meta-int-snw-23433

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
reg-snw-60	tai-screen-luciferase	4.243	1.88e-19	3.43e-03	4.71e-03	12	5
int-snw-23433	tai-screen-luciferase	6.337	2.49e-134	4.62e-07	2.89e-03	10	7
reg-snw-1121	tai-screen-luciferase	4.707	1.91e-24	5.19e-04	8.44e-04	5	3
reg-snw-821	tai-screen-luciferase	4.344	1.76e-20	2.34e-03	3.35e-03	11	4
reg-snw-51164	tai-screen-luciferase	4.586	4.41e-23	8.78e-04	1.37e-03	6	4
reg-snw-57120	tai-screen-luciferase	4.450	1.33e-21	1.54e-03	2.29e-03	12	6

tai-screen-luciferase-meta-int-snw-23433 subnetwork

Genes (30)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	List-Gonzales GI	Tai-Hits
HES4	57801	19	-4.153	4.450	10	-	-
RHOQ	23433	6	1.414	6.337	19	-	-
DMD	1756	15	-4.338	4.243	53	-	-
CDC42EP2	10435	6	-2.649	6.337	5	-	-
COPA	1314	48	-9.395	5.672	340	Yes	Yes
PAFAH1B1	5048	18	-2.583	4.586	55	Yes	-
GOPC	57120	19	1.749	4.450	68	-	-
CAPRIN1	4076	14	-2.226	4.688	42	-	-
TNFRSF8	943	19	-4.106	4.450	15	-	-
CUL4B	8450	21	-2.809	5.269	142	-	-
HSF1	3297	46	-4.179	5.027	209	-	Yes
ARFGEF1	10565	13	-2.722	4.344	15	-	-
CANX	821	17	-1.959	4.504	65	-	-
COPB2	9276	48	-13.168	9.063	41	Yes	Yes
CKAP5	9793	46	-7.214	5.672	130	Yes	Yes
DNAJC10	54431	13	-2.349	4.344	11	-	-
COPZ1	22818	48	-8.301	9.063	13	Yes	Yes
RB1	5925	21	-2.085	4.707	351	-	-
EIF2S2	8894	31	-4.320	5.672	103	Yes	-
CHM	1121	13	-0.483	4.707	2	-	-
CDC42	998	44	-6.960	4.707	276	Yes	Yes
DCTN4	51164	13	-1.882	4.586	19	-	-
MRPS12	6183	35	-5.421	5.516	341	Yes	-
SRF	6722	15	1.994	4.243	23	-	-
ACTB	60	15	-1.716	4.243	23	-	-
ARCN1	372	48	-8.232	9.063	118	Yes	Yes
COPG1	22820	12	-5.279	7.138	37	Yes	Yes
COPB1	1315	39	-6.221	9.063	118	Yes	Yes
SERBP1	26135	35	-4.612	5.516	106	-	Yes
CDC5L	988	34	-3.419	5.672	155	-	-

Interactions (64)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
TNFRSF8	943	RB1	5925	pd	<	reg.pazar.txt: no annot
ARCN1	372	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
PAFAH1B1	5048	ARFGEF1	10565	pd	>	reg.ITFP.txt: no annot
COPZ1	22818	COPG1	22820	pp	--	int.I2D: BioGrid, HPRD, BIND; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association)
ACTB	60	CANX	821	pd	<	reg.ITFP.txt: no annot
COPA	1314	RB1	5925	pd	<>	reg.ITFP.txt: no annot
HSF1	3297	SRF	6722	pd	<>	reg.ITFP.txt: no annot
HSF1	3297	SRF	6722	pp	--	int.Yu: muscle
COPA	1314	DCTN4	51164	pd	>	reg.ITFP.txt: no annot
CDC5L	988	CUL4B	8450	pd	<>	reg.ITFP.txt: no annot
COPB2	9276	COPG1	22820	pp	--	int.I2D: BioGrid
RB1	5925	GOPC	57120	pd	>	reg.ITFP.txt: no annot
CANX	821	ARFGEF1	10565	pd	>	reg.ITFP.txt: no annot
CANX	821	CAPRIN1	4076	pd	>	reg.ITFP.txt: no annot
COPB1	1315	RHOQ	23433	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
RB1	5925	HES4	57801	pd	>	reg.pazar.txt: no annot
CDC42EP2	10435	RHOQ	23433	pp	--	int.I2D: BioGrid, HPRD, BIND; int.HPRD: in vitro, yeast 2-hybrid
CHM	1121	COPA	1314	pd	<	reg.ITFP.txt: no annot
RB1	5925	SERBP1	26135	pd	>	reg.pazar.txt: no annot
ACTB	60	MRPS12	6183	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPG1	22820	pp	--	int.I2D: HPRD; int.HPRD: in vivo
COPG1	22820	RHOQ	23433	pp	--	int.I2D: HPRD; int.HPRD: in vivo
CUL4B	8450	GOPC	57120	pd	>	reg.ITFP.txt: no annot
PAFAH1B1	5048	GOPC	57120	pd	>	reg.ITFP.txt: no annot
CAPRIN1	4076	CKAP5	9793	pd	<	reg.ITFP.txt: no annot
COPB1	1315	COPG1	22820	pp	--	int.I2D: BioGrid, HPRD; int.HPRD: in vitro, in vivo, yeast 2-hybrid; int.DIP: MI:0915(physical association)
CDC42	998	ARFGEF1	10565	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
RHOQ	23433	GOPC	57120	pp	--	int.I2D: BioGrid, HPRD; int.HPRD: in vitro, in vivo, yeast 2-hybrid
ACTB	60	RB1	5925	pd	<	reg.ITFP.txt: no annot
ACTB	60	COPA	1314	pd	<	reg.ITFP.txt: no annot
ACTB	60	COPA	1314	pp	--	int.I2D: BioGrid_Yeast
CAPRIN1	4076	CUL4B	8450	pd	<	reg.ITFP.txt: no annot
COPA	1314	COPB1	1315	pp	--	int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
CDC42	998	CDC42EP2	10435	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, HPRD, BIND, IntAct, SOURAV_MAPK_HIGH; int.HPRD: in vitro, in vivo
PAFAH1B1	5048	DCTN4	51164	pd	>	reg.ITFP.txt: no annot
DMD	1756	SRF	6722	pd	<	reg.pazar.txt: no annot; reg.TRANSFAC.txt: no annot
CANX	821	RB1	5925	pd	<>	reg.ITFP.txt: no annot
ACTB	60	PAFAH1B1	5048	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
CANX	821	MRPS12	6183	pp	--	int.I2D: BioGrid_Yeast
CDC42	998	GOPC	57120	pp	--	int.I2D: BioGrid
COPA	1314	COPB2	9276	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
COPB1	1315	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association)
CANX	821	COPA	1314	pd	<>	reg.ITFP.txt: no annot
COPA	1314	CAPRIN1	4076	pd	>	reg.ITFP.txt: no annot
ACTB	60	ARCN1	372	pp	--	int.I2D: BioGrid_Yeast
CUL4B	8450	DNAJC10	54431	pd	>	reg.ITFP.txt: no annot
HSF1	3297	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
RB1	5925	DCTN4	51164	pd	>	reg.ITFP.txt: no annot
COPA	1314	GOPC	57120	pd	>	reg.ITFP.txt: no annot
CDC5L	988	GOPC	57120	pd	>	reg.ITFP.txt: no annot
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
COPA	1314	CUL4B	8450	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot
COPB1	1315	COPB2	9276	pp	--	int.I2D: BioGrid
CHM	1121	RB1	5925	pd	<	reg.ITFP.txt: no annot
ARCN1	372	COPB1	1315	pp	--	int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo
CANX	821	DCTN4	51164	pd	>	reg.ITFP.txt: no annot
ARCN1	372	COPA	1314	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo
CDC42	998	RB1	5925	pd	<	reg.pazar.txt: no annot
CANX	821	DNAJC10	54431	pd	>	reg.ITFP.txt: no annot
COPB1	1315	ARFGEF1	10565	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPB2	9276	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
ACTB	60	SRF	6722	pd	<	reg.pazar.txt: no annot; reg.oreganno.txt: no annot
COPA	1314	PAFAH1B1	5048	pd	<>	reg.ITFP.txt: no annot

Related GO terms (524)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0048205	COPI coating of Golgi vesicle	3.85e-14	6.28e-10	7.972	6	6	13
GO:0030126	COPI vesicle coat	3.85e-14	6.28e-10	7.972	6	6	13
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	3.91e-12	6.39e-08	7.029	6	6	25
GO:0061024	membrane organization	6.80e-09	1.11e-04	4.705	7	11	146
GO:0005829	cytosol	3.09e-07	5.05e-03	1.852	17	74	2562
GO:0006886	intracellular protein transport	6.25e-07	1.02e-02	4.238	6	6	173
GO:0006891	intra-Golgi vesicle-mediated transport	3.75e-06	6.11e-02	6.585	3	3	17
GO:0016020	membrane	4.77e-06	7.78e-02	2.018	13	48	1746
GO:0051683	establishment of Golgi localization	9.79e-06	1.60e-01	8.503	2	2	3
GO:0043234	protein complex	1.50e-05	2.45e-01	3.444	6	9	300
GO:0072384	organelle transport along microtubule	1.96e-05	3.19e-01	8.088	2	2	4
GO:0007097	nuclear migration	6.82e-05	1.00e+00	7.280	2	2	7
GO:0090136	epithelial cell-cell adhesion	1.17e-04	1.00e+00	6.918	2	2	9
GO:0031274	positive regulation of pseudopodium assembly	1.46e-04	1.00e+00	6.766	2	2	10
GO:0005198	structural molecule activity	1.95e-04	1.00e+00	3.775	4	5	159
GO:0050998	nitric-oxide synthase binding	3.86e-04	1.00e+00	6.088	2	3	16
GO:0017022	myosin binding	4.91e-04	1.00e+00	5.918	2	2	18
GO:0005737	cytoplasm	5.95e-04	1.00e+00	1.130	16	65	3976
GO:0009306	protein secretion	6.71e-04	1.00e+00	5.695	2	2	21
GO:0036464	cytoplasmic ribonucleoprotein granule	7.37e-04	1.00e+00	5.628	2	5	22
GO:0051491	positive regulation of filopodium assembly	8.07e-04	1.00e+00	5.564	2	2	23
GO:0000139	Golgi membrane	8.10e-04	1.00e+00	2.737	5	7	408
GO:0005515	protein binding	1.14e-03	1.00e+00	0.829	20	87	6127
GO:0051219	phosphoprotein binding	1.57e-03	1.00e+00	5.088	2	4	32
GO:0030036	actin cytoskeleton organization	1.68e-03	1.00e+00	3.661	3	3	129
GO:0030038	contractile actin filament bundle assembly	1.84e-03	1.00e+00	9.088	1	1	1
GO:0045556	positive regulation of TRAIL biosynthetic process	1.84e-03	1.00e+00	9.088	1	1	1
GO:0090287	regulation of cellular response to growth factor stimulus	1.84e-03	1.00e+00	9.088	1	1	1
GO:0000235	astral microtubule	1.84e-03	1.00e+00	9.088	1	1	1
GO:0090284	positive regulation of protein glycosylation in Golgi	1.84e-03	1.00e+00	9.088	1	1	1
GO:0090230	regulation of centromere complex assembly	1.84e-03	1.00e+00	9.088	1	1	1
GO:0032427	GBD domain binding	1.84e-03	1.00e+00	9.088	1	1	1
GO:0043004	cytoplasmic sequestering of CFTR protein	1.84e-03	1.00e+00	9.088	1	1	1
GO:0021691	cerebellar Purkinje cell layer maturation	1.84e-03	1.00e+00	9.088	1	1	1
GO:0051660	establishment of centrosome localization	1.84e-03	1.00e+00	9.088	1	1	1
GO:0034975	protein folding in endoplasmic reticulum	1.84e-03	1.00e+00	9.088	1	1	1
GO:0046016	positive regulation of transcription by glucose	1.84e-03	1.00e+00	9.088	1	1	1
GO:0046469	platelet activating factor metabolic process	1.84e-03	1.00e+00	9.088	1	1	1
GO:0034332	adherens junction organization	1.98e-03	1.00e+00	4.918	2	4	36
GO:0021766	hippocampus development	2.32e-03	1.00e+00	4.802	2	3	39
GO:0044822	poly(A) RNA binding	2.86e-03	1.00e+00	1.821	7	42	1078
GO:0034613	cellular protein localization	2.95e-03	1.00e+00	4.628	2	2	44
GO:0021762	substantia nigra development	3.21e-03	1.00e+00	4.564	2	2	46
GO:0008344	adult locomotory behavior	3.35e-03	1.00e+00	4.533	2	2	47
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	3.55e-03	1.00e+00	3.280	3	4	168
GO:0010256	endomembrane system organization	3.67e-03	1.00e+00	8.088	1	1	2
GO:0071987	WD40-repeat domain binding	3.67e-03	1.00e+00	8.088	1	1	2
GO:0060661	submandibular salivary gland formation	3.67e-03	1.00e+00	8.088	1	1	2
GO:0036035	osteoclast development	3.67e-03	1.00e+00	8.088	1	1	2
GO:0014819	regulation of skeletal muscle contraction	3.67e-03	1.00e+00	8.088	1	1	2
GO:0086001	cardiac muscle cell action potential	3.67e-03	1.00e+00	8.088	1	1	2
GO:0071338	positive regulation of hair follicle cell proliferation	3.67e-03	1.00e+00	8.088	1	1	2
GO:0051081	nuclear envelope disassembly	3.67e-03	1.00e+00	8.088	1	1	2
GO:0002176	male germ cell proliferation	3.67e-03	1.00e+00	8.088	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	3.67e-03	1.00e+00	8.088	1	1	2
GO:0090135	actin filament branching	3.67e-03	1.00e+00	8.088	1	1	2
GO:0031134	sister chromatid biorientation	3.67e-03	1.00e+00	8.088	1	1	2
GO:0010736	serum response element binding	3.67e-03	1.00e+00	8.088	1	1	2
GO:0007070	negative regulation of transcription from RNA polymerase II promoter during mitosis	3.67e-03	1.00e+00	8.088	1	1	2
GO:0007030	Golgi organization	3.79e-03	1.00e+00	4.444	2	3	50
GO:0030424	axon	3.79e-03	1.00e+00	3.246	3	4	172
GO:0030175	filopodium	4.25e-03	1.00e+00	4.360	2	2	53
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	5.50e-03	1.00e+00	7.503	1	1	3
GO:0014809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	5.50e-03	1.00e+00	7.503	1	1	3
GO:0060947	cardiac vascular smooth muscle cell differentiation	5.50e-03	1.00e+00	7.503	1	1	3
GO:0003161	cardiac conduction system development	5.50e-03	1.00e+00	7.503	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	5.50e-03	1.00e+00	7.503	1	1	3
GO:1900222	negative regulation of beta-amyloid clearance	5.50e-03	1.00e+00	7.503	1	1	3
GO:1901385	regulation of voltage-gated calcium channel activity	5.50e-03	1.00e+00	7.503	1	1	3
GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	5.50e-03	1.00e+00	7.503	1	1	3
GO:0045505	dynein intermediate chain binding	5.50e-03	1.00e+00	7.503	1	1	3
GO:0022028	tangential migration from the subventricular zone to the olfactory bulb	5.50e-03	1.00e+00	7.503	1	1	3
GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	5.50e-03	1.00e+00	7.503	1	1	3
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	5.50e-03	1.00e+00	7.503	1	1	3
GO:0033561	regulation of water loss via skin	5.50e-03	1.00e+00	7.503	1	1	3
GO:0005850	eukaryotic translation initiation factor 2 complex	5.50e-03	1.00e+00	7.503	1	1	3
GO:0034663	endoplasmic reticulum chaperone complex	5.50e-03	1.00e+00	7.503	1	1	3
GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation	5.50e-03	1.00e+00	7.503	1	2	3
GO:0021540	corpus callosum morphogenesis	5.50e-03	1.00e+00	7.503	1	1	3
GO:0071922	regulation of cohesin localization to chromatin	7.33e-03	1.00e+00	7.088	1	2	4
GO:0034191	apolipoprotein A-I receptor binding	7.33e-03	1.00e+00	7.088	1	1	4
GO:0010669	epithelial structure maintenance	7.33e-03	1.00e+00	7.088	1	1	4
GO:0060684	epithelial-mesenchymal cell signaling	7.33e-03	1.00e+00	7.088	1	1	4
GO:0051835	positive regulation of synapse structural plasticity	7.33e-03	1.00e+00	7.088	1	1	4
GO:0015036	disulfide oxidoreductase activity	7.33e-03	1.00e+00	7.088	1	1	4
GO:0043550	regulation of lipid kinase activity	7.33e-03	1.00e+00	7.088	1	1	4
GO:0016013	syntrophin complex	7.33e-03	1.00e+00	7.088	1	2	4
GO:0090231	regulation of spindle checkpoint	7.33e-03	1.00e+00	7.088	1	1	4
GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	7.33e-03	1.00e+00	7.088	1	1	4
GO:0048664	neuron fate determination	7.33e-03	1.00e+00	7.088	1	1	4
GO:0010735	positive regulation of transcription via serum response element binding	7.33e-03	1.00e+00	7.088	1	1	4
GO:0005968	Rab-protein geranylgeranyltransferase complex	7.33e-03	1.00e+00	7.088	1	1	4
GO:0035189	Rb-E2F complex	7.33e-03	1.00e+00	7.088	1	1	4
GO:0034349	glial cell apoptotic process	7.33e-03	1.00e+00	7.088	1	1	4
GO:0034088	maintenance of mitotic sister chromatid cohesion	7.33e-03	1.00e+00	7.088	1	1	4
GO:0031175	neuron projection development	8.34e-03	1.00e+00	3.859	2	2	75
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	8.77e-03	1.00e+00	3.821	2	4	77
GO:0036336	dendritic cell migration	9.16e-03	1.00e+00	6.766	1	1	5
GO:2000651	positive regulation of sodium ion transmembrane transporter activity	9.16e-03	1.00e+00	6.766	1	1	5
GO:0035088	establishment or maintenance of apical/basal cell polarity	9.16e-03	1.00e+00	6.766	1	1	5
GO:0048667	cell morphogenesis involved in neuron differentiation	9.16e-03	1.00e+00	6.766	1	1	5
GO:0031256	leading edge membrane	9.16e-03	1.00e+00	6.766	1	1	5
GO:0044233	ER-mitochondrion membrane contact site	9.16e-03	1.00e+00	6.766	1	1	5
GO:0035912	dorsal aorta morphogenesis	9.16e-03	1.00e+00	6.766	1	1	5
GO:0001515	opioid peptide activity	9.16e-03	1.00e+00	6.766	1	1	5
GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	9.16e-03	1.00e+00	6.766	1	1	5
GO:0043043	peptide biosynthetic process	9.16e-03	1.00e+00	6.766	1	1	5
GO:0031023	microtubule organizing center organization	9.16e-03	1.00e+00	6.766	1	1	5
GO:0004663	Rab geranylgeranyltransferase activity	9.16e-03	1.00e+00	6.766	1	1	5
GO:0008134	transcription factor binding	1.02e-02	1.00e+00	2.730	3	5	246
GO:0043353	enucleate erythrocyte differentiation	1.10e-02	1.00e+00	6.503	1	1	6
GO:0007143	female meiotic division	1.10e-02	1.00e+00	6.503	1	1	6
GO:0044458	motile cilium assembly	1.10e-02	1.00e+00	6.503	1	1	6
GO:0051150	regulation of smooth muscle cell differentiation	1.10e-02	1.00e+00	6.503	1	1	6
GO:0018344	protein geranylgeranylation	1.10e-02	1.00e+00	6.503	1	1	6
GO:0060789	hair follicle placode formation	1.10e-02	1.00e+00	6.503	1	1	6
GO:0008090	retrograde axon cargo transport	1.10e-02	1.00e+00	6.503	1	1	6
GO:0048554	positive regulation of metalloenzyme activity	1.10e-02	1.00e+00	6.503	1	1	6
GO:0045842	positive regulation of mitotic metaphase/anaphase transition	1.10e-02	1.00e+00	6.503	1	1	6
GO:0001667	ameboidal-type cell migration	1.10e-02	1.00e+00	6.503	1	1	6
GO:0000974	Prp19 complex	1.10e-02	1.00e+00	6.503	1	1	6
GO:0030957	Tat protein binding	1.10e-02	1.00e+00	6.503	1	1	6
GO:0034452	dynactin binding	1.10e-02	1.00e+00	6.503	1	1	6
GO:0043025	neuronal cell body	1.11e-02	1.00e+00	2.684	3	5	254
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	1.23e-02	1.00e+00	3.564	2	3	92
GO:0005200	structural constituent of cytoskeleton	1.26e-02	1.00e+00	3.548	2	6	93
GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter	1.28e-02	1.00e+00	6.280	1	1	7
GO:0006893	Golgi to plasma membrane transport	1.28e-02	1.00e+00	6.280	1	1	7
GO:0060055	angiogenesis involved in wound healing	1.28e-02	1.00e+00	6.280	1	1	7
GO:0060136	embryonic process involved in female pregnancy	1.28e-02	1.00e+00	6.280	1	1	7
GO:0043497	regulation of protein heterodimerization activity	1.28e-02	1.00e+00	6.280	1	1	7
GO:0050658	RNA transport	1.28e-02	1.00e+00	6.280	1	1	7
GO:0003334	keratinocyte development	1.28e-02	1.00e+00	6.280	1	1	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	1.28e-02	1.00e+00	6.280	1	1	7
GO:0070914	UV-damage excision repair	1.28e-02	1.00e+00	6.280	1	1	7
GO:0001961	positive regulation of cytokine-mediated signaling pathway	1.28e-02	1.00e+00	6.280	1	1	7
GO:0002162	dystroglycan binding	1.28e-02	1.00e+00	6.280	1	1	7
GO:0030157	pancreatic juice secretion	1.28e-02	1.00e+00	6.280	1	1	7
GO:0017145	stem cell division	1.28e-02	1.00e+00	6.280	1	1	7
GO:0000930	gamma-tubulin complex	1.28e-02	1.00e+00	6.280	1	1	7
GO:0034259	negative regulation of Rho GTPase activity	1.28e-02	1.00e+00	6.280	1	1	7
GO:0001764	neuron migration	1.34e-02	1.00e+00	3.503	2	2	96
GO:0090005	negative regulation of establishment of protein localization to plasma membrane	1.46e-02	1.00e+00	6.088	1	1	8
GO:0090009	primitive streak formation	1.46e-02	1.00e+00	6.088	1	1	8
GO:0031512	motile primary cilium	1.46e-02	1.00e+00	6.088	1	1	8
GO:0043589	skin morphogenesis	1.46e-02	1.00e+00	6.088	1	1	8
GO:0007289	spermatid nucleus differentiation	1.46e-02	1.00e+00	6.088	1	1	8
GO:0005522	profilin binding	1.46e-02	1.00e+00	6.088	1	1	8
GO:0070688	MLL5-L complex	1.46e-02	1.00e+00	6.088	1	1	8
GO:0005869	dynactin complex	1.46e-02	1.00e+00	6.088	1	1	8
GO:0051489	regulation of filopodium assembly	1.46e-02	1.00e+00	6.088	1	1	8
GO:0061003	positive regulation of dendritic spine morphogenesis	1.46e-02	1.00e+00	6.088	1	1	8
GO:0008360	regulation of cell shape	1.61e-02	1.00e+00	3.360	2	2	106
GO:0014069	postsynaptic density	1.61e-02	1.00e+00	3.360	2	3	106
GO:0097284	hepatocyte apoptotic process	1.64e-02	1.00e+00	5.918	1	1	9
GO:0000983	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity	1.64e-02	1.00e+00	5.918	1	1	9
GO:0000075	cell cycle checkpoint	1.64e-02	1.00e+00	5.918	1	1	9
GO:0021895	cerebral cortex neuron differentiation	1.64e-02	1.00e+00	5.918	1	1	9
GO:0030837	negative regulation of actin filament polymerization	1.64e-02	1.00e+00	5.918	1	1	9
GO:0032319	regulation of Rho GTPase activity	1.64e-02	1.00e+00	5.918	1	1	9
GO:0045059	positive thymic T cell selection	1.64e-02	1.00e+00	5.918	1	1	9
GO:0015630	microtubule cytoskeleton	1.79e-02	1.00e+00	3.280	2	4	112
GO:0034237	protein kinase A regulatory subunit binding	1.82e-02	1.00e+00	5.766	1	1	10
GO:0051787	misfolded protein binding	1.82e-02	1.00e+00	5.766	1	1	10
GO:0005798	Golgi-associated vesicle	1.82e-02	1.00e+00	5.766	1	1	10
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process	1.82e-02	1.00e+00	5.766	1	1	10
GO:0017049	GTP-Rho binding	1.82e-02	1.00e+00	5.766	1	1	10
GO:0001076	RNA polymerase II transcription factor binding transcription factor activity	1.82e-02	1.00e+00	5.766	1	1	10
GO:0090303	positive regulation of wound healing	1.82e-02	1.00e+00	5.766	1	1	10
GO:0061029	eyelid development in camera-type eye	1.82e-02	1.00e+00	5.766	1	1	10
GO:0001675	acrosome assembly	1.82e-02	1.00e+00	5.766	1	1	10
GO:0060218	hematopoietic stem cell differentiation	1.82e-02	1.00e+00	5.766	1	1	10
GO:0060047	heart contraction	1.82e-02	1.00e+00	5.766	1	1	10
GO:0045502	dynein binding	2.00e-02	1.00e+00	5.628	1	1	11
GO:0045176	apical protein localization	2.00e-02	1.00e+00	5.628	1	1	11
GO:0017166	vinculin binding	2.00e-02	1.00e+00	5.628	1	1	11
GO:0042551	neuron maturation	2.00e-02	1.00e+00	5.628	1	1	11
GO:0045651	positive regulation of macrophage differentiation	2.00e-02	1.00e+00	5.628	1	1	11
GO:0045120	pronucleus	2.00e-02	1.00e+00	5.628	1	1	11
GO:0035518	histone H2A monoubiquitination	2.00e-02	1.00e+00	5.628	1	2	11
GO:0002011	morphogenesis of an epithelial sheet	2.00e-02	1.00e+00	5.628	1	1	11
GO:0021819	layer formation in cerebral cortex	2.00e-02	1.00e+00	5.628	1	1	11
GO:0051056	regulation of small GTPase mediated signal transduction	2.14e-02	1.00e+00	3.145	2	3	123
GO:0007051	spindle organization	2.18e-02	1.00e+00	5.503	1	1	12
GO:0051146	striated muscle cell differentiation	2.18e-02	1.00e+00	5.503	1	2	12
GO:0043149	stress fiber assembly	2.18e-02	1.00e+00	5.503	1	2	12
GO:0030140	trans-Golgi network transport vesicle	2.18e-02	1.00e+00	5.503	1	1	12
GO:0072583	clathrin-mediated endocytosis	2.18e-02	1.00e+00	5.503	1	1	12
GO:0047496	vesicle transport along microtubule	2.18e-02	1.00e+00	5.503	1	1	12
GO:0055003	cardiac myofibril assembly	2.18e-02	1.00e+00	5.503	1	1	12
GO:0042789	mRNA transcription from RNA polymerase II promoter	2.36e-02	1.00e+00	5.387	1	1	13
GO:0001671	ATPase activator activity	2.36e-02	1.00e+00	5.387	1	1	13
GO:0043488	regulation of mRNA stability	2.36e-02	1.00e+00	5.387	1	1	13
GO:0005662	DNA replication factor A complex	2.36e-02	1.00e+00	5.387	1	1	13
GO:1900087	positive regulation of G1/S transition of mitotic cell cycle	2.36e-02	1.00e+00	5.387	1	1	13
GO:0060314	regulation of ryanodine-sensitive calcium-release channel activity	2.36e-02	1.00e+00	5.387	1	1	13
GO:0035855	megakaryocyte development	2.36e-02	1.00e+00	5.387	1	1	13
GO:0005813	centrosome	2.38e-02	1.00e+00	2.267	3	9	339
GO:0000790	nuclear chromatin	2.47e-02	1.00e+00	3.032	2	2	133
GO:0035371	microtubule plus-end	2.54e-02	1.00e+00	5.280	1	1	14
GO:0031333	negative regulation of protein complex assembly	2.54e-02	1.00e+00	5.280	1	1	14
GO:0060292	long term synaptic depression	2.54e-02	1.00e+00	5.280	1	1	14
GO:0048488	synaptic vesicle endocytosis	2.54e-02	1.00e+00	5.280	1	1	14
GO:0035267	NuA4 histone acetyltransferase complex	2.54e-02	1.00e+00	5.280	1	2	14
GO:0031996	thioesterase binding	2.54e-02	1.00e+00	5.280	1	1	14
GO:0034185	apolipoprotein binding	2.54e-02	1.00e+00	5.280	1	1	14
GO:0031334	positive regulation of protein complex assembly	2.54e-02	1.00e+00	5.280	1	1	14
GO:0000086	G2/M transition of mitotic cell cycle	2.61e-02	1.00e+00	2.990	2	6	137
GO:0030131	clathrin adaptor complex	2.72e-02	1.00e+00	5.181	1	1	15
GO:0002042	cell migration involved in sprouting angiogenesis	2.72e-02	1.00e+00	5.181	1	1	15
GO:0030225	macrophage differentiation	2.72e-02	1.00e+00	5.181	1	1	15
GO:0016514	SWI/SNF complex	2.72e-02	1.00e+00	5.181	1	1	15
GO:0045987	positive regulation of smooth muscle contraction	2.72e-02	1.00e+00	5.181	1	1	15
GO:0045445	myoblast differentiation	2.72e-02	1.00e+00	5.181	1	1	15
GO:0048821	erythrocyte development	2.72e-02	1.00e+00	5.181	1	2	15
GO:0016010	dystrophin-associated glycoprotein complex	2.72e-02	1.00e+00	5.181	1	1	15
GO:2000114	regulation of establishment of cell polarity	2.72e-02	1.00e+00	5.181	1	1	15
GO:0051233	spindle midzone	2.72e-02	1.00e+00	5.181	1	2	15
GO:0048854	brain morphogenesis	2.72e-02	1.00e+00	5.181	1	1	15
GO:0060347	heart trabecula formation	2.72e-02	1.00e+00	5.181	1	1	15
GO:0032839	dendrite cytoplasm	2.90e-02	1.00e+00	5.088	1	1	16
GO:0007405	neuroblast proliferation	2.90e-02	1.00e+00	5.088	1	1	16
GO:0032012	regulation of ARF protein signal transduction	2.90e-02	1.00e+00	5.088	1	1	16
GO:0019226	transmission of nerve impulse	2.90e-02	1.00e+00	5.088	1	1	16
GO:0000132	establishment of mitotic spindle orientation	2.90e-02	1.00e+00	5.088	1	2	16
GO:0042176	regulation of protein catabolic process	2.90e-02	1.00e+00	5.088	1	4	16
GO:0033137	negative regulation of peptidyl-serine phosphorylation	2.90e-02	1.00e+00	5.088	1	1	16
GO:0030220	platelet formation	2.90e-02	1.00e+00	5.088	1	1	16
GO:0043623	cellular protein complex assembly	2.90e-02	1.00e+00	5.088	1	1	16
GO:0046716	muscle cell cellular homeostasis	2.90e-02	1.00e+00	5.088	1	1	16
GO:0050775	positive regulation of dendrite morphogenesis	2.90e-02	1.00e+00	5.088	1	1	16
GO:0008285	negative regulation of cell proliferation	2.92e-02	1.00e+00	2.153	3	3	367
GO:0005794	Golgi apparatus	3.00e-02	1.00e+00	1.743	4	8	650
GO:0006457	protein folding	3.05e-02	1.00e+00	2.868	2	3	149
GO:0035255	ionotropic glutamate receptor binding	3.08e-02	1.00e+00	5.000	1	1	17
GO:0010880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	3.08e-02	1.00e+00	5.000	1	1	17
GO:0043274	phospholipase binding	3.08e-02	1.00e+00	5.000	1	1	17
GO:0008306	associative learning	3.08e-02	1.00e+00	5.000	1	1	17
GO:0031527	filopodium membrane	3.08e-02	1.00e+00	5.000	1	1	17
GO:0001829	trophectodermal cell differentiation	3.08e-02	1.00e+00	5.000	1	1	17
GO:0015935	small ribosomal subunit	3.08e-02	1.00e+00	5.000	1	9	17
GO:0030742	GTP-dependent protein binding	3.08e-02	1.00e+00	5.000	1	1	17
GO:0070062	extracellular vesicular exosome	3.24e-02	1.00e+00	0.961	9	51	2516
GO:0006612	protein targeting to membrane	3.26e-02	1.00e+00	4.918	1	2	18
GO:0045773	positive regulation of axon extension	3.26e-02	1.00e+00	4.918	1	1	18
GO:0005086	ARF guanyl-nucleotide exchange factor activity	3.26e-02	1.00e+00	4.918	1	1	18
GO:0090316	positive regulation of intracellular protein transport	3.26e-02	1.00e+00	4.918	1	1	18
GO:0030532	small nuclear ribonucleoprotein complex	3.26e-02	1.00e+00	4.918	1	1	18
GO:0005788	endoplasmic reticulum lumen	3.35e-02	1.00e+00	2.793	2	2	157
GO:0007088	regulation of mitosis	3.44e-02	1.00e+00	4.840	1	1	19
GO:0010881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	3.44e-02	1.00e+00	4.840	1	1	19
GO:0030866	cortical actin cytoskeleton organization	3.44e-02	1.00e+00	4.840	1	1	19
GO:0045121	membrane raft	3.51e-02	1.00e+00	2.757	2	3	161
GO:0000278	mitotic cell cycle	3.59e-02	1.00e+00	2.036	3	16	398
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	3.61e-02	1.00e+00	4.766	1	1	20
GO:0090398	cellular senescence	3.61e-02	1.00e+00	4.766	1	1	20
GO:0030544	Hsp70 protein binding	3.61e-02	1.00e+00	4.766	1	1	20
GO:0043473	pigmentation	3.61e-02	1.00e+00	4.766	1	2	20
GO:0015035	protein disulfide oxidoreductase activity	3.79e-02	1.00e+00	4.695	1	1	21
GO:0043034	costamere	3.79e-02	1.00e+00	4.695	1	1	21
GO:0046847	filopodium assembly	3.79e-02	1.00e+00	4.695	1	1	21
GO:0005790	smooth endoplasmic reticulum	3.97e-02	1.00e+00	4.628	1	1	22
GO:0031435	mitogen-activated protein kinase kinase kinase binding	3.97e-02	1.00e+00	4.628	1	1	22
GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle	3.97e-02	1.00e+00	4.628	1	1	22
GO:0030863	cortical cytoskeleton	3.97e-02	1.00e+00	4.628	1	1	22
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	4.15e-02	1.00e+00	4.564	1	1	23
GO:0002040	sprouting angiogenesis	4.15e-02	1.00e+00	4.564	1	1	23
GO:0045879	negative regulation of smoothened signaling pathway	4.15e-02	1.00e+00	4.564	1	1	23
GO:0051017	actin filament bundle assembly	4.15e-02	1.00e+00	4.564	1	1	23
GO:0008060	ARF GTPase activator activity	4.15e-02	1.00e+00	4.564	1	1	23
GO:0001892	embryonic placenta development	4.15e-02	1.00e+00	4.564	1	1	23
GO:0051297	centrosome organization	4.15e-02	1.00e+00	4.564	1	2	23
GO:0043044	ATP-dependent chromatin remodeling	4.15e-02	1.00e+00	4.564	1	1	23
GO:0045211	postsynaptic membrane	4.17e-02	1.00e+00	2.620	2	3	177
GO:0031625	ubiquitin protein ligase binding	4.30e-02	1.00e+00	2.596	2	4	180
GO:0008135	translation factor activity, nucleic acid binding	4.32e-02	1.00e+00	4.503	1	4	24
GO:0005761	mitochondrial ribosome	4.32e-02	1.00e+00	4.503	1	1	24
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	4.32e-02	1.00e+00	4.503	1	1	24
GO:0007163	establishment or maintenance of cell polarity	4.32e-02	1.00e+00	4.503	1	2	24
GO:0046329	negative regulation of JNK cascade	4.32e-02	1.00e+00	4.503	1	1	24
GO:0005100	Rho GTPase activator activity	4.32e-02	1.00e+00	4.503	1	1	24
GO:0032781	positive regulation of ATPase activity	4.50e-02	1.00e+00	4.444	1	1	25
GO:0046326	positive regulation of glucose import	4.50e-02	1.00e+00	4.444	1	1	25
GO:0045931	positive regulation of mitotic cell cycle	4.67e-02	1.00e+00	4.387	1	2	26
GO:0045214	sarcomere organization	4.67e-02	1.00e+00	4.387	1	1	26
GO:0045859	regulation of protein kinase activity	4.67e-02	1.00e+00	4.387	1	1	26
GO:0048589	developmental growth	4.67e-02	1.00e+00	4.387	1	1	26
GO:0001707	mesoderm formation	4.67e-02	1.00e+00	4.387	1	1	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	4.67e-02	1.00e+00	4.387	1	2	26
GO:0071556	integral component of lumenal side of endoplasmic reticulum membrane	4.67e-02	1.00e+00	4.387	1	1	26
GO:0043547	positive regulation of GTPase activity	4.74e-02	1.00e+00	2.518	2	4	190
GO:0051149	positive regulation of muscle cell differentiation	4.85e-02	1.00e+00	4.333	1	2	27
GO:0032720	negative regulation of tumor necrosis factor production	4.85e-02	1.00e+00	4.333	1	1	27
GO:0007616	long-term memory	4.85e-02	1.00e+00	4.333	1	1	27
GO:0005083	small GTPase regulator activity	4.85e-02	1.00e+00	4.333	1	1	27
GO:0031424	keratinization	4.85e-02	1.00e+00	4.333	1	1	27
GO:0048565	digestive tract development	4.85e-02	1.00e+00	4.333	1	1	27
GO:0031069	hair follicle morphogenesis	4.85e-02	1.00e+00	4.333	1	1	27
GO:0032467	positive regulation of cytokinesis	5.03e-02	1.00e+00	4.280	1	1	28
GO:0031492	nucleosomal DNA binding	5.03e-02	1.00e+00	4.280	1	1	28
GO:0019894	kinesin binding	5.03e-02	1.00e+00	4.280	1	1	28
GO:0005875	microtubule associated complex	5.03e-02	1.00e+00	4.280	1	1	28
GO:0045597	positive regulation of cell differentiation	5.03e-02	1.00e+00	4.280	1	1	28
GO:0007017	microtubule-based process	5.03e-02	1.00e+00	4.280	1	2	28
GO:0031252	cell leading edge	5.20e-02	1.00e+00	4.230	1	3	29
GO:0003730	mRNA 3'-UTR binding	5.20e-02	1.00e+00	4.230	1	1	29
GO:0034605	cellular response to heat	5.20e-02	1.00e+00	4.230	1	1	29
GO:0072686	mitotic spindle	5.20e-02	1.00e+00	4.230	1	1	29
GO:0003924	GTPase activity	5.33e-02	1.00e+00	2.422	2	6	203
GO:0010977	negative regulation of neuron projection development	5.37e-02	1.00e+00	4.181	1	2	30
GO:0007346	regulation of mitotic cell cycle	5.37e-02	1.00e+00	4.181	1	3	30
GO:0031647	regulation of protein stability	5.37e-02	1.00e+00	4.181	1	1	30
GO:0032956	regulation of actin cytoskeleton organization	5.37e-02	1.00e+00	4.181	1	1	30
GO:0002027	regulation of heart rate	5.37e-02	1.00e+00	4.181	1	2	30
GO:0040018	positive regulation of multicellular organism growth	5.37e-02	1.00e+00	4.181	1	1	30
GO:0010494	cytoplasmic stress granule	5.37e-02	1.00e+00	4.181	1	2	30
GO:0061077	chaperone-mediated protein folding	5.55e-02	1.00e+00	4.133	1	1	31
GO:0007093	mitotic cell cycle checkpoint	5.55e-02	1.00e+00	4.133	1	2	31
GO:0070830	tight junction assembly	5.90e-02	1.00e+00	4.043	1	1	33
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.95e-02	1.00e+00	1.424	4	11	811
GO:0001569	patterning of blood vessels	6.07e-02	1.00e+00	4.000	1	1	34
GO:0007611	learning or memory	6.07e-02	1.00e+00	4.000	1	2	34
GO:0042692	muscle cell differentiation	6.07e-02	1.00e+00	4.000	1	2	34
GO:0044267	cellular protein metabolic process	6.15e-02	1.00e+00	1.721	3	29	495
GO:0006184	GTP catabolic process	6.15e-02	1.00e+00	2.306	2	6	220
GO:0048666	neuron development	6.24e-02	1.00e+00	3.958	1	1	35
GO:0071333	cellular response to glucose stimulus	6.24e-02	1.00e+00	3.958	1	2	35
GO:0009725	response to hormone	6.24e-02	1.00e+00	3.958	1	1	35
GO:0005886	plasma membrane	6.30e-02	1.00e+00	0.789	9	24	2834
GO:0051402	neuron apoptotic process	6.42e-02	1.00e+00	3.918	1	1	36
GO:0030838	positive regulation of actin filament polymerization	6.42e-02	1.00e+00	3.918	1	1	36
GO:0030433	ER-associated ubiquitin-dependent protein catabolic process	6.42e-02	1.00e+00	3.918	1	1	36
GO:0001895	retina homeostasis	6.42e-02	1.00e+00	3.918	1	1	36
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	6.42e-02	1.00e+00	3.918	1	3	36
GO:0001102	RNA polymerase II activating transcription factor binding	6.59e-02	1.00e+00	3.878	1	1	37
GO:0051084	'de novo' posttranslational protein folding	6.59e-02	1.00e+00	3.878	1	2	37
GO:0005791	rough endoplasmic reticulum	6.59e-02	1.00e+00	3.878	1	1	37
GO:0007067	mitotic nuclear division	6.70e-02	1.00e+00	2.236	2	7	231
GO:0001568	blood vessel development	6.76e-02	1.00e+00	3.840	1	2	38
GO:0070527	platelet aggregation	6.76e-02	1.00e+00	3.840	1	1	38
GO:0050681	androgen receptor binding	6.76e-02	1.00e+00	3.840	1	2	38
GO:0030049	muscle filament sliding	6.76e-02	1.00e+00	3.840	1	2	38
GO:0045740	positive regulation of DNA replication	6.76e-02	1.00e+00	3.840	1	1	38
GO:0006412	translation	6.90e-02	1.00e+00	2.211	2	29	235
GO:0031490	chromatin DNA binding	6.93e-02	1.00e+00	3.802	1	1	39
GO:0060048	cardiac muscle contraction	6.93e-02	1.00e+00	3.802	1	1	39
GO:0001933	negative regulation of protein phosphorylation	6.93e-02	1.00e+00	3.802	1	1	39
GO:0048471	perinuclear region of cytoplasm	7.01e-02	1.00e+00	1.642	3	9	523
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	7.10e-02	1.00e+00	3.766	1	1	40
GO:0007015	actin filament organization	7.10e-02	1.00e+00	3.766	1	1	40
GO:0030425	dendrite	7.16e-02	1.00e+00	2.181	2	3	240
GO:0051117	ATPase binding	7.27e-02	1.00e+00	3.730	1	2	41
GO:0008307	structural constituent of muscle	7.27e-02	1.00e+00	3.730	1	1	41
GO:0017148	negative regulation of translation	7.27e-02	1.00e+00	3.730	1	1	41
GO:0030521	androgen receptor signaling pathway	7.27e-02	1.00e+00	3.730	1	3	41
GO:0050885	neuromuscular process controlling balance	7.27e-02	1.00e+00	3.730	1	1	41
GO:0021987	cerebral cortex development	7.45e-02	1.00e+00	3.695	1	1	42
GO:0030155	regulation of cell adhesion	7.45e-02	1.00e+00	3.695	1	1	42
GO:0035914	skeletal muscle cell differentiation	7.45e-02	1.00e+00	3.695	1	1	42
GO:0005871	kinesin complex	7.79e-02	1.00e+00	3.628	1	1	44
GO:0050896	response to stimulus	7.79e-02	1.00e+00	3.628	1	1	44
GO:0016328	lateral plasma membrane	8.13e-02	1.00e+00	3.564	1	3	46
GO:0043525	positive regulation of neuron apoptotic process	8.13e-02	1.00e+00	3.564	1	2	46
GO:0001047	core promoter binding	8.13e-02	1.00e+00	3.564	1	1	46
GO:0005884	actin filament	8.13e-02	1.00e+00	3.564	1	2	46
GO:0001947	heart looping	8.63e-02	1.00e+00	3.473	1	1	49
GO:0003743	translation initiation factor activity	8.63e-02	1.00e+00	3.473	1	5	49
GO:0034097	response to cytokine	8.80e-02	1.00e+00	3.444	1	1	50
GO:0001948	glycoprotein binding	8.80e-02	1.00e+00	3.444	1	2	50
GO:0003684	damaged DNA binding	8.97e-02	1.00e+00	3.415	1	2	51
GO:0045732	positive regulation of protein catabolic process	8.97e-02	1.00e+00	3.415	1	1	51
GO:0045454	cell redox homeostasis	9.14e-02	1.00e+00	3.387	1	1	52
GO:0034976	response to endoplasmic reticulum stress	9.14e-02	1.00e+00	3.387	1	1	52
GO:0016042	lipid catabolic process	9.14e-02	1.00e+00	3.387	1	2	52
GO:0006952	defense response	9.30e-02	1.00e+00	3.360	1	1	53
GO:0019900	kinase binding	9.47e-02	1.00e+00	3.333	1	3	54
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding	9.47e-02	1.00e+00	3.333	1	1	54
GO:0050680	negative regulation of epithelial cell proliferation	9.47e-02	1.00e+00	3.333	1	1	54
GO:0000226	microtubule cytoskeleton organization	9.64e-02	1.00e+00	3.306	1	1	55
GO:0046330	positive regulation of JNK cascade	9.64e-02	1.00e+00	3.306	1	1	55
GO:0006888	ER to Golgi vesicle-mediated transport	9.64e-02	1.00e+00	3.306	1	1	55
GO:0000932	cytoplasmic mRNA processing body	9.81e-02	1.00e+00	3.280	1	1	56
GO:0007264	small GTPase mediated signal transduction	9.89e-02	1.00e+00	1.908	2	7	290
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	9.97e-02	1.00e+00	3.255	1	1	57
GO:0012505	endomembrane system	9.97e-02	1.00e+00	3.255	1	1	57
GO:0005783	endoplasmic reticulum	1.00e-01	1.00e+00	1.420	3	6	610
GO:0051087	chaperone binding	1.03e-01	1.00e+00	3.205	1	1	59
GO:0045216	cell-cell junction organization	1.03e-01	1.00e+00	3.205	1	2	59
GO:0005840	ribosome	1.03e-01	1.00e+00	3.205	1	10	59
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	1.03e-01	1.00e+00	3.205	1	1	59
GO:0010976	positive regulation of neuron projection development	1.05e-01	1.00e+00	3.181	1	2	60
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	1.06e-01	1.00e+00	3.157	1	1	61
GO:0033138	positive regulation of peptidyl-serine phosphorylation	1.06e-01	1.00e+00	3.157	1	1	61
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	1.08e-01	1.00e+00	3.133	1	1	62
GO:0000776	kinetochore	1.10e-01	1.00e+00	3.110	1	3	63
GO:0032869	cellular response to insulin stimulus	1.11e-01	1.00e+00	3.088	1	2	64
GO:0005856	cytoskeleton	1.11e-01	1.00e+00	1.807	2	6	311
GO:0006469	negative regulation of protein kinase activity	1.13e-01	1.00e+00	3.065	1	1	65
GO:0071260	cellular response to mechanical stimulus	1.15e-01	1.00e+00	3.043	1	3	66
GO:0009636	response to toxic substance	1.15e-01	1.00e+00	3.043	1	1	66
GO:0031295	T cell costimulation	1.16e-01	1.00e+00	3.021	1	3	67
GO:0030141	secretory granule	1.16e-01	1.00e+00	3.021	1	2	67
GO:0019901	protein kinase binding	1.17e-01	1.00e+00	1.766	2	9	320
GO:0006338	chromatin remodeling	1.18e-01	1.00e+00	3.000	1	2	68
GO:0045666	positive regulation of neuron differentiation	1.18e-01	1.00e+00	3.000	1	1	68
GO:0050790	regulation of catalytic activity	1.19e-01	1.00e+00	2.979	1	1	69
GO:0006887	exocytosis	1.19e-01	1.00e+00	2.979	1	1	69
GO:0007411	axon guidance	1.21e-01	1.00e+00	1.734	2	3	327
GO:0035264	multicellular organism growth	1.21e-01	1.00e+00	2.958	1	1	70
GO:0005525	GTP binding	1.21e-01	1.00e+00	1.730	2	6	328
GO:0034329	cell junction assembly	1.23e-01	1.00e+00	2.938	1	2	71
GO:0042383	sarcolemma	1.23e-01	1.00e+00	2.938	1	2	71
GO:0043231	intracellular membrane-bounded organelle	1.24e-01	1.00e+00	1.713	2	3	332
GO:0003682	chromatin binding	1.25e-01	1.00e+00	1.704	2	4	334
GO:0000785	chromatin	1.26e-01	1.00e+00	2.898	1	2	73
GO:0005085	guanyl-nucleotide exchange factor activity	1.28e-01	1.00e+00	2.878	1	1	74
GO:0007265	Ras protein signal transduction	1.29e-01	1.00e+00	2.859	1	3	75
GO:0060070	canonical Wnt signaling pathway	1.29e-01	1.00e+00	2.859	1	2	75
GO:0044325	ion channel binding	1.32e-01	1.00e+00	2.821	1	3	77
GO:0008584	male gonad development	1.32e-01	1.00e+00	2.821	1	1	77
GO:0017137	Rab GTPase binding	1.34e-01	1.00e+00	2.802	1	1	78
GO:0071013	catalytic step 2 spliceosome	1.36e-01	1.00e+00	2.784	1	1	79
GO:0010629	negative regulation of gene expression	1.37e-01	1.00e+00	2.766	1	2	80
GO:0003723	RNA binding	1.38e-01	1.00e+00	1.616	2	10	355
GO:0015031	protein transport	1.39e-01	1.00e+00	1.608	2	4	357
GO:0030054	cell junction	1.39e-01	1.00e+00	1.612	2	4	356
GO:0045177	apical part of cell	1.40e-01	1.00e+00	2.730	1	1	82
GO:0030336	negative regulation of cell migration	1.42e-01	1.00e+00	2.713	1	2	83
GO:0007517	muscle organ development	1.42e-01	1.00e+00	2.713	1	1	83
GO:0043197	dendritic spine	1.42e-01	1.00e+00	2.713	1	2	83
GO:0005179	hormone activity	1.44e-01	1.00e+00	2.695	1	1	84
GO:0047485	protein N-terminus binding	1.47e-01	1.00e+00	2.661	1	1	86
GO:0005925	focal adhesion	1.48e-01	1.00e+00	1.556	2	23	370
GO:0007160	cell-matrix adhesion	1.50e-01	1.00e+00	2.628	1	1	88
GO:0032321	positive regulation of Rho GTPase activity	1.50e-01	1.00e+00	2.628	1	1	88
GO:0000922	spindle pole	1.55e-01	1.00e+00	2.580	1	5	91
GO:0018279	protein N-linked glycosylation via asparagine	1.55e-01	1.00e+00	2.580	1	1	91
GO:0006928	cellular component movement	1.56e-01	1.00e+00	2.564	1	4	92
GO:0016363	nuclear matrix	1.56e-01	1.00e+00	2.564	1	4	92
GO:0016605	PML body	1.56e-01	1.00e+00	2.564	1	2	92
GO:0042470	melanosome	1.56e-01	1.00e+00	2.564	1	2	92
GO:0003700	sequence-specific DNA binding transcription factor activity	1.57e-01	1.00e+00	1.126	3	9	748
GO:0051091	positive regulation of sequence-specific DNA binding transcription factor activity	1.58e-01	1.00e+00	2.548	1	1	93
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.59e-01	1.00e+00	2.533	1	7	94
GO:0051082	unfolded protein binding	1.61e-01	1.00e+00	2.518	1	1	95
GO:0030426	growth cone	1.64e-01	1.00e+00	2.488	1	3	97
GO:0004888	transmembrane signaling receptor activity	1.73e-01	1.00e+00	2.401	1	1	103
GO:0005096	GTPase activator activity	1.81e-01	1.00e+00	2.333	1	3	108
GO:0030496	midbody	1.82e-01	1.00e+00	2.319	1	4	109
GO:0005938	cell cortex	1.82e-01	1.00e+00	2.319	1	1	109
GO:0005815	microtubule organizing center	1.84e-01	1.00e+00	2.306	1	4	110
GO:0030529	ribonucleoprotein complex	1.90e-01	1.00e+00	2.255	1	8	114
GO:0005819	spindle	1.90e-01	1.00e+00	2.255	1	4	114
GO:0072562	blood microparticle	1.93e-01	1.00e+00	2.230	1	1	116
GO:0005802	trans-Golgi network	1.93e-01	1.00e+00	2.230	1	2	116
GO:0005635	nuclear envelope	1.93e-01	1.00e+00	2.230	1	2	116
GO:0032496	response to lipopolysaccharide	2.02e-01	1.00e+00	2.157	1	1	122
GO:0016192	vesicle-mediated transport	2.02e-01	1.00e+00	2.157	1	1	122
GO:0006325	chromatin organization	2.03e-01	1.00e+00	2.145	1	2	123
GO:0007568	aging	2.03e-01	1.00e+00	2.145	1	2	123
GO:0007050	cell cycle arrest	2.08e-01	1.00e+00	2.110	1	2	126
GO:0007596	blood coagulation	2.09e-01	1.00e+00	1.230	2	5	464
GO:0006511	ubiquitin-dependent protein catabolic process	2.09e-01	1.00e+00	2.099	1	3	127
GO:0008201	heparin binding	2.09e-01	1.00e+00	2.099	1	1	127
GO:0046983	protein dimerization activity	2.15e-01	1.00e+00	2.054	1	3	131
GO:0006413	translational initiation	2.15e-01	1.00e+00	2.054	1	27	131
GO:0042802	identical protein binding	2.28e-01	1.00e+00	1.148	2	4	491
GO:0007507	heart development	2.29e-01	1.00e+00	1.948	1	1	141
GO:0003735	structural constituent of ribosome	2.29e-01	1.00e+00	1.948	1	24	141
GO:0005911	cell-cell junction	2.31e-01	1.00e+00	1.938	1	2	142
GO:0008286	insulin receptor signaling pathway	2.34e-01	1.00e+00	1.918	1	4	144
GO:0010628	positive regulation of gene expression	2.41e-01	1.00e+00	1.868	1	4	149
GO:0008017	microtubule binding	2.42e-01	1.00e+00	1.859	1	2	150
GO:0001666	response to hypoxia	2.42e-01	1.00e+00	1.859	1	1	150
GO:0051260	protein homooligomerization	2.42e-01	1.00e+00	1.859	1	2	150
GO:0000082	G1/S transition of mitotic cell cycle	2.42e-01	1.00e+00	1.859	1	11	150
GO:0030246	carbohydrate binding	2.44e-01	1.00e+00	1.849	1	1	151
GO:0042981	regulation of apoptotic process	2.44e-01	1.00e+00	1.849	1	7	151
GO:0001077	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription	2.44e-01	1.00e+00	1.849	1	2	151
GO:0043005	neuron projection	2.57e-01	1.00e+00	1.757	1	6	161
GO:0016032	viral process	2.61e-01	1.00e+00	1.011	2	37	540
GO:0000398	mRNA splicing, via spliceosome	2.63e-01	1.00e+00	1.721	1	2	165
GO:0007601	visual perception	2.67e-01	1.00e+00	1.695	1	1	168
GO:0016607	nuclear speck	2.77e-01	1.00e+00	1.636	1	2	175
GO:0031965	nuclear membrane	2.78e-01	1.00e+00	1.628	1	2	176
GO:0007049	cell cycle	2.79e-01	1.00e+00	1.620	1	4	177
GO:0043687	post-translational protein modification	2.85e-01	1.00e+00	1.588	1	1	181
GO:0015629	actin cytoskeleton	2.87e-01	1.00e+00	1.572	1	3	183
GO:0005509	calcium ion binding	2.95e-01	1.00e+00	0.885	2	4	589
GO:0007173	epidermal growth factor receptor signaling pathway	2.98e-01	1.00e+00	1.510	1	5	191
GO:0045087	innate immune response	3.14e-01	1.00e+00	0.821	2	11	616
GO:0042803	protein homodimerization activity	3.14e-01	1.00e+00	0.818	2	4	617
GO:0030168	platelet activation	3.16e-01	1.00e+00	1.408	1	4	205
GO:0001701	in utero embryonic development	3.22e-01	1.00e+00	1.373	1	2	210
GO:0006351	transcription, DNA-templated	3.32e-01	1.00e+00	0.457	4	17	1585
GO:0003713	transcription coactivator activity	3.58e-01	1.00e+00	1.187	1	6	239
GO:0007399	nervous system development	3.65e-01	1.00e+00	1.151	1	1	245
GO:0005730	nucleolus	3.75e-01	1.00e+00	0.370	4	36	1684
GO:0005634	nucleus	3.91e-01	1.00e+00	0.172	10	66	4828
GO:0043065	positive regulation of apoptotic process	3.99e-01	1.00e+00	0.990	1	6	274
GO:0003779	actin binding	4.00e-01	1.00e+00	0.984	1	3	275
GO:0007283	spermatogenesis	4.01e-01	1.00e+00	0.979	1	2	276
GO:0030198	extracellular matrix organization	4.22e-01	1.00e+00	0.883	1	1	295
GO:0030154	cell differentiation	4.53e-01	1.00e+00	0.743	1	3	325
GO:0003677	DNA binding	4.57e-01	1.00e+00	0.273	3	14	1351
GO:0007268	synaptic transmission	4.81e-01	1.00e+00	0.624	1	1	353
GO:0009986	cell surface	5.45e-01	1.00e+00	0.366	1	1	422
GO:0045892	negative regulation of transcription, DNA-templated	5.46e-01	1.00e+00	0.360	1	2	424
GO:0006366	transcription from RNA polymerase II promoter	5.47e-01	1.00e+00	0.356	1	3	425
GO:0005615	extracellular space	5.62e-01	1.00e+00	0.107	2	3	1010
GO:0006468	protein phosphorylation	5.82e-01	1.00e+00	0.220	1	6	467
GO:0055114	oxidation-reduction process	5.93e-01	1.00e+00	0.178	1	2	481
GO:0045893	positive regulation of transcription, DNA-templated	5.97e-01	1.00e+00	0.160	1	8	487
GO:0005654	nucleoplasm	6.07e-01	1.00e+00	-0.009	2	26	1095
GO:0006355	regulation of transcription, DNA-templated	6.12e-01	1.00e+00	-0.021	2	10	1104
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	6.68e-01	1.00e+00	-0.115	1	9	589
GO:0005789	endoplasmic reticulum membrane	6.97e-01	1.00e+00	-0.225	1	3	636
GO:0010467	gene expression	7.15e-01	1.00e+00	-0.298	1	36	669
GO:0007165	signal transduction	8.35e-01	1.00e+00	-0.804	1	7	950
GO:0005887	integral component of plasma membrane	8.38e-01	1.00e+00	-0.821	1	2	961
GO:0008270	zinc ion binding	8.69e-01	1.00e+00	-0.972	1	7	1067
GO:0005524	ATP binding	9.26e-01	1.00e+00	-1.315	1	19	1354
GO:0046872	metal ion binding	9.41e-01	1.00e+00	-1.429	1	14	1465
GO:0016021	integral component of membrane	9.93e-01	1.00e+00	-2.190	1	4	2483

Tai-Luciferase

meta-int-snw-23433

Interacting subnets

Genes (30)

Interactions (64)

Related GO terms (524)