int-snw-1471

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.933	1.40e-16	1.42e-04	1.42e-03

chia-screen-data-Fav-int-snw-1471 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
SYNCRIP	10492	9	-2.401	3.197	103	Yes	Yes
[ CST3 ]	1471	1	-1.768	2.933	12	-	-
YAP1	10413	94	-4.256	3.538	53	Yes	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
CSTB	1476	2	-2.252	3.110	34	Yes	-
ULK2	9706	9	-2.292	3.197	312	Yes	Yes
H1FX	8971	7	-2.421	3.504	35	Yes	Yes

Interactions (10)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HNRNPU	3192	SYNCRIP	10492	pp	--	int.Mint: MI:0915(physical association)
SRSF3	6428	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
CST3	1471	CSTB	1476	pp	--	int.I2D: BioGrid
HNRNPU	3192	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
CSTB	1476	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
H1FX	8971	ULK2	9706	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
ULK2	9706	SYNCRIP	10492	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW

Related GO terms (103)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0070934	CRD-mediated mRNA stabilization	3.46e-06	4.99e-02	9.324	2	2	5
GO:0070937	CRD-mediated mRNA stability complex	5.19e-06	7.48e-02	9.061	2	3	6
GO:0010466	negative regulation of peptidase activity	9.67e-06	1.40e-01	8.646	2	2	8
GO:0044822	poly(A) RNA binding	1.05e-05	1.52e-01	3.187	6	50	1056
GO:0045861	negative regulation of proteolysis	5.27e-05	7.60e-01	7.476	2	4	18
GO:0004869	cysteine-type endopeptidase inhibitor activity	8.70e-05	1.00e+00	7.123	2	2	23
GO:0000398	mRNA splicing, via spliceosome	1.15e-04	1.00e+00	4.874	3	15	164
GO:0004866	endopeptidase inhibitor activity	1.39e-04	1.00e+00	6.788	2	3	29
GO:0005654	nucleoplasm	2.30e-04	1.00e+00	2.889	5	64	1082
GO:0008380	RNA splicing	3.05e-04	1.00e+00	4.398	3	22	228
GO:0006396	RNA processing	5.81e-04	1.00e+00	5.764	2	5	59
GO:0060311	negative regulation of elastin catabolic process	6.24e-04	1.00e+00	10.646	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	6.24e-04	1.00e+00	10.646	1	1	1
GO:0060313	negative regulation of blood vessel remodeling	6.24e-04	1.00e+00	10.646	1	1	1
GO:0010711	negative regulation of collagen catabolic process	6.24e-04	1.00e+00	10.646	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	6.24e-04	1.00e+00	10.646	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	6.24e-04	1.00e+00	10.646	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	6.24e-04	1.00e+00	10.646	1	1	1
GO:0002020	protease binding	9.13e-04	1.00e+00	5.437	2	6	74
GO:0003723	RNA binding	9.98e-04	1.00e+00	3.813	3	18	342
GO:0071013	catalytic step 2 spliceosome	1.01e-03	1.00e+00	5.361	2	7	78
GO:0009786	regulation of asymmetric cell division	1.25e-03	1.00e+00	9.646	1	1	2
GO:0060242	contact inhibition	1.25e-03	1.00e+00	9.646	1	1	2
GO:0001649	osteoblast differentiation	1.41e-03	1.00e+00	5.123	2	5	92
GO:0010951	negative regulation of endopeptidase activity	1.79e-03	1.00e+00	4.946	2	6	104
GO:0034103	regulation of tissue remodeling	1.87e-03	1.00e+00	9.061	1	1	3
GO:0060913	cardiac cell fate determination	1.87e-03	1.00e+00	9.061	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.87e-03	1.00e+00	9.061	1	1	3
GO:0030529	ribonucleoprotein complex	2.08e-03	1.00e+00	4.839	2	5	112
GO:0010716	negative regulation of extracellular matrix disassembly	2.49e-03	1.00e+00	8.646	1	2	4
GO:0097452	GAIT complex	2.49e-03	1.00e+00	8.646	1	1	4
GO:0034273	ATG1/UKL1 signaling complex	2.49e-03	1.00e+00	8.646	1	1	4
GO:0001714	endodermal cell fate specification	3.12e-03	1.00e+00	8.324	1	1	5
GO:0048671	negative regulation of collateral sprouting	3.12e-03	1.00e+00	8.324	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	3.74e-03	1.00e+00	8.061	1	1	6
GO:0044212	transcription regulatory region DNA binding	4.60e-03	1.00e+00	4.254	2	17	168
GO:0043206	extracellular fibril organization	5.60e-03	1.00e+00	7.476	1	1	9
GO:0035413	positive regulation of catenin import into nucleus	6.22e-03	1.00e+00	7.324	1	2	10
GO:0010467	gene expression	6.76e-03	1.00e+00	2.845	3	45	669
GO:0060391	positive regulation of SMAD protein import into nucleus	6.85e-03	1.00e+00	7.187	1	4	11
GO:0034045	pre-autophagosomal structure membrane	7.47e-03	1.00e+00	7.061	1	2	12
GO:0035198	miRNA binding	7.47e-03	1.00e+00	7.061	1	1	12
GO:0008143	poly(A) binding	7.47e-03	1.00e+00	7.061	1	2	12
GO:0071480	cellular response to gamma radiation	8.09e-03	1.00e+00	6.946	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	8.09e-03	1.00e+00	6.946	1	2	13
GO:0001824	blastocyst development	9.32e-03	1.00e+00	6.739	1	2	15
GO:0043274	phospholipase binding	9.94e-03	1.00e+00	6.646	1	1	16
GO:0000166	nucleotide binding	1.06e-02	1.00e+00	3.629	2	13	259
GO:0048675	axon extension	1.30e-02	1.00e+00	6.254	1	2	21
GO:0036464	cytoplasmic ribonucleoprotein granule	1.36e-02	1.00e+00	6.187	1	2	22
GO:0071346	cellular response to interferon-gamma	1.43e-02	1.00e+00	6.123	1	1	23
GO:0010506	regulation of autophagy	1.43e-02	1.00e+00	6.123	1	2	23
GO:0035329	hippo signaling	1.61e-02	1.00e+00	5.946	1	5	26
GO:0000045	autophagic vacuole assembly	1.61e-02	1.00e+00	5.946	1	2	26
GO:0001540	beta-amyloid binding	1.67e-02	1.00e+00	5.891	1	1	27
GO:0042594	response to starvation	1.92e-02	1.00e+00	5.692	1	4	31
GO:1903507	negative regulation of nucleic acid-templated transcription	1.98e-02	1.00e+00	5.646	1	2	32
GO:0035019	somatic stem cell maintenance	2.47e-02	1.00e+00	5.324	1	6	40
GO:0017148	negative regulation of translation	2.47e-02	1.00e+00	5.324	1	2	40
GO:0031124	mRNA 3'-end processing	2.59e-02	1.00e+00	5.254	1	2	42
GO:0006366	transcription from RNA polymerase II promoter	2.65e-02	1.00e+00	2.935	2	30	419
GO:0008344	adult locomotory behavior	2.71e-02	1.00e+00	5.187	1	2	44
GO:0006369	termination of RNA polymerase II transcription	2.77e-02	1.00e+00	5.154	1	2	45
GO:0006952	defense response	2.90e-02	1.00e+00	5.092	1	2	47
GO:0009611	response to wounding	3.20e-02	1.00e+00	4.946	1	5	52
GO:0005515	protein binding	3.23e-02	1.00e+00	0.897	7	198	6024
GO:0003677	DNA binding	3.43e-02	1.00e+00	1.981	3	49	1218
GO:0000786	nucleosome	3.62e-02	1.00e+00	4.764	1	2	59
GO:0006406	mRNA export from nucleus	3.74e-02	1.00e+00	4.715	1	4	61
GO:0010468	regulation of gene expression	4.17e-02	1.00e+00	4.559	1	2	68
GO:0006334	nucleosome assembly	4.41e-02	1.00e+00	4.476	1	3	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	4.53e-02	1.00e+00	4.437	1	4	74
GO:0009653	anatomical structure morphogenesis	5.06e-02	1.00e+00	4.271	1	2	83
GO:0030659	cytoplasmic vesicle membrane	6.13e-02	1.00e+00	3.988	1	2	101
GO:0042981	regulation of apoptotic process	8.98e-02	1.00e+00	3.417	1	4	150
GO:0006974	cellular response to DNA damage stimulus	9.04e-02	1.00e+00	3.408	1	7	151
GO:0046777	protein autophosphorylation	9.44e-02	1.00e+00	3.342	1	4	158
GO:0016607	nuclear speck	1.02e-01	1.00e+00	3.220	1	12	172
GO:0005667	transcription factor complex	1.04e-01	1.00e+00	3.195	1	17	175
GO:0031625	ubiquitin protein ligase binding	1.06e-01	1.00e+00	3.170	1	5	178
GO:0003714	transcription corepressor activity	1.06e-01	1.00e+00	3.170	1	11	178
GO:0006367	transcription initiation from RNA polymerase II promoter	1.09e-01	1.00e+00	3.123	1	22	184
GO:0005615	extracellular space	1.16e-01	1.00e+00	1.744	2	20	957
GO:0005634	nucleus	1.20e-01	1.00e+00	0.814	5	159	4559
GO:0006355	regulation of transcription, DNA-templated	1.24e-01	1.00e+00	1.685	2	43	997
GO:0003713	transcription coactivator activity	1.39e-01	1.00e+00	2.757	1	24	237
GO:0008134	transcription factor binding	1.41e-01	1.00e+00	2.727	1	18	242
GO:0004674	protein serine/threonine kinase activity	1.77e-01	1.00e+00	2.379	1	6	308
GO:0005737	cytoplasm	1.87e-01	1.00e+00	0.767	4	124	3767
GO:0008283	cell proliferation	1.87e-01	1.00e+00	2.289	1	14	328
GO:0005524	ATP binding	1.91e-01	1.00e+00	1.304	2	31	1298
GO:0005829	cytosol	1.93e-01	1.00e+00	0.946	3	86	2496
GO:0043565	sequence-specific DNA binding	1.96e-01	1.00e+00	2.212	1	11	346
GO:0009986	cell surface	2.25e-01	1.00e+00	1.995	1	9	402
GO:0005730	nucleolus	2.73e-01	1.00e+00	0.966	2	66	1641
GO:0016020	membrane	2.83e-01	1.00e+00	0.931	2	46	1681
GO:0016032	viral process	2.88e-01	1.00e+00	1.585	1	26	534
GO:0005783	endoplasmic reticulum	2.98e-01	1.00e+00	1.527	1	13	556
GO:0003700	sequence-specific DNA binding transcription factor activity	3.61e-01	1.00e+00	1.197	1	39	699
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.97e-01	1.00e+00	1.022	1	41	789
GO:0007165	signal transduction	4.43e-01	1.00e+00	0.821	1	13	907
GO:0070062	extracellular vesicular exosome	4.56e-01	1.00e+00	0.417	2	57	2400
GO:0005576	extracellular region	4.56e-01	1.00e+00	0.767	1	13	942

chia-Fav

int-snw-1471

Statistics

Genes (9)

Interactions (10)

Related GO terms (103)