meta-int-snw-5522

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-4522 wolf-screen-ratio-mammosphere-adherent 0.815 1.50e-06 3.75e-03 6.95e-03 14 12
int-snw-5522 wolf-screen-ratio-mammosphere-adherent 0.923 4.44e-15 3.15e-03 4.76e-02 15 14
reg-snw-56655 wolf-screen-ratio-mammosphere-adherent 0.828 9.29e-07 2.91e-03 5.53e-03 8 7
reg-snw-5925 wolf-screen-ratio-mammosphere-adherent 0.802 2.42e-06 4.82e-03 8.69e-03 8 5
reg-snw-10213 wolf-screen-ratio-mammosphere-adherent 0.815 1.49e-06 3.74e-03 6.93e-03 7 6
wolf-screen-ratio-mammosphere-adherent-meta-int-snw-5522 subnetwork

Genes (38)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
PSMA3 5684 900.5330.815238Yes-
PPCS 79717 31-0.5690.8022-Yes
PSMA2 5683 1121.0931.106108Yes-
PHB2 11331 430.8290.956151Yes-
POLR2F 5435 620.8910.95626Yes-
VARS 7407 860.5491.002204Yes-
TFRC 7037 310.7300.80217--
RPA2 6118 961.2501.15176Yes-
RB1 5925 31-0.1020.802351--
PSMD1 5707 860.8360.830118Yes-
EEF2 1938 640.8901.043301Yes-
PPP2R1A 5518 190.6440.985249Yes-
EFTUD2 9343 930.8830.956108Yes-
PSMD14 10213 440.2990.81532--
TUBG1 7283 980.9740.97391Yes-
PSMD11 5717 1241.0951.106218Yes-
HSPD1 3329 700.9131.035325Yes-
PRMT3 10196 490.4310.81526--
MTHFD1 4522 490.1940.81526Yes-
RBX1 9978 1151.1850.934148Yes-
PPIE 10450 310.5670.80241--
HNRNPC 3183 1081.8120.973181Yes-
PSMB7 5695 1180.9820.93490Yes-
PSMA1 5682 1000.9960.878152Yes-
EIF4A1 1973 60.8660.98171Yes-
OGDH 4967 720.8470.802126Yes-
POLE4 56655 630.1770.82856--
PSMB3 5691 640.6680.90119Yes-
RPSA 3921 1201.3271.151152Yes-
RPA1 6117 510.4250.86574--
PGD 5226 891.2011.106152Yes-
ACO2 50 651.0001.076191Yes-
RUVBL1 8607 950.7200.973469Yes-
PSMD3 5709 1000.9861.106201Yes-
PSMB2 5690 1160.8770.956169Yes-
ACTB 60 1341.1531.151610Yes-
RUVBL2 10856 950.6930.956532Yes-
PPP2R2C 5522 5-0.2340.92319--

Interactions (167)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMA3 5684 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, Krogan_Core
HNRNPC 3183 PSMA3 5684 pp -- int.I2D: BioGrid
EEF2 1938 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
EEF2 1938 PGD 5226 pp -- int.I2D: BioGrid_Yeast
ACO2 50 RPA1 6117 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
PSMA1 5682 PSMB2 5690 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
EEF2 1938 HSPD1 3329 pp -- int.I2D: YeastLow, YeastMedium
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
PPP2R1A 5518 PSMB3 5691 pp -- int.I2D: IntAct_Mouse
ACO2 50 OGDH 4967 pp -- int.I2D: YeastLow
RB1 5925 PPCS 79717 pd > reg.pazar.txt: no annot
EFTUD2 9343 RUVBL2 10856 pd < reg.ITFP.txt: no annot
EFTUD2 9343 RUVBL2 10856 pp -- int.I2D: BioGrid
MTHFD1 4522 PSMA3 5684 pp -- int.I2D: BioGrid
EEF2 1938 PSMB3 5691 pp -- int.I2D: IntAct_Fly, BioGrid_Fly, BIND_Fly, FlyLow, MINT_Fly
RB1 5925 RPA2 6118 pd > reg.pazar.txt: no annot
PSMD1 5707 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, MINT_Yeast, Krogan_Core
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
ACTB 60 HSPD1 3329 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, YeastLow
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PSMB3 5691 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPA1 6117 RUVBL1 8607 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
RPA1 6117 VARS 7407 pp -- int.I2D: YeastLow
PSMB2 5690 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMB3 5691 PSMD3 5709 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PPP2R1A 5518 PSMA1 5682 pp -- int.I2D: IntAct_Mouse
PSMA3 5684 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMD14 10213 pp -- int.I2D: BioGrid, BioGrid_Yeast
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
PPP2R1A 5518 PHB2 11331 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association);
int.I2D: IntAct
PGD 5226 RB1 5925 pd < reg.pazar.txt: no annot
ACO2 50 HSPD1 3329 pp -- int.I2D: IntAct_Yeast
OGDH 4967 RUVBL1 8607 pp -- int.I2D: YeastLow
RPA1 6117 RUVBL2 10856 pp -- int.I2D: YeastLow
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow
ACTB 60 PSMB2 5690 pp -- int.I2D: BioGrid_Yeast
HSPD1 3329 PHB2 11331 pp -- int.I2D: IntAct_Yeast
RBX1 9978 PPIE 10450 pd <> reg.ITFP.txt: no annot
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
HSPD1 3329 RPA1 6117 pp -- int.I2D: YeastLow, IntAct_Yeast
PSMA1 5682 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Yeast, YeastHigh, BioGrid_Yeast
PPP2R1A 5518 PSMA3 5684 pp -- int.I2D: YeastLow, IntAct_Mouse
ACO2 50 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 VARS 7407 pp -- int.I2D: IntAct_Yeast
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
HSPD1 3329 PPP2R2C 5522 pp -- int.I2D: BioGrid
PPP2R1A 5518 RUVBL1 8607 pp -- int.I2D: YeastLow
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastMedium
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
TUBG1 7283 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PSMA3 5684 pp -- int.I2D: BioGrid, BioGrid_Yeast
RUVBL1 8607 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
RUVBL1 8607 RUVBL2 10856 pp -- int.Proteinpedia: Mass spectrometry;
int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid, BioGrid_Mouse, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct, IntAct_Fly, IntAct_Worm, IntAct_Yeast, INTEROLOG, MINT_Worm, MINT_Yeast, BCI, BioGrid_Fly, BIND_Fly, BIND_Worm, FlyHigh, INNATEDB, Krogan_Core, MIPS, YeastHigh, Yu_GoldStd;
int.Ravasi: -;
int.HPRD: in vitro, in vivo, yeast 2-hybrid;
int.DIP: MI:0915(physical association)
RPSA 3921 PHB2 11331 pp -- int.I2D: IntAct_Yeast
OGDH 4967 RB1 5925 pd < reg.ITFP.txt: no annot
EEF2 1938 PSMA3 5684 pp -- int.I2D: BioGrid
PSMA1 5682 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMA1 5682 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, BioGrid, YeastMedium
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
MTHFD1 4522 PRMT3 10196 pd < reg.ITFP.txt: no annot
EEF2 1938 RPA1 6117 pp -- int.I2D: YeastLow, Krogan_NonCore
PPP2R1A 5518 PSMB2 5690 pp -- int.I2D: IntAct_Mouse
ACTB 60 PPP2R1A 5518 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
EEF2 1938 PSMD3 5709 pp -- int.I2D: Krogan_NonCore
OGDH 4967 PGD 5226 pp -- int.I2D: YeastLow
PSMD1 5707 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMD1 5707 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, Krogan_Core, MINT_Yeast
PSMA1 5682 RPA1 6117 pd < reg.ITFP.txt: no annot
PSMB7 5695 RBX1 9978 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL2 10856 pp -- int.I2D: YeastLow
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
HNRNPC 3183 RUVBL1 8607 pd < reg.ITFP.txt: no annot
PSMD3 5709 RUVBL2 10856 pp -- int.I2D: YeastLow
VARS 7407 POLE4 56655 pd <> reg.ITFP.txt: no annot
PSMA2 5683 PSMB3 5691 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, INTEROLOG, Krogan_Core, MINT_Yeast, YeastHigh, Yu_GoldStd
PSMD3 5709 TUBG1 7283 pd > reg.ITFP.txt: no annot
PPP2R1A 5518 PSMB7 5695 pp -- int.I2D: IntAct_Mouse
PSMD11 5717 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BioGrid, IntAct, INTEROLOG
EIF4A1 1973 PPP2R1A 5518 pp -- int.Intact: MI:0914(association);
int.I2D: IntAct
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RB1 5925 pd < reg.ITFP.txt: no annot
HSPD1 3329 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
VARS 7407 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
HNRNPC 3183 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA2 5683 POLE4 56655 pd < reg.ITFP.txt: no annot
VARS 7407 RUVBL1 8607 pd <> reg.ITFP.txt: no annot
EEF2 1938 PPP2R1A 5518 pp -- int.Intact: MI:0914(association);
int.I2D: YeastLow, BioGrid, HPRD, IntAct;
int.HPRD: in vivo
PSMA3 5684 PSMD1 5707 pp -- int.I2D: BioGrid, BioGrid_Yeast
EEF2 1938 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMA3 5684 EFTUD2 9343 pp -- int.I2D: BioGrid
PSMB2 5690 RUVBL2 10856 pd < reg.ITFP.txt: no annot
HSPD1 3329 PSMA3 5684 pp -- int.I2D: BioGrid
OGDH 4967 PSMD14 10213 pp -- int.I2D: YeastLow
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
PSMB7 5695 POLE4 56655 pd < reg.ITFP.txt: no annot
PSMA3 5684 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast, IntAct_Mouse, MINT_Yeast, YeastLow, Krogan_Core
MTHFD1 4522 RUVBL1 8607 pd < reg.ITFP.txt: no annot
MTHFD1 4522 VARS 7407 pd < reg.ITFP.txt: no annot
MTHFD1 4522 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast, YeastLow, IntAct
PPP2R1A 5518 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMA3 5684 RUVBL1 8607 pp -- int.I2D: BioGrid
PSMB7 5695 PSMD14 10213 pd < reg.ITFP.txt: no annot
PSMB7 5695 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
TUBG1 7283 RUVBL1 8607 pd < reg.ITFP.txt: no annot
POLR2F 5435 RUVBL2 10856 pd < reg.ITFP.txt: no annot
PSMB3 5691 PSMB7 5695 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid_Yeast, BIND_Yeast, IntAct, IntAct_Yeast, YeastHigh, HPRD, Krogan_Core, MINT_Yeast, MIPS;
int.HPRD: yeast 2-hybrid
PSMB2 5690 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
MTHFD1 4522 RPA1 6117 pd < reg.ITFP.txt: no annot
RUVBL1 8607 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMD3 5709 VARS 7407 pd <> reg.ITFP.txt: no annot
PGD 5226 PPP2R1A 5518 pp -- int.I2D: YeastLow
PSMB7 5695 PSMD1 5707 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct
PSMA1 5682 PSMA3 5684 pp -- int.Intact: MI:0914(association), MI:0915(physical association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, CE_DATA, HPRD, IntAct, IntAct_Fly, IntAct_Mouse, IntAct_Worm, IntAct_Yeast, MINT_Worm, BioGrid, BioGrid_Fly, BIND_Fly, BIND_Yeast, FlyHigh, Krogan_Core, MINT_Fly, MINT_Yeast, YeastHigh, Yu_GoldStd;
int.HPRD: in vitro
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMD11 5717 TUBG1 7283 pd > reg.ITFP.txt: no annot
PSMA2 5683 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPSA 3921 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PSMA1 5682 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMB3 5691 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, INTEROLOG, MINT, Yu_GoldStd, BCI, BioGrid_Yeast, BIND_Yeast, HPRD, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
MTHFD1 4522 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
OGDH 4967 PSMD3 5709 pp -- int.I2D: YeastLow
PSMD11 5717 EFTUD2 9343 pd > reg.ITFP.txt: no annot
ACO2 50 PGD 5226 pp -- int.I2D: YeastLow
PSMD11 5717 RUVBL2 10856 pp -- int.I2D: YeastLow
OGDH 4967 PSMD11 5717 pp -- int.I2D: YeastLow
RPA1 6117 RPA2 6118 pp -- int.Intact: MI:0407(direct interaction), MI:0915(physical association);
int.I2D: HPRD, BCI, BioGrid, BIND, IntAct;
int.Transfac: -;
int.HPRD: in vitro, in vivo
PSMB3 5691 POLE4 56655 pd < reg.ITFP.txt: no annot
VARS 7407 RUVBL2 10856 pd <> reg.ITFP.txt: no annot
HSPD1 3329 PPP2R1A 5518 pp -- int.Intact: MI:0914(association);
int.I2D: HPRD, IntAct;
int.HPRD: in vivo
PSMB7 5695 PPIE 10450 pd < reg.ITFP.txt: no annot
EEF2 1938 RUVBL2 10856 pp -- int.I2D: YeastLow, BioGrid_Yeast, IntAct_Yeast
PSMD1 5707 RUVBL2 10856 pp -- int.I2D: IntAct_Yeast
ACO2 50 RUVBL1 8607 pp -- int.I2D: YeastLow
PSMA3 5684 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
HSPD1 3329 RPSA 3921 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
PPP2R1A 5518 PSMA2 5683 pp -- int.I2D: IntAct_Mouse
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
RB1 5925 TFRC 7037 pd > reg.ITFP.txt: no annot
PSMA3 5684 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
HSPD1 3329 OGDH 4967 pp -- int.I2D: YeastLow
PSMB2 5690 PSMD11 5717 pd < reg.ITFP.txt: no annot
PSMB2 5690 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB2 5690 VARS 7407 pd < reg.ITFP.txt: no annot
RPSA 3921 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA1 6117 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PPP2R1A 5518 PPP2R2C 5522 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid, IntAct
PSMD14 10213 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMB3 5691 PSMD11 5717 pp -- int.I2D: YeastLow
PSMD3 5709 PSMD14 10213 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid, BioGrid_Yeast, IntAct, IntAct_Yeast, INTEROLOG, MINT_Yeast, Krogan_Core, YeastHigh
RB1 5925 PPIE 10450 pd > reg.pazar.txt: no annot
PSMB7 5695 RPA1 6117 pd < reg.ITFP.txt: no annot
ACTB 60 RUVBL2 10856 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, YeastLow, BioGrid
PSMA2 5683 PSMA3 5684 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, IntAct_Fly, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, BIND_Yeast, HPRD;
int.HPRD: yeast 2-hybrid
PSMA3 5684 PSMB3 5691 pp -- int.I2D: BioGrid_Yeast, IntAct_Fly, IntAct_Yeast, YeastHigh
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
POLR2F 5435 VARS 7407 pd < reg.ITFP.txt: no annot
ACTB 60 PHB2 11331 pp -- int.I2D: IntAct_Yeast
RUVBL2 10856 PHB2 11331 pd > reg.ITFP.txt: no annot
RUVBL2 10856 PHB2 11331 pp -- int.I2D: IntAct_Yeast
ACTB 60 PSMD14 10213 pp -- int.I2D: BioGrid_Yeast
PSMB2 5690 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMB2 5690 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct, INTEROLOG, MINT_Yeast, YeastHigh, IntAct_Yeast, Krogan_Core

Related GO terms (482)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0000082G1/S transition of mitotic cell cycle8.74e-181.43e-135.2181333150
GO:0006521regulation of cellular amino acid metabolic process1.24e-172.02e-136.425102150
GO:0000502proteasome complex6.21e-171.01e-126.210102258
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.11e-163.44e-126.046102465
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.11e-163.44e-126.046102265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle4.63e-167.56e-125.939102470
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent7.22e-161.18e-115.879102373
GO:0016032viral process8.05e-161.31e-113.7571755540
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle8.34e-161.36e-115.859102474
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.27e-152.07e-115.802102377
GO:0010467gene expression1.33e-152.17e-113.5311858669
GO:0016071mRNA metabolic process1.63e-152.66e-114.6461334223
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.66e-152.71e-115.765102579
GO:0000278mitotic cell cycle4.58e-157.48e-114.0171552398
GO:0016070RNA metabolic process6.16e-151.01e-104.4991334247
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.02e-141.66e-105.514102394
GO:0005654nucleoplasm3.03e-144.95e-102.97220831095
GO:0000209protein polyubiquitination8.86e-141.45e-095.2101021116
GO:0034641cellular nitrogen compound metabolic process1.67e-132.72e-094.7381125177
GO:0042981regulation of apoptotic process1.29e-122.10e-084.8301026151
GO:0005839proteasome core complex1.92e-123.13e-087.16261118
GO:0004298threonine-type endopeptidase activity3.98e-126.50e-087.01061120
GO:0005829cytosol4.70e-127.67e-082.067251252562
GO:0070062extracellular vesicular exosome3.11e-115.07e-072.03524982516
GO:0043066negative regulation of apoptotic process2.55e-094.16e-053.4481130433
GO:0006915apoptotic process4.45e-087.26e-043.0491134571
GO:0022624proteasome accessory complex5.82e-089.49e-046.6594917
GO:0044281small molecule metabolic process7.74e-081.26e-032.31515571295
GO:0016020membrane6.14e-071.00e-021.97716801746
GO:0019773proteasome core complex, alpha-subunit complex6.47e-071.06e-027.331358
GO:0005838proteasome regulatory particle2.52e-064.12e-026.7473712
GO:0005634nucleus4.14e-066.75e-021.153251314828
GO:0035267NuA4 histone acetyltransferase complex4.16e-066.80e-026.5243414
GO:0005515protein binding6.36e-061.04e-010.973281726127
GO:0006281DNA repair3.03e-054.94e-013.287622264
GO:0000730DNA recombinase assembly5.26e-058.58e-017.425235
GO:0030529ribonucleoprotein complex1.39e-041.00e+003.91448114
GO:0000812Swr1 complex1.47e-041.00e+006.747238
GO:0006283transcription-coupled nucleotide-excision repair1.65e-041.00e+004.8083846
GO:0040008regulation of growth2.24e-041.00e+004.6593351
GO:0003684damaged DNA binding2.24e-041.00e+004.65931151
GO:0003725double-stranded RNA binding2.66e-041.00e+004.5773654
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding2.66e-041.00e+004.5773554
GO:0000724double-strand break repair via homologous recombination3.12e-041.00e+004.4993657
GO:0043968histone H2A acetylation3.43e-041.00e+006.1622312
GO:0005662DNA replication factor A complex4.05e-041.00e+006.0462313
GO:0030234enzyme regulator activity4.05e-041.00e+006.0462313
GO:0031011Ino80 complex4.72e-041.00e+005.9392314
GO:0006310DNA recombination5.03e-041.00e+004.2653467
GO:0006289nucleotide-excision repair5.49e-041.00e+004.22331269
GO:0003697single-stranded DNA binding5.49e-041.00e+004.2233969
GO:0000398mRNA splicing, via spliceosome5.69e-041.00e+003.380412165
GO:0042176regulation of protein catabolic process6.21e-041.00e+005.7472316
GO:0071013catalytic step 2 spliceosome8.15e-041.00e+004.0283779
GO:0003678DNA helicase activity8.80e-041.00e+005.4992319
GO:0008601protein phosphatase type 2A regulator activity9.77e-041.00e+005.4252320
GO:0006298mismatch repair9.77e-041.00e+005.4252620
GO:0000159protein phosphatase type 2A complex9.77e-041.00e+005.4252220
GO:0000718nucleotide-excision repair, DNA damage removal1.08e-031.00e+005.3542521
GO:0005730nucleolus1.18e-031.00e+001.48811701684
GO:0006297nucleotide-excision repair, DNA gap filling1.18e-031.00e+005.2872522
GO:0032201telomere maintenance via semi-conservative replication1.18e-031.00e+005.2872722
GO:0016363nuclear matrix1.27e-031.00e+003.80831192
GO:0016605PML body1.27e-031.00e+003.8083592
GO:0043044ATP-dependent chromatin remodeling1.29e-031.00e+005.2232423
GO:0005844polysome1.53e-031.00e+005.1032425
GO:0000722telomere maintenance via recombination1.66e-031.00e+005.0462726
GO:0071339MLL1 complex1.79e-031.00e+004.9922327
GO:0043967histone H4 acetylation1.92e-031.00e+004.9392328
GO:0031492nucleosomal DNA binding1.92e-031.00e+004.9392428
GO:0008380RNA splicing2.01e-031.00e+002.889413232
GO:0006099tricarboxylic acid cycle2.06e-031.00e+004.8892329
GO:0002842positive regulation of T cell mediated immune response to tumor cell2.33e-031.00e+008.747111
GO:0048291isotype switching to IgG isotypes2.33e-031.00e+008.747111
GO:0034602oxoglutarate dehydrogenase (NAD+) activity2.33e-031.00e+008.747111
GO:0008541proteasome regulatory particle, lid subcomplex2.33e-031.00e+008.747111
GO:0090230regulation of centromere complex assembly2.33e-031.00e+008.747111
GO:0070262peptidyl-serine dephosphorylation2.33e-031.00e+008.747111
GO:0004632phosphopantothenate--cysteine ligase activity2.33e-031.00e+008.747111
GO:0019521D-gluconate metabolic process2.33e-031.00e+008.747111
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity2.33e-031.00e+008.747111
GO:0002368B cell cytokine production2.33e-031.00e+008.747111
GO:0006271DNA strand elongation involved in DNA replication2.35e-031.00e+004.7922931
GO:0005739mitochondrion2.41e-031.00e+001.7168241046
GO:0006325chromatin organization2.91e-031.00e+003.38934123
GO:0044822poly(A) RNA binding2.91e-031.00e+001.6728501078
GO:0006284base-excision repair3.70e-031.00e+004.4612739
GO:0032508DNA duplex unwinding4.29e-031.00e+004.3542442
GO:0016887ATPase activity4.53e-031.00e+003.16237144
GO:0004832valine-tRNA ligase activity4.65e-031.00e+007.747112
GO:0045252oxoglutarate dehydrogenase complex4.65e-031.00e+007.747122
GO:00515383 iron, 4 sulfur cluster binding4.65e-031.00e+007.747112
GO:0003994aconitate hydratase activity4.65e-031.00e+007.747112
GO:0097286iron ion import4.65e-031.00e+007.747112
GO:0006407rRNA export from nucleus4.65e-031.00e+007.747112
GO:0006438valyl-tRNA aminoacylation4.65e-031.00e+007.747112
GO:0061034olfactory bulb mitral cell layer development4.65e-031.00e+007.747112
GO:0000105histidine biosynthetic process4.65e-031.00e+007.747112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.65e-031.00e+007.747112
GO:0004998transferrin receptor activity4.65e-031.00e+007.747112
GO:0019322pentose biosynthetic process4.65e-031.00e+007.747112
GO:0031134sister chromatid biorientation4.65e-031.00e+007.747112
GO:0005055laminin receptor activity4.65e-031.00e+007.747112
GO:0007070negative regulation of transcription from RNA polymerase II promoter during mitosis4.65e-031.00e+007.747122
GO:0006457protein folding4.98e-031.00e+003.11238149
GO:0043234protein complex5.05e-031.00e+002.518417300
GO:0006091generation of precursor metabolites and energy6.26e-031.00e+004.0742351
GO:0005905coated pit6.26e-031.00e+004.0742251
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity6.97e-031.00e+007.162113
GO:0022028tangential migration from the subventricular zone to the olfactory bulb6.97e-031.00e+007.162113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity6.97e-031.00e+007.162113
GO:0071459protein localization to chromosome, centromeric region6.97e-031.00e+007.162113
GO:0071899negative regulation of estrogen receptor binding6.97e-031.00e+007.162113
GO:0006458'de novo' protein folding6.97e-031.00e+007.162113
GO:0071733transcriptional activation by promoter-enhancer looping6.97e-031.00e+007.162113
GO:0009051pentose-phosphate shunt, oxidative branch6.97e-031.00e+007.162113
GO:0030135coated vesicle6.97e-031.00e+007.162113
GO:0071930negative regulation of transcription involved in G1/S transition of mitotic cell cycle6.97e-031.00e+007.162113
GO:0051087chaperone binding8.31e-031.00e+003.8642659
GO:0000723telomere maintenance8.31e-031.00e+003.8642859
GO:0031625ubiquitin protein ligase binding8.38e-031.00e+002.840313180
GO:0006302double-strand break repair9.14e-031.00e+003.7922862
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)9.28e-031.00e+006.747114
GO:0000212meiotic spindle organization9.28e-031.00e+006.747114
GO:003068690S preribosome9.28e-031.00e+006.747114
GO:0071922regulation of cohesin localization to chromatin9.28e-031.00e+006.747114
GO:0019788NEDD8 ligase activity9.28e-031.00e+006.747114
GO:0016274protein-arginine N-methyltransferase activity9.28e-031.00e+006.747114
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activity9.28e-031.00e+006.747114
GO:0004329formate-tetrahydrofolate ligase activity9.28e-031.00e+006.747114
GO:0043141ATP-dependent 5'-3' DNA helicase activity9.28e-031.00e+006.747114
GO:0034969histone arginine methylation9.28e-031.00e+006.747114
GO:0006104succinyl-CoA metabolic process9.28e-031.00e+006.747114
GO:0009396folic acid-containing compound biosynthetic process9.28e-031.00e+006.747114
GO:0004477methenyltetrahydrofolate cyclohydrolase activity9.28e-031.00e+006.747114
GO:0031467Cul7-RING ubiquitin ligase complex9.28e-031.00e+006.747114
GO:0043550regulation of lipid kinase activity9.28e-031.00e+006.747114
GO:0035189Rb-E2F complex9.28e-031.00e+006.747114
GO:0034349glial cell apoptotic process9.28e-031.00e+006.747114
GO:0034088maintenance of mitotic sister chromatid cohesion9.28e-031.00e+006.747114
GO:0006338chromatin remodeling1.09e-021.00e+003.6592468
GO:0003924GTPase activity1.16e-021.00e+002.66639203
GO:0031465Cul4B-RING E3 ubiquitin ligase complex1.16e-021.00e+006.425125
GO:0019932second-messenger-mediated signaling1.16e-021.00e+006.425115
GO:0009086methionine biosynthetic process1.16e-021.00e+006.425115
GO:0042518negative regulation of tyrosine phosphorylation of Stat3 protein1.16e-021.00e+006.425115
GO:2000001regulation of DNA damage checkpoint1.16e-021.00e+006.425115
GO:0008622epsilon DNA polymerase complex1.16e-021.00e+006.425115
GO:0031461cullin-RING ubiquitin ligase complex1.16e-021.00e+006.425115
GO:0071169establishment of protein localization to chromatin1.16e-021.00e+006.425115
GO:0043248proteasome assembly1.16e-021.00e+006.425115
GO:0046696lipopolysaccharide receptor complex1.16e-021.00e+006.425115
GO:0048667cell morphogenesis involved in neuron differentiation1.16e-021.00e+006.425115
GO:0006102isocitrate metabolic process1.16e-021.00e+006.425115
GO:0030891VCB complex1.16e-021.00e+006.425125
GO:0033600negative regulation of mammary gland epithelial cell proliferation1.16e-021.00e+006.425115
GO:0005827polar microtubule1.16e-021.00e+006.425115
GO:0006734NADH metabolic process1.16e-021.00e+006.425115
GO:0061133endopeptidase activator activity1.16e-021.00e+006.425115
GO:0030976thiamine pyrophosphate binding1.16e-021.00e+006.425115
GO:0006767water-soluble vitamin metabolic process1.32e-021.00e+003.5182375
GO:0043353enucleate erythrocyte differentiation1.39e-021.00e+006.162116
GO:0009108coenzyme biosynthetic process1.39e-021.00e+006.162116
GO:0003688DNA replication origin binding1.39e-021.00e+006.162116
GO:0045842positive regulation of mitotic metaphase/anaphase transition1.39e-021.00e+006.162116
GO:0060744mammary gland branching involved in thelarche1.39e-021.00e+006.162116
GO:0006101citrate metabolic process1.39e-021.00e+006.162116
GO:0021860pyramidal neuron development1.39e-021.00e+006.162116
GO:0031466Cul5-RING ubiquitin ligase complex1.39e-021.00e+006.162116
GO:0021695cerebellar cortex development1.39e-021.00e+006.162116
GO:0030957Tat protein binding1.39e-021.00e+006.162146
GO:0019907cyclin-dependent protein kinase activating kinase holoenzyme complex1.39e-021.00e+006.162116
GO:0008469histone-arginine N-methyltransferase activity1.39e-021.00e+006.162116
GO:0060762regulation of branching involved in mammary gland duct morphogenesis1.39e-021.00e+006.162116
GO:0006766vitamin metabolic process1.42e-021.00e+003.4612378
GO:0006184GTP catabolic process1.44e-021.00e+002.55039220
GO:0005681spliceosomal complex1.60e-021.00e+003.3712383
GO:0010950positive regulation of endopeptidase activity1.62e-021.00e+005.939117
GO:0000028ribosomal small subunit assembly1.62e-021.00e+005.939117
GO:0002161aminoacyl-tRNA editing activity1.62e-021.00e+005.939127
GO:0035242protein-arginine omega-N asymmetric methyltransferase activity1.62e-021.00e+005.939117
GO:0031462Cul2-RING ubiquitin ligase complex1.62e-021.00e+005.939127
GO:0035999tetrahydrofolate interconversion1.62e-021.00e+005.939117
GO:0072341modified amino acid binding1.62e-021.00e+005.939117
GO:0000930gamma-tubulin complex1.62e-021.00e+005.939117
GO:0019919peptidyl-arginine methylation, to asymmetrical-dimethyl arginine1.62e-021.00e+005.939117
GO:0016018cyclosporin A binding1.62e-021.00e+005.939117
GO:0005759mitochondrial matrix1.68e-021.00e+002.467312233
GO:0006412translation1.72e-021.00e+002.455315235
GO:0031464Cul4A-RING E3 ubiquitin ligase complex1.85e-021.00e+005.747128
GO:0001055RNA polymerase II activity1.85e-021.00e+005.747138
GO:0000339RNA cap binding1.85e-021.00e+005.747118
GO:0070688MLL5-L complex1.85e-021.00e+005.747118
GO:0006554lysine catabolic process1.85e-021.00e+005.747128
GO:0045116protein neddylation1.85e-021.00e+005.747128
GO:0000800lateral element1.85e-021.00e+005.747118
GO:0006164purine nucleotide biosynthetic process1.85e-021.00e+005.747128
GO:0006414translational elongation1.98e-021.00e+003.20721193
GO:0005200structural constituent of cytoskeleton1.98e-021.00e+003.2072793
GO:0051082unfolded protein binding2.06e-021.00e+003.1772695
GO:0016281eukaryotic translation initiation factor 4F complex2.08e-021.00e+005.577119
GO:0015937coenzyme A biosynthetic process2.08e-021.00e+005.577119
GO:0008494translation activator activity2.08e-021.00e+005.577119
GO:0097284hepatocyte apoptotic process2.08e-021.00e+005.577129
GO:0000075cell cycle checkpoint2.08e-021.00e+005.577129
GO:0070628proteasome binding2.30e-021.00e+005.4251110
GO:0046655folic acid metabolic process2.30e-021.00e+005.4251110
GO:0006450regulation of translational fidelity2.30e-021.00e+005.4251210
GO:0043032positive regulation of macrophage activation2.30e-021.00e+005.4251110
GO:0033147negative regulation of intracellular estrogen receptor signaling pathway2.30e-021.00e+005.4251110
GO:0007084mitotic nuclear envelope reassembly2.30e-021.00e+005.4251110
GO:0015939pantothenate metabolic process2.30e-021.00e+005.4251110
GO:0051604protein maturation2.30e-021.00e+005.4251110
GO:0021756striatum development2.30e-021.00e+005.4251110
GO:0006098pentose-phosphate shunt2.53e-021.00e+005.2871311
GO:0032727positive regulation of interferon-alpha production2.53e-021.00e+005.2871111
GO:0010569regulation of double-strand break repair via homologous recombination2.53e-021.00e+005.2871111
GO:0031571mitotic G1 DNA damage checkpoint2.53e-021.00e+005.2871311
GO:0042551neuron maturation2.53e-021.00e+005.2871211
GO:0001054RNA polymerase I activity2.53e-021.00e+005.2871311
GO:0045651positive regulation of macrophage differentiation2.53e-021.00e+005.2871211
GO:0045120pronucleus2.53e-021.00e+005.2871111
GO:0042802identical protein binding2.66e-021.00e+001.807418491
GO:0044267cellular protein metabolic process2.73e-021.00e+001.795424495
GO:0061136regulation of proteasomal protein catabolic process2.76e-021.00e+005.1621112
GO:00709353'-UTR-mediated mRNA stabilization2.76e-021.00e+005.1621212
GO:0051146striated muscle cell differentiation2.76e-021.00e+005.1621112
GO:0005736DNA-directed RNA polymerase I complex2.76e-021.00e+005.1621312
GO:0006275regulation of DNA replication2.76e-021.00e+005.1621212
GO:0021794thalamus development2.76e-021.00e+005.1621112
GO:0030111regulation of Wnt signaling pathway2.76e-021.00e+005.1621112
GO:0015630microtubule cytoskeleton2.79e-021.00e+002.93925112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay2.89e-021.00e+002.914210114
GO:0072562blood microparticle2.98e-021.00e+002.88924116
GO:0045780positive regulation of bone resorption2.99e-021.00e+005.0461113
GO:0001530lipopolysaccharide binding2.99e-021.00e+005.0461213
GO:0008266poly(U) RNA binding2.99e-021.00e+005.0461113
GO:0051131chaperone-mediated protein complex assembly2.99e-021.00e+005.0461113
GO:0044237cellular metabolic process3.08e-021.00e+002.86423118
GO:0007020microtubule nucleation3.21e-021.00e+004.9391114
GO:0006200ATP catabolic process3.31e-021.00e+002.088314303
GO:0006260DNA replication3.42e-021.00e+002.781212125
GO:0006672ceramide metabolic process3.44e-021.00e+004.8401115
GO:0045445myoblast differentiation3.44e-021.00e+004.8401215
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand3.44e-021.00e+004.8401215
GO:0035066positive regulation of histone acetylation3.44e-021.00e+004.8401115
GO:0042026protein refolding3.44e-021.00e+004.8401215
GO:0005671Ada2/Gcn5/Ada3 transcription activator complex3.44e-021.00e+004.8401115
GO:0016514SWI/SNF complex3.44e-021.00e+004.8401315
GO:0006261DNA-dependent DNA replication3.44e-021.00e+004.8401215
GO:0060749mammary gland alveolus development3.44e-021.00e+004.8401115
GO:0005524ATP binding3.46e-021.00e+001.1517461354
GO:0006511ubiquitin-dependent protein catabolic process3.52e-021.00e+002.75825127
GO:0005665DNA-directed RNA polymerase II, core complex3.66e-021.00e+004.7471416
GO:0050998nitric-oxide synthase binding3.66e-021.00e+004.7471116
GO:0001673male germ cell nucleus3.66e-021.00e+004.7471116
GO:00061032-oxoglutarate metabolic process3.66e-021.00e+004.7471116
GO:0001056RNA polymerase III activity3.66e-021.00e+004.7471316
GO:0006413translational initiation3.72e-021.00e+002.713212131
GO:0000790nuclear chromatin3.83e-021.00e+002.69127133
GO:0010243response to organonitrogen compound3.89e-021.00e+004.6591217
GO:0005666DNA-directed RNA polymerase III complex3.89e-021.00e+004.6591317
GO:0003746translation elongation factor activity3.89e-021.00e+004.6591317
GO:0045070positive regulation of viral genome replication3.89e-021.00e+004.6591117
GO:0050870positive regulation of T cell activation3.89e-021.00e+004.6591117
GO:0007126meiotic nuclear division3.89e-021.00e+004.6591117
GO:0000086G2/M transition of mitotic cell cycle4.04e-021.00e+002.64827137
GO:0005525GTP binding4.04e-021.00e+001.974311328
GO:0070536protein K63-linked deubiquitination4.11e-021.00e+004.5771118
GO:0006386termination of RNA polymerase III transcription4.11e-021.00e+004.5771318
GO:0071392cellular response to estradiol stimulus4.11e-021.00e+004.5771118
GO:0031122cytoplasmic microtubule organization4.11e-021.00e+004.5771218
GO:0035861site of double-strand break4.11e-021.00e+004.5771118
GO:0006385transcription elongation from RNA polymerase III promoter4.11e-021.00e+004.5771318
GO:0006303double-strand break repair via nonhomologous end joining4.11e-021.00e+004.5771318
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process4.33e-021.00e+004.4991119
GO:0048863stem cell differentiation4.33e-021.00e+004.4991119
GO:0032733positive regulation of interleukin-10 production4.33e-021.00e+004.4991119
GO:2000134negative regulation of G1/S transition of mitotic cell cycle4.56e-021.00e+004.4251220
GO:0048873homeostasis of number of cells within a tissue4.56e-021.00e+004.4251120
GO:0005719nuclear euchromatin4.56e-021.00e+004.4251220
GO:0045595regulation of cell differentiation4.78e-021.00e+004.3541121
GO:0003723RNA binding4.92e-021.00e+001.860319355
GO:0030316osteoclast differentiation5.00e-021.00e+004.2871222
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle5.00e-021.00e+004.2871322
GO:0030863cortical cytoskeleton5.00e-021.00e+004.2871122
GO:0036464cytoplasmic ribonucleoprotein granule5.00e-021.00e+004.2871422
GO:0031463Cul3-RING ubiquitin ligase complex5.22e-021.00e+004.2231223
GO:0043236laminin binding5.22e-021.00e+004.2231123
GO:0006513protein monoubiquitination5.22e-021.00e+004.2231123
GO:0045879negative regulation of smoothened signaling pathway5.22e-021.00e+004.2231123
GO:0008135translation factor activity, nucleic acid binding5.44e-021.00e+004.1621424
GO:0000794condensed nuclear chromosome5.44e-021.00e+004.1621224
GO:0042100B cell proliferation5.67e-021.00e+004.1031125
GO:0000289nuclear-transcribed mRNA poly(A) tail shortening5.67e-021.00e+004.1031125
GO:0042113B cell activation5.67e-021.00e+004.1031225
GO:0032735positive regulation of interleukin-12 production5.67e-021.00e+004.1031125
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding5.82e-021.00e+002.35425168
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia5.88e-021.00e+004.0461226
GO:0006730one-carbon metabolic process5.88e-021.00e+004.0461126
GO:0004003ATP-dependent DNA helicase activity6.10e-021.00e+003.9921327
GO:0000188inactivation of MAPK activity6.10e-021.00e+003.9921127
GO:0034080CENP-A containing nucleosome assembly6.10e-021.00e+003.9921227
GO:0030331estrogen receptor binding6.10e-021.00e+003.9921227
GO:0048565digestive tract development6.10e-021.00e+003.9921127
GO:0003823antigen binding6.32e-021.00e+003.9391128
GO:0010033response to organic substance6.32e-021.00e+003.9391228
GO:0043022ribosome binding6.32e-021.00e+003.9391328
GO:0019894kinesin binding6.32e-021.00e+003.9391128
GO:0019005SCF ubiquitin ligase complex6.54e-021.00e+003.8891129
GO:0003730mRNA 3'-UTR binding6.54e-021.00e+003.8891229
GO:0003887DNA-directed DNA polymerase activity6.54e-021.00e+003.8891329
GO:0071897DNA biosynthetic process6.54e-021.00e+003.8891229
GO:00063707-methylguanosine mRNA capping6.76e-021.00e+003.8401430
GO:0006360transcription from RNA polymerase I promoter6.76e-021.00e+003.8401430
GO:0007346regulation of mitotic cell cycle6.76e-021.00e+003.8401330
GO:0015629actin cytoskeleton6.76e-021.00e+002.23125183
GO:0007093mitotic cell cycle checkpoint6.98e-021.00e+003.7921231
GO:0050661NADP binding7.19e-021.00e+003.7471132
GO:0031397negative regulation of protein ubiquitination7.19e-021.00e+003.7471132
GO:0051219phosphoprotein binding7.19e-021.00e+003.7471332
GO:0034644cellular response to UV7.19e-021.00e+003.7471532
GO:0033572transferrin transport7.19e-021.00e+003.7471632
GO:0031072heat shock protein binding7.41e-021.00e+003.7021233
GO:0000413protein peptidyl-prolyl isomerization7.63e-021.00e+003.6591134
GO:0003755peptidyl-prolyl cis-trans isomerase activity7.63e-021.00e+003.6591134
GO:0034332adherens junction organization8.06e-021.00e+003.5771136
GO:0004221ubiquitin thiolesterase activity8.06e-021.00e+003.5771236
GO:0051402neuron apoptotic process8.06e-021.00e+003.5771236
GO:0001895retina homeostasis8.06e-021.00e+003.5771136
GO:0032755positive regulation of interleukin-6 production8.06e-021.00e+003.5771236
GO:0001102RNA polymerase II activating transcription factor binding8.27e-021.00e+003.5371437
GO:0051084'de novo' posttranslational protein folding8.27e-021.00e+003.5371437
GO:00515394 iron, 4 sulfur cluster binding8.27e-021.00e+003.5371337
GO:0070527platelet aggregation8.49e-021.00e+003.4991238
GO:0050681androgen receptor binding8.49e-021.00e+003.4991438
GO:0021766hippocampus development8.70e-021.00e+003.4611439
GO:0006383transcription from RNA polymerase III promoter8.70e-021.00e+003.4611339
GO:0008026ATP-dependent helicase activity8.70e-021.00e+003.4611339
GO:0031490chromatin DNA binding8.70e-021.00e+003.4611239
GO:0006096glycolytic process8.70e-021.00e+003.4611439
GO:0032729positive regulation of interferon-gamma production8.70e-021.00e+003.4611239
GO:0022627cytosolic small ribosomal subunit8.70e-021.00e+003.4611339
GO:0000781chromosome, telomeric region8.91e-021.00e+003.4251240
GO:0030521androgen receptor signaling pathway9.13e-021.00e+003.3891241
GO:0006418tRNA aminoacylation for protein translation9.34e-021.00e+003.3541542
GO:0004722protein serine/threonine phosphatase activity9.34e-021.00e+003.3541142
GO:0035914skeletal muscle cell differentiation9.34e-021.00e+003.3541142
GO:0030155regulation of cell adhesion9.34e-021.00e+003.3541342
GO:0042110T cell activation9.55e-021.00e+003.3201343
GO:0014070response to organic cyclic compound9.55e-021.00e+003.3201343
GO:0000979RNA polymerase II core promoter sequence-specific DNA binding9.76e-021.00e+003.2871244
GO:0050434positive regulation of viral transcription9.76e-021.00e+003.2871544
GO:0015030Cajal body9.97e-021.00e+003.2551245
GO:0043966histone H3 acetylation9.97e-021.00e+003.2551245
GO:0021762substantia nigra development1.02e-011.00e+003.2231146
GO:0001047core promoter binding1.02e-011.00e+003.2231246
GO:0045727positive regulation of translation1.02e-011.00e+003.2231446
GO:0003743translation initiation factor activity1.08e-011.00e+003.1321449
GO:0031100organ regeneration1.10e-011.00e+003.1031450
GO:0006986response to unfolded protein1.12e-011.00e+003.0741251
GO:0000775chromosome, centromeric region1.14e-011.00e+003.0461252
GO:0008168methyltransferase activity1.14e-011.00e+003.0461152
GO:0000288nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay1.16e-011.00e+003.0191153
GO:0019900kinase binding1.18e-011.00e+002.9921154
GO:0050680negative regulation of epithelial cell proliferation1.18e-011.00e+002.9921154
GO:0000226microtubule cytoskeleton organization1.21e-011.00e+002.9651355
GO:0002039p53 binding1.21e-011.00e+002.9651755
GO:0000932cytoplasmic mRNA processing body1.23e-011.00e+002.9391356
GO:0004386helicase activity1.23e-011.00e+002.9391456
GO:0006879cellular iron ion homeostasis1.25e-011.00e+002.9141557
GO:0030097hemopoiesis1.27e-011.00e+002.8891358
GO:0002244hematopoietic progenitor cell differentiation1.27e-011.00e+002.8891158
GO:0008237metallopeptidase activity1.27e-011.00e+002.8891158
GO:0005840ribosome1.29e-011.00e+002.8641259
GO:0043433negative regulation of sequence-specific DNA binding transcription factor activity1.29e-011.00e+002.8641459
GO:0045216cell-cell junction organization1.29e-011.00e+002.8641259
GO:0031966mitochondrial membrane1.29e-011.00e+002.8641159
GO:0000166nucleotide binding1.32e-011.00e+001.65926272
GO:0032481positive regulation of type I interferon production1.33e-011.00e+002.8161661
GO:0019903protein phosphatase binding1.37e-011.00e+002.7691463
GO:0007059chromosome segregation1.39e-011.00e+002.7471364
GO:0006469negative regulation of protein kinase activity1.41e-011.00e+002.7241265
GO:0001558regulation of cell growth1.43e-011.00e+002.7021466
GO:0006368transcription elongation from RNA polymerase II promoter1.45e-011.00e+002.6801667
GO:0030141secretory granule1.45e-011.00e+002.6801267
GO:0050790regulation of catalytic activity1.49e-011.00e+002.6381369
GO:0034329cell junction assembly1.53e-011.00e+002.5971171
GO:0005743mitochondrial inner membrane1.54e-011.00e+001.51825300
GO:0055037recycling endosome1.57e-011.00e+002.5571273
GO:0003729mRNA binding1.57e-011.00e+002.5571473
GO:0000785chromatin1.57e-011.00e+002.5571573
GO:0007265Ras protein signal transduction1.61e-011.00e+002.5181375
GO:0031175neuron projection development1.61e-011.00e+002.5181175
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process1.63e-011.00e+002.4991376
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis1.65e-011.00e+002.4801577
GO:0006919activation of cysteine-type endopeptidase activity involved in apoptotic process1.65e-011.00e+002.4801677
GO:0006334nucleosome assembly1.69e-011.00e+002.4431479
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.71e-011.00e+002.4251280
GO:0019901protein kinase binding1.71e-011.00e+001.425221320
GO:0019083viral transcription1.72e-011.00e+002.4071881
GO:0043231intracellular membrane-bounded organelle1.81e-011.00e+001.37128332
GO:0047485protein N-terminus binding1.82e-011.00e+002.3201486
GO:0006898receptor-mediated endocytosis1.82e-011.00e+002.3201286
GO:0006415translational termination1.84e-011.00e+002.3041887
GO:0005813centrosome1.86e-011.00e+001.341212339
GO:0050821protein stabilization1.92e-011.00e+002.2391291
GO:0042470melanosome1.94e-011.00e+002.22311092
GO:0006928cellular component movement1.94e-011.00e+002.2231792
GO:0005737cytoplasm1.95e-011.00e+000.37412983976
GO:0001649osteoblast differentiation1.99e-011.00e+002.1771695
GO:0071456cellular response to hypoxia2.05e-011.00e+002.1321498
GO:0006470protein dephosphorylation2.07e-011.00e+002.1171199
GO:0006614SRP-dependent cotranslational protein targeting to membrane2.16e-011.00e+002.04618104
GO:0014069postsynaptic density2.20e-011.00e+002.01911106
GO:0016023cytoplasmic membrane-bounded vesicle2.21e-011.00e+002.00513107
GO:0005815microtubule organizing center2.27e-011.00e+001.96514110
GO:0042127regulation of cell proliferation2.29e-011.00e+001.95214111
GO:0006461protein complex assembly2.29e-011.00e+001.95216111
GO:0030308negative regulation of cell growth2.32e-011.00e+001.92616113
GO:0005819spindle2.34e-011.00e+001.91417114
GO:0019058viral life cycle2.36e-011.00e+001.901110115
GO:0046982protein heterodimerization activity2.38e-011.00e+001.106211399
GO:0007219Notch signaling pathway2.54e-011.00e+001.78114125
GO:0007050cell cycle arrest2.55e-011.00e+001.76917126
GO:0005506iron ion binding2.57e-011.00e+001.75813127
GO:0009986cell surface2.58e-011.00e+001.02529422
GO:0045892negative regulation of transcription, DNA-templated2.59e-011.00e+001.019214424
GO:0009615response to virus2.66e-011.00e+001.70216132
GO:0031982vesicle2.69e-011.00e+001.680110134
GO:0003735structural constituent of ribosome2.81e-011.00e+001.60718141
GO:0061024membrane organization2.90e-011.00e+001.55715146
GO:0010628positive regulation of gene expression2.95e-011.00e+001.52714149
GO:0005769early endosome3.09e-011.00e+001.44312158
GO:0055114oxidation-reduction process3.09e-011.00e+000.837211481
GO:0008543fibroblast growth factor receptor signaling pathway3.11e-011.00e+001.43414159
GO:0006397mRNA processing3.27e-011.00e+001.34613169
GO:0030424axon3.32e-011.00e+001.32013172
GO:0005768endosome3.35e-011.00e+001.30415174
GO:0016607nuclear speck3.36e-011.00e+001.29514175
GO:0009897external side of plasma membrane3.49e-011.00e+001.23114183
GO:0006367transcription initiation from RNA polymerase II promoter3.50e-011.00e+001.22318184
GO:0032403protein complex binding3.52e-011.00e+001.21517185
GO:0001701in utero embryonic development3.89e-011.00e+001.03216210
GO:0005622intracellular4.12e-011.00e+000.92615226
GO:0019221cytokine-mediated signaling pathway4.17e-011.00e+000.90113230
GO:0007067mitotic nuclear division4.19e-011.00e+000.895113231
GO:0005615extracellular space4.21e-011.00e+000.3513171010
GO:0045087innate immune response4.23e-011.00e+000.480220616
GO:0003713transcription coactivator activity4.29e-011.00e+000.846110239
GO:0008134transcription factor binding4.39e-011.00e+000.80418246
GO:0046872metal ion binding4.48e-011.00e+000.2304241465
GO:0005794Golgi apparatus4.50e-011.00e+000.402214650
GO:0004842ubiquitin-protein transferase activity4.52e-011.00e+000.74714256
GO:0005975carbohydrate metabolic process4.75e-011.00e+000.64815274
GO:0043065positive regulation of apoptotic process4.75e-011.00e+000.64818274
GO:0006357regulation of transcription from RNA polymerase II promoter4.76e-011.00e+000.64316275
GO:0007283spermatogenesis4.77e-011.00e+000.63816276
GO:0006355regulation of transcription, DNA-templated4.79e-011.00e+000.2233171104
GO:0019899enzyme binding4.92e-011.00e+000.577111288
GO:0016567protein ubiquitination5.05e-011.00e+000.52315299
GO:0006351transcription, DNA-templated5.11e-011.00e+000.1164251585
GO:0005856cytoskeleton5.19e-011.00e+000.46618311
GO:0007411axon guidance5.37e-011.00e+000.39319327
GO:0003682chromatin binding5.45e-011.00e+000.363112334
GO:0045944positive regulation of transcription from RNA polymerase II promoter5.70e-011.00e+000.083219811
GO:0043565sequence-specific DNA binding5.77e-011.00e+000.23514365
GO:0005925focal adhesion5.82e-011.00e+000.215118370
GO:0007155cell adhesion5.96e-011.00e+000.16218384
GO:0008284positive regulation of cell proliferation6.03e-011.00e+000.13218392
GO:0006366transcription from RNA polymerase II promoter6.34e-011.00e+000.015112425
GO:0007596blood coagulation6.66e-011.00e+00-0.111114464
GO:0045893positive regulation of transcription, DNA-templated6.84e-011.00e+00-0.181117487
GO:0055085transmembrane transport7.04e-011.00e+00-0.25918514
GO:0048471perinuclear region of cytoplasm7.10e-011.00e+00-0.284112523
GO:0003700sequence-specific DNA binding transcription factor activity8.32e-011.00e+00-0.800111748
GO:0003677DNA binding8.34e-011.00e+00-0.6532261351
GO:0007165signal transduction8.98e-011.00e+00-1.145117950
GO:0005887integral component of plasma membrane9.01e-011.00e+00-1.16217961
GO:0005576extracellular region9.20e-011.00e+00-1.288191049
GO:0008270zinc ion binding9.24e-011.00e+00-1.3131121067
GO:0005886plasma membrane9.72e-011.00e+00-1.1373382834