meta-reg-snw-988

Interacting subnets

Subnetwork	Dataset	Score	p-value 1	p-value 2	p-value 3	Size	Highlighted genes
int-snw-10296	tai-screen-luciferase	6.413	3.70e-138	2.79e-07	2.32e-03	18	15
reg-snw-988	tai-screen-luciferase	5.672	6.20e-37	3.20e-06	7.14e-06	5	3
int-snw-51382	tai-screen-luciferase	7.286	3.65e-186	4.21e-10	1.27e-04	13	12
int-snw-51741	tai-screen-luciferase	6.174	2.67e-126	1.32e-06	4.54e-03	24	19

tai-screen-luciferase-meta-reg-snw-988 subnetwork

Genes (32)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	List-Gonzales GI	Tai-Hits
MAPK8	5599	28	-4.403	6.468	153	-	-
COPA	1314	48	-9.395	5.672	340	Yes	Yes
RNF20	56254	28	-4.564	6.174	18	-	-
HSF1	3297	46	-4.179	5.027	209	-	Yes
SRC	6714	28	-2.806	6.174	419	Yes	-
COPB2	9276	48	-13.168	9.063	41	Yes	Yes
CKAP5	9793	46	-7.214	5.672	130	Yes	Yes
EIF2S2	8894	31	-4.320	5.672	103	Yes	-
CDC42	998	44	-6.960	4.707	276	Yes	Yes
MAEA	10296	13	-2.793	6.413	43	-	-
ARL1	400	18	-4.142	8.046	110	-	Yes
RPS11	6205	44	-6.588	7.555	175	Yes	-
RPS6	6194	44	-5.603	8.046	217	Yes	-
TLK2	11011	21	-4.011	5.672	14	-	-
RAN	5901	38	-3.809	4.325	258	Yes	Yes
UBB	7314	30	-4.289	6.428	147	-	-
COPB1	1315	39	-6.221	9.063	118	Yes	Yes
RPS13	6207	43	-6.589	7.555	174	Yes	-
CDC5L	988	34	-3.419	5.672	155	-	-
RPS24	6229	46	-7.034	8.389	217	Yes	-
RPS9	6203	45	-7.127	7.555	140	Yes	-
TCERG1	10915	28	-3.808	6.174	58	Yes	-
RPS4X	6191	44	-6.747	7.555	263	Yes	-
COPZ1	22818	48	-8.301	9.063	13	Yes	Yes
ATP6V1D	51382	30	-4.131	7.286	149	-	-
RPS15A	6210	36	-5.413	7.555	177	Yes	-
RPS27A	6233	45	-5.631	8.389	344	Yes	-
WWOX	51741	28	-2.448	6.174	38	-	-
SKP1	6500	26	-3.750	6.413	203	-	-
NFKBIB	4793	28	-3.978	6.174	78	-	-
ARCN1	372	48	-8.232	9.063	118	Yes	Yes
RPS26	6231	43	-7.478	8.046	60	Yes	-

Interactions (65)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
CDC42	998	RPS27A	6233	pp	--	int.I2D: SOURAV_MAPK_HIGH
RPS27A	6233	SKP1	6500	pp	--	int.I2D: BioGrid_Yeast, YeastLow
ARCN1	372	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
RPS11	6205	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
TCERG1	10915	WWOX	51741	pp	--	int.I2D: BioGrid, MINT, Pawson1; int.Mint: MI:0915(physical association)
EIF2S2	8894	ATP6V1D	51382	pp	--	int.I2D: YeastLow
RPS6	6194	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
SRC	6714	CKAP5	9793	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPS6	6194	RPS26	6231	pp	--	int.I2D: YeastLow
ARCN1	372	RAN	5901	pp	--	int.I2D: YeastLow
CDC42	998	UBB	7314	pp	--	int.I2D: SOURAV_MAPK_HIGH
NFKBIB	4793	UBB	7314	pp	--	int.Intact: MI:0915(physical association); int.I2D: IntAct
RPS9	6203	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS9	6203	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
SKP1	6500	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast
RAN	5901	RPS11	6205	pp	--	int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPS9	6203	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS9	6203	pp	--	int.I2D: BioGrid_Yeast
UBB	7314	WWOX	51741	pp	--	int.I2D: BCI, HPRD; int.HPRD: in vivo
UBB	7314	RNF20	56254	pp	--	int.Intact: MI:0220(ubiquitination reaction); int.I2D: IntAct
RPS11	6205	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS11	6205	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
SRC	6714	WWOX	51741	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo
MAEA	10296	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
ARL1	400	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
RPS27A	6233	UBB	7314	pp	--	int.I2D: BIND
RPS4X	6191	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
ARL1	400	COPA	1314	pp	--	int.I2D: BioGrid_Yeast
RPS4X	6191	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS6	6194	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
RPS13	6207	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
RPS6	6194	RPS27A	6233	pp	--	int.I2D: YeastLow
RPS6	6194	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	COPB1	1315	pp	--	int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
RPS24	6229	ATP6V1D	51382	pp	--	int.I2D: BioGrid_Yeast
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
HSF1	3297	MAPK8	5599	pp	--	int.I2D: HPRD, INNATEDB; int.HPRD: in vitro, in vivo
COPA	1314	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
NFKBIB	4793	SKP1	6500	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vitro
COPA	1314	COPB2	9276	pp	--	int.I2D: BioGrid, HPRD, BCI; int.HPRD: in vivo
COPB1	1315	COPZ1	22818	pp	--	int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium; int.DIP: MI:0915(physical association)
COPA	1314	ATP6V1D	51382	pp	--	int.I2D: YeastLow
RPS4X	6191	RPS13	6207	pp	--	int.I2D: BioGrid_Yeast
RPS15A	6210	RPS24	6229	pp	--	int.I2D: BioGrid_Yeast
CDC5L	988	TLK2	11011	pd	>	reg.ITFP.txt: no annot
RPS13	6207	RPS15A	6210	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	ARL1	400	pp	--	int.I2D: BioGrid_Yeast
ARL1	400	RPS6	6194	pp	--	int.I2D: BioGrid_Yeast
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	EIF2S2	8894	pd	>	reg.ITFP.txt: no annot
COPB1	1315	COPB2	9276	pp	--	int.I2D: BioGrid
ARCN1	372	COPB1	1315	pp	--	int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS; int.HPRD: in vivo
RPS9	6203	RPS11	6205	pp	--	int.I2D: BioGrid_Yeast
ARCN1	372	COPA	1314	pp	--	int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core; int.HPRD: in vivo
RPS4X	6191	RPS6	6194	pp	--	int.I2D: BioGrid_Yeast
COPA	1314	RPS27A	6233	pp	--	int.I2D: YeastLow
MAPK8	5599	WWOX	51741	pp	--	int.I2D: MINT, HPRD; int.Mint: MI:0915(physical association); int.HPRD: in vivo, yeast 2-hybrid
RAN	5901	ATP6V1D	51382	pp	--	int.I2D: YeastLow
RPS15A	6210	RPS27A	6233	pp	--	int.I2D: YeastLow
ARCN1	372	COPB2	9276	pp	--	int.I2D: HPRD, BCI; int.HPRD: in vivo
RAN	5901	SKP1	6500	pp	--	int.I2D: BioGrid_Yeast
RPS24	6229	RPS27A	6233	pp	--	int.I2D: YeastMedium

Related GO terms (490)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0022627	cytosolic small ribosomal subunit	2.53e-17	4.13e-13	6.879	9	21	39
GO:0019058	viral life cycle	1.49e-16	2.42e-12	5.608	11	25	115
GO:0005829	cytosol	7.71e-15	1.26e-10	2.315	25	74	2562
GO:0019083	viral transcription	2.96e-14	4.82e-10	5.825	9	22	81
GO:0006413	translational initiation	4.35e-14	7.10e-10	5.283	10	27	131
GO:0006415	translational termination	5.77e-14	9.41e-10	5.721	9	22	87
GO:0006414	translational elongation	1.07e-13	1.75e-09	5.625	9	22	93
GO:0006614	SRP-dependent cotranslational protein targeting to membrane	3.02e-13	4.93e-09	5.464	9	22	104
GO:0016032	viral process	4.35e-13	7.10e-09	3.725	14	37	540
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	7.04e-13	1.15e-08	5.331	9	22	114
GO:0003735	structural constituent of ribosome	4.91e-12	8.01e-08	5.025	9	24	141
GO:0016071	mRNA metabolic process	9.19e-12	1.50e-07	4.515	10	29	223
GO:0006412	translation	1.55e-11	2.52e-07	4.440	10	29	235
GO:0016070	RNA metabolic process	2.53e-11	4.13e-07	4.368	10	29	247
GO:0048205	COPI coating of Golgi vesicle	2.66e-11	4.34e-07	7.616	5	6	13
GO:0030126	COPI vesicle coat	2.66e-11	4.34e-07	7.616	5	6	13
GO:0015935	small ribosomal subunit	1.27e-10	2.07e-06	7.229	5	9	17
GO:0061024	membrane organization	2.97e-10	4.84e-06	4.805	8	11	146
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.08e-09	1.76e-05	6.673	5	6	25
GO:0010467	gene expression	2.17e-09	3.54e-05	3.194	12	36	669
GO:0016020	membrane	3.42e-09	5.59e-05	2.312	17	48	1746
GO:0044822	poly(A) RNA binding	4.24e-09	6.92e-05	2.728	14	42	1078
GO:0044267	cellular protein metabolic process	2.13e-08	3.48e-04	3.365	10	29	495
GO:0075733	intracellular transport of virus	4.57e-06	7.46e-02	6.492	3	3	17
GO:0006891	intra-Golgi vesicle-mediated transport	4.57e-06	7.46e-02	6.492	3	3	17
GO:0005840	ribosome	5.13e-06	8.38e-02	5.112	4	10	59
GO:0034166	toll-like receptor 10 signaling pathway	7.58e-06	1.24e-01	4.972	4	5	65
GO:0034146	toll-like receptor 5 signaling pathway	7.58e-06	1.24e-01	4.972	4	5	65
GO:0036464	cytoplasmic ribonucleoprotein granule	1.03e-05	1.68e-01	6.120	3	5	22
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	1.08e-05	1.76e-01	4.845	4	5	71
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	1.08e-05	1.76e-01	4.845	4	5	71
GO:0034162	toll-like receptor 9 signaling pathway	1.14e-05	1.86e-01	4.825	4	5	72
GO:0034134	toll-like receptor 2 signaling pathway	1.20e-05	1.97e-01	4.805	4	5	73
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	1.41e-05	2.31e-01	4.747	4	5	76
GO:0002756	MyD88-independent toll-like receptor signaling pathway	1.57e-05	2.56e-01	4.709	4	5	78
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	1.73e-05	2.83e-01	4.673	4	5	80
GO:0034138	toll-like receptor 3 signaling pathway	1.73e-05	2.83e-01	4.673	4	5	80
GO:0019843	rRNA binding	1.94e-05	3.17e-01	5.825	3	4	27
GO:0006886	intracellular protein transport	2.02e-05	3.29e-01	3.882	5	6	173
GO:0070062	extracellular vesicular exosome	2.61e-05	4.26e-01	1.604	15	51	2516
GO:0034142	toll-like receptor 4 signaling pathway	3.56e-05	5.81e-01	4.409	4	5	96
GO:0033119	negative regulation of RNA splicing	3.71e-05	6.06e-01	7.673	2	2	5
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway	4.68e-05	7.64e-01	5.409	3	3	36
GO:0002224	toll-like receptor signaling pathway	5.86e-05	9.56e-01	4.226	4	5	109
GO:0007254	JNK cascade	1.34e-04	1.00e+00	4.907	3	3	51
GO:0000086	G2/M transition of mitotic cell cycle	1.42e-04	1.00e+00	3.896	4	6	137
GO:0051403	stress-activated MAPK cascade	1.59e-04	1.00e+00	4.825	3	4	54
GO:0043065	positive regulation of apoptotic process	1.79e-04	1.00e+00	3.218	5	6	274
GO:0000082	G1/S transition of mitotic cell cycle	2.02e-04	1.00e+00	3.766	4	11	150
GO:0032481	positive regulation of type I interferon production	2.28e-04	1.00e+00	4.649	3	3	61
GO:0042274	ribosomal small subunit biogenesis	2.43e-04	1.00e+00	6.409	2	6	12
GO:0019082	viral protein processing	2.43e-04	1.00e+00	6.409	2	2	12
GO:0032479	regulation of type I interferon production	2.87e-04	1.00e+00	6.294	2	2	13
GO:0018105	peptidyl-serine phosphorylation	3.29e-04	1.00e+00	4.471	3	5	69
GO:0005515	protein binding	3.34e-04	1.00e+00	0.873	22	87	6127
GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	3.43e-04	1.00e+00	4.450	3	8	70
GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	4.04e-04	1.00e+00	4.370	3	8	74
GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process	4.89e-04	1.00e+00	4.276	3	8	79
GO:0019068	virion assembly	4.97e-04	1.00e+00	5.907	2	2	17
GO:0007173	epidermal growth factor receptor signaling pathway	5.06e-04	1.00e+00	3.417	4	5	191
GO:0005925	focal adhesion	7.09e-04	1.00e+00	2.785	5	23	370
GO:0007220	Notch receptor processing	8.39e-04	1.00e+00	5.535	2	2	22
GO:0071456	cellular response to hypoxia	9.18e-04	1.00e+00	3.965	3	3	98
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	1.09e-03	1.00e+00	5.351	2	2	25
GO:0005844	polysome	1.09e-03	1.00e+00	5.351	2	2	25
GO:0045087	innate immune response	1.11e-03	1.00e+00	2.313	6	11	616
GO:0003713	transcription coactivator activity	1.17e-03	1.00e+00	3.094	4	6	239
GO:0005978	glycogen biosynthetic process	1.18e-03	1.00e+00	5.294	2	2	26
GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	1.18e-03	1.00e+00	5.294	2	2	26
GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity	1.18e-03	1.00e+00	5.294	2	2	26
GO:0030529	ribonucleoprotein complex	1.42e-03	1.00e+00	3.747	3	8	114
GO:0043066	negative regulation of apoptotic process	1.43e-03	1.00e+00	2.558	5	14	433
GO:0097190	apoptotic signaling pathway	1.49e-03	1.00e+00	3.721	3	3	116
GO:0000209	protein polyubiquitination	1.49e-03	1.00e+00	3.721	3	7	116
GO:0032480	negative regulation of type I interferon production	1.78e-03	1.00e+00	4.994	2	2	32
GO:0051092	positive regulation of NF-kappaB transcription factor activity	1.85e-03	1.00e+00	3.614	3	3	125
GO:0007219	Notch signaling pathway	1.85e-03	1.00e+00	3.614	3	4	125
GO:0048011	neurotrophin TRK receptor signaling pathway	1.90e-03	1.00e+00	2.902	4	5	273
GO:2001286	regulation of caveolin-mediated endocytosis	1.96e-03	1.00e+00	8.994	1	1	1
GO:0022605	oogenesis stage	1.96e-03	1.00e+00	8.994	1	1	1
GO:0071393	cellular response to progesterone stimulus	1.96e-03	1.00e+00	8.994	1	1	1
GO:0033176	proton-transporting V-type ATPase complex	1.96e-03	1.00e+00	8.994	1	1	1
GO:0021691	cerebellar Purkinje cell layer maturation	1.96e-03	1.00e+00	8.994	1	1	1
GO:0007179	transforming growth factor beta receptor signaling pathway	2.07e-03	1.00e+00	3.557	3	4	130
GO:0034332	adherens junction organization	2.25e-03	1.00e+00	4.825	2	4	36
GO:0007249	I-kappaB kinase/NF-kappaB signaling	2.91e-03	1.00e+00	4.637	2	4	41
GO:0035872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	3.20e-03	1.00e+00	4.568	2	2	43
GO:0005198	structural molecule activity	3.66e-03	1.00e+00	3.267	3	5	159
GO:0008543	fibroblast growth factor receptor signaling pathway	3.66e-03	1.00e+00	3.267	3	3	159
GO:0043005	neuron projection	3.79e-03	1.00e+00	3.248	3	6	161
GO:0071338	positive regulation of hair follicle cell proliferation	3.92e-03	1.00e+00	7.994	1	1	2
GO:0071987	WD40-repeat domain binding	3.92e-03	1.00e+00	7.994	1	1	2
GO:0002176	male germ cell proliferation	3.92e-03	1.00e+00	7.994	1	1	2
GO:0060661	submandibular salivary gland formation	3.92e-03	1.00e+00	7.994	1	1	2
GO:0048822	enucleate erythrocyte development	3.92e-03	1.00e+00	7.994	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	3.92e-03	1.00e+00	7.994	1	1	2
GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	3.92e-03	1.00e+00	7.994	1	1	2
GO:0010632	regulation of epithelial cell migration	3.92e-03	1.00e+00	7.994	1	1	2
GO:0001672	regulation of chromatin assembly or disassembly	3.92e-03	1.00e+00	7.994	1	1	2
GO:0090135	actin filament branching	3.92e-03	1.00e+00	7.994	1	1	2
GO:0003682	chromatin binding	3.94e-03	1.00e+00	2.611	4	4	334
GO:0005730	nucleolus	4.03e-03	1.00e+00	1.447	9	36	1684
GO:0007030	Golgi organization	4.30e-03	1.00e+00	4.351	2	3	50
GO:0038095	Fc-epsilon receptor signaling pathway	4.48e-03	1.00e+00	3.162	3	3	171
GO:0005737	cytoplasm	4.56e-03	1.00e+00	0.944	15	65	3976
GO:0007049	cell cycle	4.94e-03	1.00e+00	3.112	3	4	177
GO:0030666	endocytic vesicle membrane	5.00e-03	1.00e+00	4.240	2	2	54
GO:0016197	endosomal transport	5.75e-03	1.00e+00	4.136	2	3	58
GO:0051683	establishment of Golgi localization	5.87e-03	1.00e+00	7.409	1	2	3
GO:0010641	positive regulation of platelet-derived growth factor receptor signaling pathway	5.87e-03	1.00e+00	7.409	1	1	3
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	5.87e-03	1.00e+00	7.409	1	1	3
GO:0003161	cardiac conduction system development	5.87e-03	1.00e+00	7.409	1	1	3
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	5.87e-03	1.00e+00	7.409	1	1	3
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	5.87e-03	1.00e+00	7.409	1	1	3
GO:0005850	eukaryotic translation initiation factor 2 complex	5.87e-03	1.00e+00	7.409	1	1	3
GO:0090045	positive regulation of deacetylase activity	5.87e-03	1.00e+00	7.409	1	1	3
GO:0035033	histone deacetylase regulator activity	5.87e-03	1.00e+00	7.409	1	1	3
GO:2000017	positive regulation of determination of dorsal identity	5.87e-03	1.00e+00	7.409	1	1	3
GO:0000056	ribosomal small subunit export from nucleus	5.87e-03	1.00e+00	7.409	1	2	3
GO:0004705	JUN kinase activity	5.87e-03	1.00e+00	7.409	1	1	3
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	6.96e-03	1.00e+00	3.994	2	2	64
GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	7.17e-03	1.00e+00	3.972	2	6	65
GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	7.17e-03	1.00e+00	3.972	2	6	65
GO:0003924	GTPase activity	7.21e-03	1.00e+00	2.914	3	6	203
GO:0000278	mitotic cell cycle	7.30e-03	1.00e+00	2.358	4	16	398
GO:0031295	T cell costimulation	7.61e-03	1.00e+00	3.928	2	3	67
GO:0007258	JUN phosphorylation	7.82e-03	1.00e+00	6.994	1	1	4
GO:0034191	apolipoprotein A-I receptor binding	7.82e-03	1.00e+00	6.994	1	1	4
GO:0048664	neuron fate determination	7.82e-03	1.00e+00	6.994	1	1	4
GO:0033503	HULC complex	7.82e-03	1.00e+00	6.994	1	1	4
GO:0032463	negative regulation of protein homooligomerization	7.82e-03	1.00e+00	6.994	1	1	4
GO:0051902	negative regulation of mitochondrial depolarization	7.82e-03	1.00e+00	6.994	1	1	4
GO:0031062	positive regulation of histone methylation	7.82e-03	1.00e+00	6.994	1	1	4
GO:0031063	regulation of histone deacetylation	7.82e-03	1.00e+00	6.994	1	1	4
GO:0060684	epithelial-mesenchymal cell signaling	7.82e-03	1.00e+00	6.994	1	1	4
GO:0070851	growth factor receptor binding	7.82e-03	1.00e+00	6.994	1	1	4
GO:0051835	positive regulation of synapse structural plasticity	7.82e-03	1.00e+00	6.994	1	1	4
GO:0031467	Cul7-RING ubiquitin ligase complex	7.82e-03	1.00e+00	6.994	1	1	4
GO:0000055	ribosomal large subunit export from nucleus	7.82e-03	1.00e+00	6.994	1	1	4
GO:0033625	positive regulation of integrin activation	7.82e-03	1.00e+00	6.994	1	1	4
GO:0090231	regulation of spindle checkpoint	7.82e-03	1.00e+00	6.994	1	1	4
GO:0072384	organelle transport along microtubule	7.82e-03	1.00e+00	6.994	1	2	4
GO:0002479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	8.97e-03	1.00e+00	3.805	2	6	73
GO:0003729	mRNA binding	8.97e-03	1.00e+00	3.805	2	3	73
GO:0006184	GTP catabolic process	8.99e-03	1.00e+00	2.798	3	6	220
GO:0031584	activation of phospholipase D activity	9.77e-03	1.00e+00	6.673	1	1	5
GO:2000641	regulation of early endosome to late endosome transport	9.77e-03	1.00e+00	6.673	1	1	5
GO:0036336	dendritic cell migration	9.77e-03	1.00e+00	6.673	1	1	5
GO:0009404	toxin metabolic process	9.77e-03	1.00e+00	6.673	1	1	5
GO:0033033	negative regulation of myeloid cell apoptotic process	9.77e-03	1.00e+00	6.673	1	1	5
GO:0035088	establishment or maintenance of apical/basal cell polarity	9.77e-03	1.00e+00	6.673	1	1	5
GO:0051385	response to mineralocorticoid	9.77e-03	1.00e+00	6.673	1	1	5
GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9.77e-03	1.00e+00	6.673	1	3	5
GO:0005826	actomyosin contractile ring	9.77e-03	1.00e+00	6.673	1	1	5
GO:0097300	programmed necrotic cell death	9.77e-03	1.00e+00	6.673	1	1	5
GO:0031256	leading edge membrane	9.77e-03	1.00e+00	6.673	1	1	5
GO:0071803	positive regulation of podosome assembly	9.77e-03	1.00e+00	6.673	1	1	5
GO:0038096	Fc-gamma receptor signaling pathway involved in phagocytosis	9.94e-03	1.00e+00	3.728	2	4	77
GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I	9.94e-03	1.00e+00	3.728	2	6	77
GO:0007067	mitotic nuclear division	1.03e-02	1.00e+00	2.728	3	7	231
GO:0071222	cellular response to lipopolysaccharide	1.10e-02	1.00e+00	3.655	2	4	81
GO:0050847	progesterone receptor signaling pathway	1.17e-02	1.00e+00	6.409	1	1	6
GO:0007143	female meiotic division	1.17e-02	1.00e+00	6.409	1	1	6
GO:0002309	T cell proliferation involved in immune response	1.17e-02	1.00e+00	6.409	1	1	6
GO:0045182	translation regulator activity	1.17e-02	1.00e+00	6.409	1	2	6
GO:0045056	transcytosis	1.17e-02	1.00e+00	6.409	1	1	6
GO:0000974	Prp19 complex	1.17e-02	1.00e+00	6.409	1	1	6
GO:0060789	hair follicle placode formation	1.17e-02	1.00e+00	6.409	1	1	6
GO:0048554	positive regulation of metalloenzyme activity	1.17e-02	1.00e+00	6.409	1	1	6
GO:0006924	activation-induced cell death of T cells	1.17e-02	1.00e+00	6.409	1	2	6
GO:0050852	T cell receptor signaling pathway	1.28e-02	1.00e+00	3.535	2	2	88
GO:0000187	activation of MAPK activity	1.34e-02	1.00e+00	3.503	2	3	90
GO:0050658	RNA transport	1.36e-02	1.00e+00	6.187	1	1	7
GO:0007097	nuclear migration	1.36e-02	1.00e+00	6.187	1	2	7
GO:0061512	protein localization to cilium	1.36e-02	1.00e+00	6.187	1	1	7
GO:0003334	keratinocyte development	1.36e-02	1.00e+00	6.187	1	1	7
GO:0051988	regulation of attachment of spindle microtubules to kinetochore	1.36e-02	1.00e+00	6.187	1	1	7
GO:0000028	ribosomal small subunit assembly	1.36e-02	1.00e+00	6.187	1	3	7
GO:0010447	response to acidic pH	1.36e-02	1.00e+00	6.187	1	1	7
GO:0034101	erythrocyte homeostasis	1.36e-02	1.00e+00	6.187	1	1	7
GO:0010907	positive regulation of glucose metabolic process	1.36e-02	1.00e+00	6.187	1	1	7
GO:0048193	Golgi vesicle transport	1.36e-02	1.00e+00	6.187	1	1	7
GO:0030157	pancreatic juice secretion	1.36e-02	1.00e+00	6.187	1	1	7
GO:0060136	embryonic process involved in female pregnancy	1.36e-02	1.00e+00	6.187	1	1	7
GO:0000930	gamma-tubulin complex	1.36e-02	1.00e+00	6.187	1	1	7
GO:0043497	regulation of protein heterodimerization activity	1.36e-02	1.00e+00	6.187	1	1	7
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	1.46e-02	1.00e+00	3.440	2	7	94
GO:0001649	osteoblast differentiation	1.48e-02	1.00e+00	3.425	2	3	95
GO:0006364	rRNA processing	1.51e-02	1.00e+00	3.409	2	8	96
GO:0043114	regulation of vascular permeability	1.56e-02	1.00e+00	5.994	1	1	8
GO:0045124	regulation of bone resorption	1.56e-02	1.00e+00	5.994	1	1	8
GO:0051489	regulation of filopodium assembly	1.56e-02	1.00e+00	5.994	1	1	8
GO:0033523	histone H2B ubiquitination	1.56e-02	1.00e+00	5.994	1	1	8
GO:0007172	signal complex assembly	1.56e-02	1.00e+00	5.994	1	1	8
GO:0034067	protein localization to Golgi apparatus	1.75e-02	1.00e+00	5.825	1	1	9
GO:0090136	epithelial cell-cell adhesion	1.75e-02	1.00e+00	5.825	1	2	9
GO:0047497	mitochondrion transport along microtubule	1.75e-02	1.00e+00	5.825	1	1	9
GO:0071732	cellular response to nitric oxide	1.75e-02	1.00e+00	5.825	1	1	9
GO:0046628	positive regulation of insulin receptor signaling pathway	1.75e-02	1.00e+00	5.825	1	1	9
GO:0007264	small GTPase mediated signal transduction	1.88e-02	1.00e+00	2.399	3	7	290
GO:0031274	positive regulation of pseudopodium assembly	1.94e-02	1.00e+00	5.673	1	2	10
GO:0022407	regulation of cell-cell adhesion	1.94e-02	1.00e+00	5.673	1	1	10
GO:0005798	Golgi-associated vesicle	1.94e-02	1.00e+00	5.673	1	1	10
GO:0060047	heart contraction	1.94e-02	1.00e+00	5.673	1	1	10
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	2.14e-02	1.00e+00	5.535	1	1	11
GO:0060065	uterus development	2.14e-02	1.00e+00	5.535	1	1	11
GO:0051895	negative regulation of focal adhesion assembly	2.14e-02	1.00e+00	5.535	1	1	11
GO:0045120	pronucleus	2.14e-02	1.00e+00	5.535	1	1	11
GO:0010390	histone monoubiquitination	2.14e-02	1.00e+00	5.535	1	1	11
GO:0035518	histone H2A monoubiquitination	2.14e-02	1.00e+00	5.535	1	2	11
GO:2000573	positive regulation of DNA biosynthetic process	2.14e-02	1.00e+00	5.535	1	2	11
GO:0006006	glucose metabolic process	2.27e-02	1.00e+00	3.100	2	4	119
GO:0061136	regulation of proteasomal protein catabolic process	2.33e-02	1.00e+00	5.409	1	1	12
GO:0007051	spindle organization	2.33e-02	1.00e+00	5.409	1	1	12
GO:0043249	erythrocyte maturation	2.33e-02	1.00e+00	5.409	1	1	12
GO:0043149	stress fiber assembly	2.33e-02	1.00e+00	5.409	1	2	12
GO:1901214	regulation of neuron death	2.33e-02	1.00e+00	5.409	1	1	12
GO:0031929	TOR signaling	2.52e-02	1.00e+00	5.294	1	1	13
GO:0005662	DNA replication factor A complex	2.52e-02	1.00e+00	5.294	1	1	13
GO:0071398	cellular response to fatty acid	2.52e-02	1.00e+00	5.294	1	2	13
GO:0060444	branching involved in mammary gland duct morphogenesis	2.52e-02	1.00e+00	5.294	1	1	13
GO:0005525	GTP binding	2.59e-02	1.00e+00	2.222	3	6	328
GO:0035371	microtubule plus-end	2.71e-02	1.00e+00	5.187	1	1	14
GO:0031333	negative regulation of protein complex assembly	2.71e-02	1.00e+00	5.187	1	1	14
GO:0071480	cellular response to gamma radiation	2.71e-02	1.00e+00	5.187	1	1	14
GO:0031996	thioesterase binding	2.71e-02	1.00e+00	5.187	1	1	14
GO:0050662	coenzyme binding	2.71e-02	1.00e+00	5.187	1	1	14
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.71e-02	1.00e+00	1.792	4	9	589
GO:0009615	response to virus	2.75e-02	1.00e+00	2.950	2	4	132
GO:0005634	nucleus	2.88e-02	1.00e+00	0.664	15	66	4828
GO:0048821	erythrocyte development	2.90e-02	1.00e+00	5.088	1	2	15
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	2.90e-02	1.00e+00	5.088	1	1	15
GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	2.90e-02	1.00e+00	5.088	1	1	15
GO:0048477	oogenesis	2.90e-02	1.00e+00	5.088	1	1	15
GO:0030131	clathrin adaptor complex	2.90e-02	1.00e+00	5.088	1	1	15
GO:0030225	macrophage differentiation	2.90e-02	1.00e+00	5.088	1	1	15
GO:0031369	translation initiation factor binding	2.90e-02	1.00e+00	5.088	1	2	15
GO:0051233	spindle midzone	2.90e-02	1.00e+00	5.088	1	2	15
GO:0042176	regulation of protein catabolic process	3.09e-02	1.00e+00	4.994	1	4	16
GO:0014911	positive regulation of smooth muscle cell migration	3.09e-02	1.00e+00	4.994	1	1	16
GO:2000811	negative regulation of anoikis	3.09e-02	1.00e+00	4.994	1	1	16
GO:0048037	cofactor binding	3.09e-02	1.00e+00	4.994	1	1	16
GO:0008286	insulin receptor signaling pathway	3.23e-02	1.00e+00	2.825	2	4	144
GO:0030742	GTP-dependent protein binding	3.28e-02	1.00e+00	4.907	1	1	17
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	3.39e-02	1.00e+00	2.785	2	3	148
GO:0010628	positive regulation of gene expression	3.43e-02	1.00e+00	2.775	2	4	149
GO:0070064	proline-rich region binding	3.47e-02	1.00e+00	4.825	1	1	18
GO:0010507	negative regulation of autophagy	3.47e-02	1.00e+00	4.825	1	1	18
GO:0031954	positive regulation of protein autophosphorylation	3.47e-02	1.00e+00	4.825	1	1	18
GO:0090316	positive regulation of intracellular protein transport	3.47e-02	1.00e+00	4.825	1	1	18
GO:0042981	regulation of apoptotic process	3.52e-02	1.00e+00	2.756	2	7	151
GO:0006259	DNA metabolic process	3.66e-02	1.00e+00	4.747	1	1	19
GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	3.66e-02	1.00e+00	4.747	1	1	19
GO:0007088	regulation of mitosis	3.66e-02	1.00e+00	4.747	1	1	19
GO:0045453	bone resorption	3.66e-02	1.00e+00	4.747	1	1	19
GO:0031667	response to nutrient levels	3.66e-02	1.00e+00	4.747	1	1	19
GO:0005794	Golgi apparatus	3.70e-02	1.00e+00	1.650	4	8	650
GO:0010008	endosome membrane	3.78e-02	1.00e+00	2.700	2	2	157
GO:0032148	activation of protein kinase B activity	3.85e-02	1.00e+00	4.673	1	1	20
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	3.85e-02	1.00e+00	4.673	1	2	20
GO:0043473	pigmentation	3.85e-02	1.00e+00	4.673	1	2	20
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator	3.85e-02	1.00e+00	4.673	1	1	20
GO:0043393	regulation of protein binding	3.85e-02	1.00e+00	4.673	1	2	20
GO:0046847	filopodium assembly	4.04e-02	1.00e+00	4.602	1	1	21
GO:0007369	gastrulation	4.04e-02	1.00e+00	4.602	1	1	21
GO:0051881	regulation of mitochondrial membrane potential	4.04e-02	1.00e+00	4.602	1	1	21
GO:0008284	positive regulation of cell proliferation	4.08e-02	1.00e+00	1.965	3	7	392
GO:0034220	ion transmembrane transport	4.22e-02	1.00e+00	2.611	2	2	167
GO:0001106	RNA polymerase II transcription corepressor activity	4.23e-02	1.00e+00	4.535	1	1	22
GO:0031435	mitogen-activated protein kinase kinase kinase binding	4.23e-02	1.00e+00	4.535	1	1	22
GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	4.23e-02	1.00e+00	4.535	1	1	22
GO:0046686	response to cadmium ion	4.23e-02	1.00e+00	4.535	1	1	22
GO:0007052	mitotic spindle organization	4.23e-02	1.00e+00	4.535	1	1	22
GO:0001892	embryonic placenta development	4.42e-02	1.00e+00	4.471	1	1	23
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	4.42e-02	1.00e+00	4.471	1	1	23
GO:0051297	centrosome organization	4.42e-02	1.00e+00	4.471	1	2	23
GO:0045787	positive regulation of cell cycle	4.42e-02	1.00e+00	4.471	1	2	23
GO:0002040	sprouting angiogenesis	4.42e-02	1.00e+00	4.471	1	1	23
GO:0051017	actin filament bundle assembly	4.42e-02	1.00e+00	4.471	1	1	23
GO:0000139	Golgi membrane	4.50e-02	1.00e+00	1.907	3	7	408
GO:0008135	translation factor activity, nucleic acid binding	4.60e-02	1.00e+00	4.409	1	4	24
GO:0007163	establishment or maintenance of cell polarity	4.60e-02	1.00e+00	4.409	1	2	24
GO:0051602	response to electrical stimulus	4.60e-02	1.00e+00	4.409	1	1	24
GO:0006611	protein export from nucleus	4.79e-02	1.00e+00	4.351	1	1	25
GO:0050715	positive regulation of cytokine secretion	4.79e-02	1.00e+00	4.351	1	1	25
GO:0031519	PcG protein complex	4.79e-02	1.00e+00	4.351	1	1	25
GO:0048705	skeletal system morphogenesis	4.79e-02	1.00e+00	4.351	1	1	25
GO:0019904	protein domain specific binding	4.88e-02	1.00e+00	2.495	2	3	181
GO:1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	4.98e-02	1.00e+00	4.294	1	1	26
GO:0045859	regulation of protein kinase activity	4.98e-02	1.00e+00	4.294	1	1	26
GO:0006367	transcription initiation from RNA polymerase II promoter	5.03e-02	1.00e+00	2.471	2	5	184
GO:0031424	keratinization	5.17e-02	1.00e+00	4.240	1	1	27
GO:0051149	positive regulation of muscle cell differentiation	5.17e-02	1.00e+00	4.240	1	2	27
GO:0032720	negative regulation of tumor necrosis factor production	5.17e-02	1.00e+00	4.240	1	1	27
GO:0001103	RNA polymerase II repressing transcription factor binding	5.17e-02	1.00e+00	4.240	1	1	27
GO:0030331	estrogen receptor binding	5.17e-02	1.00e+00	4.240	1	1	27
GO:2001238	positive regulation of extrinsic apoptotic signaling pathway	5.17e-02	1.00e+00	4.240	1	1	27
GO:0031069	hair follicle morphogenesis	5.17e-02	1.00e+00	4.240	1	1	27
GO:0032467	positive regulation of cytokinesis	5.35e-02	1.00e+00	4.187	1	1	28
GO:0042626	ATPase activity, coupled to transmembrane movement of substances	5.35e-02	1.00e+00	4.187	1	1	28
GO:0019005	SCF ubiquitin ligase complex	5.54e-02	1.00e+00	4.136	1	1	29
GO:0034605	cellular response to heat	5.54e-02	1.00e+00	4.136	1	1	29
GO:0072686	mitotic spindle	5.54e-02	1.00e+00	4.136	1	1	29
GO:0042169	SH2 domain binding	5.72e-02	1.00e+00	4.088	1	1	30
GO:0031647	regulation of protein stability	5.72e-02	1.00e+00	4.088	1	1	30
GO:0007346	regulation of mitotic cell cycle	5.72e-02	1.00e+00	4.088	1	3	30
GO:0040018	positive regulation of multicellular organism growth	5.72e-02	1.00e+00	4.088	1	1	30
GO:0046875	ephrin receptor binding	5.72e-02	1.00e+00	4.088	1	2	30
GO:0070555	response to interleukin-1	5.91e-02	1.00e+00	4.040	1	1	31
GO:0007093	mitotic cell cycle checkpoint	5.91e-02	1.00e+00	4.040	1	2	31
GO:0005654	nucleoplasm	6.00e-02	1.00e+00	1.220	5	26	1095
GO:0015992	proton transport	6.09e-02	1.00e+00	3.994	1	1	32
GO:0051219	phosphoprotein binding	6.09e-02	1.00e+00	3.994	1	4	32
GO:0033572	transferrin transport	6.09e-02	1.00e+00	3.994	1	1	32
GO:0032091	negative regulation of protein binding	6.28e-02	1.00e+00	3.950	1	1	33
GO:0033077	T cell differentiation in thymus	6.28e-02	1.00e+00	3.950	1	1	33
GO:0005158	insulin receptor binding	6.28e-02	1.00e+00	3.950	1	2	33
GO:0048812	neuron projection morphogenesis	6.28e-02	1.00e+00	3.950	1	1	33
GO:0042692	muscle cell differentiation	6.46e-02	1.00e+00	3.907	1	2	34
GO:0001890	placenta development	6.46e-02	1.00e+00	3.907	1	1	34
GO:0051701	interaction with host	6.46e-02	1.00e+00	3.907	1	1	34
GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	6.65e-02	1.00e+00	3.865	1	1	35
GO:0071560	cellular response to transforming growth factor beta stimulus	6.83e-02	1.00e+00	3.825	1	1	36
GO:0030178	negative regulation of Wnt signaling pathway	6.83e-02	1.00e+00	3.825	1	1	36
GO:0045893	positive regulation of transcription, DNA-templated	6.92e-02	1.00e+00	1.652	3	8	487
GO:0016301	kinase activity	7.01e-02	1.00e+00	3.785	1	2	37
GO:0018107	peptidyl-threonine phosphorylation	7.01e-02	1.00e+00	3.785	1	1	37
GO:0032880	regulation of protein localization	7.01e-02	1.00e+00	3.785	1	1	37
GO:0097191	extrinsic apoptotic signaling pathway	7.19e-02	1.00e+00	3.747	1	3	38
GO:0045740	positive regulation of DNA replication	7.19e-02	1.00e+00	3.747	1	1	38
GO:0050681	androgen receptor binding	7.19e-02	1.00e+00	3.747	1	2	38
GO:0090382	phagosome maturation	7.19e-02	1.00e+00	3.747	1	1	38
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	7.23e-02	1.00e+00	1.331	4	11	811
GO:0008047	enzyme activator activity	7.38e-02	1.00e+00	3.709	1	1	39
GO:0032092	positive regulation of protein binding	7.38e-02	1.00e+00	3.709	1	1	39
GO:0019221	cytokine-mediated signaling pathway	7.44e-02	1.00e+00	2.149	2	5	230
GO:0042542	response to hydrogen peroxide	7.56e-02	1.00e+00	3.673	1	1	40
GO:0045785	positive regulation of cell adhesion	7.74e-02	1.00e+00	3.637	1	1	41
GO:0070301	cellular response to hydrogen peroxide	7.74e-02	1.00e+00	3.637	1	1	41
GO:0030521	androgen receptor signaling pathway	7.74e-02	1.00e+00	3.637	1	3	41
GO:0055085	transmembrane transport	7.86e-02	1.00e+00	1.574	3	3	514
GO:0042147	retrograde transport, endosome to Golgi	7.92e-02	1.00e+00	3.602	1	1	42
GO:0005902	microvillus	7.92e-02	1.00e+00	3.602	1	1	42
GO:0004715	non-membrane spanning protein tyrosine kinase activity	7.92e-02	1.00e+00	3.602	1	1	42
GO:0007286	spermatid development	8.28e-02	1.00e+00	3.535	1	1	44
GO:0034613	cellular protein localization	8.28e-02	1.00e+00	3.535	1	2	44
GO:0005080	protein kinase C binding	8.28e-02	1.00e+00	3.535	1	1	44
GO:0009411	response to UV	8.46e-02	1.00e+00	3.503	1	2	45
GO:0021762	substantia nigra development	8.64e-02	1.00e+00	3.471	1	2	46
GO:0044297	cell body	8.64e-02	1.00e+00	3.471	1	1	46
GO:0043525	positive regulation of neuron apoptotic process	8.64e-02	1.00e+00	3.471	1	2	46
GO:0045727	positive regulation of translation	8.64e-02	1.00e+00	3.471	1	1	46
GO:0043406	positive regulation of MAP kinase activity	8.82e-02	1.00e+00	3.440	1	1	47
GO:0043025	neuronal cell body	8.82e-02	1.00e+00	2.006	2	5	254
GO:0008344	adult locomotory behavior	8.82e-02	1.00e+00	3.440	1	2	47
GO:0004842	ubiquitin-protein transferase activity	8.94e-02	1.00e+00	1.994	2	3	256
GO:0006950	response to stress	9.00e-02	1.00e+00	3.409	1	1	48
GO:0019003	GDP binding	9.00e-02	1.00e+00	3.409	1	1	48
GO:0005070	SH3/SH2 adaptor activity	9.18e-02	1.00e+00	3.380	1	1	49
GO:0003743	translation initiation factor activity	9.18e-02	1.00e+00	3.380	1	5	49
GO:0006281	DNA repair	9.42e-02	1.00e+00	1.950	2	5	264
GO:0090263	positive regulation of canonical Wnt signaling pathway	9.54e-02	1.00e+00	3.322	1	1	51
GO:0030900	forebrain development	9.54e-02	1.00e+00	3.322	1	1	51
GO:0008202	steroid metabolic process	9.72e-02	1.00e+00	3.294	1	1	52
GO:0006952	defense response	9.89e-02	1.00e+00	3.267	1	1	53
GO:0030175	filopodium	9.89e-02	1.00e+00	3.267	1	2	53
GO:0005975	carbohydrate metabolic process	1.00e-01	1.00e+00	1.896	2	3	274
GO:0006915	apoptotic process	1.00e-01	1.00e+00	1.422	3	9	571
GO:0009612	response to mechanical stimulus	1.01e-01	1.00e+00	3.240	1	1	54
GO:0097193	intrinsic apoptotic signaling pathway	1.02e-01	1.00e+00	3.213	1	2	55
GO:0002039	p53 binding	1.02e-01	1.00e+00	3.213	1	1	55
GO:0046330	positive regulation of JNK cascade	1.02e-01	1.00e+00	3.213	1	1	55
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	1.06e-01	1.00e+00	3.162	1	1	57
GO:0006879	cellular iron ion homeostasis	1.06e-01	1.00e+00	3.162	1	2	57
GO:0019899	enzyme binding	1.09e-01	1.00e+00	1.825	2	5	288
GO:0005643	nuclear pore	1.10e-01	1.00e+00	3.112	1	1	59
GO:0033138	positive regulation of peptidyl-serine phosphorylation	1.13e-01	1.00e+00	3.064	1	1	61
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	1.15e-01	1.00e+00	3.040	1	1	62
GO:0000151	ubiquitin ligase complex	1.17e-01	1.00e+00	3.017	1	1	63
GO:0005901	caveola	1.17e-01	1.00e+00	3.017	1	1	63
GO:0043234	protein complex	1.17e-01	1.00e+00	1.766	2	9	300
GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	1.17e-01	1.00e+00	3.017	1	2	63
GO:0006417	regulation of translation	1.17e-01	1.00e+00	3.017	1	4	63
GO:0007059	chromosome segregation	1.18e-01	1.00e+00	2.994	1	3	64
GO:0032869	cellular response to insulin stimulus	1.18e-01	1.00e+00	2.994	1	2	64
GO:0016491	oxidoreductase activity	1.20e-01	1.00e+00	2.972	1	1	65
GO:0005882	intermediate filament	1.22e-01	1.00e+00	2.950	1	3	66
GO:0071260	cellular response to mechanical stimulus	1.22e-01	1.00e+00	2.950	1	3	66
GO:0030141	secretory granule	1.23e-01	1.00e+00	2.928	1	2	67
GO:0004674	protein serine/threonine kinase activity	1.24e-01	1.00e+00	1.709	2	6	312
GO:0035556	intracellular signal transduction	1.28e-01	1.00e+00	1.686	2	5	317
GO:0035264	multicellular organism growth	1.29e-01	1.00e+00	2.865	1	1	70
GO:0019901	protein kinase binding	1.30e-01	1.00e+00	1.673	2	9	320
GO:0042393	histone binding	1.30e-01	1.00e+00	2.845	1	1	71
GO:0001503	ossification	1.30e-01	1.00e+00	2.845	1	2	71
GO:0000785	chromatin	1.34e-01	1.00e+00	2.805	1	2	73
GO:0007411	axon guidance	1.34e-01	1.00e+00	1.641	2	3	327
GO:0042826	histone deacetylase binding	1.35e-01	1.00e+00	2.785	1	1	74
GO:0060070	canonical Wnt signaling pathway	1.37e-01	1.00e+00	2.766	1	2	75
GO:0007265	Ras protein signal transduction	1.37e-01	1.00e+00	2.766	1	3	75
GO:0051897	positive regulation of protein kinase B signaling	1.37e-01	1.00e+00	2.766	1	1	75
GO:0043231	intracellular membrane-bounded organelle	1.38e-01	1.00e+00	1.619	2	3	332
GO:0044325	ion channel binding	1.41e-01	1.00e+00	2.728	1	3	77
GO:0008584	male gonad development	1.41e-01	1.00e+00	2.728	1	1	77
GO:0007229	integrin-mediated signaling pathway	1.42e-01	1.00e+00	2.709	1	2	78
GO:0005813	centrosome	1.42e-01	1.00e+00	1.589	2	9	339
GO:0071013	catalytic step 2 spliceosome	1.44e-01	1.00e+00	2.691	1	1	79
GO:0010629	negative regulation of gene expression	1.46e-01	1.00e+00	2.673	1	2	80
GO:0005739	mitochondrion	1.46e-01	1.00e+00	0.964	4	10	1046
GO:0051301	cell division	1.47e-01	1.00e+00	2.655	1	2	81
GO:0045177	apical part of cell	1.49e-01	1.00e+00	2.637	1	1	82
GO:0004713	protein tyrosine kinase activity	1.49e-01	1.00e+00	2.637	1	1	82
GO:0030336	negative regulation of cell migration	1.51e-01	1.00e+00	2.619	1	2	83
GO:0005179	hormone activity	1.52e-01	1.00e+00	2.602	1	1	84
GO:0005929	cilium	1.52e-01	1.00e+00	2.602	1	2	84
GO:0003723	RNA binding	1.53e-01	1.00e+00	1.523	2	10	355
GO:0042593	glucose homeostasis	1.61e-01	1.00e+00	2.519	1	1	89
GO:0042384	cilium assembly	1.62e-01	1.00e+00	2.503	1	2	90
GO:0000922	spindle pole	1.64e-01	1.00e+00	2.487	1	5	91
GO:0016363	nuclear matrix	1.66e-01	1.00e+00	2.471	1	4	92
GO:0016337	single organismal cell-cell adhesion	1.66e-01	1.00e+00	2.471	1	2	92
GO:0042470	melanosome	1.66e-01	1.00e+00	2.471	1	2	92
GO:0005770	late endosome	1.69e-01	1.00e+00	2.440	1	1	94
GO:0007010	cytoskeleton organization	1.72e-01	1.00e+00	2.409	1	1	96
GO:0005178	integrin binding	1.74e-01	1.00e+00	2.395	1	1	97
GO:0016568	chromatin modification	1.77e-01	1.00e+00	2.365	1	2	99
GO:0014069	postsynaptic density	1.88e-01	1.00e+00	2.267	1	3	106
GO:0030496	midbody	1.93e-01	1.00e+00	2.226	1	4	109
GO:0006351	transcription, DNA-templated	1.95e-01	1.00e+00	0.686	5	17	1585
GO:0005815	microtubule organizing center	1.95e-01	1.00e+00	2.213	1	4	110
GO:0070374	positive regulation of ERK1 and ERK2 cascade	1.95e-01	1.00e+00	2.213	1	1	110
GO:0020037	heme binding	1.96e-01	1.00e+00	2.200	1	1	111
GO:0050900	leukocyte migration	1.96e-01	1.00e+00	2.200	1	1	111
GO:0015630	microtubule cytoskeleton	1.98e-01	1.00e+00	2.187	1	4	112
GO:0005819	spindle	2.01e-01	1.00e+00	2.162	1	4	114
GO:0005802	trans-Golgi network	2.04e-01	1.00e+00	2.136	1	2	116
GO:0032496	response to lipopolysaccharide	2.14e-01	1.00e+00	2.064	1	1	122
GO:0051056	regulation of small GTPase mediated signal transduction	2.15e-01	1.00e+00	2.052	1	3	123
GO:0006511	ubiquitin-dependent protein catabolic process	2.21e-01	1.00e+00	2.006	1	3	127
GO:0030036	actin cytoskeleton organization	2.24e-01	1.00e+00	1.983	1	3	129
GO:0046983	protein dimerization activity	2.28e-01	1.00e+00	1.961	1	3	131
GO:0007596	blood coagulation	2.31e-01	1.00e+00	1.136	2	5	464
GO:0018108	peptidyl-tyrosine phosphorylation	2.31e-01	1.00e+00	1.939	1	1	133
GO:0006468	protein phosphorylation	2.33e-01	1.00e+00	1.127	2	6	467
GO:0016055	Wnt signaling pathway	2.43e-01	1.00e+00	1.855	1	3	141
GO:0005911	cell-cell junction	2.44e-01	1.00e+00	1.845	1	2	142
GO:0006974	cellular response to DNA damage stimulus	2.68e-01	1.00e+00	1.691	1	3	158
GO:0046777	protein autophosphorylation	2.68e-01	1.00e+00	1.691	1	1	158
GO:0008022	protein C-terminus binding	2.72e-01	1.00e+00	1.664	1	4	161
GO:0048471	perinuclear region of cytoplasm	2.74e-01	1.00e+00	0.964	2	9	523
GO:0000398	mRNA splicing, via spliceosome	2.78e-01	1.00e+00	1.628	1	2	165
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	2.82e-01	1.00e+00	1.602	1	4	168
GO:0007165	signal transduction	2.85e-01	1.00e+00	0.688	3	7	950
GO:0016607	nuclear speck	2.92e-01	1.00e+00	1.543	1	2	175
GO:0004672	protein kinase activity	2.96e-01	1.00e+00	1.519	1	4	178
GO:0031625	ubiquitin protein ligase binding	2.99e-01	1.00e+00	1.503	1	4	180
GO:0005764	lysosome	3.02e-01	1.00e+00	1.487	1	2	182
GO:0030168	platelet activation	3.33e-01	1.00e+00	1.315	1	4	205
GO:0001701	in utero embryonic development	3.40e-01	1.00e+00	1.280	1	2	210
GO:0004871	signal transducer activity	3.47e-01	1.00e+00	1.240	1	1	216
GO:0005765	lysosomal membrane	3.50e-01	1.00e+00	1.226	1	2	218
GO:0016874	ligase activity	3.58e-01	1.00e+00	1.187	1	2	224
GO:0030425	dendrite	3.78e-01	1.00e+00	1.088	1	3	240
GO:0005102	receptor binding	4.12e-01	1.00e+00	0.928	1	2	268
GO:0000166	nucleotide binding	4.16e-01	1.00e+00	0.907	1	2	272
GO:0003779	actin binding	4.20e-01	1.00e+00	0.891	1	3	275
GO:0007283	spermatogenesis	4.21e-01	1.00e+00	0.886	1	2	276
GO:0042493	response to drug	4.35e-01	1.00e+00	0.825	1	2	288
GO:0016567	protein ubiquitination	4.47e-01	1.00e+00	0.770	1	3	299
GO:0005743	mitochondrial inner membrane	4.48e-01	1.00e+00	0.766	1	1	300
GO:0005856	cytoskeleton	4.60e-01	1.00e+00	0.714	1	6	311
GO:0044281	small molecule metabolic process	4.72e-01	1.00e+00	0.241	3	16	1295
GO:0008283	cell proliferation	4.81e-01	1.00e+00	0.624	1	4	331
GO:0005886	plasma membrane	4.90e-01	1.00e+00	0.111	6	24	2834
GO:0007275	multicellular organismal development	4.95e-01	1.00e+00	0.568	1	2	344
GO:0005524	ATP binding	5.02e-01	1.00e+00	0.176	3	19	1354
GO:0008285	negative regulation of cell proliferation	5.17e-01	1.00e+00	0.475	1	3	367
GO:0007155	cell adhesion	5.34e-01	1.00e+00	0.409	1	3	384
GO:0046872	metal ion binding	5.57e-01	1.00e+00	0.063	3	14	1465
GO:0045892	negative regulation of transcription, DNA-templated	5.70e-01	1.00e+00	0.267	1	2	424
GO:0006366	transcription from RNA polymerase II promoter	5.71e-01	1.00e+00	0.263	1	3	425
GO:0055114	oxidation-reduction process	6.16e-01	1.00e+00	0.085	1	2	481
GO:0042802	identical protein binding	6.24e-01	1.00e+00	0.055	1	4	491
GO:0006355	regulation of transcription, DNA-templated	6.47e-01	1.00e+00	-0.114	2	10	1104
GO:0005783	endoplasmic reticulum	7.05e-01	1.00e+00	-0.258	1	6	610
GO:0003700	sequence-specific DNA binding transcription factor activity	7.77e-01	1.00e+00	-0.552	1	9	748
GO:0005887	integral component of plasma membrane	8.57e-01	1.00e+00	-0.914	1	2	961
GO:0005615	extracellular space	8.71e-01	1.00e+00	-0.986	1	3	1010
GO:0008270	zinc ion binding	8.85e-01	1.00e+00	-1.065	1	7	1067
GO:0003677	DNA binding	9.37e-01	1.00e+00	-1.405	1	14	1351

Tai-Luciferase

meta-reg-snw-988

Interacting subnets

Genes (32)

Interactions (65)

Related GO terms (490)