reg-snw-3832

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.189	3.25e-07	4.99e-02	3.78e-02

chia-screen-data-Fav-reg-snw-3832 subnetwork

Genes (15)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	44	-2.477	2.459	21	-	Yes	-
RFWD3	55159	2	-1.534	2.200	94	TF	-	-
APLP2	334	15	-2.732	2.389	4	-	Yes	Yes
FBXL6	26233	28	-2.253	2.689	22	-	Yes	-
CENPA	1058	27	-2.185	2.393	205	TF	Yes	-
SUV39H2	79723	27	-2.307	2.410	21	-	Yes	Yes
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
AGPS	8540	23	-2.424	2.410	27	-	Yes	Yes
TTF2	8458	6	-1.646	2.382	76	TF	-	-
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
[ KIF11 ]	3832	1	-1.372	2.189	48	-	-	-
SFPQ	6421	15	-2.051	2.389	142	TF	Yes	-
EZH2	2146	5	-1.631	2.315	116	TF	-	-

Interactions (19)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
APLP2	334	SFPQ	6421	pd	<	reg.ITFP.txt: no annot
KIF11	3832	TTF2	8458	pd	<	reg.ITFP.txt: no annot
KIF11	3832	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
AGPS	8540	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
CENPA	1058	EZH2	2146	pd	<>	reg.ITFP.txt: no annot
CENPA	1058	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
KIF11	3832	RFWD3	55159	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
CENPA	1058	KIF11	3832	pd	>	reg.ITFP.txt: no annot
KIF11	3832	SFPQ	6421	pd	<	reg.ITFP.txt: no annot
TTF2	8458	AGPS	8540	pd	>	reg.ITFP.txt: no annot
TTF2	8458	RFWD3	55159	pd	<>	reg.ITFP.txt: no annot
CENPA	1058	FBXL6	26233	pd	>	reg.ITFP.txt: no annot
EZH2	2146	KIF11	3832	pd	>	reg.ITFP.txt: no annot
CENPA	1058	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SFPQ	6421	RFWD3	55159	pd	<>	reg.ITFP.txt: no annot

Related GO terms (197)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003747	translation release factor activity	2.20e-06	2.15e-02	9.347	2	2	2
GO:0048511	rhythmic process	2.40e-05	2.34e-01	5.684	3	5	38
GO:0042754	negative regulation of circadian rhythm	3.29e-05	3.21e-01	7.762	2	2	6
GO:0008380	RNA splicing	9.28e-05	9.06e-01	3.980	4	21	165
GO:0006479	protein methylation	1.20e-04	1.00e+00	6.887	2	2	11
GO:0003723	RNA binding	4.38e-04	1.00e+00	3.398	4	22	247
GO:0000976	transcription regulatory region sequence-specific DNA binding	6.47e-04	1.00e+00	5.703	2	3	25
GO:0042752	regulation of circadian rhythm	8.73e-04	1.00e+00	5.489	2	5	29
GO:0006369	termination of RNA polymerase II transcription	1.50e-03	1.00e+00	5.099	2	5	38
GO:0014013	regulation of gliogenesis	1.54e-03	1.00e+00	9.347	1	1	1
GO:0016149	translation release factor activity, codon specific	1.54e-03	1.00e+00	9.347	1	1	1
GO:0045605	negative regulation of epidermal cell differentiation	1.54e-03	1.00e+00	9.347	1	1	1
GO:0000939	condensed chromosome inner kinetochore	1.54e-03	1.00e+00	9.347	1	1	1
GO:0008609	alkylglycerone-phosphate synthase activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0008079	translation termination factor activity	1.54e-03	1.00e+00	9.347	1	1	1
GO:0000775	chromosome, centromeric region	1.74e-03	1.00e+00	4.989	2	6	41
GO:0001047	core promoter binding	1.83e-03	1.00e+00	4.954	2	4	42
GO:0006353	DNA-templated transcription, termination	3.07e-03	1.00e+00	8.347	1	1	2
GO:0008611	ether lipid biosynthetic process	3.07e-03	1.00e+00	8.347	1	1	2
GO:0007100	mitotic centrosome separation	3.07e-03	1.00e+00	8.347	1	2	2
GO:0000785	chromatin	3.58e-03	1.00e+00	4.464	2	6	59
GO:0006415	translational termination	4.07e-03	1.00e+00	4.369	2	2	63
GO:0008762	UDP-N-acetylmuramate dehydrogenase activity	4.60e-03	1.00e+00	7.762	1	1	3
GO:0051154	negative regulation of striated muscle cell differentiation	4.60e-03	1.00e+00	7.762	1	1	3
GO:0036123	histone H3-K9 dimethylation	4.60e-03	1.00e+00	7.762	1	1	3
GO:0000778	condensed nuclear chromosome kinetochore	4.60e-03	1.00e+00	7.762	1	2	3
GO:0070314	G1 to G0 transition	4.60e-03	1.00e+00	7.762	1	1	3
GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	4.60e-03	1.00e+00	7.762	1	1	3
GO:0046914	transition metal ion binding	4.60e-03	1.00e+00	7.762	1	1	3
GO:2000001	regulation of DNA damage checkpoint	4.60e-03	1.00e+00	7.762	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	4.60e-03	1.00e+00	7.762	1	1	3
GO:0046976	histone methyltransferase activity (H3-K27 specific)	6.13e-03	1.00e+00	7.347	1	1	4
GO:0097452	GAIT complex	6.13e-03	1.00e+00	7.347	1	2	4
GO:0006449	regulation of translational termination	6.13e-03	1.00e+00	7.347	1	1	4
GO:0006333	chromatin assembly or disassembly	6.13e-03	1.00e+00	7.347	1	1	4
GO:0036124	histone H3-K9 trimethylation	6.13e-03	1.00e+00	7.347	1	2	4
GO:0070734	histone H3-K27 methylation	6.13e-03	1.00e+00	7.347	1	1	4
GO:0007176	regulation of epidermal growth factor-activated receptor activity	6.13e-03	1.00e+00	7.347	1	1	4
GO:0003682	chromatin binding	6.14e-03	1.00e+00	2.954	3	15	252
GO:0030529	ribonucleoprotein complex	6.81e-03	1.00e+00	3.989	2	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.14e-03	1.00e+00	3.954	2	5	84
GO:0004521	endoribonuclease activity	7.66e-03	1.00e+00	7.025	1	1	5
GO:0008610	lipid biosynthetic process	7.66e-03	1.00e+00	7.025	1	1	5
GO:0006398	histone mRNA 3'-end processing	7.66e-03	1.00e+00	7.025	1	1	5
GO:0021695	cerebellar cortex development	7.66e-03	1.00e+00	7.025	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	7.66e-03	1.00e+00	7.025	1	2	5
GO:0071168	protein localization to chromatin	7.66e-03	1.00e+00	7.025	1	2	5
GO:0071204	histone pre-mRNA 3'end processing complex	7.66e-03	1.00e+00	7.025	1	1	5
GO:0042382	paraspeckles	7.66e-03	1.00e+00	7.025	1	3	5
GO:0097371	MDM2/MDM4 family protein binding	7.66e-03	1.00e+00	7.025	1	1	5
GO:0005654	nucleoplasm	8.04e-03	1.00e+00	1.894	5	68	876
GO:0046974	histone methyltransferase activity (H3-K9 specific)	9.18e-03	1.00e+00	6.762	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	9.18e-03	1.00e+00	6.762	1	2	6
GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter	1.07e-02	1.00e+00	6.539	1	1	7
GO:0042054	histone methyltransferase activity	1.07e-02	1.00e+00	6.539	1	1	7
GO:0007140	male meiosis	1.07e-02	1.00e+00	6.539	1	1	7
GO:0008409	5'-3' exonuclease activity	1.07e-02	1.00e+00	6.539	1	2	7
GO:0007617	mating behavior	1.07e-02	1.00e+00	6.539	1	1	7
GO:0000780	condensed nuclear chromosome, centromeric region	1.07e-02	1.00e+00	6.539	1	1	7
GO:0045814	negative regulation of gene expression, epigenetic	1.07e-02	1.00e+00	6.539	1	1	7
GO:0051382	kinetochore assembly	1.07e-02	1.00e+00	6.539	1	2	7
GO:0000380	alternative mRNA splicing, via spliceosome	1.07e-02	1.00e+00	6.539	1	2	7
GO:0045892	negative regulation of transcription, DNA-templated	1.15e-02	1.00e+00	2.623	3	17	317
GO:0006397	mRNA processing	1.20e-02	1.00e+00	3.565	2	12	110
GO:0006878	cellular copper ion homeostasis	1.22e-02	1.00e+00	6.347	1	1	8
GO:0090307	spindle assembly involved in mitosis	1.22e-02	1.00e+00	6.347	1	2	8
GO:0071949	FAD binding	1.22e-02	1.00e+00	6.347	1	1	8
GO:0006379	mRNA cleavage	1.37e-02	1.00e+00	6.177	1	2	9
GO:0048387	negative regulation of retinoic acid receptor signaling pathway	1.37e-02	1.00e+00	6.177	1	2	9
GO:0031571	mitotic G1 DNA damage checkpoint	1.37e-02	1.00e+00	6.177	1	1	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	1.37e-02	1.00e+00	6.177	1	3	9
GO:0005515	protein binding	1.49e-02	1.00e+00	0.796	11	198	4124
GO:0001967	suckling behavior	1.53e-02	1.00e+00	6.025	1	4	10
GO:0007051	spindle organization	1.53e-02	1.00e+00	6.025	1	1	10
GO:0008143	poly(A) binding	1.53e-02	1.00e+00	6.025	1	2	10
GO:0008574	plus-end-directed microtubule motor activity	1.53e-02	1.00e+00	6.025	1	1	10
GO:0000398	mRNA splicing, via spliceosome	1.60e-02	1.00e+00	3.347	2	15	128
GO:0008023	transcription elongation factor complex	1.68e-02	1.00e+00	5.887	1	2	11
GO:0045120	pronucleus	1.68e-02	1.00e+00	5.887	1	3	11
GO:0000132	establishment of mitotic spindle orientation	1.83e-02	1.00e+00	5.762	1	2	12
GO:0035098	ESC/E(Z) complex	1.98e-02	1.00e+00	5.646	1	1	13
GO:0035861	site of double-strand break	1.98e-02	1.00e+00	5.646	1	1	13
GO:0043393	regulation of protein binding	2.13e-02	1.00e+00	5.539	1	2	14
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	2.28e-02	1.00e+00	5.440	1	2	15
GO:0070932	histone H3 deacetylation	2.28e-02	1.00e+00	5.440	1	2	15
GO:0005782	peroxisomal matrix	2.43e-02	1.00e+00	5.347	1	1	16
GO:0043022	ribosome binding	2.58e-02	1.00e+00	5.259	1	2	17
GO:0007052	mitotic spindle organization	2.58e-02	1.00e+00	5.259	1	3	17
GO:0006378	mRNA polyadenylation	2.73e-02	1.00e+00	5.177	1	3	18
GO:0032320	positive regulation of Ras GTPase activity	2.73e-02	1.00e+00	5.177	1	2	18
GO:0006306	DNA methylation	2.88e-02	1.00e+00	5.099	1	1	19
GO:0000166	nucleotide binding	2.91e-02	1.00e+00	2.887	2	13	176
GO:0044822	poly(A) RNA binding	2.93e-02	1.00e+00	1.704	4	45	799
GO:0004842	ubiquitin-protein transferase activity	3.00e-02	1.00e+00	2.863	2	17	179
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.03e-02	1.00e+00	2.099	3	29	456
GO:0034080	CENP-A containing nucleosome assembly	3.03e-02	1.00e+00	5.025	1	2	20
GO:0071902	positive regulation of protein serine/threonine kinase activity	3.03e-02	1.00e+00	5.025	1	2	20
GO:0010718	positive regulation of epithelial to mesenchymal transition	3.03e-02	1.00e+00	5.025	1	2	20
GO:0071346	cellular response to interferon-gamma	3.03e-02	1.00e+00	5.025	1	2	20
GO:0005720	nuclear heterochromatin	3.03e-02	1.00e+00	5.025	1	3	20
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	3.18e-02	1.00e+00	4.954	1	2	21
GO:0016567	protein ubiquitination	3.28e-02	1.00e+00	2.792	2	14	188
GO:0005876	spindle microtubule	3.63e-02	1.00e+00	4.762	1	4	24
GO:0030901	midbrain development	3.77e-02	1.00e+00	4.703	1	1	25
GO:0006281	DNA repair	3.78e-02	1.00e+00	2.681	2	24	203
GO:0050885	neuromuscular process controlling balance	4.22e-02	1.00e+00	4.539	1	1	28
GO:0006200	ATP catabolic process	4.34e-02	1.00e+00	2.572	2	13	219
GO:0008094	DNA-dependent ATPase activity	4.37e-02	1.00e+00	4.489	1	6	29
GO:0008026	ATP-dependent helicase activity	4.37e-02	1.00e+00	4.489	1	3	29
GO:0005778	peroxisomal membrane	4.37e-02	1.00e+00	4.489	1	3	29
GO:0010212	response to ionizing radiation	4.51e-02	1.00e+00	4.440	1	3	30
GO:0031490	chromatin DNA binding	4.66e-02	1.00e+00	4.392	1	1	31
GO:0005871	kinesin complex	4.66e-02	1.00e+00	4.392	1	3	31
GO:0017148	negative regulation of translation	4.95e-02	1.00e+00	4.302	1	5	33
GO:0003677	DNA binding	5.04e-02	1.00e+00	1.459	4	52	947
GO:0000786	nucleosome	5.10e-02	1.00e+00	4.259	1	2	34
GO:0043406	positive regulation of MAP kinase activity	5.25e-02	1.00e+00	4.217	1	1	35
GO:0031124	mRNA 3'-end processing	5.25e-02	1.00e+00	4.217	1	4	35
GO:0070301	cellular response to hydrogen peroxide	5.25e-02	1.00e+00	4.217	1	1	35
GO:0030900	forebrain development	5.39e-02	1.00e+00	4.177	1	2	36
GO:0003777	microtubule motor activity	5.83e-02	1.00e+00	4.061	1	3	39
GO:0007018	microtubule-based movement	5.83e-02	1.00e+00	4.061	1	2	39
GO:0006396	RNA processing	5.98e-02	1.00e+00	4.025	1	4	40
GO:0004867	serine-type endopeptidase inhibitor activity	6.27e-02	1.00e+00	3.954	1	1	42
GO:0006406	mRNA export from nucleus	6.55e-02	1.00e+00	3.887	1	7	44
GO:0002039	p53 binding	6.70e-02	1.00e+00	3.855	1	4	45
GO:0008203	cholesterol metabolic process	6.99e-02	1.00e+00	3.792	1	2	47
GO:0007626	locomotory behavior	6.99e-02	1.00e+00	3.792	1	1	47
GO:0007059	chromosome segregation	7.42e-02	1.00e+00	3.703	1	4	50
GO:0005777	peroxisome	7.42e-02	1.00e+00	3.703	1	2	50
GO:0006310	DNA recombination	7.42e-02	1.00e+00	3.703	1	8	50
GO:0006334	nucleosome assembly	7.56e-02	1.00e+00	3.674	1	4	51
GO:0006338	chromatin remodeling	8.13e-02	1.00e+00	3.565	1	7	55
GO:0005681	spliceosomal complex	8.13e-02	1.00e+00	3.565	1	8	55
GO:0042826	histone deacetylase binding	8.55e-02	1.00e+00	3.489	1	5	58
GO:0071013	catalytic step 2 spliceosome	8.98e-02	1.00e+00	3.416	1	5	61
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	9.40e-02	1.00e+00	3.347	1	3	64
GO:0008270	zinc ion binding	9.56e-02	1.00e+00	1.426	3	39	727
GO:0000922	spindle pole	9.96e-02	1.00e+00	3.259	1	4	68
GO:0006325	chromatin organization	1.02e-01	1.00e+00	3.217	1	4	70
GO:0010951	negative regulation of endopeptidase activity	1.04e-01	1.00e+00	3.197	1	2	71
GO:0016020	membrane	1.04e-01	1.00e+00	1.109	4	56	1207
GO:0016363	nuclear matrix	1.07e-01	1.00e+00	3.157	1	10	73
GO:0001649	osteoblast differentiation	1.08e-01	1.00e+00	3.137	1	5	74
GO:0071456	cellular response to hypoxia	1.11e-01	1.00e+00	3.099	1	2	76
GO:0016605	PML body	1.15e-01	1.00e+00	3.043	1	5	79
GO:0042127	regulation of cell proliferation	1.16e-01	1.00e+00	3.025	1	4	80
GO:0005819	spindle	1.16e-01	1.00e+00	3.025	1	6	80
GO:0044255	cellular lipid metabolic process	1.28e-01	1.00e+00	2.871	1	2	89
GO:0008201	heparin binding	1.31e-01	1.00e+00	2.839	1	4	91
GO:0016032	viral process	1.38e-01	1.00e+00	1.605	2	30	428
GO:0008017	microtubule binding	1.39e-01	1.00e+00	2.747	1	9	97
GO:0016887	ATPase activity	1.43e-01	1.00e+00	2.703	1	5	100
GO:0000790	nuclear chromatin	1.55e-01	1.00e+00	2.578	1	9	109
GO:0003924	GTPase activity	1.68e-01	1.00e+00	2.452	1	7	119
GO:0000082	G1/S transition of mitotic cell cycle	1.76e-01	1.00e+00	2.381	1	4	125
GO:0006184	GTP catabolic process	1.82e-01	1.00e+00	2.324	1	7	130
GO:0032403	protein complex binding	1.82e-01	1.00e+00	2.324	1	5	130
GO:0005737	cytoplasm	1.95e-01	1.00e+00	0.569	6	127	2633
GO:0010467	gene expression	1.97e-01	1.00e+00	1.283	2	49	535
GO:0044212	transcription regulatory region DNA binding	1.99e-01	1.00e+00	2.187	1	13	143
GO:0005622	intracellular	2.01e-01	1.00e+00	2.167	1	2	145
GO:0016874	ligase activity	2.02e-01	1.00e+00	2.157	1	11	146
GO:0005874	microtubule	2.23e-01	1.00e+00	1.998	1	10	163
GO:0006351	transcription, DNA-templated	2.24e-01	1.00e+00	0.860	3	47	1076
GO:0007067	mitotic nuclear division	2.26e-01	1.00e+00	1.980	1	9	165
GO:0016071	mRNA metabolic process	2.32e-01	1.00e+00	1.937	1	10	170
GO:0006412	translation	2.41e-01	1.00e+00	1.871	1	12	178
GO:0008152	metabolic process	2.46e-01	1.00e+00	1.839	1	6	182
GO:0016070	RNA metabolic process	2.53e-01	1.00e+00	1.792	1	10	188
GO:0005525	GTP binding	2.64e-01	1.00e+00	1.724	1	12	197
GO:0030154	cell differentiation	2.72e-01	1.00e+00	1.674	1	5	204
GO:0043231	intracellular membrane-bounded organelle	2.87e-01	1.00e+00	1.578	1	8	218
GO:0030198	extracellular matrix organization	2.91e-01	1.00e+00	1.559	1	7	221
GO:0007186	G-protein coupled receptor signaling pathway	3.00e-01	1.00e+00	1.507	1	4	229
GO:0006355	regulation of transcription, DNA-templated	3.02e-01	1.00e+00	0.865	2	31	715
GO:0019901	protein kinase binding	3.03e-01	1.00e+00	1.489	1	8	232
GO:0006508	proteolysis	3.37e-01	1.00e+00	1.302	1	11	264
GO:0046982	protein heterodimerization activity	3.38e-01	1.00e+00	1.297	1	11	265
GO:0043565	sequence-specific DNA binding	3.49e-01	1.00e+00	1.243	1	8	275
GO:0005634	nucleus	3.79e-01	1.00e+00	0.267	6	158	3246
GO:0055114	oxidation-reduction process	3.82e-01	1.00e+00	1.080	1	9	308
GO:0000278	mitotic cell cycle	3.88e-01	1.00e+00	1.052	1	28	314
GO:0005524	ATP binding	4.04e-01	1.00e+00	0.546	2	37	892
GO:0007596	blood coagulation	4.12e-01	1.00e+00	0.941	1	13	339
GO:0006366	transcription from RNA polymerase II promoter	4.13e-01	1.00e+00	0.933	1	23	341
GO:0044267	cellular protein metabolic process	4.24e-01	1.00e+00	0.887	1	14	352
GO:0042802	identical protein binding	4.26e-01	1.00e+00	0.879	1	15	354
GO:0005783	endoplasmic reticulum	4.50e-01	1.00e+00	0.773	1	12	381
GO:0005829	cytosol	5.36e-01	1.00e+00	0.128	3	88	1787
GO:0005730	nucleolus	5.74e-01	1.00e+00	0.097	2	74	1217
GO:0005739	mitochondrion	6.50e-01	1.00e+00	-0.018	1	32	659
GO:0044281	small molecule metabolic process	7.43e-01	1.00e+00	-0.375	1	35	844
GO:0046872	metal ion binding	7.79e-01	1.00e+00	-0.521	1	24	934
GO:0016021	integral component of membrane	9.22e-01	1.00e+00	-1.229	1	19	1526
GO:0070062	extracellular vesicular exosome	9.37e-01	1.00e+00	-1.334	1	51	1641
GO:0005886	plasma membrane	9.52e-01	1.00e+00	-1.454	1	46	1784

chia-Fav

reg-snw-3832

Statistics

Genes (15)

Interactions (19)

Related GO terms (197)