int-snw-6210

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
tai-screen-luciferase 7.555 1.96e-202 4.38e-11 4.46e-05
tai-screen-luciferase-int-snw-6210 subnetwork

Genes (14)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS8 6202 10-5.5457.555234--
RPS4X 6191 18-6.7477.555263Yes-
CHMP2A 27243 10-9.0377.55541YesYes
COPZ1 22818 32-8.3019.06313YesYes
COPA 1314 32-9.3959.063170YesYes
[ RPS15A ] 6210 8-5.4137.555177Yes-
CDC42 998 11-6.9608.389265YesYes
RPS27A 6233 15-5.6318.389342Yes-
RPS11 6205 17-6.5887.555175Yes-
RPS24 6229 21-7.0348.389217Yes-
ARCN1 372 32-8.2329.063118YesYes
RPS9 6203 18-7.1277.555140Yes-
COPB2 9276 32-13.1689.06341YesYes
RPS13 6207 17-6.5897.555174Yes-

Interactions (31)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS27A 6233 pp -- int.I2D: YeastLow
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
RPS13 6207 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium

Related GO terms (225)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit3.94e-185.68e-147.72382039
GO:0019058viral life cycle1.83e-162.65e-126.333923115
GO:0019083viral transcription2.03e-152.93e-116.66982081
GO:0006415translational termination3.68e-155.30e-116.56682087
GO:0006414translational elongation6.39e-159.22e-116.47082093
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.61e-142.32e-106.308820104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3.43e-144.94e-106.176820114
GO:0006413translational initiation1.07e-131.54e-095.975821131
GO:0003735structural constituent of ribosome1.54e-132.23e-095.911822137
GO:0016071mRNA metabolic process7.99e-121.15e-075.208825223
GO:0006412translation1.02e-111.48e-075.163823230
GO:0016070RNA metabolic process1.82e-112.62e-075.060825247
GO:0005829cytosol2.10e-113.02e-072.53114612496
GO:0016032viral process2.08e-102.99e-064.118933534
GO:0030126COPI vesicle coat2.74e-103.95e-068.4244712
GO:0048205COPI coating of Golgi vesicle3.95e-105.70e-068.3084813
GO:0016020membrane4.40e-106.35e-062.87912411681
GO:0061024membrane organization2.62e-093.77e-055.414612145
GO:0044267cellular protein metabolic process3.24e-094.67e-054.120823474
GO:0006890retrograde vesicle-mediated transport, Golgi to ER6.94e-091.00e-047.3654825
GO:0010467gene expression4.82e-086.95e-043.623829669
GO:0044822poly(A) RNA binding8.37e-081.21e-033.1349321056
GO:0005840ribosome2.29e-073.30e-036.1514858
GO:0015935small ribosomal subunit4.91e-077.08e-037.5063917
GO:0005925focal adhesion6.48e-079.35e-034.078619366
GO:0019843rRNA binding2.10e-063.03e-026.8393427
GO:0070062extracellular vesicular exosome8.36e-061.21e-012.10210402400
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)8.74e-061.26e-018.687235
GO:0006886intracellular protein transport1.74e-052.51e-014.59147171
GO:0006891intra-Golgi vesicle-mediated transport1.18e-041.00e+006.9212417
GO:0030529ribonucleoprotein complex1.56e-041.00e+004.78637112
GO:0036464cytoplasmic ribonucleoprotein granule2.00e-041.00e+006.5492322
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway5.41e-041.00e+005.8392336
GO:0021691cerebellar Purkinje cell layer maturation9.71e-041.00e+0010.009111
GO:0016197endosomal transport1.35e-031.00e+005.1762357
GO:0071338positive regulation of hair follicle cell proliferation1.94e-031.00e+009.009112
GO:0090135actin filament branching1.94e-031.00e+009.009112
GO:0060661submandibular salivary gland formation1.94e-031.00e+009.009112
GO:0051683establishment of Golgi localization2.91e-031.00e+008.424123
GO:0034191apolipoprotein A-I receptor binding2.91e-031.00e+008.424113
GO:0003161cardiac conduction system development2.91e-031.00e+008.424113
GO:0060684epithelial-mesenchymal cell signaling3.88e-031.00e+008.009114
GO:0051835positive regulation of synapse structural plasticity3.88e-031.00e+008.009114
GO:0048664neuron fate determination3.88e-031.00e+008.009114
GO:0072384organelle transport along microtubule3.88e-031.00e+008.009124
GO:0035088establishment or maintenance of apical/basal cell polarity4.84e-031.00e+007.687115
GO:0033119negative regulation of RNA splicing4.84e-031.00e+007.687125
GO:0036336dendritic cell migration4.84e-031.00e+007.687115
GO:1902188positive regulation of viral release from host cell4.84e-031.00e+007.687115
GO:0031256leading edge membrane4.84e-031.00e+007.687115
GO:0008284positive regulation of cell proliferation5.40e-031.00e+003.01637382
GO:0060789hair follicle placode formation5.81e-031.00e+007.424116
GO:0007097nuclear migration5.81e-031.00e+007.424116
GO:0003334keratinocyte development5.81e-031.00e+007.424116
GO:0045182translation regulator activity5.81e-031.00e+007.424126
GO:0048554positive regulation of metalloenzyme activity5.81e-031.00e+007.424116
GO:0043497regulation of protein heterodimerization activity5.81e-031.00e+007.424116
GO:0050792regulation of viral process5.81e-031.00e+007.424116
GO:0030157pancreatic juice secretion6.78e-031.00e+007.201117
GO:0051988regulation of attachment of spindle microtubules to kinetochore6.78e-031.00e+007.201117
GO:0034101erythrocyte homeostasis6.78e-031.00e+007.201117
GO:0051489regulation of filopodium assembly6.78e-031.00e+007.201117
GO:0039702viral budding via host ESCRT complex7.74e-031.00e+007.009118
GO:0090136epithelial cell-cell adhesion8.70e-031.00e+006.839119
GO:0005198structural molecule activity9.01e-031.00e+003.78026150
GO:0031274positive regulation of pseudopodium assembly9.67e-031.00e+006.6871210
GO:0060047heart contraction9.67e-031.00e+006.6871110
GO:1903543positive regulation of exosomal secretion1.16e-021.00e+006.4241112
GO:0019082viral protein processing1.16e-021.00e+006.4241212
GO:0042274ribosomal small subunit biogenesis1.16e-021.00e+006.4241612
GO:0032479regulation of type I interferon production1.26e-021.00e+006.3081213
GO:0031333negative regulation of protein complex assembly1.35e-021.00e+006.2011114
GO:0031996thioesterase binding1.35e-021.00e+006.2011114
GO:0030131clathrin adaptor complex1.35e-021.00e+006.2011214
GO:0007173epidermal growth factor receptor signaling pathway1.40e-021.00e+003.44624189
GO:0031369translation initiation factor binding1.45e-021.00e+006.1021115
GO:0051233spindle midzone1.45e-021.00e+006.1021215
GO:0030225macrophage differentiation1.45e-021.00e+006.1021115
GO:0042176regulation of protein catabolic process1.54e-021.00e+006.0091316
GO:0075733intracellular transport of virus1.64e-021.00e+005.9211317
GO:0030742GTP-dependent protein binding1.64e-021.00e+005.9211117
GO:0019068virion assembly1.64e-021.00e+005.9211217
GO:0090316positive regulation of intracellular protein transport1.64e-021.00e+005.9211117
GO:0007088regulation of mitosis1.73e-021.00e+005.8391118
GO:0046847filopodium assembly1.83e-021.00e+005.7611119
GO:0043473pigmentation1.92e-021.00e+005.6871120
GO:0031435mitogen-activated protein kinase kinase kinase binding2.02e-021.00e+005.6161121
GO:0031424keratinization2.12e-021.00e+005.5491122
GO:0007220Notch receptor processing2.12e-021.00e+005.5491222
GO:0045787positive regulation of cell cycle2.12e-021.00e+005.5491222
GO:1900026positive regulation of substrate adhesion-dependent cell spreading2.21e-021.00e+005.4851123
GO:0005844polysome2.21e-021.00e+005.4851223
GO:0002040sprouting angiogenesis2.21e-021.00e+005.4851123
GO:0051017actin filament bundle assembly2.21e-021.00e+005.4851123
GO:0007163establishment or maintenance of cell polarity2.31e-021.00e+005.4241124
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway2.40e-021.00e+005.3651225
GO:0005978glycogen biosynthetic process2.50e-021.00e+005.3081226
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity2.50e-021.00e+005.3081226
GO:0045859regulation of protein kinase activity2.50e-021.00e+005.3081126
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.50e-021.00e+005.3081226
GO:0051149positive regulation of muscle cell differentiation2.59e-021.00e+005.2541127
GO:0032467positive regulation of cytokinesis2.59e-021.00e+005.2541127
GO:0045184establishment of protein localization2.59e-021.00e+005.2541227
GO:0031069hair follicle morphogenesis2.59e-021.00e+005.2541127
GO:0072686mitotic spindle2.78e-021.00e+005.1511129
GO:0031647regulation of protein stability2.87e-021.00e+005.1021130
GO:0032480negative regulation of type I interferon production3.06e-021.00e+005.0091232
GO:0042692muscle cell differentiation3.25e-021.00e+004.9211134
GO:0034332adherens junction organization3.44e-021.00e+004.8391236
GO:0045740positive regulation of DNA replication3.44e-021.00e+004.8391136
GO:0007249I-kappaB kinase/NF-kappaB signaling3.91e-021.00e+004.6511341
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway4.10e-021.00e+004.5821243
GO:0021762substantia nigra development4.19e-021.00e+004.5491144
GO:0034613cellular protein localization4.19e-021.00e+004.5491244
GO:0045727positive regulation of translation4.19e-021.00e+004.5491144
GO:0008344adult locomotory behavior4.19e-021.00e+004.5491144
GO:0043525positive regulation of neuron apoptotic process4.38e-021.00e+004.4851246
GO:0007030Golgi organization4.65e-021.00e+004.3941249
GO:0007254JNK cascade4.65e-021.00e+004.3941349
GO:0030175filopodium4.75e-021.00e+004.3651250
GO:0005737cytoplasm4.77e-021.00e+000.9377433767
GO:0030666endocytic vesicle membrane5.03e-021.00e+004.2811253
GO:0051403stress-activated MAPK cascade5.12e-021.00e+004.2541354
GO:0046330positive regulation of JNK cascade5.21e-021.00e+004.2271155
GO:0033138positive regulation of peptidyl-serine phosphorylation5.58e-021.00e+004.1261159
GO:0032481positive regulation of type I interferon production5.76e-021.00e+004.0781361
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway5.76e-021.00e+004.0781261
GO:0030141secretory granule5.86e-021.00e+004.0551162
GO:0006417regulation of translation5.86e-021.00e+004.0551262
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest6.04e-021.00e+004.0091664
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.13e-021.00e+003.9861665
GO:0034146toll-like receptor 5 signaling pathway6.13e-021.00e+003.9861465
GO:0031295T cell costimulation6.13e-021.00e+003.9861365
GO:0034166toll-like receptor 10 signaling pathway6.13e-021.00e+003.9861465
GO:0035264multicellular organism growth6.31e-021.00e+003.9431167
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.59e-021.00e+003.8791870
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway6.68e-021.00e+003.8591471
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway6.68e-021.00e+003.8591471
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent6.77e-021.00e+003.8391672
GO:0003729mRNA binding6.77e-021.00e+003.8391272
GO:0034162toll-like receptor 9 signaling pathway6.77e-021.00e+003.8391472
GO:0034134toll-like receptor 2 signaling pathway6.86e-021.00e+003.8191473
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis6.95e-021.00e+003.7991274
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle6.95e-021.00e+003.7991874
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I7.04e-021.00e+003.7801675
GO:0060070canonical Wnt signaling pathway7.04e-021.00e+003.7801175
GO:0035666TRIF-dependent toll-like receptor signaling pathway7.13e-021.00e+003.7611476
GO:0031902late endosome membrane7.22e-021.00e+003.7421277
GO:0010629negative regulation of gene expression7.22e-021.00e+003.7421277
GO:0002756MyD88-independent toll-like receptor signaling pathway7.31e-021.00e+003.7231478
GO:0005179hormone activity7.40e-021.00e+003.7051179
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process7.40e-021.00e+003.7051879
GO:0034138toll-like receptor 3 signaling pathway7.40e-021.00e+003.7051479
GO:0002755MyD88-dependent toll-like receptor signaling pathway7.49e-021.00e+003.6871480
GO:0045177apical part of cell7.59e-021.00e+003.6691181
GO:0050852T cell receptor signaling pathway7.95e-021.00e+003.5991285
GO:0000187activation of MAPK activity8.39e-021.00e+003.5171290
GO:0001649osteoblast differentiation8.57e-021.00e+003.4851392
GO:0071456cellular response to hypoxia8.57e-021.00e+003.4851392
GO:0002474antigen processing and presentation of peptide antigen via MHC class I8.57e-021.00e+003.4851692
GO:0006364rRNA processing8.75e-021.00e+003.4541794
GO:0034142toll-like receptor 4 signaling pathway8.93e-021.00e+003.4241496
GO:0030496midbody9.99e-021.00e+003.25412108
GO:0002224toll-like receptor signaling pathway1.01e-011.00e+003.24114109
GO:0005815microtubule organizing center1.01e-011.00e+003.24113109
GO:0097190apoptotic signaling pathway1.04e-011.00e+003.18913113
GO:0051056regulation of small GTPase mediated signal transduction1.06e-011.00e+003.16314115
GO:0000209protein polyubiquitination1.07e-011.00e+003.15117116
GO:0006006glucose metabolic process1.09e-011.00e+003.12613118
GO:0007219Notch signaling pathway1.10e-011.00e+003.10213120
GO:0045087innate immune response1.12e-011.00e+001.79028596
GO:0030036actin cytoskeleton organization1.13e-011.00e+003.06612123
GO:0051092positive regulation of NF-kappaB transcription factor activity1.14e-011.00e+003.05513124
GO:0009615response to virus1.16e-011.00e+003.03112126
GO:0007179transforming growth factor beta receptor signaling pathway1.17e-011.00e+003.00913128
GO:0000086G2/M transition of mitotic cell cycle1.24e-011.00e+002.92115136
GO:0005911cell-cell junction1.24e-011.00e+002.92112136
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling1.32e-011.00e+002.82913145
GO:0010628positive regulation of gene expression1.33e-011.00e+002.81914146
GO:0034220ion transmembrane transport1.35e-011.00e+002.79012149
GO:0000082G1/S transition of mitotic cell cycle1.35e-011.00e+002.79019149
GO:0042981regulation of apoptotic process1.36e-011.00e+002.78017150
GO:0010008endosome membrane1.37e-011.00e+002.77015151
GO:0008543fibroblast growth factor receptor signaling pathway1.41e-011.00e+002.72313156
GO:0043005neuron projection1.42e-011.00e+002.71416157
GO:0038095Fc-epsilon receptor signaling pathway1.51e-011.00e+002.61613168
GO:0019904protein domain specific binding1.60e-011.00e+002.52513179
GO:0006367transcription initiation from RNA polymerase II promoter1.65e-011.00e+002.48513184
GO:0003924GTPase activity1.75e-011.00e+002.38717197
GO:0006184GTP catabolic process1.89e-011.00e+002.26717214
GO:0019221cytokine-mediated signaling pathway1.94e-011.00e+002.22112221
GO:0005730nucleolus2.08e-011.00e+000.9133241641
GO:0043025neuronal cell body2.13e-011.00e+002.07214245
GO:0005975carbohydrate metabolic process2.20e-011.00e+002.02613253
GO:0000166nucleotide binding2.24e-011.00e+001.99212259
GO:0006281DNA repair2.26e-011.00e+001.98114261
GO:0043065positive regulation of apoptotic process2.31e-011.00e+001.94316268
GO:0048011neurotrophin TRK receptor signaling pathway2.32e-011.00e+001.93714269
GO:0007264small GTPase mediated signal transduction2.39e-011.00e+001.88517279
GO:0005525GTP binding2.62e-011.00e+001.73317310
GO:0019901protein kinase binding2.67e-011.00e+001.70016317
GO:0007275multicellular organismal development2.67e-011.00e+001.70511316
GO:0043231intracellular membrane-bounded organelle2.68e-011.00e+001.69615318
GO:0007411axon guidance2.69e-011.00e+001.69113319
GO:0015031protein transport2.85e-011.00e+001.59518341
GO:0003723RNA binding2.85e-011.00e+001.59118342
GO:0000139Golgi membrane2.99e-011.00e+001.51316361
GO:0000278mitotic cell cycle3.20e-011.00e+001.398111391
GO:0043066negative regulation of apoptotic process3.42e-011.00e+001.281113424
GO:0055085transmembrane transport3.49e-011.00e+001.24413435
GO:0007596blood coagulation3.62e-011.00e+001.17913455
GO:0042802identical protein binding3.80e-011.00e+001.09013484
GO:0006915apoptotic process4.23e-011.00e+000.89219555
GO:0005783endoplasmic reticulum4.23e-011.00e+000.89013556
GO:0000122negative regulation of transcription from RNA polymerase II promoter4.32e-011.00e+000.85417570
GO:0005794Golgi apparatus4.54e-011.00e+000.75619610
GO:0045944positive regulation of transcription from RNA polymerase II promoter5.45e-011.00e+000.38516789
GO:0005615extracellular space6.18e-011.00e+000.10612957
GO:0005654nucleoplasm6.65e-011.00e+00-0.0711151082
GO:0005634nucleus6.92e-011.00e+00-0.1464434559
GO:0044281small molecule metabolic process7.07e-011.00e+00-0.2331151211
GO:0046872metal ion binding7.36e-011.00e+00-0.3431101307
GO:0005886plasma membrane7.44e-011.00e+00-0.3262202582
GO:0005515protein binding7.64e-011.00e+00-0.2265626024
GO:0006351transcription, DNA-templated7.72e-011.00e+00-0.489161446