meta-int-snw-4175

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-705 wolf-screen-ratio-mammosphere-adherent 0.854 3.41e-07 1.70e-03 3.42e-03 8 7
int-snw-4175 wolf-screen-ratio-mammosphere-adherent 0.962 1.47e-16 1.37e-03 2.60e-02 14 12
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
reg-snw-1841 wolf-screen-ratio-mammosphere-adherent 0.802 2.40e-06 4.81e-03 8.67e-03 9 8
reg-snw-1434 wolf-screen-ratio-mammosphere-adherent 0.865 2.23e-07 1.35e-03 2.78e-03 9 7
reg-snw-5925 wolf-screen-ratio-mammosphere-adherent 0.802 2.42e-06 4.82e-03 8.69e-03 8 5
reg-snw-10213 wolf-screen-ratio-mammosphere-adherent 0.815 1.49e-06 3.74e-03 6.93e-03 7 6
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-4175 subnetwork

Genes (39)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree Transcription factor wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
MCM6 4175 7-0.0890.96286TF--
PSMA3 5684 900.5330.815238-Yes-
PPCS 79717 31-0.5690.8022--Yes
POLR2F 5435 620.8910.95626-Yes-
CSE1L 1434 410.3040.86554-Yes-
VARS 7407 860.5491.002204TFYes-
ATP6V1B2 526 530.8811.076278---
TFRC 7037 310.7300.80217---
RPA2 6118 961.2501.15176-Yes-
CAD 790 910.8070.973400---
RB1 5925 31-0.1020.802351TF--
RSL24D1 51187 381.3001.02059-Yes-
CCNA2 890 540.5500.973246TFYes-
PSMD1 5707 860.8360.830118-Yes-
MCM5 4174 230.5780.830273TFYes-
EFTUD2 9343 930.8830.956108-Yes-
PSMD14 10213 440.2990.81532TF--
TUBG1 7283 980.9740.97391-Yes-
PRMT3 10196 490.4310.81526TF--
MTHFD1 4522 490.1940.81526-Yes-
DTYMK 1841 60.3970.80276---
RBX1 9978 1151.1850.934148TFYes-
PPIE 10450 310.5670.80241TF--
HNRNPC 3183 1081.8120.973181-Yes-
PSMB7 5695 1180.9820.93490-Yes-
PSMA1 5682 1000.9960.878152-Yes-
OGDH 4967 720.8470.802126-Yes-
RPSA 3921 1201.3271.151152-Yes-
RPA1 6117 510.4250.86574TF--
PGD 5226 891.2011.106152-Yes-
PES1 23481 170.5130.876254TFYes-
RUVBL1 8607 950.7200.973469TFYes-
PSMD13 5719 560.8480.801114TFYes-
PSMD3 5709 1000.9861.106201TFYes-
PSMB2 5690 1160.8770.956169-Yes-
ACTB 60 1341.1531.151610-Yes-
PFDN2 5202 120.8370.85477TFYes-
RUVBL2 10856 950.6930.956532TFYes-
BYSL 705 40.3000.85436---

Interactions (156)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMD13 5719 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Worm, IntAct_Yeast, MINT_Yeast, YeastHigh, BioGrid_Worm, BIND_Worm, CE_DATA, Krogan_Core, MINT_Worm
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
CAD 790 MCM5 4174 pd < reg.ITFP.txt: no annot
CAD 790 MCM5 4174 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastMedium, BioGrid, BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
CSE1L 1434 PSMD14 10213 pd < reg.ITFP.txt: no annot
MCM6 4175 PES1 23481 pp -- int.I2D: BioGrid_Yeast
RB1 5925 PPCS 79717 pd > reg.pazar.txt: no annot
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
CAD 790 RPA1 6117 pd < reg.ITFP.txt: no annot
MTHFD1 4522 PSMA3 5684 pp -- int.I2D: BioGrid
BYSL 705 PSMD1 5707 pp -- int.I2D: IntAct_Yeast
RB1 5925 RPA2 6118 pd > reg.pazar.txt: no annot
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
DTYMK 1841 RUVBL1 8607 pd < reg.ITFP.txt: no annot
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
DTYMK 1841 MCM6 4175 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMD1 5707 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
CCNA2 890 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
ATP6V1B2 526 OGDH 4967 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast
MCM6 4175 PSMA3 5684 pp -- int.I2D: BioGrid
CAD 790 RUVBL1 8607 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA3 5684 PSMD13 5719 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid
PSMA3 5684 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD14 10213 pp -- int.I2D: BioGrid, BioGrid_Yeast
MCM5 4174 EFTUD2 9343 pd > reg.ITFP.txt: no annot
PGD 5226 RB1 5925 pd < reg.pazar.txt: no annot
CCNA2 890 CSE1L 1434 pd > reg.ITFP.txt: no annot
OGDH 4967 RUVBL1 8607 pp -- int.I2D: YeastLow
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MCM6 4175 PSMD13 5719 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
RBX1 9978 PPIE 10450 pd <> reg.ITFP.txt: no annot
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
OGDH 4967 PES1 23481 pp -- int.I2D: YeastLow
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
RUVBL2 10856 PES1 23481 pd <> reg.ITFP.txt: no annot
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
MCM6 4175 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
PSMB2 5690 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastMedium
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
BYSL 705 MCM5 4174 pp -- int.I2D: YeastLow
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
DTYMK 1841 PES1 23481 pd < reg.ITFP.txt: no annot
CSE1L 1434 RPA1 6117 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
BYSL 705 RUVBL2 10856 pd < reg.ITFP.txt: no annot
BYSL 705 RUVBL1 8607 pd < reg.ITFP.txt: no annot
OGDH 4967 PSMD13 5719 pp -- int.I2D: YeastLow
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
MTHFD1 4522 PES1 23481 pp -- int.I2D: IntAct_Yeast, YeastLow
MCM5 4174 RPA1 6117 pd <> reg.ITFP.txt: no annot
MCM5 4174 RPA1 6117 pp -- int.I2D: BioGrid_Yeast
OGDH 4967 RB1 5925 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastMedium
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
OGDH 4967 PGD 5226 pp -- int.I2D: YeastLow
PSMD1 5707 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
ATP6V1B2 526 CSE1L 1434 pp -- int.I2D: IntAct_Yeast
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
CAD 790 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
ACTB 60 RB1 5925 pd < reg.ITFP.txt: no annot
VARS 7407 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
DTYMK 1841 MCM5 4174 pd < reg.ITFP.txt: no annot
CSE1L 1434 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
MCM5 4174 RPA2 6118 pp -- int.I2D: BioGrid, HPRD;
int.HPRD: yeast 2-hybrid
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CCNA2 890 RB1 5925 pp -- int.I2D: IntAct
OGDH 4967 PSMD14 10213 pp -- int.I2D: YeastLow
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
PSMD13 5719 RUVBL2 10856 pp -- int.I2D: YeastHigh
BYSL 705 PES1 23481 pd < reg.ITFP.txt: no annot
MCM6 4175 PSMA1 5682 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, BioGrid, HPRD, MINT, VidalHuman_core;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
CAD 790 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
BYSL 705 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
RUVBL1 8607 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
ATP6V1B2 526 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
DTYMK 1841 VARS 7407 pd < reg.ITFP.txt: no annot
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
MCM5 4174 PSMD13 5719 pp -- int.I2D: YeastLow
CSE1L 1434 MCM6 4175 pd < reg.ITFP.txt: no annot
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
MTHFD1 4522 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
OGDH 4967 PSMD3 5709 pp -- int.I2D: YeastLow
CAD 790 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
RPA1 6117 RPA2 6118 pp -- int.Intact: MI:0407(direct interaction), MI:0915(physical association);
int.I2D: HPRD, BCI, BioGrid, BIND, IntAct;
int.Transfac: -;
int.HPRD: in vitro, in vivo
PSMB7 5695 PSMD13 5719 pd < reg.ITFP.txt: no annot
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
PGD 5226 PES1 23481 pp -- int.I2D: YeastLow
PSMB7 5695 PPIE 10450 pd < reg.ITFP.txt: no annot
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ATP6V1B2 526 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
RB1 5925 TFRC 7037 pd > reg.ITFP.txt: no annot
CAD 790 PES1 23481 pd < reg.ITFP.txt: no annot
ACTB 60 CSE1L 1434 pp -- int.I2D: IntAct_Yeast
PSMD13 5719 PPIE 10450 pd <> reg.ITFP.txt: no annot
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
MCM6 4175 RPA1 6117 pd <> reg.ITFP.txt: no annot
MCM6 4175 RPA1 6117 pp -- int.I2D: BioGrid, BIND_Mouse
DTYMK 1841 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PFDN2 5202 PSMB7 5695 pd > reg.ITFP.txt: no annot
RPSA 3921 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMD14 10213 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD3 5709 PSMD13 5719 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT_Yeast, YeastHigh, BioGrid, BioGrid_Yeast, IntAct_Yeast, Krogan_Core
PSMD3 5709 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
RB1 5925 PPIE 10450 pd > reg.pazar.txt: no annot
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
MCM5 4174 MCM6 4175 pd <> reg.ITFP.txt: no annot
MCM5 4174 MCM6 4175 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, INTEROLOG, IntAct, MINT_Yeast, YeastLow
CCNA2 890 RPA1 6117 pp -- int.I2D: BioGrid
ACTB 60 MCM5 4174 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
ATP6V1B2 526 MCM5 4174 pp -- int.I2D: IntAct_Yeast
PES1 23481 RSL24D1 51187 pp -- int.I2D: BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MIPS, YeastLow
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
BYSL 705 PFDN2 5202 pd < reg.ITFP.txt: no annot
ATP6V1B2 526 MCM6 4175 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast

Related GO terms (477)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0000082G1/S transition of mitotic cell cycle1.30e-172.12e-135.1811333150
GO:0005654nucleoplasm2.13e-163.48e-123.07222831095
GO:0000278mitotic cell cycle7.28e-151.19e-103.9791552398
GO:0006521regulation of cellular amino acid metabolic process2.47e-134.03e-096.06582150
GO:0000502proteasome complex8.69e-131.42e-085.85182258
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.26e-123.69e-085.68782465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.26e-123.69e-085.68782265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle4.20e-126.85e-085.58082470
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent5.94e-129.70e-085.51982373
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.65e-121.09e-075.50082474
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I9.24e-121.51e-075.44282377
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.14e-111.86e-075.40582579
GO:0002474antigen processing and presentation of peptide antigen via MHC class I4.75e-117.75e-075.15482394
GO:0016032viral process1.82e-102.97e-063.3331355540
GO:0000209protein polyubiquitination2.61e-104.26e-064.851821116
GO:0034641cellular nitrogen compound metabolic process2.71e-104.42e-064.411925177
GO:0016071mRNA metabolic process2.10e-093.42e-054.078934223
GO:0042981regulation of apoptotic process2.15e-093.51e-054.471826151
GO:0010467gene expression2.49e-094.07e-053.0241358669
GO:0016070RNA metabolic process5.14e-098.38e-053.931934247
GO:0005829cytosol6.23e-091.02e-041.845221252562
GO:0005730nucleolus1.20e-081.95e-042.16118701684
GO:0070062extracellular vesicular exosome3.02e-084.93e-041.80421982516
GO:0022624proteasome accessory complex6.48e-081.06e-036.6224917
GO:0005839proteasome core complex8.31e-081.36e-036.53941118
GO:0004298threonine-type endopeptidase activity1.31e-072.14e-036.38741120
GO:0016020membrane1.48e-072.42e-032.02717801746
GO:0044281small molecule metabolic process8.32e-071.36e-022.17814571295
GO:0006271DNA strand elongation involved in DNA replication8.36e-071.36e-025.7554931
GO:0005838proteasome regulatory particle2.73e-064.46e-026.7093712
GO:0035267NuA4 histone acetyltransferase complex4.51e-067.36e-026.4873414
GO:0006915apoptotic process6.11e-069.97e-022.722934571
GO:0043066negative regulation of apoptotic process6.87e-061.12e-012.951830433
GO:0005634nucleus8.28e-061.35e-011.116251314828
GO:0003678DNA helicase activity1.19e-051.94e-016.0463319
GO:0006281DNA repair3.53e-055.76e-013.250622264
GO:0000730DNA recombinase assembly5.54e-059.04e-017.387235
GO:0032508DNA duplex unwinding1.36e-041.00e+004.9023442
GO:0000812Swr1 complex1.54e-041.00e+006.709238
GO:0019773proteasome core complex, alpha-subunit complex1.54e-041.00e+006.709258
GO:0006283transcription-coupled nucleotide-excision repair1.78e-041.00e+004.7703846
GO:0042555MCM complex1.98e-041.00e+006.539229
GO:0006260DNA replication2.19e-041.00e+003.743412125
GO:0003684damaged DNA binding2.43e-041.00e+004.62231151
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding2.88e-041.00e+004.5393554
GO:0000724double-strand break repair via homologous recombination3.38e-041.00e+004.4613657
GO:0043968histone H2A acetylation3.62e-041.00e+006.1242312
GO:0005662DNA replication factor A complex4.27e-041.00e+006.0092313
GO:0030234enzyme regulator activity4.27e-041.00e+006.0092313
GO:0006457protein folding4.28e-041.00e+003.49048149
GO:0031011Ino80 complex4.97e-041.00e+005.9022314
GO:0006310DNA recombination5.44e-041.00e+004.2283467
GO:0045445myoblast differentiation5.73e-041.00e+005.8022215
GO:0006289nucleotide-excision repair5.93e-041.00e+004.18531269
GO:0003697single-stranded DNA binding5.93e-041.00e+004.1853969
GO:0000398mRNA splicing, via spliceosome6.29e-041.00e+003.343412165
GO:0042176regulation of protein catabolic process6.54e-041.00e+005.7092316
GO:0005515protein binding6.83e-041.00e+000.772251726127
GO:0071013catalytic step 2 spliceosome8.80e-041.00e+003.9903779
GO:0042802identical protein binding1.01e-031.00e+002.354618491
GO:0005524ATP binding1.02e-031.00e+001.62810461354
GO:0006298mismatch repair1.03e-031.00e+005.3872620
GO:0000718nucleotide-excision repair, DNA damage removal1.14e-031.00e+005.3172521
GO:0006297nucleotide-excision repair, DNA gap filling1.25e-031.00e+005.2502522
GO:0032201telomere maintenance via semi-conservative replication1.25e-031.00e+005.2502722
GO:0006270DNA replication initiation1.25e-031.00e+005.2502522
GO:0043044ATP-dependent chromatin remodeling1.36e-031.00e+005.1852423
GO:0016363nuclear matrix1.37e-031.00e+003.77031192
GO:0016605PML body1.37e-031.00e+003.7703592
GO:0000722telomere maintenance via recombination1.74e-031.00e+005.0092726
GO:0004003ATP-dependent DNA helicase activity1.88e-031.00e+004.9542327
GO:0071339MLL1 complex1.88e-031.00e+004.9542327
GO:0043967histone H4 acetylation2.02e-031.00e+004.9022328
GO:0031492nucleosomal DNA binding2.02e-031.00e+004.9022428
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity2.39e-031.00e+008.709111
GO:0034602oxoglutarate dehydrogenase (NAD+) activity2.39e-031.00e+008.709111
GO:0070335aspartate binding2.39e-031.00e+008.709111
GO:0008262importin-alpha export receptor activity2.39e-031.00e+008.709111
GO:0008541proteasome regulatory particle, lid subcomplex2.39e-031.00e+008.709111
GO:0090230regulation of centromere complex assembly2.39e-031.00e+008.709111
GO:0004151dihydroorotase activity2.39e-031.00e+008.709111
GO:0004632phosphopantothenate--cysteine ligase activity2.39e-031.00e+008.709111
GO:0046940nucleoside monophosphate phosphorylation2.39e-031.00e+008.709111
GO:0019521D-gluconate metabolic process2.39e-031.00e+008.709111
GO:0004070aspartate carbamoyltransferase activity2.39e-031.00e+008.709111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity2.39e-031.00e+008.709111
GO:0030529ribonucleoprotein complex2.53e-031.00e+003.46138114
GO:0033572transferrin transport2.64e-031.00e+004.7092632
GO:0006325chromatin organization3.13e-031.00e+003.35134123
GO:0051084'de novo' posttranslational protein folding3.51e-031.00e+004.5002437
GO:0006284base-excision repair3.90e-031.00e+004.4242739
GO:0004832valine-tRNA ligase activity4.77e-031.00e+007.709112
GO:0045252oxoglutarate dehydrogenase complex4.77e-031.00e+007.709122
GO:0006233dTDP biosynthetic process4.77e-031.00e+007.709112
GO:0097286iron ion import4.77e-031.00e+007.709112
GO:0006407rRNA export from nucleus4.77e-031.00e+007.709112
GO:0006438valyl-tRNA aminoacylation4.77e-031.00e+007.709112
GO:0000466maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.77e-031.00e+007.709112
GO:0050145nucleoside phosphate kinase activity4.77e-031.00e+007.709112
GO:0061034olfactory bulb mitral cell layer development4.77e-031.00e+007.709112
GO:0000105histidine biosynthetic process4.77e-031.00e+007.709112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.77e-031.00e+007.709112
GO:0004998transferrin receptor activity4.77e-031.00e+007.709112
GO:0019322pentose biosynthetic process4.77e-031.00e+007.709112
GO:0031134sister chromatid biorientation4.77e-031.00e+007.709112
GO:0005055laminin receptor activity4.77e-031.00e+007.709112
GO:0004798thymidylate kinase activity4.77e-031.00e+007.709112
GO:0007127meiosis I4.77e-031.00e+007.709112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis4.77e-031.00e+007.709122
GO:0070409carbamoyl phosphate biosynthetic process4.77e-031.00e+007.709112
GO:0031100organ regeneration6.34e-031.00e+004.0652450
GO:0040008regulation of growth6.59e-031.00e+004.0372351
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity7.15e-031.00e+007.124113
GO:0070545PeBoW complex7.15e-031.00e+007.124113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb7.15e-031.00e+007.124113
GO:0000463maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)7.15e-031.00e+007.124113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity7.15e-031.00e+007.124113
GO:0006235dTTP biosynthetic process7.15e-031.00e+007.124113
GO:0071459protein localization to chromosome, centromeric region7.15e-031.00e+007.124113
GO:0071899negative regulation of estrogen receptor binding7.15e-031.00e+007.124113
GO:0071733transcriptional activation by promoter-enhancer looping7.15e-031.00e+007.124113
GO:0009051pentose-phosphate shunt, oxidative branch7.15e-031.00e+007.124113
GO:0044205'de novo' UMP biosynthetic process7.15e-031.00e+007.124113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle7.15e-031.00e+007.124113
GO:0030687preribosome, large subunit precursor7.15e-031.00e+007.124113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process7.15e-031.00e+007.124113
GO:0008283cell proliferation7.81e-031.00e+002.338412331
GO:0043231intracellular membrane-bounded organelle7.89e-031.00e+002.33448332
GO:0006879cellular iron ion homeostasis8.17e-031.00e+003.8762557
GO:0000723telomere maintenance8.74e-031.00e+003.8262859
GO:0031625ubiquitin protein ligase binding9.01e-031.00e+002.802313180
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)9.52e-031.00e+006.709114
GO:0000212meiotic spindle organization9.52e-031.00e+006.709114
GO:003068690S preribosome9.52e-031.00e+006.709114
GO:0071922regulation of cohesin localization to chromatin9.52e-031.00e+006.709114
GO:0019788NEDD8 ligase activity9.52e-031.00e+006.709114
GO:0007000nucleolus organization9.52e-031.00e+006.709114
GO:0016274protein-arginine N-methyltransferase activity9.52e-031.00e+006.709114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity9.52e-031.00e+006.709114
GO:0004329formate-tetrahydrofolate ligase activity9.52e-031.00e+006.709114
GO:0043141ATP-dependent 5'-3' DNA helicase activity9.52e-031.00e+006.709114
GO:0034969histone arginine methylation9.52e-031.00e+006.709114
GO:0006104succinyl-CoA metabolic process9.52e-031.00e+006.709114
GO:0006543glutamine catabolic process9.52e-031.00e+006.709114
GO:0009396folic acid-containing compound biosynthetic process9.52e-031.00e+006.709114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity9.52e-031.00e+006.709114
GO:0031467Cul7-RING ubiquitin ligase complex9.52e-031.00e+006.709114
GO:0043550regulation of lipid kinase activity9.52e-031.00e+006.709114
GO:0035189Rb-E2F complex9.52e-031.00e+006.709114
GO:0034349glial cell apoptotic process9.52e-031.00e+006.709114
GO:0034088maintenance of mitotic sister chromatid cohesion9.52e-031.00e+006.709114
GO:0006302double-strand break repair9.61e-031.00e+003.7552862
GO:0006338chromatin remodeling1.15e-021.00e+003.6222468
GO:0051414response to cortisol1.19e-021.00e+006.387115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.19e-021.00e+006.387125
GO:0001940male pronucleus1.19e-021.00e+006.387115
GO:0009086methionine biosynthetic process1.19e-021.00e+006.387115
GO:2000001regulation of DNA damage checkpoint1.19e-021.00e+006.387115
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.19e-021.00e+006.387115
GO:0031461cullin-RING ubiquitin ligase complex1.19e-021.00e+006.387115
GO:0071169establishment of protein localization to chromatin1.19e-021.00e+006.387115
GO:0048667cell morphogenesis involved in neuron differentiation1.19e-021.00e+006.387115
GO:0030891VCB complex1.19e-021.00e+006.387125
GO:0005827polar microtubule1.19e-021.00e+006.387115
GO:0006734NADH metabolic process1.19e-021.00e+006.387115
GO:0061133endopeptidase activator activity1.19e-021.00e+006.387115
GO:0030976thiamine pyrophosphate binding1.19e-021.00e+006.387115
GO:0044822poly(A) RNA binding1.29e-021.00e+001.4427501078
GO:0055086nucleobase-containing small molecule metabolic process1.31e-021.00e+003.5192573
GO:0006767water-soluble vitamin metabolic process1.38e-021.00e+003.4802375
GO:0007265Ras protein signal transduction1.38e-021.00e+003.4802375
GO:0043353enucleate erythrocyte differentiation1.43e-021.00e+006.124116
GO:0009108coenzyme biosynthetic process1.43e-021.00e+006.124116
GO:0045842positive regulation of mitotic metaphase/anaphase transition1.43e-021.00e+006.124116
GO:0021860pyramidal neuron development1.43e-021.00e+006.124116
GO:0031466Cul5-RING ubiquitin ligase complex1.43e-021.00e+006.124116
GO:0021695cerebellar cortex development1.43e-021.00e+006.124116
GO:0030957Tat protein binding1.43e-021.00e+006.124146
GO:0046134pyrimidine nucleoside biosynthetic process1.43e-021.00e+006.124116
GO:0008469histone-arginine N-methyltransferase activity1.43e-021.00e+006.124116
GO:0006766vitamin metabolic process1.49e-021.00e+003.4242378
GO:0007565female pregnancy1.56e-021.00e+003.3872280
GO:0010950positive regulation of endopeptidase activity1.66e-021.00e+005.902117
GO:0000028ribosomal small subunit assembly1.66e-021.00e+005.902117
GO:0002161aminoacyl-tRNA editing activity1.66e-021.00e+005.902127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.66e-021.00e+005.902117
GO:0001939female pronucleus1.66e-021.00e+005.902117
GO:0031462Cul2-RING ubiquitin ligase complex1.66e-021.00e+005.902127
GO:0033180proton-transporting V-type ATPase, V1 domain1.66e-021.00e+005.902127
GO:0035999tetrahydrofolate interconversion1.66e-021.00e+005.902117
GO:0072341modified amino acid binding1.66e-021.00e+005.902117
GO:0000930gamma-tubulin complex1.66e-021.00e+005.902117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.66e-021.00e+005.902117
GO:0016018cyclosporin A binding1.66e-021.00e+005.902117
GO:0005681spliceosomal complex1.68e-021.00e+003.3342383
GO:0008380RNA splicing1.78e-021.00e+002.436313232
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.90e-021.00e+005.709128
GO:0001055RNA polymerase II activity1.90e-021.00e+005.709138
GO:0070688MLL5-L complex1.90e-021.00e+005.709118
GO:0006554lysine catabolic process1.90e-021.00e+005.709128
GO:0045116protein neddylation1.90e-021.00e+005.709128
GO:0000800lateral element1.90e-021.00e+005.709118
GO:0006164purine nucleotide biosynthetic process1.90e-021.00e+005.709128
GO:0042470melanosome2.03e-021.00e+003.18521092
GO:0005200structural constituent of cytoskeleton2.08e-021.00e+003.1702793
GO:0016272prefoldin complex2.13e-021.00e+005.539119
GO:0014075response to amine2.13e-021.00e+005.539119
GO:0015937coenzyme A biosynthetic process2.13e-021.00e+005.539119
GO:0097284hepatocyte apoptotic process2.13e-021.00e+005.539129
GO:0006228UTP biosynthetic process2.13e-021.00e+005.539119
GO:0010389regulation of G2/M transition of mitotic cell cycle2.13e-021.00e+005.539119
GO:0000075cell cycle checkpoint2.13e-021.00e+005.539129
GO:0031000response to caffeine2.13e-021.00e+005.539129
GO:0051082unfolded protein binding2.16e-021.00e+003.1392695
GO:0070628proteasome binding2.36e-021.00e+005.3871110
GO:0046655folic acid metabolic process2.36e-021.00e+005.3871110
GO:0006450regulation of translational fidelity2.36e-021.00e+005.3871210
GO:0006268DNA unwinding involved in DNA replication2.36e-021.00e+005.3871210
GO:0015939pantothenate metabolic process2.36e-021.00e+005.3871110
GO:0021756striatum development2.36e-021.00e+005.3871110
GO:0006098pentose-phosphate shunt2.60e-021.00e+005.2501311
GO:0010569regulation of double-strand break repair via homologous recombination2.60e-021.00e+005.2501111
GO:0031571mitotic G1 DNA damage checkpoint2.60e-021.00e+005.2501311
GO:0042551neuron maturation2.60e-021.00e+005.2501211
GO:0001054RNA polymerase I activity2.60e-021.00e+005.2501311
GO:0045651positive regulation of macrophage differentiation2.60e-021.00e+005.2501211
GO:0045120pronucleus2.60e-021.00e+005.2501111
GO:0033762response to glucagon2.60e-021.00e+005.2501111
GO:0061136regulation of proteasomal protein catabolic process2.83e-021.00e+005.1241112
GO:00709353'-UTR-mediated mRNA stabilization2.83e-021.00e+005.1241212
GO:0051146striated muscle cell differentiation2.83e-021.00e+005.1241112
GO:0005736DNA-directed RNA polymerase I complex2.83e-021.00e+005.1241312
GO:0021794thalamus development2.83e-021.00e+005.1241112
GO:0042273ribosomal large subunit biogenesis3.06e-021.00e+005.0091413
GO:0045780positive regulation of bone resorption3.06e-021.00e+005.0091113
GO:0046939nucleotide phosphorylation3.06e-021.00e+005.0091113
GO:0008266poly(U) RNA binding3.06e-021.00e+005.0091113
GO:0072562blood microparticle3.13e-021.00e+002.85124116
GO:0007020microtubule nucleation3.30e-021.00e+004.9021114
GO:0007095mitotic G2 DNA damage checkpoint3.30e-021.00e+004.9021114
GO:0043234protein complex3.45e-021.00e+002.065317300
GO:0035066positive regulation of histone acetylation3.53e-021.00e+004.8021115
GO:0046961proton-transporting ATPase activity, rotational mechanism3.53e-021.00e+004.8021315
GO:0016514SWI/SNF complex3.53e-021.00e+004.8021315
GO:0006261DNA-dependent DNA replication3.53e-021.00e+004.8021215
GO:0005737cytoplasm3.54e-021.00e+000.65915983976
GO:0005665DNA-directed RNA polymerase II, core complex3.76e-021.00e+004.7091416
GO:0046034ATP metabolic process3.76e-021.00e+004.7091116
GO:0050998nitric-oxide synthase binding3.76e-021.00e+004.7091116
GO:0001673male germ cell nucleus3.76e-021.00e+004.7091116
GO:00061032-oxoglutarate metabolic process3.76e-021.00e+004.7091116
GO:0001056RNA polymerase III activity3.76e-021.00e+004.7091316
GO:0010243response to organonitrogen compound3.99e-021.00e+004.6221217
GO:0001829trophectodermal cell differentiation3.99e-021.00e+004.6221117
GO:0005666DNA-directed RNA polymerase III complex3.99e-021.00e+004.6221317
GO:0045070positive regulation of viral genome replication3.99e-021.00e+004.6221117
GO:0033365protein localization to organelle3.99e-021.00e+004.6221117
GO:0007126meiotic nuclear division3.99e-021.00e+004.6221117
GO:0000790nuclear chromatin4.01e-021.00e+002.65427133
GO:0070536protein K63-linked deubiquitination4.22e-021.00e+004.5391118
GO:0006386termination of RNA polymerase III transcription4.22e-021.00e+004.5391318
GO:0071392cellular response to estradiol stimulus4.22e-021.00e+004.5391118
GO:0006541glutamine metabolic process4.22e-021.00e+004.5391118
GO:0031122cytoplasmic microtubule organization4.22e-021.00e+004.5391218
GO:0035861site of double-strand break4.22e-021.00e+004.5391118
GO:0006385transcription elongation from RNA polymerase III promoter4.22e-021.00e+004.5391318
GO:0006303double-strand break repair via nonhomologous end joining4.22e-021.00e+004.5391318
GO:0015949nucleobase-containing small molecule interconversion4.22e-021.00e+004.5391218
GO:0000086G2/M transition of mitotic cell cycle4.23e-021.00e+002.61127137
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process4.45e-021.00e+004.4611119
GO:0016887ATPase activity4.63e-021.00e+002.53927144
GO:0015078hydrogen ion transmembrane transporter activity4.67e-021.00e+004.3871320
GO:2000134negative regulation of G1/S transition of mitotic cell cycle4.67e-021.00e+004.3871220
GO:0048873homeostasis of number of cells within a tissue4.67e-021.00e+004.3871120
GO:0005719nuclear euchromatin4.67e-021.00e+004.3871220
GO:0043021ribonucleoprotein complex binding4.90e-021.00e+004.3171121
GO:0071364cellular response to epidermal growth factor stimulus4.90e-021.00e+004.3171121
GO:0000793condensed chromosome4.90e-021.00e+004.3171121
GO:0030316osteoclast differentiation5.13e-021.00e+004.2501222
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle5.13e-021.00e+004.2501322
GO:0046686response to cadmium ion5.13e-021.00e+004.2501322
GO:0033574response to testosterone5.13e-021.00e+004.2501222
GO:0030863cortical cytoskeleton5.13e-021.00e+004.2501122
GO:0036464cytoplasmic ribonucleoprotein granule5.13e-021.00e+004.2501422
GO:0003723RNA binding5.24e-021.00e+001.822319355
GO:0031463Cul3-RING ubiquitin ligase complex5.36e-021.00e+004.1851223
GO:0043236laminin binding5.36e-021.00e+004.1851123
GO:0006513protein monoubiquitination5.36e-021.00e+004.1851123
GO:0045879negative regulation of smoothened signaling pathway5.36e-021.00e+004.1851123
GO:0000794condensed nuclear chromosome5.58e-021.00e+004.1241224
GO:0006206pyrimidine nucleobase metabolic process5.58e-021.00e+004.1241224
GO:0006611protein export from nucleus5.81e-021.00e+004.0651425
GO:0008536Ran GTPase binding5.81e-021.00e+004.0651225
GO:0005844polysome5.81e-021.00e+004.0651425
GO:0017144drug metabolic process5.81e-021.00e+004.0651125
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia6.04e-021.00e+004.0091226
GO:0006730one-carbon metabolic process6.04e-021.00e+004.0091126
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding6.09e-021.00e+002.31725168
GO:0034080CENP-A containing nucleosome assembly6.26e-021.00e+003.9541227
GO:0048565digestive tract development6.26e-021.00e+003.9541127
GO:0015991ATP hydrolysis coupled proton transport6.48e-021.00e+003.9021428
GO:0043022ribosome binding6.48e-021.00e+003.9021328
GO:0019894kinesin binding6.48e-021.00e+003.9021128
GO:0006099tricarboxylic acid cycle6.71e-021.00e+003.8511329
GO:0019005SCF ubiquitin ligase complex6.71e-021.00e+003.8511129
GO:0003730mRNA 3'-UTR binding6.71e-021.00e+003.8511229
GO:00063707-methylguanosine mRNA capping6.93e-021.00e+003.8021430
GO:0006360transcription from RNA polymerase I promoter6.93e-021.00e+003.8021430
GO:0042254ribosome biogenesis6.93e-021.00e+003.8021130
GO:0007346regulation of mitotic cell cycle6.93e-021.00e+003.8021330
GO:0007093mitotic cell cycle checkpoint7.15e-021.00e+003.7551231
GO:0050661NADP binding7.38e-021.00e+003.7091132
GO:0031397negative regulation of protein ubiquitination7.38e-021.00e+003.7091132
GO:0015992proton transport7.38e-021.00e+003.7091332
GO:0051219phosphoprotein binding7.38e-021.00e+003.7091332
GO:0034644cellular response to UV7.38e-021.00e+003.7091532
GO:0031072heat shock protein binding7.60e-021.00e+003.6651233
GO:0000413protein peptidyl-prolyl isomerization7.82e-021.00e+003.6221134
GO:0003755peptidyl-prolyl cis-trans isomerase activity7.82e-021.00e+003.6221134
GO:0051701interaction with host7.82e-021.00e+003.6221434
GO:0034332adherens junction organization8.26e-021.00e+003.5391136
GO:0004221ubiquitin thiolesterase activity8.26e-021.00e+003.5391236
GO:0051402neuron apoptotic process8.26e-021.00e+003.5391236
GO:0001895retina homeostasis8.26e-021.00e+003.5391136
GO:0003924GTPase activity8.46e-021.00e+002.04429203
GO:0001102RNA polymerase II activating transcription factor binding8.48e-021.00e+003.5001437
GO:0018107peptidyl-threonine phosphorylation8.48e-021.00e+003.5001137
GO:0070527platelet aggregation8.70e-021.00e+003.4611238
GO:0050681androgen receptor binding8.70e-021.00e+003.4611438
GO:0090382phagosome maturation8.70e-021.00e+003.4611538
GO:0021766hippocampus development8.92e-021.00e+003.4241439
GO:0006383transcription from RNA polymerase III promoter8.92e-021.00e+003.4241339
GO:0031490chromatin DNA binding8.92e-021.00e+003.4241239
GO:0006096glycolytic process8.92e-021.00e+003.4241439
GO:0022627cytosolic small ribosomal subunit8.92e-021.00e+003.4241339
GO:0007595lactation8.92e-021.00e+003.4241239
GO:0000781chromosome, telomeric region9.14e-021.00e+003.3871240
GO:0043195terminal bouton9.35e-021.00e+003.3511141
GO:0030521androgen receptor signaling pathway9.35e-021.00e+003.3511241
GO:0006418tRNA aminoacylation for protein translation9.57e-021.00e+003.3171542
GO:0005902microvillus9.57e-021.00e+003.3171242
GO:0035914skeletal muscle cell differentiation9.57e-021.00e+003.3171142
GO:0071363cellular response to growth factor stimulus9.57e-021.00e+003.3171242
GO:0006184GTP catabolic process9.69e-021.00e+001.92829220
GO:0014070response to organic cyclic compound9.79e-021.00e+003.2831343
GO:0048146positive regulation of fibroblast proliferation1.00e-011.00e+003.2501244
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding1.00e-011.00e+003.2501244
GO:0050434positive regulation of viral transcription1.00e-011.00e+003.2501544
GO:0015030Cajal body1.02e-011.00e+003.2171245
GO:0021762substantia nigra development1.04e-011.00e+003.1851146
GO:0001047core promoter binding1.04e-011.00e+003.1851246
GO:0007067mitotic nuclear division1.05e-011.00e+001.857213231
GO:0000079regulation of cyclin-dependent protein serine/threonine kinase activity1.06e-011.00e+003.1541347
GO:0005759mitochondrial matrix1.07e-011.00e+001.845212233
GO:0035690cellular response to drug1.13e-011.00e+003.0651250
GO:0044267cellular protein metabolic process1.14e-011.00e+001.343324495
GO:0006091generation of precursor metabolites and energy1.15e-011.00e+003.0371351
GO:0005905coated pit1.15e-011.00e+003.0371251
GO:0008168methyltransferase activity1.17e-011.00e+003.0091152
GO:0003725double-stranded RNA binding1.21e-011.00e+002.9541654
GO:0019900kinase binding1.21e-011.00e+002.9541154
GO:0050680negative regulation of epithelial cell proliferation1.21e-011.00e+002.9541154
GO:0000226microtubule cytoskeleton organization1.23e-011.00e+002.9281355
GO:0043627response to estrogen1.28e-011.00e+002.8761257
GO:0012505endomembrane system1.28e-011.00e+002.8761257
GO:0030097hemopoiesis1.30e-011.00e+002.8511358
GO:0008237metallopeptidase activity1.30e-011.00e+002.8511158
GO:0005840ribosome1.32e-011.00e+002.8261259
GO:0051087chaperone binding1.32e-011.00e+002.8261659
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.32e-011.00e+002.8261459
GO:0045216cell-cell junction organization1.32e-011.00e+002.8261259
GO:0031966mitochondrial membrane1.32e-011.00e+002.8261159
GO:0032481positive regulation of type I interferon production1.36e-011.00e+002.7781661
GO:0000166nucleotide binding1.37e-011.00e+001.62226272
GO:0005758mitochondrial intermembrane space1.38e-011.00e+002.7551162
GO:0019903protein phosphatase binding1.40e-011.00e+002.7321463
GO:0042995cell projection1.40e-011.00e+002.7321663
GO:0006469negative regulation of protein kinase activity1.44e-011.00e+002.6871265
GO:0001558regulation of cell growth1.46e-011.00e+002.6651466
GO:0006368transcription elongation from RNA polymerase II promoter1.48e-011.00e+002.6431667
GO:0019899enzyme binding1.51e-011.00e+001.539211288
GO:0034329cell junction assembly1.57e-011.00e+002.5591171
GO:0055037recycling endosome1.61e-011.00e+002.5191273
GO:0032355response to estradiol1.61e-011.00e+002.5191573
GO:0000785chromatin1.61e-011.00e+002.5191573
GO:0031175neuron projection development1.65e-011.00e+002.4801175
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.67e-011.00e+002.4611376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.69e-011.00e+002.4421577
GO:0006334nucleosome assembly1.73e-011.00e+002.4051479
GO:0019083viral transcription1.77e-011.00e+002.3691881
GO:0019901protein kinase binding1.78e-011.00e+001.387221320
GO:0045177apical part of cell1.79e-011.00e+002.3511182
GO:0001889liver development1.79e-011.00e+002.3511382
GO:0001726ruffle1.79e-011.00e+002.3511482
GO:0005525GTP binding1.84e-011.00e+001.351211328
GO:0047485protein N-terminus binding1.86e-011.00e+002.2831486
GO:0006898receptor-mediated endocytosis1.86e-011.00e+002.2831286
GO:0006415translational termination1.88e-011.00e+002.2661887
GO:0005813centrosome1.94e-011.00e+001.304212339
GO:0006928cellular component movement1.98e-011.00e+002.1851792
GO:0006414translational elongation2.00e-011.00e+002.17011193
GO:0001649osteoblast differentiation2.04e-011.00e+002.1391695
GO:0006364rRNA processing2.06e-011.00e+002.1241596
GO:0071456cellular response to hypoxia2.10e-011.00e+002.0941498
GO:0051726regulation of cell cycle2.17e-011.00e+002.03713102
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.21e-011.00e+002.00918104
GO:0014069postsynaptic density2.25e-011.00e+001.98111106
GO:0016023cytoplasmic membrane-bounded vesicle2.26e-011.00e+001.96813107
GO:0005815microtubule organizing center2.32e-011.00e+001.92814110
GO:0007155cell adhesion2.34e-011.00e+001.12428384
GO:0042127regulation of cell proliferation2.34e-011.00e+001.91514111
GO:0015630microtubule cytoskeleton2.36e-011.00e+001.90215112
GO:0005739mitochondrion2.38e-011.00e+000.6784241046
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.39e-011.00e+001.876110114
GO:0005819spindle2.39e-011.00e+001.87617114
GO:0019058viral life cycle2.41e-011.00e+001.864110115
GO:0044237cellular metabolic process2.47e-011.00e+001.82613118
GO:0007219Notch signaling pathway2.59e-011.00e+001.74314125
GO:0007050cell cycle arrest2.61e-011.00e+001.73217126
GO:0006511ubiquitin-dependent protein catabolic process2.63e-011.00e+001.72015127
GO:0006413translational initiation2.70e-011.00e+001.676112131
GO:0031982vesicle2.75e-011.00e+001.643110134
GO:0003735structural constituent of ribosome2.87e-011.00e+001.56918141
GO:0007507heart development2.87e-011.00e+001.56915141
GO:0008286insulin receptor signaling pathway2.93e-011.00e+001.53916144
GO:0061024membrane organization2.96e-011.00e+001.51915146
GO:0046777protein autophosphorylation3.16e-011.00e+001.40513158
GO:0055114oxidation-reduction process3.20e-011.00e+000.799211481
GO:0045893positive regulation of transcription, DNA-templated3.25e-011.00e+000.781217487
GO:0006397mRNA processing3.34e-011.00e+001.30813169
GO:0030424axon3.39e-011.00e+001.28313172
GO:0005768endosome3.42e-011.00e+001.26615174
GO:0016607nuclear speck3.44e-011.00e+001.25814175
GO:0007049cell cycle3.47e-011.00e+001.24113177
GO:0004672protein kinase activity3.48e-011.00e+001.23312178
GO:0055085transmembrane transport3.49e-011.00e+000.70328514
GO:0009897external side of plasma membrane3.56e-011.00e+001.19314183
GO:0015629actin cytoskeleton3.56e-011.00e+001.19315183
GO:0006367transcription initiation from RNA polymerase II promoter3.58e-011.00e+001.18518184
GO:0032403protein complex binding3.59e-011.00e+001.17817185
GO:0001701in utero embryonic development3.97e-011.00e+000.99516210
GO:0005765lysosomal membrane4.08e-011.00e+000.94115218
GO:0005622intracellular4.20e-011.00e+000.88915226
GO:0006412translation4.32e-011.00e+000.833115235
GO:0045087innate immune response4.36e-011.00e+000.442220616
GO:0003713transcription coactivator activity4.38e-011.00e+000.808110239
GO:0008134transcription factor binding4.47e-011.00e+000.76718246
GO:0043025neuronal cell body4.58e-011.00e+000.72014254
GO:0004842ubiquitin-protein transferase activity4.61e-011.00e+000.70914256
GO:0005794Golgi apparatus4.64e-011.00e+000.365214650
GO:0046872metal ion binding4.69e-011.00e+000.1924241465
GO:0005975carbohydrate metabolic process4.84e-011.00e+000.61115274
GO:0006357regulation of transcription from RNA polymerase II promoter4.85e-011.00e+000.60616275
GO:0007283spermatogenesis4.86e-011.00e+000.60116276
GO:0016567protein ubiquitination5.14e-011.00e+000.48515299
GO:0006200ATP catabolic process5.19e-011.00e+000.466114303
GO:0005856cytoskeleton5.28e-011.00e+000.42818311
GO:0007411axon guidance5.46e-011.00e+000.35619327
GO:0003682chromatin binding5.54e-011.00e+000.325112334
GO:0045944positive regulation of transcription from RNA polymerase II promoter5.84e-011.00e+000.045219811
GO:0005925focal adhesion5.92e-011.00e+000.178118370
GO:0008284positive regulation of cell proliferation6.13e-011.00e+000.09418392
GO:0003677DNA binding6.37e-011.00e+00-0.1063261351
GO:0009986cell surface6.40e-011.00e+00-0.01219422
GO:0045892negative regulation of transcription, DNA-templated6.42e-011.00e+00-0.019114424
GO:0006366transcription from RNA polymerase II promoter6.43e-011.00e+00-0.022112425
GO:0007596blood coagulation6.76e-011.00e+00-0.149114464
GO:0005615extracellular space7.05e-011.00e+00-0.2712171010
GO:0048471perinuclear region of cytoplasm7.20e-011.00e+00-0.322112523
GO:0008270zinc ion binding7.33e-011.00e+00-0.3502121067
GO:0006351transcription, DNA-templated7.44e-011.00e+00-0.3363251585
GO:0006355regulation of transcription, DNA-templated7.51e-011.00e+00-0.3992171104
GO:0003700sequence-specific DNA binding transcription factor activity8.40e-011.00e+00-0.838111748
GO:0005887integral component of plasma membrane9.06e-011.00e+00-1.19917961
GO:0005576extracellular region9.25e-011.00e+00-1.326191049
GO:0005886plasma membrane9.75e-011.00e+00-1.1753382834
GO:0016021integral component of membrane9.98e-011.00e+00-2.5691152483