reg-snw-8396

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.246	1.66e-07	3.51e-02	2.70e-02

chia-screen-data-Fav-reg-snw-8396 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
[ PIP4K2B ]	8396	1	-1.406	2.246	4	-	-	-
TPR	7175	10	-2.638	2.445	36	TF	Yes	Yes
NCBP1	4686	41	-2.510	2.459	44	-	Yes	Yes
RAPGEF2	9693	2	-1.892	2.246	11	-	-	-
SLC7A5P1	81893	4	-3.217	2.445	4	-	Yes	-
MED28	80306	8	-2.404	2.445	6	-	Yes	-
CASP2	835	4	-2.007	2.445	47	TF	Yes	-
CBLL1	79872	9	-1.897	2.445	38	TF	-	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NCBP1	4686	TPR	7175	pd	<	reg.ITFP.txt: no annot
CASP2	835	CBLL1	79872	pd	<>	reg.ITFP.txt: no annot
CASP2	835	SLC7A5P1	81893	pd	>	reg.ITFP.txt: no annot
NCBP1	4686	CBLL1	79872	pd	<	reg.ITFP.txt: no annot
CBLL1	79872	MED28	80306	pd	>	reg.ITFP.txt: no annot
CASP2	835	RAPGEF2	9693	pd	>	reg.ITFP.txt: no annot
CASP2	835	PIP4K2B	8396	pd	>	reg.ITFP.txt: no annot

Related GO terms (198)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0048022	negative regulation of melanin biosynthetic process	8.19e-04	1.00e+00	10.253	1	1	1
GO:1901673	regulation of spindle assembly involved in mitosis	8.19e-04	1.00e+00	10.253	1	1	1
GO:0043578	nuclear matrix organization	8.19e-04	1.00e+00	10.253	1	1	1
GO:0010965	regulation of mitotic sister chromatid separation	8.19e-04	1.00e+00	10.253	1	1	1
GO:0006404	RNA import into nucleus	8.19e-04	1.00e+00	10.253	1	1	1
GO:0031453	positive regulation of heterochromatin assembly	8.19e-04	1.00e+00	10.253	1	1	1
GO:0001554	luteolysis	8.19e-04	1.00e+00	10.253	1	1	1
GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0000189	MAPK import into nucleus	1.64e-03	1.00e+00	9.253	1	1	2
GO:1901888	regulation of cell junction assembly	1.64e-03	1.00e+00	9.253	1	1	2
GO:0031990	mRNA export from nucleus in response to heat stress	1.64e-03	1.00e+00	9.253	1	1	2
GO:0071880	adenylate cyclase-activating adrenergic receptor signaling pathway	1.64e-03	1.00e+00	9.253	1	1	2
GO:0042306	regulation of protein import into nucleus	1.64e-03	1.00e+00	9.253	1	1	2
GO:0005846	nuclear cap binding complex	1.64e-03	1.00e+00	9.253	1	1	2
GO:0070840	dynein complex binding	1.64e-03	1.00e+00	9.253	1	1	2
GO:0046832	negative regulation of RNA export from nucleus	1.64e-03	1.00e+00	9.253	1	1	2
GO:0031547	brain-derived neurotrophic factor receptor signaling pathway	1.64e-03	1.00e+00	9.253	1	1	2
GO:0050774	negative regulation of dendrite morphogenesis	2.46e-03	1.00e+00	8.668	1	1	3
GO:0046582	Rap GTPase activator activity	2.46e-03	1.00e+00	8.668	1	1	3
GO:0005088	Ras guanyl-nucleotide exchange factor activity	2.46e-03	1.00e+00	8.668	1	1	3
GO:2000670	positive regulation of dendritic cell apoptotic process	2.46e-03	1.00e+00	8.668	1	1	3
GO:0006405	RNA export from nucleus	2.46e-03	1.00e+00	8.668	1	1	3
GO:0017034	Rap guanyl-nucleotide exchange factor activity	2.46e-03	1.00e+00	8.668	1	1	3
GO:0010793	regulation of mRNA export from nucleus	2.46e-03	1.00e+00	8.668	1	1	3
GO:0031697	beta-1 adrenergic receptor binding	2.46e-03	1.00e+00	8.668	1	1	3
GO:0003407	neural retina development	3.27e-03	1.00e+00	8.253	1	2	4
GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity	3.27e-03	1.00e+00	8.253	1	1	4
GO:0051151	negative regulation of smooth muscle cell differentiation	3.27e-03	1.00e+00	8.253	1	1	4
GO:0045292	mRNA cis splicing, via spliceosome	3.27e-03	1.00e+00	8.253	1	1	4
GO:0031442	positive regulation of mRNA 3'-end processing	3.27e-03	1.00e+00	8.253	1	1	4
GO:2000481	positive regulation of cAMP-dependent protein kinase activity	3.27e-03	1.00e+00	8.253	1	1	4
GO:0006999	nuclear pore organization	3.27e-03	1.00e+00	8.253	1	1	4
GO:0070849	response to epidermal growth factor	3.27e-03	1.00e+00	8.253	1	1	4
GO:0044615	nuclear pore nuclear basket	3.27e-03	1.00e+00	8.253	1	1	4
GO:0038180	nerve growth factor signaling pathway	4.09e-03	1.00e+00	7.931	1	1	5
GO:0097153	cysteine-type endopeptidase activity involved in apoptotic process	4.09e-03	1.00e+00	7.931	1	1	5
GO:0046825	regulation of protein export from nucleus	4.09e-03	1.00e+00	7.931	1	1	5
GO:0043495	protein anchor	4.09e-03	1.00e+00	7.931	1	1	5
GO:0021884	forebrain neuron development	4.09e-03	1.00e+00	7.931	1	1	5
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	4.91e-03	1.00e+00	7.668	1	1	6
GO:0071321	cellular response to cGMP	4.91e-03	1.00e+00	7.668	1	1	6
GO:2001224	positive regulation of neuron migration	4.91e-03	1.00e+00	7.668	1	1	6
GO:0035234	ectopic germ cell programmed cell death	4.91e-03	1.00e+00	7.668	1	1	6
GO:0019992	diacylglycerol binding	4.91e-03	1.00e+00	7.668	1	1	6
GO:0032854	positive regulation of Rap GTPase activity	5.72e-03	1.00e+00	7.446	1	1	7
GO:2001214	positive regulation of vasculogenesis	5.72e-03	1.00e+00	7.446	1	2	7
GO:0000339	RNA cap binding	5.72e-03	1.00e+00	7.446	1	1	7
GO:0005868	cytoplasmic dynein complex	5.72e-03	1.00e+00	7.446	1	1	7
GO:0043281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	5.72e-03	1.00e+00	7.446	1	1	7
GO:0032486	Rap protein signal transduction	5.72e-03	1.00e+00	7.446	1	1	7
GO:0030553	cGMP binding	6.54e-03	1.00e+00	7.253	1	1	8
GO:0005845	mRNA cap binding complex	6.54e-03	1.00e+00	7.253	1	1	8
GO:0042405	nuclear inclusion body	6.54e-03	1.00e+00	7.253	1	1	8
GO:0051292	nuclear pore complex assembly	6.54e-03	1.00e+00	7.253	1	4	8
GO:0035457	cellular response to interferon-alpha	6.54e-03	1.00e+00	7.253	1	1	8
GO:0006379	mRNA cleavage	7.35e-03	1.00e+00	7.083	1	2	9
GO:0045947	negative regulation of translational initiation	7.35e-03	1.00e+00	7.083	1	1	9
GO:0021591	ventricular system development	7.35e-03	1.00e+00	7.083	1	1	9
GO:0061028	establishment of endothelial barrier	8.17e-03	1.00e+00	6.931	1	1	10
GO:0043950	positive regulation of cAMP-mediated signaling	8.98e-03	1.00e+00	6.794	1	1	11
GO:0051019	mitogen-activated protein kinase binding	8.98e-03	1.00e+00	6.794	1	1	11
GO:0008334	histone mRNA metabolic process	8.98e-03	1.00e+00	6.794	1	1	11
GO:0090316	positive regulation of intracellular protein transport	8.98e-03	1.00e+00	6.794	1	1	11
GO:0045807	positive regulation of endocytosis	8.98e-03	1.00e+00	6.794	1	1	11
GO:0005487	nucleocytoplasmic transporter activity	8.98e-03	1.00e+00	6.794	1	2	11
GO:1990090	cellular response to nerve growth factor stimulus	8.98e-03	1.00e+00	6.794	1	1	11
GO:0046827	positive regulation of protein export from nucleus	8.98e-03	1.00e+00	6.794	1	1	11
GO:0042307	positive regulation of protein import into nucleus	9.79e-03	1.00e+00	6.668	1	3	12
GO:0034399	nuclear periphery	9.79e-03	1.00e+00	6.668	1	3	12
GO:0035556	intracellular signal transduction	1.07e-02	1.00e+00	3.617	2	5	199
GO:0030552	cAMP binding	1.14e-02	1.00e+00	6.446	1	1	14
GO:0050699	WW domain binding	1.14e-02	1.00e+00	6.446	1	1	14
GO:0046854	phosphatidylinositol phosphorylation	1.22e-02	1.00e+00	6.347	1	1	15
GO:0097194	execution phase of apoptosis	1.22e-02	1.00e+00	6.347	1	1	15
GO:0030864	cortical actin cytoskeleton	1.30e-02	1.00e+00	6.253	1	1	16
GO:0016485	protein processing	1.30e-02	1.00e+00	6.253	1	1	16
GO:0019933	cAMP-mediated signaling	1.38e-02	1.00e+00	6.166	1	1	17
GO:0006611	protein export from nucleus	1.47e-02	1.00e+00	6.083	1	1	18
GO:0031047	gene silencing by RNA	1.47e-02	1.00e+00	6.083	1	2	18
GO:0032320	positive regulation of Ras GTPase activity	1.47e-02	1.00e+00	6.083	1	2	18
GO:2001235	positive regulation of apoptotic signaling pathway	1.55e-02	1.00e+00	6.005	1	2	19
GO:0015631	tubulin binding	1.63e-02	1.00e+00	5.931	1	1	20
GO:0072686	mitotic spindle	1.63e-02	1.00e+00	5.931	1	2	20
GO:0034660	ncRNA metabolic process	1.63e-02	1.00e+00	5.931	1	1	20
GO:0048167	regulation of synaptic plasticity	1.71e-02	1.00e+00	5.861	1	1	21
GO:0031647	regulation of protein stability	1.71e-02	1.00e+00	5.861	1	2	21
GO:0006606	protein import into nucleus	1.79e-02	1.00e+00	5.794	1	3	22
GO:0000387	spliceosomal snRNP assembly	1.79e-02	1.00e+00	5.794	1	1	22
GO:0034605	cellular response to heat	1.79e-02	1.00e+00	5.794	1	1	22
GO:0007162	negative regulation of cell adhesion	1.95e-02	1.00e+00	5.668	1	2	24
GO:0006370	7-methylguanosine mRNA capping	1.95e-02	1.00e+00	5.668	1	5	24
GO:0016592	mediator complex	2.03e-02	1.00e+00	5.610	1	6	25
GO:0010827	regulation of glucose transport	2.03e-02	1.00e+00	5.610	1	7	25
GO:0007094	mitotic spindle assembly checkpoint	2.03e-02	1.00e+00	5.610	1	4	25
GO:0005057	receptor signaling protein activity	2.11e-02	1.00e+00	5.553	1	2	26
GO:0031072	heat shock protein binding	2.27e-02	1.00e+00	5.446	1	1	28
GO:0006446	regulation of translational initiation	2.35e-02	1.00e+00	5.395	1	2	29
GO:0019898	extrinsic component of membrane	2.43e-02	1.00e+00	5.347	1	1	30
GO:0097192	extrinsic apoptotic signaling pathway in absence of ligand	2.51e-02	1.00e+00	5.299	1	1	31
GO:0001568	blood vessel development	2.51e-02	1.00e+00	5.299	1	1	31
GO:0007077	mitotic nuclear envelope disassembly	2.59e-02	1.00e+00	5.253	1	9	32
GO:0071320	cellular response to cAMP	2.67e-02	1.00e+00	5.209	1	1	33
GO:0032092	positive regulation of protein binding	2.75e-02	1.00e+00	5.166	1	2	34
GO:0050434	positive regulation of viral transcription	2.83e-02	1.00e+00	5.124	1	5	35
GO:0006661	phosphatidylinositol biosynthetic process	2.83e-02	1.00e+00	5.124	1	1	35
GO:0031124	mRNA 3'-end processing	2.83e-02	1.00e+00	5.124	1	4	35
GO:0008645	hexose transport	2.91e-02	1.00e+00	5.083	1	8	36
GO:0004197	cysteine-type endopeptidase activity	2.99e-02	1.00e+00	5.044	1	1	37
GO:0045860	positive regulation of protein kinase activity	2.99e-02	1.00e+00	5.044	1	2	37
GO:0006369	termination of RNA polymerase II transcription	3.07e-02	1.00e+00	5.005	1	5	38
GO:0010976	positive regulation of neuron projection development	3.15e-02	1.00e+00	4.968	1	1	39
GO:0019827	stem cell maintenance	3.15e-02	1.00e+00	4.968	1	4	39
GO:0043525	positive regulation of neuron apoptotic process	3.31e-02	1.00e+00	4.896	1	1	41
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	3.39e-02	1.00e+00	4.861	1	2	42
GO:0006406	mRNA export from nucleus	3.55e-02	1.00e+00	4.794	1	7	44
GO:0015758	glucose transport	3.87e-02	1.00e+00	4.668	1	8	48
GO:0000151	ubiquitin ligase complex	3.87e-02	1.00e+00	4.668	1	4	48
GO:0005643	nuclear pore	4.10e-02	1.00e+00	4.581	1	12	51
GO:0006368	transcription elongation from RNA polymerase II promoter	4.18e-02	1.00e+00	4.553	1	8	52
GO:0030165	PDZ domain binding	4.18e-02	1.00e+00	4.553	1	3	52
GO:0007218	neuropeptide signaling pathway	4.26e-02	1.00e+00	4.525	1	2	53
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	4.26e-02	1.00e+00	4.525	1	3	53
GO:0005770	late endosome	4.34e-02	1.00e+00	4.499	1	2	54
GO:0000776	kinetochore	4.42e-02	1.00e+00	4.472	1	8	55
GO:0071260	cellular response to mechanical stimulus	4.42e-02	1.00e+00	4.472	1	2	55
GO:0031175	neuron projection development	4.42e-02	1.00e+00	4.472	1	1	55
GO:0016032	viral process	4.50e-02	1.00e+00	2.512	2	30	428
GO:0003729	mRNA binding	4.58e-02	1.00e+00	4.421	1	4	57
GO:0000165	MAPK cascade	4.66e-02	1.00e+00	4.395	1	3	58
GO:0016337	single organismal cell-cell adhesion	4.97e-02	1.00e+00	4.299	1	3	62
GO:0001764	neuron migration	5.36e-02	1.00e+00	4.187	1	1	67
GO:0070374	positive regulation of ERK1 and ERK2 cascade	6.06e-02	1.00e+00	4.005	1	1	76
GO:0005515	protein binding	6.50e-02	1.00e+00	0.829	6	198	4124
GO:0030529	ribonucleoprotein complex	6.53e-02	1.00e+00	3.896	1	5	82
GO:0005215	transporter activity	6.53e-02	1.00e+00	3.896	1	5	82
GO:0016020	membrane	6.54e-02	1.00e+00	1.601	3	56	1207
GO:0097190	apoptotic signaling pathway	6.60e-02	1.00e+00	3.878	1	1	83
GO:0045202	synapse	6.60e-02	1.00e+00	3.878	1	3	83
GO:0005635	nuclear envelope	6.60e-02	1.00e+00	3.878	1	6	83
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.68e-02	1.00e+00	3.861	1	5	84
GO:0007166	cell surface receptor signaling pathway	7.07e-02	1.00e+00	3.778	1	3	89
GO:0006644	phospholipid metabolic process	7.07e-02	1.00e+00	3.778	1	1	89
GO:0007568	aging	7.68e-02	1.00e+00	3.653	1	3	97
GO:0030335	positive regulation of cell migration	7.98e-02	1.00e+00	3.595	1	2	101
GO:0005911	cell-cell junction	8.21e-02	1.00e+00	3.553	1	3	104
GO:0043005	neuron projection	8.89e-02	1.00e+00	3.433	1	6	113
GO:0007420	brain development	9.35e-02	1.00e+00	3.359	1	3	119
GO:0005739	mitochondrion	9.71e-02	1.00e+00	1.889	2	32	659
GO:0000398	mRNA splicing, via spliceosome	1.00e-01	1.00e+00	3.253	1	15	128
GO:0031965	nuclear membrane	1.02e-01	1.00e+00	3.231	1	8	130
GO:0019904	protein domain specific binding	1.02e-01	1.00e+00	3.231	1	4	130
GO:0016874	ligase activity	1.14e-01	1.00e+00	3.064	1	11	146
GO:0004871	signal transducer activity	1.15e-01	1.00e+00	3.044	1	4	148
GO:0008380	RNA splicing	1.27e-01	1.00e+00	2.887	1	21	165
GO:0007067	mitotic nuclear division	1.27e-01	1.00e+00	2.887	1	9	165
GO:0016071	mRNA metabolic process	1.31e-01	1.00e+00	2.844	1	10	170
GO:0043025	neuronal cell body	1.32e-01	1.00e+00	2.836	1	3	171
GO:0019221	cytokine-mediated signaling pathway	1.33e-01	1.00e+00	2.827	1	10	172
GO:0007264	small GTPase mediated signal transduction	1.34e-01	1.00e+00	2.810	1	8	174
GO:0044822	poly(A) RNA binding	1.35e-01	1.00e+00	1.611	2	45	799
GO:0004842	ubiquitin-protein transferase activity	1.38e-01	1.00e+00	2.770	1	17	179
GO:0003779	actin binding	1.38e-01	1.00e+00	2.770	1	3	179
GO:0005737	cytoplasm	1.43e-01	1.00e+00	0.891	4	127	2633
GO:0005975	carbohydrate metabolic process	1.43e-01	1.00e+00	2.714	1	10	186
GO:0016567	protein ubiquitination	1.44e-01	1.00e+00	2.699	1	14	188
GO:0016070	RNA metabolic process	1.44e-01	1.00e+00	2.699	1	10	188
GO:0044281	small molecule metabolic process	1.47e-01	1.00e+00	1.532	2	35	844
GO:0048011	neurotrophin TRK receptor signaling pathway	1.52e-01	1.00e+00	2.617	1	8	199
GO:0043065	positive regulation of apoptotic process	1.54e-01	1.00e+00	2.595	1	7	202
GO:0005654	nucleoplasm	1.57e-01	1.00e+00	1.479	2	68	876
GO:0043234	protein complex	1.60e-01	1.00e+00	2.539	1	13	210
GO:0019899	enzyme binding	1.60e-01	1.00e+00	2.539	1	7	210
GO:0005886	plasma membrane	1.66e-01	1.00e+00	1.037	3	46	1784
GO:0005829	cytosol	1.67e-01	1.00e+00	1.035	3	88	1787
GO:0007186	G-protein coupled receptor signaling pathway	1.73e-01	1.00e+00	2.414	1	4	229
GO:0019901	protein kinase binding	1.75e-01	1.00e+00	2.395	1	8	232
GO:0003723	RNA binding	1.85e-01	1.00e+00	2.305	1	22	247
GO:0003682	chromatin binding	1.89e-01	1.00e+00	2.276	1	15	252
GO:0006508	proteolysis	1.97e-01	1.00e+00	2.209	1	11	264
GO:0008285	negative regulation of cell proliferation	2.06e-01	1.00e+00	2.140	1	11	277
GO:0000278	mitotic cell cycle	2.30e-01	1.00e+00	1.959	1	28	314
GO:0055085	transmembrane transport	2.40e-01	1.00e+00	1.891	1	13	329
GO:0006366	transcription from RNA polymerase II promoter	2.48e-01	1.00e+00	1.840	1	23	341
GO:0048471	perinuclear region of cytoplasm	2.49e-01	1.00e+00	1.827	1	11	344
GO:0005509	calcium ion binding	2.54e-01	1.00e+00	1.798	1	9	351
GO:0042802	identical protein binding	2.56e-01	1.00e+00	1.786	1	15	354
GO:0005634	nucleus	2.57e-01	1.00e+00	0.589	4	158	3246
GO:0005789	endoplasmic reticulum membrane	2.76e-01	1.00e+00	1.657	1	7	387
GO:0006915	apoptotic process	2.91e-01	1.00e+00	1.570	1	15	411
GO:0042803	protein homodimerization activity	3.01e-01	1.00e+00	1.512	1	13	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.18e-01	1.00e+00	1.421	1	29	456
GO:0010467	gene expression	3.63e-01	1.00e+00	1.190	1	49	535
GO:0005887	integral component of plasma membrane	3.85e-01	1.00e+00	1.086	1	8	575
GO:0006355	regulation of transcription, DNA-templated	4.56e-01	1.00e+00	0.772	1	31	715
GO:0008270	zinc ion binding	4.62e-01	1.00e+00	0.748	1	39	727
GO:0005524	ATP binding	5.35e-01	1.00e+00	0.453	1	37	892
GO:0006351	transcription, DNA-templated	6.07e-01	1.00e+00	0.182	1	47	1076
GO:0005730	nucleolus	6.55e-01	1.00e+00	0.004	1	74	1217

chia-Fav

reg-snw-8396

Statistics

Genes (8)

Interactions (7)

Related GO terms (198)