int-snw-1996

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.149	4.35e-19	6.62e-06	1.62e-04

chia-screen-data-Fav-int-snw-1996 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
YAP1	10413	94	-4.256	3.538	53	Yes	-
NXF1	10482	10	-2.426	3.538	65	Yes	Yes
NCBP1	4686	6	-2.510	3.149	40	Yes	Yes
SRSF3	6428	73	-2.992	3.538	54	Yes	-
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
[ ELAVL4 ]	1996	1	-1.841	3.149	8	-	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ELAVL4	1996	NXF1	10482	pp	--	int.I2D: BioGrid
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
NCBP1	4686	NXF1	10482	pp	--	int.Mint: MI:0914(association)
SRSF3	6428	NXF1	10482	pp	--	int.I2D: MINT, HPRD; int.Mint: MI:0407(direct interaction), MI:0915(physical association)
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
HNRNPU	3192	NXF1	10482	pp	--	int.Intact: MI:0914(association)

Related GO terms (93)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	1.15e-06	1.66e-02	3.514	6	64	1082
GO:0006406	mRNA export from nucleus	2.49e-06	3.59e-02	6.663	3	4	61
GO:0010467	gene expression	4.11e-06	5.93e-02	3.945	5	45	669
GO:0003723	RNA binding	1.03e-05	1.48e-01	4.591	4	18	342
GO:0044822	poly(A) RNA binding	3.86e-05	5.57e-01	3.286	5	50	1056
GO:0000398	mRNA splicing, via spliceosome	4.89e-05	7.05e-01	5.236	3	15	164
GO:0008380	RNA splicing	1.30e-04	1.00e+00	4.761	3	22	228
GO:0031124	mRNA 3'-end processing	1.72e-04	1.00e+00	6.616	2	2	42
GO:0000166	nucleotide binding	1.90e-04	1.00e+00	4.577	3	13	259
GO:0006369	termination of RNA polymerase II transcription	1.98e-04	1.00e+00	6.517	2	2	45
GO:0006396	RNA processing	3.41e-04	1.00e+00	6.126	2	5	59
GO:0060795	cell fate commitment involved in formation of primary germ layer	4.85e-04	1.00e+00	11.009	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	4.85e-04	1.00e+00	11.009	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	4.85e-04	1.00e+00	11.009	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	4.85e-04	1.00e+00	11.009	1	1	1
GO:0006366	transcription from RNA polymerase II promoter	7.81e-04	1.00e+00	3.883	3	30	419
GO:0005846	nuclear cap binding complex	9.70e-04	1.00e+00	10.009	1	1	2
GO:0009786	regulation of asymmetric cell division	9.70e-04	1.00e+00	10.009	1	1	2
GO:0060242	contact inhibition	9.70e-04	1.00e+00	10.009	1	1	2
GO:0030529	ribonucleoprotein complex	1.22e-03	1.00e+00	5.201	2	5	112
GO:0060913	cardiac cell fate determination	1.46e-03	1.00e+00	9.424	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.46e-03	1.00e+00	9.424	1	1	3
GO:0001714	endodermal cell fate specification	2.42e-03	1.00e+00	8.687	1	1	5
GO:0045292	mRNA cis splicing, via spliceosome	2.42e-03	1.00e+00	8.687	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	2.42e-03	1.00e+00	8.687	1	2	5
GO:0031442	positive regulation of mRNA 3'-end processing	2.42e-03	1.00e+00	8.687	1	1	5
GO:0044212	transcription regulatory region DNA binding	2.73e-03	1.00e+00	4.616	2	17	168
GO:0016607	nuclear speck	2.85e-03	1.00e+00	4.582	2	12	172
GO:0070937	CRD-mediated mRNA stability complex	2.91e-03	1.00e+00	8.424	1	3	6
GO:0000339	RNA cap binding	3.88e-03	1.00e+00	8.009	1	1	8
GO:0016973	poly(A)+ mRNA export from nucleus	3.88e-03	1.00e+00	8.009	1	1	8
GO:0042405	nuclear inclusion body	4.36e-03	1.00e+00	7.839	1	2	9
GO:0006379	mRNA cleavage	4.36e-03	1.00e+00	7.839	1	1	9
GO:0035413	positive regulation of catenin import into nucleus	4.84e-03	1.00e+00	7.687	1	2	10
GO:0005845	mRNA cap binding complex	5.33e-03	1.00e+00	7.549	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	5.33e-03	1.00e+00	7.549	1	4	11
GO:0008334	histone mRNA metabolic process	5.81e-03	1.00e+00	7.424	1	1	12
GO:0035198	miRNA binding	5.81e-03	1.00e+00	7.424	1	1	12
GO:0071480	cellular response to gamma radiation	6.29e-03	1.00e+00	7.308	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	6.29e-03	1.00e+00	7.308	1	2	13
GO:0000346	transcription export complex	6.29e-03	1.00e+00	7.308	1	1	13
GO:0017091	AU-rich element binding	6.78e-03	1.00e+00	7.201	1	2	14
GO:0005487	nucleocytoplasmic transporter activity	6.78e-03	1.00e+00	7.201	1	3	14
GO:0001824	blastocyst development	7.26e-03	1.00e+00	7.102	1	2	15
GO:0043274	phospholipase binding	7.74e-03	1.00e+00	7.009	1	1	16
GO:0036464	cytoplasmic ribonucleoprotein granule	1.06e-02	1.00e+00	6.549	1	2	22
GO:0034660	ncRNA metabolic process	1.11e-02	1.00e+00	6.485	1	1	23
GO:0031047	gene silencing by RNA	1.21e-02	1.00e+00	6.365	1	2	25
GO:0035329	hippo signaling	1.26e-02	1.00e+00	6.308	1	5	26
GO:0003730	mRNA 3'-UTR binding	1.26e-02	1.00e+00	6.308	1	2	26
GO:0000387	spliceosomal snRNP assembly	1.30e-02	1.00e+00	6.254	1	2	27
GO:0006370	7-methylguanosine mRNA capping	1.45e-02	1.00e+00	6.102	1	5	30
GO:1903507	negative regulation of nucleic acid-templated transcription	1.54e-02	1.00e+00	6.009	1	2	32
GO:0006446	regulation of translational initiation	1.73e-02	1.00e+00	5.839	1	4	36
GO:0035019	somatic stem cell maintenance	1.93e-02	1.00e+00	5.687	1	6	40
GO:0005829	cytosol	2.01e-02	1.00e+00	1.723	4	86	2496
GO:0050434	positive regulation of viral transcription	2.12e-02	1.00e+00	5.549	1	5	44
GO:0005515	protein binding	2.38e-02	1.00e+00	1.037	6	198	6024
GO:0009611	response to wounding	2.50e-02	1.00e+00	5.308	1	5	52
GO:0016032	viral process	2.54e-02	1.00e+00	2.948	2	26	534
GO:0005643	nuclear pore	2.73e-02	1.00e+00	5.176	1	11	57
GO:0006368	transcription elongation from RNA polymerase II promoter	3.21e-02	1.00e+00	4.943	1	6	67
GO:0010468	regulation of gene expression	3.25e-02	1.00e+00	4.921	1	2	68
GO:0003729	mRNA binding	3.44e-02	1.00e+00	4.839	1	4	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	3.54e-02	1.00e+00	4.799	1	4	74
GO:0071013	catalytic step 2 spliceosome	3.73e-02	1.00e+00	4.723	1	7	78
GO:0009653	anatomical structure morphogenesis	3.96e-02	1.00e+00	4.634	1	2	83
GO:0001649	osteoblast differentiation	4.38e-02	1.00e+00	4.485	1	5	92
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	5.40e-02	1.00e+00	4.176	1	4	114
GO:0006974	cellular response to DNA damage stimulus	7.10e-02	1.00e+00	3.770	1	7	151
GO:0006397	mRNA processing	7.51e-02	1.00e+00	3.687	1	10	160
GO:0006355	regulation of transcription, DNA-templated	7.95e-02	1.00e+00	2.047	2	43	997
GO:0005737	cytoplasm	8.13e-02	1.00e+00	1.130	4	124	3767
GO:0005667	transcription factor complex	8.19e-02	1.00e+00	3.558	1	17	175
GO:0031625	ubiquitin protein ligase binding	8.33e-02	1.00e+00	3.533	1	5	178
GO:0003714	transcription corepressor activity	8.33e-02	1.00e+00	3.533	1	11	178
GO:0006367	transcription initiation from RNA polymerase II promoter	8.60e-02	1.00e+00	3.485	1	22	184
GO:0016071	mRNA metabolic process	1.03e-01	1.00e+00	3.208	1	8	223
GO:0003713	transcription coactivator activity	1.10e-01	1.00e+00	3.120	1	24	237
GO:0008134	transcription factor binding	1.12e-01	1.00e+00	3.090	1	18	242
GO:0003677	DNA binding	1.13e-01	1.00e+00	1.758	2	49	1218
GO:0016070	RNA metabolic process	1.14e-01	1.00e+00	3.060	1	8	247
GO:0005634	nucleus	1.48e-01	1.00e+00	0.854	4	159	4559
GO:0008283	cell proliferation	1.49e-01	1.00e+00	2.651	1	14	328
GO:0043565	sequence-specific DNA binding	1.56e-01	1.00e+00	2.574	1	11	346
GO:0009986	cell surface	1.80e-01	1.00e+00	2.358	1	9	402
GO:0003700	sequence-specific DNA binding transcription factor activity	2.94e-01	1.00e+00	1.560	1	39	699
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.26e-01	1.00e+00	1.385	1	41	789
GO:0005739	mitochondrion	3.95e-01	1.00e+00	1.046	1	23	998
GO:0005524	ATP binding	4.83e-01	1.00e+00	0.667	1	31	1298
GO:0005730	nucleolus	5.71e-01	1.00e+00	0.328	1	66	1641
GO:0016020	membrane	5.80e-01	1.00e+00	0.294	1	46	1681
GO:0005886	plasma membrane	7.49e-01	1.00e+00	-0.326	1	49	2582

chia-Fav

int-snw-1996

Statistics

Genes (7)

Interactions (7)

Related GO terms (93)