reg-snw-57541

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.192	3.17e-07	4.92e-02	3.73e-02

chia-screen-data-Fav-reg-snw-57541 subnetwork

Genes (14)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RNF40	9810	10	-2.082	2.492	38	TF	Yes	-
KARS	3735	12	-1.759	2.428	123	TF	-	-
OTUB1	55611	4	-1.774	2.268	45	-	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
KLC3	147700	7	-2.130	2.290	132	TF	Yes	-
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
LCE1E	353135	7	-2.428	2.414	31	-	Yes	Yes
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
EIF3B	8662	1	-1.392	2.192	50	-	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
DRG2	1819	15	-2.526	2.492	11	-	Yes	-
SYMPK	8189	11	-1.890	2.492	51	TF	-	-
[ ZNF398 ]	57541	1	-1.193	2.192	11	TF	-	-

Interactions (15)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DRG2	1819	SYMPK	8189	pd	<	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
SYMPK	8189	OTUB1	55611	pd	>	reg.ITFP.txt: no annot
RNF40	9810	KLC3	147700	pd	<>	reg.ITFP.txt: no annot
VARS	7407	EIF3B	8662	pd	>	reg.ITFP.txt: no annot
RNF40	9810	ZNF398	57541	pd	<>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
SYMPK	8189	RNF40	9810	pd	<>	reg.ITFP.txt: no annot
EIF3B	8662	ZNF398	57541	pd	<	reg.ITFP.txt: no annot
RNF40	9810	OTUB1	55611	pd	>	reg.ITFP.txt: no annot
KLC3	147700	LCE1E	353135	pd	>	reg.ITFP.txt: no annot
KARS	3735	PHB	5245	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	KARS	3735	pd	<	reg.ITFP.txt: no annot
KARS	3735	EIF3B	8662	pd	>	reg.ITFP.txt: no annot

Related GO terms (123)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0006418	tRNA aminoacylation for protein translation	7.58e-04	1.00e+00	5.588	2	4	29
GO:0004832	valine-tRNA ligase activity	1.43e-03	1.00e+00	9.446	1	1	1
GO:0006430	lysyl-tRNA aminoacylation	1.43e-03	1.00e+00	9.446	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.43e-03	1.00e+00	9.446	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.43e-03	1.00e+00	9.446	1	1	1
GO:0004824	lysine-tRNA ligase activity	1.43e-03	1.00e+00	9.446	1	1	1
GO:0008175	tRNA methyltransferase activity	1.43e-03	1.00e+00	9.446	1	1	1
GO:0015966	diadenosine tetraphosphate biosynthetic process	2.87e-03	1.00e+00	8.446	1	1	2
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	2.87e-03	1.00e+00	8.446	1	1	2
GO:0019784	NEDD8-specific protease activity	2.87e-03	1.00e+00	8.446	1	1	2
GO:0003747	translation release factor activity	2.87e-03	1.00e+00	8.446	1	2	2
GO:1901315	negative regulation of histone H2A K63-linked ubiquitination	4.30e-03	1.00e+00	7.861	1	2	3
GO:0033503	HULC complex	5.72e-03	1.00e+00	7.446	1	1	4
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	7.15e-03	1.00e+00	7.124	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	7.15e-03	1.00e+00	7.124	1	1	5
GO:2000780	negative regulation of double-strand break repair	7.15e-03	1.00e+00	7.124	1	2	5
GO:0050847	progesterone receptor signaling pathway	8.57e-03	1.00e+00	6.861	1	2	6
GO:0002181	cytoplasmic translation	8.57e-03	1.00e+00	6.861	1	1	6
GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m	1.00e-02	1.00e+00	6.639	1	1	7
GO:0033523	histone H2B ubiquitination	1.00e-02	1.00e+00	6.639	1	1	7
GO:0043005	neuron projection	1.10e-02	1.00e+00	3.626	2	6	113
GO:0010944	negative regulation of transcription by competitive promoter binding	1.14e-02	1.00e+00	6.446	1	1	8
GO:0008088	axon cargo transport	1.14e-02	1.00e+00	6.446	1	1	8
GO:0010388	cullin deneddylation	1.14e-02	1.00e+00	6.446	1	4	8
GO:0008242	omega peptidase activity	1.14e-02	1.00e+00	6.446	1	1	8
GO:0010390	histone monoubiquitination	1.14e-02	1.00e+00	6.446	1	2	8
GO:0006450	regulation of translational fidelity	1.14e-02	1.00e+00	6.446	1	1	8
GO:0005739	mitochondrion	1.19e-02	1.00e+00	2.082	4	32	659
GO:0071354	cellular response to interleukin-6	1.28e-02	1.00e+00	6.276	1	1	9
GO:0035253	ciliary rootlet	1.28e-02	1.00e+00	6.276	1	1	9
GO:0005095	GTPase inhibitor activity	1.43e-02	1.00e+00	6.124	1	1	10
GO:0035307	positive regulation of protein dephosphorylation	1.43e-02	1.00e+00	6.124	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.57e-02	1.00e+00	5.987	1	4	11
GO:0033290	eukaryotic 48S preinitiation complex	1.57e-02	1.00e+00	5.987	1	1	11
GO:0006479	protein methylation	1.57e-02	1.00e+00	5.987	1	2	11
GO:0016282	eukaryotic 43S preinitiation complex	1.57e-02	1.00e+00	5.987	1	1	11
GO:0031625	ubiquitin protein ligase binding	1.61e-02	1.00e+00	3.338	2	7	138
GO:0005737	cytoplasm	1.65e-02	1.00e+00	1.084	8	127	2633
GO:0031369	translation initiation factor binding	1.85e-02	1.00e+00	5.746	1	1	13
GO:0071108	protein K48-linked deubiquitination	1.85e-02	1.00e+00	5.746	1	1	13
GO:0017075	syntaxin-1 binding	1.85e-02	1.00e+00	5.746	1	1	13
GO:0005852	eukaryotic translation initiation factor 3 complex	1.85e-02	1.00e+00	5.746	1	1	13
GO:0016597	amino acid binding	1.99e-02	1.00e+00	5.639	1	1	14
GO:0016575	histone deacetylation	1.99e-02	1.00e+00	5.639	1	2	14
GO:0031514	motile cilium	1.99e-02	1.00e+00	5.639	1	1	14
GO:0001731	formation of translation preinitiation complex	1.99e-02	1.00e+00	5.639	1	3	14
GO:0000188	inactivation of MAPK activity	2.13e-02	1.00e+00	5.539	1	1	15
GO:0006378	mRNA polyadenylation	2.55e-02	1.00e+00	5.276	1	3	18
GO:0032947	protein complex scaffold	2.83e-02	1.00e+00	5.124	1	2	20
GO:0071897	DNA biosynthetic process	2.83e-02	1.00e+00	5.124	1	2	20
GO:0019894	kinesin binding	2.97e-02	1.00e+00	5.054	1	1	21
GO:0005525	GTP binding	3.14e-02	1.00e+00	2.824	2	12	197
GO:0031424	keratinization	3.25e-02	1.00e+00	4.922	1	2	23
GO:0000049	tRNA binding	3.25e-02	1.00e+00	4.922	1	2	23
GO:0002376	immune system process	3.25e-02	1.00e+00	4.922	1	2	23
GO:0008180	COP9 signalosome	3.39e-02	1.00e+00	4.861	1	6	24
GO:0008033	tRNA processing	3.53e-02	1.00e+00	4.802	1	2	25
GO:0010467	gene expression	3.79e-02	1.00e+00	1.968	3	49	535
GO:0006446	regulation of translational initiation	4.08e-02	1.00e+00	4.588	1	2	29
GO:0043130	ubiquitin binding	4.22e-02	1.00e+00	4.539	1	3	30
GO:0005871	kinesin complex	4.36e-02	1.00e+00	4.492	1	3	31
GO:0007254	JNK cascade	4.77e-02	1.00e+00	4.359	1	1	34
GO:0003743	translation initiation factor activity	5.18e-02	1.00e+00	4.237	1	8	37
GO:0003777	microtubule motor activity	5.45e-02	1.00e+00	4.161	1	3	39
GO:0004843	ubiquitin-specific protease activity	6.40e-02	1.00e+00	3.922	1	2	46
GO:0000151	ubiquitin ligase complex	6.67e-02	1.00e+00	3.861	1	4	48
GO:0042826	histone deacetylase binding	8.01e-02	1.00e+00	3.588	1	5	58
GO:0006415	translational termination	8.67e-02	1.00e+00	3.469	1	2	63
GO:0005923	tight junction	8.80e-02	1.00e+00	3.446	1	2	64
GO:0030308	negative regulation of cell growth	9.59e-02	1.00e+00	3.317	1	3	70
GO:0045893	positive regulation of transcription, DNA-templated	9.97e-02	1.00e+00	1.888	2	21	377
GO:0001649	osteoblast differentiation	1.01e-01	1.00e+00	3.237	1	5	74
GO:0015630	microtubule cytoskeleton	1.02e-01	1.00e+00	3.217	1	5	75
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.14e-01	1.00e+00	3.054	1	5	84
GO:0006511	ubiquitin-dependent protein catabolic process	1.24e-01	1.00e+00	2.922	1	6	92
GO:0008017	microtubule binding	1.31e-01	1.00e+00	2.846	1	9	97
GO:0006413	translational initiation	1.33e-01	1.00e+00	2.817	1	6	99
GO:0042981	regulation of apoptotic process	1.49e-01	1.00e+00	2.639	1	4	112
GO:0007049	cell cycle	1.53e-01	1.00e+00	2.601	1	8	115
GO:0003924	GTPase activity	1.58e-01	1.00e+00	2.551	1	7	119
GO:0006974	cellular response to DNA damage stimulus	1.60e-01	1.00e+00	2.527	1	11	121
GO:0000082	G1/S transition of mitotic cell cycle	1.65e-01	1.00e+00	2.480	1	4	125
GO:0006184	GTP catabolic process	1.71e-01	1.00e+00	2.424	1	7	130
GO:0032403	protein complex binding	1.71e-01	1.00e+00	2.424	1	5	130
GO:0005759	mitochondrial matrix	1.82e-01	1.00e+00	2.327	1	7	139
GO:0044212	transcription regulatory region DNA binding	1.87e-01	1.00e+00	2.286	1	13	143
GO:0005622	intracellular	1.89e-01	1.00e+00	2.266	1	2	145
GO:0016874	ligase activity	1.90e-01	1.00e+00	2.256	1	11	146
GO:0005515	protein binding	1.94e-01	1.00e+00	0.436	8	198	4124
GO:0005874	microtubule	2.10e-01	1.00e+00	2.097	1	10	163
GO:0007165	signal transduction	2.21e-01	1.00e+00	1.175	2	24	618
GO:0000166	nucleotide binding	2.25e-01	1.00e+00	1.987	1	13	176
GO:0006412	translation	2.27e-01	1.00e+00	1.970	1	12	178
GO:0004842	ubiquitin-protein transferase activity	2.28e-01	1.00e+00	1.962	1	17	179
GO:0008152	metabolic process	2.32e-01	1.00e+00	1.938	1	6	182
GO:0005856	cytoskeleton	2.41e-01	1.00e+00	1.876	1	8	190
GO:0016020	membrane	2.45e-01	1.00e+00	0.794	3	56	1207
GO:0005743	mitochondrial inner membrane	2.48e-01	1.00e+00	1.824	1	9	197
GO:0006281	DNA repair	2.55e-01	1.00e+00	1.781	1	24	203
GO:0019899	enzyme binding	2.63e-01	1.00e+00	1.732	1	7	210
GO:0006355	regulation of transcription, DNA-templated	2.74e-01	1.00e+00	0.964	2	31	715
GO:0007155	cell adhesion	2.98e-01	1.00e+00	1.515	1	8	244
GO:0005634	nucleus	3.07e-01	1.00e+00	0.367	6	158	3246
GO:0006508	proteolysis	3.19e-01	1.00e+00	1.402	1	11	264
GO:0008285	negative regulation of cell proliferation	3.32e-01	1.00e+00	1.332	1	11	277
GO:0005654	nucleoplasm	3.62e-01	1.00e+00	0.671	2	68	876
GO:0005524	ATP binding	3.70e-01	1.00e+00	0.645	2	37	892
GO:0045892	negative regulation of transcription, DNA-templated	3.70e-01	1.00e+00	1.138	1	17	317
GO:0046872	metal ion binding	3.93e-01	1.00e+00	0.579	2	24	934
GO:0044267	cellular protein metabolic process	4.02e-01	1.00e+00	0.987	1	14	352
GO:0070062	extracellular vesicular exosome	4.26e-01	1.00e+00	0.351	3	51	1641
GO:0042803	protein homodimerization activity	4.66e-01	1.00e+00	0.705	1	13	428
GO:0016032	viral process	4.66e-01	1.00e+00	0.705	1	30	428
GO:0005829	cytosol	4.86e-01	1.00e+00	0.228	3	88	1787
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.88e-01	1.00e+00	0.613	1	29	456
GO:0005887	integral component of plasma membrane	5.73e-01	1.00e+00	0.279	1	8	575
GO:0005576	extracellular region	6.27e-01	1.00e+00	0.073	1	15	663
GO:0008270	zinc ion binding	6.62e-01	1.00e+00	-0.060	1	39	727
GO:0044822	poly(A) RNA binding	6.98e-01	1.00e+00	-0.196	1	45	799
GO:0005886	plasma membrane	7.55e-01	1.00e+00	-0.355	2	46	1784
GO:0003677	DNA binding	7.60e-01	1.00e+00	-0.441	1	52	947
GO:0006351	transcription, DNA-templated	8.05e-01	1.00e+00	-0.625	1	47	1076
GO:0005730	nucleolus	8.45e-01	1.00e+00	-0.803	1	74	1217

chia-Fav

reg-snw-57541

Statistics

Genes (14)

Interactions (15)

Related GO terms (123)