meta-reg-snw-4904

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-56848 tai-screen-luciferase 6.375 2.94e-136 3.59e-07 2.58e-03 24 19
reg-snw-4904 tai-screen-luciferase 5.516 1.01e-34 8.14e-06 1.73e-05 6 4
int-snw-6150 tai-screen-luciferase 6.375 3.15e-136 3.60e-07 2.59e-03 23 17
int-snw-4831 tai-screen-luciferase 6.314 3.38e-133 5.36e-07 3.08e-03 24 20
int-snw-51741 tai-screen-luciferase 6.174 2.67e-126 1.32e-06 4.54e-03 24 19
tai-screen-luciferase-meta-reg-snw-4904 subnetwork

Genes (49)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS20 6224 22-4.7576.314153Yes-
RPS8 6202 33-5.5457.555234--
MAPK8 5599 28-4.4036.468153--
CHMP2A 27243 33-9.0377.55541YesYes
RPS15 6209 30-5.0407.011116Yes-
COPA 1314 48-9.3955.672340YesYes
RNF20 56254 28-4.5646.17418--
RPS29 6235 17-8.3866.59729--
HSF1 3297 46-4.1795.027209-Yes
SRC 6714 28-2.8066.174419Yes-
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
RPS16 6217 38-5.4444.880205--
CDC42 998 44-6.9604.707276YesYes
RPS11 6205 44-6.5887.555175Yes-
NME2 4831 24-3.0344.32553--
RPS6 6194 44-5.6038.046217Yes-
MRPS12 6183 35-5.4215.516341Yes-
YBX1 4904 24-3.0335.516296--
RAN 5901 38-3.8094.325258YesYes
UBB 7314 30-4.2896.428147--
MAP3K14 9020 15-3.4626.375138-Yes
COPB1 1315 39-6.2219.063118YesYes
SERBP1 26135 35-4.6125.516106-Yes
RPS23 6228 21-4.4856.375118Yes-
RPS13 6207 43-6.5897.555174Yes-
CDC5L 988 34-3.4195.672155--
RPS24 6229 46-7.0348.389217Yes-
VIM 7431 18-3.7606.428246--
RPAP2 79871 153.1116.37549--
TCERG1 10915 28-3.8086.17458Yes-
RPS9 6203 45-7.1277.555140Yes-
RPS3A 6189 19-4.6477.189166Yes-
RPS4X 6191 44-6.7477.555263Yes-
COPZ1 22818 48-8.3019.06313YesYes
ATP6V1D 51382 30-4.1317.286149--
RPS15A 6210 36-5.4137.555177Yes-
WDR46 9277 31-4.2904.226101YesYes
WWOX 51741 28-2.4486.17438--
RPS27A 6233 45-5.6318.389344Yes-
RPS7 6201 15-4.3826.375165Yes-
RPS14 6208 23-4.8037.011204Yes-
RPS19 6223 21-4.7014.752102Yes-
SKP1 6500 26-3.7506.413203--
NFKBIB 4793 28-3.9786.17478--
SPHK2 56848 17-3.0106.37537--
RPS26 6231 43-7.4788.04660Yes-
ARCN1 372 48-8.2329.063118YesYes
MRPL23 6150 15-2.5716.3759--

Interactions (175)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS20 6224 RPS26 6231 pp -- int.I2D: YeastLow
RPS4X 6191 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS27A 6233 SKP1 6500 pp -- int.I2D: BioGrid_Yeast, YeastLow
YBX1 4904 RPS23 6228 pp -- int.Intact: MI:0914(association)
NME2 4831 RPS19 6223 pp -- int.Proteinpedia: Mass spectrometry
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
RPS20 6224 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS13 6207 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, HPRD, IntAct, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro
VIM 7431 SERBP1 26135 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, HPRD, BioGrid, MINT, StelzlHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
RPS11 6205 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS11 6205 RPS19 6223 pp -- int.I2D: IntAct_Yeast
RPS7 6201 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
TCERG1 10915 WWOX 51741 pp -- int.I2D: BioGrid, MINT, Pawson1;
int.Mint: MI:0915(physical association)
RPS3A 6189 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
SRC 6714 CKAP5 9793 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
YBX1 4904 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
YBX1 4904 RPS7 6201 pp -- int.Intact: MI:0914(association)
ARCN1 372 RAN 5901 pp -- int.I2D: YeastLow
RPS15 6209 RPS23 6228 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS7 6201 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS11 6205 pp -- int.Intact: MI:0914(association)
RPS14 6208 RPS20 6224 pp -- int.I2D: INTEROLOG, YeastMedium, BioGrid_Yeast
CDC42 998 UBB 7314 pp -- int.I2D: SOURAV_MAPK_HIGH
NFKBIB 4793 UBB 7314 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS15 6209 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
YBX1 4904 SERBP1 26135 pd > reg.ITFP.txt: no annot
RPS9 6203 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS20 6224 RPS23 6228 pp -- int.I2D: YeastMedium, INTEROLOG
NME2 4831 RPS16 6217 pp -- int.Proteinpedia: Mass spectrometry
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
MRPS12 6183 RPS20 6224 pp -- int.I2D: YeastMedium
SKP1 6500 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
RPS6 6194 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS13 6207 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS20 6224 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
YBX1 4904 RPS4X 6191 pp -- int.Intact: MI:0914(association)
RPS11 6205 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS23 6228 pp -- int.I2D: YeastLow, BioGrid_Yeast
RPS24 6229 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS4X 6191 RPS7 6201 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS15A 6210 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPS7 6201 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 WDR46 9277 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS23 6228 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS9 6203 pp -- int.I2D: IntAct
RPS9 6203 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
UBB 7314 WWOX 51741 pp -- int.I2D: BCI, HPRD;
int.HPRD: in vivo
UBB 7314 RNF20 56254 pp -- int.Intact: MI:0220(ubiquitination reaction);
int.I2D: IntAct
MRPS12 6183 RPS15 6209 pp -- int.I2D: YeastMedium
RPS8 6202 SKP1 6500 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS7 6201 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 SKP1 6500 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
RPS4X 6191 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS8 6202 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
SRC 6714 WWOX 51741 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
RPS16 6217 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS20 6224 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastHigh, YeastMedium
MRPL23 6150 MRPS12 6183 pd <> reg.ITFP.txt: no annot
YBX1 4904 RPS8 6202 pp -- int.Intact: MI:0914(association)
RPS13 6207 RPS19 6223 pp -- int.I2D: IntAct_Yeast
RPS20 6224 RPS27A 6233 pp -- int.I2D: YeastLow
RPS4X 6191 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS27A 6233 UBB 7314 pp -- int.I2D: BIND
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
NME2 4831 VIM 7431 pp -- int.HPRD: in vivo
RAN 5901 RPS15 6209 pp -- int.I2D: YeastLow
RPS4X 6191 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS13 6207 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS8 6202 RPS19 6223 pp -- int.I2D: MINT
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RPS8 6202 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS4X 6191 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB1 1315 pp -- int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
RAN 5901 WDR46 9277 pp -- int.I2D: YeastLow
YBX1 4904 MRPL23 6150 pd <> reg.ITFP.txt: no annot
YBX1 4904 MRPL23 6150 pp -- int.Intact: MI:0914(association)
RPS7 6201 WDR46 9277 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS23 6228 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS24 6229 pp -- int.Intact: MI:0914(association)
RPS16 6217 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
HSF1 3297 MAPK8 5599 pp -- int.I2D: HPRD, INNATEDB;
int.HPRD: in vitro, in vivo
RPS3A 6189 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
NFKBIB 4793 SKP1 6500 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vitro
RPS6 6194 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
COPB1 1315 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium;
int.DIP: MI:0915(physical association)
COPA 1314 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS15 6209 RPS16 6217 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS11 6205 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, HPRD, IntAct, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro
RPS3A 6189 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RAN 5901 SPHK2 56848 pp -- int.I2D: IntAct_Yeast, BIND_Yeast, MINT_Yeast, MIPS, YeastLow
CDC5L 988 YBX1 4904 pd <> reg.ITFP.txt: no annot
YBX1 4904 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RPS4X 6191 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS11 6205 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
COPB1 1315 COPB2 9276 pp -- int.I2D: BioGrid
YBX1 4904 RPAP2 79871 pp -- int.I2D: BioGrid
ARCN1 372 COPB1 1315 pp -- int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS;
int.HPRD: in vivo
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS15A 6210 pp -- int.I2D: YeastMedium, INTEROLOG
RPS6 6194 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 RPS3A 6189 pp -- int.I2D: IntAct_Yeast
RPS16 6217 RPS23 6228 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS20 6224 pp -- int.I2D: YeastLow
RPS6 6194 RPS7 6201 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
RPS6 6194 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS29 6235 pp -- int.Intact: MI:0914(association)
CDC5L 988 RPS16 6217 pp -- int.I2D: BioGrid
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
MAPK8 5599 WWOX 51741 pp -- int.I2D: MINT, HPRD;
int.Mint: MI:0915(physical association);
int.HPRD: in vivo, yeast 2-hybrid
RPS8 6202 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS23 6228 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS16 6217 RPS26 6231 pp -- int.I2D: BioGrid_Yeast
RAN 5901 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS15A 6210 RPS27A 6233 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RAN 5901 SKP1 6500 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS11 6205 RPS20 6224 pp -- int.I2D: YeastMedium, INTEROLOG
RPS7 6201 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS6 6194 pp -- int.I2D: BioGrid_Yeast, YeastLow

Related GO terms (566)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit1.40e-392.28e-357.342192139
GO:0019058viral life cycle2.29e-353.75e-315.9942225115
GO:0019083viral transcription2.86e-324.66e-286.288192281
GO:0006415translational termination1.30e-312.13e-276.185192287
GO:0003735structural constituent of ribosome3.14e-315.12e-275.6322124141
GO:0006414translational elongation5.31e-318.67e-276.089192293
GO:0006614SRP-dependent cotranslational protein targeting to membrane5.44e-308.89e-265.9271922104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3.60e-295.88e-255.7951922114
GO:0006413translational initiation6.09e-289.94e-245.5941927131
GO:0006412translation2.34e-263.81e-224.8962129235
GO:0016032viral process5.15e-268.40e-224.0032637540
GO:0016071mRNA metabolic process4.33e-257.06e-214.9012029223
GO:0016070RNA metabolic process3.50e-245.71e-204.7532029247
GO:0005829cytosol5.43e-238.86e-192.34239742562
GO:0044822poly(A) RNA binding2.08e-183.40e-143.00626421078
GO:0010467gene expression3.77e-186.15e-143.4532236669
GO:0044267cellular protein metabolic process8.26e-171.35e-123.6761929495
GO:0015935small ribosomal subunit8.62e-171.41e-127.2928917
GO:0016020membrane1.90e-163.09e-122.46829481746
GO:0005925focal adhesion1.27e-132.07e-093.7551523370
GO:0042274ribosomal small subunit biogenesis4.86e-137.93e-097.3806612
GO:0070062extracellular vesicular exosome1.59e-102.59e-061.83827512516
GO:0048205COPI coating of Golgi vesicle2.50e-104.08e-067.0015613
GO:0030126COPI vesicle coat2.50e-104.08e-067.0015613
GO:0005840ribosome4.26e-106.96e-065.30471059
GO:0061024membrane organization4.34e-107.08e-064.360911146
GO:0006890retrograde vesicle-mediated transport, Golgi to ER1.00e-081.64e-046.0585625
GO:0030529ribonucleoprotein complex4.54e-087.41e-044.35478114
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.53e-074.13e-037.643335
GO:0006364rRNA processing4.03e-076.58e-034.3806896
GO:0000028ribosomal small subunit assembly8.83e-071.44e-027.157337
GO:0005515protein binding1.49e-062.43e-020.92835876127
GO:0005737cytoplasm1.42e-052.32e-011.12326653976
GO:0075733intracellular transport of virus1.68e-052.74e-015.8773317
GO:0006891intra-Golgi vesicle-mediated transport1.68e-052.74e-015.8773317
GO:0000056ribosomal small subunit export from nucleus2.64e-054.32e-017.795223
GO:0036464cytoplasmic ribonucleoprotein granule3.76e-056.14e-015.5053522
GO:0043066negative regulation of apoptotic process4.00e-056.52e-012.622814433
GO:0034146toll-like receptor 5 signaling pathway4.24e-056.92e-014.3574565
GO:0034166toll-like receptor 10 signaling pathway4.24e-056.92e-014.3574565
GO:0030490maturation of SSU-rRNA5.28e-058.61e-017.380224
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway6.01e-059.81e-014.2304571
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway6.01e-059.81e-014.2304571
GO:0034162toll-like receptor 9 signaling pathway6.35e-051.00e+004.2104572
GO:0034134toll-like receptor 2 signaling pathway6.70e-051.00e+004.1904573
GO:0019843rRNA binding7.07e-051.00e+005.2103427
GO:0035666TRIF-dependent toll-like receptor signaling pathway7.85e-051.00e+004.1324576
GO:0005730nucleolus7.91e-051.00e+001.56915361684
GO:0003723RNA binding8.50e-051.00e+002.715710355
GO:0002756MyD88-independent toll-like receptor signaling pathway8.69e-051.00e+004.0944578
GO:0033119negative regulation of RNA splicing8.78e-051.00e+007.058225
GO:0002755MyD88-dependent toll-like receptor signaling pathway9.59e-051.00e+004.0584580
GO:0034138toll-like receptor 3 signaling pathway9.59e-051.00e+004.0584580
GO:0045182translation regulator activity1.31e-041.00e+006.795226
GO:0002181cytoplasmic translation1.31e-041.00e+006.795226
GO:0006886intracellular protein transport1.65e-041.00e+003.26756173
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway1.69e-041.00e+004.7953336
GO:0034142toll-like receptor 4 signaling pathway1.94e-041.00e+003.7954596
GO:0007249I-kappaB kinase/NF-kappaB signaling2.50e-041.00e+004.6073441
GO:0002224toll-like receptor signaling pathway3.16e-041.00e+003.61245109
GO:0007254JNK cascade4.79e-041.00e+004.2923351
GO:0051403stress-activated MAPK cascade5.66e-041.00e+004.2103454
GO:0019082viral protein processing5.72e-041.00e+005.7952212
GO:0032479regulation of type I interferon production6.74e-041.00e+005.6792213
GO:0071398cellular response to fatty acid6.74e-041.00e+005.6792213
GO:0016197endosomal transport6.99e-041.00e+004.1073358
GO:0000086G2/M transition of mitotic cell cycle7.51e-041.00e+003.28246137
GO:0032481positive regulation of type I interferon production8.10e-041.00e+004.0343361
GO:0000082G1/S transition of mitotic cell cycle1.05e-031.00e+003.151411150
GO:0031295T cell costimulation1.06e-031.00e+003.8993367
GO:0019068virion assembly1.17e-031.00e+005.2922217
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.21e-031.00e+003.8353870
GO:0043065positive regulation of apoptotic process1.34e-031.00e+002.60456274
GO:0043005neuron projection1.37e-031.00e+003.04946161
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.42e-031.00e+003.7553874
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.71e-031.00e+003.6613879
GO:0007220Notch receptor processing1.96e-031.00e+004.9202222
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway2.53e-031.00e+004.7362225
GO:0005844polysome2.53e-031.00e+004.7362225
GO:0007173epidermal growth factor receptor signaling pathway2.55e-031.00e+002.80245191
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.74e-031.00e+004.6792226
GO:0005978glycogen biosynthetic process2.74e-031.00e+004.6792226
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity2.74e-031.00e+004.6792226
GO:0001649osteoblast differentiation2.90e-031.00e+003.3953395
GO:2001286regulation of caveolin-mediated endocytosis3.00e-031.00e+008.380111
GO:0071393cellular response to progesterone stimulus3.00e-031.00e+008.380111
GO:0033176proton-transporting V-type ATPase complex3.00e-031.00e+008.380111
GO:0004673protein histidine kinase activity3.00e-031.00e+008.380111
GO:0006669sphinganine-1-phosphate biosynthetic process3.00e-031.00e+008.380111
GO:0022605oogenesis stage3.00e-031.00e+008.380111
GO:0018106peptidyl-histidine phosphorylation3.00e-031.00e+008.380111
GO:0021691cerebellar Purkinje cell layer maturation3.00e-031.00e+008.380111
GO:0071456cellular response to hypoxia3.17e-031.00e+003.3503398
GO:0032480negative regulation of type I interferon production4.14e-031.00e+004.3802232
GO:0097190apoptotic signaling pathway5.08e-031.00e+003.10733116
GO:0000209protein polyubiquitination5.08e-031.00e+003.10737116
GO:0034332adherens junction organization5.21e-031.00e+004.2102436
GO:0003713transcription coactivator activity5.67e-031.00e+002.47946239
GO:0030218erythrocyte differentiation5.79e-031.00e+004.1322238
GO:0008481sphinganine kinase activity6.00e-031.00e+007.380112
GO:0071987WD40-repeat domain binding6.00e-031.00e+007.380112
GO:0060661submandibular salivary gland formation6.00e-031.00e+007.380112
GO:1902255positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator6.00e-031.00e+007.380112
GO:0002762negative regulation of myeloid leukocyte differentiation6.00e-031.00e+007.380112
GO:0017050D-erythro-sphingosine kinase activity6.00e-031.00e+007.380112
GO:0071338positive regulation of hair follicle cell proliferation6.00e-031.00e+007.380112
GO:0072422signal transduction involved in DNA damage checkpoint6.00e-031.00e+007.380112
GO:0010632regulation of epithelial cell migration6.00e-031.00e+007.380112
GO:0090135actin filament branching6.00e-031.00e+007.380112
GO:0060265positive regulation of respiratory burst involved in inflammatory response6.00e-031.00e+007.380112
GO:0051092positive regulation of NF-kappaB transcription factor activity6.25e-031.00e+002.99933125
GO:0007219Notch signaling pathway6.25e-031.00e+002.99934125
GO:0007179transforming growth factor beta receptor signaling pathway6.97e-031.00e+002.94234130
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway7.37e-031.00e+003.9532243
GO:0000122negative regulation of transcription from RNA polymerase II promoter8.06e-031.00e+001.76369589
GO:0010641positive regulation of platelet-derived growth factor receptor signaling pathway8.98e-031.00e+006.795113
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding8.98e-031.00e+006.795113
GO:0003161cardiac conduction system development8.98e-031.00e+006.795113
GO:0051154negative regulation of striated muscle cell differentiation8.98e-031.00e+006.795113
GO:0090045positive regulation of deacetylase activity8.98e-031.00e+006.795113
GO:0035033histone deacetylase regulator activity8.98e-031.00e+006.795113
GO:2000017positive regulation of determination of dorsal identity8.98e-031.00e+006.795113
GO:0051683establishment of Golgi localization8.98e-031.00e+006.795123
GO:0006670sphingosine metabolic process8.98e-031.00e+006.795113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity8.98e-031.00e+006.795113
GO:0033146regulation of intracellular estrogen receptor signaling pathway8.98e-031.00e+006.795113
GO:0004705JUN kinase activity8.98e-031.00e+006.795113
GO:0060266negative regulation of respiratory burst involved in inflammatory response8.98e-031.00e+006.795113
GO:0048011neurotrophin TRK receptor signaling pathway8.99e-031.00e+002.28745273
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling9.93e-031.00e+002.75533148
GO:0045087innate immune response9.94e-031.00e+001.698611616
GO:0010628positive regulation of gene expression1.01e-021.00e+002.74634149
GO:0042981regulation of apoptotic process1.05e-021.00e+002.72637151
GO:0030666endocytic vesicle membrane1.14e-021.00e+003.6252254
GO:003068690S preribosome1.20e-021.00e+006.380114
GO:0034191apolipoprotein A-I receptor binding1.20e-021.00e+006.380114
GO:0007000nucleolus organization1.20e-021.00e+006.380124
GO:0009301snRNA transcription1.20e-021.00e+006.380114
GO:0070940dephosphorylation of RNA polymerase II C-terminal domain1.20e-021.00e+006.380114
GO:0032463negative regulation of protein homooligomerization1.20e-021.00e+006.380114
GO:0051902negative regulation of mitochondrial depolarization1.20e-021.00e+006.380114
GO:0060020Bergmann glial cell differentiation1.20e-021.00e+006.380114
GO:0031062positive regulation of histone methylation1.20e-021.00e+006.380114
GO:0060684epithelial-mesenchymal cell signaling1.20e-021.00e+006.380114
GO:0070851growth factor receptor binding1.20e-021.00e+006.380114
GO:0051835positive regulation of synapse structural plasticity1.20e-021.00e+006.380114
GO:0090231regulation of spindle checkpoint1.20e-021.00e+006.380114
GO:0072384organelle transport along microtubule1.20e-021.00e+006.380124
GO:0007258JUN phosphorylation1.20e-021.00e+006.380114
GO:0048664neuron fate determination1.20e-021.00e+006.380114
GO:0033503HULC complex1.20e-021.00e+006.380114
GO:0005198structural molecule activity1.20e-021.00e+002.65235159
GO:0045682regulation of epidermis development1.20e-021.00e+006.380114
GO:0031063regulation of histone deacetylation1.20e-021.00e+006.380114
GO:0031467Cul7-RING ubiquitin ligase complex1.20e-021.00e+006.380114
GO:0000055ribosomal large subunit export from nucleus1.20e-021.00e+006.380114
GO:0008543fibroblast growth factor receptor signaling pathway1.20e-021.00e+002.65233159
GO:0033625positive regulation of integrin activation1.20e-021.00e+006.380114
GO:0009991response to extracellular stimulus1.20e-021.00e+006.380114
GO:0038095Fc-epsilon receptor signaling pathway1.46e-021.00e+002.54733171
GO:2000641regulation of early endosome to late endosome transport1.49e-021.00e+006.058115
GO:0070934CRD-mediated mRNA stabilization1.49e-021.00e+006.058115
GO:0036336dendritic cell migration1.49e-021.00e+006.058115
GO:0035088establishment or maintenance of apical/basal cell polarity1.49e-021.00e+006.058115
GO:0051385response to mineralocorticoid1.49e-021.00e+006.058115
GO:1902188positive regulation of viral release from host cell1.49e-021.00e+006.058115
GO:0097300programmed necrotic cell death1.49e-021.00e+006.058115
GO:0031256leading edge membrane1.49e-021.00e+006.058115
GO:0008420CTD phosphatase activity1.49e-021.00e+006.058115
GO:0071803positive regulation of podosome assembly1.49e-021.00e+006.058115
GO:0046834lipid phosphorylation1.49e-021.00e+006.058115
GO:0006417regulation of translation1.53e-021.00e+003.4022463
GO:0019901protein kinase binding1.54e-021.00e+002.05849320
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.58e-021.00e+003.3802264
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.63e-021.00e+003.3572665
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.63e-021.00e+003.3572665
GO:0005882intermediate filament1.68e-021.00e+003.3352366
GO:0071260cellular response to mechanical stimulus1.68e-021.00e+003.3352366
GO:0003682chromatin binding1.77e-021.00e+001.99644334
GO:0050847progesterone receptor signaling pathway1.79e-021.00e+005.795116
GO:0007143female meiotic division1.79e-021.00e+005.795116
GO:0002309T cell proliferation involved in immune response1.79e-021.00e+005.795116
GO:0004704NF-kappaB-inducing kinase activity1.79e-021.00e+005.795116
GO:0045056transcytosis1.79e-021.00e+005.795116
GO:0060789hair follicle placode formation1.79e-021.00e+005.795116
GO:0048554positive regulation of metalloenzyme activity1.79e-021.00e+005.795116
GO:0050792regulation of viral process1.79e-021.00e+005.795116
GO:0019215intermediate filament binding1.79e-021.00e+005.795116
GO:0070937CRD-mediated mRNA stability complex1.79e-021.00e+005.795116
GO:0000974Prp19 complex1.79e-021.00e+005.795116
GO:0071204histone pre-mRNA 3'end processing complex1.79e-021.00e+005.795116
GO:0006924activation-induced cell death of T cells1.79e-021.00e+005.795126
GO:0003697single-stranded DNA binding1.82e-021.00e+003.2712469
GO:0018105peptidyl-serine phosphorylation1.82e-021.00e+003.2712569
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.03e-021.00e+003.1902673
GO:0003729mRNA binding2.03e-021.00e+003.1902373
GO:0010447response to acidic pH2.08e-021.00e+005.572117
GO:0009142nucleoside triphosphate biosynthetic process2.08e-021.00e+005.572117
GO:0060136embryonic process involved in female pregnancy2.08e-021.00e+005.572117
GO:0043497regulation of protein heterodimerization activity2.08e-021.00e+005.572117
GO:0050658RNA transport2.08e-021.00e+005.572117
GO:0048027mRNA 5'-UTR binding2.08e-021.00e+005.572117
GO:0007097nuclear migration2.08e-021.00e+005.572127
GO:0061512protein localization to cilium2.08e-021.00e+005.572117
GO:0003334keratinocyte development2.08e-021.00e+005.572117
GO:0051988regulation of attachment of spindle microtubules to kinetochore2.08e-021.00e+005.572117
GO:0034101erythrocyte homeostasis2.08e-021.00e+005.572117
GO:0010907positive regulation of glucose metabolic process2.08e-021.00e+005.572117
GO:0030157pancreatic juice secretion2.08e-021.00e+005.572117
GO:0000930gamma-tubulin complex2.08e-021.00e+005.572117
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.24e-021.00e+003.1132677
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.24e-021.00e+003.1132477
GO:0007229integrin-mediated signaling pathway2.29e-021.00e+003.0942278
GO:0039702viral budding via host ESCRT complex2.38e-021.00e+005.380118
GO:0006183GTP biosynthetic process2.38e-021.00e+005.380118
GO:0043114regulation of vascular permeability2.38e-021.00e+005.380118
GO:0045124regulation of bone resorption2.38e-021.00e+005.380118
GO:0051489regulation of filopodium assembly2.38e-021.00e+005.380118
GO:0033523histone H2B ubiquitination2.38e-021.00e+005.380118
GO:0007172signal complex assembly2.38e-021.00e+005.380118
GO:0010629negative regulation of gene expression2.40e-021.00e+003.0582280
GO:0071222cellular response to lipopolysaccharide2.46e-021.00e+003.0402481
GO:0016591DNA-directed RNA polymerase II, holoenzyme2.67e-021.00e+005.210119
GO:0038061NIK/NF-kappaB signaling2.67e-021.00e+005.210119
GO:0071732cellular response to nitric oxide2.67e-021.00e+005.210119
GO:0006241CTP biosynthetic process2.67e-021.00e+005.210119
GO:0014075response to amine2.67e-021.00e+005.210119
GO:0006228UTP biosynthetic process2.67e-021.00e+005.210119
GO:0090136epithelial cell-cell adhesion2.67e-021.00e+005.210129
GO:0047497mitochondrion transport along microtubule2.67e-021.00e+005.210119
GO:0046628positive regulation of insulin receptor signaling pathway2.67e-021.00e+005.210119
GO:0050852T cell receptor signaling pathway2.87e-021.00e+002.9202288
GO:0045618positive regulation of keratinocyte differentiation2.96e-021.00e+005.0581110
GO:0032040small-subunit processome2.96e-021.00e+005.0581110
GO:0070307lens fiber cell development2.96e-021.00e+005.0581110
GO:0005798Golgi-associated vesicle2.96e-021.00e+005.0581110
GO:0031274positive regulation of pseudopodium assembly2.96e-021.00e+005.0581210
GO:0022407regulation of cell-cell adhesion2.96e-021.00e+005.0581110
GO:0060047heart contraction2.96e-021.00e+005.0581110
GO:0008284positive regulation of cell proliferation2.97e-021.00e+001.76547392
GO:0000187activation of MAPK activity2.99e-021.00e+002.8882390
GO:0000278mitotic cell cycle3.12e-021.00e+001.743416398
GO:0007067mitotic nuclear division3.20e-021.00e+002.11337231
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.24e-021.00e+002.8252794
GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity3.25e-021.00e+004.9201111
GO:0051895negative regulation of focal adhesion assembly3.25e-021.00e+004.9201111
GO:0045120pronucleus3.25e-021.00e+004.9201111
GO:2000573positive regulation of DNA biosynthetic process3.25e-021.00e+004.9201211
GO:0051272positive regulation of cellular component movement3.25e-021.00e+004.9201111
GO:0045109intermediate filament organization3.25e-021.00e+004.9201111
GO:0060065uterus development3.25e-021.00e+004.9201111
GO:0010390histone monoubiquitination3.25e-021.00e+004.9201111
GO:0035518histone H2A monoubiquitination3.25e-021.00e+004.9201211
GO:0014002astrocyte development3.25e-021.00e+004.9201111
GO:0005634nucleus3.28e-021.00e+000.53521664828
GO:0061136regulation of proteasomal protein catabolic process3.54e-021.00e+004.7951112
GO:0007051spindle organization3.54e-021.00e+004.7951112
GO:0043149stress fiber assembly3.54e-021.00e+004.7951212
GO:1903543positive regulation of exosomal secretion3.54e-021.00e+004.7951112
GO:1901214regulation of neuron death3.54e-021.00e+004.7951112
GO:0043488regulation of mRNA stability3.83e-021.00e+004.6791113
GO:0031929TOR signaling3.83e-021.00e+004.6791113
GO:0005662DNA replication factor A complex3.83e-021.00e+004.6791113
GO:0060444branching involved in mammary gland duct morphogenesis3.83e-021.00e+004.6791113
GO:0004143diacylglycerol kinase activity3.83e-021.00e+004.6791113
GO:0035371microtubule plus-end4.12e-021.00e+004.5721114
GO:0031333negative regulation of protein complex assembly4.12e-021.00e+004.5721114
GO:0050662coenzyme binding4.12e-021.00e+004.5721114
GO:0017016Ras GTPase binding4.12e-021.00e+004.5721114
GO:0031996thioesterase binding4.12e-021.00e+004.5721114
GO:0006165nucleoside diphosphate phosphorylation4.12e-021.00e+004.5721114
GO:0005815microtubule organizing center4.31e-021.00e+002.59824110
GO:0005654nucleoplasm4.38e-021.00e+001.0907261095
GO:0048477oogenesis4.41e-021.00e+004.4731115
GO:0030131clathrin adaptor complex4.41e-021.00e+004.4731115
GO:0030225macrophage differentiation4.41e-021.00e+004.4731115
GO:0003951NAD+ kinase activity4.41e-021.00e+004.4731115
GO:0004550nucleoside diphosphate kinase activity4.41e-021.00e+004.4731115
GO:0048821erythrocyte development4.41e-021.00e+004.4731215
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand4.41e-021.00e+004.4731115
GO:0031369translation initiation factor binding4.41e-021.00e+004.4731215
GO:0051233spindle midzone4.41e-021.00e+004.4731215
GO:0005762mitochondrial large ribosomal subunit4.41e-021.00e+004.4731115
GO:0014911positive regulation of smooth muscle cell migration4.70e-021.00e+004.3801116
GO:0048037cofactor binding4.70e-021.00e+004.3801116
GO:0042176regulation of protein catabolic process4.70e-021.00e+004.3801416
GO:2000811negative regulation of anoikis4.70e-021.00e+004.3801116
GO:0005212structural constituent of eye lens4.70e-021.00e+004.3801116
GO:0006006glucose metabolic process4.96e-021.00e+002.48524119
GO:0002548monocyte chemotaxis4.99e-021.00e+004.2921117
GO:0030742GTP-dependent protein binding4.99e-021.00e+004.2921117
GO:0070064proline-rich region binding5.27e-021.00e+004.2101118
GO:0004709MAP kinase kinase kinase activity5.27e-021.00e+004.2101118
GO:0031954positive regulation of protein autophosphorylation5.27e-021.00e+004.2101118
GO:0015949nucleobase-containing small molecule interconversion5.27e-021.00e+004.2101118
GO:0043015gamma-tubulin binding5.27e-021.00e+004.2101218
GO:0090316positive regulation of intracellular protein transport5.27e-021.00e+004.2101118
GO:0006259DNA metabolic process5.56e-021.00e+004.1321119
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process5.56e-021.00e+004.1321119
GO:0007088regulation of mitosis5.56e-021.00e+004.1321119
GO:0017134fibroblast growth factor binding5.56e-021.00e+004.1321219
GO:0045453bone resorption5.56e-021.00e+004.1321119
GO:0031667response to nutrient levels5.56e-021.00e+004.1321119
GO:0032148activation of protein kinase B activity5.84e-021.00e+004.0581120
GO:0051090regulation of sequence-specific DNA binding transcription factor activity5.84e-021.00e+004.0581220
GO:0043473pigmentation5.84e-021.00e+004.0581220
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator5.84e-021.00e+004.0581120
GO:0043393regulation of protein binding5.84e-021.00e+004.0581220
GO:0009615response to virus5.97e-021.00e+002.33524132
GO:0007369gastrulation6.12e-021.00e+003.9871121
GO:0005689U12-type spliceosomal complex6.12e-021.00e+003.9871221
GO:0046847filopodium assembly6.12e-021.00e+003.9871121
GO:0051881regulation of mitochondrial membrane potential6.12e-021.00e+003.9871121
GO:2001243negative regulation of intrinsic apoptotic signaling pathway6.40e-021.00e+003.9201122
GO:0046686response to cadmium ion6.40e-021.00e+003.9201122
GO:0033574response to testosterone6.40e-021.00e+003.9201122
GO:0001106RNA polymerase II transcription corepressor activity6.40e-021.00e+003.9201122
GO:0031435mitogen-activated protein kinase kinase kinase binding6.40e-021.00e+003.9201122
GO:0007052mitotic spindle organization6.40e-021.00e+003.9201122
GO:1900026positive regulation of substrate adhesion-dependent cell spreading6.69e-021.00e+003.8561123
GO:0071944cell periphery6.69e-021.00e+003.8561123
GO:0045787positive regulation of cell cycle6.69e-021.00e+003.8561223
GO:0002040sprouting angiogenesis6.69e-021.00e+003.8561123
GO:0051017actin filament bundle assembly6.69e-021.00e+003.8561123
GO:0001892embryonic placenta development6.69e-021.00e+003.8561123
GO:0051297centrosome organization6.69e-021.00e+003.8561223
GO:0008286insulin receptor signaling pathway6.95e-021.00e+002.21024144
GO:0005761mitochondrial ribosome6.97e-021.00e+003.7951124
GO:0007163establishment or maintenance of cell polarity6.97e-021.00e+003.7951224
GO:0051602response to electrical stimulus6.97e-021.00e+003.7951124
GO:0006611protein export from nucleus7.25e-021.00e+003.7361125
GO:0031519PcG protein complex7.25e-021.00e+003.7361125
GO:0050715positive regulation of cytokine secretion7.25e-021.00e+003.7361125
GO:0048705skeletal system morphogenesis7.25e-021.00e+003.7361125
GO:0045859regulation of protein kinase activity7.53e-021.00e+003.6791126
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway7.53e-021.00e+003.6791126
GO:0030148sphingolipid biosynthetic process7.53e-021.00e+003.6791126
GO:0043231intracellular membrane-bounded organelle7.75e-021.00e+001.59033332
GO:0051149positive regulation of muscle cell differentiation7.80e-021.00e+003.6251227
GO:0032720negative regulation of tumor necrosis factor production7.80e-021.00e+003.6251127
GO:2001238positive regulation of extrinsic apoptotic signaling pathway7.80e-021.00e+003.6251127
GO:0031424keratinization7.80e-021.00e+003.6251127
GO:0001103RNA polymerase II repressing transcription factor binding7.80e-021.00e+003.6251127
GO:0030331estrogen receptor binding7.80e-021.00e+003.6251127
GO:0045184establishment of protein localization7.80e-021.00e+003.6251227
GO:0031069hair follicle morphogenesis7.80e-021.00e+003.6251127
GO:0010008endosome membrane8.06e-021.00e+002.08522157
GO:0032467positive regulation of cytokinesis8.08e-021.00e+003.5721128
GO:0042626ATPase activity, coupled to transmembrane movement of substances8.08e-021.00e+003.5721128
GO:0005813centrosome8.14e-021.00e+001.56039339
GO:0031252cell leading edge8.36e-021.00e+003.5221329
GO:0019005SCF ubiquitin ligase complex8.36e-021.00e+003.5221129
GO:0003730mRNA 3'-UTR binding8.36e-021.00e+003.5221129
GO:0034605cellular response to heat8.36e-021.00e+003.5221129
GO:0072686mitotic spindle8.36e-021.00e+003.5221129
GO:0008022protein C-terminus binding8.42e-021.00e+002.04924161
GO:0010977negative regulation of neuron projection development8.63e-021.00e+003.4731230
GO:0051262protein tetramerization8.63e-021.00e+003.4731130
GO:0046875ephrin receptor binding8.63e-021.00e+003.4731230
GO:0042169SH2 domain binding8.63e-021.00e+003.4731130
GO:0031647regulation of protein stability8.63e-021.00e+003.4731130
GO:0040018positive regulation of multicellular organism growth8.63e-021.00e+003.4731130
GO:0010494cytoplasmic stress granule8.63e-021.00e+003.4731230
GO:0000398mRNA splicing, via spliceosome8.78e-021.00e+002.01322165
GO:0070555response to interleukin-18.91e-021.00e+003.4261131
GO:0007093mitotic cell cycle checkpoint8.91e-021.00e+003.4261231
GO:0034220ion transmembrane transport8.96e-021.00e+001.99622167
GO:0006915apoptotic process9.15e-021.00e+001.22249571
GO:0005739mitochondrion9.16e-021.00e+000.9346101046
GO:0033572transferrin transport9.18e-021.00e+003.3801132
GO:0015992proton transport9.18e-021.00e+003.3801132
GO:0051219phosphoprotein binding9.18e-021.00e+003.3801432
GO:0032091negative regulation of protein binding9.45e-021.00e+003.3351133
GO:0005158insulin receptor binding9.45e-021.00e+003.3351233
GO:0033077T cell differentiation in thymus9.45e-021.00e+003.3351133
GO:0048812neuron projection morphogenesis9.45e-021.00e+003.3351133
GO:0045944positive regulation of transcription from RNA polymerase II promoter9.48e-021.00e+001.038511811
GO:0001890placenta development9.73e-021.00e+003.2921134
GO:0097110scaffold protein binding9.73e-021.00e+003.2921134
GO:0042692muscle cell differentiation9.73e-021.00e+003.2921234
GO:0051701interaction with host9.73e-021.00e+003.2921134
GO:0004672protein kinase activity9.98e-021.00e+001.90424178
GO:0007205protein kinase C-activating G-protein coupled receptor signaling pathway1.00e-011.00e+003.2501135
GO:0071333cellular response to glucose stimulus1.00e-011.00e+003.2501235
GO:2001237negative regulation of extrinsic apoptotic signaling pathway1.00e-011.00e+003.2501135
GO:0019904protein domain specific binding1.03e-011.00e+001.88023181
GO:0030178negative regulation of Wnt signaling pathway1.03e-011.00e+003.2101136
GO:0071560cellular response to transforming growth factor beta stimulus1.03e-011.00e+003.2101136
GO:0016301kinase activity1.05e-011.00e+003.1701237
GO:0006367transcription initiation from RNA polymerase II promoter1.05e-011.00e+001.85625184
GO:0018107peptidyl-threonine phosphorylation1.05e-011.00e+003.1701137
GO:0032880regulation of protein localization1.05e-011.00e+003.1701137
GO:0001568blood vessel development1.08e-011.00e+003.1321238
GO:0050681androgen receptor binding1.08e-011.00e+003.1321238
GO:0030049muscle filament sliding1.08e-011.00e+003.1321238
GO:0097191extrinsic apoptotic signaling pathway1.08e-011.00e+003.1321338
GO:0045740positive regulation of DNA replication1.08e-011.00e+003.1321138
GO:0090382phagosome maturation1.08e-011.00e+003.1321138
GO:0051781positive regulation of cell division1.11e-011.00e+003.0941139
GO:0032092positive regulation of protein binding1.11e-011.00e+003.0941139
GO:0021766hippocampus development1.11e-011.00e+003.0941339
GO:0042542response to hydrogen peroxide1.13e-011.00e+003.0581140
GO:0070301cellular response to hydrogen peroxide1.16e-011.00e+003.0221141
GO:0030521androgen receptor signaling pathway1.16e-011.00e+003.0221341
GO:0045785positive regulation of cell adhesion1.16e-011.00e+003.0221141
GO:0005902microvillus1.19e-011.00e+002.9871142
GO:0004715non-membrane spanning protein tyrosine kinase activity1.19e-011.00e+002.9871142
GO:0007286spermatid development1.24e-011.00e+002.9201144
GO:0005080protein kinase C binding1.24e-011.00e+002.9201144
GO:0003924GTPase activity1.24e-011.00e+001.71426203
GO:0034613cellular protein localization1.24e-011.00e+002.9201244
GO:0009411response to UV1.27e-011.00e+002.8881245
GO:0051591response to cAMP1.27e-011.00e+002.8881145
GO:0044297cell body1.29e-011.00e+002.8561146
GO:0043525positive regulation of neuron apoptotic process1.29e-011.00e+002.8561246
GO:0045727positive regulation of translation1.29e-011.00e+002.8561146
GO:0021762substantia nigra development1.29e-011.00e+002.8561246
GO:0043406positive regulation of MAP kinase activity1.32e-011.00e+002.8251147
GO:0006921cellular component disassembly involved in execution phase of apoptosis1.32e-011.00e+002.8251147
GO:0008344adult locomotory behavior1.32e-011.00e+002.8251247
GO:0006950response to stress1.35e-011.00e+002.7951148
GO:0019003GDP binding1.35e-011.00e+002.7951148
GO:0005070SH3/SH2 adaptor activity1.37e-011.00e+002.7651149
GO:0045111intermediate filament cytoskeleton1.37e-011.00e+002.7651149
GO:0005765lysosomal membrane1.39e-011.00e+001.61222218
GO:0001948glycoprotein binding1.40e-011.00e+002.7361250
GO:0035690cellular response to drug1.40e-011.00e+002.7361350
GO:0007030Golgi organization1.40e-011.00e+002.7361350
GO:0006184GTP catabolic process1.41e-011.00e+001.59826220
GO:0090263positive regulation of canonical Wnt signaling pathway1.42e-011.00e+002.7071151
GO:0030900forebrain development1.42e-011.00e+002.7071151
GO:0008202steroid metabolic process1.45e-011.00e+002.6791152
GO:0006952defense response1.48e-011.00e+002.6521153
GO:0030175filopodium1.48e-011.00e+002.6521253
GO:0003725double-stranded RNA binding1.50e-011.00e+002.6251254
GO:0009612response to mechanical stimulus1.50e-011.00e+002.6251154
GO:0000186activation of MAPKK activity1.50e-011.00e+002.6251154
GO:0050679positive regulation of epithelial cell proliferation1.50e-011.00e+002.6251254
GO:0019221cytokine-mediated signaling pathway1.52e-011.00e+001.53425230
GO:0097193intrinsic apoptotic signaling pathway1.53e-011.00e+002.5981255
GO:0002039p53 binding1.53e-011.00e+002.5981155
GO:0046330positive regulation of JNK cascade1.53e-011.00e+002.5981155
GO:0005793endoplasmic reticulum-Golgi intermediate compartment1.58e-011.00e+002.5471157
GO:0006879cellular iron ion homeostasis1.58e-011.00e+002.5471257
GO:0005643nuclear pore1.63e-011.00e+002.4971159
GO:0010976positive regulation of neuron projection development1.65e-011.00e+002.4731260
GO:0033138positive regulation of peptidyl-serine phosphorylation1.68e-011.00e+002.4491161
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.70e-011.00e+002.4261162
GO:0000151ubiquitin ligase complex1.73e-011.00e+002.4021163
GO:0005901caveola1.73e-011.00e+002.4021163
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process1.73e-011.00e+002.4021263
GO:0032869cellular response to insulin stimulus1.75e-011.00e+002.3801264
GO:0043025neuronal cell body1.77e-011.00e+001.39125254
GO:0016491oxidoreductase activity1.78e-011.00e+002.3571165
GO:0045893positive regulation of transcription, DNA-templated1.79e-011.00e+001.03738487
GO:0004842ubiquitin-protein transferase activity1.79e-011.00e+001.38023256
GO:0030141secretory granule1.83e-011.00e+002.3141267
GO:0006665sphingolipid metabolic process1.85e-011.00e+002.2921168
GO:0006281DNA repair1.88e-011.00e+001.33525264
GO:0035264multicellular organism growth1.90e-011.00e+002.2501170
GO:0042393histone binding1.93e-011.00e+002.2301171
GO:0001503ossification1.93e-011.00e+002.2301271
GO:0000165MAPK cascade1.95e-011.00e+002.2101272
GO:0000166nucleotide binding1.97e-011.00e+001.29222272
GO:0000785chromatin1.97e-011.00e+002.1901273
GO:0055086nucleobase-containing small molecule metabolic process1.97e-011.00e+002.1901273
GO:0005975carbohydrate metabolic process1.99e-011.00e+001.28223274
GO:0042826histone deacetylase binding2.00e-011.00e+002.1701174
GO:0055085transmembrane transport2.00e-011.00e+000.95933514
GO:0007265Ras protein signal transduction2.02e-011.00e+002.1511375
GO:0051897positive regulation of protein kinase B signaling2.02e-011.00e+002.1511175
GO:0060070canonical Wnt signaling pathway2.02e-011.00e+002.1511275
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding2.02e-011.00e+002.1511175
GO:0044325ion channel binding2.07e-011.00e+002.1131377
GO:0048471perinuclear region of cytoplasm2.07e-011.00e+000.93439523
GO:0071013catalytic step 2 spliceosome2.12e-011.00e+002.0761179
GO:0019899enzyme binding2.14e-011.00e+001.21025288
GO:0031902late endosome membrane2.14e-011.00e+002.0581180
GO:0007264small GTPase mediated signal transduction2.16e-011.00e+001.20027290
GO:0045177apical part of cell2.19e-011.00e+002.0221182
GO:0001726ruffle2.19e-011.00e+002.0221182
GO:0004713protein tyrosine kinase activity2.19e-011.00e+002.0221182
GO:0030336negative regulation of cell migration2.21e-011.00e+002.0051283
GO:0005929cilium2.24e-011.00e+001.9871284
GO:0005179hormone activity2.24e-011.00e+001.9871184
GO:0043234protein complex2.27e-011.00e+001.15129300
GO:0042593glucose homeostasis2.35e-011.00e+001.9041189
GO:0042384cilium assembly2.38e-011.00e+001.8881290
GO:0005777peroxisome2.38e-011.00e+001.8881190
GO:0000922spindle pole2.40e-011.00e+001.8721591
GO:0003690double-stranded DNA binding2.40e-011.00e+001.8721291
GO:0016337single organismal cell-cell adhesion2.42e-011.00e+001.8561292
GO:0006928cellular component movement2.42e-011.00e+001.8561492
GO:0042470melanosome2.42e-011.00e+001.8561292
GO:0005200structural constituent of cytoskeleton2.45e-011.00e+001.8411693
GO:0005770late endosome2.47e-011.00e+001.8251194
GO:0005178integrin binding2.54e-011.00e+001.7801197
GO:0007411axon guidance2.57e-011.00e+001.02723327
GO:0005525GTP binding2.59e-011.00e+001.02226328
GO:0008283cell proliferation2.62e-011.00e+001.00924331
GO:0014069postsynaptic density2.74e-011.00e+001.65213106
GO:0030496midbody2.80e-011.00e+001.61214109
GO:0070374positive regulation of ERK1 and ERK2 cascade2.82e-011.00e+001.59811110
GO:0050900leukocyte migration2.85e-011.00e+001.58511111
GO:0020037heme binding2.85e-011.00e+001.58511111
GO:0015630microtubule cytoskeleton2.87e-011.00e+001.57214112
GO:0032496response to lipopolysaccharide3.08e-011.00e+001.44911122
GO:0051056regulation of small GTPase mediated signal transduction3.10e-011.00e+001.43713123
GO:0005794Golgi apparatus3.10e-011.00e+000.62038650
GO:0006511ubiquitin-dependent protein catabolic process3.18e-011.00e+001.39113127
GO:0030036actin cytoskeleton organization3.23e-011.00e+001.36913129
GO:0030027lamellipodium3.25e-011.00e+001.35713130
GO:0046983protein dimerization activity3.27e-011.00e+001.34613131
GO:0018108peptidyl-tyrosine phosphorylation3.31e-011.00e+001.32411133
GO:0006351transcription, DNA-templated3.39e-011.00e+000.3346171585
GO:0016055Wnt signaling pathway3.47e-011.00e+001.24013141
GO:0000139Golgi membrane3.47e-011.00e+000.70727408
GO:0044281small molecule metabolic process3.48e-011.00e+000.3635161295
GO:0005911cell-cell junction3.49e-011.00e+001.23012142
GO:0006366transcription from RNA polymerase II promoter3.66e-011.00e+000.64823425
GO:0046777protein autophosphorylation3.80e-011.00e+001.07611158
GO:0005524ATP binding3.84e-011.00e+000.2995191354
GO:0003700sequence-specific DNA binding transcription factor activity3.91e-011.00e+000.41839748
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding3.98e-011.00e+000.98714168
GO:0007420brain development4.05e-011.00e+000.95313172
GO:0007596blood coagulation4.08e-011.00e+000.52225464
GO:0006468protein phosphorylation4.11e-011.00e+000.51226467
GO:0016607nuclear speck4.11e-011.00e+000.92912175
GO:0031965nuclear membrane4.13e-011.00e+000.92012176
GO:0007049cell cycle4.14e-011.00e+000.91214177
GO:0031625ubiquitin protein ligase binding4.20e-011.00e+000.88814180
GO:0005764lysosome4.23e-011.00e+000.87212182
GO:0006355regulation of transcription, DNA-templated4.25e-011.00e+000.2714101104
GO:0042802identical protein binding4.36e-011.00e+000.44024491
GO:0030168platelet activation4.62e-011.00e+000.70014205
GO:0001701in utero embryonic development4.70e-011.00e+000.66512210
GO:0004871signal transducer activity4.80e-011.00e+000.62511216
GO:0016874ligase activity4.92e-011.00e+000.57212224
GO:0008380RNA splicing5.05e-011.00e+000.52215232
GO:0030425dendrite5.17e-011.00e+000.47313240
GO:0007165signal transduction5.49e-011.00e+000.07337950
GO:0005102receptor binding5.56e-011.00e+000.31412268
GO:0007283spermatogenesis5.67e-011.00e+000.27112276
GO:0042493response to drug5.83e-011.00e+000.21012288
GO:0016567protein ubiquitination5.96e-011.00e+000.15613299
GO:0005743mitochondrial inner membrane5.98e-011.00e+000.15111300
GO:0006955immune response6.04e-011.00e+000.12712305
GO:0005856cytoskeleton6.11e-011.00e+000.09916311
GO:0004674protein serine/threonine kinase activity6.12e-011.00e+000.09416312
GO:0035556intracellular signal transduction6.18e-011.00e+000.07115317
GO:0005575cellular_component6.24e-011.00e+000.04912322
GO:0030154cell differentiation6.27e-011.00e+000.03513325
GO:0005886plasma membrane6.35e-011.00e+00-0.0898242834
GO:0007275multicellular organismal development6.48e-011.00e+00-0.04712344
GO:0015031protein transport6.62e-011.00e+00-0.10014357
GO:0008285negative regulation of cell proliferation6.72e-011.00e+00-0.14013367
GO:0007155cell adhesion6.89e-011.00e+00-0.20513384
GO:0045892negative regulation of transcription, DNA-templated7.25e-011.00e+00-0.34812424
GO:0008150biological_process7.53e-011.00e+00-0.46313459
GO:0055114oxidation-reduction process7.70e-011.00e+00-0.53012481
GO:0003677DNA binding7.83e-011.00e+00-0.4353141351
GO:0046872metal ion binding8.28e-011.00e+00-0.5523141465
GO:0008270zinc ion binding8.39e-011.00e+00-0.680271067
GO:0005783endoplasmic reticulum8.46e-011.00e+00-0.87316610
GO:0042803protein homodimerization activity8.49e-011.00e+00-0.88914617
GO:0005615extracellular space9.56e-011.00e+00-1.600131010