meta-int-snw-6233

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-60 tai-screen-luciferase 4.243 1.88e-19 3.43e-03 4.71e-03 12 5
int-snw-6233 tai-screen-luciferase 8.389 3.07e-257 1.78e-14 1.14e-06 7 7
reg-snw-1121 tai-screen-luciferase 4.707 1.91e-24 5.19e-04 8.44e-04 5 3
reg-snw-821 tai-screen-luciferase 4.344 1.76e-20 2.34e-03 3.35e-03 11 4
reg-snw-51164 tai-screen-luciferase 4.586 4.41e-23 8.78e-04 1.37e-03 6 4
reg-snw-57120 tai-screen-luciferase 4.450 1.33e-21 1.54e-03 2.29e-03 12 6
tai-screen-luciferase-meta-int-snw-6233 subnetwork

Genes (28)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
HES4 57801 19-4.1534.45010--
DMD 1756 15-4.3384.24353--
COPA 1314 48-9.3955.672340YesYes
PAFAH1B1 5048 18-2.5834.58655Yes-
GOPC 57120 191.7494.45068--
CAPRIN1 4076 14-2.2264.68842--
TNFRSF8 943 19-4.1064.45015--
CUL4B 8450 21-2.8095.269142--
HSF1 3297 46-4.1795.027209-Yes
ARFGEF1 10565 13-2.7224.34415--
RPS24 6229 46-7.0348.389217Yes-
CANX 821 17-1.9594.50465--
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
DNAJC10 54431 13-2.3494.34411--
COPZ1 22818 48-8.3019.06313YesYes
RB1 5925 21-2.0854.707351--
EIF2S2 8894 31-4.3205.672103Yes-
CHM 1121 13-0.4834.7072--
CDC42 998 44-6.9604.707276YesYes
RPS27A 6233 45-5.6318.389344Yes-
DCTN4 51164 13-1.8824.58619--
MRPS12 6183 35-5.4215.516341Yes-
SRF 6722 151.9944.24323--
ACTB 60 15-1.7164.24323--
ARCN1 372 48-8.2329.063118YesYes
SERBP1 26135 35-4.6125.516106-Yes
CDC5L 988 34-3.4195.672155--

Interactions (56)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
TNFRSF8 943 RB1 5925 pd < reg.pazar.txt: no annot
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
PAFAH1B1 5048 ARFGEF1 10565 pd > reg.ITFP.txt: no annot
ACTB 60 CANX 821 pd < reg.ITFP.txt: no annot
COPA 1314 RB1 5925 pd <> reg.ITFP.txt: no annot
HSF1 3297 SRF 6722 pd <> reg.ITFP.txt: no annot
HSF1 3297 SRF 6722 pp -- int.Yu: muscle
COPA 1314 DCTN4 51164 pd > reg.ITFP.txt: no annot
CDC5L 988 CUL4B 8450 pd <> reg.ITFP.txt: no annot
RB1 5925 GOPC 57120 pd > reg.ITFP.txt: no annot
CANX 821 ARFGEF1 10565 pd > reg.ITFP.txt: no annot
CANX 821 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
RB1 5925 HES4 57801 pd > reg.pazar.txt: no annot
CHM 1121 COPA 1314 pd < reg.ITFP.txt: no annot
RB1 5925 SERBP1 26135 pd > reg.pazar.txt: no annot
ACTB 60 MRPS12 6183 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPS24 6229 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS27A 6233 ARFGEF1 10565 pp -- int.I2D: YeastLow
CUL4B 8450 GOPC 57120 pd > reg.ITFP.txt: no annot
PAFAH1B1 5048 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
PAFAH1B1 5048 GOPC 57120 pd > reg.ITFP.txt: no annot
CAPRIN1 4076 CKAP5 9793 pd < reg.ITFP.txt: no annot
CDC42 998 ARFGEF1 10565 pp -- int.I2D: IntAct, SOURAV_MAPK_LOW
ACTB 60 RB1 5925 pd < reg.ITFP.txt: no annot
ACTB 60 COPA 1314 pd < reg.ITFP.txt: no annot
ACTB 60 COPA 1314 pp -- int.I2D: BioGrid_Yeast
CAPRIN1 4076 CUL4B 8450 pd < reg.ITFP.txt: no annot
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
PAFAH1B1 5048 DCTN4 51164 pd > reg.ITFP.txt: no annot
DMD 1756 SRF 6722 pd < reg.pazar.txt: no annot;
reg.TRANSFAC.txt: no annot
CANX 821 RB1 5925 pd <> reg.ITFP.txt: no annot
ACTB 60 PAFAH1B1 5048 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
CANX 821 MRPS12 6183 pp -- int.I2D: BioGrid_Yeast
CDC42 998 GOPC 57120 pp -- int.I2D: BioGrid
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
CANX 821 COPA 1314 pd <> reg.ITFP.txt: no annot
COPA 1314 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
ACTB 60 ARCN1 372 pp -- int.I2D: BioGrid_Yeast
CUL4B 8450 DNAJC10 54431 pd > reg.ITFP.txt: no annot
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RB1 5925 DCTN4 51164 pd > reg.ITFP.txt: no annot
COPA 1314 GOPC 57120 pd > reg.ITFP.txt: no annot
CDC5L 988 GOPC 57120 pd > reg.ITFP.txt: no annot
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
COPA 1314 CUL4B 8450 pd <> reg.ITFP.txt: no annot
CDC5L 988 EIF2S2 8894 pd > reg.ITFP.txt: no annot
CHM 1121 RB1 5925 pd < reg.ITFP.txt: no annot
CANX 821 DCTN4 51164 pd > reg.ITFP.txt: no annot
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
CDC42 998 RB1 5925 pd < reg.pazar.txt: no annot
CANX 821 DNAJC10 54431 pd > reg.ITFP.txt: no annot
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
ACTB 60 SRF 6722 pd < reg.pazar.txt: no annot;
reg.oreganno.txt: no annot
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
COPA 1314 PAFAH1B1 5048 pd <> reg.ITFP.txt: no annot

Related GO terms (578)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0048205COPI coating of Golgi vesicle4.90e-098.00e-057.4874613
GO:0030126COPI vesicle coat4.90e-098.00e-057.4874613
GO:0006890retrograde vesicle-mediated transport, Golgi to ER8.55e-081.40e-036.5434625
GO:0061024membrane organization1.48e-072.42e-034.582611146
GO:0005829cytosol5.94e-079.69e-031.86416742562
GO:0016020membrane1.83e-062.99e-022.11813481746
GO:0015935small ribosomal subunit3.03e-064.94e-026.6853917
GO:0043234protein complex9.83e-061.60e-013.54369300
GO:0044822poly(A) RNA binding5.08e-058.29e-012.2839421078
GO:0007097nuclear migration5.93e-059.68e-017.380227
GO:0090136epithelial cell-cell adhesion1.01e-041.00e+007.017229
GO:0006886intracellular protein transport2.05e-041.00e+003.75246173
GO:0050998nitric-oxide synthase binding3.36e-041.00e+006.1872316
GO:0006891intra-Golgi vesicle-mediated transport3.80e-041.00e+006.1002317
GO:0017022myosin binding4.27e-041.00e+006.0172218
GO:0009306protein secretion5.84e-041.00e+005.7952221
GO:0036464cytoplasmic ribonucleoprotein granule6.42e-041.00e+005.7282522
GO:0006412translation6.54e-041.00e+003.311429235
GO:0005737cytoplasm8.29e-041.00e+001.13715653976
GO:0051219phosphoprotein binding1.36e-031.00e+005.1872432
GO:0044267cellular protein metabolic process1.39e-031.00e+002.558529495
GO:0006413translational initiation1.43e-031.00e+003.739327131
GO:0000086G2/M transition of mitotic cell cycle1.63e-031.00e+003.67436137
GO:0030038contractile actin filament bundle assembly1.72e-031.00e+009.187111
GO:0045556positive regulation of TRAIL biosynthetic process1.72e-031.00e+009.187111
GO:0034332adherens junction organization1.72e-031.00e+005.0172436
GO:0090287regulation of cellular response to growth factor stimulus1.72e-031.00e+009.187111
GO:0000235astral microtubule1.72e-031.00e+009.187111
GO:0090284positive regulation of protein glycosylation in Golgi1.72e-031.00e+009.187111
GO:0090230regulation of centromere complex assembly1.72e-031.00e+009.187111
GO:0043004cytoplasmic sequestering of CFTR protein1.72e-031.00e+009.187111
GO:0021691cerebellar Purkinje cell layer maturation1.72e-031.00e+009.187111
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway1.72e-031.00e+005.0172336
GO:0051660establishment of centrosome localization1.72e-031.00e+009.187111
GO:0034975protein folding in endoplasmic reticulum1.72e-031.00e+009.187111
GO:0046016positive regulation of transcription by glucose1.72e-031.00e+009.187111
GO:0046469platelet activating factor metabolic process1.72e-031.00e+009.187111
GO:0003735structural constituent of ribosome1.77e-031.00e+003.632324141
GO:0021766hippocampus development2.02e-031.00e+004.9022339
GO:0022627cytosolic small ribosomal subunit2.02e-031.00e+004.90222139
GO:0034613cellular protein localization2.57e-031.00e+004.7282244
GO:0021762substantia nigra development2.80e-031.00e+004.6642246
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding2.90e-031.00e+003.38034168
GO:0008344adult locomotory behavior2.93e-031.00e+004.6322247
GO:0030424axon3.10e-031.00e+003.34634172
GO:0007030Golgi organization3.30e-031.00e+004.5432350
GO:0010256endomembrane system organization3.43e-031.00e+008.187112
GO:0071987WD40-repeat domain binding3.43e-031.00e+008.187112
GO:0060661submandibular salivary gland formation3.43e-031.00e+008.187112
GO:0036035osteoclast development3.43e-031.00e+008.187112
GO:0014819regulation of skeletal muscle contraction3.43e-031.00e+008.187112
GO:0086001cardiac muscle cell action potential3.43e-031.00e+008.187112
GO:0071338positive regulation of hair follicle cell proliferation3.43e-031.00e+008.187112
GO:0051081nuclear envelope disassembly3.43e-031.00e+008.187112
GO:0002176male germ cell proliferation3.43e-031.00e+008.187112
GO:0072422signal transduction involved in DNA damage checkpoint3.43e-031.00e+008.187112
GO:0090135actin filament branching3.43e-031.00e+008.187112
GO:0031134sister chromatid biorientation3.43e-031.00e+008.187112
GO:0010736serum response element binding3.43e-031.00e+008.187112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis3.43e-031.00e+008.187112
GO:0030175filopodium3.71e-031.00e+004.4592253
GO:0000278mitotic cell cycle4.49e-031.00e+002.550416398
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding5.14e-031.00e+007.602113
GO:0014809regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion5.14e-031.00e+007.602113
GO:0060947cardiac vascular smooth muscle cell differentiation5.14e-031.00e+007.602113
GO:0003161cardiac conduction system development5.14e-031.00e+007.602113
GO:0071459protein localization to chromosome, centromeric region5.14e-031.00e+007.602113
GO:1900222negative regulation of beta-amyloid clearance5.14e-031.00e+007.602113
GO:1901385regulation of voltage-gated calcium channel activity5.14e-031.00e+007.602113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle5.14e-031.00e+007.602113
GO:0045505dynein intermediate chain binding5.14e-031.00e+007.602113
GO:0051683establishment of Golgi localization5.14e-031.00e+007.602123
GO:0022028tangential migration from the subventricular zone to the olfactory bulb5.14e-031.00e+007.602113
GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor5.14e-031.00e+007.602113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity5.14e-031.00e+007.602113
GO:0033561regulation of water loss via skin5.14e-031.00e+007.602113
GO:0005850eukaryotic translation initiation factor 2 complex5.14e-031.00e+007.602113
GO:0034663endoplasmic reticulum chaperone complex5.14e-031.00e+007.602113
GO:1902083negative regulation of peptidyl-cysteine S-nitrosylation5.14e-031.00e+007.602123
GO:0021540corpus callosum morphogenesis5.14e-031.00e+007.602113
GO:0071922regulation of cohesin localization to chromatin6.85e-031.00e+007.187124
GO:0034191apolipoprotein A-I receptor binding6.85e-031.00e+007.187114
GO:0010669epithelial structure maintenance6.85e-031.00e+007.187114
GO:0060684epithelial-mesenchymal cell signaling6.85e-031.00e+007.187114
GO:0051835positive regulation of synapse structural plasticity6.85e-031.00e+007.187114
GO:0015036disulfide oxidoreductase activity6.85e-031.00e+007.187114
GO:0043550regulation of lipid kinase activity6.85e-031.00e+007.187114
GO:0016013syntrophin complex6.85e-031.00e+007.187124
GO:0090231regulation of spindle checkpoint6.85e-031.00e+007.187114
GO:0072384organelle transport along microtubule6.85e-031.00e+007.187124
GO:0003257positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation6.85e-031.00e+007.187114
GO:0048664neuron fate determination6.85e-031.00e+007.187114
GO:0010735positive regulation of transcription via serum response element binding6.85e-031.00e+007.187114
GO:0005968Rab-protein geranylgeranyltransferase complex6.85e-031.00e+007.187114
GO:0035189Rb-E2F complex6.85e-031.00e+007.187114
GO:0034349glial cell apoptotic process6.85e-031.00e+007.187114
GO:0034088maintenance of mitotic sister chromatid cohesion6.85e-031.00e+007.187114
GO:0031175neuron projection development7.29e-031.00e+003.9582275
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis7.67e-031.00e+003.9202477
GO:0008134transcription factor binding8.39e-031.00e+002.83035246
GO:0019083viral transcription8.46e-031.00e+003.84722281
GO:0036336dendritic cell migration8.55e-031.00e+006.865115
GO:2000651positive regulation of sodium ion transmembrane transporter activity8.55e-031.00e+006.865115
GO:0035088establishment or maintenance of apical/basal cell polarity8.55e-031.00e+006.865115
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)8.55e-031.00e+006.865135
GO:0048667cell morphogenesis involved in neuron differentiation8.55e-031.00e+006.865115
GO:0031256leading edge membrane8.55e-031.00e+006.865115
GO:0044233ER-mitochondrion membrane contact site8.55e-031.00e+006.865115
GO:0035912dorsal aorta morphogenesis8.55e-031.00e+006.865115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex8.55e-031.00e+006.865115
GO:0043043peptide biosynthetic process8.55e-031.00e+006.865115
GO:0031023microtubule organizing center organization8.55e-031.00e+006.865115
GO:0004663Rab geranylgeranyltransferase activity8.55e-031.00e+006.865115
GO:0043025neuronal cell body9.16e-031.00e+002.78335254
GO:0006415translational termination9.70e-031.00e+003.74422287
GO:0043353enucleate erythrocyte differentiation1.03e-021.00e+006.602116
GO:0007143female meiotic division1.03e-021.00e+006.602116
GO:0044458motile cilium assembly1.03e-021.00e+006.602116
GO:0051150regulation of smooth muscle cell differentiation1.03e-021.00e+006.602116
GO:0018344protein geranylgeranylation1.03e-021.00e+006.602116
GO:0060789hair follicle placode formation1.03e-021.00e+006.602116
GO:0008090retrograde axon cargo transport1.03e-021.00e+006.602116
GO:0048554positive regulation of metalloenzyme activity1.03e-021.00e+006.602116
GO:0045842positive regulation of mitotic metaphase/anaphase transition1.03e-021.00e+006.602116
GO:0001667ameboidal-type cell migration1.03e-021.00e+006.602116
GO:0000974Prp19 complex1.03e-021.00e+006.602116
GO:0030957Tat protein binding1.03e-021.00e+006.602116
GO:0034452dynactin binding1.03e-021.00e+006.602116
GO:0005515protein binding1.07e-021.00e+000.69417876127
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II1.08e-021.00e+003.6642392
GO:0005200structural constituent of cytoskeleton1.10e-021.00e+003.6482693
GO:0006414translational elongation1.10e-021.00e+003.64822293
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.13e-021.00e+003.6322794
GO:0001764neuron migration1.17e-021.00e+003.6022296
GO:0060261positive regulation of transcription initiation from RNA polymerase II promoter1.19e-021.00e+006.380117
GO:0006893Golgi to plasma membrane transport1.19e-021.00e+006.380117
GO:0060055angiogenesis involved in wound healing1.19e-021.00e+006.380117
GO:0060136embryonic process involved in female pregnancy1.19e-021.00e+006.380117
GO:0043497regulation of protein heterodimerization activity1.19e-021.00e+006.380117
GO:0050658RNA transport1.19e-021.00e+006.380117
GO:0003334keratinocyte development1.19e-021.00e+006.380117
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.19e-021.00e+006.380117
GO:0070914UV-damage excision repair1.19e-021.00e+006.380117
GO:0001961positive regulation of cytokine-mediated signaling pathway1.19e-021.00e+006.380117
GO:0034101erythrocyte homeostasis1.19e-021.00e+006.380117
GO:0002162dystroglycan binding1.19e-021.00e+006.380117
GO:0030157pancreatic juice secretion1.19e-021.00e+006.380117
GO:0017145stem cell division1.19e-021.00e+006.380117
GO:0000930gamma-tubulin complex1.19e-021.00e+006.380117
GO:0034259negative regulation of Rho GTPase activity1.19e-021.00e+006.380117
GO:0090009primitive streak formation1.36e-021.00e+006.187118
GO:0031512motile primary cilium1.36e-021.00e+006.187118
GO:0043589skin morphogenesis1.36e-021.00e+006.187118
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.36e-021.00e+003.487222104
GO:0007289spermatid nucleus differentiation1.36e-021.00e+006.187118
GO:0070688MLL5-L complex1.36e-021.00e+006.187118
GO:0005869dynactin complex1.36e-021.00e+006.187118
GO:0051489regulation of filopodium assembly1.36e-021.00e+006.187118
GO:0061003positive regulation of dendritic spine morphogenesis1.36e-021.00e+006.187118
GO:0014069postsynaptic density1.41e-021.00e+003.45923106
GO:0097284hepatocyte apoptotic process1.53e-021.00e+006.017119
GO:0000983RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity1.53e-021.00e+006.017119
GO:0000075cell cycle checkpoint1.53e-021.00e+006.017119
GO:0021895cerebral cortex neuron differentiation1.53e-021.00e+006.017119
GO:0030837negative regulation of actin filament polymerization1.53e-021.00e+006.017119
GO:0032319regulation of Rho GTPase activity1.53e-021.00e+006.017119
GO:0045059positive thymic T cell selection1.53e-021.00e+006.017119
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.62e-021.00e+003.354222114
GO:0019058viral life cycle1.65e-021.00e+003.342225115
GO:0034237protein kinase A regulatory subunit binding1.70e-021.00e+005.8651110
GO:0051787misfolded protein binding1.70e-021.00e+005.8651110
GO:0042535positive regulation of tumor necrosis factor biosynthetic process1.70e-021.00e+005.8651110
GO:0031274positive regulation of pseudopodium assembly1.70e-021.00e+005.8651210
GO:0001076RNA polymerase II transcription factor binding transcription factor activity1.70e-021.00e+005.8651110
GO:0090303positive regulation of wound healing1.70e-021.00e+005.8651110
GO:0061029eyelid development in camera-type eye1.70e-021.00e+005.8651110
GO:0001675acrosome assembly1.70e-021.00e+005.8651110
GO:0060218hematopoietic stem cell differentiation1.70e-021.00e+005.8651110
GO:0060047heart contraction1.70e-021.00e+005.8651110
GO:0045502dynein binding1.87e-021.00e+005.7281111
GO:0045176apical protein localization1.87e-021.00e+005.7281111
GO:0017166vinculin binding1.87e-021.00e+005.7281111
GO:0042551neuron maturation1.87e-021.00e+005.7281111
GO:0045651positive regulation of macrophage differentiation1.87e-021.00e+005.7281111
GO:0045120pronucleus1.87e-021.00e+005.7281111
GO:0035518histone H2A monoubiquitination1.87e-021.00e+005.7281211
GO:0002011morphogenesis of an epithelial sheet1.87e-021.00e+005.7281111
GO:0021819layer formation in cerebral cortex1.87e-021.00e+005.7281111
GO:0005813centrosome1.98e-021.00e+002.36739339
GO:0007051spindle organization2.04e-021.00e+005.6021112
GO:0051146striated muscle cell differentiation2.04e-021.00e+005.6021212
GO:0042274ribosomal small subunit biogenesis2.04e-021.00e+005.6021612
GO:0043149stress fiber assembly2.04e-021.00e+005.6021212
GO:0019082viral protein processing2.04e-021.00e+005.6021212
GO:0030140trans-Golgi network transport vesicle2.04e-021.00e+005.6021112
GO:0072583clathrin-mediated endocytosis2.04e-021.00e+005.6021112
GO:0047496vesicle transport along microtubule2.04e-021.00e+005.6021112
GO:0055003cardiac myofibril assembly2.04e-021.00e+005.6021112
GO:0030036actin cytoskeleton organization2.05e-021.00e+003.17623129
GO:0070062extracellular vesicular exosome2.08e-021.00e+001.0609512516
GO:0000790nuclear chromatin2.17e-021.00e+003.13222133
GO:0042789mRNA transcription from RNA polymerase II promoter2.21e-021.00e+005.4871113
GO:0001671ATPase activator activity2.21e-021.00e+005.4871113
GO:0043488regulation of mRNA stability2.21e-021.00e+005.4871113
GO:0032479regulation of type I interferon production2.21e-021.00e+005.4871213
GO:0005662DNA replication factor A complex2.21e-021.00e+005.4871113
GO:1900087positive regulation of G1/S transition of mitotic cell cycle2.21e-021.00e+005.4871113
GO:0060314regulation of ryanodine-sensitive calcium-release channel activity2.21e-021.00e+005.4871113
GO:0035855megakaryocyte development2.21e-021.00e+005.4871113
GO:0035371microtubule plus-end2.38e-021.00e+005.3801114
GO:0031333negative regulation of protein complex assembly2.38e-021.00e+005.3801114
GO:0060292long term synaptic depression2.38e-021.00e+005.3801114
GO:0048488synaptic vesicle endocytosis2.38e-021.00e+005.3801114
GO:0035267NuA4 histone acetyltransferase complex2.38e-021.00e+005.3801214
GO:0031996thioesterase binding2.38e-021.00e+005.3801114
GO:0034185apolipoprotein binding2.38e-021.00e+005.3801114
GO:0008285negative regulation of cell proliferation2.44e-021.00e+002.25233367
GO:0030131clathrin adaptor complex2.54e-021.00e+005.2801115
GO:0002042cell migration involved in sprouting angiogenesis2.54e-021.00e+005.2801115
GO:0030225macrophage differentiation2.54e-021.00e+005.2801115
GO:0016514SWI/SNF complex2.54e-021.00e+005.2801115
GO:0045987positive regulation of smooth muscle contraction2.54e-021.00e+005.2801115
GO:0045445myoblast differentiation2.54e-021.00e+005.2801115
GO:0048821erythrocyte development2.54e-021.00e+005.2801215
GO:0016010dystrophin-associated glycoprotein complex2.54e-021.00e+005.2801115
GO:0031369translation initiation factor binding2.54e-021.00e+005.2801215
GO:2000114regulation of establishment of cell polarity2.54e-021.00e+005.2801115
GO:0051233spindle midzone2.54e-021.00e+005.2801215
GO:0048854brain morphogenesis2.54e-021.00e+005.2801115
GO:0060347heart trabecula formation2.54e-021.00e+005.2801115
GO:0006457protein folding2.68e-021.00e+002.96823149
GO:0032839dendrite cytoplasm2.71e-021.00e+005.1871116
GO:0007405neuroblast proliferation2.71e-021.00e+005.1871116
GO:0032012regulation of ARF protein signal transduction2.71e-021.00e+005.1871116
GO:0019226transmission of nerve impulse2.71e-021.00e+005.1871116
GO:0000132establishment of mitotic spindle orientation2.71e-021.00e+005.1871216
GO:0042176regulation of protein catabolic process2.71e-021.00e+005.1871416
GO:0033137negative regulation of peptidyl-serine phosphorylation2.71e-021.00e+005.1871116
GO:0030220platelet formation2.71e-021.00e+005.1871116
GO:0043623cellular protein complex assembly2.71e-021.00e+005.1871116
GO:0046716muscle cell cellular homeostasis2.71e-021.00e+005.1871116
GO:0000082G1/S transition of mitotic cell cycle2.71e-021.00e+002.958211150
GO:0050775positive regulation of dendrite morphogenesis2.71e-021.00e+005.1871116
GO:0042981regulation of apoptotic process2.75e-021.00e+002.94927151
GO:0035255ionotropic glutamate receptor binding2.88e-021.00e+005.1001117
GO:0010880regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum2.88e-021.00e+005.1001117
GO:0075733intracellular transport of virus2.88e-021.00e+005.1001317
GO:0043274phospholipase binding2.88e-021.00e+005.1001117
GO:0019068virion assembly2.88e-021.00e+005.1001217
GO:0008306associative learning2.88e-021.00e+005.1001117
GO:0031527filopodium membrane2.88e-021.00e+005.1001117
GO:0001829trophectodermal cell differentiation2.88e-021.00e+005.1001117
GO:0030742GTP-dependent protein binding2.88e-021.00e+005.1001117
GO:0005788endoplasmic reticulum lumen2.95e-021.00e+002.89222157
GO:0005198structural molecule activity3.02e-021.00e+002.87425159
GO:0006612protein targeting to membrane3.04e-021.00e+005.0171218
GO:0045773positive regulation of axon extension3.04e-021.00e+005.0171118
GO:0005086ARF guanyl-nucleotide exchange factor activity3.04e-021.00e+005.0171118
GO:0090316positive regulation of intracellular protein transport3.04e-021.00e+005.0171118
GO:0030532small nuclear ribonucleoprotein complex3.04e-021.00e+005.0171118
GO:0000139Golgi membrane3.20e-021.00e+002.10037408
GO:0007088regulation of mitosis3.21e-021.00e+004.9391119
GO:0010881regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion3.21e-021.00e+004.9391119
GO:2000134negative regulation of G1/S transition of mitotic cell cycle3.38e-021.00e+004.8651120
GO:0090398cellular senescence3.38e-021.00e+004.8651120
GO:0030544Hsp70 protein binding3.38e-021.00e+004.8651120
GO:0043473pigmentation3.38e-021.00e+004.8651220
GO:0015035protein disulfide oxidoreductase activity3.54e-021.00e+004.7951121
GO:0043034costamere3.54e-021.00e+004.7951121
GO:0046847filopodium assembly3.54e-021.00e+004.7951121
GO:0045211postsynaptic membrane3.68e-021.00e+002.71923177
GO:0007220Notch receptor processing3.71e-021.00e+004.7281222
GO:0005790smooth endoplasmic reticulum3.71e-021.00e+004.7281122
GO:0031435mitogen-activated protein kinase kinase kinase binding3.71e-021.00e+004.7281122
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle3.71e-021.00e+004.7281122
GO:0030863cortical cytoskeleton3.71e-021.00e+004.7281122
GO:0031625ubiquitin protein ligase binding3.79e-021.00e+002.69524180
GO:1900026positive regulation of substrate adhesion-dependent cell spreading3.87e-021.00e+004.6641123
GO:0051491positive regulation of filopodium assembly3.87e-021.00e+004.6641223
GO:0002040sprouting angiogenesis3.87e-021.00e+004.6641123
GO:0045879negative regulation of smoothened signaling pathway3.87e-021.00e+004.6641123
GO:0051017actin filament bundle assembly3.87e-021.00e+004.6641123
GO:0008060ARF GTPase activator activity3.87e-021.00e+004.6641123
GO:0001892embryonic placenta development3.87e-021.00e+004.6641123
GO:0051297centrosome organization3.87e-021.00e+004.6641223
GO:0043044ATP-dependent chromatin remodeling3.87e-021.00e+004.6641123
GO:0008135translation factor activity, nucleic acid binding4.04e-021.00e+004.6021424
GO:0005761mitochondrial ribosome4.04e-021.00e+004.6021124
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress4.04e-021.00e+004.6021124
GO:0007163establishment or maintenance of cell polarity4.04e-021.00e+004.6021224
GO:0046329negative regulation of JNK cascade4.04e-021.00e+004.6021124
GO:0043547positive regulation of GTPase activity4.18e-021.00e+002.61724190
GO:0032781positive regulation of ATPase activity4.20e-021.00e+004.5431125
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway4.20e-021.00e+004.5431225
GO:0007173epidermal growth factor receptor signaling pathway4.22e-021.00e+002.61025191
GO:0045931positive regulation of mitotic cell cycle4.37e-021.00e+004.4871226
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia4.37e-021.00e+004.4871226
GO:0045214sarcomere organization4.37e-021.00e+004.4871126
GO:0045859regulation of protein kinase activity4.37e-021.00e+004.4871126
GO:0005978glycogen biosynthetic process4.37e-021.00e+004.4871226
GO:0048589developmental growth4.37e-021.00e+004.4871126
GO:0001707mesoderm formation4.37e-021.00e+004.4871126
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity4.37e-021.00e+004.4871226
GO:0071556integral component of lumenal side of endoplasmic reticulum membrane4.37e-021.00e+004.4871126
GO:0051149positive regulation of muscle cell differentiation4.53e-021.00e+004.4321227
GO:0032720negative regulation of tumor necrosis factor production4.53e-021.00e+004.4321127
GO:0007616long-term memory4.53e-021.00e+004.4321127
GO:0005083small GTPase regulator activity4.53e-021.00e+004.4321127
GO:0031424keratinization4.53e-021.00e+004.4321127
GO:0048565digestive tract development4.53e-021.00e+004.4321127
GO:0031069hair follicle morphogenesis4.53e-021.00e+004.4321127
GO:0032467positive regulation of cytokinesis4.70e-021.00e+004.3801128
GO:0031492nucleosomal DNA binding4.70e-021.00e+004.3801128
GO:0019894kinesin binding4.70e-021.00e+004.3801128
GO:0005875microtubule associated complex4.70e-021.00e+004.3801128
GO:0045597positive regulation of cell differentiation4.70e-021.00e+004.3801128
GO:0007017microtubule-based process4.70e-021.00e+004.3801228
GO:0045944positive regulation of transcription from RNA polymerase II promoter4.80e-021.00e+001.524411811
GO:0031252cell leading edge4.86e-021.00e+004.3291329
GO:0003730mRNA 3'-UTR binding4.86e-021.00e+004.3291129
GO:0034605cellular response to heat4.86e-021.00e+004.3291129
GO:0072686mitotic spindle4.86e-021.00e+004.3291129
GO:0010977negative regulation of neuron projection development5.03e-021.00e+004.2801230
GO:0007346regulation of mitotic cell cycle5.03e-021.00e+004.2801330
GO:0031647regulation of protein stability5.03e-021.00e+004.2801130
GO:0002027regulation of heart rate5.03e-021.00e+004.2801230
GO:0040018positive regulation of multicellular organism growth5.03e-021.00e+004.2801130
GO:0010494cytoplasmic stress granule5.03e-021.00e+004.2801230
GO:0061077chaperone-mediated protein folding5.19e-021.00e+004.2331131
GO:0007093mitotic cell cycle checkpoint5.19e-021.00e+004.2331231
GO:0032480negative regulation of type I interferon production5.35e-021.00e+004.1871232
GO:0070830tight junction assembly5.51e-021.00e+004.1431133
GO:0016071mRNA metabolic process5.57e-021.00e+002.386229223
GO:0001569patterning of blood vessels5.68e-021.00e+004.1001134
GO:0007611learning or memory5.68e-021.00e+004.1001234
GO:0042692muscle cell differentiation5.68e-021.00e+004.1001234
GO:0048666neuron development5.84e-021.00e+004.0581135
GO:0071333cellular response to glucose stimulus5.84e-021.00e+004.0581235
GO:0009725response to hormone5.84e-021.00e+004.0581135
GO:0048471perinuclear region of cytoplasm5.93e-021.00e+001.74139523
GO:0007067mitotic nuclear division5.93e-021.00e+002.33527231
GO:0051402neuron apoptotic process6.00e-021.00e+004.0171136
GO:0030433ER-associated ubiquitin-dependent protein catabolic process6.00e-021.00e+004.0171136
GO:0001895retina homeostasis6.00e-021.00e+004.0171136
GO:0001102RNA polymerase II activating transcription factor binding6.16e-021.00e+003.9781137
GO:0051084'de novo' posttranslational protein folding6.16e-021.00e+003.9781237
GO:0005791rough endoplasmic reticulum6.16e-021.00e+003.9781137
GO:0001568blood vessel development6.32e-021.00e+003.9391238
GO:0070527platelet aggregation6.32e-021.00e+003.9391138
GO:0050681androgen receptor binding6.32e-021.00e+003.9391238
GO:0030049muscle filament sliding6.32e-021.00e+003.9391238
GO:0045740positive regulation of DNA replication6.32e-021.00e+003.9391138
GO:0030425dendrite6.34e-021.00e+002.28023240
GO:0016032viral process6.40e-021.00e+001.695337540
GO:0031490chromatin DNA binding6.48e-021.00e+003.9021139
GO:0060048cardiac muscle contraction6.48e-021.00e+003.9021139
GO:0001933negative regulation of protein phosphorylation6.48e-021.00e+003.9021139
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription6.65e-021.00e+003.8651140
GO:0016070RNA metabolic process6.67e-021.00e+002.239229247
GO:0051117ATPase binding6.81e-021.00e+003.8301241
GO:0008307structural constituent of muscle6.81e-021.00e+003.8301141
GO:0017148negative regulation of translation6.81e-021.00e+003.8301141
GO:0030521androgen receptor signaling pathway6.81e-021.00e+003.8301341
GO:0050885neuromuscular process controlling balance6.81e-021.00e+003.8301141
GO:0007249I-kappaB kinase/NF-kappaB signaling6.81e-021.00e+003.8301441
GO:0021987cerebral cortex development6.97e-021.00e+003.7951142
GO:0030155regulation of cell adhesion6.97e-021.00e+003.7951142
GO:0035914skeletal muscle cell differentiation6.97e-021.00e+003.7951142
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway7.13e-021.00e+003.7611243
GO:0005871kinesin complex7.29e-021.00e+003.7281144
GO:0050896response to stimulus7.29e-021.00e+003.7281144
GO:0016328lateral plasma membrane7.60e-021.00e+003.6641346
GO:0043525positive regulation of neuron apoptotic process7.60e-021.00e+003.6641246
GO:0001047core promoter binding7.60e-021.00e+003.6641146
GO:0043065positive regulation of apoptotic process7.98e-021.00e+002.08926274
GO:0001947heart looping8.08e-021.00e+003.5721149
GO:0003743translation initiation factor activity8.08e-021.00e+003.5721549
GO:0034097response to cytokine8.24e-021.00e+003.5431150
GO:0001948glycoprotein binding8.24e-021.00e+003.5431250
GO:0007254JNK cascade8.40e-021.00e+003.5151351
GO:0003684damaged DNA binding8.40e-021.00e+003.5151251
GO:0045732positive regulation of protein catabolic process8.40e-021.00e+003.5151151
GO:0005783endoplasmic reticulum8.53e-021.00e+001.51936610
GO:0045454cell redox homeostasis8.55e-021.00e+003.4871152
GO:0034976response to endoplasmic reticulum stress8.55e-021.00e+003.4871152
GO:0016042lipid catabolic process8.55e-021.00e+003.4871252
GO:0006952defense response8.71e-021.00e+003.4591153
GO:0045087innate immune response8.73e-021.00e+001.505311616
GO:0030666endocytic vesicle membrane8.87e-021.00e+003.4321254
GO:0051403stress-activated MAPK cascade8.87e-021.00e+003.4321454
GO:0019900kinase binding8.87e-021.00e+003.4321354
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding8.87e-021.00e+003.4321154
GO:0050680negative regulation of epithelial cell proliferation8.87e-021.00e+003.4321154
GO:0000226microtubule cytoskeleton organization9.03e-021.00e+003.4061155
GO:0046330positive regulation of JNK cascade9.03e-021.00e+003.4061155
GO:0006888ER to Golgi vesicle-mediated transport9.03e-021.00e+003.4061155
GO:0000932cytoplasmic mRNA processing body9.18e-021.00e+003.3801156
GO:0016197endosomal transport9.49e-021.00e+003.3291358
GO:0051087chaperone binding9.65e-021.00e+003.3041159
GO:0045216cell-cell junction organization9.65e-021.00e+003.3041259
GO:0005840ribosome9.65e-021.00e+003.30411059
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity9.65e-021.00e+003.3041159
GO:0010976positive regulation of neuron projection development9.81e-021.00e+003.2801260
GO:0005794Golgi apparatus9.88e-021.00e+001.42838650
GO:0005856cytoskeleton9.90e-021.00e+001.90626311
GO:0032481positive regulation of type I interferon production9.96e-021.00e+003.2561361
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity9.96e-021.00e+003.2561161
GO:0033138positive regulation of peptidyl-serine phosphorylation9.96e-021.00e+003.2561161
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.01e-011.00e+003.2331162
GO:0000776kinetochore1.03e-011.00e+003.2101363
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.04e-011.00e+003.1871264
GO:0019901protein kinase binding1.04e-011.00e+001.86529320
GO:0010467gene expression1.05e-011.00e+001.386336669
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.06e-011.00e+003.1651665
GO:0034146toll-like receptor 5 signaling pathway1.06e-011.00e+003.1651565
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.06e-011.00e+003.1651665
GO:0034166toll-like receptor 10 signaling pathway1.06e-011.00e+003.1651565
GO:0006469negative regulation of protein kinase activity1.06e-011.00e+003.1651165
GO:0071260cellular response to mechanical stimulus1.07e-011.00e+003.1431366
GO:0009636response to toxic substance1.07e-011.00e+003.1431166
GO:0007411axon guidance1.08e-011.00e+001.83423327
GO:0031295T cell costimulation1.09e-011.00e+003.1211367
GO:0030141secretory granule1.09e-011.00e+003.1211267
GO:0006338chromatin remodeling1.10e-011.00e+003.1001268
GO:0045666positive regulation of neuron differentiation1.10e-011.00e+003.1001168
GO:0050790regulation of catalytic activity1.12e-011.00e+003.0791169
GO:0003682chromatin binding1.12e-011.00e+001.80324334
GO:0006887exocytosis1.12e-011.00e+003.0791169
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.13e-011.00e+003.0581870
GO:0035264multicellular organism growth1.13e-011.00e+003.0581170
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway1.15e-011.00e+003.0371571
GO:0034329cell junction assembly1.15e-011.00e+003.0371271
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway1.15e-011.00e+003.0371571
GO:0042383sarcolemma1.15e-011.00e+003.0371271
GO:0034162toll-like receptor 9 signaling pathway1.17e-011.00e+003.0171572
GO:0034134toll-like receptor 2 signaling pathway1.18e-011.00e+002.9971573
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.18e-011.00e+002.9971673
GO:0000785chromatin1.18e-011.00e+002.9971273
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.20e-011.00e+002.9781874
GO:0005085guanyl-nucleotide exchange factor activity1.20e-011.00e+002.9781174
GO:0007265Ras protein signal transduction1.21e-011.00e+002.9581375
GO:0060070canonical Wnt signaling pathway1.21e-011.00e+002.9581275
GO:0003723RNA binding1.23e-011.00e+001.715210355
GO:0035666TRIF-dependent toll-like receptor signaling pathway1.23e-011.00e+002.9391576
GO:0044325ion channel binding1.24e-011.00e+002.9201377
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.24e-011.00e+002.9201677
GO:0008584male gonad development1.24e-011.00e+002.9201177
GO:0015031protein transport1.24e-011.00e+001.70724357
GO:0030054cell junction1.24e-011.00e+001.71124356
GO:0002756MyD88-independent toll-like receptor signaling pathway1.26e-011.00e+002.9021578
GO:0017137Rab GTPase binding1.26e-011.00e+002.9021178
GO:0071013catalytic step 2 spliceosome1.27e-011.00e+002.8831179
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.27e-011.00e+002.8831879
GO:0010629negative regulation of gene expression1.29e-011.00e+002.8651280
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.29e-011.00e+002.8651580
GO:0034138toll-like receptor 3 signaling pathway1.29e-011.00e+002.8651580
GO:0006351transcription, DNA-templated1.30e-011.00e+000.8795171585
GO:0045177apical part of cell1.32e-011.00e+002.8301182
GO:0005925focal adhesion1.32e-011.00e+001.656223370
GO:0030336negative regulation of cell migration1.33e-011.00e+002.8121283
GO:0007517muscle organ development1.33e-011.00e+002.8121183
GO:0043197dendritic spine1.33e-011.00e+002.8121283
GO:0003700sequence-specific DNA binding transcription factor activity1.35e-011.00e+001.22539748
GO:0005179hormone activity1.35e-011.00e+002.7951184
GO:0047485protein N-terminus binding1.38e-011.00e+002.7611186
GO:0007160cell-matrix adhesion1.41e-011.00e+002.7281188
GO:0050852T cell receptor signaling pathway1.41e-011.00e+002.7281288
GO:0000187activation of MAPK activity1.44e-011.00e+002.6951390
GO:0000922spindle pole1.45e-011.00e+002.6791591
GO:0018279protein N-linked glycosylation via asparagine1.45e-011.00e+002.6791191
GO:0006928cellular component movement1.47e-011.00e+002.6641492
GO:0016363nuclear matrix1.47e-011.00e+002.6641492
GO:0016605PML body1.47e-011.00e+002.6641292
GO:0042470melanosome1.47e-011.00e+002.6641292
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity1.48e-011.00e+002.6481193
GO:0051082unfolded protein binding1.51e-011.00e+002.6171195
GO:0034142toll-like receptor 4 signaling pathway1.52e-011.00e+002.6021596
GO:0006364rRNA processing1.52e-011.00e+002.6021896
GO:0030426growth cone1.54e-011.00e+002.5871397
GO:0071456cellular response to hypoxia1.55e-011.00e+002.5721398
GO:0005730nucleolus1.56e-011.00e+000.7915361684
GO:0004888transmembrane signaling receptor activity1.63e-011.00e+002.50111103
GO:0005096GTPase activator activity1.70e-011.00e+002.43213108
GO:0002224toll-like receptor signaling pathway1.71e-011.00e+002.41915109
GO:0030496midbody1.71e-011.00e+002.41914109
GO:0005938cell cortex1.71e-011.00e+002.41911109
GO:0005815microtubule organizing center1.73e-011.00e+002.40614110
GO:0015630microtubule cytoskeleton1.75e-011.00e+002.38014112
GO:0030529ribonucleoprotein complex1.78e-011.00e+002.35418114
GO:0005819spindle1.78e-011.00e+002.35414114
GO:0005634nucleus1.78e-011.00e+000.40911664828
GO:0072562blood microparticle1.81e-011.00e+002.32911116
GO:0097190apoptotic signaling pathway1.81e-011.00e+002.32913116
GO:0000209protein polyubiquitination1.81e-011.00e+002.32917116
GO:0005802trans-Golgi network1.81e-011.00e+002.32912116
GO:0005635nuclear envelope1.81e-011.00e+002.32912116
GO:0006006glucose metabolic process1.85e-011.00e+002.29214119
GO:0007596blood coagulation1.89e-011.00e+001.32925464
GO:0032496response to lipopolysaccharide1.90e-011.00e+002.25611122
GO:0016192vesicle-mediated transport1.90e-011.00e+002.25611122
GO:0006325chromatin organization1.91e-011.00e+002.24512123
GO:0051056regulation of small GTPase mediated signal transduction1.91e-011.00e+002.24513123
GO:0007568aging1.91e-011.00e+002.24512123
GO:0051092positive regulation of NF-kappaB transcription factor activity1.94e-011.00e+002.22113125
GO:0007219Notch signaling pathway1.94e-011.00e+002.22114125
GO:0007050cell cycle arrest1.95e-011.00e+002.21012126
GO:0006511ubiquitin-dependent protein catabolic process1.97e-011.00e+002.19813127
GO:0008201heparin binding1.97e-011.00e+002.19811127
GO:0005886plasma membrane2.01e-011.00e+000.5267242834
GO:0007179transforming growth factor beta receptor signaling pathway2.01e-011.00e+002.16514130
GO:0046983protein dimerization activity2.02e-011.00e+002.15413131
GO:0042802identical protein binding2.06e-011.00e+001.24824491
GO:0007507heart development2.16e-011.00e+002.04811141
GO:0005911cell-cell junction2.17e-011.00e+002.03712142
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling2.25e-011.00e+001.97813148
GO:0010628positive regulation of gene expression2.27e-011.00e+001.96814149
GO:0008017microtubule binding2.28e-011.00e+001.95812150
GO:0001666response to hypoxia2.28e-011.00e+001.95811150
GO:0051260protein homooligomerization2.28e-011.00e+001.95812150
GO:0030246carbohydrate binding2.29e-011.00e+001.94911151
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription2.29e-011.00e+001.94912151
GO:0010008endosome membrane2.37e-011.00e+001.89212157
GO:0008543fibroblast growth factor receptor signaling pathway2.40e-011.00e+001.87413159
GO:0043005neuron projection2.43e-011.00e+001.85616161
GO:0045121membrane raft2.43e-011.00e+001.85613161
GO:0000398mRNA splicing, via spliceosome2.48e-011.00e+001.82112165
GO:0034220ion transmembrane transport2.50e-011.00e+001.80312167
GO:0007601visual perception2.52e-011.00e+001.79511168
GO:0038095Fc-epsilon receptor signaling pathway2.56e-011.00e+001.76913171
GO:0016607nuclear speck2.61e-011.00e+001.73612175
GO:0031965nuclear membrane2.62e-011.00e+001.72812176
GO:0007049cell cycle2.63e-011.00e+001.71914177
GO:0000122negative regulation of transcription from RNA polymerase II promoter2.68e-011.00e+000.98529589
GO:0005509calcium ion binding2.68e-011.00e+000.98524589
GO:0043687post-translational protein modification2.68e-011.00e+001.68711181
GO:0015629actin cytoskeleton2.71e-011.00e+001.67113183
GO:0006367transcription initiation from RNA polymerase II promoter2.72e-011.00e+001.66415184
GO:0042803protein homodimerization activity2.86e-011.00e+000.91824617
GO:0005654nucleoplasm2.89e-011.00e+000.6753261095
GO:0003924GTPase activity2.96e-011.00e+001.52216203
GO:0030168platelet activation2.98e-011.00e+001.50814205
GO:0001701in utero embryonic development3.04e-011.00e+001.47312210
GO:0006184GTP catabolic process3.16e-011.00e+001.40616220
GO:0019221cytokine-mediated signaling pathway3.28e-011.00e+001.34215230
GO:0003713transcription coactivator activity3.39e-011.00e+001.28616239
GO:0007399nervous system development3.45e-011.00e+001.25011245
GO:0006281DNA repair3.67e-011.00e+001.14315264
GO:0000166nucleotide binding3.76e-011.00e+001.10012272
GO:0048011neurotrophin TRK receptor signaling pathway3.77e-011.00e+001.09415273
GO:0005975carbohydrate metabolic process3.78e-011.00e+001.08913274
GO:0003779actin binding3.79e-011.00e+001.08413275
GO:0007283spermatogenesis3.80e-011.00e+001.07912276
GO:0007264small GTPase mediated signal transduction3.95e-011.00e+001.00717290
GO:0030198extracellular matrix organization4.00e-011.00e+000.98311295
GO:0003677DNA binding4.12e-011.00e+000.3723141351
GO:0030154cell differentiation4.31e-011.00e+000.84313325
GO:0005525GTP binding4.34e-011.00e+000.83016328
GO:0043231intracellular membrane-bounded organelle4.38e-011.00e+000.81213332
GO:0007268synaptic transmission4.58e-011.00e+000.72411353
GO:0009986cell surface5.20e-011.00e+000.46611422
GO:0045892negative regulation of transcription, DNA-templated5.22e-011.00e+000.45912424
GO:0006366transcription from RNA polymerase II promoter5.23e-011.00e+000.45613425
GO:0005615extracellular space5.24e-011.00e+000.207231010
GO:0043066negative regulation of apoptotic process5.29e-011.00e+000.429114433
GO:0006468protein phosphorylation5.57e-011.00e+000.32016467
GO:0055114oxidation-reduction process5.68e-011.00e+000.27712481
GO:0045893positive regulation of transcription, DNA-templated5.72e-011.00e+000.25918487
GO:0006355regulation of transcription, DNA-templated5.74e-011.00e+000.0792101104
GO:0055085transmembrane transport5.92e-011.00e+000.18113514
GO:0006915apoptotic process6.31e-011.00e+000.03019571
GO:0005789endoplasmic reticulum membrane6.72e-011.00e+00-0.12613636
GO:0046872metal ion binding7.30e-011.00e+00-0.3302141465
GO:0007165signal transduction8.14e-011.00e+00-0.70517950
GO:0005887integral component of plasma membrane8.17e-011.00e+00-0.72112961
GO:0008270zinc ion binding8.50e-011.00e+00-0.872171067
GO:0044281small molecule metabolic process9.01e-011.00e+00-1.1521161295
GO:0005524ATP binding9.12e-011.00e+00-1.2161191354
GO:0016021integral component of membrane9.90e-011.00e+00-2.091142483