| Dataset | Score | p-value 1 | p-value 2 | p-value 3 | 
|---|---|---|---|---|
| wolf-screen-ratio-mammosphere-adherent | 0.988 | 1.25e-17 | 7.39e-04 | 1.64e-02 | 

| Gene Symbol | Entrez Gene ID | Frequency | wolf-screen-ratio-mammosphere-adherent gene score | Best subnetwork score | Degree | wolf adherent-list Hits GI | wolf mammosphere no adherent-list Hits GI | 
|---|---|---|---|---|---|---|---|
| RPA2 | 6118 | 98 | 1.250 | 1.151 | 69 | Yes | - | 
| ACO2 | 50 | 50 | 1.000 | 1.076 | 191 | Yes | - | 
| RBX1 | 9978 | 97 | 1.185 | 1.151 | 139 | Yes | - | 
| PSMD3 | 5709 | 57 | 0.986 | 1.106 | 146 | Yes | - | 
| PSMB7 | 5695 | 48 | 0.982 | 1.052 | 57 | Yes | - | 
| PSMA1 | 5682 | 61 | 0.996 | 1.052 | 123 | Yes | - | 
| PSMD11 | 5717 | 121 | 1.095 | 1.106 | 183 | Yes | - | 
| ACTB | 60 | 167 | 1.153 | 1.151 | 587 | Yes | - | 
| POLR1B | 84172 | 4 | 0.613 | 0.988 | 184 | Yes | - | 
| FBL | 2091 | 7 | 0.839 | 1.151 | 65 | Yes | - | 
| RPSA | 3921 | 156 | 1.327 | 1.151 | 152 | Yes | - | 
| [ MYO1C ] | 4641 | 1 | 0.218 | 0.988 | 35 | - | - | 
| PGD | 5226 | 75 | 1.201 | 1.106 | 138 | Yes | - | 
| Gene Symbol 1 | Entrez Gene ID 1 | Gene Symbol 2 | Entrez Gene ID 2 | Type | Direction | Origin databases / Sources | 
|---|---|---|---|---|---|---|
| PSMD3 | 5709 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG | 
| PSMD3 | 5709 | POLR1B | 84172 | pp | -- | int.I2D: IntAct_Yeast, YeastLow | 
| ACTB | 60 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast | 
| PGD | 5226 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow | 
| PGD | 5226 | PSMD3 | 5709 | pp | -- | int.I2D: YeastLow | 
| PSMB7 | 5695 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast | 
| PSMB7 | 5695 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast | 
| PGD | 5226 | POLR1B | 84172 | pp | -- | int.I2D: YeastLow | 
| ACTB | 60 | MYO1C | 4641 | pp | -- | int.I2D: BIND_Mouse | 
| ACTB | 60 | PSMA1 | 5682 | pp | -- | int.I2D: BioGrid_Yeast | 
| ACO2 | 50 | POLR1B | 84172 | pp | -- | int.I2D: YeastLow | 
| ACTB | 60 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast | 
| ACTB | 60 | FBL | 2091 | pp | -- | int.I2D: MINT | 
| PSMA1 | 5682 | PSMD3 | 5709 | pp | -- | int.I2D: BioGrid_Yeast, YeastMedium | 
| ACTB | 60 | POLR1B | 84172 | pp | -- | int.I2D: BIND, BIND_Mouse | 
| RPSA | 3921 | PSMD11 | 5717 | pp | -- | int.I2D: IntAct_Yeast | 
| PSMA1 | 5682 | PSMD11 | 5717 | pp | -- | int.I2D: BioGrid_Yeast, YeastLow | 
| ACTB | 60 | RPSA | 3921 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct_Yeast, IntAct | 
| PSMA1 | 5682 | PSMB7 | 5695 | pp | -- | int.Intact: MI:0914(association); int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast | 
| ACTB | 60 | RBX1 | 9978 | pp | -- | int.I2D: BioGrid_Yeast | 
| ACTB | 60 | PSMB7 | 5695 | pp | -- | int.I2D: BioGrid_Yeast | 
| FBL | 2091 | MYO1C | 4641 | pp | -- | int.Intact: MI:0403(colocalization); int.I2D: BCI, IntAct | 
| PSMD11 | 5717 | POLR1B | 84172 | pp | -- | int.I2D: YeastLow | 
| ACO2 | 50 | PSMD11 | 5717 | pp | -- | int.I2D: YeastLow | 
| ACTB | 60 | RPA2 | 6118 | pp | -- | int.Intact: MI:0915(physical association); int.I2D: IntAct | 
| ACO2 | 50 | PGD | 5226 | pp | -- | int.I2D: YeastLow | 
| MYO1C | 4641 | POLR1B | 84172 | pp | -- | int.Intact: MI:0403(colocalization); int.I2D: IntAct | 
| Accession number | Name | Hypergeometric test | Corrected p-value | Enrichment ratio | Occurrence in subnetwork | Occurrences in all snw genes | Occurrences in all int/reg genes | 
|---|---|---|---|---|---|---|---|
| GO:0005654 | nucleoplasm | 3.95e-08 | 5.70e-04 | 3.206 | 9 | 76 | 1082 | 
| GO:0006521 | regulation of cellular amino acid metabolic process | 8.93e-08 | 1.29e-03 | 6.472 | 4 | 17 | 50 | 
| GO:0000082 | G1/S transition of mitotic cell cycle | 1.32e-07 | 1.91e-03 | 5.218 | 5 | 32 | 149 | 
| GO:0000502 | proteasome complex | 1.64e-07 | 2.36e-03 | 6.258 | 4 | 17 | 58 | 
| GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | 2.45e-07 | 3.53e-03 | 6.116 | 4 | 19 | 64 | 
| GO:0051436 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 2.61e-07 | 3.76e-03 | 6.093 | 4 | 22 | 65 | 
| GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 3.52e-07 | 5.08e-03 | 5.986 | 4 | 22 | 70 | 
| GO:0002479 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | 3.94e-07 | 5.69e-03 | 5.946 | 4 | 20 | 72 | 
| GO:0051439 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle | 4.41e-07 | 6.36e-03 | 5.906 | 4 | 22 | 74 | 
| GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I | 4.65e-07 | 6.71e-03 | 5.887 | 4 | 20 | 75 | 
| GO:0031145 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process | 5.74e-07 | 8.28e-03 | 5.812 | 4 | 23 | 79 | 
| GO:0016071 | mRNA metabolic process | 9.83e-07 | 1.42e-02 | 4.637 | 5 | 31 | 223 | 
| GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I | 1.06e-06 | 1.53e-02 | 5.592 | 4 | 21 | 92 | 
| GO:0016070 | RNA metabolic process | 1.63e-06 | 2.35e-02 | 4.489 | 5 | 32 | 247 | 
| GO:0000209 | protein polyubiquitination | 2.69e-06 | 3.87e-02 | 5.258 | 4 | 20 | 116 | 
| GO:0016032 | viral process | 3.44e-06 | 4.96e-02 | 3.640 | 6 | 55 | 534 | 
| GO:0042981 | regulation of apoptotic process | 7.47e-06 | 1.08e-01 | 4.887 | 4 | 24 | 150 | 
| GO:0034641 | cellular nitrogen compound metabolic process | 1.25e-05 | 1.81e-01 | 4.698 | 4 | 20 | 171 | 
| GO:0010467 | gene expression | 1.26e-05 | 1.82e-01 | 3.315 | 6 | 59 | 669 | 
| GO:0000278 | mitotic cell cycle | 1.54e-05 | 2.21e-01 | 3.827 | 5 | 48 | 391 | 
| GO:0070062 | extracellular vesicular exosome | 3.62e-05 | 5.23e-01 | 2.057 | 9 | 104 | 2400 | 
| GO:0005838 | proteasome regulatory particle | 4.92e-05 | 7.10e-01 | 7.531 | 2 | 7 | 12 | 
| GO:0005829 | cytosol | 5.02e-05 | 7.24e-01 | 2.000 | 9 | 132 | 2496 | 
| GO:0022624 | proteasome accessory complex | 1.01e-04 | 1.00e+00 | 7.028 | 2 | 8 | 17 | 
| GO:0005839 | proteasome core complex | 1.14e-04 | 1.00e+00 | 6.946 | 2 | 8 | 18 | 
| GO:0004298 | threonine-type endopeptidase activity | 1.27e-04 | 1.00e+00 | 6.868 | 2 | 8 | 19 | 
| GO:0005730 | nucleolus | 2.24e-04 | 1.00e+00 | 2.243 | 7 | 69 | 1641 | 
| GO:0044281 | small molecule metabolic process | 3.54e-04 | 1.00e+00 | 2.459 | 6 | 58 | 1211 | 
| GO:0043066 | negative regulation of apoptotic process | 4.26e-04 | 1.00e+00 | 3.388 | 4 | 31 | 424 | 
| GO:1990259 | histone-glutamine methyltransferase activity | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 | 
| GO:0038089 | positive regulation of cell migration by vascular endothelial growth factor signaling pathway | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 | 
| GO:1990258 | histone glutamine methylation | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 | 
| GO:0045160 | myosin I complex | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 | 
| GO:0019521 | D-gluconate metabolic process | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 | 
| GO:0016074 | snoRNA metabolic process | 9.01e-04 | 1.00e+00 | 10.116 | 1 | 1 | 1 | 
| GO:0005634 | nucleus | 1.03e-03 | 1.00e+00 | 1.283 | 10 | 136 | 4559 | 
| GO:0006915 | apoptotic process | 1.17e-03 | 1.00e+00 | 2.999 | 4 | 33 | 555 | 
| GO:0051538 | 3 iron, 4 sulfur cluster binding | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 | 
| GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 | 
| GO:0060171 | stereocilium membrane | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 | 
| GO:0000461 | endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 | 
| GO:0019322 | pentose biosynthetic process | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 2 | 2 | 
| GO:0003994 | aconitate hydratase activity | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 | 
| GO:0005055 | laminin receptor activity | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 | 
| GO:0006407 | rRNA export from nucleus | 1.80e-03 | 1.00e+00 | 9.116 | 1 | 1 | 2 | 
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | 1.95e-03 | 1.00e+00 | 4.906 | 2 | 6 | 74 | 
| GO:0016020 | membrane | 2.06e-03 | 1.00e+00 | 1.986 | 6 | 90 | 1681 | 
| GO:0009051 | pentose-phosphate shunt, oxidative branch | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 2 | 3 | 
| GO:0004616 | phosphogluconate dehydrogenase (decarboxylating) activity | 2.70e-03 | 1.00e+00 | 8.531 | 1 | 1 | 3 | 
| GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 | 
| GO:0030686 | 90S preribosome | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 | 
| GO:0031467 | Cul7-RING ubiquitin ligase complex | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 | 
| GO:0019788 | NEDD8 ligase activity | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 | 
| GO:0001652 | granular component | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 | 
| GO:0032549 | ribonucleoside binding | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 2 | 4 | 
| GO:0031428 | box C/D snoRNP complex | 3.60e-03 | 1.00e+00 | 8.116 | 1 | 1 | 4 | 
| GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 3 | 5 | 
| GO:0031461 | cullin-RING ubiquitin ligase complex | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 | 
| GO:0043248 | proteasome assembly | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 | 
| GO:0006102 | isocitrate metabolic process | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 | 
| GO:0030891 | VCB complex | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 2 | 5 | 
| GO:0000730 | DNA recombinase assembly | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 | 
| GO:2000001 | regulation of DNA damage checkpoint | 4.50e-03 | 1.00e+00 | 7.794 | 1 | 1 | 5 | 
| GO:0030957 | Tat protein binding | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 3 | 6 | 
| GO:0006101 | citrate metabolic process | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 1 | 6 | 
| GO:0031466 | Cul5-RING ubiquitin ligase complex | 5.40e-03 | 1.00e+00 | 7.531 | 1 | 1 | 6 | 
| GO:0016461 | unconventional myosin complex | 6.29e-03 | 1.00e+00 | 7.308 | 1 | 1 | 7 | 
| GO:0000028 | ribosomal small subunit assembly | 6.29e-03 | 1.00e+00 | 7.308 | 1 | 1 | 7 | 
| GO:0031462 | Cul2-RING ubiquitin ligase complex | 6.29e-03 | 1.00e+00 | 7.308 | 1 | 2 | 7 | 
| GO:0019773 | proteasome core complex, alpha-subunit complex | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 4 | 8 | 
| GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 2 | 8 | 
| GO:0070688 | MLL5-L complex | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 1 | 8 | 
| GO:0045116 | protein neddylation | 7.19e-03 | 1.00e+00 | 7.116 | 1 | 2 | 8 | 
| GO:0061024 | membrane organization | 7.28e-03 | 1.00e+00 | 3.936 | 2 | 7 | 145 | 
| GO:2000810 | regulation of tight junction assembly | 8.09e-03 | 1.00e+00 | 6.946 | 1 | 2 | 9 | 
| GO:0006098 | pentose-phosphate shunt | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 4 | 10 | 
| GO:0010569 | regulation of double-strand break repair via homologous recombination | 8.98e-03 | 1.00e+00 | 6.794 | 1 | 1 | 10 | 
| GO:0031571 | mitotic G1 DNA damage checkpoint | 9.87e-03 | 1.00e+00 | 6.656 | 1 | 4 | 11 | 
| GO:0031625 | ubiquitin protein ligase binding | 1.08e-02 | 1.00e+00 | 3.640 | 2 | 14 | 178 | 
| GO:0030898 | actin-dependent ATPase activity | 1.08e-02 | 1.00e+00 | 6.531 | 1 | 1 | 12 | 
| GO:0005515 | protein binding | 1.11e-02 | 1.00e+00 | 0.881 | 10 | 184 | 6024 | 
| GO:0005662 | DNA replication factor A complex | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 1 | 13 | 
| GO:0030234 | enzyme regulator activity | 1.17e-02 | 1.00e+00 | 6.415 | 1 | 3 | 13 | 
| GO:0035267 | NuA4 histone acetyltransferase complex | 1.26e-02 | 1.00e+00 | 6.308 | 1 | 4 | 14 | 
| GO:0050998 | nitric-oxide synthase binding | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 | 
| GO:0090314 | positive regulation of protein targeting to membrane | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 1 | 16 | 
| GO:0042176 | regulation of protein catabolic process | 1.43e-02 | 1.00e+00 | 6.116 | 1 | 3 | 16 | 
| GO:0035861 | site of double-strand break | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 18 | 
| GO:0006612 | protein targeting to membrane | 1.61e-02 | 1.00e+00 | 5.946 | 1 | 1 | 18 | 
| GO:0031146 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 1 | 19 | 
| GO:0048863 | stem cell differentiation | 1.70e-02 | 1.00e+00 | 5.868 | 1 | 1 | 19 | 
| GO:0006298 | mismatch repair | 1.79e-02 | 1.00e+00 | 5.794 | 1 | 3 | 20 | 
| GO:0032201 | telomere maintenance via semi-conservative replication | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 5 | 21 | 
| GO:0000718 | nucleotide-excision repair, DNA damage removal | 1.88e-02 | 1.00e+00 | 5.723 | 1 | 4 | 21 | 
| GO:0031941 | filamentous actin | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 1 | 22 | 
| GO:0006297 | nucleotide-excision repair, DNA gap filling | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 3 | 22 | 
| GO:0030863 | cortical cytoskeleton | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 1 | 22 | 
| GO:0036464 | cytoplasmic ribonucleoprotein granule | 1.97e-02 | 1.00e+00 | 5.656 | 1 | 4 | 22 | 
| GO:0043044 | ATP-dependent chromatin remodeling | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 4 | 23 | 
| GO:0005844 | polysome | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 4 | 23 | 
| GO:0005903 | brush border | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 1 | 23 | 
| GO:0006362 | transcription elongation from RNA polymerase I promoter | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 3 | 23 | 
| GO:0031463 | Cul3-RING ubiquitin ligase complex | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 3 | 23 | 
| GO:0043236 | laminin binding | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 1 | 23 | 
| GO:0006513 | protein monoubiquitination | 2.05e-02 | 1.00e+00 | 5.592 | 1 | 1 | 23 | 
| GO:0006363 | termination of RNA polymerase I transcription | 2.14e-02 | 1.00e+00 | 5.531 | 1 | 3 | 24 | 
| GO:0003899 | DNA-directed RNA polymerase activity | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 3 | 25 | 
| GO:0000722 | telomere maintenance via recombination | 2.23e-02 | 1.00e+00 | 5.472 | 1 | 5 | 25 | 
| GO:0006281 | DNA repair | 2.23e-02 | 1.00e+00 | 3.088 | 2 | 18 | 261 | 
| GO:0006361 | transcription initiation from RNA polymerase I promoter | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 3 | 26 | 
| GO:0061418 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | 2.32e-02 | 1.00e+00 | 5.415 | 1 | 3 | 26 | 
| GO:0043022 | ribosome binding | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 3 | 27 | 
| GO:0009925 | basal plasma membrane | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 1 | 27 | 
| GO:0050661 | NADP binding | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 2 | 27 | 
| GO:0031492 | nucleosomal DNA binding | 2.41e-02 | 1.00e+00 | 5.361 | 1 | 4 | 27 | 
| GO:0006099 | tricarboxylic acid cycle | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 4 | 28 | 
| GO:0019894 | kinesin binding | 2.50e-02 | 1.00e+00 | 5.308 | 1 | 1 | 28 | 
| GO:0019005 | SCF ubiquitin ligase complex | 2.58e-02 | 1.00e+00 | 5.258 | 1 | 1 | 29 | 
| GO:0006360 | transcription from RNA polymerase I promoter | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 5 | 30 | 
| GO:0006271 | DNA strand elongation involved in DNA replication | 2.67e-02 | 1.00e+00 | 5.209 | 1 | 7 | 30 | 
| GO:0001895 | retina homeostasis | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 1 | 34 | 
| GO:0008033 | tRNA processing | 3.02e-02 | 1.00e+00 | 5.028 | 1 | 1 | 34 | 
| GO:0006605 | protein targeting | 3.11e-02 | 1.00e+00 | 4.986 | 1 | 2 | 35 | 
| GO:0051539 | 4 iron, 4 sulfur cluster binding | 3.11e-02 | 1.00e+00 | 4.986 | 1 | 3 | 35 | 
| GO:0034332 | adherens junction organization | 3.20e-02 | 1.00e+00 | 4.946 | 1 | 1 | 36 | 
| GO:0051084 | 'de novo' posttranslational protein folding | 3.29e-02 | 1.00e+00 | 4.906 | 1 | 4 | 37 | 
| GO:0006284 | base-excision repair | 3.29e-02 | 1.00e+00 | 4.906 | 1 | 3 | 37 | 
| GO:0005902 | microvillus | 3.37e-02 | 1.00e+00 | 4.868 | 1 | 2 | 38 | 
| GO:0070527 | platelet aggregation | 3.37e-02 | 1.00e+00 | 4.868 | 1 | 2 | 38 | 
| GO:0022627 | cytosolic small ribosomal subunit | 3.46e-02 | 1.00e+00 | 4.830 | 1 | 4 | 39 | 
| GO:0000781 | chromosome, telomeric region | 3.46e-02 | 1.00e+00 | 4.830 | 1 | 3 | 39 | 
| GO:0003723 | RNA binding | 3.68e-02 | 1.00e+00 | 2.698 | 2 | 20 | 342 | 
| GO:0003774 | motor activity | 3.81e-02 | 1.00e+00 | 4.689 | 1 | 2 | 43 | 
| GO:0021762 | substantia nigra development | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 2 | 44 | 
| GO:0015030 | Cajal body | 3.90e-02 | 1.00e+00 | 4.656 | 1 | 3 | 44 | 
| GO:0006283 | transcription-coupled nucleotide-excision repair | 4.07e-02 | 1.00e+00 | 4.592 | 1 | 7 | 46 | 
| GO:0016328 | lateral plasma membrane | 4.07e-02 | 1.00e+00 | 4.592 | 1 | 1 | 46 | 
| GO:0003684 | damaged DNA binding | 4.33e-02 | 1.00e+00 | 4.501 | 1 | 7 | 49 | 
| GO:0006091 | generation of precursor metabolites and energy | 4.42e-02 | 1.00e+00 | 4.472 | 1 | 3 | 50 | 
| GO:0051028 | mRNA transport | 4.59e-02 | 1.00e+00 | 4.415 | 1 | 2 | 52 | 
| GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding | 4.68e-02 | 1.00e+00 | 4.388 | 1 | 5 | 53 | 
| GO:0045216 | cell-cell junction organization | 4.76e-02 | 1.00e+00 | 4.361 | 1 | 2 | 54 | 
| GO:0001725 | stress fiber | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 2 | 55 | 
| GO:0000724 | double-strand break repair via homologous recombination | 4.85e-02 | 1.00e+00 | 4.334 | 1 | 3 | 55 | 
| GO:0000723 | telomere maintenance | 4.93e-02 | 1.00e+00 | 4.308 | 1 | 6 | 56 | 
| GO:0005643 | nuclear pore | 5.02e-02 | 1.00e+00 | 4.283 | 1 | 4 | 57 | 
| GO:0019903 | protein phosphatase binding | 5.45e-02 | 1.00e+00 | 4.161 | 1 | 4 | 62 | 
| GO:0006302 | double-strand break repair | 5.45e-02 | 1.00e+00 | 4.161 | 1 | 4 | 62 | 
| GO:0006289 | nucleotide-excision repair | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 11 | 68 | 
| GO:0034329 | cell junction assembly | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 1 | 68 | 
| GO:0003697 | single-stranded DNA binding | 5.96e-02 | 1.00e+00 | 4.028 | 1 | 5 | 68 | 
| GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process | 6.56e-02 | 1.00e+00 | 3.887 | 1 | 2 | 75 | 
| GO:0044267 | cellular protein metabolic process | 6.62e-02 | 1.00e+00 | 2.227 | 2 | 29 | 474 | 
| GO:0001726 | ruffle | 6.98e-02 | 1.00e+00 | 3.794 | 1 | 4 | 80 | 
| GO:0019083 | viral transcription | 7.06e-02 | 1.00e+00 | 3.776 | 1 | 10 | 81 | 
| GO:0047485 | protein N-terminus binding | 7.48e-02 | 1.00e+00 | 3.689 | 1 | 5 | 86 | 
| GO:0006415 | translational termination | 7.57e-02 | 1.00e+00 | 3.673 | 1 | 10 | 87 | 
| GO:0016605 | PML body | 7.65e-02 | 1.00e+00 | 3.656 | 1 | 3 | 88 | 
| GO:0006928 | cellular component movement | 7.90e-02 | 1.00e+00 | 3.608 | 1 | 7 | 91 | 
| GO:0005200 | structural constituent of cytoskeleton | 7.90e-02 | 1.00e+00 | 3.608 | 1 | 8 | 91 | 
| GO:0001649 | osteoblast differentiation | 7.99e-02 | 1.00e+00 | 3.592 | 1 | 6 | 92 | 
| GO:0071456 | cellular response to hypoxia | 7.99e-02 | 1.00e+00 | 3.592 | 1 | 6 | 92 | 
| GO:0006414 | translational elongation | 8.07e-02 | 1.00e+00 | 3.576 | 1 | 13 | 93 | 
| GO:0006364 | rRNA processing | 8.15e-02 | 1.00e+00 | 3.561 | 1 | 6 | 94 | 
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | 8.98e-02 | 1.00e+00 | 3.415 | 1 | 10 | 104 | 
| GO:0014069 | postsynaptic density | 9.07e-02 | 1.00e+00 | 3.401 | 1 | 3 | 105 | 
| GO:0005506 | iron ion binding | 9.07e-02 | 1.00e+00 | 3.401 | 1 | 4 | 105 | 
| GO:0016023 | cytoplasmic membrane-bounded vesicle | 9.07e-02 | 1.00e+00 | 3.401 | 1 | 5 | 105 | 
| GO:0015630 | microtubule cytoskeleton | 9.48e-02 | 1.00e+00 | 3.334 | 1 | 4 | 110 | 
| GO:0072562 | blood microparticle | 9.56e-02 | 1.00e+00 | 3.321 | 1 | 3 | 111 | 
| GO:0030529 | ribonucleoprotein complex | 9.64e-02 | 1.00e+00 | 3.308 | 1 | 8 | 112 | 
| GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 9.81e-02 | 1.00e+00 | 3.283 | 1 | 11 | 114 | 
| GO:0045087 | innate immune response | 9.84e-02 | 1.00e+00 | 1.896 | 2 | 24 | 596 | 
| GO:0019058 | viral life cycle | 9.89e-02 | 1.00e+00 | 3.270 | 1 | 13 | 115 | 
| GO:0044237 | cellular metabolic process | 1.01e-01 | 1.00e+00 | 3.245 | 1 | 5 | 117 | 
| GO:0006325 | chromatin organization | 1.01e-01 | 1.00e+00 | 3.233 | 1 | 5 | 118 | 
| GO:0007219 | Notch signaling pathway | 1.03e-01 | 1.00e+00 | 3.209 | 1 | 5 | 120 | 
| GO:0006260 | DNA replication | 1.04e-01 | 1.00e+00 | 3.197 | 1 | 9 | 121 | 
| GO:0006511 | ubiquitin-dependent protein catabolic process | 1.08e-01 | 1.00e+00 | 3.138 | 1 | 5 | 126 | 
| GO:0030335 | positive regulation of cell migration | 1.09e-01 | 1.00e+00 | 3.127 | 1 | 7 | 127 | 
| GO:0000790 | nuclear chromatin | 1.10e-01 | 1.00e+00 | 3.104 | 1 | 9 | 129 | 
| GO:0006413 | translational initiation | 1.12e-01 | 1.00e+00 | 3.082 | 1 | 17 | 131 | 
| GO:0003735 | structural constituent of ribosome | 1.17e-01 | 1.00e+00 | 3.018 | 1 | 10 | 137 | 
| GO:0006457 | protein folding | 1.22e-01 | 1.00e+00 | 2.956 | 1 | 7 | 143 | 
| GO:0045121 | membrane raft | 1.32e-01 | 1.00e+00 | 2.830 | 1 | 8 | 156 | 
| GO:0005516 | calmodulin binding | 1.35e-01 | 1.00e+00 | 2.794 | 1 | 3 | 160 | 
| GO:0008022 | protein C-terminus binding | 1.36e-01 | 1.00e+00 | 2.785 | 1 | 5 | 161 | 
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | 1.39e-01 | 1.00e+00 | 2.749 | 1 | 7 | 165 | 
| GO:0030424 | axon | 1.40e-01 | 1.00e+00 | 2.741 | 1 | 4 | 166 | 
| GO:0032403 | protein complex binding | 1.53e-01 | 1.00e+00 | 2.600 | 1 | 10 | 183 | 
| GO:0005759 | mitochondrial matrix | 1.87e-01 | 1.00e+00 | 2.283 | 1 | 14 | 228 | 
| GO:0006412 | translation | 1.89e-01 | 1.00e+00 | 2.270 | 1 | 20 | 230 | 
| GO:0005975 | carbohydrate metabolic process | 2.06e-01 | 1.00e+00 | 2.133 | 1 | 9 | 253 | 
| GO:0004842 | ubiquitin-protein transferase activity | 2.07e-01 | 1.00e+00 | 2.121 | 1 | 6 | 255 | 
| GO:0005102 | receptor binding | 2.11e-01 | 1.00e+00 | 2.093 | 1 | 6 | 260 | 
| GO:0003779 | actin binding | 2.15e-01 | 1.00e+00 | 2.060 | 1 | 12 | 266 | 
| GO:0019899 | enzyme binding | 2.23e-01 | 1.00e+00 | 2.002 | 1 | 12 | 277 | 
| GO:0005739 | mitochondrion | 2.26e-01 | 1.00e+00 | 1.153 | 2 | 28 | 998 | 
| GO:0005856 | cytoskeleton | 2.33e-01 | 1.00e+00 | 1.931 | 1 | 12 | 291 | 
| GO:0006200 | ATP catabolic process | 2.34e-01 | 1.00e+00 | 1.926 | 1 | 15 | 292 | 
| GO:0005737 | cytoplasm | 2.35e-01 | 1.00e+00 | 0.558 | 5 | 110 | 3767 | 
| GO:0043234 | protein complex | 2.36e-01 | 1.00e+00 | 1.911 | 1 | 18 | 295 | 
| GO:0016567 | protein ubiquitination | 2.36e-01 | 1.00e+00 | 1.911 | 1 | 5 | 295 | 
| GO:0044822 | poly(A) RNA binding | 2.46e-01 | 1.00e+00 | 1.071 | 2 | 49 | 1056 | 
| GO:0019901 | protein kinase binding | 2.51e-01 | 1.00e+00 | 1.807 | 1 | 21 | 317 | 
| GO:0007411 | axon guidance | 2.52e-01 | 1.00e+00 | 1.798 | 1 | 13 | 319 | 
| GO:0005813 | centrosome | 2.57e-01 | 1.00e+00 | 1.767 | 1 | 14 | 326 | 
| GO:0005925 | focal adhesion | 2.84e-01 | 1.00e+00 | 1.600 | 1 | 19 | 366 | 
| GO:0007155 | cell adhesion | 2.86e-01 | 1.00e+00 | 1.588 | 1 | 6 | 369 | 
| GO:0055114 | oxidation-reduction process | 3.19e-01 | 1.00e+00 | 1.401 | 1 | 12 | 420 | 
| GO:0005524 | ATP binding | 3.29e-01 | 1.00e+00 | 0.774 | 2 | 60 | 1298 | 
| GO:0007596 | blood coagulation | 3.41e-01 | 1.00e+00 | 1.286 | 1 | 18 | 455 | 
| GO:0005615 | extracellular space | 5.91e-01 | 1.00e+00 | 0.213 | 1 | 17 | 957 | 
| GO:0008270 | zinc ion binding | 6.06e-01 | 1.00e+00 | 0.154 | 1 | 12 | 997 | 
| GO:0003677 | DNA binding | 6.83e-01 | 1.00e+00 | -0.135 | 1 | 28 | 1218 | 
| GO:0005886 | plasma membrane | 7.05e-01 | 1.00e+00 | -0.219 | 2 | 45 | 2582 | 
| GO:0046872 | metal ion binding | 7.09e-01 | 1.00e+00 | -0.236 | 1 | 25 | 1307 |