int-snw-7879

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.947	5.37e-16	1.88e-03	3.29e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-7879 subnetwork

Genes (19)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
RBX1	9978	97	1.185	1.151	139	Yes	-
PAFAH1B1	5048	6	0.691	1.076	71	Yes	-
PSMA2	5683	60	1.093	1.106	89	Yes	-
[ RAB7A ]	7879	1	0.002	0.947	99	-	-
PSMB7	5695	48	0.982	1.052	57	Yes	-
PSMA1	5682	61	0.996	1.052	123	Yes	-
ATP6V1B2	526	44	0.881	1.076	278	-	-
RPSA	3921	156	1.327	1.151	152	Yes	-
PGD	5226	75	1.201	1.106	138	Yes	-
RPA2	6118	98	1.250	1.151	69	Yes	-
CDC16	8881	25	0.950	1.020	80	Yes	-
EEF2	1938	27	0.890	1.043	301	Yes	-
PPP2R1A	5518	9	0.644	0.985	249	Yes	-
PSMD3	5709	57	0.986	1.106	146	Yes	-
CLTC	1213	35	0.884	1.138	247	Yes	-
PSMB2	5690	18	0.877	1.026	117	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
HSPD1	3329	35	0.913	1.035	286	Yes	-

Interactions (50)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMA1	5682	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
EEF2	1938	PPP2R1A	5518	pp	--	int.Intact: MI:0914(association); int.I2D: YeastLow, BioGrid, HPRD, IntAct; int.HPRD: in vivo
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
EEF2	1938	PGD	5226	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMA2	5683	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PPP2R1A	5518	PSMB2	5690	pp	--	int.I2D: IntAct_Mouse
ATP6V1B2	526	CLTC	1213	pp	--	int.I2D: IntAct_Yeast
PPP2R1A	5518	PSMA1	5682	pp	--	int.I2D: IntAct_Mouse
ACTB	60	PPP2R1A	5518	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	CDC16	8881	pp	--	int.I2D: YeastLow
PPP2R1A	5518	PSMA2	5683	pp	--	int.I2D: IntAct_Mouse
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	ATP6V1B2	526	pp	--	int.I2D: BioGrid_Yeast
ATP6V1B2	526	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
PPP2R1A	5518	PSMB7	5695	pp	--	int.I2D: IntAct_Mouse
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
PSMA2	5683	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PGD	5226	PSMD11	5717	pp	--	int.I2D: YeastLow
ACTB	60	PSMA1	5682	pp	--	int.I2D: BioGrid_Yeast
EEF2	1938	HSPD1	3329	pp	--	int.I2D: YeastLow, YeastMedium
HSPD1	3329	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
PGD	5226	PPP2R1A	5518	pp	--	int.I2D: YeastLow
ACTB	60	PAFAH1B1	5048	pp	--	int.I2D: BioGrid_Yeast
PSMA2	5683	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACTB	60	EEF2	1938	pp	--	int.I2D: YeastLow, IntAct_Yeast
PSMA1	5682	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
PGD	5226	PSMD3	5709	pp	--	int.I2D: YeastLow
PSMA2	5683	PSMB2	5690	pp	--	int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core
ACTB	60	RAB7A	7879	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMB2	5690	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
PSMA1	5682	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
PSMA2	5683	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACTB	60	CLTC	1213	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
HSPD1	3329	PPP2R1A	5518	pp	--	int.Intact: MI:0914(association); int.I2D: HPRD, IntAct; int.HPRD: in vivo
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PPP2R1A	5518	RAB7A	7879	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid, HPRD, IntAct; int.HPRD: in vivo
PSMB2	5690	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
EEF2	1938	PSMD3	5709	pp	--	int.I2D: Krogan_NonCore
ACTB	60	HSPD1	3329	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow
ATP6V1B2	526	CDC16	8881	pp	--	int.I2D: IntAct_Yeast
PSMB7	5695	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
PAFAH1B1	5048	RAB7A	7879	pp	--	int.I2D: BioGrid_Yeast

Related GO terms (363)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.31e-12	1.89e-08	6.353	7	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.24e-12	3.23e-08	6.246	7	22	70
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.36e-12	4.84e-08	6.166	7	22	74
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	5.39e-12	7.77e-08	6.072	7	23	79
GO:0005829	cytosol	1.28e-11	1.85e-07	2.370	17	132	2496
GO:0000278	mitotic cell cycle	1.42e-11	2.05e-07	4.279	10	48	391
GO:0006521	regulation of cellular amino acid metabolic process	3.34e-11	4.81e-07	6.509	6	17	50
GO:0000502	proteasome complex	8.45e-11	1.22e-06	6.295	6	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.56e-10	2.25e-06	6.153	6	19	64
GO:0016071	mRNA metabolic process	1.88e-10	2.71e-06	4.767	8	31	223
GO:0070062	extracellular vesicular exosome	1.93e-10	2.79e-06	2.339	16	104	2400
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	3.22e-10	4.65e-06	5.983	6	20	72
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	4.15e-10	5.98e-06	5.924	6	20	75
GO:0016070	RNA metabolic process	4.24e-10	6.12e-06	4.620	8	32	247
GO:0000082	G1/S transition of mitotic cell cycle	4.95e-10	7.14e-06	5.156	7	32	149
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.45e-09	2.09e-05	5.630	6	21	92
GO:0000209	protein polyubiquitination	5.92e-09	8.54e-05	5.295	6	20	116
GO:0005839	proteasome core complex	6.50e-09	9.38e-05	7.398	4	8	18
GO:0016032	viral process	8.11e-09	1.17e-04	3.677	9	55	534
GO:0004298	threonine-type endopeptidase activity	8.23e-09	1.19e-04	7.320	4	8	19
GO:0042981	regulation of apoptotic process	2.78e-08	4.01e-04	4.924	6	24	150
GO:0010467	gene expression	5.73e-08	8.26e-04	3.352	9	59	669
GO:0034641	cellular nitrogen compound metabolic process	6.07e-08	8.76e-04	4.735	6	20	171
GO:0005654	nucleoplasm	2.68e-07	3.86e-03	2.811	10	76	1082
GO:0043066	negative regulation of apoptotic process	6.70e-07	9.67e-03	3.648	7	31	424
GO:0006915	apoptotic process	4.05e-06	5.84e-02	3.259	7	33	555
GO:0019773	proteasome core complex, alpha-subunit complex	4.58e-05	6.61e-01	7.568	2	4	8
GO:0005838	proteasome regulatory particle	1.08e-04	1.00e+00	6.983	2	7	12
GO:0016020	membrane	1.20e-04	1.00e+00	2.023	9	90	1681
GO:0005515	protein binding	1.85e-04	1.00e+00	1.012	16	184	6024
GO:0042470	melanosome	2.19e-04	1.00e+00	4.645	3	9	91
GO:0022624	proteasome accessory complex	2.21e-04	1.00e+00	6.481	2	8	17
GO:0005844	polysome	4.09e-04	1.00e+00	6.045	2	4	23
GO:0044281	small molecule metabolic process	5.91e-04	1.00e+00	2.134	7	58	1211
GO:0033572	transferrin transport	7.00e-04	1.00e+00	5.661	2	5	30
GO:0090382	phagosome maturation	1.01e-03	1.00e+00	5.398	2	5	36
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.32e-03	1.00e+00	9.568	1	1	1
GO:0000235	astral microtubule	1.32e-03	1.00e+00	9.568	1	1	1
GO:0048291	isotype switching to IgG isotypes	1.32e-03	1.00e+00	9.568	1	1	1
GO:0007174	epidermal growth factor catabolic process	1.32e-03	1.00e+00	9.568	1	1	1
GO:0051660	establishment of centrosome localization	1.32e-03	1.00e+00	9.568	1	1	1
GO:0070262	peptidyl-serine dephosphorylation	1.32e-03	1.00e+00	9.568	1	1	1
GO:0019521	D-gluconate metabolic process	1.32e-03	1.00e+00	9.568	1	1	1
GO:0002368	B cell cytokine production	1.32e-03	1.00e+00	9.568	1	1	1
GO:0046469	platelet activating factor metabolic process	1.32e-03	1.00e+00	9.568	1	1	1
GO:0003725	double-stranded RNA binding	2.10e-03	1.00e+00	4.868	2	5	52
GO:0051081	nuclear envelope disassembly	2.63e-03	1.00e+00	8.568	1	2	2
GO:0006407	rRNA export from nucleus	2.63e-03	1.00e+00	8.568	1	1	2
GO:0036035	osteoclast development	2.63e-03	1.00e+00	8.568	1	2	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.63e-03	1.00e+00	8.568	1	1	2
GO:0019322	pentose biosynthetic process	2.63e-03	1.00e+00	8.568	1	2	2
GO:0005055	laminin receptor activity	2.63e-03	1.00e+00	8.568	1	1	2
GO:0021540	corpus callosum morphogenesis	2.63e-03	1.00e+00	8.568	1	1	2
GO:0007067	mitotic nuclear division	3.09e-03	1.00e+00	3.327	3	14	227
GO:0003697	single-stranded DNA binding	3.56e-03	1.00e+00	4.481	2	5	68
GO:0090383	phagosome acidification	3.95e-03	1.00e+00	7.983	1	1	3
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity	3.95e-03	1.00e+00	7.983	1	1	3
GO:1900126	negative regulation of hyaluronan biosynthetic process	3.95e-03	1.00e+00	7.983	1	2	3
GO:0006458	'de novo' protein folding	3.95e-03	1.00e+00	7.983	1	1	3
GO:0090385	phagosome-lysosome fusion	3.95e-03	1.00e+00	7.983	1	1	3
GO:0009051	pentose-phosphate shunt, oxidative branch	3.95e-03	1.00e+00	7.983	1	2	3
GO:0030135	coated vesicle	3.95e-03	1.00e+00	7.983	1	1	3
GO:0071439	clathrin complex	3.95e-03	1.00e+00	7.983	1	2	3
GO:0045505	dynein intermediate chain binding	3.95e-03	1.00e+00	7.983	1	1	3
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	5.26e-03	1.00e+00	7.568	1	1	4
GO:0030686	90S preribosome	5.26e-03	1.00e+00	7.568	1	1	4
GO:0032051	clathrin light chain binding	5.26e-03	1.00e+00	7.568	1	1	4
GO:0019788	NEDD8 ligase activity	5.26e-03	1.00e+00	7.568	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	5.26e-03	1.00e+00	7.568	1	1	4
GO:1903077	negative regulation of protein localization to plasma membrane	5.26e-03	1.00e+00	7.568	1	1	4
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	6.15e-03	1.00e+00	4.076	2	7	90
GO:0043234	protein complex	6.44e-03	1.00e+00	2.949	3	18	295
GO:0006414	translational elongation	6.55e-03	1.00e+00	4.029	2	13	93
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	6.57e-03	1.00e+00	7.246	1	3	5
GO:0019932	second-messenger-mediated signaling	6.57e-03	1.00e+00	7.246	1	1	5
GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein	6.57e-03	1.00e+00	7.246	1	1	5
GO:2000001	regulation of DNA damage checkpoint	6.57e-03	1.00e+00	7.246	1	1	5
GO:0031023	microtubule organizing center organization	6.57e-03	1.00e+00	7.246	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	6.57e-03	1.00e+00	7.246	1	1	5
GO:0043248	proteasome assembly	6.57e-03	1.00e+00	7.246	1	1	5
GO:0046696	lipopolysaccharide receptor complex	6.57e-03	1.00e+00	7.246	1	1	5
GO:0030891	VCB complex	6.57e-03	1.00e+00	7.246	1	2	5
GO:0000730	DNA recombinase assembly	6.57e-03	1.00e+00	7.246	1	1	5
GO:0019901	protein kinase binding	7.85e-03	1.00e+00	2.845	3	21	317
GO:0007097	nuclear migration	7.88e-03	1.00e+00	6.983	1	1	6
GO:0003688	DNA replication origin binding	7.88e-03	1.00e+00	6.983	1	2	6
GO:0030130	clathrin coat of trans-Golgi network vesicle	7.88e-03	1.00e+00	6.983	1	3	6
GO:0030118	clathrin coat	7.88e-03	1.00e+00	6.983	1	2	6
GO:0001667	ameboidal-type cell migration	7.88e-03	1.00e+00	6.983	1	1	6
GO:0097208	alveolar lamellar body	7.88e-03	1.00e+00	6.983	1	1	6
GO:0031466	Cul5-RING ubiquitin ligase complex	7.88e-03	1.00e+00	6.983	1	1	6
GO:0008090	retrograde axon cargo transport	7.88e-03	1.00e+00	6.983	1	2	6
GO:0030957	Tat protein binding	7.88e-03	1.00e+00	6.983	1	3	6
GO:0034452	dynactin binding	7.88e-03	1.00e+00	6.983	1	1	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	7.88e-03	1.00e+00	6.983	1	1	6
GO:0005813	centrosome	8.48e-03	1.00e+00	2.804	3	14	326
GO:0015630	microtubule cytoskeleton	9.06e-03	1.00e+00	3.787	2	4	110
GO:0001961	positive regulation of cytokine-mediated signaling pathway	9.19e-03	1.00e+00	6.761	1	1	7
GO:0000028	ribosomal small subunit assembly	9.19e-03	1.00e+00	6.761	1	1	7
GO:0031462	Cul2-RING ubiquitin ligase complex	9.19e-03	1.00e+00	6.761	1	2	7
GO:0033180	proton-transporting V-type ATPase, V1 domain	9.19e-03	1.00e+00	6.761	1	2	7
GO:2000785	regulation of autophagic vacuole assembly	9.19e-03	1.00e+00	6.761	1	1	7
GO:0030132	clathrin coat of coated pit	9.19e-03	1.00e+00	6.761	1	2	7
GO:0017145	stem cell division	9.19e-03	1.00e+00	6.761	1	1	7
GO:0030529	ribonucleoprotein complex	9.38e-03	1.00e+00	3.761	2	8	112
GO:0005819	spindle	9.38e-03	1.00e+00	3.761	2	7	112
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	9.70e-03	1.00e+00	3.735	2	11	114
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	1.05e-02	1.00e+00	6.568	1	2	8
GO:0070688	MLL5-L complex	1.05e-02	1.00e+00	6.568	1	1	8
GO:0045116	protein neddylation	1.05e-02	1.00e+00	6.568	1	2	8
GO:0031512	motile primary cilium	1.05e-02	1.00e+00	6.568	1	1	8
GO:0051604	protein maturation	1.05e-02	1.00e+00	6.568	1	1	8
GO:0008494	translation activator activity	1.18e-02	1.00e+00	6.398	1	1	9
GO:0032319	regulation of Rho GTPase activity	1.18e-02	1.00e+00	6.398	1	2	9
GO:0021895	cerebral cortex neuron differentiation	1.18e-02	1.00e+00	6.398	1	1	9
GO:0006098	pentose-phosphate shunt	1.31e-02	1.00e+00	6.246	1	4	10
GO:0010569	regulation of double-strand break repair via homologous recombination	1.31e-02	1.00e+00	6.246	1	1	10
GO:0043032	positive regulation of macrophage activation	1.31e-02	1.00e+00	6.246	1	1	10
GO:0001675	acrosome assembly	1.31e-02	1.00e+00	6.246	1	1	10
GO:0007084	mitotic nuclear envelope reassembly	1.31e-02	1.00e+00	6.246	1	1	10
GO:0006622	protein targeting to lysosome	1.31e-02	1.00e+00	6.246	1	1	10
GO:0000086	G2/M transition of mitotic cell cycle	1.36e-02	1.00e+00	3.481	2	9	136
GO:0045502	dynein binding	1.44e-02	1.00e+00	6.109	1	2	11
GO:0032727	positive regulation of interferon-alpha production	1.44e-02	1.00e+00	6.109	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.44e-02	1.00e+00	6.109	1	4	11
GO:0021819	layer formation in cerebral cortex	1.44e-02	1.00e+00	6.109	1	1	11
GO:0061024	membrane organization	1.53e-02	1.00e+00	3.388	2	7	145
GO:0047496	vesicle transport along microtubule	1.57e-02	1.00e+00	5.983	1	2	12
GO:1903543	positive regulation of exosomal secretion	1.57e-02	1.00e+00	5.983	1	1	12
GO:0006275	regulation of DNA replication	1.57e-02	1.00e+00	5.983	1	2	12
GO:0030111	regulation of Wnt signaling pathway	1.57e-02	1.00e+00	5.983	1	1	12
GO:0005634	nucleus	1.59e-02	1.00e+00	0.873	11	136	4559
GO:0006672	ceramide metabolic process	1.70e-02	1.00e+00	5.868	1	1	13
GO:0005662	DNA replication factor A complex	1.70e-02	1.00e+00	5.868	1	1	13
GO:0030234	enzyme regulator activity	1.70e-02	1.00e+00	5.868	1	3	13
GO:0001530	lipopolysaccharide binding	1.70e-02	1.00e+00	5.868	1	3	13
GO:0051131	chaperone-mediated protein complex assembly	1.70e-02	1.00e+00	5.868	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	1.83e-02	1.00e+00	5.761	1	4	14
GO:0019226	transmission of nerve impulse	1.83e-02	1.00e+00	5.761	1	1	14
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	1.96e-02	1.00e+00	5.661	1	2	15
GO:0042026	protein refolding	1.96e-02	1.00e+00	5.661	1	2	15
GO:0046034	ATP metabolic process	1.96e-02	1.00e+00	5.661	1	1	15
GO:0045022	early endosome to late endosome transport	1.96e-02	1.00e+00	5.661	1	1	15
GO:0030904	retromer complex	1.96e-02	1.00e+00	5.661	1	2	15
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1.96e-02	1.00e+00	5.661	1	3	15
GO:0048854	brain morphogenesis	1.96e-02	1.00e+00	5.661	1	1	15
GO:0030424	axon	1.98e-02	1.00e+00	3.193	2	4	166
GO:0007405	neuroblast proliferation	2.09e-02	1.00e+00	5.568	1	1	16
GO:0042176	regulation of protein catabolic process	2.09e-02	1.00e+00	5.568	1	3	16
GO:0050998	nitric-oxide synthase binding	2.09e-02	1.00e+00	5.568	1	1	16
GO:0043274	phospholipase binding	2.09e-02	1.00e+00	5.568	1	1	16
GO:0000132	establishment of mitotic spindle orientation	2.09e-02	1.00e+00	5.568	1	1	16
GO:0010243	response to organonitrogen compound	2.22e-02	1.00e+00	5.481	1	3	17
GO:0003746	translation elongation factor activity	2.22e-02	1.00e+00	5.481	1	3	17
GO:0050870	positive regulation of T cell activation	2.22e-02	1.00e+00	5.481	1	1	17
GO:0031625	ubiquitin protein ligase binding	2.26e-02	1.00e+00	3.092	2	14	178
GO:0044267	cellular protein metabolic process	2.31e-02	1.00e+00	2.264	3	29	474
GO:0035861	site of double-strand break	2.35e-02	1.00e+00	5.398	1	1	18
GO:0007088	regulation of mitosis	2.35e-02	1.00e+00	5.398	1	1	18
GO:0045773	positive regulation of axon extension	2.35e-02	1.00e+00	5.398	1	4	18
GO:0015078	hydrogen ion transmembrane transporter activity	2.48e-02	1.00e+00	5.320	1	3	19
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.48e-02	1.00e+00	5.320	1	1	19
GO:0048863	stem cell differentiation	2.48e-02	1.00e+00	5.320	1	1	19
GO:0032733	positive regulation of interleukin-10 production	2.48e-02	1.00e+00	5.320	1	1	19
GO:0045453	bone resorption	2.48e-02	1.00e+00	5.320	1	2	19
GO:0009306	protein secretion	2.60e-02	1.00e+00	5.246	1	1	20
GO:0008601	protein phosphatase type 2A regulator activity	2.60e-02	1.00e+00	5.246	1	2	20
GO:0005680	anaphase-promoting complex	2.60e-02	1.00e+00	5.246	1	4	20
GO:0006298	mismatch repair	2.60e-02	1.00e+00	5.246	1	3	20
GO:0000159	protein phosphatase type 2A complex	2.60e-02	1.00e+00	5.246	1	2	20
GO:0003924	GTPase activity	2.73e-02	1.00e+00	2.946	2	12	197
GO:0042100	B cell proliferation	2.73e-02	1.00e+00	5.176	1	1	21
GO:0045595	regulation of cell differentiation	2.73e-02	1.00e+00	5.176	1	1	21
GO:0000718	nucleotide-excision repair, DNA damage removal	2.73e-02	1.00e+00	5.176	1	4	21
GO:0032201	telomere maintenance via semi-conservative replication	2.73e-02	1.00e+00	5.176	1	5	21
GO:0003823	antigen binding	2.86e-02	1.00e+00	5.109	1	1	22
GO:0006297	nucleotide-excision repair, DNA gap filling	2.86e-02	1.00e+00	5.109	1	3	22
GO:0030863	cortical cytoskeleton	2.86e-02	1.00e+00	5.109	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.86e-02	1.00e+00	5.109	1	4	22
GO:0005765	lysosomal membrane	2.88e-02	1.00e+00	2.903	2	5	203
GO:0031463	Cul3-RING ubiquitin ligase complex	2.99e-02	1.00e+00	5.045	1	3	23
GO:0043236	laminin binding	2.99e-02	1.00e+00	5.045	1	1	23
GO:0006513	protein monoubiquitination	2.99e-02	1.00e+00	5.045	1	1	23
GO:0046329	negative regulation of JNK cascade	2.99e-02	1.00e+00	5.045	1	1	23
GO:0043044	ATP-dependent chromatin remodeling	2.99e-02	1.00e+00	5.045	1	4	23
GO:0006184	GTP catabolic process	3.17e-02	1.00e+00	2.827	2	12	214
GO:0000722	telomere maintenance via recombination	3.24e-02	1.00e+00	4.924	1	5	25
GO:0042113	B cell activation	3.24e-02	1.00e+00	4.924	1	2	25
GO:0032735	positive regulation of interleukin-12 production	3.24e-02	1.00e+00	4.924	1	1	25
GO:0045931	positive regulation of mitotic cell cycle	3.37e-02	1.00e+00	4.868	1	1	26
GO:0070979	protein K11-linked ubiquitination	3.37e-02	1.00e+00	4.868	1	6	26
GO:0015991	ATP hydrolysis coupled proton transport	3.37e-02	1.00e+00	4.868	1	4	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3.37e-02	1.00e+00	4.868	1	3	26
GO:0010033	response to organic substance	3.50e-02	1.00e+00	4.813	1	2	27
GO:0050661	NADP binding	3.50e-02	1.00e+00	4.813	1	2	27
GO:0000188	inactivation of MAPK activity	3.50e-02	1.00e+00	4.813	1	1	27
GO:0007017	microtubule-based process	3.50e-02	1.00e+00	4.813	1	3	27
GO:0043022	ribosome binding	3.50e-02	1.00e+00	4.813	1	3	27
GO:0031492	nucleosomal DNA binding	3.50e-02	1.00e+00	4.813	1	4	27
GO:0006412	translation	3.62e-02	1.00e+00	2.723	2	20	230
GO:0031252	cell leading edge	3.63e-02	1.00e+00	4.761	1	4	28
GO:0010977	negative regulation of neuron projection development	3.63e-02	1.00e+00	4.761	1	2	28
GO:0005875	microtubule associated complex	3.63e-02	1.00e+00	4.761	1	2	28
GO:0030669	clathrin-coated endocytic vesicle membrane	3.63e-02	1.00e+00	4.761	1	4	28
GO:0019894	kinesin binding	3.63e-02	1.00e+00	4.761	1	1	28
GO:0019005	SCF ubiquitin ligase complex	3.75e-02	1.00e+00	4.710	1	1	29
GO:0015992	proton transport	3.75e-02	1.00e+00	4.710	1	3	29
GO:0008333	endosome to lysosome transport	3.75e-02	1.00e+00	4.710	1	1	29
GO:0048365	Rac GTPase binding	3.75e-02	1.00e+00	4.710	1	2	29
GO:0006271	DNA strand elongation involved in DNA replication	3.88e-02	1.00e+00	4.661	1	7	30
GO:0031623	receptor internalization	4.01e-02	1.00e+00	4.614	1	2	31
GO:0007094	mitotic spindle assembly checkpoint	4.01e-02	1.00e+00	4.614	1	4	31
GO:0051219	phosphoprotein binding	4.13e-02	1.00e+00	4.568	1	2	32
GO:0051701	interaction with host	4.13e-02	1.00e+00	4.568	1	4	32
GO:0045335	phagocytic vesicle	4.26e-02	1.00e+00	4.524	1	2	33
GO:0032588	trans-Golgi network membrane	4.39e-02	1.00e+00	4.481	1	2	34
GO:0007611	learning or memory	4.39e-02	1.00e+00	4.481	1	2	34
GO:0001895	retina homeostasis	4.39e-02	1.00e+00	4.481	1	1	34
GO:0005876	spindle microtubule	4.39e-02	1.00e+00	4.481	1	2	34
GO:0006281	DNA repair	4.56e-02	1.00e+00	2.540	2	18	261
GO:0044822	poly(A) RNA binding	4.57e-02	1.00e+00	1.524	4	49	1056
GO:0034332	adherens junction organization	4.64e-02	1.00e+00	4.398	1	1	36
GO:0032755	positive regulation of interleukin-6 production	4.64e-02	1.00e+00	4.398	1	2	36
GO:0051084	'de novo' posttranslational protein folding	4.77e-02	1.00e+00	4.359	1	4	37
GO:0006284	base-excision repair	4.77e-02	1.00e+00	4.359	1	3	37
GO:0021766	hippocampus development	4.89e-02	1.00e+00	4.320	1	4	38
GO:0005902	microvillus	4.89e-02	1.00e+00	4.320	1	2	38
GO:0070527	platelet aggregation	4.89e-02	1.00e+00	4.320	1	2	38
GO:0000781	chromosome, telomeric region	5.02e-02	1.00e+00	4.283	1	3	39
GO:0032729	positive regulation of interferon-gamma production	5.02e-02	1.00e+00	4.283	1	2	39
GO:0022627	cytosolic small ribosomal subunit	5.02e-02	1.00e+00	4.283	1	4	39
GO:0050885	neuromuscular process controlling balance	5.14e-02	1.00e+00	4.246	1	1	40
GO:0042147	retrograde transport, endosome to Golgi	5.27e-02	1.00e+00	4.211	1	3	41
GO:0042110	T cell activation	5.39e-02	1.00e+00	4.176	1	3	42
GO:0030136	clathrin-coated vesicle	5.39e-02	1.00e+00	4.176	1	4	42
GO:0004722	protein serine/threonine phosphatase activity	5.39e-02	1.00e+00	4.176	1	1	42
GO:0021987	cerebral cortex development	5.39e-02	1.00e+00	4.176	1	3	42
GO:0030155	regulation of cell adhesion	5.39e-02	1.00e+00	4.176	1	2	42
GO:0006892	post-Golgi vesicle-mediated transport	5.52e-02	1.00e+00	4.142	1	3	43
GO:0014070	response to organic cyclic compound	5.52e-02	1.00e+00	4.142	1	4	43
GO:0021762	substantia nigra development	5.64e-02	1.00e+00	4.109	1	2	44
GO:0005871	kinesin complex	5.64e-02	1.00e+00	4.109	1	3	44
GO:0045727	positive regulation of translation	5.64e-02	1.00e+00	4.109	1	3	44
GO:0008344	adult locomotory behavior	5.64e-02	1.00e+00	4.109	1	1	44
GO:0005730	nucleolus	5.66e-02	1.00e+00	1.210	5	69	1641
GO:0006283	transcription-coupled nucleotide-excision repair	5.89e-02	1.00e+00	4.045	1	7	46
GO:0019003	GDP binding	6.02e-02	1.00e+00	4.014	1	2	47
GO:0030670	phagocytic vesicle membrane	6.02e-02	1.00e+00	4.014	1	3	47
GO:0016042	lipid catabolic process	6.14e-02	1.00e+00	3.983	1	2	48
GO:0005525	GTP binding	6.19e-02	1.00e+00	2.292	2	12	310
GO:0003684	damaged DNA binding	6.27e-02	1.00e+00	3.953	1	7	49
GO:0006986	response to unfolded protein	6.39e-02	1.00e+00	3.924	1	2	50
GO:0000775	chromosome, centromeric region	6.39e-02	1.00e+00	3.924	1	2	50
GO:0005905	coated pit	6.39e-02	1.00e+00	3.924	1	3	50
GO:0040008	regulation of growth	6.39e-02	1.00e+00	3.924	1	5	50
GO:0043231	intracellular membrane-bounded organelle	6.48e-02	1.00e+00	2.255	2	9	318
GO:0006879	cellular iron ion homeostasis	6.51e-02	1.00e+00	3.896	1	4	51
GO:0000226	microtubule cytoskeleton organization	6.64e-02	1.00e+00	3.868	1	3	52
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	6.76e-02	1.00e+00	3.840	1	5	53
GO:0045216	cell-cell junction organization	6.88e-02	1.00e+00	3.813	1	2	54
GO:0000932	cytoplasmic mRNA processing body	6.88e-02	1.00e+00	3.813	1	3	54
GO:0002244	hematopoietic progenitor cell differentiation	6.88e-02	1.00e+00	3.813	1	1	54
GO:0002039	p53 binding	7.01e-02	1.00e+00	3.787	1	7	55
GO:0000724	double-strand break repair via homologous recombination	7.01e-02	1.00e+00	3.787	1	3	55
GO:0000723	telomere maintenance	7.13e-02	1.00e+00	3.761	1	6	56
GO:0012505	endomembrane system	7.13e-02	1.00e+00	3.761	1	2	56
GO:0051087	chaperone binding	7.50e-02	1.00e+00	3.686	1	6	59
GO:0007059	chromosome segregation	7.86e-02	1.00e+00	3.614	1	4	62
GO:0006302	double-strand break repair	7.86e-02	1.00e+00	3.614	1	4	62
GO:0019903	protein phosphatase binding	7.86e-02	1.00e+00	3.614	1	4	62
GO:0030141	secretory granule	7.86e-02	1.00e+00	3.614	1	2	62
GO:0000776	kinetochore	7.99e-02	1.00e+00	3.591	1	4	63
GO:0005925	focal adhesion	8.27e-02	1.00e+00	2.052	2	19	366
GO:0006289	nucleotide-excision repair	8.59e-02	1.00e+00	3.481	1	11	68
GO:0034329	cell junction assembly	8.59e-02	1.00e+00	3.481	1	1	68
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	9.32e-02	1.00e+00	3.359	1	6	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	9.44e-02	1.00e+00	3.339	1	2	75
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	9.68e-02	1.00e+00	3.301	1	7	77
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.00e-01	1.00e+00	3.246	1	3	80
GO:0001726	ruffle	1.00e-01	1.00e+00	3.246	1	4	80
GO:0019083	viral transcription	1.02e-01	1.00e+00	3.228	1	10	81
GO:0006898	receptor-mediated endocytosis	1.05e-01	1.00e+00	3.176	1	3	84
GO:0047485	protein N-terminus binding	1.07e-01	1.00e+00	3.142	1	5	86
GO:0006415	translational termination	1.09e-01	1.00e+00	3.125	1	10	87
GO:0050821	protein stabilization	1.10e-01	1.00e+00	3.109	1	2	88
GO:0016605	PML body	1.10e-01	1.00e+00	3.109	1	3	88
GO:0006928	cellular component movement	1.13e-01	1.00e+00	3.060	1	7	91
GO:0005200	structural constituent of cytoskeleton	1.13e-01	1.00e+00	3.060	1	8	91
GO:0001649	osteoblast differentiation	1.15e-01	1.00e+00	3.045	1	6	92
GO:0071456	cellular response to hypoxia	1.15e-01	1.00e+00	3.045	1	6	92
GO:0001764	neuron migration	1.16e-01	1.00e+00	3.029	1	3	93
GO:0051082	unfolded protein binding	1.16e-01	1.00e+00	3.029	1	5	93
GO:0005770	late endosome	1.16e-01	1.00e+00	3.029	1	1	93
GO:0030426	growth cone	1.19e-01	1.00e+00	2.983	1	5	96
GO:0006470	protein dephosphorylation	1.22e-01	1.00e+00	2.953	1	1	98
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	1.29e-01	1.00e+00	2.868	1	10	104
GO:0005938	cell cortex	1.29e-01	1.00e+00	2.868	1	3	104
GO:0014069	postsynaptic density	1.30e-01	1.00e+00	2.854	1	3	105
GO:0006897	endocytosis	1.31e-01	1.00e+00	2.840	1	8	106
GO:0030308	negative regulation of cell growth	1.35e-01	1.00e+00	2.787	1	6	110
GO:0006461	protein complex assembly	1.37e-01	1.00e+00	2.774	1	6	111
GO:0072562	blood microparticle	1.37e-01	1.00e+00	2.774	1	3	111
GO:0005635	nuclear envelope	1.39e-01	1.00e+00	2.748	1	6	113
GO:0019058	viral life cycle	1.41e-01	1.00e+00	2.723	1	13	115
GO:0006325	chromatin organization	1.45e-01	1.00e+00	2.686	1	5	118
GO:0007219	Notch signaling pathway	1.47e-01	1.00e+00	2.661	1	5	120
GO:0006260	DNA replication	1.48e-01	1.00e+00	2.649	1	9	121
GO:0008201	heparin binding	1.49e-01	1.00e+00	2.637	1	4	122
GO:0030036	actin cytoskeleton organization	1.50e-01	1.00e+00	2.626	1	5	123
GO:0009615	response to virus	1.54e-01	1.00e+00	2.591	1	5	126
GO:0006511	ubiquitin-dependent protein catabolic process	1.54e-01	1.00e+00	2.591	1	5	126
GO:0000790	nuclear chromatin	1.57e-01	1.00e+00	2.557	1	9	129
GO:0006413	translational initiation	1.59e-01	1.00e+00	2.535	1	17	131
GO:0031982	vesicle	1.59e-01	1.00e+00	2.535	1	9	131
GO:0003735	structural constituent of ribosome	1.66e-01	1.00e+00	2.470	1	10	137
GO:0016887	ATPase activity	1.69e-01	1.00e+00	2.439	1	7	140
GO:0008286	insulin receptor signaling pathway	1.71e-01	1.00e+00	2.418	1	7	142
GO:0006457	protein folding	1.73e-01	1.00e+00	2.408	1	7	143
GO:0010628	positive regulation of gene expression	1.76e-01	1.00e+00	2.378	1	5	146
GO:0008017	microtubule binding	1.77e-01	1.00e+00	2.368	1	6	147
GO:0005198	structural molecule activity	1.80e-01	1.00e+00	2.339	1	5	150
GO:0005769	early endosome	1.82e-01	1.00e+00	2.320	1	2	152
GO:0008543	fibroblast growth factor receptor signaling pathway	1.87e-01	1.00e+00	2.283	1	9	156
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.96e-01	1.00e+00	2.202	1	7	165
GO:0031965	nuclear membrane	2.00e-01	1.00e+00	2.176	1	3	168
GO:0006886	intracellular protein transport	2.03e-01	1.00e+00	2.150	1	5	171
GO:0005764	lysosome	2.04e-01	1.00e+00	2.142	1	2	172
GO:0032403	protein complex binding	2.16e-01	1.00e+00	2.052	1	10	183
GO:0005524	ATP binding	2.41e-01	1.00e+00	0.811	3	60	1298
GO:0005759	mitochondrial matrix	2.61e-01	1.00e+00	1.735	1	14	228
GO:0008380	RNA splicing	2.61e-01	1.00e+00	1.735	1	11	228
GO:0043025	neuronal cell body	2.78e-01	1.00e+00	1.632	1	9	245
GO:0005975	carbohydrate metabolic process	2.86e-01	1.00e+00	1.585	1	9	253
GO:0004842	ubiquitin-protein transferase activity	2.88e-01	1.00e+00	1.574	1	6	255
GO:0043065	positive regulation of apoptotic process	3.00e-01	1.00e+00	1.502	1	10	268
GO:0005743	mitochondrial inner membrane	3.08e-01	1.00e+00	1.454	1	8	277
GO:0019899	enzyme binding	3.08e-01	1.00e+00	1.454	1	12	277
GO:0007264	small GTPase mediated signal transduction	3.10e-01	1.00e+00	1.444	1	4	279
GO:0005856	cytoskeleton	3.21e-01	1.00e+00	1.383	1	12	291
GO:0006200	ATP catabolic process	3.22e-01	1.00e+00	1.378	1	15	292
GO:0016567	protein ubiquitination	3.25e-01	1.00e+00	1.364	1	5	295
GO:0007411	axon guidance	3.46e-01	1.00e+00	1.251	1	13	319
GO:0008283	cell proliferation	3.54e-01	1.00e+00	1.211	1	14	328
GO:0007268	synaptic transmission	3.58e-01	1.00e+00	1.193	1	6	332
GO:0005615	extracellular space	3.62e-01	1.00e+00	0.666	2	17	957
GO:0015031	protein transport	3.65e-01	1.00e+00	1.155	1	5	341
GO:0003723	RNA binding	3.66e-01	1.00e+00	1.150	1	20	342
GO:0005739	mitochondrion	3.82e-01	1.00e+00	0.605	2	28	998
GO:0007155	cell adhesion	3.89e-01	1.00e+00	1.041	1	6	369
GO:0046982	protein heterodimerization activity	3.98e-01	1.00e+00	0.998	1	13	380
GO:0009986	cell surface	4.16e-01	1.00e+00	0.917	1	11	402
GO:0055114	oxidation-reduction process	4.30e-01	1.00e+00	0.854	1	12	420
GO:0055085	transmembrane transport	4.41e-01	1.00e+00	0.803	1	10	435
GO:0005886	plasma membrane	4.50e-01	1.00e+00	0.234	4	45	2582
GO:0007596	blood coagulation	4.56e-01	1.00e+00	0.738	1	18	455
GO:0048471	perinuclear region of cytoplasm	4.90e-01	1.00e+00	0.597	1	13	502
GO:0042803	protein homodimerization activity	5.51e-01	1.00e+00	0.351	1	12	595
GO:0045087	innate immune response	5.52e-01	1.00e+00	0.349	1	24	596
GO:0005794	Golgi apparatus	5.60e-01	1.00e+00	0.315	1	15	610
GO:0005737	cytoplasm	5.79e-01	1.00e+00	0.011	5	110	3767
GO:0006355	regulation of transcription, DNA-templated	7.44e-01	1.00e+00	-0.393	1	18	997
GO:0008270	zinc ion binding	7.44e-01	1.00e+00	-0.393	1	12	997
GO:0016021	integral component of membrane	9.40e-01	1.00e+00	-1.385	1	27	1982

Wolf-ratios-Mammosphere-Adherent

int-snw-7879

Statistics

Genes (19)

Interactions (50)

Related GO terms (363)