reg-snw-51566

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.348 4.76e-08 1.76e-02 1.44e-02
chia-screen-data-Fav-reg-snw-51566 subnetwork

Genes (8)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
KARS 3735 12-1.7592.428123TF--
MAGEH1 28986 2-2.3072.3863-Yes-
CENPA 1058 27-2.1852.393205TFYes-
[ ARMCX3 ] 51566 1-1.6182.3485TF--
PHB2 11331 17-2.2362.44911-Yes-
PHB 5245 82-2.7432.68936-YesYes
GSPT1 2935 32-2.3132.50317-YesYes
GPS1 2873 86-3.6212.68936TFYesYes

Interactions (8)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
KARS 3735 ARMCX3 51566 pd <> reg.ITFP.txt: no annot
CENPA 1058 KARS 3735 pd <> reg.ITFP.txt: no annot
KARS 3735 PHB2 11331 pd > reg.ITFP.txt: no annot
KARS 3735 PHB 5245 pd > reg.ITFP.txt: no annot
MAGEH1 28986 ARMCX3 51566 pd < reg.ITFP.txt: no annot
GSPT1 2935 KARS 3735 pd < reg.ITFP.txt: no annot
GPS1 2873 PHB 5245 pd > reg.ITFP.txt: no annot
GPS1 2873 PHB2 11331 pd > reg.ITFP.txt: no annot

Related GO terms (88)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0000939condensed chromosome inner kinetochore8.19e-041.00e+0010.253111
GO:0006430lysyl-tRNA aminoacylation8.19e-041.00e+0010.253111
GO:0004824lysine-tRNA ligase activity8.19e-041.00e+0010.253111
GO:0015966diadenosine tetraphosphate biosynthetic process1.64e-031.00e+009.253112
GO:0017101aminoacyl-tRNA synthetase multienzyme complex1.64e-031.00e+009.253112
GO:0003747translation release factor activity1.64e-031.00e+009.253122
GO:0000778condensed nuclear chromosome kinetochore2.46e-031.00e+008.668123
GO:0071459protein localization to chromosome, centromeric region2.46e-031.00e+008.668113
GO:0060762regulation of branching involved in mammary gland duct morphogenesis3.27e-031.00e+008.253114
GO:0060744mammary gland branching involved in thelarche4.09e-031.00e+007.931115
GO:2000323negative regulation of glucocorticoid receptor signaling pathway4.09e-031.00e+007.931115
GO:0033600negative regulation of mammary gland epithelial cell proliferation4.09e-031.00e+007.931115
GO:0050847progesterone receptor signaling pathway4.91e-031.00e+007.668126
GO:0000780condensed nuclear chromosome, centromeric region5.72e-031.00e+007.446117
GO:0051382kinetochore assembly5.72e-031.00e+007.446127
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway5.72e-031.00e+007.446127
GO:0010944negative regulation of transcription by competitive promoter binding6.54e-031.00e+007.253118
GO:0010388cullin deneddylation6.54e-031.00e+007.253148
GO:0071354cellular response to interleukin-67.35e-031.00e+007.083119
GO:0005095GTPase inhibitor activity8.17e-031.00e+006.9311110
GO:0060766negative regulation of androgen receptor signaling pathway8.98e-031.00e+006.7941411
GO:0006479protein methylation8.98e-031.00e+006.7941211
GO:0000132establishment of mitotic spindle orientation9.79e-031.00e+006.6681212
GO:0005743mitochondrial inner membrane1.05e-021.00e+003.63129197
GO:0060749mammary gland alveolus development1.06e-021.00e+006.5531113
GO:0016597amino acid binding1.14e-021.00e+006.4461114
GO:0016575histone deacetylation1.14e-021.00e+006.4461214
GO:0000188inactivation of MAPK activity1.22e-021.00e+006.3471115
GO:0031307integral component of mitochondrial outer membrane1.22e-021.00e+006.3471115
GO:0005739mitochondrion1.33e-021.00e+002.474332659
GO:0034080CENP-A containing nucleosome assembly1.63e-021.00e+005.9311220
GO:0071897DNA biosynthetic process1.63e-021.00e+005.9311220
GO:0030331estrogen receptor binding1.79e-021.00e+005.7941222
GO:0000049tRNA binding1.87e-021.00e+005.7301223
GO:0008180COP9 signalosome1.95e-021.00e+005.6681624
GO:0008033tRNA processing2.03e-021.00e+005.6101225
GO:0034613cellular protein localization2.11e-021.00e+005.5531126
GO:0006418tRNA aminoacylation for protein translation2.35e-021.00e+005.3951429
GO:0045892negative regulation of transcription, DNA-templated2.58e-021.00e+002.945217317
GO:0000786nucleosome2.75e-021.00e+005.1661234
GO:0007254JNK cascade2.75e-021.00e+005.1661134
GO:0000775chromosome, centromeric region3.31e-021.00e+004.8961641
GO:0006334nucleosome assembly4.10e-021.00e+004.5811451
GO:0016032viral process4.50e-021.00e+002.512230428
GO:0042826histone deacetylase binding4.66e-021.00e+004.3951558
GO:0006415translational termination5.05e-021.00e+004.2761263
GO:0030308negative regulation of cell growth5.59e-021.00e+004.1241370
GO:0016363nuclear matrix5.83e-021.00e+004.06411073
GO:0001649osteoblast differentiation5.91e-021.00e+004.0441574
GO:0015630microtubule cytoskeleton5.98e-021.00e+004.0251575
GO:0005515protein binding6.50e-021.00e+000.82961984124
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay6.68e-021.00e+003.8611584
GO:0005634nucleus8.69e-021.00e+000.91151583246
GO:0042981regulation of apoptotic process8.82e-021.00e+003.44614112
GO:0007049cell cycle9.05e-021.00e+003.40818115
GO:0003924GTPase activity9.35e-021.00e+003.35917119
GO:0000082G1/S transition of mitotic cell cycle9.80e-021.00e+003.28814125
GO:0006184GTP catabolic process1.02e-011.00e+003.23117130
GO:0005759mitochondrial matrix1.08e-011.00e+003.13417139
GO:0044212transcription regulatory region DNA binding1.11e-011.00e+003.094113143
GO:0005622intracellular1.13e-011.00e+003.07312145
GO:0005737cytoplasm1.43e-011.00e+000.89141272633
GO:0005525GTP binding1.50e-011.00e+002.631112197
GO:0005654nucleoplasm1.57e-011.00e+001.479268876
GO:0043234protein complex1.60e-011.00e+002.539113210
GO:0019899enzyme binding1.60e-011.00e+002.53917210
GO:0003682chromatin binding1.89e-011.00e+002.276115252
GO:0046982protein heterodimerization activity1.98e-011.00e+002.204111265
GO:0008285negative regulation of cell proliferation2.06e-011.00e+002.140111277
GO:0000278mitotic cell cycle2.30e-011.00e+001.959128314
GO:0045893positive regulation of transcription, DNA-templated2.70e-011.00e+001.695121377
GO:0006915apoptotic process2.91e-011.00e+001.570115411
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.18e-011.00e+001.421129456
GO:0010467gene expression3.63e-011.00e+001.190149535
GO:0005887integral component of plasma membrane3.85e-011.00e+001.08618575
GO:0070062extracellular vesicular exosome4.00e-011.00e+000.5732511641
GO:0007165signal transduction4.07e-011.00e+000.982124618
GO:0045944positive regulation of transcription from RNA polymerase II promoter4.21e-011.00e+000.922129644
GO:0005576extracellular region4.30e-011.00e+000.881115663
GO:0005829cytosol4.46e-011.00e+000.4502881787
GO:0006355regulation of transcription, DNA-templated4.56e-011.00e+000.772131715
GO:0044822poly(A) RNA binding4.95e-011.00e+000.611145799
GO:0005524ATP binding5.35e-011.00e+000.453137892
GO:0046872metal ion binding5.53e-011.00e+000.386124934
GO:0003677DNA binding5.58e-011.00e+000.366152947
GO:0006351transcription, DNA-templated6.07e-011.00e+000.1821471076
GO:0016020membrane6.52e-011.00e+000.0161561207
GO:0005886plasma membrane8.01e-011.00e+00-0.5471461784