int-snw-9706

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.197	1.12e-19	3.12e-06	9.46e-05

chia-screen-data-Fav-int-snw-9706 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
YAP1	10413	94	-4.256	3.538	53	Yes	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
SYNCRIP	10492	9	-2.401	3.197	103	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
H1FX	8971	7	-2.421	3.504	35	Yes	Yes
[ ULK2 ]	9706	9	-2.292	3.197	312	Yes	Yes

Interactions (8)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HNRNPU	3192	SYNCRIP	10492	pp	--	int.Mint: MI:0915(physical association)
SRSF3	6428	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
H1FX	8971	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
ULK2	9706	SYNCRIP	10492	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse

Related GO terms (84)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0070934	CRD-mediated mRNA stabilization	2.02e-06	2.91e-02	9.687	2	2	5
GO:0070937	CRD-mediated mRNA stability complex	3.03e-06	4.36e-02	9.424	2	3	6
GO:0044822	poly(A) RNA binding	3.86e-05	5.57e-01	3.286	5	50	1056
GO:0005654	nucleoplasm	4.35e-05	6.28e-01	3.251	5	64	1082
GO:0000398	mRNA splicing, via spliceosome	4.89e-05	7.05e-01	5.236	3	15	164
GO:0008380	RNA splicing	1.30e-04	1.00e+00	4.761	3	22	228
GO:0006396	RNA processing	3.41e-04	1.00e+00	6.126	2	5	59
GO:0003723	RNA binding	4.31e-04	1.00e+00	4.176	3	18	342
GO:0060795	cell fate commitment involved in formation of primary germ layer	4.85e-04	1.00e+00	11.009	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	4.85e-04	1.00e+00	11.009	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	4.85e-04	1.00e+00	11.009	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	4.85e-04	1.00e+00	11.009	1	1	1
GO:0071013	catalytic step 2 spliceosome	5.96e-04	1.00e+00	5.723	2	7	78
GO:0001649	osteoblast differentiation	8.28e-04	1.00e+00	5.485	2	5	92
GO:0009786	regulation of asymmetric cell division	9.70e-04	1.00e+00	10.009	1	1	2
GO:0060242	contact inhibition	9.70e-04	1.00e+00	10.009	1	1	2
GO:0030529	ribonucleoprotein complex	1.22e-03	1.00e+00	5.201	2	5	112
GO:0060913	cardiac cell fate determination	1.46e-03	1.00e+00	9.424	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.46e-03	1.00e+00	9.424	1	1	3
GO:0097452	GAIT complex	1.94e-03	1.00e+00	9.009	1	1	4
GO:0034273	ATG1/UKL1 signaling complex	1.94e-03	1.00e+00	9.009	1	1	4
GO:0001714	endodermal cell fate specification	2.42e-03	1.00e+00	8.687	1	1	5
GO:0048671	negative regulation of collateral sprouting	2.42e-03	1.00e+00	8.687	1	1	5
GO:0044212	transcription regulatory region DNA binding	2.73e-03	1.00e+00	4.616	2	17	168
GO:0071204	histone pre-mRNA 3'end processing complex	2.91e-03	1.00e+00	8.424	1	1	6
GO:0010467	gene expression	3.02e-03	1.00e+00	3.208	3	45	669
GO:0035413	positive regulation of catenin import into nucleus	4.84e-03	1.00e+00	7.687	1	2	10
GO:0060391	positive regulation of SMAD protein import into nucleus	5.33e-03	1.00e+00	7.549	1	4	11
GO:0034045	pre-autophagosomal structure membrane	5.81e-03	1.00e+00	7.424	1	2	12
GO:0035198	miRNA binding	5.81e-03	1.00e+00	7.424	1	1	12
GO:0008143	poly(A) binding	5.81e-03	1.00e+00	7.424	1	2	12
GO:0071480	cellular response to gamma radiation	6.29e-03	1.00e+00	7.308	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	6.29e-03	1.00e+00	7.308	1	2	13
GO:0000166	nucleotide binding	6.36e-03	1.00e+00	3.992	2	13	259
GO:0001824	blastocyst development	7.26e-03	1.00e+00	7.102	1	2	15
GO:0043274	phospholipase binding	7.74e-03	1.00e+00	7.009	1	1	16
GO:0048675	axon extension	1.01e-02	1.00e+00	6.616	1	2	21
GO:0036464	cytoplasmic ribonucleoprotein granule	1.06e-02	1.00e+00	6.549	1	2	22
GO:0071346	cellular response to interferon-gamma	1.11e-02	1.00e+00	6.485	1	1	23
GO:0010506	regulation of autophagy	1.11e-02	1.00e+00	6.485	1	2	23
GO:0035329	hippo signaling	1.26e-02	1.00e+00	6.308	1	5	26
GO:0000045	autophagic vacuole assembly	1.26e-02	1.00e+00	6.308	1	2	26
GO:0042594	response to starvation	1.50e-02	1.00e+00	6.055	1	4	31
GO:1903507	negative regulation of nucleic acid-templated transcription	1.54e-02	1.00e+00	6.009	1	2	32
GO:0006366	transcription from RNA polymerase II promoter	1.60e-02	1.00e+00	3.298	2	30	419
GO:0003677	DNA binding	1.62e-02	1.00e+00	2.343	3	49	1218
GO:0035019	somatic stem cell maintenance	1.93e-02	1.00e+00	5.687	1	6	40
GO:0017148	negative regulation of translation	1.93e-02	1.00e+00	5.687	1	2	40
GO:0031124	mRNA 3'-end processing	2.02e-02	1.00e+00	5.616	1	2	42
GO:0006369	termination of RNA polymerase II transcription	2.16e-02	1.00e+00	5.517	1	2	45
GO:0005515	protein binding	2.38e-02	1.00e+00	1.037	6	198	6024
GO:0009611	response to wounding	2.50e-02	1.00e+00	5.308	1	5	52
GO:0000786	nucleosome	2.83e-02	1.00e+00	5.126	1	2	59
GO:0006406	mRNA export from nucleus	2.92e-02	1.00e+00	5.078	1	4	61
GO:0010468	regulation of gene expression	3.25e-02	1.00e+00	4.921	1	2	68
GO:0006334	nucleosome assembly	3.44e-02	1.00e+00	4.839	1	3	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	3.54e-02	1.00e+00	4.799	1	4	74
GO:0005634	nucleus	3.60e-02	1.00e+00	1.176	5	159	4559
GO:0009653	anatomical structure morphogenesis	3.96e-02	1.00e+00	4.634	1	2	83
GO:0030659	cytoplasmic vesicle membrane	4.80e-02	1.00e+00	4.351	1	2	101
GO:0006974	cellular response to DNA damage stimulus	7.10e-02	1.00e+00	3.770	1	7	151
GO:0046777	protein autophosphorylation	7.42e-02	1.00e+00	3.705	1	4	158
GO:0006355	regulation of transcription, DNA-templated	7.95e-02	1.00e+00	2.047	2	43	997
GO:0016607	nuclear speck	8.06e-02	1.00e+00	3.582	1	12	172
GO:0005667	transcription factor complex	8.19e-02	1.00e+00	3.558	1	17	175
GO:0031625	ubiquitin protein ligase binding	8.33e-02	1.00e+00	3.533	1	5	178
GO:0003714	transcription corepressor activity	8.33e-02	1.00e+00	3.533	1	11	178
GO:0006367	transcription initiation from RNA polymerase II promoter	8.60e-02	1.00e+00	3.485	1	22	184
GO:0005829	cytosol	1.05e-01	1.00e+00	1.308	3	86	2496
GO:0003713	transcription coactivator activity	1.10e-01	1.00e+00	3.120	1	24	237
GO:0008134	transcription factor binding	1.12e-01	1.00e+00	3.090	1	18	242
GO:0005524	ATP binding	1.25e-01	1.00e+00	1.667	2	31	1298
GO:0004674	protein serine/threonine kinase activity	1.40e-01	1.00e+00	2.742	1	6	308
GO:0008283	cell proliferation	1.49e-01	1.00e+00	2.651	1	14	328
GO:0043565	sequence-specific DNA binding	1.56e-01	1.00e+00	2.574	1	11	346
GO:0009986	cell surface	1.80e-01	1.00e+00	2.358	1	9	402
GO:0016020	membrane	1.92e-01	1.00e+00	1.294	2	46	1681
GO:0016032	viral process	2.32e-01	1.00e+00	1.948	1	26	534
GO:0005783	endoplasmic reticulum	2.41e-01	1.00e+00	1.890	1	13	556
GO:0005737	cytoplasm	2.67e-01	1.00e+00	0.714	3	124	3767
GO:0003700	sequence-specific DNA binding transcription factor activity	2.94e-01	1.00e+00	1.560	1	39	699
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.26e-01	1.00e+00	1.385	1	41	789
GO:0007165	signal transduction	3.65e-01	1.00e+00	1.184	1	13	907
GO:0005730	nucleolus	5.71e-01	1.00e+00	0.328	1	66	1641

chia-Fav

int-snw-9706

Statistics

Genes (7)

Interactions (8)

Related GO terms (84)