int-snw-51144

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.945 6.88e-16 2.00e-03 3.44e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-51144 subnetwork

Genes (14)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
RSL24D1 51187 361.3001.02059Yes-
PSMD1 5707 120.8361.057113Yes-
RUVBL1 8607 170.7201.013343Yes-
PIGK 10026 50.7180.99268Yes-
PSMA2 5683 601.0931.10689Yes-
RPL14 9045 421.2501.113143Yes-
RPL30 6156 40.7561.043164Yes-
PSMD11 5717 1211.0951.106183Yes-
ACTB 60 1671.1531.151587Yes-
ATP6V1B2 526 440.8811.076278--
CFL1 1072 120.6741.020203Yes-
[ HSD17B12 ] 51144 1-0.2180.94586--
RPSA 3921 1561.3271.151152Yes-
PGD 5226 751.2011.106138Yes-

Interactions (22)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
PSMD1 5707 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast
ATP6V1B2 526 RPSA 3921 pp -- int.I2D: IntAct_Yeast
ACTB 60 ATP6V1B2 526 pp -- int.I2D: BioGrid_Yeast
PSMA2 5683 PSMD1 5707 pp -- int.I2D: BioGrid_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
PIGK 10026 HSD17B12 51144 pp -- int.I2D: MINT_Yeast, BioGrid_Yeast
CFL1 1072 RSL24D1 51187 pp -- int.I2D: YeastLow
RPL30 6156 RPL14 9045 pp -- int.I2D: BioGrid_Yeast
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
CFL1 1072 HSD17B12 51144 pp -- int.I2D: BioGrid_Yeast, Krogan_Core, MINT_Yeast
RPL30 6156 HSD17B12 51144 pp -- int.I2D: IntAct_Yeast
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
ATP6V1B2 526 HSD17B12 51144 pp -- int.I2D: IntAct_Yeast
RUVBL1 8607 HSD17B12 51144 pp -- int.I2D: IntAct_Yeast
PSMD1 5707 HSD17B12 51144 pp -- int.I2D: BioGrid_Worm, BIND_Worm
ACTB 60 CFL1 1072 pp -- int.Intact: MI:0915(physical association);
int.I2D: BioGrid_Yeast, MINT_Yeast, MIPS, BioGrid, BIND_Yeast, HPRD, IntAct, IntAct_Yeast, MINT, VidalHuman_core, YeastLow, Yu_GoldStd;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
ACTB 60 RUVBL1 8607 pp -- int.I2D: IntAct_Yeast, BioGrid, BioGrid_Yeast
PSMD11 5717 RUVBL1 8607 pp -- int.I2D: YeastLow
CFL1 1072 PGD 5226 pp -- int.I2D: YeastLow
CFL1 1072 RUVBL1 8607 pp -- int.I2D: YeastLow

Related GO terms (198)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0016071mRNA metabolic process3.46e-084.99e-044.793631223
GO:0016070RNA metabolic process6.36e-089.17e-044.645632247
GO:0070062extracellular vesicular exosome5.90e-078.51e-032.239111042400
GO:0016020membrane4.50e-066.49e-022.4649901681
GO:0016032viral process5.84e-068.42e-023.533655534
GO:0006521regulation of cellular amino acid metabolic process1.39e-052.00e-015.95031750
GO:0010467gene expression2.12e-053.06e-013.208659669
GO:0000502proteasome complex2.18e-053.14e-015.73631758
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest2.93e-054.22e-015.59431964
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.07e-054.43e-015.57132265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle3.84e-055.53e-015.46432270
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent4.17e-056.02e-015.42432072
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle4.53e-056.54e-015.38432274
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I4.72e-056.80e-015.36532075
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process5.51e-057.95e-015.29032379
GO:0005838proteasome regulatory particle5.74e-058.28e-017.4242712
GO:0044267cellular protein metabolic process5.88e-058.48e-013.442529474
GO:0019083viral transcription5.94e-058.57e-015.25431081
GO:0006415translational termination7.35e-051.00e+005.15131087
GO:0035267NuA4 histone acetyltransferase complex7.91e-051.00e+007.2012414
GO:0002474antigen processing and presentation of peptide antigen via MHC class I8.69e-051.00e+005.07032192
GO:0006414translational elongation8.97e-051.00e+005.05531393
GO:0022624proteasome accessory complex1.18e-041.00e+006.9212817
GO:0005829cytosol1.19e-041.00e+001.89391322496
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.25e-041.00e+004.893310104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.64e-041.00e+004.761311114
GO:0019058viral life cycle1.69e-041.00e+004.748313115
GO:0000209protein polyubiquitination1.73e-041.00e+004.736320116
GO:0006413translational initiation2.48e-041.00e+004.560317131
GO:0003735structural constituent of ribosome2.83e-041.00e+004.496310137
GO:0000082G1/S transition of mitotic cell cycle3.62e-041.00e+004.375332149
GO:0042981regulation of apoptotic process3.69e-041.00e+004.365324150
GO:0034641cellular nitrogen compound metabolic process5.41e-041.00e+004.176320171
GO:0043066negative regulation of apoptotic process5.83e-041.00e+003.281431424
GO:0019521D-gluconate metabolic process9.71e-041.00e+0010.009111
GO:0022625cytosolic large ribosomal subunit1.00e-031.00e+005.3942649
GO:0006412translation1.28e-031.00e+003.748320230
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.94e-031.00e+009.009112
GO:0019322pentose biosynthetic process1.94e-031.00e+009.009122
GO:0005055laminin receptor activity1.94e-031.00e+009.009112
GO:0006407rRNA export from nucleus1.94e-031.00e+009.009112
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.27e-031.00e+004.7992674
GO:0005654nucleoplasm2.66e-031.00e+002.2515761082
GO:0001842neural fold formation2.91e-031.00e+008.424113
GO:0009051pentose-phosphate shunt, oxidative branch2.91e-031.00e+008.424123
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity2.91e-031.00e+008.424113
GO:0016363nuclear matrix3.41e-031.00e+004.50121291
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)3.88e-031.00e+008.009114
GO:003068690S preribosome3.88e-031.00e+008.009114
GO:0044281small molecule metabolic process4.35e-031.00e+002.0895581211
GO:0005925focal adhesion4.79e-031.00e+003.078319366
GO:0004303estradiol 17-beta-dehydrogenase activity4.84e-031.00e+007.687115
GO:0043248proteasome assembly4.84e-031.00e+007.687115
GO:0003923GPI-anchor transamidase activity4.84e-031.00e+007.687115
GO:0042765GPI-anchor transamidase complex4.84e-031.00e+007.687115
GO:0030529ribonucleoprotein complex5.12e-031.00e+004.20128112
GO:0006325chromatin organization5.66e-031.00e+004.12625118
GO:0000278mitotic cell cycle5.76e-031.00e+002.983348391
GO:0030957Tat protein binding5.81e-031.00e+007.424136
GO:0006703estrogen biosynthetic process5.81e-031.00e+007.424116
GO:0030836positive regulation of actin filament depolymerization5.81e-031.00e+007.424126
GO:0009615response to virus6.43e-031.00e+004.03125126
GO:0033180proton-transporting V-type ATPase, V1 domain6.78e-031.00e+007.201127
GO:0016255attachment of GPI anchor to protein6.78e-031.00e+007.201117
GO:0000028ribosomal small subunit assembly6.78e-031.00e+007.201117
GO:0034235GPI anchor binding6.78e-031.00e+007.201117
GO:0019773proteasome core complex, alpha-subunit complex7.74e-031.00e+007.009148
GO:0070688MLL5-L complex7.74e-031.00e+007.009118
GO:0030042actin filament depolymerization7.74e-031.00e+007.009128
GO:0000812Swr1 complex7.74e-031.00e+007.009138
GO:0006457protein folding8.22e-031.00e+003.84927143
GO:0006098pentose-phosphate shunt9.67e-031.00e+006.6871410
GO:0061001regulation of dendritic spine morphogenesis1.06e-021.00e+006.5491211
GO:0043968histone H2A acetylation1.16e-021.00e+006.4241312
GO:0042273ribosomal large subunit biogenesis1.26e-021.00e+006.3081413
GO:0035338long-chain fatty-acyl-CoA biosynthetic process1.26e-021.00e+006.3081313
GO:0030234enzyme regulator activity1.26e-021.00e+006.3081313
GO:0031011Ino80 complex1.35e-021.00e+006.2011314
GO:0046961proton-transporting ATPase activity, rotational mechanism1.45e-021.00e+006.1021315
GO:0046034ATP metabolic process1.45e-021.00e+006.1021115
GO:0006915apoptotic process1.50e-021.00e+002.477333555
GO:0050998nitric-oxide synthase binding1.54e-021.00e+006.0091116
GO:0042176regulation of protein catabolic process1.54e-021.00e+006.0091316
GO:0031258lamellipodium membrane1.54e-021.00e+006.0091216
GO:0022604regulation of cell morphogenesis1.54e-021.00e+006.0091116
GO:0003678DNA helicase activity1.64e-021.00e+005.9211317
GO:0005839proteasome core complex1.73e-021.00e+005.8391818
GO:0015078hydrogen ion transmembrane transporter activity1.83e-021.00e+005.7611319
GO:0048863stem cell differentiation1.83e-021.00e+005.7611119
GO:0004298threonine-type endopeptidase activity1.83e-021.00e+005.7611819
GO:0030010establishment of cell polarity2.02e-021.00e+005.6161221
GO:0000281mitotic cytokinesis2.02e-021.00e+005.6161121
GO:0003756protein disulfide isomerase activity2.12e-021.00e+005.5491122
GO:0030863cortical cytoskeleton2.12e-021.00e+005.5491122
GO:0036464cytoplasmic ribonucleoprotein granule2.12e-021.00e+005.5491422
GO:0043044ATP-dependent chromatin remodeling2.21e-021.00e+005.4851423
GO:0030864cortical actin cytoskeleton2.21e-021.00e+005.4851123
GO:0043236laminin binding2.21e-021.00e+005.4851123
GO:0043200response to amino acid2.21e-021.00e+005.4851123
GO:0034080CENP-A containing nucleosome assembly2.40e-021.00e+005.3651125
GO:0001968fibronectin binding2.40e-021.00e+005.3651225
GO:0005515protein binding2.44e-021.00e+000.774101846024
GO:0015991ATP hydrolysis coupled proton transport2.50e-021.00e+005.3081426
GO:0006501C-terminal protein lipidation2.50e-021.00e+005.3081226
GO:0043022ribosome binding2.59e-021.00e+005.2541327
GO:0050661NADP binding2.59e-021.00e+005.2541227
GO:0071339MLL1 complex2.59e-021.00e+005.2541327
GO:0043967histone H4 acetylation2.59e-021.00e+005.2541327
GO:0031492nucleosomal DNA binding2.59e-021.00e+005.2541427
GO:0001755neural crest cell migration2.69e-021.00e+005.2011228
GO:0019894kinesin binding2.69e-021.00e+005.2011128
GO:0015992proton transport2.78e-021.00e+005.1511329
GO:0019432triglyceride biosynthetic process2.87e-021.00e+005.1021330
GO:0042254ribosome biogenesis2.87e-021.00e+005.1021130
GO:0033572transferrin transport2.87e-021.00e+005.1021530
GO:0010811positive regulation of cell-substrate adhesion2.97e-021.00e+005.0551231
GO:0006633fatty acid biosynthetic process3.06e-021.00e+005.0091332
GO:0051701interaction with host3.06e-021.00e+005.0091432
GO:0001895retina homeostasis3.25e-021.00e+004.9211134
GO:0034332adherens junction organization3.44e-021.00e+004.8391136
GO:0090382phagosome maturation3.44e-021.00e+004.8391536
GO:0051084'de novo' posttranslational protein folding3.53e-021.00e+004.7991437
GO:0005902microvillus3.63e-021.00e+004.7611238
GO:0070527platelet aggregation3.63e-021.00e+004.7611238
GO:0043231intracellular membrane-bounded organelle3.70e-021.00e+002.69629318
GO:0022627cytosolic small ribosomal subunit3.72e-021.00e+004.7231439
GO:0007411axon guidance3.72e-021.00e+002.691213319
GO:0032508DNA duplex unwinding3.91e-021.00e+004.6511341
GO:0021762substantia nigra development4.19e-021.00e+004.5491244
GO:0003723RNA binding4.23e-021.00e+002.591220342
GO:0007266Rho protein signal transduction4.47e-021.00e+004.4541247
GO:0004197cysteine-type endopeptidase activity4.75e-021.00e+004.3651350
GO:0040008regulation of growth4.75e-021.00e+004.3651550
GO:0006879cellular iron ion homeostasis4.84e-021.00e+004.3361451
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding5.03e-021.00e+004.2811553
GO:0030176integral component of endoplasmic reticulum membrane5.03e-021.00e+004.2811253
GO:0005518collagen binding5.12e-021.00e+004.2541154
GO:0045216cell-cell junction organization5.12e-021.00e+004.2541254
GO:0000932cytoplasmic mRNA processing body5.12e-021.00e+004.2541354
GO:0012505endomembrane system5.30e-021.00e+004.2011256
GO:0055114oxidation-reduction process6.11e-021.00e+002.294212420
GO:0006310DNA recombination6.13e-021.00e+003.9861265
GO:0034329cell junction assembly6.40e-021.00e+003.9211168
GO:0032587ruffle membrane6.59e-021.00e+003.8791370
GO:0006334nucleosome assembly6.77e-021.00e+003.8391272
GO:0007596blood coagulation7.04e-021.00e+002.179218455
GO:0001726ruffle7.49e-021.00e+003.6871480
GO:0002576platelet degranulation7.68e-021.00e+003.6511482
GO:0044822poly(A) RNA binding7.77e-021.00e+001.5493491056
GO:0007010cytoskeleton organization8.48e-021.00e+003.5011191
GO:0042470melanosome8.48e-021.00e+003.5011991
GO:0006928cellular component movement8.48e-021.00e+003.5011791
GO:0005200structural constituent of cytoskeleton8.48e-021.00e+003.5011891
GO:0006364rRNA processing8.75e-021.00e+003.4541694
GO:0014069postsynaptic density9.73e-021.00e+003.29413105
GO:0005815microtubule organizing center1.01e-011.00e+003.24115109
GO:0072562blood microparticle1.03e-011.00e+003.21413111
GO:0005789endoplasmic reticulum membrane1.04e-011.00e+001.854216570
GO:0008201heparin binding1.12e-011.00e+003.07814122
GO:0045087innate immune response1.12e-011.00e+001.790224596
GO:0030036actin cytoskeleton organization1.13e-011.00e+003.06615123
GO:0006511ubiquitin-dependent protein catabolic process1.16e-011.00e+003.03115126
GO:0000790nuclear chromatin1.18e-011.00e+002.99819129
GO:0005634nucleus1.18e-011.00e+000.66271364559
GO:0031982vesicle1.20e-011.00e+002.97519131
GO:0044255cellular lipid metabolic process1.22e-011.00e+002.95316133
GO:0005911cell-cell junction1.24e-011.00e+002.92114136
GO:0005524ATP binding1.25e-011.00e+001.2523601298
GO:0016887ATPase activity1.28e-011.00e+002.87917140
GO:0008286insulin receptor signaling pathway1.29e-011.00e+002.85917142
GO:0005737cytoplasm1.32e-011.00e+000.71461103767
GO:0061024membrane organization1.32e-011.00e+002.82917145
GO:0031012extracellular matrix1.40e-011.00e+002.74212154
GO:0043687post-translational protein modification1.46e-011.00e+002.66915162
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.49e-011.00e+002.64217165
GO:0030424axon1.50e-011.00e+002.63414166
GO:0005765lysosomal membrane1.80e-011.00e+002.34315203
GO:0030168platelet activation1.82e-011.00e+002.329110205
GO:0007067mitotic nuclear division1.99e-011.00e+002.182114227
GO:0005975carbohydrate metabolic process2.20e-011.00e+002.02619253
GO:0007283spermatogenesis2.26e-011.00e+001.97518262
GO:0006281DNA repair2.26e-011.00e+001.981118261
GO:0006357regulation of transcription from RNA polymerase II promoter2.28e-011.00e+001.96418264
GO:0003779actin binding2.30e-011.00e+001.953112266
GO:0005615extracellular space2.37e-011.00e+001.106217957
GO:0030198extracellular matrix organization2.42e-011.00e+001.86414283
GO:0005856cytoskeleton2.48e-011.00e+001.824112291
GO:0043234protein complex2.51e-011.00e+001.804118295
GO:0019901protein kinase binding2.67e-011.00e+001.700121317
GO:0007155cell adhesion3.04e-011.00e+001.48116369
GO:0006508proteolysis3.11e-011.00e+001.44619378
GO:0055085transmembrane transport3.49e-011.00e+001.244110435
GO:0006468protein phosphorylation3.65e-011.00e+001.163118460
GO:0005794Golgi apparatus4.54e-011.00e+000.756115610
GO:0005730nucleolus4.84e-011.00e+000.3282691641
GO:0016021integral component of membrane5.92e-011.00e+000.0562271982
GO:0005886plasma membrane7.44e-011.00e+00-0.3262452582
GO:0006351transcription, DNA-templated7.72e-011.00e+00-0.4891311446