int-snw-6280

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.913	2.33e-16	1.84e-04	1.71e-03

chia-screen-data-Fav-int-snw-6280 subnetwork

Genes (15)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
TPR	7175	18	-2.638	3.072	28	Yes	Yes
LARS	51520	14	-2.574	3.157	105	Yes	Yes
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
PXN	5829	19	-2.554	3.193	206	Yes	Yes
CDC42	998	9	-2.199	3.119	265	Yes	Yes
TBC1D10A	83874	8	-2.544	2.989	26	Yes	-
ZNF43	7594	4	-2.555	2.923	1	Yes	Yes
PHB	5245	15	-2.743	3.004	127	Yes	Yes
ODF2	4957	4	-2.568	2.923	3	Yes	Yes
YAP1	10413	94	-4.256	3.538	53	Yes	-
APC	324	13	-2.293	3.004	353	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
[ S100A9 ]	6280	1	-1.759	2.913	43	-	-
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes

Interactions (14)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DDIT3	1649	S100A9	6280	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
PSMD2	5708	LARS	51520	pp	--	int.I2D: BioGrid_Yeast
APC	324	ZNF43	7594	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
APC	324	ODF2	4957	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
CDC42	998	TBC1D10A	83874	pp	--	int.I2D: BioGrid_Yeast
APC	324	TPR	7175	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct, SOURAV_MAPK_HIGH
APC	324	S100A9	6280	pp	--	int.I2D: Jorgensen_EphR
APC	324	PXN	5829	pp	--	int.I2D: MINT, MINT_Mouse; int.Mint: MI:0914(association)
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
APC	324	PHB	5245	pp	--	int.I2D: Jorgensen_EphR
CDC42	998	S100A9	6280	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct, SOURAV_MAPK_HIGH
APC	324	LARS	51520	pp	--	int.I2D: Jorgensen_EphR
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW

Related GO terms (396)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	2.11e-05	3.05e-01	8.102	2	2	7
GO:0044212	transcription regulatory region DNA binding	2.19e-05	3.16e-01	4.517	4	17	168
GO:0005515	protein binding	4.46e-05	6.44e-01	1.160	14	198	6024
GO:0031274	positive regulation of pseudopodium assembly	4.52e-05	6.52e-01	7.587	2	2	10
GO:0005654	nucleoplasm	4.94e-05	7.12e-01	2.637	7	64	1082
GO:0042789	mRNA transcription from RNA polymerase II promoter	7.82e-05	1.00e+00	7.209	2	2	13
GO:0042176	regulation of protein catabolic process	1.20e-04	1.00e+00	6.909	2	2	16
GO:0090316	positive regulation of intracellular protein transport	1.36e-04	1.00e+00	6.822	2	2	17
GO:0005634	nucleus	1.60e-04	1.00e+00	1.340	12	159	4559
GO:0036464	cytoplasmic ribonucleoprotein granule	2.30e-04	1.00e+00	6.450	2	2	22
GO:0005829	cytosol	2.51e-04	1.00e+00	1.794	9	86	2496
GO:1902017	regulation of cilium assembly	2.75e-04	1.00e+00	6.324	2	2	24
GO:0072686	mitotic spindle	4.03e-04	1.00e+00	6.051	2	3	29
GO:0031647	regulation of protein stability	4.32e-04	1.00e+00	6.002	2	4	30
GO:0007094	mitotic spindle assembly checkpoint	4.61e-04	1.00e+00	5.955	2	3	31
GO:0006974	cellular response to DNA damage stimulus	4.67e-04	1.00e+00	4.256	3	7	151
GO:0035019	somatic stem cell maintenance	7.70e-04	1.00e+00	5.587	2	6	40
GO:0043525	positive regulation of neuron apoptotic process	1.02e-03	1.00e+00	5.386	2	4	46
GO:1901673	regulation of spindle assembly involved in mitosis	1.04e-03	1.00e+00	9.909	1	1	1
GO:0043578	nuclear matrix organization	1.04e-03	1.00e+00	9.909	1	1	1
GO:2000016	negative regulation of determination of dorsal identity	1.04e-03	1.00e+00	9.909	1	1	1
GO:0010965	regulation of mitotic sister chromatid separation	1.04e-03	1.00e+00	9.909	1	1	1
GO:0051435	BH4 domain binding	1.04e-03	1.00e+00	9.909	1	1	1
GO:0006404	RNA import into nucleus	1.04e-03	1.00e+00	9.909	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	1.04e-03	1.00e+00	9.909	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	1.04e-03	1.00e+00	9.909	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	1.04e-03	1.00e+00	9.909	1	1	1
GO:0042483	negative regulation of odontogenesis	1.04e-03	1.00e+00	9.909	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	1.04e-03	1.00e+00	9.909	1	1	1
GO:0051171	regulation of nitrogen compound metabolic process	1.04e-03	1.00e+00	9.909	1	1	1
GO:0045113	regulation of integrin biosynthetic process	1.04e-03	1.00e+00	9.909	1	1	1
GO:0031453	positive regulation of heterochromatin assembly	1.04e-03	1.00e+00	9.909	1	1	1
GO:0008013	beta-catenin binding	1.73e-03	1.00e+00	5.002	2	9	60
GO:0000776	kinetochore	1.90e-03	1.00e+00	4.932	2	5	63
GO:0006429	leucyl-tRNA aminoacylation	2.08e-03	1.00e+00	8.909	1	1	2
GO:0071338	positive regulation of hair follicle cell proliferation	2.08e-03	1.00e+00	8.909	1	1	2
GO:0060242	contact inhibition	2.08e-03	1.00e+00	8.909	1	1	2
GO:0031990	mRNA export from nucleus in response to heat stress	2.08e-03	1.00e+00	8.909	1	2	2
GO:0032602	chemokine production	2.08e-03	1.00e+00	8.909	1	1	2
GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	2.08e-03	1.00e+00	8.909	1	1	2
GO:0070488	neutrophil aggregation	2.08e-03	1.00e+00	8.909	1	1	2
GO:0009786	regulation of asymmetric cell division	2.08e-03	1.00e+00	8.909	1	1	2
GO:0070840	dynein complex binding	2.08e-03	1.00e+00	8.909	1	1	2
GO:0060661	submandibular salivary gland formation	2.08e-03	1.00e+00	8.909	1	1	2
GO:0046832	negative regulation of RNA export from nucleus	2.08e-03	1.00e+00	8.909	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	2.08e-03	1.00e+00	8.909	1	1	2
GO:0000189	MAPK import into nucleus	2.08e-03	1.00e+00	8.909	1	1	2
GO:0090135	actin filament branching	2.08e-03	1.00e+00	8.909	1	1	2
GO:0004823	leucine-tRNA ligase activity	2.08e-03	1.00e+00	8.909	1	1	2
GO:0009798	axis specification	2.08e-03	1.00e+00	8.909	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	2.08e-03	1.00e+00	8.909	1	1	2
GO:0006355	regulation of transcription, DNA-templated	2.61e-03	1.00e+00	2.270	5	43	997
GO:0060070	canonical Wnt signaling pathway	2.68e-03	1.00e+00	4.680	2	4	75
GO:0051683	establishment of Golgi localization	3.12e-03	1.00e+00	8.324	1	1	3
GO:0034191	apolipoprotein A-I receptor binding	3.12e-03	1.00e+00	8.324	1	1	3
GO:0042306	regulation of protein import into nucleus	3.12e-03	1.00e+00	8.324	1	2	3
GO:0060913	cardiac cell fate determination	3.12e-03	1.00e+00	8.324	1	1	3
GO:0003161	cardiac conduction system development	3.12e-03	1.00e+00	8.324	1	1	3
GO:0006405	RNA export from nucleus	3.12e-03	1.00e+00	8.324	1	2	3
GO:0003130	BMP signaling pathway involved in heart induction	3.12e-03	1.00e+00	8.324	1	1	3
GO:0032119	sequestering of zinc ion	3.12e-03	1.00e+00	8.324	1	1	3
GO:0090090	negative regulation of canonical Wnt signaling pathway	3.51e-03	1.00e+00	4.483	2	8	86
GO:0019901	protein kinase binding	3.93e-03	1.00e+00	3.186	3	18	317
GO:0001649	osteoblast differentiation	4.00e-03	1.00e+00	4.386	2	5	92
GO:0035662	Toll-like receptor 4 binding	4.15e-03	1.00e+00	7.909	1	1	4
GO:0048664	neuron fate determination	4.15e-03	1.00e+00	7.909	1	1	4
GO:0060684	epithelial-mesenchymal cell signaling	4.15e-03	1.00e+00	7.909	1	1	4
GO:0051835	positive regulation of synapse structural plasticity	4.15e-03	1.00e+00	7.909	1	1	4
GO:0006999	nuclear pore organization	4.15e-03	1.00e+00	7.909	1	1	4
GO:0072384	organelle transport along microtubule	4.15e-03	1.00e+00	7.909	1	1	4
GO:0044615	nuclear pore nuclear basket	4.15e-03	1.00e+00	7.909	1	1	4
GO:0019887	protein kinase regulator activity	4.15e-03	1.00e+00	7.909	1	1	4
GO:0010467	gene expression	4.16e-03	1.00e+00	2.523	4	45	669
GO:0001714	endodermal cell fate specification	5.19e-03	1.00e+00	7.587	1	1	5
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	5.19e-03	1.00e+00	7.587	1	1	5
GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	5.19e-03	1.00e+00	7.587	1	2	5
GO:0043620	regulation of DNA-templated transcription in response to stress	5.19e-03	1.00e+00	7.587	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	5.19e-03	1.00e+00	7.587	1	2	5
GO:0036336	dendritic cell migration	5.19e-03	1.00e+00	7.587	1	1	5
GO:0035088	establishment or maintenance of apical/basal cell polarity	5.19e-03	1.00e+00	7.587	1	1	5
GO:0050544	arachidonic acid binding	5.19e-03	1.00e+00	7.587	1	1	5
GO:0031256	leading edge membrane	5.19e-03	1.00e+00	7.587	1	1	5
GO:0010793	regulation of mRNA export from nucleus	5.19e-03	1.00e+00	7.587	1	1	5
GO:0070849	response to epidermal growth factor	5.19e-03	1.00e+00	7.587	1	1	5
GO:0030858	positive regulation of epithelial cell differentiation	6.22e-03	1.00e+00	7.324	1	1	6
GO:0007097	nuclear migration	6.22e-03	1.00e+00	7.324	1	1	6
GO:0050847	progesterone receptor signaling pathway	6.22e-03	1.00e+00	7.324	1	2	6
GO:0003334	keratinocyte development	6.22e-03	1.00e+00	7.324	1	1	6
GO:0001520	outer dense fiber	6.22e-03	1.00e+00	7.324	1	1	6
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.22e-03	1.00e+00	7.324	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	6.22e-03	1.00e+00	7.324	1	3	6
GO:0060789	hair follicle placode formation	6.22e-03	1.00e+00	7.324	1	2	6
GO:0048554	positive regulation of metalloenzyme activity	6.22e-03	1.00e+00	7.324	1	1	6
GO:0043497	regulation of protein heterodimerization activity	6.22e-03	1.00e+00	7.324	1	1	6
GO:0000278	mitotic cell cycle	7.06e-03	1.00e+00	2.883	3	15	391
GO:0007050	cell cycle arrest	7.16e-03	1.00e+00	3.955	2	5	124
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	7.26e-03	1.00e+00	7.102	1	2	7
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	7.26e-03	1.00e+00	7.102	1	1	7
GO:0046825	regulation of protein export from nucleus	7.26e-03	1.00e+00	7.102	1	2	7
GO:0071354	cellular response to interleukin-6	7.26e-03	1.00e+00	7.102	1	2	7
GO:0002161	aminoacyl-tRNA editing activity	7.26e-03	1.00e+00	7.102	1	2	7
GO:0051489	regulation of filopodium assembly	7.26e-03	1.00e+00	7.102	1	1	7
GO:0030027	lamellipodium	7.27e-03	1.00e+00	3.943	2	7	125
GO:0097202	activation of cysteine-type endopeptidase activity	8.29e-03	1.00e+00	6.909	1	1	8
GO:0045670	regulation of osteoclast differentiation	8.29e-03	1.00e+00	6.909	1	2	8
GO:0051292	nuclear pore complex assembly	8.29e-03	1.00e+00	6.909	1	4	8
GO:0001955	blood vessel maturation	8.29e-03	1.00e+00	6.909	1	1	8
GO:0035457	cellular response to interferon-alpha	8.29e-03	1.00e+00	6.909	1	1	8
GO:0002523	leukocyte migration involved in inflammatory response	8.29e-03	1.00e+00	6.909	1	1	8
GO:0007172	signal complex assembly	8.29e-03	1.00e+00	6.909	1	1	8
GO:0060396	growth hormone receptor signaling pathway	8.29e-03	1.00e+00	6.909	1	1	8
GO:0002544	chronic inflammatory response	9.32e-03	1.00e+00	6.739	1	1	9
GO:0045667	regulation of osteoblast differentiation	9.32e-03	1.00e+00	6.739	1	1	9
GO:0042405	nuclear inclusion body	9.32e-03	1.00e+00	6.739	1	2	9
GO:0006450	regulation of translational fidelity	9.32e-03	1.00e+00	6.739	1	2	9
GO:0090136	epithelial cell-cell adhesion	9.32e-03	1.00e+00	6.739	1	1	9
GO:0006983	ER overload response	9.32e-03	1.00e+00	6.739	1	1	9
GO:0043495	protein anchor	9.32e-03	1.00e+00	6.739	1	1	9
GO:0010944	negative regulation of transcription by competitive promoter binding	9.32e-03	1.00e+00	6.739	1	1	9
GO:0008017	microtubule binding	9.93e-03	1.00e+00	3.710	2	2	147
GO:0042981	regulation of apoptotic process	1.03e-02	1.00e+00	3.680	2	4	150
GO:0035413	positive regulation of catenin import into nucleus	1.04e-02	1.00e+00	6.587	1	2	10
GO:0030877	beta-catenin destruction complex	1.04e-02	1.00e+00	6.587	1	2	10
GO:0060047	heart contraction	1.04e-02	1.00e+00	6.587	1	1	10
GO:0051010	microtubule plus-end binding	1.14e-02	1.00e+00	6.450	1	1	11
GO:0045662	negative regulation of myoblast differentiation	1.14e-02	1.00e+00	6.450	1	3	11
GO:0017166	vinculin binding	1.14e-02	1.00e+00	6.450	1	1	11
GO:0031116	positive regulation of microtubule polymerization	1.14e-02	1.00e+00	6.450	1	1	11
GO:0050786	RAGE receptor binding	1.14e-02	1.00e+00	6.450	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	1.14e-02	1.00e+00	6.450	1	4	11
GO:0032886	regulation of microtubule-based process	1.24e-02	1.00e+00	6.324	1	1	12
GO:0045947	negative regulation of translational initiation	1.24e-02	1.00e+00	6.324	1	2	12
GO:0045295	gamma-catenin binding	1.24e-02	1.00e+00	6.324	1	1	12
GO:0034399	nuclear periphery	1.24e-02	1.00e+00	6.324	1	5	12
GO:0005838	proteasome regulatory particle	1.24e-02	1.00e+00	6.324	1	1	12
GO:0035198	miRNA binding	1.24e-02	1.00e+00	6.324	1	1	12
GO:0071480	cellular response to gamma radiation	1.34e-02	1.00e+00	6.209	1	1	13
GO:0060766	negative regulation of androgen receptor signaling pathway	1.34e-02	1.00e+00	6.209	1	3	13
GO:0044295	axonal growth cone	1.34e-02	1.00e+00	6.209	1	1	13
GO:0051019	mitogen-activated protein kinase binding	1.34e-02	1.00e+00	6.209	1	2	13
GO:0043409	negative regulation of MAPK cascade	1.34e-02	1.00e+00	6.209	1	2	13
GO:0005868	cytoplasmic dynein complex	1.34e-02	1.00e+00	6.209	1	1	13
GO:0030234	enzyme regulator activity	1.34e-02	1.00e+00	6.209	1	2	13
GO:0046827	positive regulation of protein export from nucleus	1.34e-02	1.00e+00	6.209	1	1	13
GO:0003714	transcription corepressor activity	1.43e-02	1.00e+00	3.433	2	11	178
GO:0035371	microtubule plus-end	1.45e-02	1.00e+00	6.102	1	1	14
GO:0031333	negative regulation of protein complex assembly	1.45e-02	1.00e+00	6.102	1	1	14
GO:0016209	antioxidant activity	1.45e-02	1.00e+00	6.102	1	2	14
GO:0031996	thioesterase binding	1.45e-02	1.00e+00	6.102	1	1	14
GO:0034614	cellular response to reactive oxygen species	1.45e-02	1.00e+00	6.102	1	2	14
GO:0005487	nucleocytoplasmic transporter activity	1.45e-02	1.00e+00	6.102	1	3	14
GO:0042307	positive regulation of protein import into nucleus	1.55e-02	1.00e+00	6.002	1	4	15
GO:0030225	macrophage differentiation	1.55e-02	1.00e+00	6.002	1	2	15
GO:0050832	defense response to fungus	1.55e-02	1.00e+00	6.002	1	1	15
GO:0001824	blastocyst development	1.55e-02	1.00e+00	6.002	1	2	15
GO:0051233	spindle midzone	1.55e-02	1.00e+00	6.002	1	2	15
GO:0007173	epidermal growth factor receptor signaling pathway	1.60e-02	1.00e+00	3.347	2	5	189
GO:0051493	regulation of cytoskeleton organization	1.65e-02	1.00e+00	5.909	1	1	16
GO:0007026	negative regulation of microtubule depolymerization	1.65e-02	1.00e+00	5.909	1	1	16
GO:0046716	muscle cell cellular homeostasis	1.65e-02	1.00e+00	5.909	1	1	16
GO:0051276	chromosome organization	1.65e-02	1.00e+00	5.909	1	2	16
GO:0030742	GTP-dependent protein binding	1.75e-02	1.00e+00	5.822	1	1	17
GO:0022624	proteasome accessory complex	1.75e-02	1.00e+00	5.822	1	1	17
GO:0031122	cytoplasmic microtubule organization	1.86e-02	1.00e+00	5.739	1	1	18
GO:0007088	regulation of mitosis	1.86e-02	1.00e+00	5.739	1	1	18
GO:0046847	filopodium assembly	1.96e-02	1.00e+00	5.661	1	1	19
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	1.96e-02	1.00e+00	5.661	1	2	19
GO:0032757	positive regulation of interleukin-8 production	2.06e-02	1.00e+00	5.587	1	1	20
GO:0031435	mitogen-activated protein kinase kinase kinase binding	2.16e-02	1.00e+00	5.517	1	1	21
GO:0045862	positive regulation of proteolysis	2.16e-02	1.00e+00	5.517	1	2	21
GO:0048041	focal adhesion assembly	2.16e-02	1.00e+00	5.517	1	1	21
GO:0009954	proximal/distal pattern formation	2.16e-02	1.00e+00	5.517	1	1	21
GO:0016575	histone deacetylation	2.16e-02	1.00e+00	5.517	1	3	21
GO:0000281	mitotic cytokinesis	2.16e-02	1.00e+00	5.517	1	2	21
GO:0005737	cytoplasm	2.24e-02	1.00e+00	1.030	8	124	3767
GO:0031424	keratinization	2.26e-02	1.00e+00	5.450	1	1	22
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	2.37e-02	1.00e+00	5.386	1	3	23
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	2.37e-02	1.00e+00	5.386	1	1	23
GO:0002040	sprouting angiogenesis	2.37e-02	1.00e+00	5.386	1	2	23
GO:0051017	actin filament bundle assembly	2.37e-02	1.00e+00	5.386	1	1	23
GO:0007163	establishment or maintenance of cell polarity	2.47e-02	1.00e+00	5.324	1	2	24
GO:0010043	response to zinc ion	2.47e-02	1.00e+00	5.324	1	1	24
GO:0045296	cadherin binding	2.47e-02	1.00e+00	5.324	1	3	24
GO:0008134	transcription factor binding	2.55e-02	1.00e+00	2.990	2	18	242
GO:0006611	protein export from nucleus	2.57e-02	1.00e+00	5.265	1	3	25
GO:0001816	cytokine production	2.57e-02	1.00e+00	5.265	1	1	25
GO:0035329	hippo signaling	2.67e-02	1.00e+00	5.209	1	5	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	2.67e-02	1.00e+00	5.209	1	3	26
GO:0051209	release of sequestered calcium ion into cytosol	2.67e-02	1.00e+00	5.209	1	1	26
GO:0045859	regulation of protein kinase activity	2.67e-02	1.00e+00	5.209	1	1	26
GO:0072372	primary cilium	2.67e-02	1.00e+00	5.209	1	1	26
GO:0048754	branching morphogenesis of an epithelial tube	2.77e-02	1.00e+00	5.154	1	1	27
GO:0015631	tubulin binding	2.77e-02	1.00e+00	5.154	1	2	27
GO:0051149	positive regulation of muscle cell differentiation	2.77e-02	1.00e+00	5.154	1	4	27
GO:0032467	positive regulation of cytokinesis	2.77e-02	1.00e+00	5.154	1	2	27
GO:0031069	hair follicle morphogenesis	2.77e-02	1.00e+00	5.154	1	1	27
GO:0005875	microtubule associated complex	2.87e-02	1.00e+00	5.102	1	1	28
GO:0034605	cellular response to heat	2.87e-02	1.00e+00	5.102	1	1	28
GO:0071897	DNA biosynthetic process	2.87e-02	1.00e+00	5.102	1	1	28
GO:0070830	tight junction assembly	2.87e-02	1.00e+00	5.102	1	1	28
GO:0005913	cell-cell adherens junction	2.98e-02	1.00e+00	5.051	1	3	29
GO:0030032	lamellipodium assembly	2.98e-02	1.00e+00	5.051	1	1	29
GO:0006606	protein import into nucleus	3.08e-02	1.00e+00	5.002	1	2	30
GO:0010827	regulation of glucose transport	3.08e-02	1.00e+00	5.002	1	4	30
GO:0009953	dorsal/ventral pattern formation	3.18e-02	1.00e+00	4.955	1	2	31
GO:0042594	response to starvation	3.18e-02	1.00e+00	4.955	1	4	31
GO:0003677	DNA binding	3.25e-02	1.00e+00	1.659	4	49	1218
GO:1903507	negative regulation of nucleic acid-templated transcription	3.28e-02	1.00e+00	4.909	1	2	32
GO:0003700	sequence-specific DNA binding transcription factor activity	3.33e-02	1.00e+00	2.045	3	39	699
GO:0033077	T cell differentiation in thymus	3.38e-02	1.00e+00	4.865	1	1	33
GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	3.38e-02	1.00e+00	4.865	1	1	33
GO:0031072	heat shock protein binding	3.38e-02	1.00e+00	4.865	1	2	33
GO:0005097	Rab GTPase activator activity	3.48e-02	1.00e+00	4.822	1	1	34
GO:0042692	muscle cell differentiation	3.48e-02	1.00e+00	4.822	1	4	34
GO:0001942	hair follicle development	3.58e-02	1.00e+00	4.780	1	2	35
GO:0034332	adherens junction organization	3.68e-02	1.00e+00	4.739	1	2	36
GO:0007077	mitotic nuclear envelope disassembly	3.68e-02	1.00e+00	4.739	1	4	36
GO:0034446	substrate adhesion-dependent cell spreading	3.68e-02	1.00e+00	4.739	1	2	36
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	3.68e-02	1.00e+00	4.739	1	2	36
GO:0045740	positive regulation of DNA replication	3.68e-02	1.00e+00	4.739	1	1	36
GO:0048538	thymus development	3.68e-02	1.00e+00	4.739	1	2	36
GO:0005902	microvillus	3.88e-02	1.00e+00	4.661	1	3	38
GO:0008645	hexose transport	3.98e-02	1.00e+00	4.624	1	4	39
GO:0051781	positive regulation of cell division	3.98e-02	1.00e+00	4.624	1	1	39
GO:0005881	cytoplasmic microtubule	4.08e-02	1.00e+00	4.587	1	1	40
GO:0045785	positive regulation of cell adhesion	4.08e-02	1.00e+00	4.587	1	2	40
GO:0007286	spermatid development	4.18e-02	1.00e+00	4.552	1	1	41
GO:0031532	actin cytoskeleton reorganization	4.18e-02	1.00e+00	4.552	1	2	41
GO:0042147	retrograde transport, endosome to Golgi	4.18e-02	1.00e+00	4.552	1	1	41
GO:0030593	neutrophil chemotaxis	4.18e-02	1.00e+00	4.552	1	2	41
GO:0006418	tRNA aminoacylation for protein translation	4.28e-02	1.00e+00	4.517	1	3	42
GO:0019898	extrinsic component of membrane	4.28e-02	1.00e+00	4.517	1	2	42
GO:0005813	centrosome	4.41e-02	1.00e+00	2.560	2	7	326
GO:0021762	substantia nigra development	4.48e-02	1.00e+00	4.450	1	4	44
GO:0034613	cellular protein localization	4.48e-02	1.00e+00	4.450	1	2	44
GO:0016328	lateral plasma membrane	4.68e-02	1.00e+00	4.386	1	3	46
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	4.78e-02	1.00e+00	4.355	1	2	47
GO:0050729	positive regulation of inflammatory response	4.88e-02	1.00e+00	4.324	1	2	48
GO:0043565	sequence-specific DNA binding	4.90e-02	1.00e+00	2.475	2	11	346
GO:0007030	Golgi organization	4.98e-02	1.00e+00	4.294	1	3	49
GO:0006521	regulation of cellular amino acid metabolic process	5.08e-02	1.00e+00	4.265	1	1	50
GO:0006986	response to unfolded protein	5.08e-02	1.00e+00	4.265	1	4	50
GO:0008285	negative regulation of cell proliferation	5.08e-02	1.00e+00	2.446	2	10	353
GO:0030175	filopodium	5.08e-02	1.00e+00	4.265	1	1	50
GO:0045732	positive regulation of protein catabolic process	5.08e-02	1.00e+00	4.265	1	1	50
GO:0060041	retina development in camera-type eye	5.18e-02	1.00e+00	4.237	1	2	51
GO:0034976	response to endoplasmic reticulum stress	5.18e-02	1.00e+00	4.237	1	2	51
GO:0045454	cell redox homeostasis	5.18e-02	1.00e+00	4.237	1	1	51
GO:0009611	response to wounding	5.28e-02	1.00e+00	4.209	1	5	52
GO:0032851	positive regulation of Rab GTPase activity	5.38e-02	1.00e+00	4.181	1	2	53
GO:0005925	focal adhesion	5.42e-02	1.00e+00	2.393	2	9	366
GO:0007155	cell adhesion	5.50e-02	1.00e+00	2.382	2	5	369
GO:0015758	glucose transport	5.57e-02	1.00e+00	4.128	1	4	55
GO:0001725	stress fiber	5.57e-02	1.00e+00	4.128	1	4	55
GO:0046330	positive regulation of JNK cascade	5.57e-02	1.00e+00	4.128	1	2	55
GO:0036064	ciliary basal body	5.77e-02	1.00e+00	4.076	1	2	57
GO:0005643	nuclear pore	5.77e-02	1.00e+00	4.076	1	11	57
GO:0000502	proteasome complex	5.87e-02	1.00e+00	4.051	1	3	58
GO:0033138	positive regulation of peptidyl-serine phosphorylation	5.97e-02	1.00e+00	4.027	1	2	59
GO:0006396	RNA processing	5.97e-02	1.00e+00	4.027	1	5	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	5.97e-02	1.00e+00	4.027	1	6	59
GO:0042742	defense response to bacterium	6.06e-02	1.00e+00	4.002	1	5	60
GO:0006987	activation of signaling protein activity involved in unfolded protein response	6.16e-02	1.00e+00	3.978	1	2	61
GO:0030141	secretory granule	6.26e-02	1.00e+00	3.955	1	4	62
GO:0007165	signal transduction	6.40e-02	1.00e+00	1.669	3	13	907
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	6.46e-02	1.00e+00	3.909	1	1	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.55e-02	1.00e+00	3.887	1	2	65
GO:0031295	T cell costimulation	6.55e-02	1.00e+00	3.887	1	1	65
GO:0007409	axonogenesis	6.55e-02	1.00e+00	3.887	1	2	65
GO:0045892	negative regulation of transcription, DNA-templated	6.72e-02	1.00e+00	2.219	2	24	413
GO:0035264	multicellular organism growth	6.75e-02	1.00e+00	3.843	1	2	67
GO:0010468	regulation of gene expression	6.85e-02	1.00e+00	3.822	1	2	68
GO:0034329	cell junction assembly	6.85e-02	1.00e+00	3.822	1	3	68
GO:0030307	positive regulation of cell growth	6.94e-02	1.00e+00	3.801	1	2	69
GO:0032587	ruffle membrane	7.04e-02	1.00e+00	3.780	1	3	70
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.04e-02	1.00e+00	3.780	1	2	70
GO:0005085	guanyl-nucleotide exchange factor activity	7.14e-02	1.00e+00	3.759	1	5	71
GO:0042826	histone deacetylase binding	7.24e-02	1.00e+00	3.739	1	4	72
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	7.24e-02	1.00e+00	3.739	1	1	72
GO:0003729	mRNA binding	7.24e-02	1.00e+00	3.739	1	4	72
GO:0006914	autophagy	7.43e-02	1.00e+00	3.700	1	3	74
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	7.43e-02	1.00e+00	3.700	1	2	74
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	7.43e-02	1.00e+00	3.700	1	4	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.43e-02	1.00e+00	3.700	1	2	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	7.53e-02	1.00e+00	3.680	1	1	75
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	7.53e-02	1.00e+00	3.680	1	1	75
GO:0017137	Rab GTPase binding	7.62e-02	1.00e+00	3.661	1	1	76
GO:0010629	negative regulation of gene expression	7.72e-02	1.00e+00	3.642	1	4	77
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	7.72e-02	1.00e+00	3.642	1	3	77
GO:0001822	kidney development	7.82e-02	1.00e+00	3.624	1	3	78
GO:0007229	integrin-mediated signaling pathway	7.82e-02	1.00e+00	3.624	1	3	78
GO:0071013	catalytic step 2 spliceosome	7.82e-02	1.00e+00	3.624	1	7	78
GO:0030968	endoplasmic reticulum unfolded protein response	7.91e-02	1.00e+00	3.605	1	2	79
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	7.91e-02	1.00e+00	3.605	1	2	79
GO:0005814	centriole	7.91e-02	1.00e+00	3.605	1	2	79
GO:0045177	apical part of cell	8.10e-02	1.00e+00	3.569	1	3	81
GO:0009653	anatomical structure morphogenesis	8.30e-02	1.00e+00	3.534	1	2	83
GO:0009952	anterior/posterior pattern specification	8.30e-02	1.00e+00	3.534	1	4	83
GO:0005923	tight junction	8.58e-02	1.00e+00	3.483	1	2	86
GO:0045471	response to ethanol	8.58e-02	1.00e+00	3.483	1	3	86
GO:0045893	positive regulation of transcription, DNA-templated	8.66e-02	1.00e+00	2.008	2	24	478
GO:0000922	spindle pole	8.68e-02	1.00e+00	3.466	1	4	87
GO:0006936	muscle contraction	8.68e-02	1.00e+00	3.466	1	3	87
GO:0016020	membrane	8.80e-02	1.00e+00	1.194	4	46	1681
GO:0070062	extracellular vesicular exosome	8.92e-02	1.00e+00	1.002	5	57	2400
GO:0000187	activation of MAPK activity	8.97e-02	1.00e+00	3.417	1	3	90
GO:0007010	cytoskeleton organization	9.06e-02	1.00e+00	3.401	1	4	91
GO:0006928	cellular component movement	9.06e-02	1.00e+00	3.401	1	3	91
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	9.16e-02	1.00e+00	3.386	1	1	92
GO:0044822	poly(A) RNA binding	9.20e-02	1.00e+00	1.450	3	50	1056
GO:0005770	late endosome	9.25e-02	1.00e+00	3.370	1	2	93
GO:0030165	PDZ domain binding	9.35e-02	1.00e+00	3.355	1	1	94
GO:0005178	integrin binding	9.54e-02	1.00e+00	3.324	1	4	96
GO:0008360	regulation of cell shape	1.02e-01	1.00e+00	3.223	1	4	103
GO:0005938	cell cortex	1.03e-01	1.00e+00	3.209	1	5	104
GO:0016032	viral process	1.05e-01	1.00e+00	1.848	2	26	534
GO:0030496	midbody	1.07e-01	1.00e+00	3.154	1	2	108
GO:0005815	microtubule organizing center	1.08e-01	1.00e+00	3.141	1	3	109
GO:0006461	protein complex assembly	1.09e-01	1.00e+00	3.115	1	4	111
GO:0030308	negative regulation of cell growth	1.09e-01	1.00e+00	3.128	1	6	110
GO:0030529	ribonucleoprotein complex	1.10e-01	1.00e+00	3.102	1	5	112
GO:0005635	nuclear envelope	1.11e-01	1.00e+00	3.089	1	5	113
GO:0006915	apoptotic process	1.12e-01	1.00e+00	1.793	2	12	555
GO:0051056	regulation of small GTPase mediated signal transduction	1.13e-01	1.00e+00	3.064	1	3	115
GO:0005886	plasma membrane	1.14e-01	1.00e+00	0.897	5	49	2582
GO:0000209	protein polyubiquitination	1.14e-01	1.00e+00	3.051	1	3	116
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.17e-01	1.00e+00	1.754	2	37	570
GO:0032496	response to lipopolysaccharide	1.19e-01	1.00e+00	2.990	1	4	121
GO:0030036	actin cytoskeleton organization	1.21e-01	1.00e+00	2.967	1	3	123
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.22e-01	1.00e+00	2.955	1	5	124
GO:0030335	positive regulation of cell migration	1.24e-01	1.00e+00	2.921	1	5	127
GO:0007179	transforming growth factor beta receptor signaling pathway	1.25e-01	1.00e+00	2.909	1	11	128
GO:0016477	cell migration	1.25e-01	1.00e+00	2.909	1	4	128
GO:0045087	innate immune response	1.26e-01	1.00e+00	1.690	2	15	596
GO:0005215	transporter activity	1.27e-01	1.00e+00	2.887	1	3	130
GO:0018108	peptidyl-tyrosine phosphorylation	1.29e-01	1.00e+00	2.865	1	4	132
GO:0005911	cell-cell junction	1.33e-01	1.00e+00	2.822	1	2	136
GO:0000086	G2/M transition of mitotic cell cycle	1.33e-01	1.00e+00	2.822	1	4	136
GO:0016055	Wnt signaling pathway	1.34e-01	1.00e+00	2.801	1	4	138
GO:0010628	positive regulation of gene expression	1.42e-01	1.00e+00	2.719	1	7	146
GO:0000082	G1/S transition of mitotic cell cycle	1.44e-01	1.00e+00	2.690	1	3	149
GO:0005198	structural molecule activity	1.45e-01	1.00e+00	2.680	1	3	150
GO:0043005	neuron projection	1.51e-01	1.00e+00	2.615	1	3	157
GO:0000398	mRNA splicing, via spliceosome	1.58e-01	1.00e+00	2.552	1	15	164
GO:0031965	nuclear membrane	1.61e-01	1.00e+00	2.517	1	10	168
GO:0034641	cellular nitrogen compound metabolic process	1.64e-01	1.00e+00	2.491	1	2	171
GO:0005667	transcription factor complex	1.67e-01	1.00e+00	2.458	1	17	175
GO:0031625	ubiquitin protein ligase binding	1.70e-01	1.00e+00	2.433	1	5	178
GO:0006367	transcription initiation from RNA polymerase II promoter	1.75e-01	1.00e+00	2.386	1	22	184
GO:0003924	GTPase activity	1.86e-01	1.00e+00	2.287	1	7	197
GO:0004871	signal transducer activity	1.96e-01	1.00e+00	2.209	1	4	208
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.97e-01	1.00e+00	1.285	2	41	789
GO:0006184	GTP catabolic process	2.01e-01	1.00e+00	2.168	1	7	214
GO:0007267	cell-cell signaling	2.05e-01	1.00e+00	2.134	1	2	219
GO:0019221	cytokine-mediated signaling pathway	2.07e-01	1.00e+00	2.121	1	8	221
GO:0016071	mRNA metabolic process	2.09e-01	1.00e+00	2.108	1	8	223
GO:0007067	mitotic nuclear division	2.12e-01	1.00e+00	2.083	1	6	227
GO:0008380	RNA splicing	2.13e-01	1.00e+00	2.076	1	22	228
GO:0003713	transcription coactivator activity	2.20e-01	1.00e+00	2.020	1	24	237
GO:0043025	neuronal cell body	2.27e-01	1.00e+00	1.973	1	9	245
GO:0016070	RNA metabolic process	2.28e-01	1.00e+00	1.961	1	8	247
GO:0005874	microtubule	2.30e-01	1.00e+00	1.949	1	7	249
GO:0005975	carbohydrate metabolic process	2.33e-01	1.00e+00	1.926	1	8	253
GO:0043065	positive regulation of apoptotic process	2.45e-01	1.00e+00	1.843	1	7	268
GO:0005743	mitochondrial inner membrane	2.53e-01	1.00e+00	1.795	1	6	277
GO:0006954	inflammatory response	2.53e-01	1.00e+00	1.795	1	6	277
GO:0019899	enzyme binding	2.53e-01	1.00e+00	1.795	1	9	277
GO:0007264	small GTPase mediated signal transduction	2.54e-01	1.00e+00	1.785	1	3	279
GO:0005856	cytoskeleton	2.64e-01	1.00e+00	1.724	1	9	291
GO:0008270	zinc ion binding	2.78e-01	1.00e+00	0.948	2	27	997
GO:0005525	GTP binding	2.78e-01	1.00e+00	1.633	1	12	310
GO:0007275	multicellular organismal development	2.83e-01	1.00e+00	1.605	1	7	316
GO:0007411	axon guidance	2.85e-01	1.00e+00	1.592	1	5	319
GO:0003682	chromatin binding	2.91e-01	1.00e+00	1.556	1	19	327
GO:0008283	cell proliferation	2.92e-01	1.00e+00	1.552	1	14	328
GO:0003723	RNA binding	3.02e-01	1.00e+00	1.491	1	18	342
GO:0000139	Golgi membrane	3.16e-01	1.00e+00	1.413	1	7	361
GO:0046982	protein heterodimerization activity	3.30e-01	1.00e+00	1.339	1	8	380
GO:0009986	cell surface	3.46e-01	1.00e+00	1.258	1	9	402
GO:0006366	transcription from RNA polymerase II promoter	3.58e-01	1.00e+00	1.198	1	30	419
GO:0043066	negative regulation of apoptotic process	3.61e-01	1.00e+00	1.181	1	16	424
GO:0044281	small molecule metabolic process	3.63e-01	1.00e+00	0.667	2	20	1211
GO:0055085	transmembrane transport	3.68e-01	1.00e+00	1.144	1	8	435
GO:0007596	blood coagulation	3.82e-01	1.00e+00	1.079	1	11	455
GO:0044267	cellular protein metabolic process	3.94e-01	1.00e+00	1.020	1	20	474
GO:0005524	ATP binding	3.97e-01	1.00e+00	0.567	2	31	1298
GO:0042802	identical protein binding	4.01e-01	1.00e+00	0.990	1	19	484
GO:0005509	calcium ion binding	4.30e-01	1.00e+00	0.857	1	11	531
GO:0042803	protein homodimerization activity	4.69e-01	1.00e+00	0.692	1	19	595
GO:0005887	integral component of plasma membrane	6.15e-01	1.00e+00	0.115	1	10	888
GO:0005576	extracellular region	6.37e-01	1.00e+00	0.030	1	13	942
GO:0005615	extracellular space	6.43e-01	1.00e+00	0.007	1	20	957
GO:0005739	mitochondrion	6.59e-01	1.00e+00	-0.054	1	23	998
GO:0046872	metal ion binding	7.60e-01	1.00e+00	-0.443	1	29	1307
GO:0006351	transcription, DNA-templated	7.95e-01	1.00e+00	-0.589	1	57	1446
GO:0005730	nucleolus	8.37e-01	1.00e+00	-0.771	1	66	1641

chia-Fav

int-snw-6280

Statistics

Genes (15)

Interactions (14)

Related GO terms (396)