meta-int-snw-6210

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-60 tai-screen-luciferase 4.243 1.88e-19 3.43e-03 4.71e-03 12 5
int-snw-6210 tai-screen-luciferase 7.555 1.96e-202 4.38e-11 4.46e-05 14 13
reg-snw-1121 tai-screen-luciferase 4.707 1.91e-24 5.19e-04 8.44e-04 5 3
reg-snw-821 tai-screen-luciferase 4.344 1.76e-20 2.34e-03 3.35e-03 11 4
reg-snw-51164 tai-screen-luciferase 4.586 4.41e-23 8.78e-04 1.37e-03 6 4
reg-snw-57120 tai-screen-luciferase 4.450 1.33e-21 1.54e-03 2.29e-03 12 6
tai-screen-luciferase-meta-int-snw-6210 subnetwork

Genes (35)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS8 6202 33-5.5457.555234--
CHMP2A 27243 33-9.0377.55541YesYes
DMD 1756 15-4.3384.24353--
COPA 1314 48-9.3955.672340YesYes
PAFAH1B1 5048 18-2.5834.58655Yes-
TNFRSF8 943 19-4.1064.45015--
CUL4B 8450 21-2.8095.269142--
HSF1 3297 46-4.1795.027209-Yes
ARFGEF1 10565 13-2.7224.34415--
CANX 821 17-1.9594.50465--
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
RB1 5925 21-2.0854.707351--
EIF2S2 8894 31-4.3205.672103Yes-
CHM 1121 13-0.4834.7072--
CDC42 998 44-6.9604.707276YesYes
RPS11 6205 44-6.5887.555175Yes-
DCTN4 51164 13-1.8824.58619--
MRPS12 6183 35-5.4215.516341Yes-
SERBP1 26135 35-4.6125.516106-Yes
RPS13 6207 43-6.5897.555174Yes-
CDC5L 988 34-3.4195.672155--
HES4 57801 19-4.1534.45010--
GOPC 57120 191.7494.45068--
CAPRIN1 4076 14-2.2264.68842--
RPS24 6229 46-7.0348.389217Yes-
RPS9 6203 45-7.1277.555140Yes-
RPS4X 6191 44-6.7477.555263Yes-
COPZ1 22818 48-8.3019.06313YesYes
DNAJC10 54431 13-2.3494.34411--
RPS15A 6210 36-5.4137.555177Yes-
RPS27A 6233 45-5.6318.389344Yes-
SRF 6722 151.9944.24323--
ACTB 60 15-1.7164.24323--
ARCN1 372 48-8.2329.063118YesYes

Interactions (84)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
TNFRSF8 943 RB1 5925 pd < reg.pazar.txt: no annot
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
PAFAH1B1 5048 ARFGEF1 10565 pd > reg.ITFP.txt: no annot
ACTB 60 RPS4X 6191 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS11 6205 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CANX 821 pd < reg.ITFP.txt: no annot
COPA 1314 RB1 5925 pd <> reg.ITFP.txt: no annot
HSF1 3297 SRF 6722 pd <> reg.ITFP.txt: no annot
HSF1 3297 SRF 6722 pp -- int.Yu: muscle
COPA 1314 DCTN4 51164 pd > reg.ITFP.txt: no annot
CDC5L 988 CUL4B 8450 pd <> reg.ITFP.txt: no annot
ACTB 60 RPS8 6202 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPS9 6203 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RB1 5925 GOPC 57120 pd > reg.ITFP.txt: no annot
CANX 821 ARFGEF1 10565 pd > reg.ITFP.txt: no annot
CANX 821 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
RB1 5925 HES4 57801 pd > reg.pazar.txt: no annot
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPS13 6207 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
CHM 1121 COPA 1314 pd < reg.ITFP.txt: no annot
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RB1 5925 SERBP1 26135 pd > reg.pazar.txt: no annot
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
ACTB 60 MRPS12 6183 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPS24 6229 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS27A 6233 ARFGEF1 10565 pp -- int.I2D: YeastLow
RPS9 6203 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
CUL4B 8450 GOPC 57120 pd > reg.ITFP.txt: no annot
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
PAFAH1B1 5048 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
PAFAH1B1 5048 GOPC 57120 pd > reg.ITFP.txt: no annot
CAPRIN1 4076 CKAP5 9793 pd < reg.ITFP.txt: no annot
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CDC42 998 ARFGEF1 10565 pp -- int.I2D: IntAct, SOURAV_MAPK_LOW
ACTB 60 RB1 5925 pd < reg.ITFP.txt: no annot
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
ACTB 60 COPA 1314 pd < reg.ITFP.txt: no annot
ACTB 60 COPA 1314 pp -- int.I2D: BioGrid_Yeast
CAPRIN1 4076 CUL4B 8450 pd < reg.ITFP.txt: no annot
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
PAFAH1B1 5048 DCTN4 51164 pd > reg.ITFP.txt: no annot
DMD 1756 SRF 6722 pd < reg.pazar.txt: no annot;
reg.TRANSFAC.txt: no annot
CANX 821 RB1 5925 pd <> reg.ITFP.txt: no annot
ACTB 60 PAFAH1B1 5048 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
CANX 821 MRPS12 6183 pp -- int.I2D: BioGrid_Yeast
CDC42 998 GOPC 57120 pp -- int.I2D: BioGrid
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
CANX 821 COPA 1314 pd <> reg.ITFP.txt: no annot
COPA 1314 CAPRIN1 4076 pd > reg.ITFP.txt: no annot
ACTB 60 ARCN1 372 pp -- int.I2D: BioGrid_Yeast
ACTB 60 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
CUL4B 8450 DNAJC10 54431 pd > reg.ITFP.txt: no annot
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RB1 5925 DCTN4 51164 pd > reg.ITFP.txt: no annot
COPA 1314 GOPC 57120 pd > reg.ITFP.txt: no annot
CDC5L 988 GOPC 57120 pd > reg.ITFP.txt: no annot
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
COPA 1314 CUL4B 8450 pd <> reg.ITFP.txt: no annot
CDC5L 988 EIF2S2 8894 pd > reg.ITFP.txt: no annot
CHM 1121 RB1 5925 pd < reg.ITFP.txt: no annot
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
CANX 821 DCTN4 51164 pd > reg.ITFP.txt: no annot
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
CDC42 998 RB1 5925 pd < reg.pazar.txt: no annot
CANX 821 DNAJC10 54431 pd > reg.ITFP.txt: no annot
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RPS8 6202 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS27A 6233 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
ACTB 60 SRF 6722 pd < reg.pazar.txt: no annot;
reg.oreganno.txt: no annot
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
COPA 1314 PAFAH1B1 5048 pd <> reg.ITFP.txt: no annot

Related GO terms (597)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit1.11e-141.81e-106.58082139
GO:0019058viral life cycle1.89e-123.08e-085.190925115
GO:0019083viral transcription5.45e-128.90e-085.52582281
GO:0006413translational initiation6.20e-121.01e-075.002927131
GO:0006415translational termination9.82e-121.60e-075.42282287
GO:0003735structural constituent of ribosome1.21e-111.97e-074.896924141
GO:0006414translational elongation1.70e-112.77e-075.32682293
GO:0016020membrane2.31e-113.77e-072.41720481746
GO:0005829cytosol3.53e-115.76e-072.06623742562
GO:0006614SRP-dependent cotranslational protein targeting to membrane4.22e-116.89e-075.165822104
GO:0006412translation4.24e-116.91e-074.3111029235
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay8.89e-111.45e-065.032822114
GO:0044822poly(A) RNA binding1.67e-092.73e-052.69815421078
GO:0044267cellular protein metabolic process3.86e-096.30e-053.3731129495
GO:0048205COPI coating of Golgi vesicle1.25e-082.04e-047.1654613
GO:0030126COPI vesicle coat1.25e-082.04e-047.1654613
GO:0016071mRNA metabolic process1.84e-083.00e-044.064829223
GO:0061024membrane organization2.16e-083.53e-044.483711146
GO:0016070RNA metabolic process4.06e-086.63e-043.917829247
GO:0015935small ribosomal subunit4.13e-086.75e-046.7784917
GO:0016032viral process1.26e-072.06e-033.1101037540
GO:0005840ribosome1.55e-072.53e-035.30451059
GO:0006890retrograde vesicle-mediated transport, Golgi to ER2.17e-073.54e-036.2214625
GO:0010467gene expression8.38e-061.37e-012.649936669
GO:0005925focal adhesion1.13e-051.85e-013.141723370
GO:0036464cytoplasmic ribonucleoprotein granule1.35e-052.21e-015.9913522
GO:0070062extracellular vesicular exosome2.09e-053.41e-011.56816512516
GO:0019843rRNA binding2.55e-054.16e-015.6953427
GO:0043234protein complex3.80e-056.20e-013.22169300
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.45e-057.26e-017.543235
GO:0007097nuclear migration9.32e-051.00e+007.058227
GO:0030529ribonucleoprotein complex1.00e-041.00e+004.03248114
GO:0090136epithelial cell-cell adhesion1.59e-041.00e+006.695229
GO:0005737cytoplasm4.91e-041.00e+001.07818653976
GO:0006886intracellular protein transport4.94e-041.00e+003.43146173
GO:0050998nitric-oxide synthase binding5.26e-041.00e+005.8652316
GO:0006891intra-Golgi vesicle-mediated transport5.95e-041.00e+005.7782317
GO:0017022myosin binding6.69e-041.00e+005.6952218
GO:0009306protein secretion9.14e-041.00e+005.4732221
GO:0051219phosphoprotein binding2.13e-031.00e+004.8652432
GO:0030038contractile actin filament bundle assembly2.14e-031.00e+008.865111
GO:0045556positive regulation of TRAIL biosynthetic process2.14e-031.00e+008.865111
GO:0090287regulation of cellular response to growth factor stimulus2.14e-031.00e+008.865111
GO:0000235astral microtubule2.14e-031.00e+008.865111
GO:0090284positive regulation of protein glycosylation in Golgi2.14e-031.00e+008.865111
GO:0090230regulation of centromere complex assembly2.14e-031.00e+008.865111
GO:0043004cytoplasmic sequestering of CFTR protein2.14e-031.00e+008.865111
GO:0021691cerebellar Purkinje cell layer maturation2.14e-031.00e+008.865111
GO:0051660establishment of centrosome localization2.14e-031.00e+008.865111
GO:0034975protein folding in endoplasmic reticulum2.14e-031.00e+008.865111
GO:0046016positive regulation of transcription by glucose2.14e-031.00e+008.865111
GO:0046469platelet activating factor metabolic process2.14e-031.00e+008.865111
GO:0034332adherens junction organization2.69e-031.00e+004.6952436
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway2.69e-031.00e+004.6952336
GO:0000086G2/M transition of mitotic cell cycle3.11e-031.00e+003.35236137
GO:0021766hippocampus development3.15e-031.00e+004.5802339
GO:0034613cellular protein localization3.99e-031.00e+004.4062244
GO:0010256endomembrane system organization4.28e-031.00e+007.865112
GO:0071987WD40-repeat domain binding4.28e-031.00e+007.865112
GO:0060661submandibular salivary gland formation4.28e-031.00e+007.865112
GO:0036035osteoclast development4.28e-031.00e+007.865112
GO:0014819regulation of skeletal muscle contraction4.28e-031.00e+007.865112
GO:0086001cardiac muscle cell action potential4.28e-031.00e+007.865112
GO:0071338positive regulation of hair follicle cell proliferation4.28e-031.00e+007.865112
GO:0051081nuclear envelope disassembly4.28e-031.00e+007.865112
GO:0002176male germ cell proliferation4.28e-031.00e+007.865112
GO:0072422signal transduction involved in DNA damage checkpoint4.28e-031.00e+007.865112
GO:0090135actin filament branching4.28e-031.00e+007.865112
GO:0031134sister chromatid biorientation4.28e-031.00e+007.865112
GO:0010736serum response element binding4.28e-031.00e+007.865112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis4.28e-031.00e+007.865112
GO:0021762substantia nigra development4.36e-031.00e+004.3422246
GO:0008344adult locomotory behavior4.55e-031.00e+004.3112247
GO:0007030Golgi organization5.13e-031.00e+004.2212350
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding5.51e-031.00e+003.05834168
GO:0030175filopodium5.75e-031.00e+004.1372253
GO:0005515protein binding5.75e-031.00e+000.67721876127
GO:0030424axon5.88e-031.00e+003.02434172
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding6.42e-031.00e+007.280113
GO:0014809regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion6.42e-031.00e+007.280113
GO:0060947cardiac vascular smooth muscle cell differentiation6.42e-031.00e+007.280113
GO:0003161cardiac conduction system development6.42e-031.00e+007.280113
GO:0071459protein localization to chromosome, centromeric region6.42e-031.00e+007.280113
GO:1900222negative regulation of beta-amyloid clearance6.42e-031.00e+007.280113
GO:1901385regulation of voltage-gated calcium channel activity6.42e-031.00e+007.280113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle6.42e-031.00e+007.280113
GO:0045505dynein intermediate chain binding6.42e-031.00e+007.280113
GO:0051683establishment of Golgi localization6.42e-031.00e+007.280123
GO:0022028tangential migration from the subventricular zone to the olfactory bulb6.42e-031.00e+007.280113
GO:0016671oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor6.42e-031.00e+007.280113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity6.42e-031.00e+007.280113
GO:0033561regulation of water loss via skin6.42e-031.00e+007.280113
GO:0005850eukaryotic translation initiation factor 2 complex6.42e-031.00e+007.280113
GO:0034663endoplasmic reticulum chaperone complex6.42e-031.00e+007.280113
GO:1902083negative regulation of peptidyl-cysteine S-nitrosylation6.42e-031.00e+007.280123
GO:0021540corpus callosum morphogenesis6.42e-031.00e+007.280113
GO:0016197endosomal transport6.85e-031.00e+004.0072358
GO:0071922regulation of cohesin localization to chromatin8.55e-031.00e+006.865124
GO:0034191apolipoprotein A-I receptor binding8.55e-031.00e+006.865114
GO:0010669epithelial structure maintenance8.55e-031.00e+006.865114
GO:0060684epithelial-mesenchymal cell signaling8.55e-031.00e+006.865114
GO:0051835positive regulation of synapse structural plasticity8.55e-031.00e+006.865114
GO:0015036disulfide oxidoreductase activity8.55e-031.00e+006.865114
GO:0043550regulation of lipid kinase activity8.55e-031.00e+006.865114
GO:0016013syntrophin complex8.55e-031.00e+006.865124
GO:0090231regulation of spindle checkpoint8.55e-031.00e+006.865114
GO:0072384organelle transport along microtubule8.55e-031.00e+006.865124
GO:0003257positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation8.55e-031.00e+006.865114
GO:0048664neuron fate determination8.55e-031.00e+006.865114
GO:0010735positive regulation of transcription via serum response element binding8.55e-031.00e+006.865114
GO:0005968Rab-protein geranylgeranyltransferase complex8.55e-031.00e+006.865114
GO:0035189Rb-E2F complex8.55e-031.00e+006.865114
GO:0034088maintenance of mitotic sister chromatid cohesion8.55e-031.00e+006.865114
GO:0034349glial cell apoptotic process8.55e-031.00e+006.865114
GO:0000278mitotic cell cycle1.00e-021.00e+002.229416398
GO:0036336dendritic cell migration1.07e-021.00e+006.543115
GO:2000651positive regulation of sodium ion transmembrane transporter activity1.07e-021.00e+006.543115
GO:0035088establishment or maintenance of apical/basal cell polarity1.07e-021.00e+006.543115
GO:0048667cell morphogenesis involved in neuron differentiation1.07e-021.00e+006.543115
GO:1902188positive regulation of viral release from host cell1.07e-021.00e+006.543115
GO:0031256leading edge membrane1.07e-021.00e+006.543115
GO:0044233ER-mitochondrion membrane contact site1.07e-021.00e+006.543115
GO:0035912dorsal aorta morphogenesis1.07e-021.00e+006.543115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.07e-021.00e+006.543115
GO:0043043peptide biosynthetic process1.07e-021.00e+006.543115
GO:0031023microtubule organizing center organization1.07e-021.00e+006.543115
GO:0033119negative regulation of RNA splicing1.07e-021.00e+006.543125
GO:0004663Rab geranylgeranyltransferase activity1.07e-021.00e+006.543115
GO:0031175neuron projection development1.12e-021.00e+003.6362275
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.18e-021.00e+003.5982477
GO:0043353enucleate erythrocyte differentiation1.28e-021.00e+006.280116
GO:0007143female meiotic division1.28e-021.00e+006.280116
GO:0044458motile cilium assembly1.28e-021.00e+006.280116
GO:0045182translation regulator activity1.28e-021.00e+006.280126
GO:0051150regulation of smooth muscle cell differentiation1.28e-021.00e+006.280116
GO:0018344protein geranylgeranylation1.28e-021.00e+006.280116
GO:0060789hair follicle placode formation1.28e-021.00e+006.280116
GO:0008090retrograde axon cargo transport1.28e-021.00e+006.280116
GO:0048554positive regulation of metalloenzyme activity1.28e-021.00e+006.280116
GO:0050792regulation of viral process1.28e-021.00e+006.280116
GO:0045842positive regulation of mitotic metaphase/anaphase transition1.28e-021.00e+006.280116
GO:0001667ameboidal-type cell migration1.28e-021.00e+006.280116
GO:0000974Prp19 complex1.28e-021.00e+006.280116
GO:0030957Tat protein binding1.28e-021.00e+006.280116
GO:0034452dynactin binding1.28e-021.00e+006.280116
GO:0060261positive regulation of transcription initiation from RNA polymerase II promoter1.49e-021.00e+006.058117
GO:0006893Golgi to plasma membrane transport1.49e-021.00e+006.058117
GO:0060055angiogenesis involved in wound healing1.49e-021.00e+006.058117
GO:0060136embryonic process involved in female pregnancy1.49e-021.00e+006.058117
GO:0043497regulation of protein heterodimerization activity1.49e-021.00e+006.058117
GO:0050658RNA transport1.49e-021.00e+006.058117
GO:0003334keratinocyte development1.49e-021.00e+006.058117
GO:0051988regulation of attachment of spindle microtubules to kinetochore1.49e-021.00e+006.058117
GO:0070914UV-damage excision repair1.49e-021.00e+006.058117
GO:0001961positive regulation of cytokine-mediated signaling pathway1.49e-021.00e+006.058117
GO:0034101erythrocyte homeostasis1.49e-021.00e+006.058117
GO:0002162dystroglycan binding1.49e-021.00e+006.058117
GO:0030157pancreatic juice secretion1.49e-021.00e+006.058117
GO:0017145stem cell division1.49e-021.00e+006.058117
GO:0000930gamma-tubulin complex1.49e-021.00e+006.058117
GO:0034259negative regulation of Rho GTPase activity1.49e-021.00e+006.058117
GO:0008134transcription factor binding1.55e-021.00e+002.50835246
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II1.66e-021.00e+003.3422392
GO:0005200structural constituent of cytoskeleton1.69e-021.00e+003.3262693
GO:0043025neuronal cell body1.69e-021.00e+002.46135254
GO:0090009primitive streak formation1.70e-021.00e+005.865118
GO:0031512motile primary cilium1.70e-021.00e+005.865118
GO:0039702viral budding via host ESCRT complex1.70e-021.00e+005.865118
GO:0043589skin morphogenesis1.70e-021.00e+005.865118
GO:0007289spermatid nucleus differentiation1.70e-021.00e+005.865118
GO:0070688MLL5-L complex1.70e-021.00e+005.865118
GO:0005869dynactin complex1.70e-021.00e+005.865118
GO:0051489regulation of filopodium assembly1.70e-021.00e+005.865118
GO:0061003positive regulation of dendritic spine morphogenesis1.70e-021.00e+005.865118
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.73e-021.00e+003.3112794
GO:0001764neuron migration1.80e-021.00e+003.2802296
GO:0097284hepatocyte apoptotic process1.91e-021.00e+005.695119
GO:0000983RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity1.91e-021.00e+005.695119
GO:0000075cell cycle checkpoint1.91e-021.00e+005.695119
GO:0021895cerebral cortex neuron differentiation1.91e-021.00e+005.695119
GO:0030837negative regulation of actin filament polymerization1.91e-021.00e+005.695119
GO:0032319regulation of Rho GTPase activity1.91e-021.00e+005.695119
GO:0045059positive thymic T cell selection1.91e-021.00e+005.695119
GO:0034237protein kinase A regulatory subunit binding2.12e-021.00e+005.5431110
GO:0051787misfolded protein binding2.12e-021.00e+005.5431110
GO:0042535positive regulation of tumor necrosis factor biosynthetic process2.12e-021.00e+005.5431110
GO:0031274positive regulation of pseudopodium assembly2.12e-021.00e+005.5431210
GO:0001076RNA polymerase II transcription factor binding transcription factor activity2.12e-021.00e+005.5431110
GO:0090303positive regulation of wound healing2.12e-021.00e+005.5431110
GO:0061029eyelid development in camera-type eye2.12e-021.00e+005.5431110
GO:0001675acrosome assembly2.12e-021.00e+005.5431110
GO:0060218hematopoietic stem cell differentiation2.12e-021.00e+005.5431110
GO:0060047heart contraction2.12e-021.00e+005.5431110
GO:0014069postsynaptic density2.16e-021.00e+003.13723106
GO:0045502dynein binding2.33e-021.00e+005.4061111
GO:0045176apical protein localization2.33e-021.00e+005.4061111
GO:0017166vinculin binding2.33e-021.00e+005.4061111
GO:0042551neuron maturation2.33e-021.00e+005.4061111
GO:0045651positive regulation of macrophage differentiation2.33e-021.00e+005.4061111
GO:0045120pronucleus2.33e-021.00e+005.4061111
GO:0035518histone H2A monoubiquitination2.33e-021.00e+005.4061211
GO:0002011morphogenesis of an epithelial sheet2.33e-021.00e+005.4061111
GO:0021819layer formation in cerebral cortex2.33e-021.00e+005.4061111
GO:0007051spindle organization2.54e-021.00e+005.2801112
GO:0051146striated muscle cell differentiation2.54e-021.00e+005.2801212
GO:0042274ribosomal small subunit biogenesis2.54e-021.00e+005.2801612
GO:0043149stress fiber assembly2.54e-021.00e+005.2801212
GO:0019082viral protein processing2.54e-021.00e+005.2801212
GO:0030140trans-Golgi network transport vesicle2.54e-021.00e+005.2801112
GO:0072583clathrin-mediated endocytosis2.54e-021.00e+005.2801112
GO:0047496vesicle transport along microtubule2.54e-021.00e+005.2801112
GO:1903543positive regulation of exosomal secretion2.54e-021.00e+005.2801112
GO:0055003cardiac myofibril assembly2.54e-021.00e+005.2801112
GO:0042789mRNA transcription from RNA polymerase II promoter2.75e-021.00e+005.1651113
GO:0001671ATPase activator activity2.75e-021.00e+005.1651113
GO:0043488regulation of mRNA stability2.75e-021.00e+005.1651113
GO:0032479regulation of type I interferon production2.75e-021.00e+005.1651213
GO:0005662DNA replication factor A complex2.75e-021.00e+005.1651113
GO:1900087positive regulation of G1/S transition of mitotic cell cycle2.75e-021.00e+005.1651113
GO:0060314regulation of ryanodine-sensitive calcium-release channel activity2.75e-021.00e+005.1651113
GO:0035855megakaryocyte development2.75e-021.00e+005.1651113
GO:0035371microtubule plus-end2.96e-021.00e+005.0581114
GO:0031333negative regulation of protein complex assembly2.96e-021.00e+005.0581114
GO:0060292long term synaptic depression2.96e-021.00e+005.0581114
GO:0048488synaptic vesicle endocytosis2.96e-021.00e+005.0581114
GO:0035267NuA4 histone acetyltransferase complex2.96e-021.00e+005.0581214
GO:0031996thioesterase binding2.96e-021.00e+005.0581114
GO:0034185apolipoprotein binding2.96e-021.00e+005.0581114
GO:0030036actin cytoskeleton organization3.11e-021.00e+002.85423129
GO:0030131clathrin adaptor complex3.17e-021.00e+004.9581115
GO:0002042cell migration involved in sprouting angiogenesis3.17e-021.00e+004.9581115
GO:0030225macrophage differentiation3.17e-021.00e+004.9581115
GO:0016514SWI/SNF complex3.17e-021.00e+004.9581115
GO:0045987positive regulation of smooth muscle contraction3.17e-021.00e+004.9581115
GO:0045445myoblast differentiation3.17e-021.00e+004.9581115
GO:0048821erythrocyte development3.17e-021.00e+004.9581215
GO:0016010dystrophin-associated glycoprotein complex3.17e-021.00e+004.9581115
GO:0031369translation initiation factor binding3.17e-021.00e+004.9581215
GO:2000114regulation of establishment of cell polarity3.17e-021.00e+004.9581115
GO:0051233spindle midzone3.17e-021.00e+004.9581215
GO:0048854brain morphogenesis3.17e-021.00e+004.9581115
GO:0060347heart trabecula formation3.17e-021.00e+004.9581115
GO:0000790nuclear chromatin3.29e-021.00e+002.81022133
GO:0032839dendrite cytoplasm3.38e-021.00e+004.8651116
GO:0007405neuroblast proliferation3.38e-021.00e+004.8651116
GO:0032012regulation of ARF protein signal transduction3.38e-021.00e+004.8651116
GO:0019226transmission of nerve impulse3.38e-021.00e+004.8651116
GO:0000132establishment of mitotic spindle orientation3.38e-021.00e+004.8651216
GO:0042176regulation of protein catabolic process3.38e-021.00e+004.8651416
GO:0033137negative regulation of peptidyl-serine phosphorylation3.38e-021.00e+004.8651116
GO:0030220platelet formation3.38e-021.00e+004.8651116
GO:0043623cellular protein complex assembly3.38e-021.00e+004.8651116
GO:0046716muscle cell cellular homeostasis3.38e-021.00e+004.8651116
GO:0050775positive regulation of dendrite morphogenesis3.38e-021.00e+004.8651116
GO:0005813centrosome3.56e-021.00e+002.04539339
GO:0035255ionotropic glutamate receptor binding3.59e-021.00e+004.7781117
GO:0010880regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum3.59e-021.00e+004.7781117
GO:0075733intracellular transport of virus3.59e-021.00e+004.7781317
GO:0043274phospholipase binding3.59e-021.00e+004.7781117
GO:0019068virion assembly3.59e-021.00e+004.7781217
GO:0008306associative learning3.59e-021.00e+004.7781117
GO:0031527filopodium membrane3.59e-021.00e+004.7781117
GO:0001829trophectodermal cell differentiation3.59e-021.00e+004.7781117
GO:0030742GTP-dependent protein binding3.59e-021.00e+004.7781117
GO:0006612protein targeting to membrane3.79e-021.00e+004.6951218
GO:0045773positive regulation of axon extension3.79e-021.00e+004.6951118
GO:0005086ARF guanyl-nucleotide exchange factor activity3.79e-021.00e+004.6951118
GO:0090316positive regulation of intracellular protein transport3.79e-021.00e+004.6951118
GO:0030532small nuclear ribonucleoprotein complex3.79e-021.00e+004.6951118
GO:0007088regulation of mitosis4.00e-021.00e+004.6171119
GO:0003723RNA binding4.00e-021.00e+001.978310355
GO:0010881regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion4.00e-021.00e+004.6171119
GO:0006457protein folding4.05e-021.00e+002.64623149
GO:0015031protein transport4.06e-021.00e+001.97034357
GO:0000082G1/S transition of mitotic cell cycle4.10e-021.00e+002.636211150
GO:0042981regulation of apoptotic process4.15e-021.00e+002.62727151
GO:2000134negative regulation of G1/S transition of mitotic cell cycle4.21e-021.00e+004.5431120
GO:0090398cellular senescence4.21e-021.00e+004.5431120
GO:0030544Hsp70 protein binding4.21e-021.00e+004.5431120
GO:0043473pigmentation4.21e-021.00e+004.5431220
GO:0008285negative regulation of cell proliferation4.34e-021.00e+001.93033367
GO:0015035protein disulfide oxidoreductase activity4.41e-021.00e+004.4731121
GO:0043034costamere4.41e-021.00e+004.4731121
GO:0046847filopodium assembly4.41e-021.00e+004.4731121
GO:0005788endoplasmic reticulum lumen4.45e-021.00e+002.57122157
GO:0005198structural molecule activity4.55e-021.00e+002.55225159
GO:0007220Notch receptor processing4.62e-021.00e+004.4061222
GO:0005790smooth endoplasmic reticulum4.62e-021.00e+004.4061122
GO:0031435mitogen-activated protein kinase kinase kinase binding4.62e-021.00e+004.4061122
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle4.62e-021.00e+004.4061122
GO:0030863cortical cytoskeleton4.62e-021.00e+004.4061122
GO:1900026positive regulation of substrate adhesion-dependent cell spreading4.82e-021.00e+004.3421123
GO:0051491positive regulation of filopodium assembly4.82e-021.00e+004.3421223
GO:0045787positive regulation of cell cycle4.82e-021.00e+004.3421223
GO:0002040sprouting angiogenesis4.82e-021.00e+004.3421123
GO:0045879negative regulation of smoothened signaling pathway4.82e-021.00e+004.3421123
GO:0051017actin filament bundle assembly4.82e-021.00e+004.3421123
GO:0008060ARF GTPase activator activity4.82e-021.00e+004.3421123
GO:0001892embryonic placenta development4.82e-021.00e+004.3421123
GO:0051297centrosome organization4.82e-021.00e+004.3421223
GO:0043044ATP-dependent chromatin remodeling4.82e-021.00e+004.3421123
GO:0008135translation factor activity, nucleic acid binding5.03e-021.00e+004.2801424
GO:0005761mitochondrial ribosome5.03e-021.00e+004.2801124
GO:0070059intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress5.03e-021.00e+004.2801124
GO:0007163establishment or maintenance of cell polarity5.03e-021.00e+004.2801224
GO:0046329negative regulation of JNK cascade5.03e-021.00e+004.2801124
GO:0008284positive regulation of cell proliferation5.11e-021.00e+001.83537392
GO:0032781positive regulation of ATPase activity5.23e-021.00e+004.2211125
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway5.23e-021.00e+004.2211225
GO:0005844polysome5.23e-021.00e+004.2211225
GO:0045931positive regulation of mitotic cell cycle5.43e-021.00e+004.1651226
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia5.43e-021.00e+004.1651226
GO:0045214sarcomere organization5.43e-021.00e+004.1651126
GO:0045859regulation of protein kinase activity5.43e-021.00e+004.1651126
GO:0005978glycogen biosynthetic process5.43e-021.00e+004.1651226
GO:0048589developmental growth5.43e-021.00e+004.1651126
GO:0001707mesoderm formation5.43e-021.00e+004.1651126
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity5.43e-021.00e+004.1651226
GO:0071556integral component of lumenal side of endoplasmic reticulum membrane5.43e-021.00e+004.1651126
GO:0045211postsynaptic membrane5.51e-021.00e+002.39823177
GO:0000139Golgi membrane5.63e-021.00e+001.77837408
GO:0051149positive regulation of muscle cell differentiation5.64e-021.00e+004.1101227
GO:0032720negative regulation of tumor necrosis factor production5.64e-021.00e+004.1101127
GO:0007616long-term memory5.64e-021.00e+004.1101127
GO:0005083small GTPase regulator activity5.64e-021.00e+004.1101127
GO:0031424keratinization5.64e-021.00e+004.1101127
GO:0045184establishment of protein localization5.64e-021.00e+004.1101227
GO:0048565digestive tract development5.64e-021.00e+004.1101127
GO:0031069hair follicle morphogenesis5.64e-021.00e+004.1101127
GO:0031625ubiquitin protein ligase binding5.68e-021.00e+002.37324180
GO:0032467positive regulation of cytokinesis5.84e-021.00e+004.0581128
GO:0031492nucleosomal DNA binding5.84e-021.00e+004.0581128
GO:0019894kinesin binding5.84e-021.00e+004.0581128
GO:0005875microtubule associated complex5.84e-021.00e+004.0581128
GO:0045597positive regulation of cell differentiation5.84e-021.00e+004.0581128
GO:0007017microtubule-based process5.84e-021.00e+004.0581228
GO:0031252cell leading edge6.04e-021.00e+004.0071329
GO:0003730mRNA 3'-UTR binding6.04e-021.00e+004.0071129
GO:0034605cellular response to heat6.04e-021.00e+004.0071129
GO:0072686mitotic spindle6.04e-021.00e+004.0071129
GO:0010977negative regulation of neuron projection development6.24e-021.00e+003.9581230
GO:0007346regulation of mitotic cell cycle6.24e-021.00e+003.9581330
GO:0043547positive regulation of GTPase activity6.24e-021.00e+002.29524190
GO:0031647regulation of protein stability6.24e-021.00e+003.9581130
GO:0002027regulation of heart rate6.24e-021.00e+003.9581230
GO:0040018positive regulation of multicellular organism growth6.24e-021.00e+003.9581130
GO:0010494cytoplasmic stress granule6.24e-021.00e+003.9581230
GO:0007173epidermal growth factor receptor signaling pathway6.30e-021.00e+002.28825191
GO:0005730nucleolus6.32e-021.00e+000.9557361684
GO:0061077chaperone-mediated protein folding6.44e-021.00e+003.9111131
GO:0007093mitotic cell cycle checkpoint6.44e-021.00e+003.9111231
GO:0032480negative regulation of type I interferon production6.65e-021.00e+003.8651232
GO:0070830tight junction assembly6.85e-021.00e+003.8211133
GO:0001569patterning of blood vessels7.05e-021.00e+003.7781134
GO:0007611learning or memory7.05e-021.00e+003.7781234
GO:0042692muscle cell differentiation7.05e-021.00e+003.7781234
GO:0048666neuron development7.25e-021.00e+003.7361135
GO:0071333cellular response to glucose stimulus7.25e-021.00e+003.7361235
GO:0009725response to hormone7.25e-021.00e+003.7361135
GO:0051402neuron apoptotic process7.45e-021.00e+003.6951136
GO:0030433ER-associated ubiquitin-dependent protein catabolic process7.45e-021.00e+003.6951136
GO:0001895retina homeostasis7.45e-021.00e+003.6951136
GO:0001102RNA polymerase II activating transcription factor binding7.64e-021.00e+003.6561137
GO:0051084'de novo' posttranslational protein folding7.64e-021.00e+003.6561237
GO:0005791rough endoplasmic reticulum7.64e-021.00e+003.6561137
GO:0001568blood vessel development7.84e-021.00e+003.6171238
GO:0070527platelet aggregation7.84e-021.00e+003.6171138
GO:0050681androgen receptor binding7.84e-021.00e+003.6171238
GO:0030049muscle filament sliding7.84e-021.00e+003.6171238
GO:0045740positive regulation of DNA replication7.84e-021.00e+003.6171138
GO:0031490chromatin DNA binding8.04e-021.00e+003.5801139
GO:0060048cardiac muscle contraction8.04e-021.00e+003.5801139
GO:0001933negative regulation of protein phosphorylation8.04e-021.00e+003.5801139
GO:0001228RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription8.24e-021.00e+003.5431140
GO:0051117ATPase binding8.44e-021.00e+003.5081241
GO:0008307structural constituent of muscle8.44e-021.00e+003.5081141
GO:0017148negative regulation of translation8.44e-021.00e+003.5081141
GO:0030521androgen receptor signaling pathway8.44e-021.00e+003.5081341
GO:0050885neuromuscular process controlling balance8.44e-021.00e+003.5081141
GO:0007249I-kappaB kinase/NF-kappaB signaling8.44e-021.00e+003.5081441
GO:0021987cerebral cortex development8.63e-021.00e+003.4731142
GO:0030155regulation of cell adhesion8.63e-021.00e+003.4731142
GO:0035914skeletal muscle cell differentiation8.63e-021.00e+003.4731142
GO:0007067mitotic nuclear division8.75e-021.00e+002.01327231
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway8.83e-021.00e+003.4391243
GO:0005871kinesin complex9.02e-021.00e+003.4061144
GO:0050896response to stimulus9.02e-021.00e+003.4061144
GO:0030425dendrite9.34e-021.00e+001.95823240
GO:0045944positive regulation of transcription from RNA polymerase II promoter9.39e-021.00e+001.202411811
GO:0016328lateral plasma membrane9.42e-021.00e+003.3421346
GO:0043525positive regulation of neuron apoptotic process9.42e-021.00e+003.3421246
GO:0045727positive regulation of translation9.42e-021.00e+003.3421146
GO:0001047core promoter binding9.42e-021.00e+003.3421146
GO:0001947heart looping1.00e-011.00e+003.2501149
GO:0003743translation initiation factor activity1.00e-011.00e+003.2501549
GO:0048471perinuclear region of cytoplasm1.01e-011.00e+001.41939523
GO:0034097response to cytokine1.02e-011.00e+003.2211150
GO:0001948glycoprotein binding1.02e-011.00e+003.2211250
GO:0007254JNK cascade1.04e-011.00e+003.1931351
GO:0003684damaged DNA binding1.04e-011.00e+003.1931251
GO:0045732positive regulation of protein catabolic process1.04e-011.00e+003.1931151
GO:0045454cell redox homeostasis1.06e-011.00e+003.1651152
GO:0034976response to endoplasmic reticulum stress1.06e-011.00e+003.1651152
GO:0016042lipid catabolic process1.06e-011.00e+003.1651252
GO:0006952defense response1.08e-011.00e+003.1371153
GO:0030666endocytic vesicle membrane1.10e-011.00e+003.1101254
GO:0051403stress-activated MAPK cascade1.10e-011.00e+003.1101454
GO:0019900kinase binding1.10e-011.00e+003.1101354
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding1.10e-011.00e+003.1101154
GO:0050680negative regulation of epithelial cell proliferation1.10e-011.00e+003.1101154
GO:0000226microtubule cytoskeleton organization1.12e-011.00e+003.0841155
GO:0046330positive regulation of JNK cascade1.12e-011.00e+003.0841155
GO:0006888ER to Golgi vesicle-mediated transport1.12e-011.00e+003.0841155
GO:0000932cytoplasmic mRNA processing body1.13e-011.00e+003.0581156
GO:0043065positive regulation of apoptotic process1.17e-011.00e+001.76726274
GO:0051087chaperone binding1.19e-011.00e+002.9831159
GO:0045216cell-cell junction organization1.19e-011.00e+002.9831259
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.19e-011.00e+002.9831159
GO:0010976positive regulation of neuron projection development1.21e-011.00e+002.9581260
GO:0032481positive regulation of type I interferon production1.23e-011.00e+002.9341361
GO:0005634nucleus1.23e-011.00e+000.43514664828
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity1.23e-011.00e+002.9341161
GO:0033138positive regulation of peptidyl-serine phosphorylation1.23e-011.00e+002.9341161
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.25e-011.00e+002.9111162
GO:0000776kinetochore1.27e-011.00e+002.8881363
GO:0006417regulation of translation1.27e-011.00e+002.8881463
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.29e-011.00e+002.8651264
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.30e-011.00e+002.8431665
GO:0034146toll-like receptor 5 signaling pathway1.30e-011.00e+002.8431565
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.30e-011.00e+002.8431665
GO:0034166toll-like receptor 10 signaling pathway1.30e-011.00e+002.8431565
GO:0006469negative regulation of protein kinase activity1.30e-011.00e+002.8431165
GO:0071260cellular response to mechanical stimulus1.32e-011.00e+002.8211366
GO:0009636response to toxic substance1.32e-011.00e+002.8211166
GO:0031295T cell costimulation1.34e-011.00e+002.7991367
GO:0030141secretory granule1.34e-011.00e+002.7991267
GO:0006338chromatin remodeling1.36e-011.00e+002.7781268
GO:0045666positive regulation of neuron differentiation1.36e-011.00e+002.7781168
GO:0050790regulation of catalytic activity1.38e-011.00e+002.7571169
GO:0006887exocytosis1.38e-011.00e+002.7571169
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.40e-011.00e+002.7361870
GO:0035264multicellular organism growth1.40e-011.00e+002.7361170
GO:0005783endoplasmic reticulum1.41e-011.00e+001.19736610
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway1.42e-011.00e+002.7151571
GO:0034329cell junction assembly1.42e-011.00e+002.7151271
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway1.42e-011.00e+002.7151571
GO:0042383sarcolemma1.42e-011.00e+002.7151271
GO:0005856cytoskeleton1.43e-011.00e+001.58426311
GO:0034162toll-like receptor 9 signaling pathway1.44e-011.00e+002.6951572
GO:0045087innate immune response1.44e-011.00e+001.183311616
GO:0034134toll-like receptor 2 signaling pathway1.45e-011.00e+002.6751573
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.45e-011.00e+002.6751673
GO:0003729mRNA binding1.45e-011.00e+002.6751373
GO:0000785chromatin1.45e-011.00e+002.6751273
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.47e-011.00e+002.6561874
GO:0005085guanyl-nucleotide exchange factor activity1.47e-011.00e+002.6561174
GO:0007265Ras protein signal transduction1.49e-011.00e+002.6361375
GO:0060070canonical Wnt signaling pathway1.49e-011.00e+002.6361275
GO:0019901protein kinase binding1.50e-011.00e+001.54329320
GO:0035666TRIF-dependent toll-like receptor signaling pathway1.51e-011.00e+002.6171576
GO:0044325ion channel binding1.53e-011.00e+002.5981377
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.53e-011.00e+002.5981677
GO:0008584male gonad development1.53e-011.00e+002.5981177
GO:0002756MyD88-independent toll-like receptor signaling pathway1.55e-011.00e+002.5801578
GO:0007411axon guidance1.55e-011.00e+001.51223327
GO:0017137Rab GTPase binding1.55e-011.00e+002.5801178
GO:0071013catalytic step 2 spliceosome1.56e-011.00e+002.5611179
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.56e-011.00e+002.5611879
GO:0010629negative regulation of gene expression1.58e-011.00e+002.5431280
GO:0031902late endosome membrane1.58e-011.00e+002.5431180
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.58e-011.00e+002.5431580
GO:0034138toll-like receptor 3 signaling pathway1.58e-011.00e+002.5431580
GO:0003682chromatin binding1.60e-011.00e+001.48124334
GO:0045177apical part of cell1.62e-011.00e+002.5081182
GO:0005794Golgi apparatus1.62e-011.00e+001.10638650
GO:0030336negative regulation of cell migration1.64e-011.00e+002.4901283
GO:0007517muscle organ development1.64e-011.00e+002.4901183
GO:0043197dendritic spine1.64e-011.00e+002.4901283
GO:0005179hormone activity1.65e-011.00e+002.4731184
GO:0047485protein N-terminus binding1.69e-011.00e+002.4391186
GO:0007160cell-matrix adhesion1.73e-011.00e+002.4061188
GO:0050852T cell receptor signaling pathway1.73e-011.00e+002.4061288
GO:0000187activation of MAPK activity1.76e-011.00e+002.3731390
GO:0030054cell junction1.77e-011.00e+001.38924356
GO:0000922spindle pole1.78e-011.00e+002.3571591
GO:0018279protein N-linked glycosylation via asparagine1.78e-011.00e+002.3571191
GO:0006928cellular component movement1.80e-011.00e+002.3421492
GO:0016363nuclear matrix1.80e-011.00e+002.3421492
GO:0016605PML body1.80e-011.00e+002.3421292
GO:0042470melanosome1.80e-011.00e+002.3421292
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity1.81e-011.00e+002.3261193
GO:0001649osteoblast differentiation1.85e-011.00e+002.2951395
GO:0051082unfolded protein binding1.85e-011.00e+002.2951195
GO:0034142toll-like receptor 4 signaling pathway1.87e-011.00e+002.2801596
GO:0006364rRNA processing1.87e-011.00e+002.2801896
GO:0030426growth cone1.88e-011.00e+002.2651397
GO:0071456cellular response to hypoxia1.90e-011.00e+002.2501398
GO:0004888transmembrane signaling receptor activity1.99e-011.00e+002.17911103
GO:0005096GTPase activator activity2.08e-011.00e+002.11013108
GO:0002224toll-like receptor signaling pathway2.09e-011.00e+002.09715109
GO:0030496midbody2.09e-011.00e+002.09714109
GO:0005938cell cortex2.09e-011.00e+002.09711109
GO:0005815microtubule organizing center2.11e-011.00e+002.08414110
GO:0015630microtubule cytoskeleton2.14e-011.00e+002.05814112
GO:0003700sequence-specific DNA binding transcription factor activity2.15e-011.00e+000.90339748
GO:0005819spindle2.18e-011.00e+002.03214114
GO:0072562blood microparticle2.21e-011.00e+002.00711116
GO:0097190apoptotic signaling pathway2.21e-011.00e+002.00713116
GO:0000209protein polyubiquitination2.21e-011.00e+002.00717116
GO:0005802trans-Golgi network2.21e-011.00e+002.00712116
GO:0005635nuclear envelope2.21e-011.00e+002.00712116
GO:0006006glucose metabolic process2.26e-011.00e+001.97014119
GO:0032496response to lipopolysaccharide2.31e-011.00e+001.93411122
GO:0016192vesicle-mediated transport2.31e-011.00e+001.93411122
GO:0006325chromatin organization2.33e-011.00e+001.92312123
GO:0051056regulation of small GTPase mediated signal transduction2.33e-011.00e+001.92313123
GO:0007568aging2.33e-011.00e+001.92312123
GO:0051092positive regulation of NF-kappaB transcription factor activity2.36e-011.00e+001.89913125
GO:0007219Notch signaling pathway2.36e-011.00e+001.89914125
GO:0007050cell cycle arrest2.38e-011.00e+001.88812126
GO:0006511ubiquitin-dependent protein catabolic process2.39e-011.00e+001.87613127
GO:0008201heparin binding2.39e-011.00e+001.87611127
GO:0007179transforming growth factor beta receptor signaling pathway2.44e-011.00e+001.84314130
GO:0046983protein dimerization activity2.46e-011.00e+001.83213131
GO:0009615response to virus2.48e-011.00e+001.82114132
GO:0006351transcription, DNA-templated2.49e-011.00e+000.5575171585
GO:0007596blood coagulation2.62e-011.00e+001.00725464
GO:0007507heart development2.62e-011.00e+001.72611141
GO:0005911cell-cell junction2.64e-011.00e+001.71512142
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling2.73e-011.00e+001.65613148
GO:0010628positive regulation of gene expression2.75e-011.00e+001.64614149
GO:0008017microtubule binding2.76e-011.00e+001.63612150
GO:0001666response to hypoxia2.76e-011.00e+001.63611150
GO:0051260protein homooligomerization2.76e-011.00e+001.63612150
GO:0030246carbohydrate binding2.78e-011.00e+001.62711151
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription2.78e-011.00e+001.62712151
GO:0042802identical protein binding2.84e-011.00e+000.92624491
GO:0010008endosome membrane2.87e-011.00e+001.57112157
GO:0008543fibroblast growth factor receptor signaling pathway2.90e-011.00e+001.55213159
GO:0043005neuron projection2.93e-011.00e+001.53416161
GO:0045121membrane raft2.93e-011.00e+001.53413161
GO:0000398mRNA splicing, via spliceosome3.00e-011.00e+001.49912165
GO:0034220ion transmembrane transport3.03e-011.00e+001.48112167
GO:0007601visual perception3.04e-011.00e+001.47311168
GO:0038095Fc-epsilon receptor signaling pathway3.09e-011.00e+001.44713171
GO:0016607nuclear speck3.15e-011.00e+001.41412175
GO:0031965nuclear membrane3.16e-011.00e+001.40612176
GO:0007049cell cycle3.18e-011.00e+001.39814177
GO:0019904protein domain specific binding3.23e-011.00e+001.36513181
GO:0043687post-translational protein modification3.23e-011.00e+001.36511181
GO:0015629actin cytoskeleton3.26e-011.00e+001.34913183
GO:0006367transcription initiation from RNA polymerase II promoter3.28e-011.00e+001.34215184
GO:0003924GTPase activity3.55e-011.00e+001.20016203
GO:0030168platelet activation3.58e-011.00e+001.18614205
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.62e-011.00e+000.66329589
GO:0005509calcium ion binding3.62e-011.00e+000.66324589
GO:0001701in utero embryonic development3.65e-011.00e+001.15112210
GO:0006184GTP catabolic process3.78e-011.00e+001.08416220
GO:0042803protein homodimerization activity3.84e-011.00e+000.59624617
GO:0019221cytokine-mediated signaling pathway3.92e-011.00e+001.02015230
GO:0003713transcription coactivator activity4.04e-011.00e+000.96416239
GO:0005886plasma membrane4.07e-011.00e+000.2047242834
GO:0007399nervous system development4.11e-011.00e+000.92911245
GO:0005654nucleoplasm4.20e-011.00e+000.3533261095
GO:0006281DNA repair4.35e-011.00e+000.82115264
GO:0000166nucleotide binding4.45e-011.00e+000.77812272
GO:0048011neurotrophin TRK receptor signaling pathway4.46e-011.00e+000.77215273
GO:0005975carbohydrate metabolic process4.47e-011.00e+000.76713274
GO:0003779actin binding4.49e-011.00e+000.76213275
GO:0007283spermatogenesis4.50e-011.00e+000.75712276
GO:0007264small GTPase mediated signal transduction4.66e-011.00e+000.68517290
GO:0030198extracellular matrix organization4.72e-011.00e+000.66111295
GO:0030154cell differentiation5.06e-011.00e+000.52113325
GO:0005525GTP binding5.09e-011.00e+000.50816328
GO:0043231intracellular membrane-bounded organelle5.13e-011.00e+000.49013332
GO:0007275multicellular organismal development5.26e-011.00e+000.43912344
GO:0007268synaptic transmission5.35e-011.00e+000.40211353
GO:0003677DNA binding5.63e-011.00e+000.0503141351
GO:0009986cell surface6.01e-011.00e+000.14411422
GO:0045892negative regulation of transcription, DNA-templated6.02e-011.00e+000.13712424
GO:0006366transcription from RNA polymerase II promoter6.03e-011.00e+000.13413425
GO:0043066negative regulation of apoptotic process6.10e-011.00e+000.107114433
GO:0006468protein phosphorylation6.38e-011.00e+00-0.00216467
GO:0005615extracellular space6.47e-011.00e+00-0.115231010
GO:0055114oxidation-reduction process6.49e-011.00e+00-0.04512481
GO:0045893positive regulation of transcription, DNA-templated6.54e-011.00e+00-0.06318487
GO:0055085transmembrane transport6.74e-011.00e+00-0.14013514
GO:0006355regulation of transcription, DNA-templated6.95e-011.00e+00-0.2432101104
GO:0006915apoptotic process7.13e-011.00e+00-0.29219571
GO:0005789endoplasmic reticulum membrane7.52e-011.00e+00-0.44813636
GO:0046872metal ion binding8.35e-011.00e+00-0.6522141465
GO:0007165signal transduction8.78e-011.00e+00-1.02717950
GO:0005887integral component of plasma membrane8.81e-011.00e+00-1.04312961
GO:0008270zinc ion binding9.06e-011.00e+00-1.194171067
GO:0044281small molecule metabolic process9.45e-011.00e+00-1.4741161295
GO:0005524ATP binding9.52e-011.00e+00-1.5381191354
GO:0016021integral component of membrane9.97e-011.00e+00-2.413142483