Dataset | Score | p-value 1 | p-value 2 | p-value 3 |
---|---|---|---|---|
wolf-screen-ratio-mammosphere-adherent | 0.958 | 2.06e-16 | 1.49e-03 | 2.77e-02 |
Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI |
---|---|---|---|---|---|---|---|
RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - |
ACACB | 32 | 5 | 0.656 | 1.002 | 184 | Yes | - |
ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - |
RUVBL1 | 8607 | 17 | 0.720 | 1.013 | 343 | Yes | - |
RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - |
PSMA2 | 5683 | 60 | 1.093 | 1.106 | 89 | Yes | - |
PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - |
PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - |
PSMD7 | 5713 | 5 | 0.640 | 0.958 | 133 | Yes | - |
PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - |
PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - |
ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - |
[ ARPC4 ] | 10093 | 1 | -0.085 | 0.958 | 54 | - | - |
RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - |
PGD | 5226 | 75 | 1.201 | 1.106 | 138 | Yes | - |
Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources |
---|---|---|---|---|---|---|
ACO2 | 50 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
ACO2 | 50 | PSMD7 | 5713 | pp | -- | int.I2D: YeastLow |
PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG |
PSMA2 | 5683 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA2 | 5683 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast |
PGD | 5226 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
PSMD7 | 5713 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
PSMD7 | 5713 | ARPC4 | 10093 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
PGD | 5226 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
PSMD7 | 5713 | PSMD11 | 5717 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastHigh, BioGrid, IntAct |
PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
ACACB | 32 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow |
PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium, IntAct_Yeast, MINT_Yeast |
RUVBL1 | 8607 | ARPC4 | 10093 | pp | -- | int.I2D: YeastLow |
PSMB7 | 5695 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD7 | 5713 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast |
ACACB | 32 | ARPC4 | 10093 | pp | -- | int.I2D: IntAct_Yeast |
PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium |
PSMD7 | 5713 | RBX1 | 9978 | pp | -- | int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast |
ACACB | 32 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast |
PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct |
PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast |
ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast |
ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast |
PSMA1 | 5682 | PSMA2 | 5683 | pp | -- | int.Intact: MI:0915(physical association), MI:0914(association); int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh; int.HPRD: yeast 2-hybrid |
PSMD3 | 5709 | PSMD7 | 5713 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct |
ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow |
ACTB | 60 | RUVBL1 | 8607 | pp | -- | int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast |
PSMD11 | 5717 | RUVBL1 | 8607 | pp | -- | int.I2D: YeastLow |
ACACB | 32 | RPSA | 3921 | pp | -- | int.I2D: IntAct_Yeast, YeastMedium |
ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct |
ACTB | 60 | ARPC4 | 10093 | pp | -- | int.I2D: BioGrid_Yeast |
ACO2 | 50 | PGD | 5226 | pp | -- | int.I2D: YeastLow |
PSMA2 | 5683 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow |
Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes |
---|---|---|---|---|---|---|---|
GO:0006521 | regulation of cellular amino acid metabolic process | 6.22e-12 | 8.97e-08 | 6.850 | 6 | 17 | 50 |
GO:0000502 | proteasome complex | 1.58e-11 | 2.28e-07 | 6.636 | 6 | 17 | 58 |
GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 2.91e-11 | 4.20e-07 | 6.494 | 6 | 19 | 64 |
GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.21e-11 | 4.63e-07 | 6.472 | 6 | 22 | 65 |
GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 5.08e-11 | 7.32e-07 | 6.365 | 6 | 22 | 70 |
GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 6.04e-11 | 8.72e-07 | 6.324 | 6 | 20 | 72 |
GO:0000082 | G1/S transition of mitotic cell cycle | 6.55e-11 | 9.44e-07 | 5.497 | 7 | 32 | 149 |
GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 7.16e-11 | 1.03e-06 | 6.285 | 6 | 22 | 74 |
GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 7.78e-11 | 1.12e-06 | 6.265 | 6 | 20 | 75 |
GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.07e-10 | 1.54e-06 | 6.190 | 6 | 23 | 79 |
GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 2.73e-10 | 3.94e-06 | 5.971 | 6 | 21 | 92 |
GO:0016071 | mRNA metabolic process | 1.11e-09 | 1.61e-05 | 4.916 | 7 | 31 | 223 |
GO:0000209 | protein polyubiquitination | 1.12e-09 | 1.62e-05 | 5.636 | 6 | 20 | 116 |
GO:0016070 | RNA metabolic process | 2.27e-09 | 3.28e-05 | 4.768 | 7 | 32 | 247 |
GO:0042981 | regulation of apoptotic process | 5.30e-09 | 7.65e-05 | 5.265 | 6 | 24 | 150 |
GO:0005654 | nucleoplasm | 1.15e-08 | 1.66e-04 | 3.152 | 10 | 76 | 1082 |
GO:0034641 | cellular nitrogen compound metabolic process | 1.17e-08 | 1.68e-04 | 5.076 | 6 | 20 | 171 |
GO:0016032 | viral process | 1.72e-08 | 2.47e-04 | 3.848 | 8 | 55 | 534 |
GO:0000278 | mitotic cell cycle | 5.44e-08 | 7.85e-04 | 4.106 | 7 | 48 | 391 |
GO:0005829 | cytosol | 1.91e-07 | 2.76e-03 | 2.209 | 12 | 132 | 2496 |
GO:0005838 | proteasome regulatory particle | 1.99e-07 | 2.87e-03 | 7.909 | 3 | 7 | 12 |
GO:0044281 | small molecule metabolic process | 6.33e-07 | 9.13e-03 | 2.837 | 9 | 58 | 1211 |
GO:0005839 | proteasome core complex | 7.36e-07 | 1.06e-02 | 7.324 | 3 | 8 | 18 |
GO:0004298 | threonine-type endopeptidase activity | 8.73e-07 | 1.26e-02 | 7.246 | 3 | 8 | 19 |
GO:0070062 | extracellular vesicular exosome | 1.88e-06 | 2.71e-02 | 2.140 | 11 | 104 | 2400 |
GO:0010467 | gene expression | 2.08e-06 | 3.00e-02 | 3.331 | 7 | 59 | 669 |
GO:0043066 | negative regulation of apoptotic process | 2.49e-06 | 3.59e-02 | 3.766 | 6 | 31 | 424 |
GO:0006915 | apoptotic process | 1.18e-05 | 1.70e-01 | 3.378 | 6 | 33 | 555 |
GO:0019773 | proteasome core complex, alpha-subunit complex | 2.82e-05 | 4.06e-01 | 7.909 | 2 | 4 | 8 |
GO:0035267 | NuA4 histone acetyltransferase complex | 9.12e-05 | 1.00e+00 | 7.102 | 2 | 4 | 14 |
GO:0022624 | proteasome accessory complex | 1.36e-04 | 1.00e+00 | 6.822 | 2 | 8 | 17 |
GO:0005634 | nucleus | 1.60e-04 | 1.00e+00 | 1.340 | 12 | 136 | 4559 |
GO:0019521 | D-gluconate metabolic process | 1.04e-03 | 1.00e+00 | 9.909 | 1 | 1 | 1 |
GO:2001295 | malonyl-CoA biosynthetic process | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0051538 | 3 iron, 4 sulfur cluster binding | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0003989 | acetyl-CoA carboxylase activity | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0019322 | pentose biosynthetic process | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 2 | 2 |
GO:0003994 | aconitate hydratase activity | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0005055 | laminin receptor activity | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0006407 | rRNA export from nucleus | 2.08e-03 | 1.00e+00 | 8.909 | 1 | 1 | 2 |
GO:0006281 | DNA repair | 2.27e-03 | 1.00e+00 | 3.466 | 3 | 18 | 261 |
GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 2.61e-03 | 1.00e+00 | 4.700 | 2 | 6 | 74 |
GO:0005515 | protein binding | 2.98e-03 | 1.00e+00 | 0.938 | 12 | 184 | 6024 |
GO:0006084 | acetyl-CoA metabolic process | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0009051 | pentose-phosphate shunt, oxidative branch | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 2 | 3 |
GO:0045010 | actin nucleation | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 3.12e-03 | 1.00e+00 | 8.324 | 1 | 1 | 3 |
GO:0005200 | structural constituent of cytoskeleton | 3.92e-03 | 1.00e+00 | 4.401 | 2 | 8 | 91 |
GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0030686 | 90S preribosome | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0031467 | Cul7-RING ubiquitin ligase complex | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0019788 | NEDD8 ligase activity | 4.15e-03 | 1.00e+00 | 7.909 | 1 | 1 | 4 |
GO:0005730 | nucleolus | 4.33e-03 | 1.00e+00 | 1.814 | 6 | 69 | 1641 |
GO:0016020 | membrane | 4.89e-03 | 1.00e+00 | 1.779 | 6 | 90 | 1681 |
GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 3 | 5 |
GO:0031461 | cullin-RING ubiquitin ligase complex | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0043248 | proteasome assembly | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0006102 | isocitrate metabolic process | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0030891 | VCB complex | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 2 | 5 |
GO:0000730 | DNA recombinase assembly | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0004075 | biotin carboxylase activity | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:2000001 | regulation of DNA damage checkpoint | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0009374 | biotin binding | 5.19e-03 | 1.00e+00 | 7.587 | 1 | 1 | 5 |
GO:0030529 | ribonucleoprotein complex | 5.87e-03 | 1.00e+00 | 4.102 | 2 | 8 | 112 |
GO:0030957 | Tat protein binding | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 3 | 6 |
GO:0006101 | citrate metabolic process | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
GO:0031466 | Cul5-RING ubiquitin ligase complex | 6.22e-03 | 1.00e+00 | 7.324 | 1 | 1 | 6 |
GO:0006325 | chromatin organization | 6.50e-03 | 1.00e+00 | 4.027 | 2 | 5 | 118 |
GO:0000028 | ribosomal small subunit assembly | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
GO:0005885 | Arp2/3 protein complex | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 1 | 7 |
GO:0031462 | Cul2-RING ubiquitin ligase complex | 7.26e-03 | 1.00e+00 | 7.102 | 1 | 2 | 7 |
GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 2 | 8 |
GO:0006853 | carnitine shuttle | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
GO:0031325 | positive regulation of cellular metabolic process | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
GO:0070688 | MLL5-L complex | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 1 | 8 |
GO:0000812 | Swr1 complex | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 3 | 8 |
GO:0045116 | protein neddylation | 8.29e-03 | 1.00e+00 | 6.909 | 1 | 2 | 8 |
GO:0006768 | biotin metabolic process | 9.32e-03 | 1.00e+00 | 6.739 | 1 | 1 | 9 |
GO:0006098 | pentose-phosphate shunt | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 4 | 10 |
GO:0010569 | regulation of double-strand break repair via homologous recombination | 1.04e-02 | 1.00e+00 | 6.587 | 1 | 1 | 10 |
GO:0034314 | Arp2/3 complex-mediated actin nucleation | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 1 | 11 |
GO:0031571 | mitotic G1 DNA damage checkpoint | 1.14e-02 | 1.00e+00 | 6.450 | 1 | 4 | 11 |
GO:0043968 | histone H2A acetylation | 1.24e-02 | 1.00e+00 | 6.324 | 1 | 3 | 12 |
GO:0005662 | DNA replication factor A complex | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 1 | 13 |
GO:0030234 | enzyme regulator activity | 1.34e-02 | 1.00e+00 | 6.209 | 1 | 3 | 13 |
GO:0031625 | ubiquitin protein ligase binding | 1.43e-02 | 1.00e+00 | 3.433 | 2 | 14 | 178 |
GO:0031011 | Ino80 complex | 1.45e-02 | 1.00e+00 | 6.102 | 1 | 3 | 14 |
GO:0050998 | nitric-oxide synthase binding | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 1 | 16 |
GO:0042176 | regulation of protein catabolic process | 1.65e-02 | 1.00e+00 | 5.909 | 1 | 3 | 16 |
GO:0003678 | DNA helicase activity | 1.75e-02 | 1.00e+00 | 5.822 | 1 | 3 | 17 |
GO:0035861 | site of double-strand break | 1.86e-02 | 1.00e+00 | 5.739 | 1 | 1 | 18 |
GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.96e-02 | 1.00e+00 | 5.661 | 1 | 1 | 19 |
GO:0048863 | stem cell differentiation | 1.96e-02 | 1.00e+00 | 5.661 | 1 | 1 | 19 |
GO:0006298 | mismatch repair | 2.06e-02 | 1.00e+00 | 5.587 | 1 | 3 | 20 |
GO:0030041 | actin filament polymerization | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 3 | 21 |
GO:0032201 | telomere maintenance via semi-conservative replication | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 5 | 21 |
GO:0000718 | nucleotide-excision repair, DNA damage removal | 2.16e-02 | 1.00e+00 | 5.517 | 1 | 4 | 21 |
GO:0006297 | nucleotide-excision repair, DNA gap filling | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 3 | 22 |
GO:0030863 | cortical cytoskeleton | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 1 | 22 |
GO:0036464 | cytoplasmic ribonucleoprotein granule | 2.26e-02 | 1.00e+00 | 5.450 | 1 | 4 | 22 |
GO:0043044 | ATP-dependent chromatin remodeling | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 4 | 23 |
GO:0005844 | polysome | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 4 | 23 |
GO:0031463 | Cul3-RING ubiquitin ligase complex | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 3 | 23 |
GO:0043236 | laminin binding | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 1 | 23 |
GO:0006513 | protein monoubiquitination | 2.37e-02 | 1.00e+00 | 5.386 | 1 | 1 | 23 |
GO:0034080 | CENP-A containing nucleosome assembly | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 1 | 25 |
GO:0000722 | telomere maintenance via recombination | 2.57e-02 | 1.00e+00 | 5.265 | 1 | 5 | 25 |
GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 3 | 26 |
GO:0043022 | ribosome binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 3 | 27 |
GO:0050661 | NADP binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 2 | 27 |
GO:0071339 | MLL1 complex | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 3 | 27 |
GO:0043967 | histone H4 acetylation | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 3 | 27 |
GO:0031492 | nucleosomal DNA binding | 2.77e-02 | 1.00e+00 | 5.154 | 1 | 4 | 27 |
GO:0006099 | tricarboxylic acid cycle | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 4 | 28 |
GO:0019894 | kinesin binding | 2.87e-02 | 1.00e+00 | 5.102 | 1 | 1 | 28 |
GO:0019005 | SCF ubiquitin ligase complex | 2.98e-02 | 1.00e+00 | 5.051 | 1 | 1 | 29 |
GO:0006271 | DNA strand elongation involved in DNA replication | 3.08e-02 | 1.00e+00 | 5.002 | 1 | 7 | 30 |
GO:0019899 | enzyme binding | 3.27e-02 | 1.00e+00 | 2.795 | 2 | 12 | 277 |
GO:0006633 | fatty acid biosynthetic process | 3.28e-02 | 1.00e+00 | 4.909 | 1 | 3 | 32 |
GO:0001895 | retina homeostasis | 3.48e-02 | 1.00e+00 | 4.822 | 1 | 1 | 34 |
GO:0051539 | 4 iron, 4 sulfur cluster binding | 3.58e-02 | 1.00e+00 | 4.780 | 1 | 3 | 35 |
GO:0034332 | adherens junction organization | 3.68e-02 | 1.00e+00 | 4.739 | 1 | 1 | 36 |
GO:0051084 | 'de novo' posttranslational protein folding | 3.78e-02 | 1.00e+00 | 4.700 | 1 | 4 | 37 |
GO:0006284 | base-excision repair | 3.78e-02 | 1.00e+00 | 4.700 | 1 | 3 | 37 |
GO:0070527 | platelet aggregation | 3.88e-02 | 1.00e+00 | 4.661 | 1 | 2 | 38 |
GO:0022627 | cytosolic small ribosomal subunit | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 4 | 39 |
GO:0000781 | chromosome, telomeric region | 3.98e-02 | 1.00e+00 | 4.624 | 1 | 3 | 39 |
GO:0032508 | DNA duplex unwinding | 4.18e-02 | 1.00e+00 | 4.552 | 1 | 3 | 41 |
GO:0014070 | response to organic cyclic compound | 4.38e-02 | 1.00e+00 | 4.483 | 1 | 4 | 43 |
GO:0021762 | substantia nigra development | 4.48e-02 | 1.00e+00 | 4.450 | 1 | 2 | 44 |
GO:0006283 | transcription-coupled nucleotide-excision repair | 4.68e-02 | 1.00e+00 | 4.386 | 1 | 7 | 46 |
GO:0003684 | damaged DNA binding | 4.98e-02 | 1.00e+00 | 4.294 | 1 | 7 | 49 |
GO:0006091 | generation of precursor metabolites and energy | 5.08e-02 | 1.00e+00 | 4.265 | 1 | 3 | 50 |
GO:0040008 | regulation of growth | 5.08e-02 | 1.00e+00 | 4.265 | 1 | 5 | 50 |
GO:0051289 | protein homotetramerization | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 1 | 51 |
GO:0030674 | protein binding, bridging | 5.18e-02 | 1.00e+00 | 4.237 | 1 | 1 | 51 |
GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 5.38e-02 | 1.00e+00 | 4.181 | 1 | 5 | 53 |
GO:0045216 | cell-cell junction organization | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 2 | 54 |
GO:0000932 | cytoplasmic mRNA processing body | 5.47e-02 | 1.00e+00 | 4.154 | 1 | 3 | 54 |
GO:0000724 | double-strand break repair via homologous recombination | 5.57e-02 | 1.00e+00 | 4.128 | 1 | 3 | 55 |
GO:0000723 | telomere maintenance | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 6 | 56 |
GO:0012505 | endomembrane system | 5.67e-02 | 1.00e+00 | 4.102 | 1 | 2 | 56 |
GO:0042995 | cell projection | 6.06e-02 | 1.00e+00 | 4.002 | 1 | 6 | 60 |
GO:0019903 | protein phosphatase binding | 6.26e-02 | 1.00e+00 | 3.955 | 1 | 4 | 62 |
GO:0006302 | double-strand break repair | 6.26e-02 | 1.00e+00 | 3.955 | 1 | 4 | 62 |
GO:0006310 | DNA recombination | 6.55e-02 | 1.00e+00 | 3.887 | 1 | 2 | 65 |
GO:0006289 | nucleotide-excision repair | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 11 | 68 |
GO:0006767 | water-soluble vitamin metabolic process | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 1 | 68 |
GO:0034329 | cell junction assembly | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 1 | 68 |
GO:0003697 | single-stranded DNA binding | 6.85e-02 | 1.00e+00 | 3.822 | 1 | 5 | 68 |
GO:0006766 | vitamin metabolic process | 7.14e-02 | 1.00e+00 | 3.759 | 1 | 1 | 71 |
GO:0006334 | nucleosome assembly | 7.24e-02 | 1.00e+00 | 3.739 | 1 | 2 | 72 |
GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 7.53e-02 | 1.00e+00 | 3.680 | 1 | 2 | 75 |
GO:0019083 | viral transcription | 8.10e-02 | 1.00e+00 | 3.569 | 1 | 10 | 81 |
GO:0044267 | cellular protein metabolic process | 8.54e-02 | 1.00e+00 | 2.020 | 2 | 29 | 474 |
GO:0047485 | protein N-terminus binding | 8.58e-02 | 1.00e+00 | 3.483 | 1 | 5 | 86 |
GO:0006415 | translational termination | 8.68e-02 | 1.00e+00 | 3.466 | 1 | 10 | 87 |
GO:0016605 | PML body | 8.78e-02 | 1.00e+00 | 3.450 | 1 | 3 | 88 |
GO:0016363 | nuclear matrix | 9.06e-02 | 1.00e+00 | 3.401 | 1 | 12 | 91 |
GO:0006928 | cellular component movement | 9.06e-02 | 1.00e+00 | 3.401 | 1 | 7 | 91 |
GO:0051015 | actin filament binding | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 2 | 92 |
GO:0071456 | cellular response to hypoxia | 9.16e-02 | 1.00e+00 | 3.386 | 1 | 6 | 92 |
GO:0006414 | translational elongation | 9.25e-02 | 1.00e+00 | 3.370 | 1 | 13 | 93 |
GO:0006112 | energy reserve metabolic process | 9.44e-02 | 1.00e+00 | 3.339 | 1 | 3 | 95 |
GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 10 | 104 |
GO:0014069 | postsynaptic density | 1.04e-01 | 1.00e+00 | 3.195 | 1 | 3 | 105 |
GO:0005506 | iron ion binding | 1.04e-01 | 1.00e+00 | 3.195 | 1 | 4 | 105 |
GO:0005741 | mitochondrial outer membrane | 1.04e-01 | 1.00e+00 | 3.195 | 1 | 7 | 105 |
GO:0005815 | microtubule organizing center | 1.08e-01 | 1.00e+00 | 3.141 | 1 | 5 | 109 |
GO:0072562 | blood microparticle | 1.09e-01 | 1.00e+00 | 3.115 | 1 | 3 | 111 |
GO:0015630 | microtubule cytoskeleton | 1.09e-01 | 1.00e+00 | 3.128 | 1 | 4 | 110 |
GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 1.12e-01 | 1.00e+00 | 3.076 | 1 | 11 | 114 |
GO:0019058 | viral life cycle | 1.13e-01 | 1.00e+00 | 3.064 | 1 | 13 | 115 |
GO:0044237 | cellular metabolic process | 1.15e-01 | 1.00e+00 | 3.039 | 1 | 5 | 117 |
GO:0007219 | Notch signaling pathway | 1.18e-01 | 1.00e+00 | 3.002 | 1 | 5 | 120 |
GO:0006260 | DNA replication | 1.19e-01 | 1.00e+00 | 2.990 | 1 | 9 | 121 |
GO:0006511 | ubiquitin-dependent protein catabolic process | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 5 | 126 |
GO:0009615 | response to virus | 1.23e-01 | 1.00e+00 | 2.932 | 1 | 5 | 126 |
GO:0000790 | nuclear chromatin | 1.26e-01 | 1.00e+00 | 2.898 | 1 | 9 | 129 |
GO:0045087 | innate immune response | 1.26e-01 | 1.00e+00 | 1.690 | 2 | 24 | 596 |
GO:0006413 | translational initiation | 1.28e-01 | 1.00e+00 | 2.876 | 1 | 17 | 131 |
GO:0044255 | cellular lipid metabolic process | 1.30e-01 | 1.00e+00 | 2.854 | 1 | 6 | 133 |
GO:0003735 | structural constituent of ribosome | 1.33e-01 | 1.00e+00 | 2.811 | 1 | 10 | 137 |
GO:0016887 | ATPase activity | 1.36e-01 | 1.00e+00 | 2.780 | 1 | 7 | 140 |
GO:0006457 | protein folding | 1.39e-01 | 1.00e+00 | 2.749 | 1 | 7 | 143 |
GO:0061024 | membrane organization | 1.41e-01 | 1.00e+00 | 2.729 | 1 | 7 | 145 |
GO:0005524 | ATP binding | 1.47e-01 | 1.00e+00 | 1.152 | 3 | 60 | 1298 |
GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.59e-01 | 1.00e+00 | 2.543 | 1 | 7 | 165 |
GO:0030424 | axon | 1.59e-01 | 1.00e+00 | 2.534 | 1 | 4 | 166 |
GO:0032403 | protein complex binding | 1.74e-01 | 1.00e+00 | 2.393 | 1 | 10 | 183 |
GO:0007067 | mitotic nuclear division | 2.12e-01 | 1.00e+00 | 2.083 | 1 | 14 | 227 |
GO:0005759 | mitochondrial matrix | 2.13e-01 | 1.00e+00 | 2.076 | 1 | 14 | 228 |
GO:0006412 | translation | 2.14e-01 | 1.00e+00 | 2.064 | 1 | 20 | 230 |
GO:0005975 | carbohydrate metabolic process | 2.33e-01 | 1.00e+00 | 1.926 | 1 | 9 | 253 |
GO:0004842 | ubiquitin-protein transferase activity | 2.35e-01 | 1.00e+00 | 1.915 | 1 | 6 | 255 |
GO:0007283 | spermatogenesis | 2.41e-01 | 1.00e+00 | 1.876 | 1 | 8 | 262 |
GO:0006357 | regulation of transcription from RNA polymerase II promoter | 2.42e-01 | 1.00e+00 | 1.865 | 1 | 8 | 264 |
GO:0042493 | response to drug | 2.58e-01 | 1.00e+00 | 1.759 | 1 | 13 | 284 |
GO:0005856 | cytoskeleton | 2.64e-01 | 1.00e+00 | 1.724 | 1 | 12 | 291 |
GO:0043234 | protein complex | 2.67e-01 | 1.00e+00 | 1.705 | 1 | 18 | 295 |
GO:0016567 | protein ubiquitination | 2.67e-01 | 1.00e+00 | 1.705 | 1 | 5 | 295 |
GO:0005739 | mitochondrion | 2.79e-01 | 1.00e+00 | 0.946 | 2 | 28 | 998 |
GO:0019901 | protein kinase binding | 2.84e-01 | 1.00e+00 | 1.601 | 1 | 21 | 317 |
GO:0043231 | intracellular membrane-bounded organelle | 2.84e-01 | 1.00e+00 | 1.596 | 1 | 9 | 318 |
GO:0007411 | axon guidance | 2.85e-01 | 1.00e+00 | 1.592 | 1 | 13 | 319 |
GO:0005813 | centrosome | 2.90e-01 | 1.00e+00 | 1.560 | 1 | 14 | 326 |
GO:0003723 | RNA binding | 3.02e-01 | 1.00e+00 | 1.491 | 1 | 20 | 342 |
GO:0005925 | focal adhesion | 3.20e-01 | 1.00e+00 | 1.393 | 1 | 19 | 366 |
GO:0007155 | cell adhesion | 3.22e-01 | 1.00e+00 | 1.382 | 1 | 6 | 369 |
GO:0055114 | oxidation-reduction process | 3.58e-01 | 1.00e+00 | 1.195 | 1 | 12 | 420 |
GO:0007596 | blood coagulation | 3.82e-01 | 1.00e+00 | 1.079 | 1 | 18 | 455 |
GO:0042803 | protein homodimerization activity | 4.69e-01 | 1.00e+00 | 0.692 | 1 | 12 | 595 |
GO:0005794 | Golgi apparatus | 4.77e-01 | 1.00e+00 | 0.657 | 1 | 15 | 610 |
GO:0005737 | cytoplasm | 5.78e-01 | 1.00e+00 | 0.030 | 4 | 110 | 3767 |
GO:0005615 | extracellular space | 6.43e-01 | 1.00e+00 | 0.007 | 1 | 17 | 957 |
GO:0008270 | zinc ion binding | 6.59e-01 | 1.00e+00 | -0.052 | 1 | 12 | 997 |
GO:0044822 | poly(A) RNA binding | 6.81e-01 | 1.00e+00 | -0.135 | 1 | 49 | 1056 |
GO:0046872 | metal ion binding | 7.60e-01 | 1.00e+00 | -0.443 | 1 | 25 | 1307 |
GO:0006351 | transcription, DNA-templated | 7.95e-01 | 1.00e+00 | -0.589 | 1 | 31 | 1446 |
GO:0005886 | plasma membrane | 9.48e-01 | 1.00e+00 | -1.425 | 1 | 45 | 2582 |