int-snw-10594

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.824	2.19e-15	5.54e-04	3.73e-03

chia-screen-data-Fav-int-snw-10594 subnetwork

Genes (13)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
TPR	7175	18	-2.638	3.072	28	Yes	Yes
PSMD2	5708	47	-4.172	3.157	386	Yes	Yes
LARS	51520	14	-2.574	3.157	105	Yes	Yes
[ PRPF8 ]	10594	1	-1.894	2.824	130	-	-
PXN	5829	19	-2.554	3.193	206	Yes	Yes
ZNF43	7594	4	-2.555	2.923	1	Yes	Yes
PHB	5245	15	-2.743	3.004	127	Yes	Yes
ODF2	4957	4	-2.568	2.923	3	Yes	Yes
APC	324	13	-2.293	3.004	353	Yes	-
SRSF3	6428	73	-2.992	3.538	54	Yes	-
KDM5C	8242	2	-2.040	2.842	45	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
SERPINB2	5055	1	-2.536	2.824	7	Yes	Yes

Interactions (12)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
KDM5C	8242	PRPF8	10594	pp	--	int.I2D: BioGrid_Yeast
APC	324	ODF2	4957	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
APC	324	PXN	5829	pp	--	int.I2D: MINT, MINT_Mouse; int.Mint: MI:0914(association)
APC	324	LARS	51520	pp	--	int.I2D: Jorgensen_EphR
APC	324	PRPF8	10594	pp	--	int.I2D: Jorgensen_EphR
APC	324	PHB	5245	pp	--	int.I2D: Jorgensen_EphR
SERPINB2	5055	PRPF8	10594	pp	--	int.I2D: HPRD; int.HPRD: in vivo, yeast 2-hybrid
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
PXN	5829	SRSF3	6428	pp	--	int.I2D: BIND
PSMD2	5708	LARS	51520	pp	--	int.I2D: BioGrid_Yeast
APC	324	ZNF43	7594	pp	--	int.I2D: IntAct, SOURAV_MAPK_LOW
APC	324	TPR	7175	pp	--	int.Intact: MI:0915(physical association); int.I2D: BioGrid, IntAct, SOURAV_MAPK_HIGH

Related GO terms (272)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	1.90e-04	1.00e+00	2.621	6	64	1082
GO:0007094	mitotic spindle assembly checkpoint	3.44e-04	1.00e+00	6.161	2	3	31
GO:0035019	somatic stem cell maintenance	5.74e-04	1.00e+00	5.794	2	6	40
GO:1901673	regulation of spindle assembly involved in mitosis	9.01e-04	1.00e+00	10.116	1	1	1
GO:0043578	nuclear matrix organization	9.01e-04	1.00e+00	10.116	1	1	1
GO:0010965	regulation of mitotic sister chromatid separation	9.01e-04	1.00e+00	10.116	1	1	1
GO:0051435	BH4 domain binding	9.01e-04	1.00e+00	10.116	1	1	1
GO:0006404	RNA import into nucleus	9.01e-04	1.00e+00	10.116	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	9.01e-04	1.00e+00	10.116	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	9.01e-04	1.00e+00	10.116	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	9.01e-04	1.00e+00	10.116	1	1	1
GO:0042483	negative regulation of odontogenesis	9.01e-04	1.00e+00	10.116	1	1	1
GO:0060795	cell fate commitment involved in formation of primary germ layer	9.01e-04	1.00e+00	10.116	1	1	1
GO:0030623	U5 snRNA binding	9.01e-04	1.00e+00	10.116	1	1	1
GO:0051171	regulation of nitrogen compound metabolic process	9.01e-04	1.00e+00	10.116	1	1	1
GO:0031453	positive regulation of heterochromatin assembly	9.01e-04	1.00e+00	10.116	1	1	1
GO:0005634	nucleus	1.03e-03	1.00e+00	1.283	10	159	4559
GO:0008013	beta-catenin binding	1.29e-03	1.00e+00	5.209	2	9	60
GO:0000776	kinetochore	1.42e-03	1.00e+00	5.138	2	5	63
GO:0006429	leucyl-tRNA aminoacylation	1.80e-03	1.00e+00	9.116	1	1	2
GO:0031990	mRNA export from nucleus in response to heat stress	1.80e-03	1.00e+00	9.116	1	2	2
GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	1.80e-03	1.00e+00	9.116	1	1	2
GO:0009786	regulation of asymmetric cell division	1.80e-03	1.00e+00	9.116	1	1	2
GO:0070840	dynein complex binding	1.80e-03	1.00e+00	9.116	1	1	2
GO:0046832	negative regulation of RNA export from nucleus	1.80e-03	1.00e+00	9.116	1	1	2
GO:0000189	MAPK import into nucleus	1.80e-03	1.00e+00	9.116	1	1	2
GO:0004823	leucine-tRNA ligase activity	1.80e-03	1.00e+00	9.116	1	1	2
GO:0009798	axis specification	1.80e-03	1.00e+00	9.116	1	1	2
GO:0010467	gene expression	2.34e-03	1.00e+00	2.730	4	45	669
GO:0042306	regulation of protein import into nucleus	2.70e-03	1.00e+00	8.531	1	2	3
GO:0060913	cardiac cell fate determination	2.70e-03	1.00e+00	8.531	1	1	3
GO:0006405	RNA export from nucleus	2.70e-03	1.00e+00	8.531	1	2	3
GO:0003130	BMP signaling pathway involved in heart induction	2.70e-03	1.00e+00	8.531	1	1	3
GO:0032453	histone demethylase activity (H3-K4 specific)	3.60e-03	1.00e+00	8.116	1	1	4
GO:0006999	nuclear pore organization	3.60e-03	1.00e+00	8.116	1	1	4
GO:0044615	nuclear pore nuclear basket	3.60e-03	1.00e+00	8.116	1	1	4
GO:0019887	protein kinase regulator activity	3.60e-03	1.00e+00	8.116	1	1	4
GO:0001714	endodermal cell fate specification	4.50e-03	1.00e+00	7.794	1	1	5
GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	4.50e-03	1.00e+00	7.794	1	1	5
GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	4.50e-03	1.00e+00	7.794	1	2	5
GO:0010793	regulation of mRNA export from nucleus	4.50e-03	1.00e+00	7.794	1	1	5
GO:0070849	response to epidermal growth factor	4.50e-03	1.00e+00	7.794	1	1	5
GO:0000278	mitotic cell cycle	4.62e-03	1.00e+00	3.090	3	15	391
GO:0030858	positive regulation of epithelial cell differentiation	5.40e-03	1.00e+00	7.531	1	1	6
GO:0050847	progesterone receptor signaling pathway	5.40e-03	1.00e+00	7.531	1	2	6
GO:0005682	U5 snRNP	5.40e-03	1.00e+00	7.531	1	1	6
GO:0034720	histone H3-K4 demethylation	5.40e-03	1.00e+00	7.531	1	1	6
GO:0001520	outer dense fiber	5.40e-03	1.00e+00	7.531	1	1	6
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	5.40e-03	1.00e+00	7.531	1	1	6
GO:0017070	U6 snRNA binding	5.40e-03	1.00e+00	7.531	1	1	6
GO:0030027	lamellipodium	5.46e-03	1.00e+00	4.150	2	7	125
GO:0007091	metaphase/anaphase transition of mitotic cell cycle	6.29e-03	1.00e+00	7.308	1	2	7
GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development	6.29e-03	1.00e+00	7.308	1	1	7
GO:0046825	regulation of protein export from nucleus	6.29e-03	1.00e+00	7.308	1	2	7
GO:0071354	cellular response to interleukin-6	6.29e-03	1.00e+00	7.308	1	2	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	6.29e-03	1.00e+00	7.308	1	2	7
GO:0002161	aminoacyl-tRNA editing activity	6.29e-03	1.00e+00	7.308	1	2	7
GO:0045670	regulation of osteoclast differentiation	7.19e-03	1.00e+00	7.116	1	2	8
GO:0051292	nuclear pore complex assembly	7.19e-03	1.00e+00	7.116	1	4	8
GO:0035457	cellular response to interferon-alpha	7.19e-03	1.00e+00	7.116	1	1	8
GO:0007172	signal complex assembly	7.19e-03	1.00e+00	7.116	1	1	8
GO:0060396	growth hormone receptor signaling pathway	7.19e-03	1.00e+00	7.116	1	1	8
GO:0005737	cytoplasm	7.50e-03	1.00e+00	1.236	8	124	3767
GO:0042981	regulation of apoptotic process	7.77e-03	1.00e+00	3.887	2	4	150
GO:0045667	regulation of osteoblast differentiation	8.09e-03	1.00e+00	6.946	1	1	9
GO:0042405	nuclear inclusion body	8.09e-03	1.00e+00	6.946	1	2	9
GO:0006450	regulation of translational fidelity	8.09e-03	1.00e+00	6.946	1	2	9
GO:0043495	protein anchor	8.09e-03	1.00e+00	6.946	1	1	9
GO:0010944	negative regulation of transcription by competitive promoter binding	8.09e-03	1.00e+00	6.946	1	1	9
GO:0031274	positive regulation of pseudopodium assembly	8.98e-03	1.00e+00	6.794	1	2	10
GO:0035413	positive regulation of catenin import into nucleus	8.98e-03	1.00e+00	6.794	1	2	10
GO:0030877	beta-catenin destruction complex	8.98e-03	1.00e+00	6.794	1	2	10
GO:0000398	mRNA splicing, via spliceosome	9.23e-03	1.00e+00	3.758	2	15	164
GO:0044212	transcription regulatory region DNA binding	9.67e-03	1.00e+00	3.723	2	17	168
GO:0051010	microtubule plus-end binding	9.87e-03	1.00e+00	6.656	1	1	11
GO:0017166	vinculin binding	9.87e-03	1.00e+00	6.656	1	1	11
GO:0070530	K63-linked polyubiquitin binding	9.87e-03	1.00e+00	6.656	1	2	11
GO:0031116	positive regulation of microtubule polymerization	9.87e-03	1.00e+00	6.656	1	1	11
GO:0000244	spliceosomal tri-snRNP complex assembly	9.87e-03	1.00e+00	6.656	1	1	11
GO:0060391	positive regulation of SMAD protein import into nucleus	9.87e-03	1.00e+00	6.656	1	4	11
GO:0016607	nuclear speck	1.01e-02	1.00e+00	3.689	2	12	172
GO:0032886	regulation of microtubule-based process	1.08e-02	1.00e+00	6.531	1	1	12
GO:0045947	negative regulation of translational initiation	1.08e-02	1.00e+00	6.531	1	2	12
GO:0045295	gamma-catenin binding	1.08e-02	1.00e+00	6.531	1	1	12
GO:0034399	nuclear periphery	1.08e-02	1.00e+00	6.531	1	5	12
GO:0005838	proteasome regulatory particle	1.08e-02	1.00e+00	6.531	1	1	12
GO:0035198	miRNA binding	1.08e-02	1.00e+00	6.531	1	1	12
GO:0005515	protein binding	1.11e-02	1.00e+00	0.881	10	198	6024
GO:0042789	mRNA transcription from RNA polymerase II promoter	1.17e-02	1.00e+00	6.415	1	2	13
GO:0060766	negative regulation of androgen receptor signaling pathway	1.17e-02	1.00e+00	6.415	1	3	13
GO:0044295	axonal growth cone	1.17e-02	1.00e+00	6.415	1	1	13
GO:0051019	mitogen-activated protein kinase binding	1.17e-02	1.00e+00	6.415	1	2	13
GO:0043409	negative regulation of MAPK cascade	1.17e-02	1.00e+00	6.415	1	2	13
GO:0005868	cytoplasmic dynein complex	1.17e-02	1.00e+00	6.415	1	1	13
GO:0030234	enzyme regulator activity	1.17e-02	1.00e+00	6.415	1	2	13
GO:0046827	positive regulation of protein export from nucleus	1.17e-02	1.00e+00	6.415	1	1	13
GO:0044822	poly(A) RNA binding	1.20e-02	1.00e+00	2.071	4	50	1056
GO:0035371	microtubule plus-end	1.26e-02	1.00e+00	6.308	1	1	14
GO:0034614	cellular response to reactive oxygen species	1.26e-02	1.00e+00	6.308	1	2	14
GO:0005487	nucleocytoplasmic transporter activity	1.26e-02	1.00e+00	6.308	1	3	14
GO:0042307	positive regulation of protein import into nucleus	1.34e-02	1.00e+00	6.209	1	4	15
GO:0001824	blastocyst development	1.34e-02	1.00e+00	6.209	1	2	15
GO:0016706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	1.34e-02	1.00e+00	6.209	1	1	15
GO:0007026	negative regulation of microtubule depolymerization	1.43e-02	1.00e+00	6.116	1	1	16
GO:0042176	regulation of protein catabolic process	1.43e-02	1.00e+00	6.116	1	2	16
GO:0046716	muscle cell cellular homeostasis	1.43e-02	1.00e+00	6.116	1	1	16
GO:0043274	phospholipase binding	1.43e-02	1.00e+00	6.116	1	1	16
GO:0051276	chromosome organization	1.43e-02	1.00e+00	6.116	1	2	16
GO:0090316	positive regulation of intracellular protein transport	1.52e-02	1.00e+00	6.028	1	2	17
GO:0022624	proteasome accessory complex	1.52e-02	1.00e+00	6.028	1	1	17
GO:0042730	fibrinolysis	1.61e-02	1.00e+00	5.946	1	3	18
GO:0031122	cytoplasmic microtubule organization	1.61e-02	1.00e+00	5.946	1	1	18
GO:0045736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	1.70e-02	1.00e+00	5.868	1	2	19
GO:0008380	RNA splicing	1.73e-02	1.00e+00	3.283	2	22	228
GO:0048041	focal adhesion assembly	1.88e-02	1.00e+00	5.723	1	1	21
GO:0009954	proximal/distal pattern formation	1.88e-02	1.00e+00	5.723	1	1	21
GO:0016575	histone deacetylation	1.88e-02	1.00e+00	5.723	1	3	21
GO:0000281	mitotic cytokinesis	1.88e-02	1.00e+00	5.723	1	2	21
GO:0045296	cadherin binding	2.14e-02	1.00e+00	5.531	1	3	24
GO:1902017	regulation of cilium assembly	2.14e-02	1.00e+00	5.531	1	2	24
GO:0006611	protein export from nucleus	2.23e-02	1.00e+00	5.472	1	3	25
GO:0000375	RNA splicing, via transesterification reactions	2.23e-02	1.00e+00	5.472	1	3	25
GO:0072372	primary cilium	2.32e-02	1.00e+00	5.415	1	1	26
GO:0048754	branching morphogenesis of an epithelial tube	2.41e-02	1.00e+00	5.361	1	1	27
GO:0015631	tubulin binding	2.41e-02	1.00e+00	5.361	1	2	27
GO:0005875	microtubule associated complex	2.50e-02	1.00e+00	5.308	1	1	28
GO:0030162	regulation of proteolysis	2.50e-02	1.00e+00	5.308	1	2	28
GO:0034605	cellular response to heat	2.50e-02	1.00e+00	5.308	1	1	28
GO:0071897	DNA biosynthetic process	2.50e-02	1.00e+00	5.308	1	1	28
GO:0070830	tight junction assembly	2.50e-02	1.00e+00	5.308	1	1	28
GO:0005913	cell-cell adherens junction	2.58e-02	1.00e+00	5.258	1	3	29
GO:0030032	lamellipodium assembly	2.58e-02	1.00e+00	5.258	1	1	29
GO:0072686	mitotic spindle	2.58e-02	1.00e+00	5.258	1	3	29
GO:0006606	protein import into nucleus	2.67e-02	1.00e+00	5.209	1	2	30
GO:0031647	regulation of protein stability	2.67e-02	1.00e+00	5.209	1	4	30
GO:0010827	regulation of glucose transport	2.67e-02	1.00e+00	5.209	1	4	30
GO:0009953	dorsal/ventral pattern formation	2.76e-02	1.00e+00	5.161	1	2	31
GO:0033077	T cell differentiation in thymus	2.94e-02	1.00e+00	5.071	1	1	33
GO:0031072	heat shock protein binding	2.94e-02	1.00e+00	5.071	1	2	33
GO:0001942	hair follicle development	3.11e-02	1.00e+00	4.986	1	2	35
GO:0007077	mitotic nuclear envelope disassembly	3.20e-02	1.00e+00	4.946	1	4	36
GO:0019901	protein kinase binding	3.20e-02	1.00e+00	2.807	2	18	317
GO:0034446	substrate adhesion-dependent cell spreading	3.20e-02	1.00e+00	4.946	1	2	36
GO:0048538	thymus development	3.20e-02	1.00e+00	4.946	1	2	36
GO:0005813	centrosome	3.37e-02	1.00e+00	2.767	2	7	326
GO:0008645	hexose transport	3.46e-02	1.00e+00	4.830	1	4	39
GO:0051781	positive regulation of cell division	3.46e-02	1.00e+00	4.830	1	1	39
GO:0005881	cytoplasmic microtubule	3.55e-02	1.00e+00	4.794	1	1	40
GO:0045785	positive regulation of cell adhesion	3.55e-02	1.00e+00	4.794	1	2	40
GO:0007286	spermatid development	3.63e-02	1.00e+00	4.758	1	1	41
GO:0006418	tRNA aminoacylation for protein translation	3.72e-02	1.00e+00	4.723	1	3	42
GO:0031124	mRNA 3'-end processing	3.72e-02	1.00e+00	4.723	1	2	42
GO:0019898	extrinsic component of membrane	3.72e-02	1.00e+00	4.723	1	2	42
GO:0008285	negative regulation of cell proliferation	3.90e-02	1.00e+00	2.652	2	10	353
GO:0006369	termination of RNA polymerase II transcription	3.98e-02	1.00e+00	4.624	1	2	45
GO:0048511	rhythmic process	3.98e-02	1.00e+00	4.624	1	4	45
GO:0016328	lateral plasma membrane	4.07e-02	1.00e+00	4.592	1	3	46
GO:0006921	cellular component disassembly involved in execution phase of apoptosis	4.16e-02	1.00e+00	4.561	1	2	47
GO:0007155	cell adhesion	4.23e-02	1.00e+00	2.588	2	5	369
GO:0006521	regulation of cellular amino acid metabolic process	4.42e-02	1.00e+00	4.472	1	1	50
GO:0045732	positive regulation of protein catabolic process	4.42e-02	1.00e+00	4.472	1	1	50
GO:0060041	retina development in camera-type eye	4.50e-02	1.00e+00	4.443	1	2	51
GO:0009611	response to wounding	4.59e-02	1.00e+00	4.415	1	5	52
GO:0015758	glucose transport	4.85e-02	1.00e+00	4.334	1	4	55
GO:0001725	stress fiber	4.85e-02	1.00e+00	4.334	1	4	55
GO:0036064	ciliary basal body	5.02e-02	1.00e+00	4.283	1	2	57
GO:0005643	nuclear pore	5.02e-02	1.00e+00	4.283	1	11	57
GO:0000502	proteasome complex	5.11e-02	1.00e+00	4.258	1	3	58
GO:0045892	negative regulation of transcription, DNA-templated	5.18e-02	1.00e+00	2.426	2	24	413
GO:0006366	transcription from RNA polymerase II promoter	5.32e-02	1.00e+00	2.405	2	30	419
GO:0006406	mRNA export from nucleus	5.36e-02	1.00e+00	4.185	1	4	61
GO:0043066	negative regulation of apoptotic process	5.43e-02	1.00e+00	2.388	2	16	424
GO:0004867	serine-type endopeptidase inhibitor activity	5.53e-02	1.00e+00	4.138	1	3	63
GO:0006355	regulation of transcription, DNA-templated	5.59e-02	1.00e+00	1.739	3	43	997
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	5.62e-02	1.00e+00	4.116	1	1	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	5.71e-02	1.00e+00	4.093	1	2	65
GO:0007409	axonogenesis	5.71e-02	1.00e+00	4.093	1	2	65
GO:0005829	cytosol	5.88e-02	1.00e+00	1.152	5	86	2496
GO:0010468	regulation of gene expression	5.96e-02	1.00e+00	4.028	1	2	68
GO:0034329	cell junction assembly	5.96e-02	1.00e+00	4.028	1	3	68
GO:0032587	ruffle membrane	6.13e-02	1.00e+00	3.986	1	3	70
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.13e-02	1.00e+00	3.986	1	2	70
GO:0042826	histone deacetylase binding	6.30e-02	1.00e+00	3.946	1	4	72
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	6.30e-02	1.00e+00	3.946	1	1	72
GO:0003729	mRNA binding	6.30e-02	1.00e+00	3.946	1	4	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	6.47e-02	1.00e+00	3.906	1	4	74
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	6.47e-02	1.00e+00	3.906	1	2	74
GO:0060070	canonical Wnt signaling pathway	6.56e-02	1.00e+00	3.887	1	4	75
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	6.56e-02	1.00e+00	3.887	1	1	75
GO:0017137	Rab GTPase binding	6.64e-02	1.00e+00	3.868	1	1	76
GO:0001822	kidney development	6.81e-02	1.00e+00	3.830	1	3	78
GO:0007229	integrin-mediated signaling pathway	6.81e-02	1.00e+00	3.830	1	3	78
GO:0071013	catalytic step 2 spliceosome	6.81e-02	1.00e+00	3.830	1	7	78
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	6.89e-02	1.00e+00	3.812	1	2	79
GO:0005814	centriole	6.89e-02	1.00e+00	3.812	1	2	79
GO:0009653	anatomical structure morphogenesis	7.23e-02	1.00e+00	3.741	1	2	83
GO:0009952	anterior/posterior pattern specification	7.23e-02	1.00e+00	3.741	1	4	83
GO:0005923	tight junction	7.48e-02	1.00e+00	3.689	1	2	86
GO:0090090	negative regulation of canonical Wnt signaling pathway	7.48e-02	1.00e+00	3.689	1	8	86
GO:0000922	spindle pole	7.57e-02	1.00e+00	3.673	1	4	87
GO:0006936	muscle contraction	7.57e-02	1.00e+00	3.673	1	3	87
GO:0000187	activation of MAPK activity	7.82e-02	1.00e+00	3.624	1	3	90
GO:0007010	cytoskeleton organization	7.90e-02	1.00e+00	3.608	1	4	91
GO:0006928	cellular component movement	7.90e-02	1.00e+00	3.608	1	3	91
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	7.99e-02	1.00e+00	3.592	1	1	92
GO:0001649	osteoblast differentiation	7.99e-02	1.00e+00	3.592	1	5	92
GO:0016032	viral process	8.15e-02	1.00e+00	2.055	2	26	534
GO:0005178	integrin binding	8.32e-02	1.00e+00	3.531	1	4	96
GO:0006915	apoptotic process	8.71e-02	1.00e+00	1.999	2	12	555
GO:0008360	regulation of cell shape	8.90e-02	1.00e+00	3.429	1	4	103
GO:0010951	negative regulation of endopeptidase activity	8.98e-02	1.00e+00	3.415	1	6	104
GO:0005938	cell cortex	8.98e-02	1.00e+00	3.415	1	5	104
GO:0003677	DNA binding	9.07e-02	1.00e+00	1.450	3	49	1218
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	9.12e-02	1.00e+00	1.961	2	37	570
GO:0030308	negative regulation of cell growth	9.48e-02	1.00e+00	3.334	1	6	110
GO:0006461	protein complex assembly	9.56e-02	1.00e+00	3.321	1	4	111
GO:0005635	nuclear envelope	9.72e-02	1.00e+00	3.295	1	5	113
GO:0000209	protein polyubiquitination	9.97e-02	1.00e+00	3.258	1	3	116
GO:0007050	cell cycle arrest	1.06e-01	1.00e+00	3.161	1	5	124
GO:0007179	transforming growth factor beta receptor signaling pathway	1.09e-01	1.00e+00	3.116	1	11	128
GO:0016477	cell migration	1.09e-01	1.00e+00	3.116	1	4	128
GO:0030335	positive regulation of cell migration	1.09e-01	1.00e+00	3.127	1	5	127
GO:0005215	transporter activity	1.11e-01	1.00e+00	3.093	1	3	130
GO:0018108	peptidyl-tyrosine phosphorylation	1.13e-01	1.00e+00	3.071	1	4	132
GO:0000086	G2/M transition of mitotic cell cycle	1.16e-01	1.00e+00	3.028	1	4	136
GO:0008017	microtubule binding	1.25e-01	1.00e+00	2.916	1	2	147
GO:0000082	G1/S transition of mitotic cell cycle	1.26e-01	1.00e+00	2.896	1	3	149
GO:0005198	structural molecule activity	1.27e-01	1.00e+00	2.887	1	3	150
GO:0006974	cellular response to DNA damage stimulus	1.28e-01	1.00e+00	2.877	1	7	151
GO:0003700	sequence-specific DNA binding transcription factor activity	1.29e-01	1.00e+00	1.666	2	39	699
GO:0006397	mRNA processing	1.35e-01	1.00e+00	2.794	1	10	160
GO:0031965	nuclear membrane	1.41e-01	1.00e+00	2.723	1	10	168
GO:0034641	cellular nitrogen compound metabolic process	1.44e-01	1.00e+00	2.698	1	2	171
GO:0005667	transcription factor complex	1.47e-01	1.00e+00	2.664	1	17	175
GO:0031625	ubiquitin protein ligase binding	1.49e-01	1.00e+00	2.640	1	5	178
GO:0007173	epidermal growth factor receptor signaling pathway	1.58e-01	1.00e+00	2.553	1	5	189
GO:0019221	cytokine-mediated signaling pathway	1.82e-01	1.00e+00	2.328	1	8	221
GO:0016071	mRNA metabolic process	1.83e-01	1.00e+00	2.315	1	8	223
GO:0007067	mitotic nuclear division	1.86e-01	1.00e+00	2.289	1	6	227
GO:0016020	membrane	1.87e-01	1.00e+00	0.986	3	46	1681
GO:0007165	signal transduction	1.95e-01	1.00e+00	1.291	2	13	907
GO:0008134	transcription factor binding	1.98e-01	1.00e+00	2.197	1	18	242
GO:0016070	RNA metabolic process	2.01e-01	1.00e+00	2.167	1	8	247
GO:0005874	microtubule	2.03e-01	1.00e+00	2.156	1	7	249
GO:0005975	carbohydrate metabolic process	2.06e-01	1.00e+00	2.133	1	8	253
GO:0000166	nucleotide binding	2.10e-01	1.00e+00	2.099	1	13	259
GO:0043065	positive regulation of apoptotic process	2.16e-01	1.00e+00	2.050	1	7	268
GO:0005743	mitochondrial inner membrane	2.23e-01	1.00e+00	2.002	1	6	277
GO:0019899	enzyme binding	2.23e-01	1.00e+00	2.002	1	9	277
GO:0008270	zinc ion binding	2.25e-01	1.00e+00	1.154	2	27	997
GO:0007275	multicellular organismal development	2.50e-01	1.00e+00	1.812	1	7	316
GO:0003682	chromatin binding	2.58e-01	1.00e+00	1.762	1	19	327
GO:0003723	RNA binding	2.68e-01	1.00e+00	1.698	1	18	342
GO:0043565	sequence-specific DNA binding	2.71e-01	1.00e+00	1.681	1	11	346
GO:0005925	focal adhesion	2.84e-01	1.00e+00	1.600	1	9	366
GO:0044281	small molecule metabolic process	2.99e-01	1.00e+00	0.874	2	20	1211
GO:0055114	oxidation-reduction process	3.19e-01	1.00e+00	1.401	1	10	420
GO:0055085	transmembrane transport	3.29e-01	1.00e+00	1.351	1	8	435
GO:0007596	blood coagulation	3.41e-01	1.00e+00	1.286	1	11	455
GO:0045893	positive regulation of transcription, DNA-templated	3.55e-01	1.00e+00	1.215	1	24	478
GO:0006351	transcription, DNA-templated	3.80e-01	1.00e+00	0.618	2	57	1446
GO:0005886	plasma membrane	4.19e-01	1.00e+00	0.366	3	49	2582
GO:0042803	protein homodimerization activity	4.22e-01	1.00e+00	0.899	1	19	595
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	5.19e-01	1.00e+00	0.492	1	41	789
GO:0005887	integral component of plasma membrane	5.62e-01	1.00e+00	0.321	1	10	888
GO:0005576	extracellular region	5.85e-01	1.00e+00	0.236	1	13	942
GO:0005615	extracellular space	5.91e-01	1.00e+00	0.213	1	20	957
GO:0005739	mitochondrion	6.06e-01	1.00e+00	0.153	1	23	998
GO:0070062	extracellular vesicular exosome	6.63e-01	1.00e+00	-0.113	2	57	2400
GO:0005524	ATP binding	7.07e-01	1.00e+00	-0.226	1	31	1298
GO:0046872	metal ion binding	7.09e-01	1.00e+00	-0.236	1	29	1307
GO:0005730	nucleolus	7.92e-01	1.00e+00	-0.565	1	66	1641

chia-Fav

int-snw-10594

Statistics

Genes (13)

Interactions (12)

Related GO terms (272)