meta-int-snw-5690

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-11277 wolf-screen-ratio-mammosphere-adherent 0.882 1.09e-07 9.11e-04 1.96e-03 10 9
int-snw-5690 wolf-screen-ratio-mammosphere-adherent 1.026 3.11e-19 2.88e-04 7.94e-03 7 7
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-317781 wolf-screen-ratio-mammosphere-adherent 0.823 1.13e-06 3.23e-03 6.07e-03 9 9
reg-snw-10213 wolf-screen-ratio-mammosphere-adherent 0.815 1.49e-06 3.74e-03 6.93e-03 7 6
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-5690 subnetwork

Genes (29)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMB1 5689 610.6880.901113Yes-
PSMA3 5684 900.5330.815238Yes-
PSMA2 5683 1121.0931.106108Yes-
RBX1 9978 1151.1850.934148Yes-
POLR2F 5435 620.8910.95626Yes-
PSMB7 5695 1180.9820.93490Yes-
HNRNPC 3183 1081.8120.973181Yes-
PSMA1 5682 1000.9960.878152Yes-
VARS 7407 860.5491.002204Yes-
TREX1 11277 51-0.0510.88291Yes-
DDX51 317781 530.0590.823210Yes-
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
RPA1 6117 510.4250.86574--
CAD 790 910.8070.973400--
EIF6 3692 670.7000.876316Yes-
PSMD1 5707 860.8360.830118Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD3 5709 1000.9861.106201Yes-
EFTUD2 9343 930.8830.956108Yes-
PSMD14 10213 440.2990.81532--
PSMB2 5690 1160.8770.956169Yes-
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
ACTB 60 1341.1531.151610Yes-
RAN 5901 890.6320.899258Yes-
RUVBL2 10856 950.6930.956532Yes-
PRMT3 10196 490.4310.81526--
MTHFD1 4522 490.1940.81526Yes-

Interactions (137)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA1 5682 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, BIND_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, IntAct, IntAct_Mouse, IntAct_Yeast, Yu_GoldStd
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RPA1 6117 pd < reg.ITFP.txt: no annot
MTHFD1 4522 PSMA3 5684 pp -- int.I2D: BioGrid
PSMB2 5690 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB3 5691 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
CAD 790 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMB1 5689 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RAN 5901 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMB1 5689 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastHigh, IntAct, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMB3 5691 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
RPA1 6117 TREX1 11277 pp -- int.I2D: BCI;
int.HPRD: in vitro
PSMA3 5684 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD14 10213 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB1 5689 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB1 5689 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, MINT, YeastHigh, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast;
int.Mint: MI:0915(physical association)
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
TREX1 11277 DDX51 317781 pd <> reg.ITFP.txt: no annot
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
PSMA1 5682 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastMedium
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
PSMD1 5707 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMD11 5717 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct, INTEROLOG
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
CAD 790 DDX51 317781 pp -- int.I2D: IntAct_Yeast
VARS 7407 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMB1 5689 PSMB7 5695 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, HPRD, MINT, YeastLow, IntAct, Krogan_Core, MINT_Yeast, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB7 5695 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RAN 5901 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, NON_CORE
RAN 5901 VARS 7407 pd < reg.ITFP.txt: no annot
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RAN 5901 pp -- int.I2D: IntAct_Yeast
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
VARS 7407 DDX51 317781 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMB7 5695 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMB1 5689 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
MTHFD1 4522 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 DDX51 317781 pd < reg.ITFP.txt: no annot
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB1 5689 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, IntAct_Yeast, YeastHigh
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
PSMB1 5689 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMB1 5689 TREX1 11277 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB1 5689 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA2 5683 PSMB1 5689 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, BCI, BioGrid, IntAct, YeastHigh
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD14 10213 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
PSMD3 5709 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
EIF6 3692 DDX51 317781 pd < reg.ITFP.txt: no annot
EIF6 3692 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RAN 5901 TREX1 11277 pd < reg.ITFP.txt: no annot
RUVBL2 10856 TREX1 11277 pd <> reg.ITFP.txt: no annot
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
EIF6 3692 RUVBL1 8607 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct

Related GO terms (340)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0006521regulation of cellular amino acid metabolic process2.27e-213.71e-176.952112150
GO:0000502proteasome complex1.37e-202.24e-166.738112258
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.36e-208.76e-166.574112465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest5.36e-208.76e-166.574112265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.29e-192.11e-156.467112470
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.12e-193.45e-156.406112373
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.48e-194.05e-156.386112474
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I3.96e-196.46e-156.329112377
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process5.34e-198.72e-156.292112579
GO:0002474antigen processing and presentation of peptide antigen via MHC class I4.02e-186.56e-146.041112394
GO:0000082G1/S transition of mitotic cell cycle1.05e-171.72e-135.4931233150
GO:0005654nucleoplasm1.62e-172.65e-133.36220831095
GO:0000209protein polyubiquitination4.47e-177.30e-135.7381121116
GO:0005839proteasome core complex8.02e-161.31e-117.77471118
GO:0042981regulation of apoptotic process8.82e-161.44e-115.3571126151
GO:0004298threonine-type endopeptidase activity1.95e-153.18e-117.62271120
GO:0010467gene expression2.20e-153.59e-113.7511658669
GO:0034641cellular nitrogen compound metabolic process5.21e-158.51e-115.1281125177
GO:0000278mitotic cell cycle4.23e-146.91e-104.2001352398
GO:0016071mRNA metabolic process6.75e-141.10e-094.7951134223
GO:0016032viral process7.84e-141.28e-093.8671455540
GO:0016070RNA metabolic process2.08e-133.39e-094.6481134247
GO:0005829cytosol9.51e-131.55e-082.273221252562
GO:0043066negative regulation of apoptotic process9.09e-111.48e-063.8381130433
GO:0070062extracellular vesicular exosome1.47e-092.39e-052.08719982516
GO:0006915apoptotic process1.70e-092.78e-053.4391134571
GO:0044281small molecule metabolic process9.12e-091.49e-042.60514571295
GO:0022624proteasome accessory complex1.88e-083.07e-047.0494917
GO:0019773proteasome core complex, alpha-subunit complex2.81e-074.58e-037.721358
GO:0005838proteasome regulatory particle1.10e-061.79e-027.1363712
GO:0035267NuA4 histone acetyltransferase complex1.81e-062.96e-026.9143414
GO:0005730nucleolus1.99e-063.24e-022.11913701684
GO:0005634nucleus2.32e-063.79e-021.292211314828
GO:0016020membrane2.99e-064.89e-022.06713801746
GO:0006310DNA recombination5.70e-069.31e-025.0704467
GO:0006281DNA repair5.88e-069.60e-023.677622264
GO:0000812Swr1 complex8.48e-051.00e+007.136238
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.18e-041.00e+004.9673554
GO:0043968histone H2A acetylation1.99e-041.00e+006.5512312
GO:0030234enzyme regulator activity2.35e-041.00e+006.4362313
GO:0031011Ino80 complex2.74e-041.00e+006.3292314
GO:0042176regulation of protein catabolic process3.60e-041.00e+006.1362316
GO:0006259DNA metabolic process5.12e-041.00e+005.8892319
GO:0003678DNA helicase activity5.12e-041.00e+005.8892319
GO:0006298mismatch repair5.68e-041.00e+005.8152620
GO:0016363nuclear matrix5.70e-041.00e+004.19831192
GO:0005515protein binding5.88e-041.00e+000.877201726127
GO:0043044ATP-dependent chromatin remodeling7.54e-041.00e+005.6132423
GO:0071339MLL1 complex1.04e-031.00e+005.3822327
GO:0030529ribonucleoprotein complex1.06e-031.00e+003.88938114
GO:0043967histone H4 acetylation1.12e-031.00e+005.3292328
GO:0031492nucleosomal DNA binding1.12e-031.00e+005.3292428
GO:0006325chromatin organization1.32e-031.00e+003.77934123
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity1.78e-031.00e+009.136111
GO:0070335aspartate binding1.78e-031.00e+009.136111
GO:0008541proteasome regulatory particle, lid subcomplex1.78e-031.00e+009.136111
GO:0032558adenyl deoxyribonucleotide binding1.78e-031.00e+009.136111
GO:0004151dihydroorotase activity1.78e-031.00e+009.136111
GO:0000054ribosomal subunit export from nucleus1.78e-031.00e+009.136111
GO:0004070aspartate carbamoyltransferase activity1.78e-031.00e+009.136111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity1.78e-031.00e+009.136111
GO:0032508DNA duplex unwinding2.51e-031.00e+004.7442442
GO:0006283transcription-coupled nucleotide-excision repair3.01e-031.00e+004.6132846
GO:0000398mRNA splicing, via spliceosome3.06e-031.00e+003.355312165
GO:0004832valine-tRNA ligase activity3.55e-031.00e+008.136112
GO:0006438valyl-tRNA aminoacylation3.55e-031.00e+008.136112
GO:0000105histidine biosynthetic process3.55e-031.00e+008.136112
GO:00082963'-5'-exodeoxyribonuclease activity3.55e-031.00e+008.136112
GO:0070409carbamoyl phosphate biosynthetic process3.55e-031.00e+008.136112
GO:0040008regulation of growth3.68e-031.00e+004.4642351
GO:0003684damaged DNA binding3.68e-031.00e+004.46421151
GO:0000724double-strand break repair via homologous recombination4.58e-031.00e+004.3042657
GO:0032481positive regulation of type I interferon production5.23e-031.00e+004.2062661
GO:0071899negative regulation of estrogen receptor binding5.32e-031.00e+007.551113
GO:0071733transcriptional activation by promoter-enhancer looping5.32e-031.00e+007.551113
GO:0000056ribosomal small subunit export from nucleus5.32e-031.00e+007.551113
GO:0044205'de novo' UMP biosynthetic process5.32e-031.00e+007.551113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process5.32e-031.00e+007.551113
GO:0003924GTPase activity5.46e-031.00e+003.05639203
GO:0006289nucleotide-excision repair6.64e-031.00e+004.02821269
GO:0003697single-stranded DNA binding6.64e-031.00e+004.0282969
GO:0006184GTP catabolic process6.82e-031.00e+002.94039220
GO:0000212meiotic spindle organization7.09e-031.00e+007.136114
GO:0019788NEDD8 ligase activity7.09e-031.00e+007.136114
GO:0016274protein-arginine N-methyltransferase activity7.09e-031.00e+007.136114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity7.09e-031.00e+007.136114
GO:0004329formate-tetrahydrofolate ligase activity7.09e-031.00e+007.136114
GO:0043141ATP-dependent 5'-3' DNA helicase activity7.09e-031.00e+007.136114
GO:0034969histone arginine methylation7.09e-031.00e+007.136114
GO:0006543glutamine catabolic process7.09e-031.00e+007.136114
GO:0009396folic acid-containing compound biosynthetic process7.09e-031.00e+007.136114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity7.09e-031.00e+007.136114
GO:0031467Cul7-RING ubiquitin ligase complex7.09e-031.00e+007.136114
GO:0000055ribosomal large subunit export from nucleus7.09e-031.00e+007.136114
GO:0008853exodeoxyribonuclease III activity7.09e-031.00e+007.136114
GO:0008380RNA splicing7.89e-031.00e+002.863313232
GO:0005524ATP binding8.18e-031.00e+001.5417461354
GO:0071013catalytic step 2 spliceosome8.63e-031.00e+003.8332779
GO:0051414response to cortisol8.85e-031.00e+006.815115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex8.85e-031.00e+006.815125
GO:0042256mature ribosome assembly8.85e-031.00e+006.815115
GO:0009086methionine biosynthetic process8.85e-031.00e+006.815115
GO:0032407MutSalpha complex binding8.85e-031.00e+006.815115
GO:0008622epsilon DNA polymerase complex8.85e-031.00e+006.815115
GO:0031461cullin-RING ubiquitin ligase complex8.85e-031.00e+006.815115
GO:0071169establishment of protein localization to chromatin8.85e-031.00e+006.815115
GO:0043248proteasome assembly8.85e-031.00e+006.815115
GO:0030891VCB complex8.85e-031.00e+006.815125
GO:0005827polar microtubule8.85e-031.00e+006.815115
GO:0000730DNA recombinase assembly8.85e-031.00e+006.815135
GO:0005638lamin filament8.85e-031.00e+006.815115
GO:0061133endopeptidase activator activity8.85e-031.00e+006.815115
GO:0005681spliceosomal complex9.49e-031.00e+003.7612383
GO:0043023ribosomal large subunit binding1.06e-021.00e+006.551126
GO:0031466Cul5-RING ubiquitin ligase complex1.06e-021.00e+006.551116
GO:0030957Tat protein binding1.06e-021.00e+006.551146
GO:0046134pyrimidine nucleoside biosynthetic process1.06e-021.00e+006.551116
GO:0032405MutLalpha complex binding1.06e-021.00e+006.551126
GO:0008469histone-arginine N-methyltransferase activity1.06e-021.00e+006.551116
GO:0005200structural constituent of cytoskeleton1.18e-021.00e+003.5972793
GO:0010950positive regulation of endopeptidase activity1.24e-021.00e+006.329117
GO:0002161aminoacyl-tRNA editing activity1.24e-021.00e+006.329127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.24e-021.00e+006.329117
GO:0031462Cul2-RING ubiquitin ligase complex1.24e-021.00e+006.329127
GO:0035999tetrahydrofolate interconversion1.24e-021.00e+006.329117
GO:0072341modified amino acid binding1.24e-021.00e+006.329117
GO:0000930gamma-tubulin complex1.24e-021.00e+006.329117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.24e-021.00e+006.329117
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.41e-021.00e+006.136128
GO:0001055RNA polymerase II activity1.41e-021.00e+006.136138
GO:0070688MLL5-L complex1.41e-021.00e+006.136118
GO:0045116protein neddylation1.41e-021.00e+006.136128
GO:0000800lateral element1.41e-021.00e+006.136118
GO:0006164purine nucleotide biosynthetic process1.41e-021.00e+006.136128
GO:0043234protein complex1.58e-021.00e+002.493317300
GO:0014075response to amine1.59e-021.00e+005.967119
GO:0006228UTP biosynthetic process1.59e-021.00e+005.967119
GO:0031000response to caffeine1.59e-021.00e+005.967129
GO:0070628proteasome binding1.76e-021.00e+005.8151110
GO:0046655folic acid metabolic process1.76e-021.00e+005.8151110
GO:0006450regulation of translational fidelity1.76e-021.00e+005.8151210
GO:0001054RNA polymerase I activity1.94e-021.00e+005.6771311
GO:0045120pronucleus1.94e-021.00e+005.6771111
GO:0035458cellular response to interferon-beta1.94e-021.00e+005.6771211
GO:0005525GTP binding2.00e-021.00e+002.364311328
GO:0006260DNA replication2.06e-021.00e+003.171212125
GO:0061136regulation of proteasomal protein catabolic process2.11e-021.00e+005.5511112
GO:00709353'-UTR-mediated mRNA stabilization2.11e-021.00e+005.5511212
GO:0005736DNA-directed RNA polymerase I complex2.11e-021.00e+005.5511312
GO:0006511ubiquitin-dependent protein catabolic process2.13e-021.00e+003.14825127
GO:0042273ribosomal large subunit biogenesis2.29e-021.00e+005.4361413
GO:0032479regulation of type I interferon production2.29e-021.00e+005.4361213
GO:0005662DNA replication factor A complex2.29e-021.00e+005.4361313
GO:0000738DNA catabolic process, exonucleolytic2.29e-021.00e+005.4361213
GO:0008266poly(U) RNA binding2.29e-021.00e+005.4361113
GO:0000790nuclear chromatin2.32e-021.00e+003.08127133
GO:0007020microtubule nucleation2.46e-021.00e+005.3291114
GO:0035066positive regulation of histone acetylation2.63e-021.00e+005.2301115
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex2.63e-021.00e+005.2301115
GO:0006261DNA-dependent DNA replication2.63e-021.00e+005.2301215
GO:0016887ATPase activity2.69e-021.00e+002.96727144
GO:0005665DNA-directed RNA polymerase II, core complex2.81e-021.00e+005.1361416
GO:0050998nitric-oxide synthase binding2.81e-021.00e+005.1361116
GO:0001673male germ cell nucleus2.81e-021.00e+005.1361116
GO:0001056RNA polymerase III activity2.81e-021.00e+005.1361316
GO:00084083'-5' exonuclease activity2.81e-021.00e+005.1361216
GO:0006457protein folding2.86e-021.00e+002.91728149
GO:0010243response to organonitrogen compound2.98e-021.00e+005.0491217
GO:0005666DNA-directed RNA polymerase III complex2.98e-021.00e+005.0491317
GO:0075733intracellular transport of virus2.98e-021.00e+005.0491217
GO:0007126meiotic nuclear division2.98e-021.00e+005.0491117
GO:0070536protein K63-linked deubiquitination3.15e-021.00e+004.9671118
GO:0006386termination of RNA polymerase III transcription3.15e-021.00e+004.9671318
GO:0071392cellular response to estradiol stimulus3.15e-021.00e+004.9671118
GO:0006541glutamine metabolic process3.15e-021.00e+004.9671118
GO:0031122cytoplasmic microtubule organization3.15e-021.00e+004.9671218
GO:0006385transcription elongation from RNA polymerase III promoter3.15e-021.00e+004.9671318
GO:0006303double-strand break repair via nonhomologous end joining3.15e-021.00e+004.9671318
GO:0005737cytoplasm3.23e-021.00e+000.76412983976
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process3.32e-021.00e+004.8891119
GO:0048863stem cell differentiation3.32e-021.00e+004.8891119
GO:0048873homeostasis of number of cells within a tissue3.50e-021.00e+004.8151120
GO:0005719nuclear euchromatin3.50e-021.00e+004.8151220
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding3.57e-021.00e+002.74425168
GO:0000718nucleotide-excision repair, DNA damage removal3.67e-021.00e+004.7441521
GO:0071364cellular response to epidermal growth factor stimulus3.67e-021.00e+004.7441121
GO:0006297nucleotide-excision repair, DNA gap filling3.84e-021.00e+004.6771522
GO:0033574response to testosterone3.84e-021.00e+004.6771222
GO:0032201telomere maintenance via semi-conservative replication3.84e-021.00e+004.6771722
GO:0030863cortical cytoskeleton3.84e-021.00e+004.6771122
GO:0036464cytoplasmic ribonucleoprotein granule3.84e-021.00e+004.6771422
GO:0007052mitotic spindle organization3.84e-021.00e+004.6771222
GO:0031463Cul3-RING ubiquitin ligase complex4.01e-021.00e+004.6131223
GO:0006513protein monoubiquitination4.01e-021.00e+004.6131123
GO:0015629actin cytoskeleton4.16e-021.00e+002.62125183
GO:0000794condensed nuclear chromosome4.18e-021.00e+004.5511224
GO:0006206pyrimidine nucleobase metabolic process4.18e-021.00e+004.5511224
GO:0006611protein export from nucleus4.35e-021.00e+004.4931425
GO:0005844polysome4.35e-021.00e+004.4931425
GO:0017144drug metabolic process4.35e-021.00e+004.4931125
GO:0000722telomere maintenance via recombination4.52e-021.00e+004.4361726
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia4.52e-021.00e+004.4361226
GO:0006730one-carbon metabolic process4.52e-021.00e+004.4361126
GO:0004003ATP-dependent DNA helicase activity4.69e-021.00e+004.3821327
GO:0034080CENP-A containing nucleosome assembly4.69e-021.00e+004.3821227
GO:0043022ribosome binding4.86e-021.00e+004.3291328
GO:0019894kinesin binding4.86e-021.00e+004.3291128
GO:0019005SCF ubiquitin ligase complex5.03e-021.00e+004.2781129
GO:0003730mRNA 3'-UTR binding5.03e-021.00e+004.2781229
GO:0003887DNA-directed DNA polymerase activity5.03e-021.00e+004.2781329
GO:0071897DNA biosynthetic process5.03e-021.00e+004.2781229
GO:00063707-methylguanosine mRNA capping5.20e-021.00e+004.2301430
GO:0006360transcription from RNA polymerase I promoter5.20e-021.00e+004.2301430
GO:0006271DNA strand elongation involved in DNA replication5.37e-021.00e+004.1821931
GO:0031397negative regulation of protein ubiquitination5.54e-021.00e+004.1361132
GO:0034644cellular response to UV5.54e-021.00e+004.1361532
GO:0042802identical protein binding5.55e-021.00e+001.782318491
GO:0034332adherens junction organization6.21e-021.00e+003.9671136
GO:0004221ubiquitin thiolesterase activity6.21e-021.00e+003.9671236
GO:0001895retina homeostasis6.21e-021.00e+003.9671136
GO:0007067mitotic nuclear division6.31e-021.00e+002.285213231
GO:0051084'de novo' posttranslational protein folding6.38e-021.00e+003.9271437
GO:0018107peptidyl-threonine phosphorylation6.38e-021.00e+003.9271137
GO:0070527platelet aggregation6.54e-021.00e+003.8891238
GO:0050681androgen receptor binding6.54e-021.00e+003.8891438
GO:0006383transcription from RNA polymerase III promoter6.71e-021.00e+003.8511339
GO:0008026ATP-dependent helicase activity6.71e-021.00e+003.8511339
GO:0031490chromatin DNA binding6.71e-021.00e+003.8511239
GO:0006284base-excision repair6.71e-021.00e+003.8511739
GO:0032092positive regulation of protein binding6.71e-021.00e+003.8511339
GO:0007595lactation6.71e-021.00e+003.8511239
GO:0043195terminal bouton7.04e-021.00e+003.7791141
GO:0030521androgen receptor signaling pathway7.04e-021.00e+003.7791241
GO:0006418tRNA aminoacylation for protein translation7.21e-021.00e+003.7441542
GO:0014070response to organic cyclic compound7.37e-021.00e+003.7101343
GO:0007286spermatid development7.54e-021.00e+003.6771144
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding7.54e-021.00e+003.6771244
GO:0050434positive regulation of viral transcription7.54e-021.00e+003.6771544
GO:0015030Cajal body7.70e-021.00e+003.6451245
GO:0043966histone H3 acetylation7.70e-021.00e+003.6451245
GO:0021762substantia nigra development7.87e-021.00e+003.6131146
GO:0019003GDP binding8.19e-021.00e+003.5511248
GO:0003743translation initiation factor activity8.36e-021.00e+003.5221449
GO:0031100organ regeneration8.52e-021.00e+003.4931450
GO:0035690cellular response to drug8.52e-021.00e+003.4931250
GO:0008168methyltransferase activity8.85e-021.00e+003.4361152
GO:0090305nucleic acid phosphodiester bond hydrolysis9.17e-021.00e+003.3821254
GO:0000226microtubule cytoskeleton organization9.33e-021.00e+003.3551355
GO:0045087innate immune response9.48e-021.00e+001.455320616
GO:0000932cytoplasmic mRNA processing body9.49e-021.00e+003.3291356
GO:0030097hemopoiesis9.82e-021.00e+003.2781358
GO:0008237metallopeptidase activity9.82e-021.00e+003.2781158
GO:0005840ribosome9.98e-021.00e+003.2541259
GO:0045216cell-cell junction organization9.98e-021.00e+003.2541259
GO:0000723telomere maintenance9.98e-021.00e+003.2541859
GO:0005643nuclear pore9.98e-021.00e+003.2541459
GO:0006200ATP catabolic process1.01e-011.00e+001.893214303
GO:0006302double-strand break repair1.05e-011.00e+003.1821862
GO:0042995cell projection1.06e-011.00e+003.1591663
GO:0006368transcription elongation from RNA polymerase II promoter1.13e-011.00e+003.0701667
GO:0006338chromatin remodeling1.14e-011.00e+003.0491468
GO:0003682chromatin binding1.18e-011.00e+001.753212334
GO:0034329cell junction assembly1.19e-011.00e+002.9871171
GO:0005813centrosome1.21e-011.00e+001.731212339
GO:0044822poly(A) RNA binding1.21e-011.00e+001.0624501078
GO:0000785chromatin1.22e-011.00e+002.9471573
GO:0055086nucleobase-containing small molecule metabolic process1.22e-011.00e+002.9471573
GO:0006767water-soluble vitamin metabolic process1.25e-011.00e+002.9081375
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.27e-011.00e+002.8891376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.28e-011.00e+002.8701577
GO:0006766vitamin metabolic process1.30e-011.00e+002.8511378
GO:0006334nucleosome assembly1.31e-011.00e+002.8331479
GO:0003723RNA binding1.31e-011.00e+001.665219355
GO:0007565female pregnancy1.33e-011.00e+002.8151280
GO:0001889liver development1.36e-011.00e+002.7791382
GO:0003690double-stranded DNA binding1.50e-011.00e+002.6291491
GO:0016605PML body1.51e-011.00e+002.6131592
GO:0042470melanosome1.51e-011.00e+002.61311092
GO:0006928cellular component movement1.51e-011.00e+002.6131792
GO:0051082unfolded protein binding1.56e-011.00e+002.5671695
GO:0001649osteoblast differentiation1.56e-011.00e+002.5671695
GO:0006364rRNA processing1.57e-011.00e+002.5511596
GO:0071456cellular response to hypoxia1.60e-011.00e+002.5221498
GO:0014069postsynaptic density1.72e-011.00e+002.40911106
GO:0005815microtubule organizing center1.78e-011.00e+002.35514110
GO:0015630microtubule cytoskeleton1.81e-011.00e+002.32915112
GO:0019058viral life cycle1.86e-011.00e+002.291110115
GO:0005635nuclear envelope1.87e-011.00e+002.27816116
GO:0072562blood microparticle1.87e-011.00e+002.27814116
GO:0007219Notch signaling pathway2.00e-011.00e+002.17114125
GO:0006413translational initiation2.09e-011.00e+002.103112131
GO:0009615response to virus2.10e-011.00e+002.09216132
GO:0000086G2/M transition of mitotic cell cycle2.17e-011.00e+002.03817137
GO:0007507heart development2.23e-011.00e+001.99715141
GO:0061024membrane organization2.30e-011.00e+001.94715146
GO:0046777protein autophosphorylation2.46e-011.00e+001.83313158
GO:0046872metal ion binding2.60e-011.00e+000.6204241465
GO:0006397mRNA processing2.61e-011.00e+001.73613169
GO:0030424axon2.65e-011.00e+001.71013172
GO:0016607nuclear speck2.69e-011.00e+001.68514175
GO:0004672protein kinase activity2.73e-011.00e+001.66112178
GO:0031625ubiquitin protein ligase binding2.75e-011.00e+001.645113180
GO:0019904protein domain specific binding2.77e-011.00e+001.63716181
GO:0006367transcription initiation from RNA polymerase II promoter2.80e-011.00e+001.61318184
GO:0032403protein complex binding2.82e-011.00e+001.60517185
GO:0005739mitochondrion2.84e-011.00e+000.6913241046
GO:0001701in utero embryonic development3.13e-011.00e+001.42216210
GO:0005794Golgi apparatus3.22e-011.00e+000.792214650
GO:0005622intracellular3.33e-011.00e+001.31615226
GO:0003713transcription coactivator activity3.48e-011.00e+001.236110239
GO:0043025neuronal cell body3.66e-011.00e+001.14814254
GO:0004842ubiquitin-protein transferase activity3.68e-011.00e+001.13614256
GO:0000166nucleotide binding3.86e-011.00e+001.04916272
GO:0006357regulation of transcription from RNA polymerase II promoter3.89e-011.00e+001.03316275
GO:0007283spermatogenesis3.90e-011.00e+001.02816276
GO:0019899enzyme binding4.04e-011.00e+000.967111288
GO:0007264small GTPase mediated signal transduction4.06e-011.00e+000.95713290
GO:0016567protein ubiquitination4.15e-011.00e+000.91215299
GO:0005856cytoskeleton4.28e-011.00e+000.85618311
GO:0019901protein kinase binding4.37e-011.00e+000.815121320
GO:0007411axon guidance4.44e-011.00e+000.78319327
GO:0043231intracellular membrane-bounded organelle4.49e-011.00e+000.76118332
GO:0043565sequence-specific DNA binding4.81e-011.00e+000.62514365
GO:0005925focal adhesion4.86e-011.00e+000.605118370
GO:0008284positive regulation of cell proliferation5.06e-011.00e+000.52218392
GO:0046982protein heterodimerization activity5.12e-011.00e+000.496111399
GO:0006366transcription from RNA polymerase II promoter5.35e-011.00e+000.405112425
GO:0007596blood coagulation5.67e-011.00e+000.278114464
GO:0008270zinc ion binding5.74e-011.00e+000.0772121067
GO:0055114oxidation-reduction process5.80e-011.00e+000.227111481
GO:0045893positive regulation of transcription, DNA-templated5.85e-011.00e+000.209117487
GO:0044267cellular protein metabolic process5.91e-011.00e+000.185124495
GO:0042803protein homodimerization activity6.73e-011.00e+00-0.133111617
GO:0005789endoplasmic reticulum membrane6.85e-011.00e+00-0.176110636
GO:0045944positive regulation of transcription from RNA polymerase II promoter7.72e-011.00e+00-0.527119811
GO:0006351transcription, DNA-templated7.87e-011.00e+00-0.4942251585
GO:0007165signal transduction8.25e-011.00e+00-0.755117950
GO:0005615extracellular space8.43e-011.00e+00-0.8441171010
GO:0006355regulation of transcription, DNA-templated8.69e-011.00e+00-0.9721171104
GO:0003677DNA binding9.19e-011.00e+00-1.2631261351