int-snw-10482

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.538	3.92e-24	8.32e-09	1.24e-06

chia-screen-data-Fav-int-snw-10482 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
YAP1	10413	94	-4.256	3.538	53	Yes	-
[ NXF1 ]	10482	10	-2.426	3.538	65	Yes	Yes
SRSF3	6428	73	-2.992	3.538	54	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
SRSF3	6428	NXF1	10482	pp	--	int.I2D: MINT, HPRD; int.Mint: MI:0407(direct interaction), MI:0915(physical association)
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
HNRNPU	3192	NXF1	10482	pp	--	int.Intact: MI:0914(association)
POU5F1	5460	SRSF3	6428	pp	--	int.I2D: BioGrid
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse

Related GO terms (70)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0005654	nucleoplasm	2.36e-06	3.40e-02	3.737	5	64	1082
GO:0010467	gene expression	2.21e-05	3.19e-01	4.108	4	45	669
GO:0044822	poly(A) RNA binding	1.35e-04	1.00e+00	3.450	4	50	1056
GO:0006406	mRNA export from nucleus	1.75e-04	1.00e+00	6.563	2	4	61
GO:0060795	cell fate commitment involved in formation of primary germ layer	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	3.47e-04	1.00e+00	11.494	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	3.47e-04	1.00e+00	11.494	1	1	1
GO:0009786	regulation of asymmetric cell division	6.93e-04	1.00e+00	10.494	1	1	2
GO:0060242	contact inhibition	6.93e-04	1.00e+00	10.494	1	1	2
GO:0060913	cardiac cell fate determination	1.04e-03	1.00e+00	9.909	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.04e-03	1.00e+00	9.909	1	1	3
GO:0000398	mRNA splicing, via spliceosome	1.26e-03	1.00e+00	5.137	2	15	164
GO:0044212	transcription regulatory region DNA binding	1.32e-03	1.00e+00	5.102	2	17	168
GO:0016607	nuclear speck	1.38e-03	1.00e+00	5.068	2	12	172
GO:0001714	endodermal cell fate specification	1.73e-03	1.00e+00	9.172	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	1.73e-03	1.00e+00	9.172	1	2	5
GO:0070937	CRD-mediated mRNA stability complex	2.08e-03	1.00e+00	8.909	1	3	6
GO:0008380	RNA splicing	2.41e-03	1.00e+00	4.661	2	22	228
GO:0016973	poly(A)+ mRNA export from nucleus	2.77e-03	1.00e+00	8.494	1	1	8
GO:0000166	nucleotide binding	3.10e-03	1.00e+00	4.477	2	13	259
GO:0042405	nuclear inclusion body	3.12e-03	1.00e+00	8.324	1	2	9
GO:0035413	positive regulation of catenin import into nucleus	3.46e-03	1.00e+00	8.172	1	2	10
GO:0060391	positive regulation of SMAD protein import into nucleus	3.81e-03	1.00e+00	8.035	1	4	11
GO:0035198	miRNA binding	4.15e-03	1.00e+00	7.909	1	1	12
GO:0071480	cellular response to gamma radiation	4.50e-03	1.00e+00	7.794	1	1	13
GO:0042789	mRNA transcription from RNA polymerase II promoter	4.50e-03	1.00e+00	7.794	1	2	13
GO:0000346	transcription export complex	4.50e-03	1.00e+00	7.794	1	1	13
GO:0005487	nucleocytoplasmic transporter activity	4.84e-03	1.00e+00	7.687	1	3	14
GO:0001824	blastocyst development	5.19e-03	1.00e+00	7.587	1	2	15
GO:0003723	RNA binding	5.35e-03	1.00e+00	4.076	2	18	342
GO:0043274	phospholipase binding	5.54e-03	1.00e+00	7.494	1	1	16
GO:0036464	cytoplasmic ribonucleoprotein granule	7.60e-03	1.00e+00	7.035	1	2	22
GO:0006366	transcription from RNA polymerase II promoter	7.94e-03	1.00e+00	3.783	2	30	419
GO:0035329	hippo signaling	8.98e-03	1.00e+00	6.794	1	5	26
GO:1903507	negative regulation of nucleic acid-templated transcription	1.10e-02	1.00e+00	6.494	1	2	32
GO:0005515	protein binding	1.27e-02	1.00e+00	1.260	5	198	6024
GO:0035019	somatic stem cell maintenance	1.38e-02	1.00e+00	6.172	1	6	40
GO:0031124	mRNA 3'-end processing	1.45e-02	1.00e+00	6.102	1	2	42
GO:0006369	termination of RNA polymerase II transcription	1.55e-02	1.00e+00	6.002	1	2	45
GO:0009611	response to wounding	1.79e-02	1.00e+00	5.794	1	5	52
GO:0005643	nuclear pore	1.96e-02	1.00e+00	5.661	1	11	57
GO:0006396	RNA processing	2.03e-02	1.00e+00	5.612	1	5	59
GO:0010468	regulation of gene expression	2.34e-02	1.00e+00	5.407	1	2	68
GO:0003729	mRNA binding	2.47e-02	1.00e+00	5.324	1	4	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	2.54e-02	1.00e+00	5.285	1	4	74
GO:0071013	catalytic step 2 spliceosome	2.68e-02	1.00e+00	5.209	1	7	78
GO:0009653	anatomical structure morphogenesis	2.84e-02	1.00e+00	5.119	1	2	83
GO:0001649	osteoblast differentiation	3.15e-02	1.00e+00	4.971	1	5	92
GO:0030529	ribonucleoprotein complex	3.82e-02	1.00e+00	4.687	1	5	112
GO:0005829	cytosol	3.93e-02	1.00e+00	1.794	3	86	2496
GO:0006355	regulation of transcription, DNA-templated	4.15e-02	1.00e+00	2.533	2	43	997
GO:0006974	cellular response to DNA damage stimulus	5.13e-02	1.00e+00	4.256	1	7	151
GO:0005667	transcription factor complex	5.92e-02	1.00e+00	4.043	1	17	175
GO:0003677	DNA binding	6.00e-02	1.00e+00	2.244	2	49	1218
GO:0031625	ubiquitin protein ligase binding	6.02e-02	1.00e+00	4.018	1	5	178
GO:0003714	transcription corepressor activity	6.02e-02	1.00e+00	4.018	1	11	178
GO:0006367	transcription initiation from RNA polymerase II promoter	6.22e-02	1.00e+00	3.971	1	22	184
GO:0003713	transcription coactivator activity	7.95e-02	1.00e+00	3.605	1	24	237
GO:0008134	transcription factor binding	8.11e-02	1.00e+00	3.575	1	18	242
GO:0008283	cell proliferation	1.09e-01	1.00e+00	3.137	1	14	328
GO:0043565	sequence-specific DNA binding	1.14e-01	1.00e+00	3.060	1	11	346
GO:0005737	cytoplasm	1.16e-01	1.00e+00	1.200	3	124	3767
GO:0009986	cell surface	1.32e-01	1.00e+00	2.843	1	9	402
GO:0016032	viral process	1.72e-01	1.00e+00	2.433	1	26	534
GO:0005634	nucleus	1.85e-01	1.00e+00	0.925	3	159	4559
GO:0003700	sequence-specific DNA binding transcription factor activity	2.20e-01	1.00e+00	2.045	1	39	699
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.45e-01	1.00e+00	1.870	1	41	789
GO:0005524	ATP binding	3.76e-01	1.00e+00	1.152	1	31	1298
GO:0016020	membrane	4.62e-01	1.00e+00	0.779	1	46	1681

chia-Fav

int-snw-10482

Statistics

Genes (5)

Interactions (5)

Related GO terms (70)