reg-snw-10767

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.276	1.16e-07	2.90e-02	2.26e-02

chia-screen-data-Fav-reg-snw-10767 subnetwork

Genes (18)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
PSMD2	5708	1	-4.172	2.276	3	-	Yes	Yes
EIF2S2	8894	40	-2.999	2.459	22	-	Yes	Yes
MRPS17	51373	1	-0.714	2.276	183	TF	-	-
CENPA	1058	27	-2.185	2.393	205	TF	Yes	-
HINT1	3094	1	-2.156	2.276	10	-	Yes	-
COPS4	51138	1	-3.198	2.276	15	TF	Yes	Yes
COPS3	8533	8	-1.873	2.435	79	TF	-	-
PARP2	10038	2	-1.540	2.276	23	TF	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
CCT7	10574	40	-2.335	2.459	38	-	Yes	-
GTF3C3	9330	5	-1.450	2.428	62	TF	-	-
EIF2B3	8891	8	-2.546	2.435	4	-	Yes	Yes
NOLC1	9221	15	-1.985	2.503	113	TF	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
[ HBS1L ]	10767	1	-0.590	2.276	11	-	-	-
ZNHIT3	9326	4	-2.085	2.276	6	-	Yes	-

Interactions (21)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
PARP2	10038	HBS1L	10767	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	NOLC1	9221	pd	<	reg.ITFP.txt: no annot
NOLC1	9221	HBS1L	10767	pd	>	reg.ITFP.txt: no annot
CENPA	1058	MRPS17	51373	pd	<>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
GTF3C3	9330	HBS1L	10767	pd	>	reg.ITFP.txt: no annot
COPS3	8533	MRPS17	51373	pd	<>	reg.ITFP.txt: no annot
COPS3	8533	HBS1L	10767	pd	>	reg.ITFP.txt: no annot
EIF2S2	8894	MRPS17	51373	pd	<	reg.ITFP.txt: no annot
HBS1L	10767	MRPS17	51373	pd	<	reg.ITFP.txt: no annot
CCT7	10574	MRPS17	51373	pd	<	reg.ITFP.txt: no annot
HBS1L	10767	COPS4	51138	pd	<	reg.ITFP.txt: no annot
PSMD2	5708	MRPS17	51373	pd	<	reg.ITFP.txt: no annot
GSPT1	2935	MRPS17	51373	pd	<	reg.ITFP.txt: no annot
HINT1	3094	COPS4	51138	pd	<	reg.ITFP.txt: no annot
COPS3	8533	EIF2B3	8891	pd	>	reg.ITFP.txt: no annot
EIF2S2	8894	GTF3C3	9330	pd	<	reg.ITFP.txt: no annot
NOLC1	9221	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
CENPA	1058	PARP2	10038	pd	<>	reg.ITFP.txt: no annot
PHB	5245	MRPS17	51373	pd	<	reg.ITFP.txt: no annot
ZNHIT3	9326	MRPS17	51373	pd	<	reg.ITFP.txt: no annot

Related GO terms (149)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0010388	cullin deneddylation	2.93e-07	2.86e-03	7.668	3	4	8
GO:0008180	COP9 signalosome	1.04e-05	1.01e-01	6.083	3	6	24
GO:0006412	translation	2.67e-04	1.00e+00	3.608	4	12	178
GO:0008135	translation factor activity, nucleic acid binding	3.32e-04	1.00e+00	6.177	2	4	15
GO:0002128	tRNA nucleoside ribose methylation	1.84e-03	1.00e+00	9.083	1	1	1
GO:0008175	tRNA methyltransferase activity	1.84e-03	1.00e+00	9.083	1	1	1
GO:0000939	condensed chromosome inner kinetochore	1.84e-03	1.00e+00	9.083	1	1	1
GO:0009154	purine ribonucleotide catabolic process	1.84e-03	1.00e+00	9.083	1	1	1
GO:0003743	translation initiation factor activity	2.06e-03	1.00e+00	4.874	2	8	37
GO:0051716	cellular response to stimulus	3.68e-03	1.00e+00	8.083	1	1	2
GO:0003747	translation release factor activity	3.68e-03	1.00e+00	8.083	1	2	2
GO:0002176	male germ cell proliferation	3.68e-03	1.00e+00	8.083	1	1	2
GO:0005525	GTP binding	5.28e-03	1.00e+00	3.046	3	12	197
GO:0005850	eukaryotic translation initiation factor 2 complex	5.52e-03	1.00e+00	7.499	1	2	3
GO:0000778	condensed nuclear chromosome kinetochore	5.52e-03	1.00e+00	7.499	1	2	3
GO:0000338	protein deneddylation	5.52e-03	1.00e+00	7.499	1	1	3
GO:0071459	protein localization to chromosome, centromeric region	5.52e-03	1.00e+00	7.499	1	1	3
GO:0032057	negative regulation of translational initiation in response to stress	7.35e-03	1.00e+00	7.083	1	1	4
GO:0007000	nucleolus organization	7.35e-03	1.00e+00	7.083	1	1	4
GO:0005851	eukaryotic translation initiation factor 2B complex	7.35e-03	1.00e+00	7.083	1	2	4
GO:0016779	nucleotidyltransferase activity	7.35e-03	1.00e+00	7.083	1	1	4
GO:0042797	tRNA transcription from RNA polymerase III promoter	9.18e-03	1.00e+00	6.762	1	3	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	9.18e-03	1.00e+00	6.762	1	1	5
GO:0000127	transcription factor TFIIIC complex	9.18e-03	1.00e+00	6.762	1	3	5
GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter	9.18e-03	1.00e+00	6.762	1	3	5
GO:0005515	protein binding	9.83e-03	1.00e+00	0.774	13	198	4124
GO:0050847	progesterone receptor signaling pathway	1.10e-02	1.00e+00	6.499	1	2	6
GO:0002181	cytoplasmic translation	1.10e-02	1.00e+00	6.499	1	1	6
GO:0002199	zona pellucida receptor complex	1.28e-02	1.00e+00	6.276	1	4	7
GO:0000780	condensed nuclear chromosome, centromeric region	1.28e-02	1.00e+00	6.276	1	1	7
GO:0005832	chaperonin-containing T-complex	1.28e-02	1.00e+00	6.276	1	4	7
GO:0051382	kinetochore assembly	1.28e-02	1.00e+00	6.276	1	2	7
GO:0006413	translational initiation	1.40e-02	1.00e+00	3.454	2	6	99
GO:0010944	negative regulation of transcription by competitive promoter binding	1.47e-02	1.00e+00	6.083	1	1	8
GO:0010467	gene expression	1.47e-02	1.00e+00	2.020	4	49	535
GO:0071354	cellular response to interleukin-6	1.65e-02	1.00e+00	5.914	1	1	9
GO:0042981	regulation of apoptotic process	1.77e-02	1.00e+00	3.276	2	4	112
GO:0005654	nucleoplasm	1.83e-02	1.00e+00	1.631	5	68	876
GO:0006471	protein ADP-ribosylation	1.83e-02	1.00e+00	5.762	1	1	10
GO:0005095	GTPase inhibitor activity	1.83e-02	1.00e+00	5.762	1	1	10
GO:0009416	response to light stimulus	1.83e-02	1.00e+00	5.762	1	1	10
GO:0005838	proteasome regulatory particle	1.83e-02	1.00e+00	5.762	1	1	10
GO:0007049	cell cycle	1.86e-02	1.00e+00	3.238	2	8	115
GO:0003924	GTPase activity	1.98e-02	1.00e+00	3.189	2	7	119
GO:0060766	negative regulation of androgen receptor signaling pathway	2.01e-02	1.00e+00	5.624	1	4	11
GO:0006479	protein methylation	2.01e-02	1.00e+00	5.624	1	2	11
GO:0030234	enzyme regulator activity	2.01e-02	1.00e+00	5.624	1	1	11
GO:0000082	G1/S transition of mitotic cell cycle	2.18e-02	1.00e+00	3.118	2	4	125
GO:0000132	establishment of mitotic spindle orientation	2.19e-02	1.00e+00	5.499	1	2	12
GO:0003746	translation elongation factor activity	2.19e-02	1.00e+00	5.499	1	2	12
GO:0006184	GTP catabolic process	2.34e-02	1.00e+00	3.061	2	7	130
GO:0003950	NAD+ ADP-ribosyltransferase activity	2.37e-02	1.00e+00	5.383	1	1	13
GO:0007165	signal transduction	2.39e-02	1.00e+00	1.812	4	24	618
GO:0044267	cellular protein metabolic process	2.53e-02	1.00e+00	2.209	3	14	352
GO:0042176	regulation of protein catabolic process	2.55e-02	1.00e+00	5.276	1	1	14
GO:0019843	rRNA binding	2.55e-02	1.00e+00	5.276	1	1	14
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	2.55e-02	1.00e+00	5.276	1	1	14
GO:0022624	proteasome accessory complex	2.55e-02	1.00e+00	5.276	1	1	14
GO:0016575	histone deacetylation	2.55e-02	1.00e+00	5.276	1	2	14
GO:0000188	inactivation of MAPK activity	2.73e-02	1.00e+00	5.177	1	1	15
GO:0014003	oligodendrocyte development	2.73e-02	1.00e+00	5.177	1	1	15
GO:0007339	binding of sperm to zona pellucida	2.73e-02	1.00e+00	5.177	1	4	15
GO:0005622	intracellular	2.87e-02	1.00e+00	2.904	2	2	145
GO:0005763	mitochondrial small ribosomal subunit	2.91e-02	1.00e+00	5.083	1	1	16
GO:0001701	in utero embryonic development	3.20e-02	1.00e+00	2.817	2	7	154
GO:0034080	CENP-A containing nucleosome assembly	3.63e-02	1.00e+00	4.762	1	2	20
GO:0046966	thyroid hormone receptor binding	3.63e-02	1.00e+00	4.762	1	3	20
GO:0071897	DNA biosynthetic process	3.63e-02	1.00e+00	4.762	1	2	20
GO:0051084	'de novo' posttranslational protein folding	3.98e-02	1.00e+00	4.624	1	4	22
GO:0000118	histone deacetylase complex	4.16e-02	1.00e+00	4.560	1	3	23
GO:0006383	transcription from RNA polymerase III promoter	5.22e-02	1.00e+00	4.225	1	6	29
GO:0097191	extrinsic apoptotic signaling pathway	5.39e-02	1.00e+00	4.177	1	1	30
GO:0009408	response to heat	5.57e-02	1.00e+00	4.129	1	1	31
GO:0005080	protein kinase C binding	5.57e-02	1.00e+00	4.129	1	2	31
GO:0015030	Cajal body	5.74e-02	1.00e+00	4.083	1	3	32
GO:0006284	base-excision repair	5.74e-02	1.00e+00	4.083	1	3	32
GO:0000786	nucleosome	6.09e-02	1.00e+00	3.996	1	2	34
GO:0007254	JNK cascade	6.09e-02	1.00e+00	3.996	1	1	34
GO:0044297	cell body	6.26e-02	1.00e+00	3.954	1	5	35
GO:0043434	response to peptide hormone	6.44e-02	1.00e+00	3.914	1	1	36
GO:0070062	extracellular vesicular exosome	6.73e-02	1.00e+00	0.988	6	51	1641
GO:0008021	synaptic vesicle	7.13e-02	1.00e+00	3.762	1	2	40
GO:0016787	hydrolase activity	7.13e-02	1.00e+00	3.762	1	3	40
GO:0006521	regulation of cellular amino acid metabolic process	7.30e-02	1.00e+00	3.726	1	2	41
GO:0000775	chromosome, centromeric region	7.30e-02	1.00e+00	3.726	1	6	41
GO:0005085	guanyl-nucleotide exchange factor activity	7.64e-02	1.00e+00	3.657	1	2	43
GO:0009749	response to glucose	7.98e-02	1.00e+00	3.592	1	1	45
GO:0000502	proteasome complex	8.33e-02	1.00e+00	3.529	1	3	47
GO:0005737	cytoplasm	8.39e-02	1.00e+00	0.721	8	127	2633
GO:0006334	nucleosome assembly	9.00e-02	1.00e+00	3.411	1	4	51
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.17e-02	1.00e+00	3.383	1	3	52
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	9.34e-02	1.00e+00	3.356	1	3	53
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	9.84e-02	1.00e+00	3.276	1	5	56
GO:0008584	male gonad development	1.00e-01	1.00e+00	3.251	1	1	57
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	1.00e-01	1.00e+00	3.251	1	2	57
GO:0042826	histone deacetylase binding	1.02e-01	1.00e+00	3.225	1	5	58
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	1.05e-01	1.00e+00	3.177	1	5	60
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	1.07e-01	1.00e+00	3.153	1	2	61
GO:0006415	translational termination	1.10e-01	1.00e+00	3.106	1	2	63
GO:0000278	mitotic cell cycle	1.13e-01	1.00e+00	1.789	2	28	314
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	1.13e-01	1.00e+00	3.061	1	7	65
GO:0006364	rRNA processing	1.17e-01	1.00e+00	3.017	1	2	67
GO:0006414	translational elongation	1.20e-01	1.00e+00	2.975	1	2	69
GO:0030308	negative regulation of cell growth	1.22e-01	1.00e+00	2.954	1	3	70
GO:0051082	unfolded protein binding	1.22e-01	1.00e+00	2.954	1	5	70
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.22e-01	1.00e+00	2.954	1	2	70
GO:0001649	osteoblast differentiation	1.28e-01	1.00e+00	2.874	1	5	74
GO:0006355	regulation of transcription, DNA-templated	1.41e-01	1.00e+00	1.187	3	31	715
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	1.44e-01	1.00e+00	2.691	1	5	84
GO:0000209	protein polyubiquitination	1.57e-01	1.00e+00	2.560	1	6	92
GO:0006457	protein folding	1.65e-01	1.00e+00	2.484	1	5	97
GO:0034641	cellular nitrogen compound metabolic process	1.77e-01	1.00e+00	2.369	1	5	105
GO:0044822	poly(A) RNA binding	1.78e-01	1.00e+00	1.026	3	45	799
GO:0003735	structural constituent of ribosome	1.83e-01	1.00e+00	2.315	1	2	109
GO:0016032	viral process	1.85e-01	1.00e+00	1.342	2	30	428
GO:0043547	positive regulation of GTPase activity	1.88e-01	1.00e+00	2.276	1	2	112
GO:0005829	cytosol	2.22e-01	1.00e+00	0.602	5	88	1787
GO:0044212	transcription regulatory region DNA binding	2.33e-01	1.00e+00	1.924	1	13	143
GO:0003677	DNA binding	2.51e-01	1.00e+00	0.781	3	52	947
GO:0005874	microtubule	2.62e-01	1.00e+00	1.735	1	10	163
GO:0007067	mitotic nuclear division	2.64e-01	1.00e+00	1.717	1	9	165
GO:0016071	mRNA metabolic process	2.71e-01	1.00e+00	1.674	1	10	170
GO:0000166	nucleotide binding	2.79e-01	1.00e+00	1.624	1	13	176
GO:0016070	RNA metabolic process	2.95e-01	1.00e+00	1.529	1	10	188
GO:0005856	cytoskeleton	2.98e-01	1.00e+00	1.514	1	8	190
GO:0005743	mitochondrial inner membrane	3.07e-01	1.00e+00	1.461	1	9	197
GO:0006281	DNA repair	3.15e-01	1.00e+00	1.418	1	24	203
GO:0019899	enzyme binding	3.24e-01	1.00e+00	1.369	1	7	210
GO:0030054	cell junction	3.34e-01	1.00e+00	1.315	1	5	218
GO:0005739	mitochondrion	3.45e-01	1.00e+00	0.719	2	32	659
GO:0003723	RNA binding	3.70e-01	1.00e+00	1.135	1	22	247
GO:0003682	chromatin binding	3.76e-01	1.00e+00	1.106	1	15	252
GO:0016020	membrane	3.88e-01	1.00e+00	0.431	3	56	1207
GO:0046982	protein heterodimerization activity	3.91e-01	1.00e+00	1.034	1	11	265
GO:0005730	nucleolus	3.93e-01	1.00e+00	0.419	3	74	1217
GO:0008285	negative regulation of cell proliferation	4.05e-01	1.00e+00	0.970	1	11	277
GO:0045892	negative regulation of transcription, DNA-templated	4.48e-01	1.00e+00	0.775	1	17	317
GO:0043066	negative regulation of apoptotic process	4.53e-01	1.00e+00	0.753	1	8	322
GO:0042802	identical protein binding	4.86e-01	1.00e+00	0.616	1	15	354
GO:0005524	ATP binding	4.99e-01	1.00e+00	0.283	2	37	892
GO:0045893	positive regulation of transcription, DNA-templated	5.08e-01	1.00e+00	0.525	1	21	377
GO:0046872	metal ion binding	5.25e-01	1.00e+00	0.216	2	24	934
GO:0006915	apoptotic process	5.39e-01	1.00e+00	0.400	1	15	411
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	5.78e-01	1.00e+00	0.251	1	29	456
GO:0005634	nucleus	5.85e-01	1.00e+00	0.004	6	158	3246
GO:0006351	transcription, DNA-templated	6.05e-01	1.00e+00	0.012	2	47	1076
GO:0005887	integral component of plasma membrane	6.65e-01	1.00e+00	-0.084	1	8	575
GO:0044281	small molecule metabolic process	8.04e-01	1.00e+00	-0.638	1	35	844
GO:0005886	plasma membrane	9.74e-01	1.00e+00	-1.717	1	46	1784

chia-Fav

reg-snw-10767

Statistics

Genes (18)

Interactions (21)

Related GO terms (149)