int-snw-5690

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	1.026	3.11e-19	2.88e-04	7.94e-03

wolf-screen-ratio-mammosphere-adherent-int-snw-5690 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ PSMB2 ]	5690	18	0.877	1.026	117	Yes	-
PSMA1	5682	61	0.996	1.052	123	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
PSMA2	5683	60	1.093	1.106	89	Yes	-
PSMD3	5709	57	0.986	1.106	146	Yes	-
PSMB7	5695	48	0.982	1.052	57	Yes	-

Interactions (20)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB7	5695	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMB2	5690	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
PSMA1	5682	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMA2	5683	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMB2	5690	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
ACTB	60	PSMA1	5682	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMB2	5690	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
PSMA1	5682	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMA1	5682	PSMA2	5683	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid

Related GO terms (87)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006521	regulation of cellular amino acid metabolic process	8.88e-15	1.28e-10	7.950	6	17	50
GO:0000502	proteasome complex	2.26e-14	3.26e-10	7.736	6	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.19e-14	6.04e-10	7.594	6	19	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.61e-14	6.65e-10	7.571	6	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.32e-14	1.06e-09	7.464	6	22	70
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	8.72e-14	1.26e-09	7.424	6	20	72
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.03e-13	1.49e-09	7.384	6	22	74
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.12e-13	1.62e-09	7.365	6	20	75
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.55e-13	2.24e-09	7.290	6	23	79
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	3.98e-13	5.73e-09	7.070	6	21	92
GO:0000209	protein polyubiquitination	1.65e-12	2.38e-08	6.736	6	20	116
GO:0000082	G1/S transition of mitotic cell cycle	7.63e-12	1.10e-07	6.375	6	32	149
GO:0042981	regulation of apoptotic process	7.94e-12	1.15e-07	6.365	6	24	150
GO:0034641	cellular nitrogen compound metabolic process	1.76e-11	2.54e-07	6.176	6	20	171
GO:0005839	proteasome core complex	5.93e-11	8.55e-07	8.839	4	8	18
GO:0004298	threonine-type endopeptidase activity	7.51e-11	1.08e-06	8.761	4	8	19
GO:0016071	mRNA metabolic process	8.83e-11	1.27e-06	5.793	6	31	223
GO:0016070	RNA metabolic process	1.64e-10	2.36e-06	5.645	6	32	247
GO:0000278	mitotic cell cycle	2.62e-09	3.77e-05	4.983	6	48	391
GO:0043066	negative regulation of apoptotic process	4.26e-09	6.14e-05	4.866	6	31	424
GO:0005654	nucleoplasm	1.31e-08	1.89e-04	3.737	7	76	1082
GO:0016032	viral process	1.70e-08	2.45e-04	4.533	6	55	534
GO:0006915	apoptotic process	2.14e-08	3.09e-04	4.477	6	33	555
GO:0010467	gene expression	6.55e-08	9.45e-04	4.208	6	59	669
GO:0044281	small molecule metabolic process	2.25e-06	3.25e-02	3.352	6	58	1211
GO:0070062	extracellular vesicular exosome	3.51e-06	5.06e-02	2.587	7	104	2400
GO:0005829	cytosol	4.62e-06	6.66e-02	2.531	7	132	2496
GO:0019773	proteasome core complex, alpha-subunit complex	5.65e-06	8.14e-02	9.009	2	4	8
GO:0005838	proteasome regulatory particle	1.33e-05	1.92e-01	8.424	2	7	12
GO:0022624	proteasome accessory complex	2.74e-05	3.95e-01	7.921	2	8	17
GO:0043248	proteasome assembly	2.42e-03	1.00e+00	8.687	1	1	5
GO:0030957	Tat protein binding	2.91e-03	1.00e+00	8.424	1	3	6
GO:0070688	MLL5-L complex	3.88e-03	1.00e+00	8.009	1	1	8
GO:0005730	nucleolus	4.40e-03	1.00e+00	2.328	4	69	1641
GO:0016020	membrane	4.81e-03	1.00e+00	2.294	4	90	1681
GO:0005634	nucleus	5.08e-03	1.00e+00	1.439	6	136	4559
GO:0030234	enzyme regulator activity	6.29e-03	1.00e+00	7.308	1	3	13
GO:0035267	NuA4 histone acetyltransferase complex	6.78e-03	1.00e+00	7.201	1	4	14
GO:0050998	nitric-oxide synthase binding	7.74e-03	1.00e+00	7.009	1	1	16
GO:0042176	regulation of protein catabolic process	7.74e-03	1.00e+00	7.009	1	3	16
GO:0010243	response to organonitrogen compound	8.22e-03	1.00e+00	6.921	1	3	17
GO:0048863	stem cell differentiation	9.19e-03	1.00e+00	6.761	1	1	19
GO:0030863	cortical cytoskeleton	1.06e-02	1.00e+00	6.549	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	1.06e-02	1.00e+00	6.549	1	4	22
GO:0043044	ATP-dependent chromatin remodeling	1.11e-02	1.00e+00	6.485	1	4	23
GO:0005844	polysome	1.11e-02	1.00e+00	6.485	1	4	23
GO:0031492	nucleosomal DNA binding	1.30e-02	1.00e+00	6.254	1	4	27
GO:0019894	kinesin binding	1.35e-02	1.00e+00	6.201	1	1	28
GO:0001895	retina homeostasis	1.64e-02	1.00e+00	5.921	1	1	34
GO:0034332	adherens junction organization	1.73e-02	1.00e+00	5.839	1	1	36
GO:0051084	'de novo' posttranslational protein folding	1.78e-02	1.00e+00	5.799	1	4	37
GO:0070527	platelet aggregation	1.83e-02	1.00e+00	5.761	1	2	38
GO:0014070	response to organic cyclic compound	2.07e-02	1.00e+00	5.582	1	4	43
GO:0021762	substantia nigra development	2.12e-02	1.00e+00	5.549	1	2	44
GO:0005515	protein binding	2.38e-02	1.00e+00	1.037	6	184	6024
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	2.54e-02	1.00e+00	5.281	1	5	53
GO:0045216	cell-cell junction organization	2.59e-02	1.00e+00	5.254	1	2	54
GO:0000932	cytoplasmic mRNA processing body	2.59e-02	1.00e+00	5.254	1	3	54
GO:0034329	cell junction assembly	3.25e-02	1.00e+00	4.921	1	1	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	3.54e-02	1.00e+00	4.799	1	6	74
GO:0005200	structural constituent of cytoskeleton	4.33e-02	1.00e+00	4.501	1	8	91
GO:0006928	cellular component movement	4.33e-02	1.00e+00	4.501	1	7	91
GO:0014069	postsynaptic density	4.99e-02	1.00e+00	4.294	1	3	105
GO:0015630	microtubule cytoskeleton	5.22e-02	1.00e+00	4.227	1	4	110
GO:0072562	blood microparticle	5.27e-02	1.00e+00	4.214	1	3	111
GO:0030529	ribonucleoprotein complex	5.31e-02	1.00e+00	4.201	1	8	112
GO:0006325	chromatin organization	5.59e-02	1.00e+00	4.126	1	5	118
GO:0006511	ubiquitin-dependent protein catabolic process	5.96e-02	1.00e+00	4.031	1	5	126
GO:0009615	response to virus	5.96e-02	1.00e+00	4.031	1	5	126
GO:0000790	nuclear chromatin	6.10e-02	1.00e+00	3.998	1	9	129
GO:0006457	protein folding	6.74e-02	1.00e+00	3.849	1	7	143
GO:0061024	membrane organization	6.83e-02	1.00e+00	3.829	1	7	145
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	7.74e-02	1.00e+00	3.642	1	7	165
GO:0030424	axon	7.79e-02	1.00e+00	3.634	1	4	166
GO:0005856	cytoskeleton	1.33e-01	1.00e+00	2.824	1	12	291
GO:0043234	protein complex	1.35e-01	1.00e+00	2.804	1	18	295
GO:0019901	protein kinase binding	1.44e-01	1.00e+00	2.700	1	21	317
GO:0007411	axon guidance	1.45e-01	1.00e+00	2.691	1	13	319
GO:0005813	centrosome	1.48e-01	1.00e+00	2.660	1	14	326
GO:0003723	RNA binding	1.55e-01	1.00e+00	2.591	1	20	342
GO:0005925	focal adhesion	1.65e-01	1.00e+00	2.493	1	19	366
GO:0007596	blood coagulation	2.01e-01	1.00e+00	2.179	1	18	455
GO:0044267	cellular protein metabolic process	2.09e-01	1.00e+00	2.120	1	29	474
GO:0045087	innate immune response	2.56e-01	1.00e+00	1.790	1	24	596
GO:0005615	extracellular space	3.82e-01	1.00e+00	1.106	1	17	957
GO:0005524	ATP binding	4.83e-01	1.00e+00	0.667	1	60	1298
GO:0005737	cytoplasm	5.83e-01	1.00e+00	0.130	2	110	3767

Wolf-ratios-Mammosphere-Adherent

int-snw-5690

Statistics

Genes (7)

Interactions (20)

Related GO terms (87)