int-snw-79913

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.996	2.77e-17	6.16e-05	7.87e-04

chia-screen-data-Fav-int-snw-79913 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
MCRS1	10445	14	-2.660	3.079	63	Yes	Yes
COPS4	51138	3	-3.198	3.043	47	Yes	Yes
TFPT	29844	1	-2.084	2.996	23	Yes	-
[ ACTR5 ]	79913	1	-1.887	2.996	35	-	-
INO80E	283899	10	-2.663	3.079	20	Yes	-
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
YY1	7528	24	-2.572	3.120	114	Yes	Yes
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
GPS1	2873	3	-3.621	3.043	26	Yes	Yes

Interactions (18)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
YY1	7528	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
NFRKB	4798	MCRS1	10445	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
MCRS1	10445	ACTR5	79913	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
TFPT	29844	ACTR5	79913	pp	--	int.I2D: BioGrid
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
GPS1	2873	COPS4	51138	pp	--	int.Intact: MI:0915(physical association); int.I2D: BIND, IntAct, MGI
NFRKB	4798	YY1	7528	pp	--	int.I2D: BioGrid
YY1	7528	ACTR5	79913	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
MCRS1	10445	TFPT	29844	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
MCRS1	10445	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
NFRKB	4798	ACTR5	79913	pp	--	int.I2D: BioGrid
COPS4	51138	ACTR5	79913	pp	--	int.I2D: MINT_Fly, BioGrid_Fly, BIND_Fly, FlyLow, IntAct_Fly
TFPT	29844	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
NFRKB	4798	TFPT	29844	pp	--	int.I2D: BioGrid
ACTR5	79913	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, IntAct
NFRKB	4798	INO80E	283899	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid
YY1	7528	TFPT	29844	pp	--	int.I2D: BioGrid
YY1	7528	MCRS1	10445	pp	--	int.I2D: BioGrid

Related GO terms (90)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0031011	Ino80 complex	2.02e-17	2.91e-13	9.424	6	6	14
GO:0006310	DNA recombination	1.97e-10	2.85e-06	6.946	5	7	65
GO:0006355	regulation of transcription, DNA-templated	7.53e-06	1.09e-01	3.270	6	43	997
GO:0006281	DNA repair	1.23e-05	1.77e-01	4.618	4	14	261
GO:0010388	cullin deneddylation	1.24e-05	1.79e-01	8.476	2	5	9
GO:0005634	nucleus	3.13e-05	4.52e-01	1.662	9	159	4559
GO:0008180	COP9 signalosome	1.92e-04	1.00e+00	6.559	2	7	34
GO:0005515	protein binding	3.85e-04	1.00e+00	1.260	9	198	6024
GO:0060795	cell fate commitment involved in formation of primary germ layer	6.24e-04	1.00e+00	10.646	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	6.24e-04	1.00e+00	10.646	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	6.24e-04	1.00e+00	10.646	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	6.24e-04	1.00e+00	10.646	1	1	1
GO:0006351	transcription, DNA-templated	8.97e-04	1.00e+00	2.470	5	57	1446
GO:0034696	response to prostaglandin F	1.25e-03	1.00e+00	9.646	1	1	2
GO:0009786	regulation of asymmetric cell division	1.25e-03	1.00e+00	9.646	1	1	2
GO:0006403	RNA localization	1.25e-03	1.00e+00	9.646	1	1	2
GO:0005730	nucleolus	1.61e-03	1.00e+00	2.288	5	66	1641
GO:0060913	cardiac cell fate determination	1.87e-03	1.00e+00	9.061	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.87e-03	1.00e+00	9.061	1	1	3
GO:0000338	protein deneddylation	1.87e-03	1.00e+00	9.061	1	1	3
GO:0001714	endodermal cell fate specification	3.12e-03	1.00e+00	8.324	1	1	5
GO:0070914	UV-damage excision repair	4.36e-03	1.00e+00	7.839	1	1	7
GO:0003677	DNA binding	4.51e-03	1.00e+00	2.396	4	49	1218
GO:0044212	transcription regulatory region DNA binding	4.60e-03	1.00e+00	4.254	2	17	168
GO:0005667	transcription factor complex	4.98e-03	1.00e+00	4.195	2	17	175
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	5.60e-03	1.00e+00	7.476	1	5	9
GO:0000400	four-way junction DNA binding	5.60e-03	1.00e+00	7.476	1	1	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	5.60e-03	1.00e+00	7.476	1	5	9
GO:0010225	response to UV-C	5.60e-03	1.00e+00	7.476	1	2	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	5.60e-03	1.00e+00	7.476	1	5	9
GO:0035413	positive regulation of catenin import into nucleus	6.22e-03	1.00e+00	7.324	1	2	10
GO:0060391	positive regulation of SMAD protein import into nucleus	6.85e-03	1.00e+00	7.187	1	4	11
GO:0035198	miRNA binding	7.47e-03	1.00e+00	7.061	1	1	12
GO:0005095	GTPase inhibitor activity	8.09e-03	1.00e+00	6.946	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	8.09e-03	1.00e+00	6.946	1	2	13
GO:0043981	histone H4-K5 acetylation	9.32e-03	1.00e+00	6.739	1	5	15
GO:0001824	blastocyst development	9.32e-03	1.00e+00	6.739	1	2	15
GO:0043982	histone H4-K8 acetylation	9.32e-03	1.00e+00	6.739	1	5	15
GO:0048593	camera-type eye morphogenesis	9.94e-03	1.00e+00	6.646	1	1	16
GO:0051276	chromosome organization	9.94e-03	1.00e+00	6.646	1	2	16
GO:0043984	histone H4-K16 acetylation	1.18e-02	1.00e+00	6.398	1	5	19
GO:0000123	histone acetyltransferase complex	1.30e-02	1.00e+00	6.254	1	6	21
GO:0031519	PcG protein complex	1.55e-02	1.00e+00	6.002	1	1	25
GO:0000188	inactivation of MAPK activity	1.67e-02	1.00e+00	5.891	1	1	27
GO:0071339	MLL1 complex	1.67e-02	1.00e+00	5.891	1	6	27
GO:0034644	cellular response to UV	1.86e-02	1.00e+00	5.739	1	1	30
GO:0035019	somatic stem cell maintenance	2.47e-02	1.00e+00	5.324	1	6	40
GO:0006366	transcription from RNA polymerase II promoter	2.65e-02	1.00e+00	2.935	2	30	419
GO:0005884	actin filament	2.71e-02	1.00e+00	5.187	1	3	44
GO:0007254	JNK cascade	3.02e-02	1.00e+00	5.031	1	2	49
GO:0009611	response to wounding	3.20e-02	1.00e+00	4.946	1	5	52
GO:0000724	double-strand break repair via homologous recombination	3.38e-02	1.00e+00	4.865	1	2	55
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	3.62e-02	1.00e+00	4.764	1	5	59
GO:0006302	double-strand break repair	3.80e-02	1.00e+00	4.692	1	3	62
GO:0010468	regulation of gene expression	4.17e-02	1.00e+00	4.559	1	2	68
GO:0008021	synaptic vesicle	4.47e-02	1.00e+00	4.456	1	2	73
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	4.53e-02	1.00e+00	4.437	1	4	74
GO:0002020	protease binding	4.53e-02	1.00e+00	4.437	1	6	74
GO:0009653	anatomical structure morphogenesis	5.06e-02	1.00e+00	4.271	1	2	83
GO:0009952	anterior/posterior pattern specification	5.06e-02	1.00e+00	4.271	1	4	83
GO:0006464	cellular protein modification process	5.12e-02	1.00e+00	4.254	1	4	84
GO:0016363	nuclear matrix	5.54e-02	1.00e+00	4.138	1	6	91
GO:0005737	cytoplasm	5.81e-02	1.00e+00	1.089	5	124	3767
GO:0003700	sequence-specific DNA binding transcription factor activity	6.73e-02	1.00e+00	2.197	2	39	699
GO:0097190	apoptotic signaling pathway	6.84e-02	1.00e+00	3.826	1	3	113
GO:0006325	chromatin organization	7.13e-02	1.00e+00	3.764	1	12	118
GO:0006260	DNA replication	7.30e-02	1.00e+00	3.727	1	3	121
GO:0006974	cellular response to DNA damage stimulus	9.04e-02	1.00e+00	3.408	1	7	151
GO:0007049	cell cycle	1.04e-01	1.00e+00	3.203	1	6	174
GO:0031625	ubiquitin protein ligase binding	1.06e-01	1.00e+00	3.170	1	5	178
GO:0003714	transcription corepressor activity	1.06e-01	1.00e+00	3.170	1	11	178
GO:0003713	transcription coactivator activity	1.39e-01	1.00e+00	2.757	1	24	237
GO:0008134	transcription factor binding	1.41e-01	1.00e+00	2.727	1	18	242
GO:0005654	nucleoplasm	1.42e-01	1.00e+00	1.567	2	64	1082
GO:0007283	spermatogenesis	1.52e-01	1.00e+00	2.613	1	3	262
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.53e-01	1.00e+00	2.602	1	23	264
GO:0043065	positive regulation of apoptotic process	1.55e-01	1.00e+00	2.580	1	7	268
GO:0006954	inflammatory response	1.60e-01	1.00e+00	2.532	1	6	277
GO:0030154	cell differentiation	1.73e-01	1.00e+00	2.413	1	5	301
GO:0019901	protein kinase binding	1.81e-01	1.00e+00	2.338	1	18	317
GO:0030054	cell junction	1.91e-01	1.00e+00	2.254	1	5	336
GO:0003723	RNA binding	1.94e-01	1.00e+00	2.228	1	18	342
GO:0043565	sequence-specific DNA binding	1.96e-01	1.00e+00	2.212	1	11	346
GO:0046982	protein heterodimerization activity	2.14e-01	1.00e+00	2.076	1	8	380
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.04e-01	1.00e+00	1.491	1	37	570
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.97e-01	1.00e+00	1.022	1	41	789
GO:0008270	zinc ion binding	4.75e-01	1.00e+00	0.685	1	27	997
GO:0044822	poly(A) RNA binding	4.96e-01	1.00e+00	0.602	1	50	1056
GO:0070062	extracellular vesicular exosome	8.06e-01	1.00e+00	-0.583	1	57	2400
GO:0005829	cytosol	8.19e-01	1.00e+00	-0.639	1	86	2496

chia-Fav

int-snw-79913

Statistics

Genes (9)

Interactions (18)

Related GO terms (90)