0.386	1	24	934
GO:0005737	cytoplasm	6.80e-01	1.00e+00	-0.109	2	127	2633

chia-Fav

reg-snw-4781

Statistics

Genes (8)

Interactions (7)

Related GO terms (170)