reg-snw-2068

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.379	3.19e-08	1.40e-02	1.17e-02

chia-screen-data-Fav-reg-snw-2068 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
CSNK2B	1460	1	-1.874	2.379	15	-	-	-
[ ERCC2 ]	2068	1	-1.421	2.379	12	TF	-	-
C16orf13	84326	12	-2.090	2.492	36	-	Yes	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
DRG2	1819	15	-2.526	2.492	11	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DRG2	1819	ERCC2	2068	pd	<	reg.ITFP.txt: no annot
ERCC2	2068	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
CSNK2B	1460	ERCC2	2068	pd	<	reg.ITFP.txt: no annot
GPS1	2873	C16orf13	84326	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot

Related GO terms (114)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005956	protein kinase CK2 complex	6.14e-04	1.00e+00	10.668	1	1	1
GO:0048820	hair follicle maturation	1.23e-03	1.00e+00	9.668	1	1	2
GO:1901990	regulation of mitotic cell cycle phase transition	1.84e-03	1.00e+00	9.083	1	1	3
GO:0033683	nucleotide-excision repair, DNA incision	1.84e-03	1.00e+00	9.083	1	1	3
GO:0032289	central nervous system myelin formation	1.84e-03	1.00e+00	9.083	1	1	3
GO:0019887	protein kinase regulator activity	1.84e-03	1.00e+00	9.083	1	2	3
GO:0043139	5'-3' DNA helicase activity	1.84e-03	1.00e+00	9.083	1	1	3
GO:0061154	endothelial tube morphogenesis	2.46e-03	1.00e+00	8.668	1	1	4
GO:0035315	hair cell differentiation	2.46e-03	1.00e+00	8.668	1	1	4
GO:0033211	adiponectin-activated signaling pathway	2.46e-03	1.00e+00	8.668	1	1	4
GO:0071817	MMXD complex	2.46e-03	1.00e+00	8.668	1	2	4
GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex	3.07e-03	1.00e+00	8.347	1	2	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	3.07e-03	1.00e+00	8.347	1	1	5
GO:0040016	embryonic cleavage	3.07e-03	1.00e+00	8.347	1	1	5
GO:0032927	positive regulation of activin receptor signaling pathway	3.07e-03	1.00e+00	8.347	1	1	5
GO:0000439	core TFIIH complex	3.07e-03	1.00e+00	8.347	1	1	5
GO:0051101	regulation of DNA binding	3.07e-03	1.00e+00	8.347	1	1	5
GO:0050847	progesterone receptor signaling pathway	3.68e-03	1.00e+00	8.083	1	2	6
GO:0007165	signal transduction	4.37e-03	1.00e+00	2.982	3	24	618
GO:0005675	holo TFIIH complex	4.91e-03	1.00e+00	7.668	1	1	8
GO:0010944	negative regulation of transcription by competitive promoter binding	4.91e-03	1.00e+00	7.668	1	1	8
GO:0009650	UV protection	4.91e-03	1.00e+00	7.668	1	1	8
GO:0010388	cullin deneddylation	4.91e-03	1.00e+00	7.668	1	4	8
GO:0043249	erythrocyte maturation	5.52e-03	1.00e+00	7.499	1	1	9
GO:0060218	hematopoietic stem cell differentiation	5.52e-03	1.00e+00	7.499	1	1	9
GO:0043537	negative regulation of blood vessel endothelial cell migration	5.52e-03	1.00e+00	7.499	1	1	9
GO:0071354	cellular response to interleukin-6	5.52e-03	1.00e+00	7.499	1	1	9
GO:0005095	GTPase inhibitor activity	6.13e-03	1.00e+00	7.347	1	1	10
GO:0005737	cytoplasm	6.61e-03	1.00e+00	1.628	5	127	2633
GO:0060766	negative regulation of androgen receptor signaling pathway	6.74e-03	1.00e+00	7.209	1	4	11
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity	6.74e-03	1.00e+00	7.209	1	1	11
GO:0045859	regulation of protein kinase activity	8.57e-03	1.00e+00	6.861	1	1	14
GO:0016575	histone deacetylation	8.57e-03	1.00e+00	6.861	1	2	14
GO:0043623	cellular protein complex assembly	8.57e-03	1.00e+00	6.861	1	1	14
GO:0000188	inactivation of MAPK activity	9.18e-03	1.00e+00	6.762	1	1	15
GO:0021510	spinal cord development	1.04e-02	1.00e+00	6.581	1	1	17
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	1.04e-02	1.00e+00	6.581	1	1	17
GO:0000718	nucleotide-excision repair, DNA damage removal	1.04e-02	1.00e+00	6.581	1	1	17
GO:0031519	PcG protein complex	1.10e-02	1.00e+00	6.499	1	3	18
GO:0008285	negative regulation of cell proliferation	1.12e-02	1.00e+00	3.555	2	11	277
GO:0006362	transcription elongation from RNA polymerase I promoter	1.22e-02	1.00e+00	6.347	1	3	20
GO:0071897	DNA biosynthetic process	1.22e-02	1.00e+00	6.347	1	2	20
GO:0006363	termination of RNA polymerase I transcription	1.28e-02	1.00e+00	6.276	1	3	21
GO:0043388	positive regulation of DNA binding	1.28e-02	1.00e+00	6.276	1	2	21
GO:0030282	bone mineralization	1.28e-02	1.00e+00	6.276	1	1	21
GO:0051539	4 iron, 4 sulfur cluster binding	1.28e-02	1.00e+00	6.276	1	4	21
GO:0006468	protein phosphorylation	1.31e-02	1.00e+00	3.435	2	6	301
GO:0006361	transcription initiation from RNA polymerase I promoter	1.41e-02	1.00e+00	6.145	1	2	23
GO:0008180	COP9 signalosome	1.47e-02	1.00e+00	6.083	1	6	24
GO:0006370	7-methylguanosine mRNA capping	1.47e-02	1.00e+00	6.083	1	5	24
GO:0004003	ATP-dependent DNA helicase activity	1.53e-02	1.00e+00	6.025	1	3	25
GO:0006360	transcription from RNA polymerase I promoter	1.65e-02	1.00e+00	5.914	1	4	27
GO:0008094	DNA-dependent ATPase activity	1.77e-02	1.00e+00	5.810	1	6	29
GO:0045893	positive regulation of transcription, DNA-templated	2.01e-02	1.00e+00	3.110	2	21	377
GO:0007254	JNK cascade	2.07e-02	1.00e+00	5.581	1	1	34
GO:0050434	positive regulation of viral transcription	2.13e-02	1.00e+00	5.539	1	5	35
GO:0032508	DNA duplex unwinding	2.31e-02	1.00e+00	5.421	1	3	38
GO:0006283	transcription-coupled nucleotide-excision repair	2.43e-02	1.00e+00	5.347	1	6	40
GO:0007059	chromosome segregation	3.03e-02	1.00e+00	5.025	1	4	50
GO:0009791	post-embryonic development	3.15e-02	1.00e+00	4.968	1	2	52
GO:0006368	transcription elongation from RNA polymerase II promoter	3.15e-02	1.00e+00	4.968	1	8	52
GO:0006289	nucleotide-excision repair	3.21e-02	1.00e+00	4.941	1	6	53
GO:0035264	multicellular organism growth	3.27e-02	1.00e+00	4.914	1	2	54
GO:0042826	histone deacetylase binding	3.51e-02	1.00e+00	4.810	1	5	58
GO:0006979	response to oxidative stress	3.87e-02	1.00e+00	4.668	1	3	64
GO:0047485	protein N-terminus binding	3.93e-02	1.00e+00	4.646	1	6	65
GO:0030308	negative regulation of cell growth	4.23e-02	1.00e+00	4.539	1	3	70
GO:0001649	osteoblast differentiation	4.46e-02	1.00e+00	4.459	1	5	74
GO:0005819	spindle	4.82e-02	1.00e+00	4.347	1	6	80
GO:0016055	Wnt signaling pathway	5.23e-02	1.00e+00	4.225	1	6	87
GO:0005739	mitochondrion	5.69e-02	1.00e+00	2.304	2	32	659
GO:0007568	aging	5.82e-02	1.00e+00	4.069	1	3	97
GO:0042981	regulation of apoptotic process	6.69e-02	1.00e+00	3.861	1	4	112
GO:0008022	protein C-terminus binding	6.86e-02	1.00e+00	3.823	1	5	115
GO:0007049	cell cycle	6.86e-02	1.00e+00	3.823	1	8	115
GO:0001666	response to hypoxia	6.92e-02	1.00e+00	3.810	1	2	116
GO:0004672	protein kinase activity	7.44e-02	1.00e+00	3.703	1	5	125
GO:0019904	protein domain specific binding	7.73e-02	1.00e+00	3.646	1	4	130
GO:0044212	transcription regulatory region DNA binding	8.47e-02	1.00e+00	3.509	1	13	143
GO:0001701	in utero embryonic development	9.10e-02	1.00e+00	3.402	1	7	154
GO:0005654	nucleoplasm	9.46e-02	1.00e+00	1.894	2	68	876
GO:0006367	transcription initiation from RNA polymerase II promoter	9.50e-02	1.00e+00	3.338	1	18	161
GO:0005634	nucleus	9.92e-02	1.00e+00	1.004	4	158	3246
GO:0005102	receptor binding	1.02e-01	1.00e+00	3.225	1	3	174
GO:0046872	metal ion binding	1.06e-01	1.00e+00	1.801	2	24	934
GO:0005743	mitochondrial inner membrane	1.15e-01	1.00e+00	3.046	1	9	197
GO:0004674	protein serine/threonine kinase activity	1.15e-01	1.00e+00	3.046	1	8	197
GO:0005525	GTP binding	1.15e-01	1.00e+00	3.046	1	12	197
GO:0006281	DNA repair	1.18e-01	1.00e+00	3.003	1	24	203
GO:0008134	transcription factor binding	1.22e-01	1.00e+00	2.961	1	10	209
GO:0019899	enzyme binding	1.22e-01	1.00e+00	2.954	1	7	210
GO:0006200	ATP catabolic process	1.27e-01	1.00e+00	2.894	1	13	219
GO:0030198	extracellular matrix organization	1.28e-01	1.00e+00	2.881	1	7	221
GO:0007411	axon guidance	1.37e-01	1.00e+00	2.780	1	8	237
GO:0008283	cell proliferation	1.38e-01	1.00e+00	2.768	1	8	239
GO:0016020	membrane	1.63e-01	1.00e+00	1.431	2	56	1207
GO:0000278	mitotic cell cycle	1.78e-01	1.00e+00	2.374	1	28	314
GO:0045892	negative regulation of transcription, DNA-templated	1.80e-01	1.00e+00	2.360	1	17	317
GO:0006366	transcription from RNA polymerase II promoter	1.92e-01	1.00e+00	2.255	1	23	341
GO:0042802	identical protein binding	1.99e-01	1.00e+00	2.201	1	15	354
GO:0005515	protein binding	2.11e-01	1.00e+00	0.659	4	198	4124
GO:0006915	apoptotic process	2.27e-01	1.00e+00	1.985	1	15	411
GO:0016032	viral process	2.36e-01	1.00e+00	1.927	1	30	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.49e-01	1.00e+00	1.836	1	29	456
GO:0070062	extracellular vesicular exosome	2.67e-01	1.00e+00	0.988	2	51	1641
GO:0010467	gene expression	2.87e-01	1.00e+00	1.605	1	49	535
GO:0005887	integral component of plasma membrane	3.05e-01	1.00e+00	1.501	1	8	575
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.36e-01	1.00e+00	1.338	1	29	644
GO:0006355	regulation of transcription, DNA-templated	3.66e-01	1.00e+00	1.187	1	31	715
GO:0044281	small molecule metabolic process	4.19e-01	1.00e+00	0.947	1	35	844
GO:0005524	ATP binding	4.37e-01	1.00e+00	0.868	1	37	892
GO:0003677	DNA binding	4.58e-01	1.00e+00	0.781	1	52	947
GO:0005886	plasma membrane	7.02e-01	1.00e+00	-0.132	1	46	1784
GO:0005829	cytosol	7.03e-01	1.00e+00	-0.135	1	88	1787

chia-Fav

reg-snw-2068

Statistics

Genes (6)

Interactions (5)

Related GO terms (114)