reg-snw-137695

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.215	2.42e-07	4.28e-02	3.26e-02

chia-screen-data-Fav-reg-snw-137695 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
TDP1	55775	5	-1.669	2.428	52	-	-	-
[ TMEM68 ]	137695	6	-1.565	2.312	97	TF	-	-
SUV39H2	79723	27	-2.307	2.410	21	-	Yes	Yes
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
TRAIP	10293	13	-2.546	2.454	30	TF	Yes	-
PPA2	27068	1	-1.714	2.215	23	-	-	-
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes

Interactions (9)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PPA2	27068	TMEM68	137695	pd	<	reg.ITFP.txt: no annot
CPSF3	51692	TMEM68	137695	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	SUV39H2	79723	pd	>	reg.ITFP.txt: no annot
TDP1	55775	TMEM68	137695	pd	<	reg.ITFP.txt: no annot
TRAIP	10293	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	TDP1	55775	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
SUV39H2	79723	TMEM68	137695	pd	<	reg.ITFP.txt: no annot

Related GO terms (97)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003723	RNA binding	8.15e-04	1.00e+00	3.890	3	22	247
GO:0017005	3'-tyrosyl-DNA phosphodiesterase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0016149	translation release factor activity, codon specific	8.19e-04	1.00e+00	10.253	1	1	1
GO:0008079	translation termination factor activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0071344	diphosphate metabolic process	8.19e-04	1.00e+00	10.253	1	1	1
GO:0004427	inorganic diphosphatase activity	1.64e-03	1.00e+00	9.253	1	1	2
GO:0003747	translation release factor activity	1.64e-03	1.00e+00	9.253	1	2	2
GO:0030529	ribonucleoprotein complex	1.89e-03	1.00e+00	4.896	2	5	82
GO:0036123	histone H3-K9 dimethylation	2.46e-03	1.00e+00	8.668	1	1	3
GO:0006449	regulation of translational termination	3.27e-03	1.00e+00	8.253	1	1	4
GO:0000012	single strand break repair	3.27e-03	1.00e+00	8.253	1	1	4
GO:0006333	chromatin assembly or disassembly	3.27e-03	1.00e+00	8.253	1	1	4
GO:0036124	histone H3-K9 trimethylation	3.27e-03	1.00e+00	8.253	1	2	4
GO:0097452	GAIT complex	3.27e-03	1.00e+00	8.253	1	2	4
GO:0004521	endoribonuclease activity	4.09e-03	1.00e+00	7.931	1	1	5
GO:0006398	histone mRNA 3'-end processing	4.09e-03	1.00e+00	7.931	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	4.09e-03	1.00e+00	7.931	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.09e-03	1.00e+00	7.931	1	2	5
GO:0000398	mRNA splicing, via spliceosome	4.53e-03	1.00e+00	4.253	2	15	128
GO:0070937	CRD-mediated mRNA stability complex	4.91e-03	1.00e+00	7.668	1	2	6
GO:0042754	negative regulation of circadian rhythm	4.91e-03	1.00e+00	7.668	1	2	6
GO:0046974	histone methyltransferase activity (H3-K9 specific)	4.91e-03	1.00e+00	7.668	1	1	6
GO:0007140	male meiosis	5.72e-03	1.00e+00	7.446	1	1	7
GO:0008409	5'-3' exonuclease activity	5.72e-03	1.00e+00	7.446	1	2	7
GO:0006379	mRNA cleavage	7.35e-03	1.00e+00	7.083	1	2	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	7.35e-03	1.00e+00	7.083	1	3	9
GO:0008380	RNA splicing	7.43e-03	1.00e+00	3.887	2	21	165
GO:0010467	gene expression	7.44e-03	1.00e+00	2.775	3	49	535
GO:0008143	poly(A) binding	8.17e-03	1.00e+00	6.931	1	2	10
GO:0006479	protein methylation	8.98e-03	1.00e+00	6.794	1	2	11
GO:0004527	exonuclease activity	9.79e-03	1.00e+00	6.668	1	4	12
GO:0016746	transferase activity, transferring acyl groups	1.14e-02	1.00e+00	6.446	1	2	14
GO:0043022	ribosome binding	1.38e-02	1.00e+00	6.166	1	2	17
GO:0006378	mRNA polyadenylation	1.47e-02	1.00e+00	6.083	1	3	18
GO:0071346	cellular response to interferon-gamma	1.63e-02	1.00e+00	5.931	1	2	20
GO:0005720	nuclear heterochromatin	1.63e-02	1.00e+00	5.931	1	3	20
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	1.71e-02	1.00e+00	5.861	1	2	21
GO:0000976	transcription regulatory region sequence-specific DNA binding	2.03e-02	1.00e+00	5.610	1	3	25
GO:0005057	receptor signaling protein activity	2.11e-02	1.00e+00	5.553	1	2	26
GO:0004722	protein serine/threonine phosphatase activity	2.27e-02	1.00e+00	5.446	1	1	28
GO:0006418	tRNA aminoacylation for protein translation	2.35e-02	1.00e+00	5.395	1	4	29
GO:0090305	nucleic acid phosphodiester bond hydrolysis	2.51e-02	1.00e+00	5.299	1	6	31
GO:0017148	negative regulation of translation	2.67e-02	1.00e+00	5.209	1	5	33
GO:0031124	mRNA 3'-end processing	2.83e-02	1.00e+00	5.124	1	4	35
GO:0006369	termination of RNA polymerase II transcription	3.07e-02	1.00e+00	5.005	1	5	38
GO:0048511	rhythmic process	3.07e-02	1.00e+00	5.005	1	5	38
GO:0006396	RNA processing	3.23e-02	1.00e+00	4.931	1	4	40
GO:0000775	chromosome, centromeric region	3.31e-02	1.00e+00	4.896	1	6	41
GO:0006406	mRNA export from nucleus	3.55e-02	1.00e+00	4.794	1	7	44
GO:0006302	double-strand break repair	4.18e-02	1.00e+00	4.553	1	5	52
GO:0006338	chromatin remodeling	4.42e-02	1.00e+00	4.472	1	7	55
GO:0016311	dephosphorylation	4.42e-02	1.00e+00	4.472	1	3	55
GO:0003697	single-stranded DNA binding	4.58e-02	1.00e+00	4.421	1	4	57
GO:0000785	chromatin	4.73e-02	1.00e+00	4.371	1	6	59
GO:0071013	catalytic step 2 spliceosome	4.89e-02	1.00e+00	4.323	1	5	61
GO:0006415	translational termination	5.05e-02	1.00e+00	4.276	1	2	63
GO:0001649	osteoblast differentiation	5.91e-02	1.00e+00	4.044	1	5	74
GO:0071456	cellular response to hypoxia	6.06e-02	1.00e+00	4.005	1	2	76
GO:0005515	protein binding	6.50e-02	1.00e+00	0.829	6	198	4124
GO:0003690	double-stranded DNA binding	6.60e-02	1.00e+00	3.878	1	6	83
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.68e-02	1.00e+00	3.861	1	5	84
GO:0000287	magnesium ion binding	9.05e-02	1.00e+00	3.408	1	4	115
GO:0005759	mitochondrial matrix	1.08e-01	1.00e+00	3.134	1	7	139
GO:0016874	ligase activity	1.14e-01	1.00e+00	3.064	1	11	146
GO:0008270	zinc ion binding	1.15e-01	1.00e+00	1.748	2	39	727
GO:0016071	mRNA metabolic process	1.31e-01	1.00e+00	2.844	1	10	170
GO:0000166	nucleotide binding	1.35e-01	1.00e+00	2.794	1	13	176
GO:0044822	poly(A) RNA binding	1.35e-01	1.00e+00	1.611	2	45	799
GO:0006412	translation	1.37e-01	1.00e+00	2.778	1	12	178
GO:0004842	ubiquitin-protein transferase activity	1.38e-01	1.00e+00	2.770	1	17	179
GO:0008152	metabolic process	1.40e-01	1.00e+00	2.746	1	6	182
GO:0016070	RNA metabolic process	1.44e-01	1.00e+00	2.699	1	10	188
GO:0016567	protein ubiquitination	1.44e-01	1.00e+00	2.699	1	14	188
GO:0035556	intracellular signal transduction	1.52e-01	1.00e+00	2.617	1	5	199
GO:0030154	cell differentiation	1.55e-01	1.00e+00	2.581	1	5	204
GO:0006281	DNA repair	1.55e-01	1.00e+00	2.588	1	24	203
GO:0005654	nucleoplasm	1.57e-01	1.00e+00	1.479	2	68	876
GO:0008283	cell proliferation	1.80e-01	1.00e+00	2.353	1	8	239
GO:0003682	chromatin binding	1.89e-01	1.00e+00	2.276	1	15	252
GO:0045892	negative regulation of transcription, DNA-templated	2.32e-01	1.00e+00	1.945	1	17	317
GO:0006366	transcription from RNA polymerase II promoter	2.48e-01	1.00e+00	1.840	1	23	341
GO:0048471	perinuclear region of cytoplasm	2.49e-01	1.00e+00	1.827	1	11	344
GO:0044267	cellular protein metabolic process	2.55e-01	1.00e+00	1.794	1	14	352
GO:0005783	endoplasmic reticulum	2.73e-01	1.00e+00	1.680	1	12	381
GO:0006915	apoptotic process	2.91e-01	1.00e+00	1.570	1	15	411
GO:0016032	viral process	3.01e-01	1.00e+00	1.512	1	30	428
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.18e-01	1.00e+00	1.421	1	29	456
GO:0007165	signal transduction	4.07e-01	1.00e+00	0.982	1	24	618
GO:0046872	metal ion binding	5.53e-01	1.00e+00	0.386	1	24	934
GO:0006351	transcription, DNA-templated	6.07e-01	1.00e+00	0.182	1	47	1076
GO:0016020	membrane	6.52e-01	1.00e+00	0.016	1	56	1207
GO:0005730	nucleolus	6.55e-01	1.00e+00	0.004	1	74	1217
GO:0005737	cytoplasm	6.80e-01	1.00e+00	-0.109	2	127	2633
GO:0016021	integral component of membrane	7.43e-01	1.00e+00	-0.322	1	19	1526
GO:0070062	extracellular vesicular exosome	7.71e-01	1.00e+00	-0.427	1	51	1641
GO:0005829	cytosol	8.02e-01	1.00e+00	-0.550	1	88	1787
GO:0005634	nucleus	8.04e-01	1.00e+00	-0.411	2	158	3246

chia-Fav

reg-snw-137695

Statistics

Genes (8)

Interactions (9)

Related GO terms (97)