int-snw-302

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.938 1.18e-15 2.28e-03 3.78e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-302 subnetwork

Genes (18)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
RBX1 9978 971.1851.151139Yes-
PSMA2 5683 601.0931.10689Yes-
PSMB7 5695 480.9821.05257Yes-
PSMA1 5682 610.9961.052123Yes-
RPSA 3921 1561.3271.151152Yes-
PGD 5226 751.2011.106138Yes-
RPA2 6118 981.2501.15169Yes-
EIF6 3692 140.7001.013267Yes-
ACO2 50 501.0001.076191Yes-
RSL24D1 51187 361.3001.02059Yes-
CDC16 8881 250.9501.02080Yes-
PCNA 5111 50.5530.974294Yes-
PSMD3 5709 570.9861.106146Yes-
HNRNPK 3190 20.4880.938252Yes-
PSMD11 5717 1211.0951.106183Yes-
ACTB 60 1671.1531.151587Yes-
[ ANXA2 ] 302 10.2410.93888--
VCL 7414 1-0.3930.938140-Yes

Interactions (37)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
ACTB 60 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
PGD 5226 PSMD3 5709 pp -- int.I2D: YeastLow
PSMB7 5695 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
PSMB7 5695 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast
EIF6 3692 PGD 5226 pp -- int.I2D: YeastLow
HNRNPK 3190 RPSA 3921 pp -- int.I2D: IntAct_Rat
ANXA2 302 HNRNPK 3190 pp -- int.I2D: IntAct_Rat
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 VCL 7414 pp -- int.I2D: BIND
PSMA1 5682 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastMedium
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
PSMA1 5682 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Mouse, IntAct_Yeast, YeastLow, Krogan_Core, MINT_Yeast
ACTB 60 HNRNPK 3190 pp -- int.I2D: IntAct_Rat
ACTB 60 PSMB7 5695 pp -- int.I2D: BioGrid_Yeast
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACO2 50 PGD 5226 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD3 5709 pp -- int.I2D: BioGrid_Yeast, YeastLow
PSMA2 5683 VCL 7414 pp -- int.I2D: BIND
PSMD3 5709 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastHigh, INTEROLOG
PSMA2 5683 PSMB7 5695 pp -- int.Intact: MI:0914(association);
int.I2D: BCI, BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct, Krogan_Core, MINT_Yeast, YeastLow, IntAct_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
PSMA2 5683 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ANXA2 302 PCNA 5111 pp -- int.I2D: MINT, BioGrid;
int.Mint: MI:0915(physical association)
EIF6 3692 RSL24D1 51187 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 PSMA1 5682 pp -- int.I2D: BioGrid_Yeast
ANXA2 302 EIF6 3692 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 ANXA2 302 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
PSMA1 5682 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast, YeastLow
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
ANXA2 302 VCL 7414 pp -- int.I2D: BIND
HNRNPK 3190 VCL 7414 pp -- int.I2D: BIND
RPSA 3921 PCNA 5111 pp -- int.I2D: MINT, BioGrid;
int.Mint: MI:0915(physical association)
PSMA1 5682 PSMA2 5683 pp -- int.Intact: MI:0915(physical association), MI:0914(association);
int.I2D: BioGrid_Worm, BioGrid_Yeast, BIND_Worm, CE_DATA, HPRD, IntAct, IntAct_Mouse, IntAct_Yeast, INTEROLOG, MINT_Worm, BioGrid, IntAct_Fly, IntAct_Worm, Krogan_Core, MINT_Yeast, YeastHigh;
int.HPRD: yeast 2-hybrid
ACTB 60 CDC16 8881 pp -- int.I2D: YeastLow
ACO2 50 EIF6 3692 pp -- int.I2D: YeastLow
ACO2 50 PSMD11 5717 pp -- int.I2D: YeastLow

Related GO terms (291)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.18e-101.70e-066.20962265
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.86e-102.69e-066.10262270
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle2.62e-103.78e-066.02262274
GO:0000082G1/S transition of mitotic cell cycle3.15e-104.55e-065.234732149
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process3.92e-105.66e-065.92762379
GO:0006521regulation of cellular amino acid metabolic process3.38e-094.87e-056.32451750
GO:0000502proteasome complex7.26e-091.05e-046.11051758
GO:0005654nucleoplasm7.85e-091.13e-043.02611761082
GO:0000278mitotic cell cycle9.37e-091.35e-044.035848391
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.20e-081.73e-045.96851964
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.19e-083.16e-045.79852072
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.70e-083.89e-045.73952075
GO:0002474antigen processing and presentation of peptide antigen via MHC class I7.59e-081.10e-035.44552192
GO:0016032viral process1.06e-071.52e-033.585855534
GO:0016071mRNA metabolic process2.03e-072.93e-034.430631223
GO:0000209protein polyubiquitination2.43e-073.51e-035.110520116
GO:0070062extracellular vesicular exosome2.72e-073.92e-032.118131042400
GO:0016070RNA metabolic process3.71e-075.35e-034.283632247
GO:0042981regulation of apoptotic process8.74e-071.26e-024.739524150
GO:0005839proteasome core complex1.32e-061.90e-027.0613818
GO:0004298threonine-type endopeptidase activity1.56e-062.25e-026.9833819
GO:0034641cellular nitrogen compound metabolic process1.67e-062.41e-024.550520171
GO:0010467gene expression9.10e-061.31e-013.068759669
GO:0005829cytosol3.93e-055.66e-011.820111322496
GO:0019773proteasome core complex, alpha-subunit complex4.10e-055.91e-017.646248
GO:0005838proteasome regulatory particle9.64e-051.00e+007.0612712
GO:0043066negative regulation of apoptotic process1.34e-041.00e+003.240531424
GO:0022624proteasome accessory complex1.98e-041.00e+006.5592817
GO:0006298mismatch repair2.76e-041.00e+006.3242320
GO:0032201telomere maintenance via semi-conservative replication3.05e-041.00e+006.2542521
GO:0006297nucleotide-excision repair, DNA gap filling3.35e-041.00e+006.1872322
GO:0044281small molecule metabolic process4.02e-041.00e+002.2127581211
GO:0005730nucleolus4.22e-041.00e+001.9668691641
GO:0000722telomere maintenance via recombination4.34e-041.00e+006.0022525
GO:0006915apoptotic process4.68e-041.00e+002.852533555
GO:0005634nucleus4.75e-041.00e+001.192131364559
GO:0043022ribosome binding5.07e-041.00e+005.8912327
GO:0006271DNA strand elongation involved in DNA replication6.27e-041.00e+005.7392730
GO:0006284base-excision repair9.55e-041.00e+005.4372337
GO:0070527platelet aggregation1.01e-031.00e+005.3982238
GO:0032077positive regulation of deoxyribonuclease activity1.25e-031.00e+009.646111
GO:0000701purine-specific mismatch base pair DNA N-glycosylase activity1.25e-031.00e+009.646111
GO:0043626PCNA complex1.25e-031.00e+009.646111
GO:0030055cell-substrate junction1.25e-031.00e+009.646111
GO:0019521D-gluconate metabolic process1.25e-031.00e+009.646111
GO:0000054ribosomal subunit export from nucleus1.25e-031.00e+009.646111
GO:0006283transcription-coupled nucleotide-excision repair1.47e-031.00e+005.1232746
GO:0005515protein binding2.10e-031.00e+000.897141846024
GO:0000723telomere maintenance2.18e-031.00e+004.8392656
GO:0030337DNA polymerase processivity factor activity2.49e-031.00e+008.646112
GO:0006272leading strand elongation2.49e-031.00e+008.646122
GO:00515383 iron, 4 sulfur cluster binding2.49e-031.00e+008.646112
GO:0003994aconitate hydratase activity2.49e-031.00e+008.646112
GO:0006407rRNA export from nucleus2.49e-031.00e+008.646112
GO:0036035osteoclast development2.49e-031.00e+008.646122
GO:0072369regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter2.49e-031.00e+008.646112
GO:0070557PCNA-p21 complex2.49e-031.00e+008.646112
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.49e-031.00e+008.646112
GO:0019322pentose biosynthetic process2.49e-031.00e+008.646122
GO:0005055laminin receptor activity2.49e-031.00e+008.646112
GO:0006289nucleotide-excision repair3.19e-031.00e+004.55921168
GO:0003697single-stranded DNA binding3.19e-031.00e+004.5592568
GO:0010988regulation of low-density lipoprotein particle clearance3.74e-031.00e+008.061113
GO:0032139dinucleotide insertion or deletion binding3.74e-031.00e+008.061113
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity3.74e-031.00e+008.061113
GO:0044354macropinosome3.74e-031.00e+008.061113
GO:0001765membrane raft assembly3.74e-031.00e+008.061113
GO:0009051pentose-phosphate shunt, oxidative branch3.74e-031.00e+008.061123
GO:0006281DNA repair3.91e-031.00e+003.203318261
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.98e-031.00e+007.646114
GO:003068690S preribosome4.98e-031.00e+007.646114
GO:0019788NEDD8 ligase activity4.98e-031.00e+007.646114
GO:0045716positive regulation of low-density lipoprotein particle receptor biosynthetic process4.98e-031.00e+007.646114
GO:0031467Cul7-RING ubiquitin ligase complex4.98e-031.00e+007.646114
GO:0019834phospholipase A2 inhibitor activity4.98e-031.00e+007.646114
GO:0043234protein complex5.50e-031.00e+003.027318295
GO:0006928cellular component movement5.64e-031.00e+004.1382791
GO:0035749myelin sheath adaxonal region6.23e-031.00e+007.324125
GO:0031465Cul4B-RING E3 ubiquitin ligase complex6.23e-031.00e+007.324135
GO:0042256mature ribosome assembly6.23e-031.00e+007.324115
GO:0071229cellular response to acid chemical6.23e-031.00e+007.324115
GO:2000001regulation of DNA damage checkpoint6.23e-031.00e+007.324115
GO:0043023ribosomal large subunit binding6.23e-031.00e+007.324115
GO:0031461cullin-RING ubiquitin ligase complex6.23e-031.00e+007.324115
GO:0043248proteasome assembly6.23e-031.00e+007.324115
GO:0006102isocitrate metabolic process6.23e-031.00e+007.324115
GO:0030891VCB complex6.23e-031.00e+007.324125
GO:0006900membrane budding6.23e-031.00e+007.324115
GO:0000730DNA recombinase assembly6.23e-031.00e+007.324115
GO:0005638lamin filament6.23e-031.00e+007.324115
GO:0005813centrosome7.26e-031.00e+002.882314326
GO:0005663DNA replication factor C complex7.47e-031.00e+007.061116
GO:0006101citrate metabolic process7.47e-031.00e+007.061116
GO:0033993response to lipid7.47e-031.00e+007.061126
GO:0031466Cul5-RING ubiquitin ligase complex7.47e-031.00e+007.061116
GO:0030957Tat protein binding7.47e-031.00e+007.061136
GO:0032405MutLalpha complex binding7.47e-031.00e+007.061116
GO:0051099positive regulation of binding8.71e-031.00e+006.839117
GO:0000028ribosomal small subunit assembly8.71e-031.00e+006.839117
GO:0002162dystroglycan binding8.71e-031.00e+006.839117
GO:0031462Cul2-RING ubiquitin ligase complex8.71e-031.00e+006.839127
GO:0043297apical junction assembly8.71e-031.00e+006.839117
GO:0043596nuclear replication fork8.71e-031.00e+006.839117
GO:0034333adherens junction assembly8.71e-031.00e+006.839117
GO:0031340positive regulation of vesicle fusion8.71e-031.00e+006.839117
GO:0031464Cul4A-RING E3 ubiquitin ligase complex9.94e-031.00e+006.646128
GO:0070688MLL5-L complex9.94e-031.00e+006.646118
GO:0045294alpha-catenin binding9.94e-031.00e+006.646118
GO:0070182DNA polymerase binding9.94e-031.00e+006.646128
GO:0045116protein neddylation9.94e-031.00e+006.646128
GO:0005925focal adhesion9.96e-031.00e+002.715319366
GO:0000790nuclear chromatin1.11e-021.00e+003.63529129
GO:0090136epithelial cell-cell adhesion1.12e-021.00e+006.476119
GO:0006413translational initiation1.14e-021.00e+003.613217131
GO:0031982vesicle1.14e-021.00e+003.61329131
GO:0006098pentose-phosphate shunt1.24e-021.00e+006.3241410
GO:0010569regulation of double-strand break repair via homologous recombination1.24e-021.00e+006.3241110
GO:0007589body fluid secretion1.24e-021.00e+006.3241110
GO:0043220Schmidt-Lanterman incisure1.24e-021.00e+006.3241110
GO:0016020membrane1.33e-021.00e+001.5166901681
GO:0019985translesion synthesis1.36e-021.00e+006.1871211
GO:0044548S100 protein binding1.36e-021.00e+006.1871111
GO:0031571mitotic G1 DNA damage checkpoint1.36e-021.00e+006.1871411
GO:0051290protein heterotetramerization1.36e-021.00e+006.1871211
GO:0002009morphogenesis of an epithelium1.49e-021.00e+006.0611112
GO:0006275regulation of DNA replication1.49e-021.00e+006.0611212
GO:0042273ribosomal large subunit biogenesis1.61e-021.00e+005.9461413
GO:0005662DNA replication factor A complex1.61e-021.00e+005.9461113
GO:0005916fascia adherens1.61e-021.00e+005.9461113
GO:0030234enzyme regulator activity1.61e-021.00e+005.9461313
GO:0048260positive regulation of receptor-mediated endocytosis1.61e-021.00e+005.9461213
GO:0035267NuA4 histone acetyltransferase complex1.73e-021.00e+005.8391414
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.76e-021.00e+003.28027165
GO:0042176regulation of protein catabolic process1.98e-021.00e+005.6461316
GO:0050998nitric-oxide synthase binding1.98e-021.00e+005.6461116
GO:0002102podosome1.98e-021.00e+005.6461216
GO:0031625ubiquitin protein ligase binding2.04e-021.00e+003.170214178
GO:0042730fibrinolysis2.22e-021.00e+005.4761118
GO:0035861site of double-strand break2.22e-021.00e+005.4761118
GO:0034394protein localization to cell surface2.22e-021.00e+005.4761118
GO:0007088regulation of mitosis2.22e-021.00e+005.4761118
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process2.35e-021.00e+005.3981119
GO:0048863stem cell differentiation2.35e-021.00e+005.3981119
GO:0072661protein targeting to plasma membrane2.35e-021.00e+005.3981119
GO:0019897extrinsic component of plasma membrane2.47e-021.00e+005.3241220
GO:0005680anaphase-promoting complex2.47e-021.00e+005.3241420
GO:0043034costamere2.47e-021.00e+005.3241120
GO:0000718nucleotide-excision repair, DNA damage removal2.59e-021.00e+005.2541421
GO:0000083regulation of transcription involved in G1/S transition of mitotic cell cycle2.71e-021.00e+005.1871222
GO:0046686response to cadmium ion2.71e-021.00e+005.1871222
GO:0030863cortical cytoskeleton2.71e-021.00e+005.1871122
GO:0036464cytoplasmic ribonucleoprotein granule2.71e-021.00e+005.1871422
GO:0031463Cul3-RING ubiquitin ligase complex2.83e-021.00e+005.1231323
GO:0043236laminin binding2.83e-021.00e+005.1231123
GO:0006513protein monoubiquitination2.83e-021.00e+005.1231123
GO:0043044ATP-dependent chromatin remodeling2.83e-021.00e+005.1231423
GO:0005844polysome2.83e-021.00e+005.1231423
GO:0045296cadherin binding2.95e-021.00e+005.0611124
GO:0070979protein K11-linked ubiquitination3.20e-021.00e+004.9461626
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia3.20e-021.00e+004.9461326
GO:0050661NADP binding3.32e-021.00e+004.8911227
GO:0031492nucleosomal DNA binding3.32e-021.00e+004.8911427
GO:0006099tricarboxylic acid cycle3.44e-021.00e+004.8391428
GO:0019894kinesin binding3.44e-021.00e+004.8391128
GO:0019005SCF ubiquitin ligase complex3.56e-021.00e+004.7881129
GO:0005913cell-cell adherens junction3.56e-021.00e+004.7881129
GO:0030032lamellipodium assembly3.56e-021.00e+004.7881229
GO:0042254ribosome biogenesis3.68e-021.00e+004.7391130
GO:0005544calcium-dependent phospholipid binding3.68e-021.00e+004.7391230
GO:0007094mitotic spindle assembly checkpoint3.80e-021.00e+004.6921431
GO:0030971receptor tyrosine kinase binding4.04e-021.00e+004.6021233
GO:0001895retina homeostasis4.16e-021.00e+004.5591134
GO:0005876spindle microtubule4.16e-021.00e+004.5591234
GO:0005912adherens junction4.28e-021.00e+004.5171235
GO:00515394 iron, 4 sulfur cluster binding4.28e-021.00e+004.5171335
GO:0034332adherens junction organization4.40e-021.00e+004.4761136
GO:0030199collagen fibril organization4.52e-021.00e+004.4371137
GO:0051084'de novo' posttranslational protein folding4.52e-021.00e+004.4371437
GO:0000781chromosome, telomeric region4.76e-021.00e+004.3611339
GO:0005546phosphatidylinositol-4,5-bisphosphate binding4.76e-021.00e+004.3611239
GO:0022627cytosolic small ribosomal subunit4.76e-021.00e+004.3611439
GO:0005856cytoskeleton5.02e-021.00e+002.461212291
GO:0021762substantia nigra development5.35e-021.00e+004.1871244
GO:0048146positive regulation of fibroblast proliferation5.35e-021.00e+004.1871244
GO:0008092cytoskeletal protein binding5.71e-021.00e+004.0921147
GO:0005811lipid particle5.71e-021.00e+004.0921247
GO:0003743translation initiation factor activity5.95e-021.00e+004.0311849
GO:0003684damaged DNA binding5.95e-021.00e+004.0311749
GO:0006091generation of precursor metabolites and energy6.06e-021.00e+004.0021350
GO:0008283cell proliferation6.21e-021.00e+002.289214328
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding6.42e-021.00e+003.9181553
GO:0045216cell-cell junction organization6.53e-021.00e+003.8911254
GO:0000932cytoplasmic mRNA processing body6.53e-021.00e+003.8911354
GO:0000724double-strand break repair via homologous recombination6.65e-021.00e+003.8651355
GO:0003723RNA binding6.68e-021.00e+002.228220342
GO:0048306calcium-dependent protein binding6.77e-021.00e+003.8391156
GO:0006396RNA processing7.12e-021.00e+003.7641159
GO:0042995cell projection7.23e-021.00e+003.7391660
GO:0008013beta-catenin binding7.23e-021.00e+003.7391360
GO:0030855epithelial cell differentiation7.35e-021.00e+003.7151461
GO:0006302double-strand break repair7.47e-021.00e+003.6921462
GO:0019903protein phosphatase binding7.47e-021.00e+003.6921462
GO:0007155cell adhesion7.63e-021.00e+002.11926369
GO:0005604basement membrane7.93e-021.00e+003.6021166
GO:0034329cell junction assembly8.16e-021.00e+003.5591168
GO:0042383sarcolemma8.50e-021.00e+003.4961371
GO:0043086negative regulation of catalytic activity8.62e-021.00e+003.4761272
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis8.85e-021.00e+003.4371674
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process8.96e-021.00e+003.4171275
GO:0017137Rab GTPase binding9.08e-021.00e+003.3981276
GO:0031902late endosome membrane9.19e-021.00e+003.3791177
GO:0030336negative regulation of cell migration9.30e-021.00e+003.3611178
GO:0071013catalytic step 2 spliceosome9.30e-021.00e+003.3611478
GO:0001726ruffle9.53e-021.00e+003.3241480
GO:0019083viral transcription9.65e-021.00e+003.30611081
GO:0007160cell-matrix adhesion9.76e-021.00e+003.2891382
GO:0002576platelet degranulation9.76e-021.00e+003.2891482
GO:0047485protein N-terminus binding1.02e-011.00e+003.2201586
GO:0006415translational termination1.03e-011.00e+003.20311087
GO:0006936muscle contraction1.03e-011.00e+003.2031287
GO:0016605PML body1.04e-011.00e+003.1871388
GO:0042470melanosome1.08e-011.00e+003.1381991
GO:0005200structural constituent of cytoskeleton1.08e-011.00e+003.1381891
GO:0007596blood coagulation1.09e-011.00e+001.816218455
GO:0071456cellular response to hypoxia1.09e-011.00e+003.1231692
GO:0006414translational elongation1.10e-011.00e+003.10711393
GO:0044267cellular protein metabolic process1.17e-011.00e+001.757229474
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.22e-011.00e+002.946110104
GO:0001934positive regulation of protein phosphorylation1.22e-011.00e+002.94616104
GO:0005938cell cortex1.22e-011.00e+002.94613104
GO:0014069postsynaptic density1.23e-011.00e+002.93213105
GO:0005506iron ion binding1.23e-011.00e+002.93214105
GO:0030496midbody1.27e-011.00e+002.89115108
GO:0015630microtubule cytoskeleton1.29e-011.00e+002.86514110
GO:0072562blood microparticle1.30e-011.00e+002.85213111
GO:0030529ribonucleoprotein complex1.31e-011.00e+002.83918112
GO:0005819spindle1.31e-011.00e+002.83917112
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.33e-011.00e+002.813111114
GO:0019058viral life cycle1.34e-011.00e+002.801113115
GO:0044237cellular metabolic process1.36e-011.00e+002.77615117
GO:0006325chromatin organization1.38e-011.00e+002.76415118
GO:0007219Notch signaling pathway1.40e-011.00e+002.73915120
GO:0006260DNA replication1.41e-011.00e+002.72719121
GO:0044822poly(A) RNA binding1.41e-011.00e+001.1873491056
GO:0009615response to virus1.46e-011.00e+002.66915126
GO:0006511ubiquitin-dependent protein catabolic process1.46e-011.00e+002.66915126
GO:0005911cell-cell junction1.57e-011.00e+002.55914136
GO:0003735structural constituent of ribosome1.58e-011.00e+002.548110137
GO:0007507heart development1.60e-011.00e+002.52717139
GO:0006457protein folding1.64e-011.00e+002.48617143
GO:0005737cytoplasm1.66e-011.00e+000.57471103767
GO:0061024membrane organization1.66e-011.00e+002.46617145
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription1.68e-011.00e+002.44613147
GO:0005198structural molecule activity1.72e-011.00e+002.41715150
GO:0005769early endosome1.74e-011.00e+002.39812152
GO:0031012extracellular matrix1.76e-011.00e+002.37912154
GO:0045121membrane raft1.78e-011.00e+002.36118156
GO:0000398mRNA splicing, via spliceosome1.86e-011.00e+002.28918164
GO:0030424axon1.88e-011.00e+002.27114166
GO:0005768endosome1.91e-011.00e+002.24516169
GO:0015629actin cytoskeleton1.99e-011.00e+002.17913177
GO:0032403protein complex binding2.05e-011.00e+002.130110183
GO:0001525angiogenesis2.13e-011.00e+002.06914191
GO:0005765lysosomal membrane2.25e-011.00e+001.98115203
GO:0030168platelet activation2.27e-011.00e+001.967110205
GO:0007067mitotic nuclear division2.49e-011.00e+001.820114227
GO:0005759mitochondrial matrix2.49e-011.00e+001.813114228
GO:0008380RNA splicing2.49e-011.00e+001.813111228
GO:0006412translation2.51e-011.00e+001.801120230
GO:0005975carbohydrate metabolic process2.73e-011.00e+001.66319253
GO:0004842ubiquitin-protein transferase activity2.75e-011.00e+001.65216255
GO:0003779actin binding2.85e-011.00e+001.591112266
GO:0019899enzyme binding2.95e-011.00e+001.532112277
GO:0016567protein ubiquitination3.11e-011.00e+001.44215295
GO:0019901protein kinase binding3.30e-011.00e+001.338121317
GO:0007411axon guidance3.32e-011.00e+001.329113319
GO:0005615extracellular space3.38e-011.00e+000.744217957
GO:0009986cell surface3.99e-011.00e+000.995111402
GO:0055114oxidation-reduction process4.13e-011.00e+000.932112420
GO:0042802identical protein binding4.59e-011.00e+000.727120484
GO:0048471perinuclear region of cytoplasm4.72e-011.00e+000.675113502
GO:0005509calcium ion binding4.91e-011.00e+000.59415531
GO:0045087innate immune response5.32e-011.00e+000.427124596
GO:0045944positive regulation of transcription from RNA polymerase II promoter6.37e-011.00e+000.022119789
GO:0005886plasma membrane6.50e-011.00e+00-0.1033452582
GO:0007165signal transduction6.90e-011.00e+00-0.179124907
GO:0005576extracellular region7.04e-011.00e+00-0.23314942
GO:0008270zinc ion binding7.25e-011.00e+00-0.315112997
GO:0005739mitochondrion7.25e-011.00e+00-0.317128998
GO:0005524ATP binding8.17e-011.00e+00-0.6961601298
GO:0006351transcription, DNA-templated8.51e-011.00e+00-0.8521311446