int-snw-3895

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.825 2.15e-15 5.49e-04 3.70e-03
chia-screen-data-Fav-int-snw-3895 subnetwork

Genes (17)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Chia-Hits Primary Chia-Hits Secondary
RHOA 387 5-2.4082.845151YesYes
ZC3H18 124245 3-2.4262.9376Yes-
YAP1 10413 94-4.2563.53853Yes-
POU5F1 5460 133-5.1483.538179YesYes
SON 6651 9-3.8443.1089YesYes
[ KTN1 ] 3895 1-1.2122.82518--
SUMO1 7341 7-1.6963.050439--
TPR 7175 18-2.6383.07228YesYes
APLP2 334 12-2.7323.20635YesYes
PSMD2 5708 47-4.1723.157386YesYes
CDC42 998 9-2.1993.119265YesYes
SHFM1 7979 2-2.3662.8476Yes-
TBC1D10A 83874 8-2.5442.98926Yes-
MED12 9968 14-2.4653.20665Yes-
HNRNPU 3192 76-2.8693.538139Yes-
ACSS1 84532 2-2.3262.842148Yes-
CDK12 51755 6-2.7142.94415Yes-

Interactions (20)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
HNRNPU 3192 SUMO1 7341 pp -- int.I2D: BioGrid
SON 6651 SUMO1 7341 pp -- int.I2D: BioGrid
APLP2 334 MED12 9968 pp -- int.I2D: MINT;
int.Mint: MI:0407(direct interaction)
SUMO1 7341 MED12 9968 pp -- int.I2D: BioGrid
RHOA 387 ACSS1 84532 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
HNRNPU 3192 POU5F1 5460 pp -- int.I2D: BioGrid_Mouse, IntAct_Mouse
SUMO1 7341 ZC3H18 124245 pp -- int.I2D: BioGrid
KTN1 3895 SUMO1 7341 pp -- int.I2D: BioGrid
PSMD2 5708 ACSS1 84532 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
SUMO1 7341 CDK12 51755 pp -- int.I2D: BioGrid
HNRNPU 3192 YAP1 10413 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
CDC42 998 SHFM1 7979 pp -- int.I2D: IntAct, SOURAV_MAPK_LOW
RHOA 387 TBC1D10A 83874 pp -- int.I2D: BioGrid_Yeast
RHOA 387 PSMD2 5708 pp -- int.I2D: BioGrid_Yeast
CDC42 998 TBC1D10A 83874 pp -- int.I2D: BioGrid_Yeast
RHOA 387 KTN1 3895 pp -- int.I2D: BioGrid, HPRD;
int.HPRD: in vitro, in vivo, yeast 2-hybrid
APLP2 334 RHOA 387 pp -- int.I2D: IntAct_Mouse
POU5F1 5460 SUMO1 7341 pp -- int.I2D: BioGrid, BioGrid_Mouse
CDC42 998 KTN1 3895 pp -- int.I2D: HPRD;
int.HPRD: in vitro, yeast 2-hybrid
TPR 7175 SUMO1 7341 pp -- int.I2D: BioGrid

Related GO terms (350)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005515protein binding1.03e-041.00e+001.079151986024
GO:0044822poly(A) RNA binding1.12e-041.00e+002.4927501056
GO:0005654nucleoplasm1.31e-041.00e+002.4567641082
GO:0042176regulation of protein catabolic process1.55e-041.00e+006.7292216
GO:0090316positive regulation of intracellular protein transport1.76e-041.00e+006.6412217
GO:0036464cytoplasmic ribonucleoprotein granule2.98e-041.00e+006.2692222
GO:0032467positive regulation of cytokinesis4.51e-041.00e+005.9742227
GO:0072686mitotic spindle5.21e-041.00e+005.8712329
GO:0031647regulation of protein stability5.58e-041.00e+005.8222430
GO:0016607nuclear speck1.00e-031.00e+003.887312172
GO:1901673regulation of spindle assembly involved in mitosis1.18e-031.00e+009.729111
GO:0043578nuclear matrix organization1.18e-031.00e+009.729111
GO:0010965regulation of mitotic sister chromatid separation1.18e-031.00e+009.729111
GO:0006404RNA import into nucleus1.18e-031.00e+009.729111
GO:0090308regulation of methylation-dependent chromatin silencing1.18e-031.00e+009.729111
GO:0090081regulation of heart induction by regulation of canonical Wnt signaling pathway1.18e-031.00e+009.729111
GO:0060965negative regulation of gene silencing by miRNA1.18e-031.00e+009.729111
GO:0060795cell fate commitment involved in formation of primary germ layer1.18e-031.00e+009.729111
GO:0061383trabecula morphogenesis1.18e-031.00e+009.729111
GO:0006085acetyl-CoA biosynthetic process1.18e-031.00e+009.729111
GO:0031453positive regulation of heterochromatin assembly1.18e-031.00e+009.729111
GO:0021762substantia nigra development1.20e-031.00e+005.2692444
GO:0005643nuclear pore2.01e-031.00e+004.89621157
GO:0000502proteasome complex2.08e-031.00e+004.8712358
GO:0008380RNA splicing2.25e-031.00e+003.481322228
GO:0071338positive regulation of hair follicle cell proliferation2.36e-031.00e+008.729112
GO:0060242contact inhibition2.36e-031.00e+008.729112
GO:0031990mRNA export from nucleus in response to heat stress2.36e-031.00e+008.729122
GO:0070816phosphorylation of RNA polymerase II C-terminal domain2.36e-031.00e+008.729112
GO:0090204protein localization to nuclear pore2.36e-031.00e+008.729112
GO:0009786regulation of asymmetric cell division2.36e-031.00e+008.729112
GO:0070840dynein complex binding2.36e-031.00e+008.729112
GO:0019427acetyl-CoA biosynthetic process from acetate2.36e-031.00e+008.729112
GO:0019413acetate biosynthetic process2.36e-031.00e+008.729112
GO:0060661submandibular salivary gland formation2.36e-031.00e+008.729112
GO:0046832negative regulation of RNA export from nucleus2.36e-031.00e+008.729112
GO:0000189MAPK import into nucleus2.36e-031.00e+008.729112
GO:0019542propionate biosynthetic process2.36e-031.00e+008.729112
GO:0090135actin filament branching2.36e-031.00e+008.729112
GO:0002944cyclin K-CDK12 complex2.36e-031.00e+008.729112
GO:0060070canonical Wnt signaling pathway3.45e-031.00e+004.5002475
GO:0051683establishment of Golgi localization3.53e-031.00e+008.144113
GO:0034191apolipoprotein A-I receptor binding3.53e-031.00e+008.144113
GO:0046914transition metal ion binding3.53e-031.00e+008.144113
GO:0003987acetate-CoA ligase activity3.53e-031.00e+008.144113
GO:0042306regulation of protein import into nucleus3.53e-031.00e+008.144123
GO:0060913cardiac cell fate determination3.53e-031.00e+008.144113
GO:0001650fibrillar center3.53e-031.00e+008.144113
GO:0003161cardiac conduction system development3.53e-031.00e+008.144113
GO:0090245axis elongation involved in somitogenesis3.53e-031.00e+008.144113
GO:0019908nuclear cyclin-dependent protein kinase holoenzyme complex3.53e-031.00e+008.144113
GO:0006405RNA export from nucleus3.53e-031.00e+008.144123
GO:0033688regulation of osteoblast proliferation3.53e-031.00e+008.144113
GO:0003130BMP signaling pathway involved in heart induction3.53e-031.00e+008.144113
GO:0014044Schwann cell development4.71e-031.00e+007.729114
GO:0038027apolipoprotein A-I-mediated signaling pathway4.71e-031.00e+007.729114
GO:0030578PML body organization4.71e-031.00e+007.729114
GO:0048664neuron fate determination4.71e-031.00e+007.729114
GO:0060684epithelial-mesenchymal cell signaling4.71e-031.00e+007.729114
GO:0051835positive regulation of synapse structural plasticity4.71e-031.00e+007.729114
GO:0006999nuclear pore organization4.71e-031.00e+007.729114
GO:0072384organelle transport along microtubule4.71e-031.00e+007.729114
GO:0044615nuclear pore nuclear basket4.71e-031.00e+007.729114
GO:0051726regulation of cell cycle5.70e-031.00e+004.1292597
GO:0001714endodermal cell fate specification5.88e-031.00e+007.407115
GO:0090267positive regulation of mitotic cell cycle spindle assembly checkpoint5.88e-031.00e+007.407115
GO:0070934CRD-mediated mRNA stabilization5.88e-031.00e+007.407125
GO:0036336dendritic cell migration5.88e-031.00e+007.407115
GO:0035088establishment or maintenance of apical/basal cell polarity5.88e-031.00e+007.407115
GO:0031256leading edge membrane5.88e-031.00e+007.407115
GO:0010793regulation of mRNA export from nucleus5.88e-031.00e+007.407115
GO:0043405regulation of MAP kinase activity5.88e-031.00e+007.407115
GO:0070849response to epidermal growth factor5.88e-031.00e+007.407115
GO:0007176regulation of epidermal growth factor-activated receptor activity5.88e-031.00e+007.407115
GO:0010467gene expression6.73e-031.00e+002.343445669
GO:0030496midbody7.02e-031.00e+003.97422108
GO:0007097nuclear migration7.05e-031.00e+007.144116
GO:0003334keratinocyte development7.05e-031.00e+007.144116
GO:0036089cleavage furrow formation7.05e-031.00e+007.144126
GO:0050733RS domain binding7.05e-031.00e+007.144116
GO:0070937CRD-mediated mRNA stability complex7.05e-031.00e+007.144136
GO:0060789hair follicle placode formation7.05e-031.00e+007.144126
GO:0048554positive regulation of metalloenzyme activity7.05e-031.00e+007.144116
GO:0043497regulation of protein heterodimerization activity7.05e-031.00e+007.144116
GO:0051056regulation of small GTPase mediated signal transduction7.93e-031.00e+003.88323115
GO:0046825regulation of protein export from nucleus8.22e-031.00e+006.921127
GO:0051988regulation of attachment of spindle microtubules to kinetochore8.22e-031.00e+006.921127
GO:0043931ossification involved in bone maturation8.22e-031.00e+006.921117
GO:0051489regulation of filopodium assembly8.22e-031.00e+006.921117
GO:0043297apical junction assembly8.22e-031.00e+006.921117
GO:0030036actin cytoskeleton organization9.02e-031.00e+003.78623123
GO:0097202activation of cysteine-type endopeptidase activity9.39e-031.00e+006.729118
GO:0051292nuclear pore complex assembly9.39e-031.00e+006.729148
GO:0007617mating behavior9.39e-031.00e+006.729118
GO:0035457cellular response to interferon-alpha9.39e-031.00e+006.729118
GO:0016020membrane9.85e-031.00e+001.5986461681
GO:0042405nuclear inclusion body1.06e-021.00e+006.559129
GO:0016208AMP binding1.06e-021.00e+006.559119
GO:0090136epithelial cell-cell adhesion1.06e-021.00e+006.559119
GO:0043495protein anchor1.06e-021.00e+006.559119
GO:0043296apical junction complex1.06e-021.00e+006.559119
GO:0031274positive regulation of pseudopodium assembly1.17e-021.00e+006.4071210
GO:0060071Wnt signaling pathway, planar cell polarity pathway1.17e-021.00e+006.4071110
GO:0090307spindle assembly involved in mitosis1.17e-021.00e+006.4071110
GO:0035413positive regulation of catenin import into nucleus1.17e-021.00e+006.4071210
GO:0006069ethanol oxidation1.17e-021.00e+006.4071110
GO:0060047heart contraction1.17e-021.00e+006.4071110
GO:0019789SUMO ligase activity1.29e-021.00e+006.2691111
GO:0060391positive regulation of SMAD protein import into nucleus1.29e-021.00e+006.2691411
GO:0006878cellular copper ion homeostasis1.41e-021.00e+006.1441112
GO:0045947negative regulation of translational initiation1.41e-021.00e+006.1441212
GO:0034399nuclear periphery1.41e-021.00e+006.1441512
GO:0005838proteasome regulatory particle1.41e-021.00e+006.1441112
GO:0035198miRNA binding1.41e-021.00e+006.1441112
GO:0006397mRNA processing1.49e-021.00e+003.407210160
GO:0071480cellular response to gamma radiation1.52e-021.00e+006.0281113
GO:0042789mRNA transcription from RNA polymerase II promoter1.52e-021.00e+006.0281213
GO:0051019mitogen-activated protein kinase binding1.52e-021.00e+006.0281213
GO:0031334positive regulation of protein complex assembly1.52e-021.00e+006.0281213
GO:0032039integrator complex1.52e-021.00e+006.0281113
GO:0005868cytoplasmic dynein complex1.52e-021.00e+006.0281113
GO:0030234enzyme regulator activity1.52e-021.00e+006.0281213
GO:0046827positive regulation of protein export from nucleus1.52e-021.00e+006.0281113
GO:0001967suckling behavior1.64e-021.00e+005.9211114
GO:0030518intracellular steroid hormone receptor signaling pathway1.64e-021.00e+005.9211614
GO:0031333negative regulation of protein complex assembly1.64e-021.00e+005.9211114
GO:0031996thioesterase binding1.64e-021.00e+005.9211114
GO:0031965nuclear membrane1.64e-021.00e+003.336210168
GO:0044212transcription regulatory region DNA binding1.64e-021.00e+003.336217168
GO:0005487nucleocytoplasmic transporter activity1.64e-021.00e+005.9211314
GO:0042809vitamin D receptor binding1.75e-021.00e+005.8221615
GO:0042307positive regulation of protein import into nucleus1.75e-021.00e+005.8221415
GO:0030225macrophage differentiation1.75e-021.00e+005.8221215
GO:0001824blastocyst development1.75e-021.00e+005.8221215
GO:0051233spindle midzone1.75e-021.00e+005.8221215
GO:0031625ubiquitin protein ligase binding1.82e-021.00e+003.25325178
GO:0005634nucleus1.86e-021.00e+000.896101594559
GO:0008353RNA polymerase II carboxy-terminal domain kinase activity1.87e-021.00e+005.7291116
GO:0060334regulation of interferon-gamma-mediated signaling pathway1.87e-021.00e+005.7291116
GO:0001190RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription1.87e-021.00e+005.7291216
GO:0006367transcription initiation from RNA polymerase II promoter1.94e-021.00e+003.205222184
GO:0050919negative chemotaxis1.99e-021.00e+005.6411117
GO:0017022myosin binding1.99e-021.00e+005.6411217
GO:0030742GTP-dependent protein binding1.99e-021.00e+005.6411117
GO:0022624proteasome accessory complex1.99e-021.00e+005.6411117
GO:0030332cyclin binding2.10e-021.00e+005.5591118
GO:0050772positive regulation of axonogenesis2.10e-021.00e+005.5591118
GO:0007088regulation of mitosis2.10e-021.00e+005.5591118
GO:0042346positive regulation of NF-kappaB import into nucleus2.10e-021.00e+005.5591118
GO:0003924GTPase activity2.21e-021.00e+003.10727197
GO:0046847filopodium assembly2.22e-021.00e+005.4811119
GO:0050771negative regulation of axonogenesis2.33e-021.00e+005.4071120
GO:0016032viral process2.33e-021.00e+002.253326534
GO:0014003oligodendrocyte development2.33e-021.00e+005.4071520
GO:0043393regulation of protein binding2.33e-021.00e+005.4071120
GO:0031435mitogen-activated protein kinase kinase kinase binding2.45e-021.00e+005.3361121
GO:0045862positive regulation of proteolysis2.45e-021.00e+005.3361221
GO:0031424keratinization2.56e-021.00e+005.2691122
GO:0043484regulation of RNA splicing2.56e-021.00e+005.2691122
GO:0006184GTP catabolic process2.57e-021.00e+002.98727214
GO:1900026positive regulation of substrate adhesion-dependent cell spreading2.68e-021.00e+005.2051323
GO:0002040sprouting angiogenesis2.68e-021.00e+005.2051223
GO:0051017actin filament bundle assembly2.68e-021.00e+005.2051123
GO:0019221cytokine-mediated signaling pathway2.73e-021.00e+002.94128221
GO:0007163establishment or maintenance of cell polarity2.79e-021.00e+005.1441224
GO:1902017regulation of cilium assembly2.79e-021.00e+005.1441224
GO:0006611protein export from nucleus2.91e-021.00e+005.0851325
GO:0016925protein sumoylation2.91e-021.00e+005.0851225
GO:0035329hippo signaling3.02e-021.00e+005.0281526
GO:0043392negative regulation of DNA binding3.02e-021.00e+005.0281426
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity3.02e-021.00e+005.0281326
GO:0050770regulation of axonogenesis3.02e-021.00e+005.0281226
GO:0046966thyroid hormone receptor binding3.02e-021.00e+005.0281626
GO:0045859regulation of protein kinase activity3.02e-021.00e+005.0281126
GO:0003713transcription coactivator activity3.11e-021.00e+002.840224237
GO:0015631tubulin binding3.14e-021.00e+004.9741227
GO:0051149positive regulation of muscle cell differentiation3.14e-021.00e+004.9741427
GO:0031069hair follicle morphogenesis3.14e-021.00e+004.9741127
GO:0008134transcription factor binding3.23e-021.00e+002.810218242
GO:0034605cellular response to heat3.25e-021.00e+004.9211128
GO:0019894kinesin binding3.25e-021.00e+004.9211128
GO:0030901midbrain development3.37e-021.00e+004.8711129
GO:0006606protein import into nucleus3.48e-021.00e+004.8221230
GO:0010827regulation of glucose transport3.48e-021.00e+004.8221430
GO:0004693cyclin-dependent protein serine/threonine kinase activity3.59e-021.00e+004.7741131
GO:0007094mitotic spindle assembly checkpoint3.59e-021.00e+004.7741331
GO:1903507negative regulation of nucleic acid-templated transcription3.71e-021.00e+004.7291232
GO:0031072heat shock protein binding3.82e-021.00e+004.6841233
GO:0001104RNA polymerase II transcription cofactor activity3.82e-021.00e+004.6841833
GO:0005097Rab GTPase activator activity3.93e-021.00e+004.6411134
GO:0042692muscle cell differentiation3.93e-021.00e+004.6411434
GO:0016592mediator complex4.05e-021.00e+004.59911035
GO:0030178negative regulation of Wnt signaling pathway4.05e-021.00e+004.5991435
GO:0034332adherens junction organization4.16e-021.00e+004.5591236
GO:0007077mitotic nuclear envelope disassembly4.16e-021.00e+004.5591436
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway4.16e-021.00e+004.5591236
GO:0045740positive regulation of DNA replication4.16e-021.00e+004.5591136
GO:0007264small GTPase mediated signal transduction4.19e-021.00e+002.60423279
GO:0032880regulation of protein localization4.28e-021.00e+004.5191237
GO:0005902microvillus4.39e-021.00e+004.4811338
GO:0051496positive regulation of stress fiber assembly4.39e-021.00e+004.4811438
GO:0032154cleavage furrow4.39e-021.00e+004.4811138
GO:0008645hexose transport4.50e-021.00e+004.4431439
GO:0035019somatic stem cell maintenance4.61e-021.00e+004.4071640
GO:0050885neuromuscular process controlling balance4.61e-021.00e+004.4071240
GO:0042147retrograde transport, endosome to Golgi4.73e-021.00e+004.3711141
GO:0030521androgen receptor signaling pathway4.73e-021.00e+004.3711541
GO:0019898extrinsic component of membrane4.84e-021.00e+004.3361242
GO:0003677DNA binding4.95e-021.00e+001.4784491218
GO:0030374ligand-dependent nuclear receptor transcription coactivator activity4.95e-021.00e+004.3021743
GO:0032436positive regulation of proteasomal ubiquitin-dependent protein catabolic process5.06e-021.00e+004.2691344
GO:0034613cellular protein localization5.06e-021.00e+004.2691244
GO:0003712transcription cofactor activity5.06e-021.00e+004.2691844
GO:0005525GTP binding5.06e-021.00e+002.452212310
GO:0043525positive regulation of neuron apoptotic process5.29e-021.00e+004.2051446
GO:0007411axon guidance5.33e-021.00e+002.41125319
GO:0007266Rho protein signal transduction5.40e-021.00e+004.1741147
GO:0019827stem cell maintenance5.40e-021.00e+004.1741747
GO:0003682chromatin binding5.57e-021.00e+002.375219327
GO:0007030Golgi organization5.62e-021.00e+004.1141349
GO:0030900forebrain development5.62e-021.00e+004.1141149
GO:0006521regulation of cellular amino acid metabolic process5.74e-021.00e+004.0851150
GO:0030175filopodium5.74e-021.00e+004.0851150
GO:0030334regulation of cell migration5.74e-021.00e+004.0851550
GO:0000910cytokinesis5.85e-021.00e+004.0561251
GO:0000226microtubule cytoskeleton organization5.96e-021.00e+004.0281252
GO:0009611response to wounding5.96e-021.00e+004.0281552
GO:0003723RNA binding6.03e-021.00e+002.311218342
GO:0032851positive regulation of Rab GTPase activity6.07e-021.00e+004.0011253
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding6.07e-021.00e+004.0011553
GO:0015758glucose transport6.29e-021.00e+003.9471455
GO:0046330positive regulation of JNK cascade6.29e-021.00e+003.9471255
GO:0000724double-strand break repair via homologous recombination6.29e-021.00e+003.9471255
GO:0007018microtubule-based movement6.51e-021.00e+003.8961157
GO:0008203cholesterol metabolic process6.51e-021.00e+003.8961257
GO:0033138positive regulation of peptidyl-serine phosphorylation6.73e-021.00e+003.8461259
GO:0006396RNA processing6.73e-021.00e+003.8461559
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity6.73e-021.00e+003.8461659
GO:0005925focal adhesion6.80e-021.00e+002.21329366
GO:0008013beta-catenin binding6.85e-021.00e+003.8221960
GO:0060333interferon-gamma-mediated signaling pathway7.07e-021.00e+003.7741362
GO:0030141secretory granule7.07e-021.00e+003.7741462
GO:0004867serine-type endopeptidase inhibitor activity7.18e-021.00e+003.7511363
GO:0000776kinetochore7.18e-021.00e+003.7511563
GO:0045666positive regulation of neuron differentiation7.18e-021.00e+003.7511363
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest7.29e-021.00e+003.7291164
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle7.40e-021.00e+003.7061265
GO:0031295T cell costimulation7.40e-021.00e+003.7061165
GO:0035264multicellular organism growth7.61e-021.00e+003.6631267
GO:0000278mitotic cell cycle7.63e-021.00e+002.118215391
GO:0010468regulation of gene expression7.72e-021.00e+003.6411268
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle7.94e-021.00e+003.5991270
GO:0005085guanyl-nucleotide exchange factor activity8.05e-021.00e+003.5791571
GO:0007626locomotory behavior8.05e-021.00e+003.5791271
GO:0060021palate development8.16e-021.00e+003.5591172
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent8.16e-021.00e+003.5591172
GO:0003729mRNA binding8.16e-021.00e+003.5591472
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis8.38e-021.00e+003.5191274
GO:0001843neural tube closure8.38e-021.00e+003.5191274
GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity8.38e-021.00e+003.5191474
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.38e-021.00e+003.5191274
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I8.49e-021.00e+003.5001175
GO:0010629negative regulation of gene expression8.70e-021.00e+003.4621477
GO:0043066negative regulation of apoptotic process8.77e-021.00e+002.001216424
GO:0071013catalytic step 2 spliceosome8.81e-021.00e+003.4431778
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process8.92e-021.00e+003.4251279
GO:0045177apical part of cell9.13e-021.00e+003.3891381
GO:0009653anatomical structure morphogenesis9.35e-021.00e+003.3541283
GO:0007596blood coagulation9.89e-021.00e+001.899211455
GO:0016605PML body9.89e-021.00e+003.2691388
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.03e-011.00e+003.2051192
GO:0001649osteoblast differentiation1.03e-011.00e+003.2051592
GO:0030165PDZ domain binding1.05e-011.00e+003.1741194
GO:0042802identical protein binding1.10e-011.00e+001.810219484
GO:0006805xenobiotic metabolic process1.15e-011.00e+003.04212103
GO:0010951negative regulation of endopeptidase activity1.16e-011.00e+003.02816104
GO:0005938cell cortex1.16e-011.00e+003.02815104
GO:0005730nucleolus1.19e-011.00e+001.0484661641
GO:0003676nucleic acid binding1.19e-011.00e+002.98712107
GO:0005815microtubule organizing center1.21e-011.00e+002.96013109
GO:0030529ribonucleoprotein complex1.24e-011.00e+002.92115112
GO:0005635nuclear envelope1.25e-011.00e+002.90815113
GO:0048015phosphatidylinositol-mediated signaling1.26e-011.00e+002.89612114
GO:0000209protein polyubiquitination1.28e-011.00e+002.87113116
GO:0008201heparin binding1.35e-011.00e+002.79811122
GO:0030027lamellipodium1.38e-011.00e+002.76317125
GO:0070062extracellular vesicular exosome1.39e-011.00e+000.8225572400
GO:0007179transforming growth factor beta receptor signaling pathway1.41e-011.00e+002.729111128
GO:0005215transporter activity1.43e-011.00e+002.70613130
GO:0005911cell-cell junction1.49e-011.00e+002.64112136
GO:0045202synapse1.49e-011.00e+002.64115136
GO:0007507heart development1.52e-011.00e+002.61017139
GO:0005829cytosol1.57e-011.00e+000.7655862496
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling1.58e-011.00e+002.54914145
GO:0010628positive regulation of gene expression1.59e-011.00e+002.53917146
GO:0000082G1/S transition of mitotic cell cycle1.62e-011.00e+002.50913149
GO:0042981regulation of apoptotic process1.63e-011.00e+002.50014150
GO:0006974cellular response to DNA damage stimulus1.64e-011.00e+002.49017151
GO:0044281small molecule metabolic process1.67e-011.00e+001.0723201211
GO:0043005neuron projection1.70e-011.00e+002.43413157
GO:0046777protein autophosphorylation1.71e-011.00e+002.42514158
GO:0008022protein C-terminus binding1.74e-011.00e+002.39818161
GO:0043687post-translational protein modification1.75e-011.00e+002.38915162
GO:0000398mRNA splicing, via spliceosome1.77e-011.00e+002.371115164
GO:0034641cellular nitrogen compound metabolic process1.84e-011.00e+002.31112171
GO:0005667transcription factor complex1.88e-011.00e+002.277117175
GO:0004672protein kinase activity1.89e-011.00e+002.26113177
GO:0003714transcription corepressor activity1.90e-011.00e+002.253111178
GO:0019904protein domain specific binding1.91e-011.00e+002.24518179
GO:0005524ATP binding1.93e-011.00e+000.9723311298
GO:0004872receptor activity2.01e-011.00e+002.16618189
GO:0007173epidermal growth factor receptor signaling pathway2.01e-011.00e+002.16615189
GO:0030168platelet activation2.16e-011.00e+002.04916205
GO:0016071mRNA metabolic process2.33e-011.00e+001.92818223
GO:0007067mitotic nuclear division2.36e-011.00e+001.90216227
GO:0005759mitochondrial matrix2.37e-011.00e+001.89614228
GO:0045944positive regulation of transcription from RNA polymerase II promoter2.38e-011.00e+001.105241789
GO:0030425dendrite2.39e-011.00e+001.88316230
GO:0043025neuronal cell body2.53e-011.00e+001.79219245
GO:0016070RNA metabolic process2.55e-011.00e+001.78018247
GO:0005975carbohydrate metabolic process2.60e-011.00e+001.74618253
GO:0006281DNA repair2.67e-011.00e+001.701114261
GO:0048011neurotrophin TRK receptor signaling pathway2.74e-011.00e+001.65717269
GO:0030198extracellular matrix organization2.86e-011.00e+001.58416283
GO:0007186G-protein coupled receptor signaling pathway2.91e-011.00e+001.55411289
GO:0005856cytoskeleton2.93e-011.00e+001.54419291
GO:0019901protein kinase binding3.15e-011.00e+001.420118317
GO:0008283cell proliferation3.24e-011.00e+001.371114328
GO:0030054cell junction3.30e-011.00e+001.33615336
GO:0006355regulation of transcription, DNA-templated3.31e-011.00e+000.767243997
GO:0043565sequence-specific DNA binding3.38e-011.00e+001.294111346
GO:0000139Golgi membrane3.50e-011.00e+001.23317361
GO:0005886plasma membrane3.63e-011.00e+000.3944492582
GO:0009986cell surface3.82e-011.00e+001.07819402
GO:0045892negative regulation of transcription, DNA-templated3.90e-011.00e+001.039124413
GO:0006366transcription from RNA polymerase II promoter3.94e-011.00e+001.018130419
GO:0055085transmembrane transport4.06e-011.00e+000.96418435
GO:0044267cellular protein metabolic process4.34e-011.00e+000.840120474
GO:0045893positive regulation of transcription, DNA-templated4.36e-011.00e+000.828124478
GO:0005737cytoplasm4.69e-011.00e+000.17151243767
GO:0006915apoptotic process4.87e-011.00e+000.612112555
GO:0005783endoplasmic reticulum4.88e-011.00e+000.610113556
GO:0005789endoplasmic reticulum membrane4.96e-011.00e+000.57419570
GO:0000122negative regulation of transcription from RNA polymerase II promoter4.96e-011.00e+000.574137570
GO:0042803protein homodimerization activity5.12e-011.00e+000.512119595
GO:0045087innate immune response5.12e-011.00e+000.509115596
GO:0003700sequence-specific DNA binding transcription factor activity5.70e-011.00e+000.279139699
GO:0005887integral component of plasma membrane6.61e-011.00e+00-0.066110888
GO:0016021integral component of membrane7.00e-011.00e+00-0.2242171982
GO:0046872metal ion binding8.01e-011.00e+00-0.6231291307