int-snw-7124

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
wolf-screen-ratio-mammosphere-adherent	0.967	8.73e-17	1.20e-03	2.36e-02

wolf-screen-ratio-mammosphere-adherent-int-snw-7124 subnetwork

Genes (18)

Gene Symbol	Entrez Gene ID	Frequency	wolf-screen-ratio-mammosphere-adherent gene score	Best subnetwork score	Degree	wolf adherent-list Hits GI	wolf mammosphere no adherent-list Hits GI
[ TNF ]	7124	1	0.021	0.967	98	-	-
RBX1	9978	97	1.185	1.151	139	Yes	-
RPL8	6132	9	0.778	0.967	218	Yes	-
PSMB7	5695	48	0.982	1.052	57	Yes	-
PSMA1	5682	61	0.996	1.052	123	Yes	-
ATP6V1B2	526	44	0.881	1.076	278	-	-
RPSA	3921	156	1.327	1.151	152	Yes	-
RPA2	6118	98	1.250	1.151	69	Yes	-
CDC16	8881	25	0.950	1.020	80	Yes	-
EEF2	1938	27	0.890	1.043	301	Yes	-
PSMD3	5709	57	0.986	1.106	146	Yes	-
RPS11	6205	36	0.993	1.113	175	Yes	-
CLTC	1213	35	0.884	1.138	247	Yes	-
RPL14	9045	42	1.250	1.113	143	Yes	-
PSMB2	5690	18	0.877	1.026	117	Yes	-
ACTB	60	167	1.153	1.151	587	Yes	-
PSMD11	5717	121	1.095	1.106	183	Yes	-
HSPD1	3329	35	0.913	1.035	286	Yes	-

Interactions (37)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PSMD3	5709	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
ACTB	60	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
RPSA	3921	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
ACTB	60	ATP6V1B2	526	pp	--	int.I2D: BioGrid_Yeast
ATP6V1B2	526	RPSA	3921	pp	--	int.I2D: IntAct_Yeast
PSMB7	5695	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
ATP6V1B2	526	CDC16	8881	pp	--	int.I2D: IntAct_Yeast
PSMB7	5695	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast
ATP6V1B2	526	CLTC	1213	pp	--	int.I2D: IntAct_Yeast
ACTB	60	PSMA1	5682	pp	--	int.I2D: BioGrid_Yeast
HSPD1	3329	RPSA	3921	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RPS11	6205	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
PSMA1	5682	PSMB2	5690	pp	--	int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid
ACTB	60	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	TNF	7124	pp	--	int.I2D: IntAct_Rat
PSMA1	5682	PSMD3	5709	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
RPL8	6132	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, YeastMedium
RPSA	3921	PSMD11	5717	pp	--	int.I2D: IntAct_Yeast
PSMA1	5682	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ACTB	60	RPSA	3921	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct
PSMA1	5682	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB	60	CLTC	1213	pp	--	int.I2D: IntAct_Yeast
ACTB	60	RBX1	9978	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	RPL8	6132	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMB2	5690	pp	--	int.I2D: BioGrid_Yeast
ACTB	60	PSMB7	5695	pp	--	int.I2D: BioGrid_Yeast
PSMB2	5690	PSMB7	5695	pp	--	int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
ACTB	60	CDC16	8881	pp	--	int.I2D: YeastLow
PSMB2	5690	PSMD11	5717	pp	--	int.I2D: BioGrid_Yeast, YeastLow
RPL8	6132	TNF	7124	pp	--	int.I2D: IntAct_Rat
EEF2	1938	HSPD1	3329	pp	--	int.I2D: YeastLow, YeastMedium
ACTB	60	RPA2	6118	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
ACTB	60	EEF2	1938	pp	--	int.I2D: YeastLow, IntAct_Yeast
RPL8	6132	RPL14	9045	pp	--	int.I2D: BioGrid_Yeast
EEF2	1938	PSMD3	5709	pp	--	int.I2D: Krogan_NonCore
ACTB	60	HSPD1	3329	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct, YeastLow

Related GO terms (373)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0016071	mRNA metabolic process	1.85e-12	2.67e-08	5.015	9	31	223
GO:0016032	viral process	4.07e-12	5.87e-08	4.045	11	55	534
GO:0016070	RNA metabolic process	4.66e-12	6.72e-08	4.868	9	32	247
GO:0005829	cytosol	6.68e-11	9.64e-07	2.361	16	132	2496
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.18e-10	1.70e-06	6.209	6	22	65
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.86e-10	2.69e-06	6.102	6	22	70
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	2.62e-10	3.78e-06	6.022	6	22	74
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	3.92e-10	5.66e-06	5.927	6	23	79
GO:0010467	gene expression	1.35e-09	1.94e-05	3.582	10	59	669
GO:0006521	regulation of cellular amino acid metabolic process	3.38e-09	4.87e-05	6.324	5	17	50
GO:0000502	proteasome complex	7.26e-09	1.05e-04	6.110	5	17	58
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	1.20e-08	1.73e-04	5.968	5	19	64
GO:0000082	G1/S transition of mitotic cell cycle	1.84e-08	2.66e-04	5.012	6	32	149
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	2.19e-08	3.16e-04	5.798	5	20	72
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	2.70e-08	3.89e-04	5.739	5	20	75
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	7.59e-08	1.10e-03	5.445	5	21	92
GO:0006414	translational elongation	8.02e-08	1.16e-03	5.429	5	13	93
GO:0000209	protein polyubiquitination	2.43e-07	3.51e-03	5.110	5	20	116
GO:0000278	mitotic cell cycle	2.51e-07	3.62e-03	3.842	7	48	391
GO:0070062	extracellular vesicular exosome	2.72e-07	3.92e-03	2.118	13	104	2400
GO:0016020	membrane	7.61e-07	1.10e-02	2.390	11	90	1681
GO:0042981	regulation of apoptotic process	8.74e-07	1.26e-02	4.739	5	24	150
GO:0005839	proteasome core complex	1.32e-06	1.90e-02	7.061	3	8	18
GO:0004298	threonine-type endopeptidase activity	1.56e-06	2.25e-02	6.983	3	8	19
GO:0034641	cellular nitrogen compound metabolic process	1.67e-06	2.41e-02	4.550	5	20	171
GO:0005654	nucleoplasm	1.90e-06	2.75e-02	2.737	9	76	1082
GO:0019083	viral transcription	2.66e-06	3.84e-02	5.306	4	10	81
GO:0006415	translational termination	3.54e-06	5.11e-02	5.203	4	10	87
GO:0006412	translation	7.14e-06	1.03e-01	4.123	5	20	230
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	7.22e-06	1.04e-01	4.946	4	10	104
GO:0043066	negative regulation of apoptotic process	8.57e-06	1.24e-01	3.503	6	31	424
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.04e-05	1.50e-01	4.813	4	11	114
GO:0019058	viral life cycle	1.08e-05	1.55e-01	4.801	4	13	115
GO:0044267	cellular protein metabolic process	1.62e-05	2.33e-01	3.342	6	29	474
GO:0006413	translational initiation	1.80e-05	2.60e-01	4.613	4	17	131
GO:0003735	structural constituent of ribosome	2.15e-05	3.10e-01	4.548	4	10	137
GO:0006915	apoptotic process	3.95e-05	5.70e-01	3.115	6	33	555
GO:0005838	proteasome regulatory particle	9.64e-05	1.00e+00	7.061	2	7	12
GO:0044822	poly(A) RNA binding	1.72e-04	1.00e+00	2.409	7	49	1056
GO:0022624	proteasome accessory complex	1.98e-04	1.00e+00	6.559	2	8	17
GO:0005844	polysome	3.66e-04	1.00e+00	6.123	2	4	23
GO:0005515	protein binding	3.76e-04	1.00e+00	0.997	15	184	6024
GO:0019843	rRNA binding	5.07e-04	1.00e+00	5.891	2	3	27
GO:0033572	transferrin transport	6.27e-04	1.00e+00	5.739	2	5	30
GO:0032755	positive regulation of interleukin-6 production	9.04e-04	1.00e+00	5.476	2	2	36
GO:0005925	focal adhesion	9.41e-04	1.00e+00	3.130	4	19	366
GO:0032729	positive regulation of interferon-gamma production	1.06e-03	1.00e+00	5.361	2	2	39
GO:0022627	cytosolic small ribosomal subunit	1.06e-03	1.00e+00	5.361	2	4	39
GO:0002842	positive regulation of T cell mediated immune response to tumor cell	1.25e-03	1.00e+00	9.646	1	1	1
GO:0048291	isotype switching to IgG isotypes	1.25e-03	1.00e+00	9.646	1	1	1
GO:0002037	negative regulation of L-glutamate transport	1.25e-03	1.00e+00	9.646	1	1	1
GO:0061048	negative regulation of branching involved in lung morphogenesis	1.25e-03	1.00e+00	9.646	1	1	1
GO:0045994	positive regulation of translational initiation by iron	1.25e-03	1.00e+00	9.646	1	1	1
GO:0002368	B cell cytokine production	1.25e-03	1.00e+00	9.646	1	1	1
GO:0022625	cytosolic large ribosomal subunit	1.67e-03	1.00e+00	5.031	2	6	49
GO:0003725	double-stranded RNA binding	1.88e-03	1.00e+00	4.946	2	5	52
GO:0006407	rRNA export from nucleus	2.49e-03	1.00e+00	8.646	1	1	2
GO:1990268	response to gold nanoparticle	2.49e-03	1.00e+00	8.646	1	1	2
GO:0002439	chronic inflammatory response to antigenic stimulus	2.49e-03	1.00e+00	8.646	1	1	2
GO:0060557	positive regulation of vitamin D biosynthetic process	2.49e-03	1.00e+00	8.646	1	1	2
GO:0002876	positive regulation of chronic inflammatory response to antigenic stimulus	2.49e-03	1.00e+00	8.646	1	1	2
GO:0000461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	2.49e-03	1.00e+00	8.646	1	1	2
GO:0005055	laminin receptor activity	2.49e-03	1.00e+00	8.646	1	1	2
GO:0003697	single-stranded DNA binding	3.19e-03	1.00e+00	4.559	2	5	68
GO:0060559	positive regulation of calcidiol 1-monooxygenase activity	3.74e-03	1.00e+00	8.061	1	1	3
GO:0060693	regulation of branching involved in salivary gland morphogenesis	3.74e-03	1.00e+00	8.061	1	1	3
GO:0043243	positive regulation of protein complex disassembly	3.74e-03	1.00e+00	8.061	1	1	3
GO:0032800	receptor biosynthetic process	3.74e-03	1.00e+00	8.061	1	1	3
GO:1900126	negative regulation of hyaluronan biosynthetic process	3.74e-03	1.00e+00	8.061	1	2	3
GO:0006458	'de novo' protein folding	3.74e-03	1.00e+00	8.061	1	1	3
GO:0071677	positive regulation of mononuclear cell migration	3.74e-03	1.00e+00	8.061	1	1	3
GO:0030135	coated vesicle	3.74e-03	1.00e+00	8.061	1	1	3
GO:0071439	clathrin complex	3.74e-03	1.00e+00	8.061	1	2	3
GO:0032741	positive regulation of interleukin-18 production	3.74e-03	1.00e+00	8.061	1	1	3
GO:0030730	sequestering of triglyceride	3.74e-03	1.00e+00	8.061	1	1	3
GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	4.07e-03	1.00e+00	4.379	2	7	77
GO:0010693	negative regulation of alkaline phosphatase activity	4.98e-03	1.00e+00	7.646	1	1	4
GO:0000447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	4.98e-03	1.00e+00	7.646	1	1	4
GO:0030686	90S preribosome	4.98e-03	1.00e+00	7.646	1	1	4
GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	4.98e-03	1.00e+00	7.646	1	1	4
GO:0032051	clathrin light chain binding	4.98e-03	1.00e+00	7.646	1	1	4
GO:0051533	positive regulation of NFAT protein import into nucleus	4.98e-03	1.00e+00	7.646	1	1	4
GO:0019788	NEDD8 ligase activity	4.98e-03	1.00e+00	7.646	1	1	4
GO:0043242	negative regulation of protein complex disassembly	4.98e-03	1.00e+00	7.646	1	1	4
GO:0051222	positive regulation of protein transport	4.98e-03	1.00e+00	7.646	1	1	4
GO:0051798	positive regulation of hair follicle development	4.98e-03	1.00e+00	7.646	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	4.98e-03	1.00e+00	7.646	1	1	4
GO:1903077	negative regulation of protein localization to plasma membrane	4.98e-03	1.00e+00	7.646	1	1	4
GO:0043234	protein complex	5.50e-03	1.00e+00	3.027	3	18	295
GO:0042470	melanosome	5.64e-03	1.00e+00	4.138	2	9	91
GO:0001649	osteoblast differentiation	5.76e-03	1.00e+00	4.123	2	6	92
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	6.23e-03	1.00e+00	7.324	1	3	5
GO:0002740	negative regulation of cytokine secretion involved in immune response	6.23e-03	1.00e+00	7.324	1	1	5
GO:0031622	positive regulation of fever generation	6.23e-03	1.00e+00	7.324	1	2	5
GO:2000001	regulation of DNA damage checkpoint	6.23e-03	1.00e+00	7.324	1	1	5
GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin	6.23e-03	1.00e+00	7.324	1	1	5
GO:0031461	cullin-RING ubiquitin ligase complex	6.23e-03	1.00e+00	7.324	1	1	5
GO:0051023	regulation of immunoglobulin secretion	6.23e-03	1.00e+00	7.324	1	1	5
GO:0043248	proteasome assembly	6.23e-03	1.00e+00	7.324	1	1	5
GO:0046696	lipopolysaccharide receptor complex	6.23e-03	1.00e+00	7.324	1	1	5
GO:0030891	VCB complex	6.23e-03	1.00e+00	7.324	1	2	5
GO:0071803	positive regulation of podosome assembly	6.23e-03	1.00e+00	7.324	1	1	5
GO:0000730	DNA recombinase assembly	6.23e-03	1.00e+00	7.324	1	1	5
GO:0019901	protein kinase binding	6.72e-03	1.00e+00	2.923	3	21	317
GO:0003688	DNA replication origin binding	7.47e-03	1.00e+00	7.061	1	2	6
GO:0097527	necroptotic signaling pathway	7.47e-03	1.00e+00	7.061	1	1	6
GO:0030130	clathrin coat of trans-Golgi network vesicle	7.47e-03	1.00e+00	7.061	1	3	6
GO:0030118	clathrin coat	7.47e-03	1.00e+00	7.061	1	2	6
GO:0031466	Cul5-RING ubiquitin ligase complex	7.47e-03	1.00e+00	7.061	1	1	6
GO:0030957	Tat protein binding	7.47e-03	1.00e+00	7.061	1	3	6
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	7.47e-03	1.00e+00	7.061	1	1	6
GO:0006927	transformed cell apoptotic process	7.47e-03	1.00e+00	7.061	1	1	6
GO:2000010	positive regulation of protein localization to cell surface	7.47e-03	1.00e+00	7.061	1	2	6
GO:0003723	RNA binding	8.28e-03	1.00e+00	2.813	3	20	342
GO:0030529	ribonucleoprotein complex	8.43e-03	1.00e+00	3.839	2	8	112
GO:0005819	spindle	8.43e-03	1.00e+00	3.839	2	7	112
GO:0000028	ribosomal small subunit assembly	8.71e-03	1.00e+00	6.839	1	1	7
GO:0034116	positive regulation of heterotypic cell-cell adhesion	8.71e-03	1.00e+00	6.839	1	1	7
GO:0045760	positive regulation of action potential	8.71e-03	1.00e+00	6.839	1	1	7
GO:0010888	negative regulation of lipid storage	8.71e-03	1.00e+00	6.839	1	2	7
GO:0031462	Cul2-RING ubiquitin ligase complex	8.71e-03	1.00e+00	6.839	1	2	7
GO:0046325	negative regulation of glucose import	8.71e-03	1.00e+00	6.839	1	1	7
GO:0033180	proton-transporting V-type ATPase, V1 domain	8.71e-03	1.00e+00	6.839	1	2	7
GO:0045416	positive regulation of interleukin-8 biosynthetic process	8.71e-03	1.00e+00	6.839	1	1	7
GO:0030132	clathrin coat of coated pit	8.71e-03	1.00e+00	6.839	1	2	7
GO:0001775	cell activation	8.71e-03	1.00e+00	6.839	1	1	7
GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	8.71e-03	1.00e+00	6.839	1	1	7
GO:0060664	epithelial cell proliferation involved in salivary gland morphogenesis	8.71e-03	1.00e+00	6.839	1	1	7
GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	9.94e-03	1.00e+00	6.646	1	2	8
GO:0071316	cellular response to nicotine	9.94e-03	1.00e+00	6.646	1	1	8
GO:0070688	MLL5-L complex	9.94e-03	1.00e+00	6.646	1	1	8
GO:0045116	protein neddylation	9.94e-03	1.00e+00	6.646	1	2	8
GO:0019773	proteasome core complex, alpha-subunit complex	9.94e-03	1.00e+00	6.646	1	4	8
GO:0043068	positive regulation of programmed cell death	9.94e-03	1.00e+00	6.646	1	1	8
GO:0051604	protein maturation	9.94e-03	1.00e+00	6.646	1	1	8
GO:0008494	translation activator activity	1.12e-02	1.00e+00	6.476	1	1	9
GO:0000185	activation of MAPKKK activity	1.12e-02	1.00e+00	6.476	1	2	9
GO:0045080	positive regulation of chemokine biosynthetic process	1.12e-02	1.00e+00	6.476	1	1	9
GO:0010569	regulation of double-strand break repair via homologous recombination	1.24e-02	1.00e+00	6.324	1	1	10
GO:0043032	positive regulation of macrophage activation	1.24e-02	1.00e+00	6.324	1	1	10
GO:0043122	regulation of I-kappaB kinase/NF-kappaB signaling	1.36e-02	1.00e+00	6.187	1	1	11
GO:0032727	positive regulation of interferon-alpha production	1.36e-02	1.00e+00	6.187	1	1	11
GO:0031571	mitotic G1 DNA damage checkpoint	1.36e-02	1.00e+00	6.187	1	4	11
GO:0061024	membrane organization	1.38e-02	1.00e+00	3.466	2	7	145
GO:0010628	positive regulation of gene expression	1.40e-02	1.00e+00	3.456	2	5	146
GO:0044281	small molecule metabolic process	1.41e-02	1.00e+00	1.726	5	58	1211
GO:0050806	positive regulation of synaptic transmission	1.49e-02	1.00e+00	6.061	1	1	12
GO:0042273	ribosomal large subunit biogenesis	1.61e-02	1.00e+00	5.946	1	4	13
GO:0050995	negative regulation of lipid catabolic process	1.61e-02	1.00e+00	5.946	1	1	13
GO:0005662	DNA replication factor A complex	1.61e-02	1.00e+00	5.946	1	1	13
GO:0031334	positive regulation of protein complex assembly	1.61e-02	1.00e+00	5.946	1	2	13
GO:0030234	enzyme regulator activity	1.61e-02	1.00e+00	5.946	1	3	13
GO:0001530	lipopolysaccharide binding	1.61e-02	1.00e+00	5.946	1	3	13
GO:0001891	phagocytic cup	1.61e-02	1.00e+00	5.946	1	2	13
GO:0051131	chaperone-mediated protein complex assembly	1.61e-02	1.00e+00	5.946	1	1	13
GO:0035267	NuA4 histone acetyltransferase complex	1.73e-02	1.00e+00	5.839	1	4	14
GO:2000377	regulation of reactive oxygen species metabolic process	1.73e-02	1.00e+00	5.839	1	1	14
GO:0048566	embryonic digestive tract development	1.73e-02	1.00e+00	5.839	1	2	14
GO:0009651	response to salt stress	1.73e-02	1.00e+00	5.839	1	2	14
GO:0051044	positive regulation of membrane protein ectodomain proteolysis	1.73e-02	1.00e+00	5.839	1	1	14
GO:0050901	leukocyte tethering or rolling	1.86e-02	1.00e+00	5.739	1	1	15
GO:0042026	protein refolding	1.86e-02	1.00e+00	5.739	1	2	15
GO:0046034	ATP metabolic process	1.86e-02	1.00e+00	5.739	1	1	15
GO:0046961	proton-transporting ATPase activity, rotational mechanism	1.86e-02	1.00e+00	5.739	1	3	15
GO:0042176	regulation of protein catabolic process	1.98e-02	1.00e+00	5.646	1	3	16
GO:0032722	positive regulation of chemokine production	1.98e-02	1.00e+00	5.646	1	1	16
GO:0050998	nitric-oxide synthase binding	1.98e-02	1.00e+00	5.646	1	1	16
GO:0031625	ubiquitin protein ligase binding	2.04e-02	1.00e+00	3.170	2	14	178
GO:0010243	response to organonitrogen compound	2.10e-02	1.00e+00	5.559	1	3	17
GO:0001819	positive regulation of cytokine production	2.10e-02	1.00e+00	5.559	1	1	17
GO:0003746	translation elongation factor activity	2.10e-02	1.00e+00	5.559	1	3	17
GO:0003009	skeletal muscle contraction	2.10e-02	1.00e+00	5.559	1	1	17
GO:0050870	positive regulation of T cell activation	2.10e-02	1.00e+00	5.559	1	1	17
GO:0044130	negative regulation of growth of symbiont in host	2.10e-02	1.00e+00	5.559	1	1	17
GO:0035861	site of double-strand break	2.22e-02	1.00e+00	5.476	1	1	18
GO:0007088	regulation of mitosis	2.22e-02	1.00e+00	5.476	1	1	18
GO:0045672	positive regulation of osteoclast differentiation	2.22e-02	1.00e+00	5.476	1	1	18
GO:0042346	positive regulation of NF-kappaB import into nucleus	2.22e-02	1.00e+00	5.476	1	2	18
GO:0015078	hydrogen ion transmembrane transporter activity	2.35e-02	1.00e+00	5.398	1	3	19
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	2.35e-02	1.00e+00	5.398	1	1	19
GO:0048863	stem cell differentiation	2.35e-02	1.00e+00	5.398	1	1	19
GO:0032733	positive regulation of interleukin-10 production	2.35e-02	1.00e+00	5.398	1	1	19
GO:0005680	anaphase-promoting complex	2.47e-02	1.00e+00	5.324	1	4	20
GO:0032715	negative regulation of interleukin-6 production	2.47e-02	1.00e+00	5.324	1	1	20
GO:0006298	mismatch repair	2.47e-02	1.00e+00	5.324	1	3	20
GO:0042100	B cell proliferation	2.59e-02	1.00e+00	5.254	1	1	21
GO:0000718	nucleotide-excision repair, DNA damage removal	2.59e-02	1.00e+00	5.254	1	4	21
GO:0032201	telomere maintenance via semi-conservative replication	2.59e-02	1.00e+00	5.254	1	5	21
GO:0030316	osteoclast differentiation	2.71e-02	1.00e+00	5.187	1	1	22
GO:0050715	positive regulation of cytokine secretion	2.71e-02	1.00e+00	5.187	1	1	22
GO:0006297	nucleotide-excision repair, DNA gap filling	2.71e-02	1.00e+00	5.187	1	3	22
GO:0030863	cortical cytoskeleton	2.71e-02	1.00e+00	5.187	1	1	22
GO:0036464	cytoplasmic ribonucleoprotein granule	2.71e-02	1.00e+00	5.187	1	4	22
GO:0031463	Cul3-RING ubiquitin ligase complex	2.83e-02	1.00e+00	5.123	1	3	23
GO:0043236	laminin binding	2.83e-02	1.00e+00	5.123	1	1	23
GO:0006513	protein monoubiquitination	2.83e-02	1.00e+00	5.123	1	1	23
GO:0043044	ATP-dependent chromatin remodeling	2.83e-02	1.00e+00	5.123	1	4	23
GO:0000060	protein import into nucleus, translocation	2.95e-02	1.00e+00	5.061	1	5	24
GO:0000722	telomere maintenance via recombination	3.08e-02	1.00e+00	5.002	1	5	25
GO:0042113	B cell activation	3.08e-02	1.00e+00	5.002	1	2	25
GO:0032735	positive regulation of interleukin-12 production	3.08e-02	1.00e+00	5.002	1	1	25
GO:0070979	protein K11-linked ubiquitination	3.20e-02	1.00e+00	4.946	1	6	26
GO:0007067	mitotic nuclear division	3.20e-02	1.00e+00	2.820	2	14	227
GO:0015991	ATP hydrolysis coupled proton transport	3.20e-02	1.00e+00	4.946	1	4	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	3.20e-02	1.00e+00	4.946	1	3	26
GO:0043022	ribosome binding	3.32e-02	1.00e+00	4.891	1	3	27
GO:0009314	response to radiation	3.32e-02	1.00e+00	4.891	1	1	27
GO:0031492	nucleosomal DNA binding	3.32e-02	1.00e+00	4.891	1	4	27
GO:0033209	tumor necrosis factor-mediated signaling pathway	3.44e-02	1.00e+00	4.839	1	2	28
GO:0045840	positive regulation of mitosis	3.44e-02	1.00e+00	4.839	1	2	28
GO:0043507	positive regulation of JUN kinase activity	3.44e-02	1.00e+00	4.839	1	2	28
GO:0030669	clathrin-coated endocytic vesicle membrane	3.44e-02	1.00e+00	4.839	1	4	28
GO:0019894	kinesin binding	3.44e-02	1.00e+00	4.839	1	1	28
GO:0019005	SCF ubiquitin ligase complex	3.56e-02	1.00e+00	4.788	1	1	29
GO:0015992	proton transport	3.56e-02	1.00e+00	4.788	1	3	29
GO:0031663	lipopolysaccharide-mediated signaling pathway	3.56e-02	1.00e+00	4.788	1	2	29
GO:0006271	DNA strand elongation involved in DNA replication	3.68e-02	1.00e+00	4.739	1	7	30
GO:0005164	tumor necrosis factor receptor binding	3.68e-02	1.00e+00	4.739	1	2	30
GO:0014823	response to activity	3.80e-02	1.00e+00	4.692	1	1	31
GO:0031623	receptor internalization	3.80e-02	1.00e+00	4.692	1	2	31
GO:0007094	mitotic spindle assembly checkpoint	3.80e-02	1.00e+00	4.692	1	4	31
GO:0043491	protein kinase B signaling	3.92e-02	1.00e+00	4.646	1	2	32
GO:0051701	interaction with host	3.92e-02	1.00e+00	4.646	1	4	32
GO:0006281	DNA repair	4.13e-02	1.00e+00	2.618	2	18	261
GO:0032588	trans-Golgi network membrane	4.16e-02	1.00e+00	4.559	1	2	34
GO:0001895	retina homeostasis	4.16e-02	1.00e+00	4.559	1	1	34
GO:0008625	extrinsic apoptotic signaling pathway via death domain receptors	4.16e-02	1.00e+00	4.559	1	2	34
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	4.16e-02	1.00e+00	4.559	1	2	34
GO:0045071	negative regulation of viral genome replication	4.16e-02	1.00e+00	4.559	1	1	34
GO:0005876	spindle microtubule	4.16e-02	1.00e+00	4.559	1	2	34
GO:0045599	negative regulation of fat cell differentiation	4.28e-02	1.00e+00	4.517	1	2	35
GO:0045429	positive regulation of nitric oxide biosynthetic process	4.28e-02	1.00e+00	4.517	1	3	35
GO:0043065	positive regulation of apoptotic process	4.33e-02	1.00e+00	2.580	2	10	268
GO:0034332	adherens junction organization	4.40e-02	1.00e+00	4.476	1	1	36
GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	4.40e-02	1.00e+00	4.476	1	1	36
GO:0045668	negative regulation of osteoblast differentiation	4.40e-02	1.00e+00	4.476	1	1	36
GO:0090382	phagosome maturation	4.40e-02	1.00e+00	4.476	1	5	36
GO:0051084	'de novo' posttranslational protein folding	4.52e-02	1.00e+00	4.437	1	4	37
GO:0006284	base-excision repair	4.52e-02	1.00e+00	4.437	1	3	37
GO:0005730	nucleolus	4.58e-02	1.00e+00	1.288	5	69	1641
GO:0005902	microvillus	4.64e-02	1.00e+00	4.398	1	2	38
GO:0097191	extrinsic apoptotic signaling pathway	4.64e-02	1.00e+00	4.398	1	3	38
GO:0071407	cellular response to organic cyclic compound	4.64e-02	1.00e+00	4.398	1	2	38
GO:0070527	platelet aggregation	4.64e-02	1.00e+00	4.398	1	2	38
GO:0000781	chromosome, telomeric region	4.76e-02	1.00e+00	4.361	1	3	39
GO:0019722	calcium-mediated signaling	4.76e-02	1.00e+00	4.361	1	1	39
GO:0042110	T cell activation	5.12e-02	1.00e+00	4.254	1	3	42
GO:0030136	clathrin-coated vesicle	5.12e-02	1.00e+00	4.254	1	4	42
GO:0071230	cellular response to amino acid stimulus	5.12e-02	1.00e+00	4.254	1	3	42
GO:0006892	post-Golgi vesicle-mediated transport	5.24e-02	1.00e+00	4.220	1	3	43
GO:0014070	response to organic cyclic compound	5.24e-02	1.00e+00	4.220	1	4	43
GO:0021762	substantia nigra development	5.35e-02	1.00e+00	4.187	1	2	44
GO:0045727	positive regulation of translation	5.35e-02	1.00e+00	4.187	1	3	44
GO:0050830	defense response to Gram-positive bacterium	5.47e-02	1.00e+00	4.154	1	2	45
GO:0043525	positive regulation of neuron apoptotic process	5.59e-02	1.00e+00	4.123	1	2	46
GO:0006283	transcription-coupled nucleotide-excision repair	5.59e-02	1.00e+00	4.123	1	7	46
GO:0043406	positive regulation of MAP kinase activity	5.59e-02	1.00e+00	4.123	1	4	46
GO:0006959	humoral immune response	5.71e-02	1.00e+00	4.092	1	1	47
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	5.95e-02	1.00e+00	4.031	1	5	49
GO:0048661	positive regulation of smooth muscle cell proliferation	5.95e-02	1.00e+00	4.031	1	4	49
GO:0007254	JNK cascade	5.95e-02	1.00e+00	4.031	1	3	49
GO:0003684	damaged DNA binding	5.95e-02	1.00e+00	4.031	1	7	49
GO:0006986	response to unfolded protein	6.06e-02	1.00e+00	4.002	1	2	50
GO:0005905	coated pit	6.06e-02	1.00e+00	4.002	1	3	50
GO:0005813	centrosome	6.14e-02	1.00e+00	2.297	2	14	326
GO:0006879	cellular iron ion homeostasis	6.18e-02	1.00e+00	3.974	1	4	51
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	6.42e-02	1.00e+00	3.918	1	5	53
GO:0045216	cell-cell junction organization	6.53e-02	1.00e+00	3.891	1	2	54
GO:0002244	hematopoietic progenitor cell differentiation	6.53e-02	1.00e+00	3.891	1	1	54
GO:0002039	p53 binding	6.65e-02	1.00e+00	3.865	1	7	55
GO:0000724	double-strand break repair via homologous recombination	6.65e-02	1.00e+00	3.865	1	3	55
GO:0000723	telomere maintenance	6.77e-02	1.00e+00	3.839	1	6	56
GO:0012505	endomembrane system	6.77e-02	1.00e+00	3.839	1	2	56
GO:0005840	ribosome	7.00e-02	1.00e+00	3.788	1	1	58
GO:0033138	positive regulation of peptidyl-serine phosphorylation	7.12e-02	1.00e+00	3.764	1	2	59
GO:0051087	chaperone binding	7.12e-02	1.00e+00	3.764	1	6	59
GO:0006302	double-strand break repair	7.47e-02	1.00e+00	3.692	1	4	62
GO:0019903	protein phosphatase binding	7.47e-02	1.00e+00	3.692	1	4	62
GO:0051384	response to glucocorticoid	7.47e-02	1.00e+00	3.692	1	2	62
GO:0030141	secretory granule	7.47e-02	1.00e+00	3.692	1	2	62
GO:0006289	nucleotide-excision repair	8.16e-02	1.00e+00	3.559	1	11	68
GO:0034329	cell junction assembly	8.16e-02	1.00e+00	3.559	1	1	68
GO:0055037	recycling endosome	8.39e-02	1.00e+00	3.517	1	2	70
GO:0051897	positive regulation of protein kinase B signaling	8.39e-02	1.00e+00	3.517	1	1	70
GO:0000165	MAPK cascade	8.62e-02	1.00e+00	3.476	1	2	72
GO:0009986	cell surface	8.84e-02	1.00e+00	1.995	2	11	402
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	8.85e-02	1.00e+00	3.437	1	6	74
GO:0002020	protease binding	8.85e-02	1.00e+00	3.437	1	4	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	8.96e-02	1.00e+00	3.417	1	2	75
GO:0010629	negative regulation of gene expression	9.19e-02	1.00e+00	3.379	1	1	77
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	9.53e-02	1.00e+00	3.324	1	3	80
GO:0001726	ruffle	9.53e-02	1.00e+00	3.324	1	4	80
GO:0050796	regulation of insulin secretion	9.65e-02	1.00e+00	3.306	1	4	81
GO:0006898	receptor-mediated endocytosis	9.99e-02	1.00e+00	3.254	1	3	84
GO:0047485	protein N-terminus binding	1.02e-01	1.00e+00	3.220	1	5	86
GO:0009887	organ morphogenesis	1.02e-01	1.00e+00	3.220	1	2	86
GO:0050821	protein stabilization	1.04e-01	1.00e+00	3.187	1	2	88
GO:0016605	PML body	1.04e-01	1.00e+00	3.187	1	3	88
GO:0000187	activation of MAPK activity	1.07e-01	1.00e+00	3.154	1	5	90
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.07e-01	1.00e+00	3.154	1	7	90
GO:0006928	cellular component movement	1.08e-01	1.00e+00	3.138	1	7	91
GO:0005200	structural constituent of cytoskeleton	1.08e-01	1.00e+00	3.138	1	8	91
GO:0071456	cellular response to hypoxia	1.09e-01	1.00e+00	3.123	1	6	92
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	1.09e-01	1.00e+00	3.123	1	5	92
GO:0051082	unfolded protein binding	1.10e-01	1.00e+00	3.107	1	5	93
GO:0006364	rRNA processing	1.11e-01	1.00e+00	3.092	1	6	94
GO:0005615	extracellular space	1.13e-01	1.00e+00	1.329	3	17	957
GO:0001934	positive regulation of protein phosphorylation	1.22e-01	1.00e+00	2.946	1	6	104
GO:0014069	postsynaptic density	1.23e-01	1.00e+00	2.932	1	3	105
GO:0070374	positive regulation of ERK1 and ERK2 cascade	1.24e-01	1.00e+00	2.918	1	2	106
GO:0015630	microtubule cytoskeleton	1.29e-01	1.00e+00	2.865	1	4	110
GO:0072562	blood microparticle	1.30e-01	1.00e+00	2.852	1	3	111
GO:0097190	apoptotic signaling pathway	1.32e-01	1.00e+00	2.826	1	6	113
GO:0006006	glucose metabolic process	1.38e-01	1.00e+00	2.764	1	7	118
GO:0006325	chromatin organization	1.38e-01	1.00e+00	2.764	1	5	118
GO:0007219	Notch signaling pathway	1.40e-01	1.00e+00	2.739	1	5	120
GO:0006260	DNA replication	1.41e-01	1.00e+00	2.727	1	9	121
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.44e-01	1.00e+00	2.692	1	4	124
GO:0009615	response to virus	1.46e-01	1.00e+00	2.669	1	5	126
GO:0006511	ubiquitin-dependent protein catabolic process	1.46e-01	1.00e+00	2.669	1	5	126
GO:0000790	nuclear chromatin	1.49e-01	1.00e+00	2.635	1	9	129
GO:0031982	vesicle	1.52e-01	1.00e+00	2.613	1	9	131
GO:0005125	cytokine activity	1.59e-01	1.00e+00	2.538	1	1	138
GO:0016887	ATPase activity	1.61e-01	1.00e+00	2.517	1	7	140
GO:0008286	insulin receptor signaling pathway	1.63e-01	1.00e+00	2.496	1	7	142
GO:0006457	protein folding	1.64e-01	1.00e+00	2.486	1	7	143
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	1.66e-01	1.00e+00	2.466	1	4	145
GO:0001666	response to hypoxia	1.71e-01	1.00e+00	2.427	1	5	149
GO:0005198	structural molecule activity	1.72e-01	1.00e+00	2.417	1	5	150
GO:0005769	early endosome	1.74e-01	1.00e+00	2.398	1	2	152
GO:0045121	membrane raft	1.78e-01	1.00e+00	2.361	1	8	156
GO:0005634	nucleus	1.78e-01	1.00e+00	0.492	8	136	4559
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.87e-01	1.00e+00	2.280	1	7	165
GO:0030424	axon	1.88e-01	1.00e+00	2.271	1	4	166
GO:0044212	transcription regulatory region DNA binding	1.90e-01	1.00e+00	2.254	1	6	168
GO:0006886	intracellular protein transport	1.93e-01	1.00e+00	2.228	1	5	171
GO:0009897	external side of plasma membrane	1.99e-01	1.00e+00	2.179	1	3	177
GO:0032403	protein complex binding	2.05e-01	1.00e+00	2.130	1	10	183
GO:0005886	plasma membrane	2.08e-01	1.00e+00	0.634	5	45	2582
GO:0005524	ATP binding	2.17e-01	1.00e+00	0.889	3	60	1298
GO:0003924	GTPase activity	2.19e-01	1.00e+00	2.024	1	12	197
GO:0005765	lysosomal membrane	2.25e-01	1.00e+00	1.981	1	5	203
GO:0006184	GTP catabolic process	2.36e-01	1.00e+00	1.905	1	12	214
GO:0005759	mitochondrial matrix	2.49e-01	1.00e+00	1.813	1	14	228
GO:0004842	ubiquitin-protein transferase activity	2.75e-01	1.00e+00	1.652	1	6	255
GO:0005743	mitochondrial inner membrane	2.95e-01	1.00e+00	1.532	1	8	277
GO:0006954	inflammatory response	2.95e-01	1.00e+00	1.532	1	7	277
GO:0019899	enzyme binding	2.95e-01	1.00e+00	1.532	1	12	277
GO:0030198	extracellular matrix organization	3.00e-01	1.00e+00	1.502	1	4	283
GO:0042493	response to drug	3.01e-01	1.00e+00	1.496	1	13	284
GO:0005856	cytoskeleton	3.07e-01	1.00e+00	1.461	1	12	291
GO:0006200	ATP catabolic process	3.08e-01	1.00e+00	1.456	1	15	292
GO:0016567	protein ubiquitination	3.11e-01	1.00e+00	1.442	1	5	295
GO:0005737	cytoplasm	3.22e-01	1.00e+00	0.352	6	110	3767
GO:0005525	GTP binding	3.24e-01	1.00e+00	1.370	1	12	310
GO:0043231	intracellular membrane-bounded organelle	3.31e-01	1.00e+00	1.333	1	9	318
GO:0007411	axon guidance	3.32e-01	1.00e+00	1.329	1	13	319
GO:0008283	cell proliferation	3.39e-01	1.00e+00	1.289	1	14	328
GO:0008285	negative regulation of cell proliferation	3.60e-01	1.00e+00	1.183	1	11	353
GO:0007155	cell adhesion	3.73e-01	1.00e+00	1.119	1	6	369
GO:0045892	negative regulation of transcription, DNA-templated	4.07e-01	1.00e+00	0.956	1	15	413
GO:0055085	transmembrane transport	4.24e-01	1.00e+00	0.881	1	10	435
GO:0007596	blood coagulation	4.39e-01	1.00e+00	0.816	1	18	455
GO:0045893	positive regulation of transcription, DNA-templated	4.55e-01	1.00e+00	0.745	1	13	478
GO:0042802	identical protein binding	4.59e-01	1.00e+00	0.727	1	20	484
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.16e-01	1.00e+00	0.491	1	16	570
GO:0045087	innate immune response	5.32e-01	1.00e+00	0.427	1	24	596
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	6.37e-01	1.00e+00	0.022	1	19	789
GO:0005887	integral component of plasma membrane	6.82e-01	1.00e+00	-0.148	1	6	888
GO:0005576	extracellular region	7.04e-01	1.00e+00	-0.233	1	4	942
GO:0008270	zinc ion binding	7.25e-01	1.00e+00	-0.315	1	12	997
GO:0005739	mitochondrion	7.25e-01	1.00e+00	-0.317	1	28	998
GO:0016021	integral component of membrane	9.30e-01	1.00e+00	-1.307	1	27	1982

Wolf-ratios-Mammosphere-Adherent

int-snw-7124

Statistics

Genes (18)

Interactions (37)

Related GO terms (373)