TNF

Genes (1)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
TNF 7124 10.0210.96798--

Gene info in the NCBI database: TNF

Subnetworks (1)

Subnetwork ID wolf-screen-ratio-mammosphere-adherent score Size Highlighted genes
int-snw-7124 0.967 18 16

Related GO terms (130)

Accession number Name Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005515protein binding1846024
GO:0002740negative regulation of cytokine secretion involved in immune response15
GO:0002439chronic inflammatory response to antigenic stimulus12
GO:0045892negative regulation of transcription, DNA-templated15413
GO:0000187activation of MAPK activity590
GO:0071803positive regulation of podosome assembly15
GO:0001934positive regulation of protein phosphorylation6104
GO:0003009skeletal muscle contraction117
GO:0043122regulation of I-kappaB kinase/NF-kappaB signaling111
GO:0071316cellular response to nicotine18
GO:0051384response to glucocorticoid262
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling4145
GO:0051092positive regulation of NF-kappaB transcription factor activity4124
GO:0031663lipopolysaccharide-mediated signaling pathway229
GO:0060559positive regulation of calcidiol 1-monooxygenase activity13
GO:0005886plasma membrane452582
GO:0000060protein import into nucleus, translocation524
GO:0048566embryonic digestive tract development214
GO:0045760positive regulation of action potential17
GO:0045071negative regulation of viral genome replication134
GO:0043406positive regulation of MAP kinase activity446
GO:0042493response to drug13284
GO:0010888negative regulation of lipid storage27
GO:0048661positive regulation of smooth muscle cell proliferation449
GO:0045840positive regulation of mitosis228
GO:0045080positive regulation of chemokine biosynthetic process19
GO:0001775cell activation17
GO:0044212transcription regulatory region DNA binding6168
GO:0060664epithelial cell proliferation involved in salivary gland morphogenesis17
GO:0010628positive regulation of gene expression5146
GO:0050966detection of mechanical stimulus involved in sensory perception of pain17
GO:0050901leukocyte tethering or rolling115
GO:0051798positive regulation of hair follicle development14
GO:0006954inflammatory response7277
GO:0005615extracellular space17957
GO:0009314response to radiation127
GO:0033138positive regulation of peptidyl-serine phosphorylation259
GO:0031622positive regulation of fever generation25
GO:1990268response to gold nanoparticle12
GO:0009651response to salt stress214
GO:0030316osteoclast differentiation122
GO:2000377regulation of reactive oxygen species metabolic process114
GO:0051222positive regulation of protein transport14
GO:0032741positive regulation of interleukin-18 production13
GO:0060557positive regulation of vitamin D biosynthetic process12
GO:0051897positive regulation of protein kinase B signaling170
GO:0050715positive regulation of cytokine secretion122
GO:0030198extracellular matrix organization4283
GO:0032722positive regulation of chemokine production116
GO:0051023regulation of immunoglobulin secretion15
GO:0043243positive regulation of protein complex disassembly13
GO:0006927transformed cell apoptotic process16
GO:0005164tumor necrosis factor receptor binding230
GO:0050806positive regulation of synaptic transmission112
GO:0050796regulation of insulin secretion481
GO:0032715negative regulation of interleukin-6 production120
GO:0071230cellular response to amino acid stimulus342
GO:0019722calcium-mediated signaling139
GO:0002020protease binding474
GO:0032800receptor biosynthetic process13
GO:0071407cellular response to organic cyclic compound238
GO:0001666response to hypoxia5149
GO:0060693regulation of branching involved in salivary gland morphogenesis13
GO:0000185activation of MAPKKK activity29
GO:2001240negative regulation of extrinsic apoptotic signaling pathway in absence of ligand234
GO:0006006glucose metabolic process7118
GO:0014823response to activity131
GO:0042802identical protein binding20484
GO:0008625extrinsic apoptotic signaling pathway via death domain receptors234
GO:0009615response to virus5126
GO:0051044positive regulation of membrane protein ectodomain proteolysis114
GO:0005576extracellular region4942
GO:0045672positive regulation of osteoclast differentiation118
GO:0043280positive regulation of cysteine-type endopeptidase activity involved in apoptotic process136
GO:0045429positive regulation of nitric oxide biosynthetic process335
GO:0043242negative regulation of protein complex disassembly14
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity592
GO:0070374positive regulation of ERK1 and ERK2 cascade2106
GO:0043491protein kinase B signaling232
GO:0009986cell surface11402
GO:0045893positive regulation of transcription, DNA-templated13478
GO:0051533positive regulation of NFAT protein import into nucleus14
GO:0008285negative regulation of cell proliferation11353
GO:0034116positive regulation of heterotypic cell-cell adhesion17
GO:0097190apoptotic signaling pathway6113
GO:0031334positive regulation of protein complex assembly213
GO:0001891phagocytic cup213
GO:0043507positive regulation of JUN kinase activity228
GO:0010629negative regulation of gene expression177
GO:0097527necroptotic signaling pathway16
GO:0000165MAPK cascade272
GO:0045121membrane raft8156
GO:0045994positive regulation of translational initiation by iron11
GO:0045599negative regulation of fat cell differentiation235
GO:0033209tumor necrosis factor-mediated signaling pathway228
GO:0045944positive regulation of transcription from RNA polymerase II promoter19789
GO:0006915apoptotic process33555
GO:0030730sequestering of triglyceride13
GO:2000343positive regulation of chemokine (C-X-C motif) ligand 2 production14
GO:0005125cytokine activity1138
GO:0071677positive regulation of mononuclear cell migration13
GO:0043068positive regulation of programmed cell death18
GO:0050995negative regulation of lipid catabolic process113
GO:0050830defense response to Gram-positive bacterium245
GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage549
GO:0005887integral component of plasma membrane6888
GO:0055037recycling endosome270
GO:0044130negative regulation of growth of symbiont in host117
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process777
GO:0032755positive regulation of interleukin-6 production236
GO:0009887organ morphogenesis286
GO:0007254JNK cascade349
GO:0002037negative regulation of L-glutamate transport11
GO:0006959humoral immune response147
GO:0097191extrinsic apoptotic signaling pathway338
GO:0009897external side of plasma membrane3177
GO:0043065positive regulation of apoptotic process10268
GO:0043525positive regulation of neuron apoptotic process246
GO:0001819positive regulation of cytokine production117
GO:0045668negative regulation of osteoblast differentiation136
GO:0002876positive regulation of chronic inflammatory response to antigenic stimulus12
GO:0042346positive regulation of NF-kappaB import into nucleus218
GO:0010693negative regulation of alkaline phosphatase activity14
GO:0000122negative regulation of transcription from RNA polymerase II promoter16570
GO:0046325negative regulation of glucose import17
GO:0032729positive regulation of interferon-gamma production239
GO:0045416positive regulation of interleukin-8 biosynthetic process17
GO:2000010positive regulation of protein localization to cell surface26
GO:0002925positive regulation of humoral immune response mediated by circulating immunoglobulin15
GO:0061048negative regulation of branching involved in lung morphogenesis11