reg-snw-2551

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.238	1.83e-07	3.70e-02	2.83e-02

chia-screen-data-Fav-reg-snw-2551 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RRAS	6237	1	-2.073	2.238	1	-	Yes	Yes
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
[ GABPA ]	2551	1	-1.442	2.238	58	TF	-	-
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
KIR3DL1	3811	2	-2.465	2.238	9	-	Yes	Yes
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
YY1	7528	2	-2.572	2.238	54	TF	Yes	Yes
TIPRL	261726	1	-1.553	2.238	22	-	-	-
CLASP1	23332	10	-2.365	2.459	39	TF	Yes	-
PAPOLA	10914	9	-1.996	2.455	19	-	-	-

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
GABPA	2551	KIR3DL1	3811	pd	>	reg.TRANSFAC.txt: no annot
SYNCRIP	10492	PAPOLA	10914	pd	>	reg.ITFP.txt: no annot
GABPA	2551	PAPOLA	10914	pd	>	reg.ITFP.txt: no annot
GABPA	2551	RRAS	6237	pd	>	reg.TRANSFAC.txt: no annot
PAPOLA	10914	CLASP1	23332	pd	<	reg.ITFP.txt: no annot
KIR3DL1	3811	YY1	7528	pd	<	reg.TRANSFAC.txt: no annot
GABPA	2551	TIPRL	261726	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot

Related GO terms (141)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003723	RNA binding	2.26e-06	2.21e-02	4.305	5	22	247
GO:0000398	mRNA splicing, via spliceosome	2.47e-04	1.00e+00	4.516	3	15	128
GO:0008380	RNA splicing	5.21e-04	1.00e+00	4.150	3	21	165
GO:0031124	mRNA 3'-end processing	5.52e-04	1.00e+00	5.802	2	4	35
GO:0006369	termination of RNA polymerase II transcription	6.51e-04	1.00e+00	5.684	2	5	38
GO:0016149	translation release factor activity, codon specific	1.02e-03	1.00e+00	9.931	1	1	1
GO:0031592	centrosomal corona	1.02e-03	1.00e+00	9.931	1	1	1
GO:0008079	translation termination factor activity	1.02e-03	1.00e+00	9.931	1	1	1
GO:0002521	leukocyte differentiation	1.02e-03	1.00e+00	9.931	1	1	1
GO:0031111	negative regulation of microtubule polymerization or depolymerization	2.05e-03	1.00e+00	8.931	1	1	2
GO:0034696	response to prostaglandin F	2.05e-03	1.00e+00	8.931	1	1	2
GO:0030981	cortical microtubule cytoskeleton	2.05e-03	1.00e+00	8.931	1	1	2
GO:0003747	translation release factor activity	2.05e-03	1.00e+00	8.931	1	2	2
GO:0006403	RNA localization	2.05e-03	1.00e+00	8.931	1	1	2
GO:0051294	establishment of spindle orientation	2.05e-03	1.00e+00	8.931	1	1	2
GO:0030109	HLA-B specific inhibitory MHC class I receptor activity	2.05e-03	1.00e+00	8.931	1	1	2
GO:0034048	negative regulation of protein phosphatase type 2A activity	2.05e-03	1.00e+00	8.931	1	1	2
GO:0030529	ribonucleoprotein complex	3.00e-03	1.00e+00	4.574	2	5	82
GO:0097452	GAIT complex	4.09e-03	1.00e+00	7.931	1	2	4
GO:0004652	polynucleotide adenylyltransferase activity	4.09e-03	1.00e+00	7.931	1	1	4
GO:0006449	regulation of translational termination	4.09e-03	1.00e+00	7.931	1	1	4
GO:0043631	RNA polyadenylation	4.09e-03	1.00e+00	7.931	1	1	4
GO:0043515	kinetochore binding	4.09e-03	1.00e+00	7.931	1	2	4
GO:0006366	transcription from RNA polymerase II promoter	4.22e-03	1.00e+00	3.103	3	23	341
GO:0004521	endoribonuclease activity	5.11e-03	1.00e+00	7.610	1	1	5
GO:0010458	exit from mitosis	5.11e-03	1.00e+00	7.610	1	2	5
GO:0006398	histone mRNA 3'-end processing	5.11e-03	1.00e+00	7.610	1	1	5
GO:0005828	kinetochore microtubule	5.11e-03	1.00e+00	7.610	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	5.11e-03	1.00e+00	7.610	1	2	5
GO:0071204	histone pre-mRNA 3'end processing complex	5.11e-03	1.00e+00	7.610	1	1	5
GO:0031023	microtubule organizing center organization	5.11e-03	1.00e+00	7.610	1	1	5
GO:0045653	negative regulation of megakaryocyte differentiation	6.13e-03	1.00e+00	7.347	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	6.13e-03	1.00e+00	7.347	1	2	6
GO:0051896	regulation of protein kinase B signaling	7.15e-03	1.00e+00	7.124	1	1	7
GO:0008409	5'-3' exonuclease activity	7.15e-03	1.00e+00	7.124	1	2	7
GO:0000400	four-way junction DNA binding	7.15e-03	1.00e+00	7.124	1	3	7
GO:0031011	Ino80 complex	8.17e-03	1.00e+00	6.931	1	3	8
GO:0044212	transcription regulatory region DNA binding	8.87e-03	1.00e+00	3.772	2	13	143
GO:0034453	microtubule anchoring	9.18e-03	1.00e+00	6.762	1	1	9
GO:0010225	response to UV-C	9.18e-03	1.00e+00	6.762	1	2	9
GO:0006379	mRNA cleavage	9.18e-03	1.00e+00	6.762	1	2	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	9.18e-03	1.00e+00	6.762	1	3	9
GO:0008143	poly(A) binding	1.02e-02	1.00e+00	6.610	1	2	10
GO:0001578	microtubule bundle formation	1.02e-02	1.00e+00	6.610	1	2	10
GO:0051010	microtubule plus-end binding	1.12e-02	1.00e+00	6.472	1	2	11
GO:0007026	negative regulation of microtubule depolymerization	1.12e-02	1.00e+00	6.472	1	2	11
GO:0007020	microtubule nucleation	1.12e-02	1.00e+00	6.472	1	1	11
GO:0006479	protein methylation	1.12e-02	1.00e+00	6.472	1	2	11
GO:0070372	regulation of ERK1 and ERK2 cascade	1.22e-02	1.00e+00	6.347	1	1	12
GO:0051276	chromosome organization	1.22e-02	1.00e+00	6.347	1	2	12
GO:0048593	camera-type eye morphogenesis	1.32e-02	1.00e+00	6.231	1	1	13
GO:0003713	transcription coactivator activity	1.44e-02	1.00e+00	3.408	2	21	184
GO:0010467	gene expression	1.47e-02	1.00e+00	2.453	3	49	535
GO:0043022	ribosome binding	1.73e-02	1.00e+00	5.844	1	2	17
GO:0030154	cell differentiation	1.75e-02	1.00e+00	3.259	2	5	204
GO:0005515	protein binding	1.78e-02	1.00e+00	0.922	8	198	4124
GO:0006378	mRNA polyadenylation	1.83e-02	1.00e+00	5.762	1	3	18
GO:0031519	PcG protein complex	1.83e-02	1.00e+00	5.762	1	3	18
GO:0007163	establishment or maintenance of cell polarity	2.03e-02	1.00e+00	5.610	1	1	20
GO:0071346	cellular response to interferon-gamma	2.03e-02	1.00e+00	5.610	1	2	20
GO:0000077	DNA damage checkpoint	2.13e-02	1.00e+00	5.539	1	4	21
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	2.13e-02	1.00e+00	5.539	1	2	21
GO:0060325	face morphogenesis	2.23e-02	1.00e+00	5.472	1	1	22
GO:0007411	axon guidance	2.32e-02	1.00e+00	3.043	2	8	237
GO:0005881	cytoplasmic microtubule	2.43e-02	1.00e+00	5.347	1	3	24
GO:0005876	spindle microtubule	2.43e-02	1.00e+00	5.347	1	4	24
GO:0030145	manganese ion binding	2.63e-02	1.00e+00	5.231	1	3	26
GO:0034644	cellular response to UV	2.83e-02	1.00e+00	5.124	1	1	28
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	3.03e-02	1.00e+00	5.025	1	1	30
GO:0017148	negative regulation of translation	3.33e-02	1.00e+00	4.887	1	5	33
GO:0019003	GDP binding	3.43e-02	1.00e+00	4.844	1	2	34
GO:0000226	microtubule cytoskeleton organization	3.63e-02	1.00e+00	4.762	1	1	36
GO:0006396	RNA processing	4.02e-02	1.00e+00	4.610	1	4	40
GO:0000724	double-strand break repair via homologous recombination	4.22e-02	1.00e+00	4.539	1	5	42
GO:0006406	mRNA export from nucleus	4.42e-02	1.00e+00	4.472	1	7	44
GO:0051301	cell division	4.91e-02	1.00e+00	4.317	1	2	49
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	5.01e-02	1.00e+00	4.288	1	2	50
GO:0005654	nucleoplasm	5.35e-02	1.00e+00	1.742	3	68	876
GO:0000776	kinetochore	5.49e-02	1.00e+00	4.150	1	8	55
GO:0050776	regulation of immune response	5.49e-02	1.00e+00	4.150	1	2	55
GO:0000777	condensed chromosome kinetochore	5.69e-02	1.00e+00	4.099	1	6	57
GO:0007265	Ras protein signal transduction	5.88e-02	1.00e+00	4.049	1	3	59
GO:0030336	negative regulation of cell migration	5.98e-02	1.00e+00	4.025	1	3	60
GO:0009952	anterior/posterior pattern specification	5.98e-02	1.00e+00	4.025	1	3	60
GO:0071013	catalytic step 2 spliceosome	6.08e-02	1.00e+00	4.001	1	5	61
GO:0006415	translational termination	6.27e-02	1.00e+00	3.954	1	2	63
GO:0016363	nuclear matrix	7.23e-02	1.00e+00	3.742	1	10	73
GO:0001649	osteoblast differentiation	7.33e-02	1.00e+00	3.722	1	5	74
GO:0005938	cell cortex	7.61e-02	1.00e+00	3.665	1	6	77
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	7.64e-02	1.00e+00	2.099	2	29	456
GO:0045766	positive regulation of angiogenesis	7.71e-02	1.00e+00	3.646	1	4	78
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	8.28e-02	1.00e+00	3.539	1	5	84
GO:0000086	G2/M transition of mitotic cell cycle	9.51e-02	1.00e+00	3.332	1	7	97
GO:0008017	microtubule binding	9.51e-02	1.00e+00	3.332	1	9	97
GO:0000790	nuclear chromatin	1.06e-01	1.00e+00	3.163	1	9	109
GO:0000287	magnesium ion binding	1.12e-01	1.00e+00	3.086	1	4	115
GO:0003924	GTPase activity	1.15e-01	1.00e+00	3.037	1	7	119
GO:0003700	sequence-specific DNA binding transcription factor activity	1.16e-01	1.00e+00	1.747	2	22	582
GO:0006974	cellular response to DNA damage stimulus	1.17e-01	1.00e+00	3.013	1	11	121
GO:0006184	GTP catabolic process	1.25e-01	1.00e+00	2.909	1	7	130
GO:0032403	protein complex binding	1.25e-01	1.00e+00	2.909	1	5	130
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	1.27e-01	1.00e+00	2.887	1	4	132
GO:0003714	transcription corepressor activity	1.32e-01	1.00e+00	2.833	1	5	137
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.36e-01	1.00e+00	2.782	1	7	142
GO:0005667	transcription factor complex	1.41e-01	1.00e+00	2.732	1	8	147
GO:0001701	in utero embryonic development	1.47e-01	1.00e+00	2.665	1	7	154
GO:0007283	spermatogenesis	1.59e-01	1.00e+00	2.539	1	4	168
GO:0016071	mRNA metabolic process	1.61e-01	1.00e+00	2.522	1	10	170
GO:0000166	nucleotide binding	1.66e-01	1.00e+00	2.472	1	13	176
GO:0006412	translation	1.68e-01	1.00e+00	2.456	1	12	178
GO:0016070	RNA metabolic process	1.77e-01	1.00e+00	2.377	1	10	188
GO:0005525	GTP binding	1.84e-01	1.00e+00	2.309	1	12	197
GO:0006955	immune response	1.87e-01	1.00e+00	2.288	1	2	200
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.90e-01	1.00e+00	2.266	1	14	203
GO:0044822	poly(A) RNA binding	1.95e-01	1.00e+00	1.289	2	45	799
GO:0007268	synaptic transmission	1.99e-01	1.00e+00	2.190	1	7	214
GO:0005813	centrosome	2.01e-01	1.00e+00	2.170	1	10	217
GO:0043231	intracellular membrane-bounded organelle	2.02e-01	1.00e+00	2.163	1	8	218
GO:0003682	chromatin binding	2.30e-01	1.00e+00	1.954	1	15	252
GO:0046982	protein heterodimerization activity	2.41e-01	1.00e+00	1.882	1	11	265
GO:0003677	DNA binding	2.52e-01	1.00e+00	1.044	2	52	947
GO:0005925	focal adhesion	2.54e-01	1.00e+00	1.792	1	14	282
GO:0000278	mitotic cell cycle	2.79e-01	1.00e+00	1.637	1	28	314
GO:0044267	cellular protein metabolic process	3.07e-01	1.00e+00	1.472	1	14	352
GO:0005783	endoplasmic reticulum	3.28e-01	1.00e+00	1.358	1	12	381
GO:0005794	Golgi apparatus	3.52e-01	1.00e+00	1.235	1	6	415
GO:0016020	membrane	3.56e-01	1.00e+00	0.694	2	56	1207
GO:0005730	nucleolus	3.60e-01	1.00e+00	0.682	2	74	1217
GO:0016032	viral process	3.61e-01	1.00e+00	1.190	1	30	428
GO:0005634	nucleus	4.38e-01	1.00e+00	0.267	4	158	3246
GO:0005887	integral component of plasma membrane	4.55e-01	1.00e+00	0.764	1	8	575
GO:0007165	signal transduction	4.80e-01	1.00e+00	0.660	1	24	618
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	4.95e-01	1.00e+00	0.601	1	29	644
GO:0070062	extracellular vesicular exosome	5.20e-01	1.00e+00	0.251	2	51	1641
GO:0005737	cytoplasm	5.33e-01	1.00e+00	0.154	3	127	2633
GO:0008270	zinc ion binding	5.39e-01	1.00e+00	0.426	1	39	727
GO:0005886	plasma membrane	5.70e-01	1.00e+00	0.131	2	46	1784
GO:0005829	cytosol	5.71e-01	1.00e+00	0.128	2	88	1787
GO:0005524	ATP binding	6.16e-01	1.00e+00	0.131	1	37	892
GO:0046872	metal ion binding	6.34e-01	1.00e+00	0.064	1	24	934
GO:0006351	transcription, DNA-templated	6.89e-01	1.00e+00	-0.140	1	47	1076

chia-Fav

reg-snw-2551

Statistics

Genes (10)

Interactions (9)

Related GO terms (141)