Subnetwork | Dataset | Score | p-value 1 | p-value 2 | p-value 3 | Size | Highlighted genes |
---|---|---|---|---|---|---|---|
reg-snw-11277 | wolf-screen-ratio-mammosphere-adherent | 0.882 | 1.09e-07 | 9.11e-04 | 1.96e-03 | 10 | 9 |
int-snw-5690 | wolf-screen-ratio-mammosphere-adherent | 1.026 | 3.11e-19 | 2.88e-04 | 7.94e-03 | 7 | 7 |
reg-snw-4522 | wolf-screen-ratio-mammosphere-adherent | 0.815 | 1.50e-06 | 3.75e-03 | 6.95e-03 | 14 | 12 |
reg-snw-56655 | wolf-screen-ratio-mammosphere-adherent | 0.828 | 9.29e-07 | 2.91e-03 | 5.53e-03 | 8 | 7 |
reg-snw-317781 | wolf-screen-ratio-mammosphere-adherent | 0.823 | 1.13e-06 | 3.23e-03 | 6.07e-03 | 9 | 9 |
reg-snw-10213 | wolf-screen-ratio-mammosphere-adherent | 0.815 | 1.49e-06 | 3.74e-03 | 6.93e-03 | 7 | 6 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
PSMB1 | 5689 | 61 | 0.688 | 0.901 | 113 | Yes | - |
PSMA3 | 5684 | 90 | 0.533 | 0.815 | 238 | Yes | - |
PSMA2 | 5683 | 112 | 1.093 | 1.106 | 108 | Yes | - |
RBX1 | 9978 | 115 | 1.185 | 0.934 | 148 | Yes | - |
POLR2F | 5435 | 62 | 0.891 | 0.956 | 26 | Yes | - |
PSMB7 | 5695 | 118 | 0.982 | 0.934 | 90 | Yes | - |
HNRNPC | 3183 | 108 | 1.812 | 0.973 | 181 | Yes | - |
PSMA1 | 5682 | 100 | 0.996 | 0.878 | 152 | Yes | - |
VARS | 7407 | 86 | 0.549 | 1.002 | 204 | Yes | - |
TREX1 | 11277 | 51 | -0.051 | 0.882 | 91 | Yes | - |
DDX51 | 317781 | 53 | 0.059 | 0.823 | 210 | Yes | - |
POLE4 | 56655 | 63 | 0.177 | 0.828 | 56 | - | - |
PSMB3 | 5691 | 64 | 0.668 | 0.901 | 19 | Yes | - |
RPA1 | 6117 | 51 | 0.425 | 0.865 | 74 | - | - |
CAD | 790 | 91 | 0.807 | 0.973 | 400 | - | - |
EIF6 | 3692 | 67 | 0.700 | 0.876 | 316 | Yes | - |
PSMD1 | 5707 | 86 | 0.836 | 0.830 | 118 | Yes | - |
RUVBL1 | 8607 | 95 | 0.720 | 0.973 | 469 | Yes | - |
PSMD3 | 5709 | 100 | 0.986 | 1.106 | 201 | Yes | - |
EFTUD2 | 9343 | 93 | 0.883 | 0.956 | 108 | Yes | - |
PSMD14 | 10213 | 44 | 0.299 | 0.815 | 32 | - | - |
PSMB2 | 5690 | 116 | 0.877 | 0.956 | 169 | Yes | - |
TUBG1 | 7283 | 98 | 0.974 | 0.973 | 91 | Yes | - |
PSMD11 | 5717 | 124 | 1.095 | 1.106 | 218 | Yes | - |
ACTB | 60 | 134 | 1.153 | 1.151 | 610 | Yes | - |
RAN | 5901 | 89 | 0.632 | 0.899 | 258 | Yes | - |
RUVBL2 | 10856 | 95 | 0.693 | 0.956 | 532 | Yes | - |
PRMT3 | 10196 | 49 | 0.431 | 0.815 | 26 | - | - |
MTHFD1 | 4522 | 49 | 0.194 | 0.815 | 26 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
PSMA3 | 5684 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core |
HNRNPC | 3183 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
PSMA1 | 5682 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
PSMD11 | 5717 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
PSMA1 | 5682 | PSMB1 | 5689 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd |
EFTUD2 | 9343 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
EFTUD2 | 9343 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid |
CAD | 790 | RPA1 | 6117 | pd | < | reg.ITFP.txt: no annot |
MTHFD1 | 4522 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid |
PSMB2 | 5690 | TREX1 | 11277 | pd | < | reg.ITFP.txt: no annot |
PSMD1 | 5707 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core |
ACTB | 60 | RUVBL1 | 8607 | pp | -- | int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
PSMB3 | 5691 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
RPA1 | 6117 | RUVBL1 | 8607 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow |
RPA1 | 6117 | VARS | 7407 | pp | -- | int.I2D: YeastLow |
CAD | 790 | TREX1 | 11277 | pd | < | reg.ITFP.txt: no annot |
PSMB1 | 5689 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
RAN | 5901 | RUVBL1 | 8607 | pd | < | reg.ITFP.txt: no annot |
PSMB1 | 5689 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
PSMB2 | 5690 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMB3 | 5691 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast |
CAD | 790 | RUVBL1 | 8607 | pd | < | reg.ITFP.txt: no annot |
CAD | 790 | RUVBL1 | 8607 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
RPA1 | 6117 | TREX1 | 11277 | pp | -- | int.I2D: BCI; int.HPRD: in vitro |
PSMA3 | 5684 | PSMD14 | 10213 | pd | < | reg.ITFP.txt: no annot |
PSMA3 | 5684 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
RPA1 | 6117 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
PSMB1 | 5689 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB1 | 5689 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast; int.Mint: MI:0915(physical association) |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
TREX1 | 11277 | DDX51 | 317781 | pd | <> | reg.ITFP.txt: no annot |
PSMA1 | 5682 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0914(association); int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
PSMD1 | 5707 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMD14 | 10213 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
TUBG1 | 7283 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
ACTB | 60 | PSMA3 | 5684 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast |
RUVBL1 | 8607 | RUVBL2 | 10856 | pd | <> | reg.ITFP.txt: no annot |
RUVBL1 | 8607 | RUVBL2 | 10856 | pp | -- | int.Proteinpedia: Mass spectrometry; int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd; int.Ravasi: -; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association) |
PSMA1 | 5682 | PSMD14 | 10213 | pd | < | reg.ITFP.txt: no annot |
PSMA1 | 5682 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast, BioGrid, YeastMedium |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
MTHFD1 | 4522 | PRMT3 | 10196 | pd | < | reg.ITFP.txt: no annot |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | CAD | 790 | pp | -- | int.I2D: IntAct_Yeast |
PSMD1 | 5707 | PSMD14 | 10213 | pd | < | reg.ITFP.txt: no annot |
PSMD1 | 5707 | PSMD14 | 10213 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast |
PSMA1 | 5682 | RPA1 | 6117 | pd | < | reg.ITFP.txt: no annot |
PSMB7 | 5695 | RBX1 | 9978 | pd | < | reg.ITFP.txt: no annot |
PSMA3 | 5684 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
CAD | 790 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
CAD | 790 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
HNRNPC | 3183 | RUVBL1 | 8607 | pd | < | reg.ITFP.txt: no annot |
PSMD3 | 5709 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
VARS | 7407 | POLE4 | 56655 | pd | <> | reg.ITFP.txt: no annot |
PSMA2 | 5683 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd |
PSMD3 | 5709 | TUBG1 | 7283 | pd | > | reg.ITFP.txt: no annot |
PSMD11 | 5717 | PSMD14 | 10213 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct, INTEROLOG |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
CAD | 790 | DDX51 | 317781 | pp | -- | int.I2D: IntAct_Yeast |
VARS | 7407 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast |
HNRNPC | 3183 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
PSMA2 | 5683 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMB1 | 5689 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
VARS | 7407 | RUVBL1 | 8607 | pd | <> | reg.ITFP.txt: no annot |
PSMA3 | 5684 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid, BioGrid_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA3 | 5684 | EFTUD2 | 9343 | pp | -- | int.I2D: BioGrid |
PSMB2 | 5690 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
PSMB7 | 5695 | DDX51 | 317781 | pd | < | reg.ITFP.txt: no annot |
PSMB7 | 5695 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMA3 | 5684 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core |
MTHFD1 | 4522 | RUVBL1 | 8607 | pd | < | reg.ITFP.txt: no annot |
MTHFD1 | 4522 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
MTHFD1 | 4522 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct |
TUBG1 | 7283 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
CAD | 790 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA3 | 5684 | RUVBL1 | 8607 | pp | -- | int.I2D: BioGrid |
PSMB7 | 5695 | PSMD14 | 10213 | pd | < | reg.ITFP.txt: no annot |
PSMB7 | 5695 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | RAN | 5901 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, NON_CORE |
RAN | 5901 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
TUBG1 | 7283 | RUVBL1 | 8607 | pd | < | reg.ITFP.txt: no annot |
POLR2F | 5435 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
CAD | 790 | RAN | 5901 | pp | -- | int.I2D: IntAct_Yeast |
PSMB3 | 5691 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS; int.HPRD: yeast 2-hybrid |
PSMB2 | 5690 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
MTHFD1 | 4522 | RPA1 | 6117 | pd | < | reg.ITFP.txt: no annot |
VARS | 7407 | DDX51 | 317781 | pd | <> | reg.ITFP.txt: no annot |
RUVBL1 | 8607 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast |
PSMD3 | 5709 | VARS | 7407 | pd | <> | reg.ITFP.txt: no annot |
PSMB7 | 5695 | PSMD1 | 5707 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct |
PSMA1 | 5682 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0914(association), MI:0915(physical association); int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd; int.HPRD: in vitro |
PSMB7 | 5695 | TREX1 | 11277 | pd | < | reg.ITFP.txt: no annot |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMD11 | 5717 | TUBG1 | 7283 | pd | > | reg.ITFP.txt: no annot |
PSMA2 | 5683 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA1 | 5682 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.Mint: MI:0915(physical association); int.HPRD: yeast 2-hybrid |
PSMB1 | 5689 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
MTHFD1 | 4522 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast |
CAD | 790 | PSMB2 | 5690 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | DDX51 | 317781 | pd | < | reg.ITFP.txt: no annot |
PSMD11 | 5717 | EFTUD2 | 9343 | pd | > | reg.ITFP.txt: no annot |
PSMD11 | 5717 | RUVBL2 | 10856 | pp | -- | int.I2D: YeastLow |
PSMB3 | 5691 | POLE4 | 56655 | pd | < | reg.ITFP.txt: no annot |
PSMA3 | 5684 | PSMB1 | 5689 | pp | -- | int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, IntAct_Yeast, YeastHigh |
VARS | 7407 | RUVBL2 | 10856 | pd | <> | reg.ITFP.txt: no annot |
PSMB1 | 5689 | RUVBL2 | 10856 | pd | < | reg.ITFP.txt: no annot |
PSMD1 | 5707 | RUVBL2 | 10856 | pp | -- | int.I2D: IntAct_Yeast |
PSMA3 | 5684 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast |
PSMB1 | 5689 | TREX1 | 11277 | pd | < | reg.ITFP.txt: no annot |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMA3 | 5684 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMD11 | 5717 | pd | < | reg.ITFP.txt: no annot |
PSMB2 | 5690 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB2 | 5690 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
EIF6 | 3692 | PSMB1 | 5689 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMA2 | 5683 | PSMB1 | 5689 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh |
ACTB | 60 | RPA1 | 6117 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
PSMD14 | 10213 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PSMB3 | 5691 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
PSMD3 | 5709 | PSMD14 | 10213 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh |
PSMB7 | 5695 | RPA1 | 6117 | pd | < | reg.ITFP.txt: no annot |
EIF6 | 3692 | DDX51 | 317781 | pd | < | reg.ITFP.txt: no annot |
EIF6 | 3692 | PSMB3 | 5691 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
RAN | 5901 | TREX1 | 11277 | pd | < | reg.ITFP.txt: no annot |
RUVBL2 | 10856 | TREX1 | 11277 | pd | <> | reg.ITFP.txt: no annot |
ACTB | 60 | RUVBL2 | 10856 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid |
PSMA2 | 5683 | PSMA3 | 5684 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD; int.HPRD: yeast 2-hybrid |
PSMA3 | 5684 | PSMB3 | 5691 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
POLR2F | 5435 | VARS | 7407 | pd | < | reg.ITFP.txt: no annot |
ACTB | 60 | PSMD14 | 10213 | pp | -- | int.I2D: BioGrid_Yeast |
PSMB2 | 5690 | PSMD1 | 5707 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMB2 | 5690 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core |
EIF6 | 3692 | RUVBL1 | 8607 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0006521 | regulation of cellular amino acid metabolic process | 2.27e-21 | 3.71e-17 | 6.952 | 11 | 21 | 50 |
GO:0000502 | proteasome complex | 1.37e-20 | 2.24e-16 | 6.738 | 11 | 22 | 58 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.36e-20 | 8.76e-16 | 6.574 | 11 | 24 | 65 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 5.36e-20 | 8.76e-16 | 6.574 | 11 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 1.29e-19 | 2.11e-15 | 6.467 | 11 | 24 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 2.12e-19 | 3.45e-15 | 6.406 | 11 | 23 | 73 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.48e-19 | 4.05e-15 | 6.386 | 11 | 24 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 3.96e-19 | 6.46e-15 | 6.329 | 11 | 23 | 77 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 5.34e-19 | 8.72e-15 | 6.292 | 11 | 25 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 4.02e-18 | 6.56e-14 | 6.041 | 11 | 23 | 94 |
GO:0000082 | G1/S transition of mitotic cell cycle | 1.05e-17 | 1.72e-13 | 5.493 | 12 | 33 | 150 |
GO:0005654 | nucleoplasm | 1.62e-17 | 2.65e-13 | 3.362 | 20 | 83 | 1095 |
GO:0000209 | protein polyubiquitination | 4.47e-17 | 7.30e-13 | 5.738 | 11 | 21 | 116 |
GO:0005839 | proteasome core complex | 8.02e-16 | 1.31e-11 | 7.774 | 7 | 11 | 18 |
GO:0042981 | regulation of apoptotic process | 8.82e-16 | 1.44e-11 | 5.357 | 11 | 26 | 151 |
GO:0004298 | threonine-type endopeptidase activity | 1.95e-15 | 3.18e-11 | 7.622 | 7 | 11 | 20 |
GO:0010467 | gene expression | 2.20e-15 | 3.59e-11 | 3.751 | 16 | 58 | 669 |
GO:0034641 | cellular nitrogen compound metabolic process | 5.21e-15 | 8.51e-11 | 5.128 | 11 | 25 | 177 |
GO:0000278 | mitotic cell cycle | 4.23e-14 | 6.91e-10 | 4.200 | 13 | 52 | 398 |
GO:0016071 | mRNA metabolic process | 6.75e-14 | 1.10e-09 | 4.795 | 11 | 34 | 223 |
GO:0016032 | viral process | 7.84e-14 | 1.28e-09 | 3.867 | 14 | 55 | 540 |
GO:0016070 | RNA metabolic process | 2.08e-13 | 3.39e-09 | 4.648 | 11 | 34 | 247 |
GO:0005829 | cytosol | 9.51e-13 | 1.55e-08 | 2.273 | 22 | 125 | 2562 |
GO:0043066 | negative regulation of apoptotic process | 9.09e-11 | 1.48e-06 | 3.838 | 11 | 30 | 433 |
GO:0070062 | extracellular vesicular exosome | 1.47e-09 | 2.39e-05 | 2.087 | 19 | 98 | 2516 |
GO:0006915 | apoptotic process | 1.70e-09 | 2.78e-05 | 3.439 | 11 | 34 | 571 |
GO:0044281 | small molecule metabolic process | 9.12e-09 | 1.49e-04 | 2.605 | 14 | 57 | 1295 |
GO:0022624 | proteasome accessory complex | 1.88e-08 | 3.07e-04 | 7.049 | 4 | 9 | 17 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 2.81e-07 | 4.58e-03 | 7.721 | 3 | 5 | 8 |
GO:0005838 | proteasome regulatory particle | 1.10e-06 | 1.79e-02 | 7.136 | 3 | 7 | 12 |
GO:0035267 | NuA4 histone acetyltransferase complex | 1.81e-06 | 2.96e-02 | 6.914 | 3 | 4 | 14 |
GO:0005730 | nucleolus | 1.99e-06 | 3.24e-02 | 2.119 | 13 | 70 | 1684 |
GO:0005634 | nucleus | 2.32e-06 | 3.79e-02 | 1.292 | 21 | 131 | 4828 |
GO:0016020 | membrane | 2.99e-06 | 4.89e-02 | 2.067 | 13 | 80 | 1746 |
GO:0006310 | DNA recombination | 5.70e-06 | 9.31e-02 | 5.070 | 4 | 4 | 67 |
GO:0006281 | DNA repair | 5.88e-06 | 9.60e-02 | 3.677 | 6 | 22 | 264 |
GO:0000812 | Swr1 complex | 8.48e-05 | 1.00e+00 | 7.136 | 2 | 3 | 8 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 1.18e-04 | 1.00e+00 | 4.967 | 3 | 5 | 54 |
GO:0043968 | histone H2A acetylation | 1.99e-04 | 1.00e+00 | 6.551 | 2 | 3 | 12 |
GO:0030234 | enzyme regulator activity | 2.35e-04 | 1.00e+00 | 6.436 | 2 | 3 | 13 |
GO:0031011 | Ino80 complex | 2.74e-04 | 1.00e+00 | 6.329 | 2 | 3 | 14 |
GO:0042176 | regulation of protein catabolic process | 3.60e-04 | 1.00e+00 | 6.136 | 2 | 3 | 16 |
GO:0006259 | DNA metabolic process | 5.12e-04 | 1.00e+00 | 5.889 | 2 | 3 | 19 |
GO:0003678 | DNA helicase activity | 5.12e-04 | 1.00e+00 | 5.889 | 2 | 3 | 19 |
GO:0006298 | mismatch repair | 5.68e-04 | 1.00e+00 | 5.815 | 2 | 6 | 20 |
GO:0016363 | nuclear matrix | 5.70e-04 | 1.00e+00 | 4.198 | 3 | 11 | 92 |
GO:0005515 | protein binding | 5.88e-04 | 1.00e+00 | 0.877 | 20 | 172 | 6127 |
GO:0043044 | ATP-dependent chromatin remodeling | 7.54e-04 | 1.00e+00 | 5.613 | 2 | 4 | 23 |
GO:0071339 | MLL1 complex | 1.04e-03 | 1.00e+00 | 5.382 | 2 | 3 | 27 |
GO:0030529 | ribonucleoprotein complex | 1.06e-03 | 1.00e+00 | 3.889 | 3 | 8 | 114 |
GO:0043967 | histone H4 acetylation | 1.12e-03 | 1.00e+00 | 5.329 | 2 | 3 | 28 |
GO:0031492 | nucleosomal DNA binding | 1.12e-03 | 1.00e+00 | 5.329 | 2 | 4 | 28 |
GO:0006325 | chromatin organization | 1.32e-03 | 1.00e+00 | 3.779 | 3 | 4 | 123 |
GO:0004088 | carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity | 1.78e-03 | 1.00e+00 | 9.136 | 1 | 1 | 1 |
GO:0070335 | aspartate binding | 1.78e-03 | 1.00e+00 | 9.136 | 1 | 1 | 1 |
GO:0008541 | proteasome regulatory particle, lid subcomplex | 1.78e-03 | 1.00e+00 | 9.136 | 1 | 1 | 1 |
GO:0032558 | adenyl deoxyribonucleotide binding | 1.78e-03 | 1.00e+00 | 9.136 | 1 | 1 | 1 |
GO:0004151 | dihydroorotase activity | 1.78e-03 | 1.00e+00 | 9.136 | 1 | 1 | 1 |
GO:0000054 | ribosomal subunit export from nucleus | 1.78e-03 | 1.00e+00 | 9.136 | 1 | 1 | 1 |
GO:0004070 | aspartate carbamoyltransferase activity | 1.78e-03 | 1.00e+00 | 9.136 | 1 | 1 | 1 |
GO:0004486 | methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity | 1.78e-03 | 1.00e+00 | 9.136 | 1 | 1 | 1 |
GO:0032508 | DNA duplex unwinding | 2.51e-03 | 1.00e+00 | 4.744 | 2 | 4 | 42 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 3.01e-03 | 1.00e+00 | 4.613 | 2 | 8 | 46 |
GO:0000398 | mRNA splicing, via spliceosome | 3.06e-03 | 1.00e+00 | 3.355 | 3 | 12 | 165 |
GO:0004832 | valine-tRNA ligase activity | 3.55e-03 | 1.00e+00 | 8.136 | 1 | 1 | 2 |
GO:0006438 | valyl-tRNA aminoacylation | 3.55e-03 | 1.00e+00 | 8.136 | 1 | 1 | 2 |
GO:0000105 | histidine biosynthetic process | 3.55e-03 | 1.00e+00 | 8.136 | 1 | 1 | 2 |
GO:0008296 | 3'-5'-exodeoxyribonuclease activity | 3.55e-03 | 1.00e+00 | 8.136 | 1 | 1 | 2 |
GO:0070409 | carbamoyl phosphate biosynthetic process | 3.55e-03 | 1.00e+00 | 8.136 | 1 | 1 | 2 |
GO:0040008 | regulation of growth | 3.68e-03 | 1.00e+00 | 4.464 | 2 | 3 | 51 |
GO:0003684 | damaged DNA binding | 3.68e-03 | 1.00e+00 | 4.464 | 2 | 11 | 51 |
GO:0000724 | double-strand break repair via homologous recombination | 4.58e-03 | 1.00e+00 | 4.304 | 2 | 6 | 57 |
GO:0032481 | positive regulation of type I interferon production | 5.23e-03 | 1.00e+00 | 4.206 | 2 | 6 | 61 |
GO:0071899 | negative regulation of estrogen receptor binding | 5.32e-03 | 1.00e+00 | 7.551 | 1 | 1 | 3 |
GO:0071733 | transcriptional activation by promoter-enhancer looping | 5.32e-03 | 1.00e+00 | 7.551 | 1 | 1 | 3 |
GO:0000056 | ribosomal small subunit export from nucleus | 5.32e-03 | 1.00e+00 | 7.551 | 1 | 1 | 3 |
GO:0044205 | 'de novo' UMP biosynthetic process | 5.32e-03 | 1.00e+00 | 7.551 | 1 | 1 | 3 |
GO:0006207 | 'de novo' pyrimidine nucleobase biosynthetic process | 5.32e-03 | 1.00e+00 | 7.551 | 1 | 1 | 3 |
GO:0003924 | GTPase activity | 5.46e-03 | 1.00e+00 | 3.056 | 3 | 9 | 203 |
GO:0006289 | nucleotide-excision repair | 6.64e-03 | 1.00e+00 | 4.028 | 2 | 12 | 69 |
GO:0003697 | single-stranded DNA binding | 6.64e-03 | 1.00e+00 | 4.028 | 2 | 9 | 69 |
GO:0006184 | GTP catabolic process | 6.82e-03 | 1.00e+00 | 2.940 | 3 | 9 | 220 |
GO:0000212 | meiotic spindle organization | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0016274 | protein-arginine N-methyltransferase activity | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0004488 | methylenetetrahydrofolate dehydrogenase (NADP+) activity | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0004329 | formate-tetrahydrofolate ligase activity | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0043141 | ATP-dependent 5'-3' DNA helicase activity | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0034969 | histone arginine methylation | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0006543 | glutamine catabolic process | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0009396 | folic acid-containing compound biosynthetic process | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0004477 | methenyltetrahydrofolate cyclohydrolase activity | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0000055 | ribosomal large subunit export from nucleus | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0008853 | exodeoxyribonuclease III activity | 7.09e-03 | 1.00e+00 | 7.136 | 1 | 1 | 4 |
GO:0008380 | RNA splicing | 7.89e-03 | 1.00e+00 | 2.863 | 3 | 13 | 232 |
GO:0005524 | ATP binding | 8.18e-03 | 1.00e+00 | 1.541 | 7 | 46 | 1354 |
GO:0071013 | catalytic step 2 spliceosome | 8.63e-03 | 1.00e+00 | 3.833 | 2 | 7 | 79 |
GO:0051414 | response to cortisol | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 2 | 5 |
GO:0042256 | mature ribosome assembly | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0009086 | methionine biosynthetic process | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0032407 | MutSalpha complex binding | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0008622 | epsilon DNA polymerase complex | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0071169 | establishment of protein localization to chromatin | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 2 | 5 |
GO:0005827 | polar microtubule | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0000730 | DNA recombinase assembly | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 3 | 5 |
GO:0005638 | lamin filament | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0061133 | endopeptidase activator activity | 8.85e-03 | 1.00e+00 | 6.815 | 1 | 1 | 5 |
GO:0005681 | spliceosomal complex | 9.49e-03 | 1.00e+00 | 3.761 | 2 | 3 | 83 |
GO:0043023 | ribosomal large subunit binding | 1.06e-02 | 1.00e+00 | 6.551 | 1 | 2 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 1.06e-02 | 1.00e+00 | 6.551 | 1 | 1 | 6 |
GO:0030957 | Tat protein binding | 1.06e-02 | 1.00e+00 | 6.551 | 1 | 4 | 6 |
GO:0046134 | pyrimidine nucleoside biosynthetic process | 1.06e-02 | 1.00e+00 | 6.551 | 1 | 1 | 6 |
GO:0032405 | MutLalpha complex binding | 1.06e-02 | 1.00e+00 | 6.551 | 1 | 2 | 6 |
GO:0008469 | histone-arginine N-methyltransferase activity | 1.06e-02 | 1.00e+00 | 6.551 | 1 | 1 | 6 |
GO:0005200 | structural constituent of cytoskeleton | 1.18e-02 | 1.00e+00 | 3.597 | 2 | 7 | 93 |
GO:0010950 | positive regulation of endopeptidase activity | 1.24e-02 | 1.00e+00 | 6.329 | 1 | 1 | 7 |
GO:0002161 | aminoacyl-tRNA editing activity | 1.24e-02 | 1.00e+00 | 6.329 | 1 | 2 | 7 |
GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity | 1.24e-02 | 1.00e+00 | 6.329 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 1.24e-02 | 1.00e+00 | 6.329 | 1 | 2 | 7 |
GO:0035999 | tetrahydrofolate interconversion | 1.24e-02 | 1.00e+00 | 6.329 | 1 | 1 | 7 |
GO:0072341 | modified amino acid binding | 1.24e-02 | 1.00e+00 | 6.329 | 1 | 1 | 7 |
GO:0000930 | gamma-tubulin complex | 1.24e-02 | 1.00e+00 | 6.329 | 1 | 1 | 7 |
GO:0019919 | peptidyl-arginine methylation, to asymmetrical-dimethyl arginine | 1.24e-02 | 1.00e+00 | 6.329 | 1 | 1 | 7 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 1.41e-02 | 1.00e+00 | 6.136 | 1 | 2 | 8 |
GO:0001055 | RNA polymerase II activity | 1.41e-02 | 1.00e+00 | 6.136 | 1 | 3 | 8 |
GO:0070688 | MLL5-L complex | 1.41e-02 | 1.00e+00 | 6.136 | 1 | 1 | 8 |
GO:0045116 | protein neddylation | 1.41e-02 | 1.00e+00 | 6.136 | 1 | 2 | 8 |
GO:0000800 | lateral element | 1.41e-02 | 1.00e+00 | 6.136 | 1 | 1 | 8 |
GO:0006164 | purine nucleotide biosynthetic process | 1.41e-02 | 1.00e+00 | 6.136 | 1 | 2 | 8 |
GO:0043234 | protein complex | 1.58e-02 | 1.00e+00 | 2.493 | 3 | 17 | 300 |
GO:0014075 | response to amine | 1.59e-02 | 1.00e+00 | 5.967 | 1 | 1 | 9 |
GO:0006228 | UTP biosynthetic process | 1.59e-02 | 1.00e+00 | 5.967 | 1 | 1 | 9 |
GO:0031000 | response to caffeine | 1.59e-02 | 1.00e+00 | 5.967 | 1 | 2 | 9 |
GO:0070628 | proteasome binding | 1.76e-02 | 1.00e+00 | 5.815 | 1 | 1 | 10 |
GO:0046655 | folic acid metabolic process | 1.76e-02 | 1.00e+00 | 5.815 | 1 | 1 | 10 |
GO:0006450 | regulation of translational fidelity | 1.76e-02 | 1.00e+00 | 5.815 | 1 | 2 | 10 |
GO:0001054 | RNA polymerase I activity | 1.94e-02 | 1.00e+00 | 5.677 | 1 | 3 | 11 |
GO:0045120 | pronucleus | 1.94e-02 | 1.00e+00 | 5.677 | 1 | 1 | 11 |
GO:0035458 | cellular response to interferon-beta | 1.94e-02 | 1.00e+00 | 5.677 | 1 | 2 | 11 |
GO:0005525 | GTP binding | 2.00e-02 | 1.00e+00 | 2.364 | 3 | 11 | 328 |
GO:0006260 | DNA replication | 2.06e-02 | 1.00e+00 | 3.171 | 2 | 12 | 125 |
GO:0061136 | regulation of proteasomal protein catabolic process | 2.11e-02 | 1.00e+00 | 5.551 | 1 | 1 | 12 |
GO:0070935 | 3'-UTR-mediated mRNA stabilization | 2.11e-02 | 1.00e+00 | 5.551 | 1 | 2 | 12 |
GO:0005736 | DNA-directed RNA polymerase I complex | 2.11e-02 | 1.00e+00 | 5.551 | 1 | 3 | 12 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 2.13e-02 | 1.00e+00 | 3.148 | 2 | 5 | 127 |
GO:0042273 | ribosomal large subunit biogenesis | 2.29e-02 | 1.00e+00 | 5.436 | 1 | 4 | 13 |
GO:0032479 | regulation of type I interferon production | 2.29e-02 | 1.00e+00 | 5.436 | 1 | 2 | 13 |
GO:0005662 | DNA replication factor A complex | 2.29e-02 | 1.00e+00 | 5.436 | 1 | 3 | 13 |
GO:0000738 | DNA catabolic process, exonucleolytic | 2.29e-02 | 1.00e+00 | 5.436 | 1 | 2 | 13 |
GO:0008266 | poly(U) RNA binding | 2.29e-02 | 1.00e+00 | 5.436 | 1 | 1 | 13 |
GO:0000790 | nuclear chromatin | 2.32e-02 | 1.00e+00 | 3.081 | 2 | 7 | 133 |
GO:0007020 | microtubule nucleation | 2.46e-02 | 1.00e+00 | 5.329 | 1 | 1 | 14 |
GO:0035066 | positive regulation of histone acetylation | 2.63e-02 | 1.00e+00 | 5.230 | 1 | 1 | 15 |
GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex | 2.63e-02 | 1.00e+00 | 5.230 | 1 | 1 | 15 |
GO:0006261 | DNA-dependent DNA replication | 2.63e-02 | 1.00e+00 | 5.230 | 1 | 2 | 15 |
GO:0016887 | ATPase activity | 2.69e-02 | 1.00e+00 | 2.967 | 2 | 7 | 144 |
GO:0005665 | DNA-directed RNA polymerase II, core complex | 2.81e-02 | 1.00e+00 | 5.136 | 1 | 4 | 16 |
GO:0050998 | nitric-oxide synthase binding | 2.81e-02 | 1.00e+00 | 5.136 | 1 | 1 | 16 |
GO:0001673 | male germ cell nucleus | 2.81e-02 | 1.00e+00 | 5.136 | 1 | 1 | 16 |
GO:0001056 | RNA polymerase III activity | 2.81e-02 | 1.00e+00 | 5.136 | 1 | 3 | 16 |
GO:0008408 | 3'-5' exonuclease activity | 2.81e-02 | 1.00e+00 | 5.136 | 1 | 2 | 16 |
GO:0006457 | protein folding | 2.86e-02 | 1.00e+00 | 2.917 | 2 | 8 | 149 |
GO:0010243 | response to organonitrogen compound | 2.98e-02 | 1.00e+00 | 5.049 | 1 | 2 | 17 |
GO:0005666 | DNA-directed RNA polymerase III complex | 2.98e-02 | 1.00e+00 | 5.049 | 1 | 3 | 17 |
GO:0075733 | intracellular transport of virus | 2.98e-02 | 1.00e+00 | 5.049 | 1 | 2 | 17 |
GO:0007126 | meiotic nuclear division | 2.98e-02 | 1.00e+00 | 5.049 | 1 | 1 | 17 |
GO:0070536 | protein K63-linked deubiquitination | 3.15e-02 | 1.00e+00 | 4.967 | 1 | 1 | 18 |
GO:0006386 | termination of RNA polymerase III transcription | 3.15e-02 | 1.00e+00 | 4.967 | 1 | 3 | 18 |
GO:0071392 | cellular response to estradiol stimulus | 3.15e-02 | 1.00e+00 | 4.967 | 1 | 1 | 18 |
GO:0006541 | glutamine metabolic process | 3.15e-02 | 1.00e+00 | 4.967 | 1 | 1 | 18 |
GO:0031122 | cytoplasmic microtubule organization | 3.15e-02 | 1.00e+00 | 4.967 | 1 | 2 | 18 |
GO:0006385 | transcription elongation from RNA polymerase III promoter | 3.15e-02 | 1.00e+00 | 4.967 | 1 | 3 | 18 |
GO:0006303 | double-strand break repair via nonhomologous end joining | 3.15e-02 | 1.00e+00 | 4.967 | 1 | 3 | 18 |
GO:0005737 | cytoplasm | 3.23e-02 | 1.00e+00 | 0.764 | 12 | 98 | 3976 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 3.32e-02 | 1.00e+00 | 4.889 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 3.32e-02 | 1.00e+00 | 4.889 | 1 | 1 | 19 |
GO:0048873 | homeostasis of number of cells within a tissue | 3.50e-02 | 1.00e+00 | 4.815 | 1 | 1 | 20 |
GO:0005719 | nuclear euchromatin | 3.50e-02 | 1.00e+00 | 4.815 | 1 | 2 | 20 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 3.57e-02 | 1.00e+00 | 2.744 | 2 | 5 | 168 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 3.67e-02 | 1.00e+00 | 4.744 | 1 | 5 | 21 |
GO:0071364 | cellular response to epidermal growth factor stimulus | 3.67e-02 | 1.00e+00 | 4.744 | 1 | 1 | 21 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 3.84e-02 | 1.00e+00 | 4.677 | 1 | 5 | 22 |
GO:0033574 | response to testosterone | 3.84e-02 | 1.00e+00 | 4.677 | 1 | 2 | 22 |
GO:0032201 | telomere maintenance via semi-conservative replication | 3.84e-02 | 1.00e+00 | 4.677 | 1 | 7 | 22 |
GO:0030863 | cortical cytoskeleton | 3.84e-02 | 1.00e+00 | 4.677 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 3.84e-02 | 1.00e+00 | 4.677 | 1 | 4 | 22 |
GO:0007052 | mitotic spindle organization | 3.84e-02 | 1.00e+00 | 4.677 | 1 | 2 | 22 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 4.01e-02 | 1.00e+00 | 4.613 | 1 | 2 | 23 |
GO:0006513 | protein monoubiquitination | 4.01e-02 | 1.00e+00 | 4.613 | 1 | 1 | 23 |
GO:0015629 | actin cytoskeleton | 4.16e-02 | 1.00e+00 | 2.621 | 2 | 5 | 183 |
GO:0000794 | condensed nuclear chromosome | 4.18e-02 | 1.00e+00 | 4.551 | 1 | 2 | 24 |
GO:0006206 | pyrimidine nucleobase metabolic process | 4.18e-02 | 1.00e+00 | 4.551 | 1 | 2 | 24 |
GO:0006611 | protein export from nucleus | 4.35e-02 | 1.00e+00 | 4.493 | 1 | 4 | 25 |
GO:0005844 | polysome | 4.35e-02 | 1.00e+00 | 4.493 | 1 | 4 | 25 |
GO:0017144 | drug metabolic process | 4.35e-02 | 1.00e+00 | 4.493 | 1 | 1 | 25 |
GO:0000722 | telomere maintenance via recombination | 4.52e-02 | 1.00e+00 | 4.436 | 1 | 7 | 26 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 4.52e-02 | 1.00e+00 | 4.436 | 1 | 2 | 26 |
GO:0006730 | one-carbon metabolic process | 4.52e-02 | 1.00e+00 | 4.436 | 1 | 1 | 26 |
GO:0004003 | ATP-dependent DNA helicase activity | 4.69e-02 | 1.00e+00 | 4.382 | 1 | 3 | 27 |
GO:0034080 | CENP-A containing nucleosome assembly | 4.69e-02 | 1.00e+00 | 4.382 | 1 | 2 | 27 |
GO:0043022 | ribosome binding | 4.86e-02 | 1.00e+00 | 4.329 | 1 | 3 | 28 |
GO:0019894 | kinesin binding | 4.86e-02 | 1.00e+00 | 4.329 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 5.03e-02 | 1.00e+00 | 4.278 | 1 | 1 | 29 |
GO:0003730 | mRNA 3'-UTR binding | 5.03e-02 | 1.00e+00 | 4.278 | 1 | 2 | 29 |
GO:0003887 | DNA-directed DNA polymerase activity | 5.03e-02 | 1.00e+00 | 4.278 | 1 | 3 | 29 |
GO:0071897 | DNA biosynthetic process | 5.03e-02 | 1.00e+00 | 4.278 | 1 | 2 | 29 |
GO:0006370 | 7-methylguanosine mRNA capping | 5.20e-02 | 1.00e+00 | 4.230 | 1 | 4 | 30 |
GO:0006360 | transcription from RNA polymerase I promoter | 5.20e-02 | 1.00e+00 | 4.230 | 1 | 4 | 30 |
GO:0006271 | DNA strand elongation involved in DNA replication | 5.37e-02 | 1.00e+00 | 4.182 | 1 | 9 | 31 |
GO:0031397 | negative regulation of protein ubiquitination | 5.54e-02 | 1.00e+00 | 4.136 | 1 | 1 | 32 |
GO:0034644 | cellular response to UV | 5.54e-02 | 1.00e+00 | 4.136 | 1 | 5 | 32 |
GO:0042802 | identical protein binding | 5.55e-02 | 1.00e+00 | 1.782 | 3 | 18 | 491 |
GO:0034332 | adherens junction organization | 6.21e-02 | 1.00e+00 | 3.967 | 1 | 1 | 36 |
GO:0004221 | ubiquitin thiolesterase activity | 6.21e-02 | 1.00e+00 | 3.967 | 1 | 2 | 36 |
GO:0001895 | retina homeostasis | 6.21e-02 | 1.00e+00 | 3.967 | 1 | 1 | 36 |
GO:0007067 | mitotic nuclear division | 6.31e-02 | 1.00e+00 | 2.285 | 2 | 13 | 231 |
GO:0051084 | 'de novo' posttranslational protein folding | 6.38e-02 | 1.00e+00 | 3.927 | 1 | 4 | 37 |
GO:0018107 | peptidyl-threonine phosphorylation | 6.38e-02 | 1.00e+00 | 3.927 | 1 | 1 | 37 |
GO:0070527 | platelet aggregation | 6.54e-02 | 1.00e+00 | 3.889 | 1 | 2 | 38 |
GO:0050681 | androgen receptor binding | 6.54e-02 | 1.00e+00 | 3.889 | 1 | 4 | 38 |
GO:0006383 | transcription from RNA polymerase III promoter | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 3 | 39 |
GO:0008026 | ATP-dependent helicase activity | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 3 | 39 |
GO:0031490 | chromatin DNA binding | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 2 | 39 |
GO:0006284 | base-excision repair | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 7 | 39 |
GO:0032092 | positive regulation of protein binding | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 3 | 39 |
GO:0007595 | lactation | 6.71e-02 | 1.00e+00 | 3.851 | 1 | 2 | 39 |
GO:0043195 | terminal bouton | 7.04e-02 | 1.00e+00 | 3.779 | 1 | 1 | 41 |
GO:0030521 | androgen receptor signaling pathway | 7.04e-02 | 1.00e+00 | 3.779 | 1 | 2 | 41 |
GO:0006418 | tRNA aminoacylation for protein translation | 7.21e-02 | 1.00e+00 | 3.744 | 1 | 5 | 42 |
GO:0014070 | response to organic cyclic compound | 7.37e-02 | 1.00e+00 | 3.710 | 1 | 3 | 43 |
GO:0007286 | spermatid development | 7.54e-02 | 1.00e+00 | 3.677 | 1 | 1 | 44 |
GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding | 7.54e-02 | 1.00e+00 | 3.677 | 1 | 2 | 44 |
GO:0050434 | positive regulation of viral transcription | 7.54e-02 | 1.00e+00 | 3.677 | 1 | 5 | 44 |
GO:0015030 | Cajal body | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 2 | 45 |
GO:0043966 | histone H3 acetylation | 7.70e-02 | 1.00e+00 | 3.645 | 1 | 2 | 45 |
GO:0021762 | substantia nigra development | 7.87e-02 | 1.00e+00 | 3.613 | 1 | 1 | 46 |
GO:0019003 | GDP binding | 8.19e-02 | 1.00e+00 | 3.551 | 1 | 2 | 48 |
GO:0003743 | translation initiation factor activity | 8.36e-02 | 1.00e+00 | 3.522 | 1 | 4 | 49 |
GO:0031100 | organ regeneration | 8.52e-02 | 1.00e+00 | 3.493 | 1 | 4 | 50 |
GO:0035690 | cellular response to drug | 8.52e-02 | 1.00e+00 | 3.493 | 1 | 2 | 50 |
GO:0008168 | methyltransferase activity | 8.85e-02 | 1.00e+00 | 3.436 | 1 | 1 | 52 |
GO:0090305 | nucleic acid phosphodiester bond hydrolysis | 9.17e-02 | 1.00e+00 | 3.382 | 1 | 2 | 54 |
GO:0000226 | microtubule cytoskeleton organization | 9.33e-02 | 1.00e+00 | 3.355 | 1 | 3 | 55 |
GO:0045087 | innate immune response | 9.48e-02 | 1.00e+00 | 1.455 | 3 | 20 | 616 |
GO:0000932 | cytoplasmic mRNA processing body | 9.49e-02 | 1.00e+00 | 3.329 | 1 | 3 | 56 |
GO:0030097 | hemopoiesis | 9.82e-02 | 1.00e+00 | 3.278 | 1 | 3 | 58 |
GO:0008237 | metallopeptidase activity | 9.82e-02 | 1.00e+00 | 3.278 | 1 | 1 | 58 |
GO:0005840 | ribosome | 9.98e-02 | 1.00e+00 | 3.254 | 1 | 2 | 59 |
GO:0045216 | cell-cell junction organization | 9.98e-02 | 1.00e+00 | 3.254 | 1 | 2 | 59 |
GO:0000723 | telomere maintenance | 9.98e-02 | 1.00e+00 | 3.254 | 1 | 8 | 59 |
GO:0005643 | nuclear pore | 9.98e-02 | 1.00e+00 | 3.254 | 1 | 4 | 59 |
GO:0006200 | ATP catabolic process | 1.01e-01 | 1.00e+00 | 1.893 | 2 | 14 | 303 |
GO:0006302 | double-strand break repair | 1.05e-01 | 1.00e+00 | 3.182 | 1 | 8 | 62 |
GO:0042995 | cell projection | 1.06e-01 | 1.00e+00 | 3.159 | 1 | 6 | 63 |
GO:0006368 | transcription elongation from RNA polymerase II promoter | 1.13e-01 | 1.00e+00 | 3.070 | 1 | 6 | 67 |
GO:0006338 | chromatin remodeling | 1.14e-01 | 1.00e+00 | 3.049 | 1 | 4 | 68 |
GO:0003682 | chromatin binding | 1.18e-01 | 1.00e+00 | 1.753 | 2 | 12 | 334 |
GO:0034329 | cell junction assembly | 1.19e-01 | 1.00e+00 | 2.987 | 1 | 1 | 71 |
GO:0005813 | centrosome | 1.21e-01 | 1.00e+00 | 1.731 | 2 | 12 | 339 |
GO:0044822 | poly(A) RNA binding | 1.21e-01 | 1.00e+00 | 1.062 | 4 | 50 | 1078 |
GO:0000785 | chromatin | 1.22e-01 | 1.00e+00 | 2.947 | 1 | 5 | 73 |
GO:0055086 | nucleobase-containing small molecule metabolic process | 1.22e-01 | 1.00e+00 | 2.947 | 1 | 5 | 73 |
GO:0006767 | water-soluble vitamin metabolic process | 1.25e-01 | 1.00e+00 | 2.908 | 1 | 3 | 75 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 1.27e-01 | 1.00e+00 | 2.889 | 1 | 3 | 76 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 1.28e-01 | 1.00e+00 | 2.870 | 1 | 5 | 77 |
GO:0006766 | vitamin metabolic process | 1.30e-01 | 1.00e+00 | 2.851 | 1 | 3 | 78 |
GO:0006334 | nucleosome assembly | 1.31e-01 | 1.00e+00 | 2.833 | 1 | 4 | 79 |
GO:0003723 | RNA binding | 1.31e-01 | 1.00e+00 | 1.665 | 2 | 19 | 355 |
GO:0007565 | female pregnancy | 1.33e-01 | 1.00e+00 | 2.815 | 1 | 2 | 80 |
GO:0001889 | liver development | 1.36e-01 | 1.00e+00 | 2.779 | 1 | 3 | 82 |
GO:0003690 | double-stranded DNA binding | 1.50e-01 | 1.00e+00 | 2.629 | 1 | 4 | 91 |
GO:0016605 | PML body | 1.51e-01 | 1.00e+00 | 2.613 | 1 | 5 | 92 |
GO:0042470 | melanosome | 1.51e-01 | 1.00e+00 | 2.613 | 1 | 10 | 92 |
GO:0006928 | cellular component movement | 1.51e-01 | 1.00e+00 | 2.613 | 1 | 7 | 92 |
GO:0051082 | unfolded protein binding | 1.56e-01 | 1.00e+00 | 2.567 | 1 | 6 | 95 |
GO:0001649 | osteoblast differentiation | 1.56e-01 | 1.00e+00 | 2.567 | 1 | 6 | 95 |
GO:0006364 | rRNA processing | 1.57e-01 | 1.00e+00 | 2.551 | 1 | 5 | 96 |
GO:0071456 | cellular response to hypoxia | 1.60e-01 | 1.00e+00 | 2.522 | 1 | 4 | 98 |
GO:0014069 | postsynaptic density | 1.72e-01 | 1.00e+00 | 2.409 | 1 | 1 | 106 |
GO:0005815 | microtubule organizing center | 1.78e-01 | 1.00e+00 | 2.355 | 1 | 4 | 110 |
GO:0015630 | microtubule cytoskeleton | 1.81e-01 | 1.00e+00 | 2.329 | 1 | 5 | 112 |
GO:0019058 | viral life cycle | 1.86e-01 | 1.00e+00 | 2.291 | 1 | 10 | 115 |
GO:0005635 | nuclear envelope | 1.87e-01 | 1.00e+00 | 2.278 | 1 | 6 | 116 |
GO:0072562 | blood microparticle | 1.87e-01 | 1.00e+00 | 2.278 | 1 | 4 | 116 |
GO:0007219 | Notch signaling pathway | 2.00e-01 | 1.00e+00 | 2.171 | 1 | 4 | 125 |
GO:0006413 | translational initiation | 2.09e-01 | 1.00e+00 | 2.103 | 1 | 12 | 131 |
GO:0009615 | response to virus | 2.10e-01 | 1.00e+00 | 2.092 | 1 | 6 | 132 |
GO:0000086 | G2/M transition of mitotic cell cycle | 2.17e-01 | 1.00e+00 | 2.038 | 1 | 7 | 137 |
GO:0007507 | heart development | 2.23e-01 | 1.00e+00 | 1.997 | 1 | 5 | 141 |
GO:0061024 | membrane organization | 2.30e-01 | 1.00e+00 | 1.947 | 1 | 5 | 146 |
GO:0046777 | protein autophosphorylation | 2.46e-01 | 1.00e+00 | 1.833 | 1 | 3 | 158 |
GO:0046872 | metal ion binding | 2.60e-01 | 1.00e+00 | 0.620 | 4 | 24 | 1465 |
GO:0006397 | mRNA processing | 2.61e-01 | 1.00e+00 | 1.736 | 1 | 3 | 169 |
GO:0030424 | axon | 2.65e-01 | 1.00e+00 | 1.710 | 1 | 3 | 172 |
GO:0016607 | nuclear speck | 2.69e-01 | 1.00e+00 | 1.685 | 1 | 4 | 175 |
GO:0004672 | protein kinase activity | 2.73e-01 | 1.00e+00 | 1.661 | 1 | 2 | 178 |
GO:0031625 | ubiquitin protein ligase binding | 2.75e-01 | 1.00e+00 | 1.645 | 1 | 13 | 180 |
GO:0019904 | protein domain specific binding | 2.77e-01 | 1.00e+00 | 1.637 | 1 | 6 | 181 |
GO:0006367 | transcription initiation from RNA polymerase II promoter | 2.80e-01 | 1.00e+00 | 1.613 | 1 | 8 | 184 |
GO:0032403 | protein complex binding | 2.82e-01 | 1.00e+00 | 1.605 | 1 | 7 | 185 |
GO:0005739 | mitochondrion | 2.84e-01 | 1.00e+00 | 0.691 | 3 | 24 | 1046 |
GO:0001701 | in utero embryonic development | 3.13e-01 | 1.00e+00 | 1.422 | 1 | 6 | 210 |
GO:0005794 | Golgi apparatus | 3.22e-01 | 1.00e+00 | 0.792 | 2 | 14 | 650 |
GO:0005622 | intracellular | 3.33e-01 | 1.00e+00 | 1.316 | 1 | 5 | 226 |
GO:0003713 | transcription coactivator activity | 3.48e-01 | 1.00e+00 | 1.236 | 1 | 10 | 239 |
GO:0043025 | neuronal cell body | 3.66e-01 | 1.00e+00 | 1.148 | 1 | 4 | 254 |
GO:0004842 | ubiquitin-protein transferase activity | 3.68e-01 | 1.00e+00 | 1.136 | 1 | 4 | 256 |
GO:0000166 | nucleotide binding | 3.86e-01 | 1.00e+00 | 1.049 | 1 | 6 | 272 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 3.89e-01 | 1.00e+00 | 1.033 | 1 | 6 | 275 |
GO:0007283 | spermatogenesis | 3.90e-01 | 1.00e+00 | 1.028 | 1 | 6 | 276 |
GO:0019899 | enzyme binding | 4.04e-01 | 1.00e+00 | 0.967 | 1 | 11 | 288 |
GO:0007264 | small GTPase mediated signal transduction | 4.06e-01 | 1.00e+00 | 0.957 | 1 | 3 | 290 |
GO:0016567 | protein ubiquitination | 4.15e-01 | 1.00e+00 | 0.912 | 1 | 5 | 299 |
GO:0005856 | cytoskeleton | 4.28e-01 | 1.00e+00 | 0.856 | 1 | 8 | 311 |
GO:0019901 | protein kinase binding | 4.37e-01 | 1.00e+00 | 0.815 | 1 | 21 | 320 |
GO:0007411 | axon guidance | 4.44e-01 | 1.00e+00 | 0.783 | 1 | 9 | 327 |
GO:0043231 | intracellular membrane-bounded organelle | 4.49e-01 | 1.00e+00 | 0.761 | 1 | 8 | 332 |
GO:0043565 | sequence-specific DNA binding | 4.81e-01 | 1.00e+00 | 0.625 | 1 | 4 | 365 |
GO:0005925 | focal adhesion | 4.86e-01 | 1.00e+00 | 0.605 | 1 | 18 | 370 |
GO:0008284 | positive regulation of cell proliferation | 5.06e-01 | 1.00e+00 | 0.522 | 1 | 8 | 392 |
GO:0046982 | protein heterodimerization activity | 5.12e-01 | 1.00e+00 | 0.496 | 1 | 11 | 399 |
GO:0006366 | transcription from RNA polymerase II promoter | 5.35e-01 | 1.00e+00 | 0.405 | 1 | 12 | 425 |
GO:0007596 | blood coagulation | 5.67e-01 | 1.00e+00 | 0.278 | 1 | 14 | 464 |
GO:0008270 | zinc ion binding | 5.74e-01 | 1.00e+00 | 0.077 | 2 | 12 | 1067 |
GO:0055114 | oxidation-reduction process | 5.80e-01 | 1.00e+00 | 0.227 | 1 | 11 | 481 |
GO:0045893 | positive regulation of transcription, DNA-templated | 5.85e-01 | 1.00e+00 | 0.209 | 1 | 17 | 487 |
GO:0044267 | cellular protein metabolic process | 5.91e-01 | 1.00e+00 | 0.185 | 1 | 24 | 495 |
GO:0042803 | protein homodimerization activity | 6.73e-01 | 1.00e+00 | -0.133 | 1 | 11 | 617 |
GO:0005789 | endoplasmic reticulum membrane | 6.85e-01 | 1.00e+00 | -0.176 | 1 | 10 | 636 |
GO:0045944 | positive regulation of transcription from RNA polymerase II promoter | 7.72e-01 | 1.00e+00 | -0.527 | 1 | 19 | 811 |
GO:0006351 | transcription, DNA-templated | 7.87e-01 | 1.00e+00 | -0.494 | 2 | 25 | 1585 |
GO:0007165 | signal transduction | 8.25e-01 | 1.00e+00 | -0.755 | 1 | 17 | 950 |
GO:0005615 | extracellular space | 8.43e-01 | 1.00e+00 | -0.844 | 1 | 17 | 1010 |
GO:0006355 | regulation of transcription, DNA-templated | 8.69e-01 | 1.00e+00 | -0.972 | 1 | 17 | 1104 |
GO:0003677 | DNA binding | 9.19e-01 | 1.00e+00 | -1.263 | 1 | 26 | 1351 |