reg-snw-55611

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.268	1.27e-07	3.04e-02	2.37e-02

chia-screen-data-Fav-reg-snw-55611 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RNF40	9810	10	-2.082	2.492	38	TF	Yes	-
[ OTUB1 ]	55611	4	-1.774	2.268	45	-	-	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
RHOA	387	17	-2.408	2.644	10	-	Yes	Yes
HNRNPU	3192	39	-2.869	2.644	33	-	Yes	-
SYMPK	8189	11	-1.890	2.492	51	TF	-	-
DRG2	1819	15	-2.526	2.492	11	-	Yes	-
POLR2E	5434	30	-2.037	2.644	201	TF	Yes	-
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes

Interactions (10)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DRG2	1819	SYMPK	8189	pd	<	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
POLR2E	5434	VARS	7407	pd	<>	reg.ITFP.txt: no annot
SYMPK	8189	OTUB1	55611	pd	>	reg.ITFP.txt: no annot
RHOA	387	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
SYMPK	8189	RNF40	9810	pd	<>	reg.ITFP.txt: no annot
POLR2E	5434	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
RNF40	9810	OTUB1	55611	pd	>	reg.ITFP.txt: no annot
HNRNPU	3192	POLR2E	5434	pd	<	reg.ITFP.txt: no annot
POLR2E	5434	OTUB1	55611	pd	>	reg.ITFP.txt: no annot

Related GO terms (123)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0004832	valine-tRNA ligase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0061383	trabecula morphogenesis	9.22e-04	1.00e+00	10.083	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006438	valyl-tRNA aminoacylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0008175	tRNA methyltransferase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0033688	regulation of osteoblast proliferation	1.84e-03	1.00e+00	9.083	1	1	2
GO:0019784	NEDD8-specific protease activity	1.84e-03	1.00e+00	9.083	1	1	2
GO:1901315	negative regulation of histone H2A K63-linked ubiquitination	2.76e-03	1.00e+00	8.499	1	2	3
GO:0033503	HULC complex	3.68e-03	1.00e+00	8.083	1	1	4
GO:0036089	cleavage furrow formation	3.68e-03	1.00e+00	8.083	1	1	4
GO:0002161	aminoacyl-tRNA editing activity	4.60e-03	1.00e+00	7.762	1	1	5
GO:2000780	negative regulation of double-strand break repair	4.60e-03	1.00e+00	7.762	1	2	5
GO:0070934	CRD-mediated mRNA stabilization	4.60e-03	1.00e+00	7.762	1	2	5
GO:0038027	apolipoprotein A-I-mediated signaling pathway	4.60e-03	1.00e+00	7.762	1	1	5
GO:0043931	ossification involved in bone maturation	4.60e-03	1.00e+00	7.762	1	1	5
GO:0002181	cytoplasmic translation	5.52e-03	1.00e+00	7.499	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	5.52e-03	1.00e+00	7.499	1	2	6
GO:0001055	RNA polymerase II activity	5.52e-03	1.00e+00	7.499	1	3	6
GO:0043297	apical junction assembly	5.52e-03	1.00e+00	7.499	1	1	6
GO:0000398	mRNA splicing, via spliceosome	5.78e-03	1.00e+00	4.083	2	15	128
GO:0033523	histone H2B ubiquitination	6.44e-03	1.00e+00	7.276	1	1	7
GO:0031625	ubiquitin protein ligase binding	6.69e-03	1.00e+00	3.975	2	7	138
GO:0090307	spindle assembly involved in mitosis	7.35e-03	1.00e+00	7.083	1	2	8
GO:0008242	omega peptidase activity	7.35e-03	1.00e+00	7.083	1	1	8
GO:0010390	histone monoubiquitination	7.35e-03	1.00e+00	7.083	1	2	8
GO:0006450	regulation of translational fidelity	7.35e-03	1.00e+00	7.083	1	1	8
GO:0043296	apical junction complex	7.35e-03	1.00e+00	7.083	1	1	8
GO:0005736	DNA-directed RNA polymerase I complex	9.18e-03	1.00e+00	6.762	1	4	10
GO:0001054	RNA polymerase I activity	9.18e-03	1.00e+00	6.762	1	4	10
GO:0035307	positive regulation of protein dephosphorylation	9.18e-03	1.00e+00	6.762	1	1	10
GO:0050919	negative chemotaxis	9.18e-03	1.00e+00	6.762	1	1	10
GO:0008380	RNA splicing	9.45e-03	1.00e+00	3.717	2	21	165
GO:0010467	gene expression	1.07e-02	1.00e+00	2.605	3	49	535
GO:0005665	DNA-directed RNA polymerase II, core complex	1.19e-02	1.00e+00	6.383	1	3	13
GO:0001056	RNA polymerase III activity	1.19e-02	1.00e+00	6.383	1	3	13
GO:0071108	protein K48-linked deubiquitination	1.19e-02	1.00e+00	6.383	1	1	13
GO:0017075	syntaxin-1 binding	1.19e-02	1.00e+00	6.383	1	1	13
GO:0050772	positive regulation of axonogenesis	1.19e-02	1.00e+00	6.383	1	2	13
GO:0050770	regulation of axonogenesis	1.19e-02	1.00e+00	6.383	1	3	13
GO:0005666	DNA-directed RNA polymerase III complex	1.19e-02	1.00e+00	6.383	1	3	13
GO:0042346	positive regulation of NF-kappaB import into nucleus	1.19e-02	1.00e+00	6.383	1	1	13
GO:0005856	cytoskeleton	1.24e-02	1.00e+00	3.514	2	8	190
GO:0006385	transcription elongation from RNA polymerase III promoter	1.28e-02	1.00e+00	6.276	1	3	14
GO:0006386	termination of RNA polymerase III transcription	1.28e-02	1.00e+00	6.276	1	3	14
GO:0050771	negative regulation of axonogenesis	1.28e-02	1.00e+00	6.276	1	2	14
GO:0005525	GTP binding	1.33e-02	1.00e+00	3.461	2	12	197
GO:0006281	DNA repair	1.41e-02	1.00e+00	3.418	2	24	203
GO:0032467	positive regulation of cytokinesis	1.47e-02	1.00e+00	6.083	1	1	16
GO:0017022	myosin binding	1.47e-02	1.00e+00	6.083	1	2	16
GO:0003899	DNA-directed RNA polymerase activity	1.65e-02	1.00e+00	5.914	1	3	18
GO:0006378	mRNA polyadenylation	1.65e-02	1.00e+00	5.914	1	3	18
GO:0036464	cytoplasmic ribonucleoprotein granule	1.74e-02	1.00e+00	5.836	1	1	19
GO:0002376	immune system process	2.10e-02	1.00e+00	5.560	1	2	23
GO:0006370	7-methylguanosine mRNA capping	2.19e-02	1.00e+00	5.499	1	5	24
GO:0051496	positive regulation of stress fiber assembly	2.37e-02	1.00e+00	5.383	1	2	26
GO:0006360	transcription from RNA polymerase I promoter	2.46e-02	1.00e+00	5.329	1	4	27
GO:0006418	tRNA aminoacylation for protein translation	2.64e-02	1.00e+00	5.225	1	4	29
GO:0006383	transcription from RNA polymerase III promoter	2.64e-02	1.00e+00	5.225	1	6	29
GO:0043130	ubiquitin binding	2.73e-02	1.00e+00	5.177	1	3	30
GO:0032154	cleavage furrow	2.73e-02	1.00e+00	5.177	1	3	30
GO:0021762	substantia nigra development	3.09e-02	1.00e+00	4.996	1	1	34
GO:0007266	Rho protein signal transduction	3.18e-02	1.00e+00	4.954	1	2	35
GO:0050434	positive regulation of viral transcription	3.18e-02	1.00e+00	4.954	1	5	35
GO:0030334	regulation of cell migration	3.27e-02	1.00e+00	4.914	1	2	36
GO:0006396	RNA processing	3.63e-02	1.00e+00	4.762	1	4	40
GO:0006283	transcription-coupled nucleotide-excision repair	3.63e-02	1.00e+00	4.762	1	6	40
GO:0005654	nucleoplasm	4.01e-02	1.00e+00	1.894	3	68	876
GO:0004843	ubiquitin-specific protease activity	4.16e-02	1.00e+00	4.560	1	2	46
GO:0032481	positive regulation of type I interferon production	4.34e-02	1.00e+00	4.499	1	3	48
GO:0000151	ubiquitin ligase complex	4.34e-02	1.00e+00	4.499	1	4	48
GO:0006368	transcription elongation from RNA polymerase II promoter	4.69e-02	1.00e+00	4.383	1	8	52
GO:0045666	positive regulation of neuron differentiation	4.78e-02	1.00e+00	4.356	1	3	53
GO:0006289	nucleotide-excision repair	4.78e-02	1.00e+00	4.356	1	6	53
GO:0071013	catalytic step 2 spliceosome	5.49e-02	1.00e+00	4.153	1	5	61
GO:0016032	viral process	5.63e-02	1.00e+00	2.342	2	30	428
GO:0005923	tight junction	5.75e-02	1.00e+00	4.083	1	2	64
GO:0030496	midbody	6.53e-02	1.00e+00	3.894	1	6	73
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	5	74
GO:0051056	regulation of small GTPase mediated signal transduction	6.79e-02	1.00e+00	3.836	1	2	76
GO:0005938	cell cortex	6.88e-02	1.00e+00	3.817	1	6	77
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	5	82
GO:0048015	phosphatidylinositol-mediated signaling	7.40e-02	1.00e+00	3.708	1	2	83
GO:0030027	lamellipodium	7.83e-02	1.00e+00	3.624	1	3	88
GO:0030036	actin cytoskeleton organization	8.00e-02	1.00e+00	3.592	1	4	90
GO:0006511	ubiquitin-dependent protein catabolic process	8.17e-02	1.00e+00	3.560	1	6	92
GO:0016020	membrane	8.94e-02	1.00e+00	1.431	3	56	1207
GO:0007179	transforming growth factor beta receptor signaling pathway	9.44e-02	1.00e+00	3.342	1	5	107
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	9.53e-02	1.00e+00	3.329	1	2	108
GO:0043005	neuron projection	9.95e-02	1.00e+00	3.263	1	6	113
GO:0003924	GTPase activity	1.05e-01	1.00e+00	3.189	1	7	119
GO:0006974	cellular response to DNA damage stimulus	1.06e-01	1.00e+00	3.165	1	11	121
GO:0006184	GTP catabolic process	1.14e-01	1.00e+00	3.061	1	7	130
GO:0032403	protein complex binding	1.14e-01	1.00e+00	3.061	1	5	130
GO:0005739	mitochondrion	1.19e-01	1.00e+00	1.719	2	32	659
GO:0030168	platelet activation	1.23e-01	1.00e+00	2.944	1	5	141
GO:0005515	protein binding	1.26e-01	1.00e+00	0.659	6	198	4124
GO:0016874	ligase activity	1.27e-01	1.00e+00	2.894	1	11	146
GO:0006367	transcription initiation from RNA polymerase II promoter	1.39e-01	1.00e+00	2.753	1	18	161
GO:0007264	small GTPase mediated signal transduction	1.49e-01	1.00e+00	2.641	1	8	174
GO:0004842	ubiquitin-protein transferase activity	1.53e-01	1.00e+00	2.600	1	17	179
GO:0048011	neurotrophin TRK receptor signaling pathway	1.69e-01	1.00e+00	2.447	1	8	199
GO:0030054	cell junction	1.84e-01	1.00e+00	2.315	1	5	218
GO:0005524	ATP binding	1.96e-01	1.00e+00	1.283	2	37	892
GO:0007411	axon guidance	1.98e-01	1.00e+00	2.195	1	8	237
GO:0005737	cytoplasm	2.04e-01	1.00e+00	0.721	4	127	2633
GO:0007155	cell adhesion	2.04e-01	1.00e+00	2.153	1	8	244
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	22	247
GO:0003677	DNA binding	2.15e-01	1.00e+00	1.196	2	52	947
GO:0005829	cytosol	2.18e-01	1.00e+00	0.865	3	88	1787
GO:0006508	proteolysis	2.19e-01	1.00e+00	2.039	1	11	264
GO:0005925	focal adhesion	2.32e-01	1.00e+00	1.944	1	14	282
GO:0009986	cell surface	2.38e-01	1.00e+00	1.899	1	5	291
GO:0007596	blood coagulation	2.72e-01	1.00e+00	1.678	1	13	339
GO:0006366	transcription from RNA polymerase II promoter	2.74e-01	1.00e+00	1.670	1	23	341
GO:0042803	protein homodimerization activity	3.32e-01	1.00e+00	1.342	1	13	428
GO:0045087	innate immune response	3.47e-01	1.00e+00	1.263	1	12	452
GO:0005634	nucleus	3.47e-01	1.00e+00	0.419	4	158	3246
GO:0007165	signal transduction	4.45e-01	1.00e+00	0.812	1	24	618
GO:0070062	extracellular vesicular exosome	4.62e-01	1.00e+00	0.403	2	51	1641
GO:0008270	zinc ion binding	5.02e-01	1.00e+00	0.578	1	39	727
GO:0005886	plasma membrane	5.10e-01	1.00e+00	0.283	2	46	1784
GO:0044822	poly(A) RNA binding	5.36e-01	1.00e+00	0.441	1	45	799
GO:0005730	nucleolus	6.98e-01	1.00e+00	-0.166	1	74	1217

chia-Fav

reg-snw-55611

Statistics

Genes (9)

Interactions (10)

Related GO terms (123)