int-snw-219541

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.449	6.47e-23	4.30e-08	4.24e-06

chia-screen-data-Fav-int-snw-219541 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
HCFC1	3054	40	-2.925	3.449	71	Yes	Yes
[ MED19 ]	219541	30	-2.657	3.449	115	Yes	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
LUC7L3	51747	33	-3.523	3.449	18	Yes	-

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
SRSF3	6428	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
LUC7L3	51747	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct
HCFC1	3054	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HCFC1	3054	MED19	219541	pp	--	int.Intact: MI:0914(association); int.I2D: IntAct

Related GO terms (80)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006366	transcription from RNA polymerase II promoter	3.43e-06	4.95e-02	4.783	4	30	419
GO:0060795	cell fate commitment involved in formation of primary germ layer	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	3.47e-04	1.00e+00	11.494	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	3.47e-04	1.00e+00	11.494	1	1	1
GO:0019046	release from viral latency	6.93e-04	1.00e+00	10.494	1	2	2
GO:0009786	regulation of asymmetric cell division	6.93e-04	1.00e+00	10.494	1	1	2
GO:0060913	cardiac cell fate determination	1.04e-03	1.00e+00	9.909	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.04e-03	1.00e+00	9.909	1	1	3
GO:0016607	nuclear speck	1.38e-03	1.00e+00	5.068	2	12	172
GO:0001714	endodermal cell fate specification	1.73e-03	1.00e+00	9.172	1	1	5
GO:0070461	SAGA-type complex	1.73e-03	1.00e+00	9.172	1	2	5
GO:0008380	RNA splicing	2.41e-03	1.00e+00	4.661	2	22	228
GO:0070688	MLL5-L complex	2.77e-03	1.00e+00	8.494	1	1	8
GO:0043254	regulation of protein complex assembly	2.77e-03	1.00e+00	8.494	1	1	8
GO:0043995	histone acetyltransferase activity (H4-K5 specific)	3.12e-03	1.00e+00	8.324	1	5	9
GO:0046972	histone acetyltransferase activity (H4-K16 specific)	3.12e-03	1.00e+00	8.324	1	5	9
GO:0043996	histone acetyltransferase activity (H4-K8 specific)	3.12e-03	1.00e+00	8.324	1	5	9
GO:0048188	Set1C/COMPASS complex	3.12e-03	1.00e+00	8.324	1	4	9
GO:0035413	positive regulation of catenin import into nucleus	3.46e-03	1.00e+00	8.172	1	2	10
GO:0044822	poly(A) RNA binding	3.50e-03	1.00e+00	3.035	3	50	1056
GO:0005654	nucleoplasm	3.75e-03	1.00e+00	3.000	3	64	1082
GO:0060391	positive regulation of SMAD protein import into nucleus	3.81e-03	1.00e+00	8.035	1	4	11
GO:0035198	miRNA binding	4.15e-03	1.00e+00	7.909	1	1	12
GO:0042789	mRNA transcription from RNA polymerase II promoter	4.50e-03	1.00e+00	7.794	1	2	13
GO:0005685	U1 snRNP	4.84e-03	1.00e+00	7.687	1	1	14
GO:0043981	histone H4-K5 acetylation	5.19e-03	1.00e+00	7.587	1	5	15
GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex	5.19e-03	1.00e+00	7.587	1	3	15
GO:0006376	mRNA splice site selection	5.19e-03	1.00e+00	7.587	1	1	15
GO:0001824	blastocyst development	5.19e-03	1.00e+00	7.587	1	2	15
GO:0043982	histone H4-K8 acetylation	5.19e-03	1.00e+00	7.587	1	5	15
GO:0043274	phospholipase binding	5.54e-03	1.00e+00	7.494	1	1	16
GO:0043984	histone H4-K16 acetylation	6.57e-03	1.00e+00	7.246	1	5	19
GO:0000123	histone acetyltransferase complex	7.26e-03	1.00e+00	7.102	1	6	21
GO:0045787	positive regulation of cell cycle	7.60e-03	1.00e+00	7.035	1	2	22
GO:0001205	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	7.60e-03	1.00e+00	7.035	1	4	22
GO:0071339	MLL1 complex	9.33e-03	1.00e+00	6.739	1	6	27
GO:0001104	RNA polymerase II transcription cofactor activity	1.14e-02	1.00e+00	6.450	1	8	33
GO:0016592	mediator complex	1.21e-02	1.00e+00	6.365	1	10	35
GO:0035019	somatic stem cell maintenance	1.38e-02	1.00e+00	6.172	1	6	40
GO:0031124	mRNA 3'-end processing	1.45e-02	1.00e+00	6.102	1	2	42
GO:0006369	termination of RNA polymerase II transcription	1.55e-02	1.00e+00	6.002	1	2	45
GO:0009611	response to wounding	1.79e-02	1.00e+00	5.794	1	5	52
GO:0006406	mRNA export from nucleus	2.10e-02	1.00e+00	5.563	1	4	61
GO:0003700	sequence-specific DNA binding transcription factor activity	2.13e-02	1.00e+00	3.045	2	39	699
GO:0010468	regulation of gene expression	2.34e-02	1.00e+00	5.407	1	2	68
GO:0003729	mRNA binding	2.47e-02	1.00e+00	5.324	1	4	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	2.54e-02	1.00e+00	5.285	1	4	74
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.68e-02	1.00e+00	2.870	2	41	789
GO:0009653	anatomical structure morphogenesis	2.84e-02	1.00e+00	5.119	1	2	83
GO:0050821	protein stabilization	3.01e-02	1.00e+00	5.035	1	3	88
GO:0005634	nucleus	3.73e-02	1.00e+00	1.340	4	159	4559
GO:0006325	chromatin organization	4.02e-02	1.00e+00	4.612	1	12	118
GO:0006355	regulation of transcription, DNA-templated	4.15e-02	1.00e+00	2.533	2	43	997
GO:0010628	positive regulation of gene expression	4.96e-02	1.00e+00	4.304	1	7	146
GO:0000398	mRNA splicing, via spliceosome	5.56e-02	1.00e+00	4.137	1	15	164
GO:0044212	transcription regulatory region DNA binding	5.69e-02	1.00e+00	4.102	1	17	168
GO:0007049	cell cycle	5.89e-02	1.00e+00	4.051	1	6	174
GO:0005667	transcription factor complex	5.92e-02	1.00e+00	4.043	1	17	175
GO:0003677	DNA binding	6.00e-02	1.00e+00	2.244	2	49	1218
GO:0031625	ubiquitin protein ligase binding	6.02e-02	1.00e+00	4.018	1	5	178
GO:0003713	transcription coactivator activity	7.95e-02	1.00e+00	3.605	1	24	237
GO:0008134	transcription factor binding	8.11e-02	1.00e+00	3.575	1	18	242
GO:0043025	neuronal cell body	8.21e-02	1.00e+00	3.558	1	9	245
GO:0000166	nucleotide binding	8.66e-02	1.00e+00	3.477	1	13	259
GO:0006357	regulation of transcription from RNA polymerase II promoter	8.82e-02	1.00e+00	3.450	1	23	264
GO:0005515	protein binding	1.01e-01	1.00e+00	0.938	4	198	6024
GO:0005730	nucleolus	1.02e-01	1.00e+00	1.814	2	66	1641
GO:0003682	chromatin binding	1.08e-01	1.00e+00	3.141	1	19	327
GO:0003723	RNA binding	1.13e-01	1.00e+00	3.076	1	18	342
GO:0043565	sequence-specific DNA binding	1.14e-01	1.00e+00	3.060	1	11	346
GO:0005737	cytoplasm	1.16e-01	1.00e+00	1.200	3	124	3767
GO:0005925	focal adhesion	1.21e-01	1.00e+00	2.978	1	9	366
GO:0042802	identical protein binding	1.57e-01	1.00e+00	2.575	1	19	484
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	1.83e-01	1.00e+00	2.339	1	37	570
GO:0010467	gene expression	2.11e-01	1.00e+00	2.108	1	45	669
GO:0005739	mitochondrion	3.01e-01	1.00e+00	1.531	1	23	998
GO:0016020	membrane	4.62e-01	1.00e+00	0.779	1	46	1681
GO:0005829	cytosol	6.13e-01	1.00e+00	0.209	1	86	2496
GO:0005886	plasma membrane	6.27e-01	1.00e+00	0.160	1	49	2582

chia-Fav

int-snw-219541

Statistics

Genes (5)

Interactions (5)

Related GO terms (80)