int-snw-3516

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.829	1.92e-15	5.19e-04	3.56e-03

chia-screen-data-Fav-int-snw-3516 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
NFRKB	4798	48	-3.129	3.108	23	Yes	Yes
TAF12	6883	1	-2.134	2.829	35	Yes	-
[ RBPJ ]	3516	1	-1.698	2.829	48	-	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
CDX2	1045	3	-2.037	2.955	33	Yes	Yes

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDX2	1045	RBPJ	3516	pp	--	int.I2D: I2D-c_Mouse
RBPJ	3516	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse
RBPJ	3516	TAF12	6883	pp	--	int.I2D: MINT_Fly, BioGrid_Fly, FlyLow, IntAct_Fly
NFRKB	4798	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse

Related GO terms (120)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0035019	somatic stem cell maintenance	1.97e-07	2.84e-03	7.757	3	6	40
GO:0006366	transcription from RNA polymerase II promoter	3.43e-06	4.95e-02	4.783	4	30	419
GO:0003700	sequence-specific DNA binding transcription factor activity	2.63e-05	3.79e-01	4.045	4	39	699
GO:0006310	DNA recombination	1.98e-04	1.00e+00	6.472	2	7	65
GO:0003677	DNA binding	2.36e-04	1.00e+00	3.244	4	49	1218
GO:0060844	arterial endothelial cell fate commitment	3.47e-04	1.00e+00	11.494	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	3.47e-04	1.00e+00	11.494	1	1	1
GO:1901297	positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	3.47e-04	1.00e+00	11.494	1	1	1
GO:0097101	blood vessel endothelial cell fate specification	3.47e-04	1.00e+00	11.494	1	1	1
GO:0009957	epidermal cell fate specification	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	3.47e-04	1.00e+00	11.494	1	1	1
GO:1901186	positive regulation of ERBB signaling pathway	3.47e-04	1.00e+00	11.494	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	3.47e-04	1.00e+00	11.494	1	1	1
GO:1901189	positive regulation of ephrin receptor signaling pathway	3.47e-04	1.00e+00	11.494	1	1	1
GO:0000150	recombinase activity	3.47e-04	1.00e+00	11.494	1	1	1
GO:0072554	blood vessel lumenization	6.93e-04	1.00e+00	10.494	1	1	2
GO:0003160	endocardium morphogenesis	6.93e-04	1.00e+00	10.494	1	1	2
GO:0009786	regulation of asymmetric cell division	6.93e-04	1.00e+00	10.494	1	1	2
GO:0048820	hair follicle maturation	6.93e-04	1.00e+00	10.494	1	1	2
GO:0002193	MAML1-RBP-Jkappa- ICN1 complex	1.04e-03	1.00e+00	9.909	1	1	3
GO:0060913	cardiac cell fate determination	1.04e-03	1.00e+00	9.909	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.04e-03	1.00e+00	9.909	1	1	3
GO:0003256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	1.04e-03	1.00e+00	9.909	1	1	3
GO:0009912	auditory receptor cell fate commitment	1.04e-03	1.00e+00	9.909	1	1	3
GO:0007221	positive regulation of transcription of Notch receptor target	1.39e-03	1.00e+00	9.494	1	1	4
GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis	1.39e-03	1.00e+00	9.494	1	1	4
GO:0060486	Clara cell differentiation	1.39e-03	1.00e+00	9.494	1	1	4
GO:0005667	transcription factor complex	1.43e-03	1.00e+00	5.043	2	17	175
GO:0006367	transcription initiation from RNA polymerase II promoter	1.58e-03	1.00e+00	4.971	2	22	184
GO:0001714	endodermal cell fate specification	1.73e-03	1.00e+00	9.172	1	1	5
GO:0048505	regulation of timing of cell differentiation	1.73e-03	1.00e+00	9.172	1	1	5
GO:0048733	sebaceous gland development	1.73e-03	1.00e+00	9.172	1	1	5
GO:0072602	interleukin-4 secretion	1.73e-03	1.00e+00	9.172	1	1	5
GO:0035912	dorsal aorta morphogenesis	1.73e-03	1.00e+00	9.172	1	1	5
GO:0036302	atrioventricular canal development	1.73e-03	1.00e+00	9.172	1	1	5
GO:0000125	PCAF complex	2.08e-03	1.00e+00	8.909	1	1	6
GO:0003139	secondary heart field specification	2.42e-03	1.00e+00	8.687	1	1	7
GO:0008134	transcription factor binding	2.71e-03	1.00e+00	4.575	2	18	242
GO:0060711	labyrinthine layer development	3.12e-03	1.00e+00	8.324	1	3	9
GO:0003222	ventricular trabecula myocardium morphogenesis	3.12e-03	1.00e+00	8.324	1	1	9
GO:0003198	epithelial to mesenchymal transition involved in endocardial cushion formation	3.12e-03	1.00e+00	8.324	1	1	9
GO:0061314	Notch signaling involved in heart development	3.12e-03	1.00e+00	8.324	1	1	9
GO:0003214	cardiac left ventricle morphogenesis	3.12e-03	1.00e+00	8.324	1	1	9
GO:0035413	positive regulation of catenin import into nucleus	3.46e-03	1.00e+00	8.172	1	2	10
GO:0045197	establishment or maintenance of epithelial cell apical/basal polarity	3.46e-03	1.00e+00	8.172	1	1	10
GO:0005654	nucleoplasm	3.75e-03	1.00e+00	3.000	3	64	1082
GO:0060391	positive regulation of SMAD protein import into nucleus	3.81e-03	1.00e+00	8.035	1	4	11
GO:0035198	miRNA binding	4.15e-03	1.00e+00	7.909	1	1	12
GO:0042789	mRNA transcription from RNA polymerase II promoter	4.50e-03	1.00e+00	7.794	1	2	13
GO:0030914	STAGA complex	4.50e-03	1.00e+00	7.794	1	3	13
GO:0002437	inflammatory response to antigenic stimulus	4.84e-03	1.00e+00	7.687	1	1	14
GO:0031011	Ino80 complex	4.84e-03	1.00e+00	7.687	1	6	14
GO:0033276	transcription factor TFTC complex	4.84e-03	1.00e+00	7.687	1	4	14
GO:0030279	negative regulation of ossification	4.84e-03	1.00e+00	7.687	1	2	14
GO:0001824	blastocyst development	5.19e-03	1.00e+00	7.587	1	2	15
GO:0043565	sequence-specific DNA binding	5.47e-03	1.00e+00	4.060	2	11	346
GO:0001829	trophectodermal cell differentiation	5.88e-03	1.00e+00	7.407	1	2	17
GO:1903506	regulation of nucleic acid-templated transcription	6.23e-03	1.00e+00	7.324	1	1	18
GO:0060716	labyrinthine layer blood vessel development	6.23e-03	1.00e+00	7.324	1	1	18
GO:0060045	positive regulation of cardiac muscle cell proliferation	6.57e-03	1.00e+00	7.246	1	1	19
GO:0006352	DNA-templated transcription, initiation	6.92e-03	1.00e+00	7.172	1	2	20
GO:0005669	transcription factor TFIID complex	7.60e-03	1.00e+00	7.035	1	4	22
GO:0000794	condensed nuclear chromosome	8.29e-03	1.00e+00	6.909	1	1	24
GO:0030513	positive regulation of BMP signaling pathway	8.98e-03	1.00e+00	6.794	1	1	26
GO:0001103	RNA polymerase II repressing transcription factor binding	9.33e-03	1.00e+00	6.739	1	2	27
GO:0021983	pituitary gland development	9.33e-03	1.00e+00	6.739	1	2	27
GO:0045597	positive regulation of cell differentiation	9.33e-03	1.00e+00	6.739	1	1	27
GO:0008333	endosome to lysosome transport	1.00e-02	1.00e+00	6.636	1	2	29
GO:0001974	blood vessel remodeling	1.10e-02	1.00e+00	6.494	1	1	32
GO:0001837	epithelial to mesenchymal transition	1.14e-02	1.00e+00	6.450	1	2	33
GO:0001568	blood vessel development	1.21e-02	1.00e+00	6.365	1	2	35
GO:0005730	nucleolus	1.23e-02	1.00e+00	2.399	3	66	1641
GO:0003151	outflow tract morphogenesis	1.31e-02	1.00e+00	6.246	1	1	38
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.44e-02	1.00e+00	3.339	2	37	570
GO:0004402	histone acetyltransferase activity	1.48e-02	1.00e+00	6.068	1	6	43
GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	1.52e-02	1.00e+00	6.035	1	4	44
GO:0043966	histone H3 acetylation	1.55e-02	1.00e+00	6.002	1	5	45
GO:0030216	keratinocyte differentiation	1.62e-02	1.00e+00	5.940	1	2	47
GO:0006959	humoral immune response	1.62e-02	1.00e+00	5.940	1	3	47
GO:0017053	transcriptional repressor complex	1.76e-02	1.00e+00	5.822	1	2	51
GO:0009611	response to wounding	1.79e-02	1.00e+00	5.794	1	5	52
GO:0030183	B cell differentiation	1.86e-02	1.00e+00	5.739	1	1	54
GO:0010467	gene expression	1.96e-02	1.00e+00	3.108	2	45	669
GO:0042742	defense response to bacterium	2.06e-02	1.00e+00	5.587	1	5	60
GO:0006368	transcription elongation from RNA polymerase II promoter	2.30e-02	1.00e+00	5.428	1	6	67
GO:0010468	regulation of gene expression	2.34e-02	1.00e+00	5.407	1	2	68
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	2.54e-02	1.00e+00	5.285	1	4	74
GO:0002020	protease binding	2.54e-02	1.00e+00	5.285	1	6	74
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.68e-02	1.00e+00	2.870	2	41	789
GO:0009653	anatomical structure morphogenesis	2.84e-02	1.00e+00	5.119	1	2	83
GO:0009952	anterior/posterior pattern specification	2.84e-02	1.00e+00	5.119	1	4	83
GO:0009887	organ morphogenesis	2.95e-02	1.00e+00	5.068	1	5	86
GO:0047485	protein N-terminus binding	2.95e-02	1.00e+00	5.068	1	3	86
GO:0003690	double-stranded DNA binding	2.95e-02	1.00e+00	5.068	1	3	86
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	3.15e-02	1.00e+00	4.971	1	7	92
GO:0005634	nucleus	3.73e-02	1.00e+00	1.340	4	159	4559
GO:0006325	chromatin organization	4.02e-02	1.00e+00	4.612	1	12	118
GO:0007219	Notch signaling pathway	4.09e-02	1.00e+00	4.587	1	5	120
GO:0006355	regulation of transcription, DNA-templated	4.15e-02	1.00e+00	2.533	2	43	997
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	4.99e-02	1.00e+00	4.294	1	6	147
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	5.59e-02	1.00e+00	4.128	1	12	165
GO:0044212	transcription regulatory region DNA binding	5.69e-02	1.00e+00	4.102	1	17	168
GO:0031625	ubiquitin protein ligase binding	6.02e-02	1.00e+00	4.018	1	5	178
GO:0003714	transcription corepressor activity	6.02e-02	1.00e+00	4.018	1	11	178
GO:0001525	angiogenesis	6.45e-02	1.00e+00	3.917	1	7	191
GO:0003713	transcription coactivator activity	7.95e-02	1.00e+00	3.605	1	24	237
GO:0006281	DNA repair	8.73e-02	1.00e+00	3.466	1	14	261
GO:0006954	inflammatory response	9.24e-02	1.00e+00	3.380	1	6	277
GO:0005515	protein binding	1.01e-01	1.00e+00	0.938	4	198	6024
GO:0003682	chromatin binding	1.08e-01	1.00e+00	3.141	1	19	327
GO:0008285	negative regulation of cell proliferation	1.17e-01	1.00e+00	3.031	1	10	353
GO:0046982	protein heterodimerization activity	1.25e-01	1.00e+00	2.924	1	8	380
GO:0008284	positive regulation of cell proliferation	1.26e-01	1.00e+00	2.917	1	10	382
GO:0045892	negative regulation of transcription, DNA-templated	1.35e-01	1.00e+00	2.804	1	24	413
GO:0045893	positive regulation of transcription, DNA-templated	1.55e-01	1.00e+00	2.593	1	24	478
GO:0016032	viral process	1.72e-01	1.00e+00	2.433	1	26	534
GO:0044822	poly(A) RNA binding	3.16e-01	1.00e+00	1.450	1	50	1056
GO:0005737	cytoplasm	3.91e-01	1.00e+00	0.615	2	124	3767
GO:0005829	cytosol	6.13e-01	1.00e+00	0.209	1	86	2496

chia-Fav

int-snw-3516

Statistics

Genes (5)

Interactions (4)

Related GO terms (120)