reg-snw-9921

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.335	5.59e-08	1.93e-02	1.56e-02

chia-screen-data-Fav-reg-snw-9921 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
POLR2L	5441	1	-1.972	2.335	17	TF	-	-
[ RNF10 ]	9921	1	-1.461	2.335	5	TF	-	-
PDZD11	51248	1	-2.457	2.335	2	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
NDUFB10	4716	1	-1.757	2.335	8	-	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
GPS1	2873	NDUFB10	4716	pd	>	reg.ITFP.txt: no annot
NDUFB10	4716	RNF10	9921	pd	<	reg.ITFP.txt: no annot
NDUFB10	4716	POLR2L	5441	pd	<	reg.ITFP.txt: no annot
POLR2L	5441	PDZD11	51248	pd	>	reg.ITFP.txt: no annot

Related GO terms (78)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0010626	negative regulation of Schwann cell proliferation	1.84e-03	1.00e+00	9.083	1	1	3
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	3.07e-03	1.00e+00	8.347	1	1	5
GO:0044212	transcription regulatory region DNA binding	3.07e-03	1.00e+00	4.509	2	13	143
GO:0006356	regulation of transcription from RNA polymerase I promoter	3.07e-03	1.00e+00	8.347	1	1	5
GO:0050847	progesterone receptor signaling pathway	3.68e-03	1.00e+00	8.083	1	2	6
GO:0001055	RNA polymerase II activity	3.68e-03	1.00e+00	8.083	1	3	6
GO:0031643	positive regulation of myelination	4.29e-03	1.00e+00	7.861	1	1	7
GO:0010944	negative regulation of transcription by competitive promoter binding	4.91e-03	1.00e+00	7.668	1	1	8
GO:0010388	cullin deneddylation	4.91e-03	1.00e+00	7.668	1	4	8
GO:0071354	cellular response to interleukin-6	5.52e-03	1.00e+00	7.499	1	1	9
GO:0005743	mitochondrial inner membrane	5.76e-03	1.00e+00	4.046	2	9	197
GO:0005736	DNA-directed RNA polymerase I complex	6.13e-03	1.00e+00	7.347	1	4	10
GO:0001054	RNA polymerase I activity	6.13e-03	1.00e+00	7.347	1	4	10
GO:0005095	GTPase inhibitor activity	6.13e-03	1.00e+00	7.347	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	6.74e-03	1.00e+00	7.209	1	4	11
GO:0005665	DNA-directed RNA polymerase II, core complex	7.96e-03	1.00e+00	6.968	1	3	13
GO:0001056	RNA polymerase III activity	7.96e-03	1.00e+00	6.968	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	7.96e-03	1.00e+00	6.968	1	3	13
GO:0006385	transcription elongation from RNA polymerase III promoter	8.57e-03	1.00e+00	6.861	1	3	14
GO:0006386	termination of RNA polymerase III transcription	8.57e-03	1.00e+00	6.861	1	3	14
GO:0016575	histone deacetylation	8.57e-03	1.00e+00	6.861	1	2	14
GO:0000188	inactivation of MAPK activity	9.18e-03	1.00e+00	6.762	1	1	15
GO:0003899	DNA-directed RNA polymerase activity	1.10e-02	1.00e+00	6.499	1	3	18
GO:0071897	DNA biosynthetic process	1.22e-02	1.00e+00	6.347	1	2	20
GO:0008180	COP9 signalosome	1.47e-02	1.00e+00	6.083	1	6	24
GO:0008137	NADH dehydrogenase (ubiquinone) activity	1.47e-02	1.00e+00	6.083	1	2	24
GO:0006370	7-methylguanosine mRNA capping	1.47e-02	1.00e+00	6.083	1	5	24
GO:0006120	mitochondrial electron transport, NADH to ubiquinone	1.53e-02	1.00e+00	6.025	1	2	25
GO:0005747	mitochondrial respiratory chain complex I	1.59e-02	1.00e+00	5.968	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	1.65e-02	1.00e+00	5.914	1	4	27
GO:0006383	transcription from RNA polymerase III promoter	1.77e-02	1.00e+00	5.810	1	6	29
GO:0051865	protein autoubiquitination	1.89e-02	1.00e+00	5.714	1	2	31
GO:0045893	positive regulation of transcription, DNA-templated	2.01e-02	1.00e+00	3.110	2	21	377
GO:0007254	JNK cascade	2.07e-02	1.00e+00	5.581	1	1	34
GO:0050434	positive regulation of viral transcription	2.13e-02	1.00e+00	5.539	1	5	35
GO:0006283	transcription-coupled nucleotide-excision repair	2.43e-02	1.00e+00	5.347	1	6	40
GO:0032481	positive regulation of type I interferon production	2.91e-02	1.00e+00	5.083	1	3	48
GO:0006368	transcription elongation from RNA polymerase II promoter	3.15e-02	1.00e+00	4.968	1	8	52
GO:0006289	nucleotide-excision repair	3.21e-02	1.00e+00	4.941	1	6	53
GO:0022904	respiratory electron transport chain	3.27e-02	1.00e+00	4.914	1	3	54
GO:0042826	histone deacetylase binding	3.51e-02	1.00e+00	4.810	1	5	58
GO:0030308	negative regulation of cell growth	4.23e-02	1.00e+00	4.539	1	3	70
GO:0001649	osteoblast differentiation	4.46e-02	1.00e+00	4.459	1	5	74
GO:0044237	cellular metabolic process	4.52e-02	1.00e+00	4.440	1	3	75
GO:0005737	cytoplasm	4.89e-02	1.00e+00	1.306	4	127	2633
GO:0005515	protein binding	5.22e-02	1.00e+00	0.981	5	198	4124
GO:0016323	basolateral plasma membrane	6.34e-02	1.00e+00	3.941	1	3	106
GO:0042981	regulation of apoptotic process	6.69e-02	1.00e+00	3.861	1	4	112
GO:0008270	zinc ion binding	6.79e-02	1.00e+00	2.163	2	39	727
GO:0008022	protein C-terminus binding	6.86e-02	1.00e+00	3.823	1	5	115
GO:0007049	cell cycle	6.86e-02	1.00e+00	3.823	1	8	115
GO:0000398	mRNA splicing, via spliceosome	7.61e-02	1.00e+00	3.668	1	15	128
GO:0005654	nucleoplasm	9.46e-02	1.00e+00	1.894	2	68	876
GO:0006367	transcription initiation from RNA polymerase II promoter	9.50e-02	1.00e+00	3.338	1	18	161
GO:0008380	RNA splicing	9.72e-02	1.00e+00	3.302	1	21	165
GO:0005634	nucleus	9.92e-02	1.00e+00	1.004	4	158	3246
GO:0004842	ubiquitin-protein transferase activity	1.05e-01	1.00e+00	3.185	1	17	179
GO:0006281	DNA repair	1.18e-01	1.00e+00	3.003	1	24	203
GO:0019899	enzyme binding	1.22e-01	1.00e+00	2.954	1	7	210
GO:0008285	negative regulation of cell proliferation	1.59e-01	1.00e+00	2.555	1	11	277
GO:0045892	negative regulation of transcription, DNA-templated	1.80e-01	1.00e+00	2.360	1	17	317
GO:0006366	transcription from RNA polymerase II promoter	1.92e-01	1.00e+00	2.255	1	23	341
GO:0016032	viral process	2.36e-01	1.00e+00	1.927	1	30	428
GO:0045087	innate immune response	2.48e-01	1.00e+00	1.848	1	12	452
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.49e-01	1.00e+00	1.836	1	29	456
GO:0070062	extracellular vesicular exosome	2.67e-01	1.00e+00	0.988	2	51	1641
GO:0010467	gene expression	2.87e-01	1.00e+00	1.605	1	49	535
GO:0005829	cytosol	3.03e-01	1.00e+00	0.865	2	88	1787
GO:0005887	integral component of plasma membrane	3.05e-01	1.00e+00	1.501	1	8	575
GO:0007165	signal transduction	3.25e-01	1.00e+00	1.397	1	24	618
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.36e-01	1.00e+00	1.338	1	29	644
GO:0005739	mitochondrion	3.43e-01	1.00e+00	1.304	1	32	659
GO:0005576	extracellular region	3.44e-01	1.00e+00	1.296	1	15	663
GO:0006355	regulation of transcription, DNA-templated	3.66e-01	1.00e+00	1.187	1	31	715
GO:0044281	small molecule metabolic process	4.19e-01	1.00e+00	0.947	1	35	844
GO:0003677	DNA binding	4.58e-01	1.00e+00	0.781	1	52	947
GO:0006351	transcription, DNA-templated	5.04e-01	1.00e+00	0.597	1	47	1076
GO:0016020	membrane	5.47e-01	1.00e+00	0.431	1	56	1207

chia-Fav

reg-snw-9921

Statistics

Genes (6)

Interactions (5)

Related GO terms (78)