int-snw-2027

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
wolf-screen-ratio-mammosphere-adherent 0.968 8.21e-17 1.18e-03 2.34e-02
wolf-screen-ratio-mammosphere-adherent-int-snw-2027 subnetwork

Genes (10)

Gene Symbol Entrez Gene ID Frequency wolf-screen-ratio-mammosphere-adherent gene score Best subnetwork score Degree wolf adherent-list Hits GI wolf mammosphere no adherent-list Hits GI
RPA2 6118 981.2501.15169Yes-
CAD 790 170.8071.007333--
EEF2 1938 270.8901.043301Yes-
RBX1 9978 971.1851.151139Yes-
[ ENO3 ] 2027 1-0.1030.96873--
NAA10 8260 50.6680.983136Yes-
PSMD11 5717 1211.0951.106183Yes-
ACTB 60 1671.1531.151587Yes-
RPSA 3921 1561.3271.151152Yes-
PGD 5226 751.2011.106138Yes-

Interactions (17)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CAD 790 RPSA 3921 pp -- int.I2D: IntAct_Yeast
EEF2 1938 PGD 5226 pp -- int.I2D: BioGrid_Yeast
PGD 5226 PSMD11 5717 pp -- int.I2D: YeastLow
EEF2 1938 ENO3 2027 pp -- int.I2D: YeastLow
ACTB 60 NAA10 8260 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 PSMD11 5717 pp -- int.I2D: IntAct_Yeast
CAD 790 ENO3 2027 pp -- int.I2D: BioGrid_Yeast
ACTB 60 ENO3 2027 pp -- int.I2D: YeastLow
ACTB 60 RPSA 3921 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct_Yeast, IntAct
ACTB 60 RBX1 9978 pp -- int.I2D: BioGrid_Yeast
CAD 790 NAA10 8260 pp -- int.I2D: IntAct_Yeast
ACTB 60 CAD 790 pp -- int.I2D: IntAct_Yeast
ACTB 60 RPA2 6118 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
ACTB 60 EEF2 1938 pp -- int.I2D: YeastLow, IntAct_Yeast
ENO3 2027 NAA10 8260 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastLow
ACTB 60 PSMD11 5717 pp -- int.I2D: BioGrid_Yeast
RPSA 3921 NAA10 8260 pp -- int.I2D: IntAct_Yeast

Related GO terms (213)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0005829cytosol2.57e-053.71e-012.20981322496
GO:0043022ribosome binding1.50e-041.00e+006.7392327
GO:0070062extracellular vesicular exosome2.63e-041.00e+002.07371042400
GO:0016020membrane3.44e-041.00e+002.3646901681
GO:0004151dihydroorotase activity6.93e-041.00e+0010.494111
GO:0019521D-gluconate metabolic process6.93e-041.00e+0010.494111
GO:0004070aspartate carbamoyltransferase activity6.93e-041.00e+0010.494111
GO:0004088carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity6.93e-041.00e+0010.494111
GO:0070335aspartate binding6.93e-041.00e+0010.494111
GO:0000461endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)1.39e-031.00e+009.494112
GO:0019322pentose biosynthetic process1.39e-031.00e+009.494122
GO:0005055laminin receptor activity1.39e-031.00e+009.494112
GO:0006407rRNA export from nucleus1.39e-031.00e+009.494112
GO:0070409carbamoyl phosphate biosynthetic process1.39e-031.00e+009.494112
GO:0006414translational elongation1.79e-031.00e+004.95521393
GO:0009051pentose-phosphate shunt, oxidative branch2.08e-031.00e+008.909123
GO:0004616phosphogluconate dehydrogenase (decarboxylating) activity2.08e-031.00e+008.909113
GO:0000015phosphopyruvate hydratase complex2.08e-031.00e+008.909123
GO:0044205'de novo' UMP biosynthetic process2.08e-031.00e+008.909113
GO:0006207'de novo' pyrimidine nucleobase biosynthetic process2.08e-031.00e+008.909113
GO:0004634phosphopyruvate hydratase activity2.08e-031.00e+008.909123
GO:0030529ribonucleoprotein complex2.58e-031.00e+004.68728112
GO:0000447endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.77e-031.00e+008.494114
GO:003068690S preribosome2.77e-031.00e+008.494114
GO:0006543glutamine catabolic process2.77e-031.00e+008.494114
GO:0031467Cul7-RING ubiquitin ligase complex2.77e-031.00e+008.494114
GO:0019788NEDD8 ligase activity2.77e-031.00e+008.494114
GO:0051414response to cortisol3.46e-031.00e+008.172115
GO:0031465Cul4B-RING E3 ubiquitin ligase complex3.46e-031.00e+008.172135
GO:0031461cullin-RING ubiquitin ligase complex3.46e-031.00e+008.172115
GO:0043248proteasome assembly3.46e-031.00e+008.172115
GO:0006323DNA packaging3.46e-031.00e+008.172115
GO:0030891VCB complex3.46e-031.00e+008.172125
GO:0004596peptide alpha-N-acetyltransferase activity3.46e-031.00e+008.172115
GO:0000730DNA recombinase assembly3.46e-031.00e+008.172115
GO:2000001regulation of DNA damage checkpoint3.46e-031.00e+008.172115
GO:0031415NatA complex3.46e-031.00e+008.172115
GO:0044267cellular protein metabolic process3.56e-031.00e+003.190329474
GO:0006474N-terminal protein amino acid acetylation4.15e-031.00e+007.909116
GO:0030957Tat protein binding4.15e-031.00e+007.909136
GO:0046134pyrimidine nucleoside biosynthetic process4.15e-031.00e+007.909116
GO:0031466Cul5-RING ubiquitin ligase complex4.15e-031.00e+007.909116
GO:0000082G1/S transition of mitotic cell cycle4.52e-031.00e+004.275232149
GO:0005654nucleoplasm4.58e-031.00e+002.4154761082
GO:0000028ribosomal small subunit assembly4.84e-031.00e+007.687117
GO:0006475internal protein amino acid acetylation4.84e-031.00e+007.687117
GO:0031462Cul2-RING ubiquitin ligase complex4.84e-031.00e+007.687127
GO:0016032viral process4.98e-031.00e+003.018355534
GO:0031464Cul4A-RING E3 ubiquitin ligase complex5.53e-031.00e+007.494128
GO:0008080N-acetyltransferase activity5.53e-031.00e+007.494118
GO:0070688MLL5-L complex5.53e-031.00e+007.494118
GO:0045116protein neddylation5.53e-031.00e+007.494128
GO:0006228UTP biosynthetic process6.22e-031.00e+007.324119
GO:0014075response to amine6.22e-031.00e+007.324119
GO:0031000response to caffeine6.22e-031.00e+007.324129
GO:0008494translation activator activity6.22e-031.00e+007.324119
GO:0031625ubiquitin protein ligase binding6.39e-031.00e+004.018214178
GO:0044281small molecule metabolic process6.88e-031.00e+002.2524581211
GO:0006098pentose-phosphate shunt6.91e-031.00e+007.1721410
GO:0016407acetyltransferase activity6.91e-031.00e+007.1721110
GO:0010569regulation of double-strand break repair via homologous recombination6.91e-031.00e+007.1721110
GO:0031571mitotic G1 DNA damage checkpoint7.60e-031.00e+007.0351411
GO:0043403skeletal muscle tissue regeneration7.60e-031.00e+007.0351211
GO:0005838proteasome regulatory particle8.29e-031.00e+006.9091712
GO:0005662DNA replication factor A complex8.98e-031.00e+006.7941113
GO:0010467gene expression9.33e-031.00e+002.693359669
GO:0035267NuA4 histone acetyltransferase complex9.67e-031.00e+006.6871414
GO:0016071mRNA metabolic process9.87e-031.00e+003.693231223
GO:0006412translation1.05e-021.00e+003.649220230
GO:0050998nitric-oxide synthase binding1.10e-021.00e+006.4941116
GO:0006541glutamine metabolic process1.17e-021.00e+006.4071117
GO:0003746translation elongation factor activity1.17e-021.00e+006.4071317
GO:0022624proteasome accessory complex1.17e-021.00e+006.4071817
GO:0016070RNA metabolic process1.20e-021.00e+003.546232247
GO:0035861site of double-strand break1.24e-021.00e+006.3241118
GO:0017144drug metabolic process1.24e-021.00e+006.3241118
GO:0005975carbohydrate metabolic process1.26e-021.00e+003.51129253
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process1.31e-021.00e+006.2461119
GO:0048863stem cell differentiation1.31e-021.00e+006.2461119
GO:0006281DNA repair1.33e-021.00e+003.466218261
GO:0006298mismatch repair1.38e-021.00e+006.1721320
GO:0005634nucleus1.44e-021.00e+001.14771364559
GO:0071364cellular response to epidermal growth factor stimulus1.45e-021.00e+006.1021121
GO:0032201telomere maintenance via semi-conservative replication1.45e-021.00e+006.1021521
GO:0000718nucleotide-excision repair, DNA damage removal1.45e-021.00e+006.1021421
GO:0019899enzyme binding1.49e-021.00e+003.380212277
GO:0006206pyrimidine nucleobase metabolic process1.52e-021.00e+006.0351222
GO:0006297nucleotide-excision repair, DNA gap filling1.52e-021.00e+006.0351322
GO:0033574response to testosterone1.52e-021.00e+006.0351222
GO:0030863cortical cytoskeleton1.52e-021.00e+006.0351122
GO:0036464cytoplasmic ribonucleoprotein granule1.52e-021.00e+006.0351422
GO:0043044ATP-dependent chromatin remodeling1.58e-021.00e+005.9711423
GO:0005844polysome1.58e-021.00e+005.9711423
GO:0031463Cul3-RING ubiquitin ligase complex1.58e-021.00e+005.9711323
GO:0043236laminin binding1.58e-021.00e+005.9711123
GO:0006513protein monoubiquitination1.58e-021.00e+005.9711123
GO:0043234protein complex1.68e-021.00e+003.290218295
GO:0000722telomere maintenance via recombination1.72e-021.00e+005.8501525
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia1.79e-021.00e+005.7941326
GO:0050661NADP binding1.86e-021.00e+005.7391227
GO:0031492nucleosomal DNA binding1.86e-021.00e+005.7391427
GO:0019901protein kinase binding1.93e-021.00e+003.186221317
GO:0019894kinesin binding1.93e-021.00e+005.6871128
GO:0019005SCF ubiquitin ligase complex1.99e-021.00e+005.6361129
GO:0006271DNA strand elongation involved in DNA replication2.06e-021.00e+005.5871730
GO:0001895retina homeostasis2.33e-021.00e+005.4071134
GO:0034332adherens junction organization2.47e-021.00e+005.3241136
GO:0018107peptidyl-threonine phosphorylation2.54e-021.00e+005.2851437
GO:0051084'de novo' posttranslational protein folding2.54e-021.00e+005.2851437
GO:0006284base-excision repair2.54e-021.00e+005.2851337
GO:0006096glycolytic process2.60e-021.00e+005.2461438
GO:0070527platelet aggregation2.60e-021.00e+005.2461238
GO:0022627cytosolic small ribosomal subunit2.67e-021.00e+005.2091439
GO:0000781chromosome, telomeric region2.67e-021.00e+005.2091339
GO:0007595lactation2.67e-021.00e+005.2091239
GO:0043195terminal bouton2.81e-021.00e+005.1371141
GO:0000278mitotic cell cycle2.86e-021.00e+002.883248391
GO:0006094gluconeogenesis2.94e-021.00e+005.0681543
GO:0021762substantia nigra development3.01e-021.00e+005.0351244
GO:0045727positive regulation of translation3.01e-021.00e+005.0351344
GO:0006283transcription-coupled nucleotide-excision repair3.14e-021.00e+004.9711746
GO:0035690cellular response to drug3.35e-021.00e+004.8791249
GO:0003684damaged DNA binding3.35e-021.00e+004.8791749
GO:0006521regulation of cellular amino acid metabolic process3.41e-021.00e+004.85011750
GO:0031100organ regeneration3.41e-021.00e+004.8501450
GO:0000980RNA polymerase II distal enhancer sequence-specific DNA binding3.62e-021.00e+004.7661553
GO:0002244hematopoietic progenitor cell differentiation3.68e-021.00e+004.7391154
GO:0045216cell-cell junction organization3.68e-021.00e+004.7391254
GO:0000724double-strand break repair via homologous recombination3.75e-021.00e+004.7131355
GO:0000723telomere maintenance3.82e-021.00e+004.6871656
GO:0000502proteasome complex3.95e-021.00e+004.63611758
GO:0042995cell projection4.08e-021.00e+004.5871660
GO:0019903protein phosphatase binding4.22e-021.00e+004.5401462
GO:0006302double-strand break repair4.22e-021.00e+004.5401462
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest4.35e-021.00e+004.49411964
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle4.42e-021.00e+004.47212265
GO:0006289nucleotide-excision repair4.62e-021.00e+004.40711168
GO:0034329cell junction assembly4.62e-021.00e+004.4071168
GO:0003697single-stranded DNA binding4.62e-021.00e+004.4071568
GO:0055086nucleobase-containing small molecule metabolic process4.75e-021.00e+004.3651270
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle4.75e-021.00e+004.36512270
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent4.88e-021.00e+004.32412072
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis5.02e-021.00e+004.2851674
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle5.02e-021.00e+004.28512274
GO:0043161proteasome-mediated ubiquitin-dependent protein catabolic process5.08e-021.00e+004.2651275
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I5.08e-021.00e+004.26512075
GO:0001889liver development5.21e-021.00e+004.2271477
GO:0007565female pregnancy5.28e-021.00e+004.2091178
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process5.35e-021.00e+004.19012379
GO:0019083viral transcription5.48e-021.00e+004.15411081
GO:0047485protein N-terminus binding5.81e-021.00e+004.0681586
GO:0006415translational termination5.87e-021.00e+004.05111087
GO:0016605PML body5.94e-021.00e+004.0351388
GO:0016363nuclear matrix6.14e-021.00e+003.98611291
GO:0006928cellular component movement6.14e-021.00e+003.9861791
GO:0005200structural constituent of cytoskeleton6.14e-021.00e+003.9861891
GO:0071456cellular response to hypoxia6.20e-021.00e+003.9711692
GO:0002474antigen processing and presentation of peptide antigen via MHC class I6.20e-021.00e+003.97112192
GO:0005515protein binding6.90e-021.00e+000.74571846024
GO:0006614SRP-dependent cotranslational protein targeting to membrane6.98e-021.00e+003.794110104
GO:0014069postsynaptic density7.05e-021.00e+003.78013105
GO:0072562blood microparticle7.44e-021.00e+003.70013111
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay7.63e-021.00e+003.661111114
GO:0019058viral life cycle7.70e-021.00e+003.649113115
GO:0000209protein polyubiquitination7.76e-021.00e+003.636120116
GO:0007568aging7.82e-021.00e+003.62413117
GO:0006006glucose metabolic process7.89e-021.00e+003.61217118
GO:0006325chromatin organization7.89e-021.00e+003.61215118
GO:0007219Notch signaling pathway8.02e-021.00e+003.58715120
GO:0006260DNA replication8.08e-021.00e+003.57519121
GO:0006511ubiquitin-dependent protein catabolic process8.40e-021.00e+003.51715126
GO:0000790nuclear chromatin8.60e-021.00e+003.48319129
GO:0006413translational initiation8.72e-021.00e+003.461117131
GO:0003735structural constituent of ribosome9.11e-021.00e+003.396110137
GO:0007507heart development9.23e-021.00e+003.37517139
GO:0006457protein folding9.49e-021.00e+003.33417143
GO:0061024membrane organization9.61e-021.00e+003.31417145
GO:0010628positive regulation of gene expression9.68e-021.00e+003.30415146
GO:0042981regulation of apoptotic process9.93e-021.00e+003.265124150
GO:0046777protein autophosphorylation1.04e-011.00e+003.19017158
GO:0000287magnesium ion binding1.08e-011.00e+003.13714164
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding1.09e-011.00e+003.12817165
GO:0030424axon1.09e-011.00e+003.11914166
GO:0034641cellular nitrogen compound metabolic process1.12e-011.00e+003.076120171
GO:0004672protein kinase activity1.16e-011.00e+003.02716177
GO:0032403protein complex binding1.20e-011.00e+002.978110183
GO:0003924GTPase activity1.29e-011.00e+002.872112197
GO:0005622intracellular1.35e-011.00e+002.80116207
GO:0006184GTP catabolic process1.39e-011.00e+002.753112214
GO:0005615extracellular space1.39e-011.00e+001.592217957
GO:0008270zinc ion binding1.49e-011.00e+001.533212997
GO:0043025neuronal cell body1.57e-011.00e+002.55819245
GO:0044822poly(A) RNA binding1.63e-011.00e+001.4502491056
GO:0004842ubiquitin-protein transferase activity1.63e-011.00e+002.50016255
GO:0042493response to drug1.80e-011.00e+002.344113284
GO:0005856cytoskeleton1.84e-011.00e+002.309112291
GO:0016567protein ubiquitination1.87e-011.00e+002.29015295
GO:0005525GTP binding1.95e-011.00e+002.218112310
GO:0007411axon guidance2.00e-011.00e+002.177113319
GO:0005524ATP binding2.25e-011.00e+001.1522601298
GO:0005925focal adhesion2.27e-011.00e+001.978119366
GO:0007155cell adhesion2.28e-011.00e+001.96716369
GO:0046982protein heterodimerization activity2.34e-011.00e+001.924113380
GO:0005737cytoplasm2.51e-011.00e+000.61541103767
GO:0055114oxidation-reduction process2.56e-011.00e+001.780112420
GO:0043066negative regulation of apoptotic process2.58e-011.00e+001.766131424
GO:0007596blood coagulation2.74e-011.00e+001.664118455
GO:0042802identical protein binding2.89e-011.00e+001.575120484
GO:0005730nucleolus3.18e-011.00e+000.8142691641
GO:0006915apoptotic process3.25e-011.00e+001.378133555
GO:0042803protein homodimerization activity3.44e-011.00e+001.277112595
GO:0045087innate immune response3.44e-011.00e+001.275124596
GO:0005886plasma membrane5.58e-011.00e+000.1602452582