meta-reg-snw-1432

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
int-snw-56848 tai-screen-luciferase 6.375 2.94e-136 3.59e-07 2.58e-03 24 19
reg-snw-1432 tai-screen-luciferase 4.670 5.00e-24 6.11e-04 9.80e-04 9 5
int-snw-6150 tai-screen-luciferase 6.375 3.15e-136 3.60e-07 2.59e-03 23 17
int-snw-4831 tai-screen-luciferase 6.314 3.38e-133 5.36e-07 3.08e-03 24 20
int-snw-51741 tai-screen-luciferase 6.174 2.67e-126 1.32e-06 4.54e-03 24 19
tai-screen-luciferase-meta-reg-snw-1432 subnetwork

Genes (51)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS20 6224 22-4.7576.314153Yes-
RPS8 6202 33-5.5457.555234--
MAPK8 5599 28-4.4036.468153--
CHMP2A 27243 33-9.0377.55541YesYes
RPS15 6209 30-5.0407.011116Yes-
COPA 1314 48-9.3955.672340YesYes
RNF20 56254 28-4.5646.17418--
RPS29 6235 17-8.3866.59729--
HSF1 3297 46-4.1795.027209-Yes
MAPK14 1432 52.0794.67032--
SRC 6714 28-2.8066.174419Yes-
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
RPS16 6217 38-5.4444.880205--
CDC42 998 44-6.9604.707276YesYes
RPS11 6205 44-6.5887.555175Yes-
NME2 4831 24-3.0344.32553--
RPS6 6194 44-5.6038.046217Yes-
MRPS12 6183 35-5.4215.516341Yes-
YBX1 4904 24-3.0335.516296--
RAN 5901 38-3.8094.325258YesYes
UBB 7314 30-4.2896.428147--
MAP3K14 9020 15-3.4626.375138-Yes
COPB1 1315 39-6.2219.063118YesYes
SERBP1 26135 35-4.6125.516106-Yes
RPS23 6228 21-4.4856.375118Yes-
RPS13 6207 43-6.5897.555174Yes-
CDC5L 988 34-3.4195.672155--
ZNF672 79894 5-2.6814.67098--
RPS24 6229 46-7.0348.389217Yes-
VIM 7431 18-3.7606.428246--
RPAP2 79871 153.1116.37549--
TCERG1 10915 28-3.8086.17458Yes-
RPS9 6203 45-7.1277.555140Yes-
RPS3A 6189 19-4.6477.189166Yes-
RPS4X 6191 44-6.7477.555263Yes-
COPZ1 22818 48-8.3019.06313YesYes
ATP6V1D 51382 30-4.1317.286149--
RPS15A 6210 36-5.4137.555177Yes-
WDR46 9277 31-4.2904.226101YesYes
WWOX 51741 28-2.4486.17438--
RPS7 6201 15-4.3826.375165Yes-
RPS27A 6233 45-5.6318.389344Yes-
RPS14 6208 23-4.8037.011204Yes-
RPS19 6223 21-4.7014.752102Yes-
SKP1 6500 26-3.7506.413203--
NFKBIB 4793 28-3.9786.17478--
SPHK2 56848 17-3.0106.37537--
RPS26 6231 43-7.4788.04660Yes-
ARCN1 372 48-8.2329.063118YesYes
MRPL23 6150 15-2.5716.3759--

Interactions (183)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
CDC42 998 RPS27A 6233 pp -- int.I2D: SOURAV_MAPK_HIGH
RPS20 6224 RPS26 6231 pp -- int.I2D: YeastLow
RPS4X 6191 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS27A 6233 SKP1 6500 pp -- int.I2D: BioGrid_Yeast, YeastLow
YBX1 4904 RPS23 6228 pp -- int.Intact: MI:0914(association)
NME2 4831 RPS19 6223 pp -- int.Proteinpedia: Mass spectrometry
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
RPS20 6224 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS13 6207 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, HPRD, IntAct, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro
VIM 7431 SERBP1 26135 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, HPRD, BioGrid, MINT, StelzlHigh;
int.Mint: MI:0915(physical association);
int.HPRD: yeast 2-hybrid
RPS11 6205 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS11 6205 RPS19 6223 pp -- int.I2D: IntAct_Yeast
RPS7 6201 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
TCERG1 10915 WWOX 51741 pp -- int.I2D: BioGrid, MINT, Pawson1;
int.Mint: MI:0915(physical association)
RPS3A 6189 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
SRC 6714 CKAP5 9793 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
YBX1 4904 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
YBX1 4904 RPS7 6201 pp -- int.Intact: MI:0914(association)
ARCN1 372 RAN 5901 pp -- int.I2D: YeastLow
RPS15 6209 RPS23 6228 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS7 6201 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
HSF1 3297 ZNF672 79894 pd <> reg.ITFP.txt: no annot
YBX1 4904 RPS11 6205 pp -- int.Intact: MI:0914(association)
RPS14 6208 RPS20 6224 pp -- int.I2D: INTEROLOG, YeastMedium, BioGrid_Yeast
CDC42 998 UBB 7314 pp -- int.I2D: SOURAV_MAPK_HIGH
NFKBIB 4793 UBB 7314 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct
RPS15 6209 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
YBX1 4904 SERBP1 26135 pd > reg.ITFP.txt: no annot
RPS9 6203 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS20 6224 RPS23 6228 pp -- int.I2D: YeastMedium, INTEROLOG
NME2 4831 RPS16 6217 pp -- int.Proteinpedia: Mass spectrometry
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
MRPS12 6183 RPS20 6224 pp -- int.I2D: YeastMedium
SKP1 6500 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
RPS6 6194 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS13 6207 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS20 6224 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
YBX1 4904 RPS4X 6191 pp -- int.Intact: MI:0914(association)
RPS11 6205 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS23 6228 pp -- int.I2D: YeastLow, BioGrid_Yeast
RPS24 6229 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS4X 6191 RPS7 6201 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS15A 6210 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
CDC5L 988 MAPK14 1432 pd > reg.ITFP.txt: no annot
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPS7 6201 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 WDR46 9277 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
MAPK14 1432 YBX1 4904 pd < reg.ITFP.txt: no annot
RPS3A 6189 RPS23 6228 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS9 6203 pp -- int.I2D: IntAct
RPS9 6203 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
COPA 1314 MAPK14 1432 pd > reg.ITFP.txt: no annot
COPA 1314 MAPK14 1432 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
UBB 7314 WWOX 51741 pp -- int.I2D: BCI, HPRD;
int.HPRD: in vivo
UBB 7314 RNF20 56254 pp -- int.Intact: MI:0220(ubiquitination reaction);
int.I2D: IntAct
MRPS12 6183 RPS15 6209 pp -- int.I2D: YeastMedium
RPS8 6202 SKP1 6500 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS7 6201 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 SKP1 6500 pp -- int.I2D: MINT;
int.Mint: MI:0915(physical association)
RPS4X 6191 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS8 6202 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
SRC 6714 WWOX 51741 pp -- int.I2D: HPRD;
int.HPRD: in vitro, in vivo
RPS16 6217 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS20 6224 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastHigh, YeastMedium
MRPL23 6150 MRPS12 6183 pd <> reg.ITFP.txt: no annot
MAPK14 1432 HSF1 3297 pd < reg.ITFP.txt: no annot
YBX1 4904 RPS8 6202 pp -- int.Intact: MI:0914(association)
RPS13 6207 RPS19 6223 pp -- int.I2D: IntAct_Yeast
RPS20 6224 RPS27A 6233 pp -- int.I2D: YeastLow
RPS4X 6191 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
MAPK14 1432 MAPK8 5599 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RPS27A 6233 UBB 7314 pp -- int.I2D: BIND
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
NME2 4831 VIM 7431 pp -- int.HPRD: in vivo
RAN 5901 RPS15 6209 pp -- int.I2D: YeastLow
RPS4X 6191 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS13 6207 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS8 6202 RPS19 6223 pp -- int.I2D: MINT
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RPS8 6202 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS4X 6191 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB1 1315 pp -- int.I2D: BioGrid, BioGrid_Yeast, BIND_Yeast, IntAct_Yeast, MINT_Yeast, Krogan_Core, YeastHigh
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 ATP6V1D 51382 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS20 6224 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
RAN 5901 WDR46 9277 pp -- int.I2D: YeastLow
YBX1 4904 MRPL23 6150 pd <> reg.ITFP.txt: no annot
YBX1 4904 MRPL23 6150 pp -- int.Intact: MI:0914(association)
RPS7 6201 WDR46 9277 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS23 6228 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS24 6229 pp -- int.Intact: MI:0914(association)
RPS16 6217 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
HSF1 3297 MAPK8 5599 pp -- int.I2D: HPRD, INNATEDB;
int.HPRD: in vitro, in vivo
RPS3A 6189 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
MAPK14 1432 ZNF672 79894 pd < reg.ITFP.txt: no annot
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
NFKBIB 4793 SKP1 6500 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vitro
RPS6 6194 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
COPB1 1315 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, Tarassov_PCA, YeastMedium;
int.DIP: MI:0915(physical association)
COPA 1314 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS15 6209 RPS16 6217 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS11 6205 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: BCI, HPRD, IntAct, MINT;
int.Mint: MI:0915(physical association);
int.HPRD: in vitro
RPS3A 6189 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
HSF1 3297 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RAN 5901 SPHK2 56848 pp -- int.I2D: IntAct_Yeast, BIND_Yeast, MINT_Yeast, MIPS, YeastLow
CDC5L 988 YBX1 4904 pd <> reg.ITFP.txt: no annot
YBX1 4904 MRPS12 6183 pd <> reg.ITFP.txt: no annot
RPS4X 6191 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS11 6205 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
COPB1 1315 COPB2 9276 pp -- int.I2D: BioGrid
YBX1 4904 RPAP2 79871 pp -- int.I2D: BioGrid
ARCN1 372 COPB1 1315 pp -- int.I2D: BCI, BioGrid, BioGrid_Yeast, IntAct_Yeast, INTEROLOG, MINT_Yeast, YeastHigh, BIND, BIND_Yeast, HPRD, Krogan_Core, MIPS;
int.HPRD: in vivo
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS15A 6210 pp -- int.I2D: YeastMedium, INTEROLOG
RPS6 6194 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 RPS3A 6189 pp -- int.I2D: IntAct_Yeast
RPS16 6217 RPS23 6228 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS20 6224 pp -- int.I2D: YeastLow
RPS6 6194 RPS7 6201 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
RPS6 6194 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
YBX1 4904 RPS29 6235 pp -- int.Intact: MI:0914(association)
CDC5L 988 RPS16 6217 pp -- int.I2D: BioGrid
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
MAPK8 5599 WWOX 51741 pp -- int.I2D: MINT, HPRD;
int.Mint: MI:0915(physical association);
int.HPRD: in vivo, yeast 2-hybrid
RPS8 6202 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS7 6201 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS23 6228 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS16 6217 RPS26 6231 pp -- int.I2D: BioGrid_Yeast
RAN 5901 ATP6V1D 51382 pp -- int.I2D: YeastLow
RPS15A 6210 RPS27A 6233 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RAN 5901 SKP1 6500 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 MAP3K14 9020 pp -- int.Intact: MI:0915(physical association);
int.I2D: IntAct, MINT;
int.Mint: MI:0915(physical association)
RPS11 6205 RPS20 6224 pp -- int.I2D: YeastMedium, INTEROLOG
COPB1 1315 MAPK14 1432 pp -- int.I2D: IntAct_Mouse, MINT_Mouse
RPS7 6201 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS6 6194 pp -- int.I2D: BioGrid_Yeast, YeastLow

Related GO terms (600)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit3.59e-395.86e-357.285192139
GO:0019058viral life cycle7.13e-351.16e-305.9362225115
GO:0019083viral transcription7.29e-321.19e-276.230192281
GO:0006415translational termination3.33e-315.43e-276.127192287
GO:0003735structural constituent of ribosome9.07e-311.48e-265.5752124141
GO:0006414translational elongation1.35e-302.21e-266.031192293
GO:0006614SRP-dependent cotranslational protein targeting to membrane1.39e-292.26e-255.8701922104
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay9.16e-291.49e-245.7371922114
GO:0006413translational initiation1.55e-272.52e-235.5371927131
GO:0016071mRNA metabolic process2.16e-263.52e-224.9132129223
GO:0006412translation6.68e-261.09e-214.8382129235
GO:0016070RNA metabolic process1.95e-253.18e-214.7662129247
GO:0016032viral process2.06e-253.36e-213.9462637540
GO:0005829cytosol4.14e-236.75e-192.32140742562
GO:0010467gene expression5.69e-199.29e-153.4602336669
GO:0044822poly(A) RNA binding7.78e-181.27e-132.94826421078
GO:0015935small ribosomal subunit1.22e-161.98e-127.2358917
GO:0044267cellular protein metabolic process2.01e-163.27e-123.6191929495
GO:0016020membrane8.44e-161.38e-112.41029481746
GO:0005925focal adhesion2.46e-134.02e-093.6981523370
GO:0042274ribosomal small subunit biogenesis6.26e-131.02e-087.3226612
GO:0070062extracellular vesicular exosome8.15e-111.33e-061.83228512516
GO:0048205COPI coating of Golgi vesicle3.08e-105.02e-066.9445613
GO:0030126COPI vesicle coat3.08e-105.02e-066.9445613
GO:0005840ribosome5.71e-109.33e-065.24771059
GO:0061024membrane organization6.32e-101.03e-054.302911146
GO:0006890retrograde vesicle-mediated transport, Golgi to ER1.23e-082.01e-046.0005625
GO:0030529ribonucleoprotein complex6.05e-089.88e-044.29678114
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)2.86e-074.67e-037.585335
GO:0006364rRNA processing5.14e-078.40e-034.3226896
GO:0000028ribosomal small subunit assembly9.97e-071.63e-027.100337
GO:0005515protein binding1.66e-062.72e-020.91136876127
GO:0034146toll-like receptor 5 signaling pathway1.75e-062.85e-024.6225565
GO:0034166toll-like receptor 10 signaling pathway1.75e-062.85e-024.6225565
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway2.72e-064.43e-024.4945571
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway2.72e-064.43e-024.4945571
GO:0034162toll-like receptor 9 signaling pathway2.91e-064.75e-024.4745572
GO:0034134toll-like receptor 2 signaling pathway3.12e-065.09e-024.4545573
GO:0035666TRIF-dependent toll-like receptor signaling pathway3.81e-066.22e-024.3965576
GO:0002756MyD88-independent toll-like receptor signaling pathway4.33e-067.07e-024.3595578
GO:0002755MyD88-dependent toll-like receptor signaling pathway4.91e-068.01e-024.3225580
GO:0034138toll-like receptor 3 signaling pathway4.91e-068.01e-024.3225580
GO:0005737cytoplasm1.03e-051.68e-011.12027653976
GO:0034142toll-like receptor 4 signaling pathway1.20e-051.96e-014.0595596
GO:0075733intracellular transport of virus1.90e-053.09e-015.8203317
GO:0006891intra-Golgi vesicle-mediated transport1.90e-053.09e-015.8203317
GO:0002224toll-like receptor signaling pathway2.23e-053.64e-013.87655109
GO:0051403stress-activated MAPK cascade2.38e-053.89e-014.5674454
GO:0000056ribosomal small subunit export from nucleus2.87e-054.68e-017.737223
GO:0036464cytoplasmic ribonucleoprotein granule4.25e-056.93e-015.4483522
GO:0043066negative regulation of apoptotic process5.39e-058.79e-012.564814433
GO:0030490maturation of SSU-rRNA5.72e-059.34e-017.322224
GO:0019843rRNA binding7.97e-051.00e+005.1523427
GO:0033119negative regulation of RNA splicing9.52e-051.00e+007.000225
GO:0003723RNA binding1.10e-041.00e+002.658710355
GO:0005730nucleolus1.31e-041.00e+001.51115361684
GO:0045182translation regulator activity1.42e-041.00e+006.737226
GO:0002181cytoplasmic translation1.42e-041.00e+006.737226
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway1.91e-041.00e+004.7373336
GO:0006886intracellular protein transport2.00e-041.00e+003.20956173
GO:0007249I-kappaB kinase/NF-kappaB signaling2.82e-041.00e+004.5493441
GO:0007254JNK cascade5.39e-041.00e+004.2353351
GO:0019082viral protein processing6.19e-041.00e+005.7372212
GO:0032479regulation of type I interferon production7.30e-041.00e+005.6222213
GO:0071398cellular response to fatty acid7.30e-041.00e+005.6222213
GO:0016197endosomal transport7.86e-041.00e+004.0493358
GO:0000086G2/M transition of mitotic cell cycle8.75e-041.00e+003.22446137
GO:0032481positive regulation of type I interferon production9.11e-041.00e+003.9763361
GO:0031295T cell costimulation1.20e-031.00e+003.8413367
GO:0000082G1/S transition of mitotic cell cycle1.22e-031.00e+003.093411150
GO:0019068virion assembly1.26e-031.00e+005.2352217
GO:0018105peptidyl-serine phosphorylation1.30e-031.00e+003.7983569
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.36e-031.00e+003.7783870
GO:0048011neurotrophin TRK receptor signaling pathway1.58e-031.00e+002.55155273
GO:0043005neuron projection1.59e-031.00e+002.99146161
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.59e-031.00e+003.6983874
GO:0043065positive regulation of apoptotic process1.61e-031.00e+002.54656274
GO:0051090regulation of sequence-specific DNA binding transcription factor activity1.75e-031.00e+005.0002220
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.92e-031.00e+003.6033879
GO:0071222cellular response to lipopolysaccharide2.07e-031.00e+003.5673481
GO:0007220Notch receptor processing2.12e-031.00e+004.8632222
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway2.74e-031.00e+004.6782225
GO:0005844polysome2.74e-031.00e+004.6782225
GO:0000187activation of MAPK activity2.79e-031.00e+003.4153390
GO:0045087innate immune response2.88e-031.00e+001.863711616
GO:0007173epidermal growth factor receptor signaling pathway2.96e-031.00e+002.74545191
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia2.97e-031.00e+004.6222226
GO:0005978glycogen biosynthetic process2.97e-031.00e+004.6222226
GO:0043552positive regulation of phosphatidylinositol 3-kinase activity2.97e-031.00e+004.6222226
GO:2001286regulation of caveolin-mediated endocytosis3.12e-031.00e+008.322111
GO:0071393cellular response to progesterone stimulus3.12e-031.00e+008.322111
GO:0033176proton-transporting V-type ATPase complex3.12e-031.00e+008.322111
GO:0014835myoblast differentiation involved in skeletal muscle regeneration3.12e-031.00e+008.322111
GO:0004673protein histidine kinase activity3.12e-031.00e+008.322111
GO:0006669sphinganine-1-phosphate biosynthetic process3.12e-031.00e+008.322111
GO:0022605oogenesis stage3.12e-031.00e+008.322111
GO:0018106peptidyl-histidine phosphorylation3.12e-031.00e+008.322111
GO:0021691cerebellar Purkinje cell layer maturation3.12e-031.00e+008.322111
GO:0038066p38MAPK cascade3.12e-031.00e+008.322111
GO:0051149positive regulation of muscle cell differentiation3.20e-031.00e+004.5672227
GO:0001649osteoblast differentiation3.25e-031.00e+003.3373395
GO:0071456cellular response to hypoxia3.55e-031.00e+003.2923398
GO:0032480negative regulation of type I interferon production4.47e-031.00e+004.3222232
GO:0042692muscle cell differentiation5.04e-031.00e+004.2352234
GO:0034332adherens junction organization5.64e-031.00e+004.1522436
GO:0097190apoptotic signaling pathway5.68e-031.00e+003.04933116
GO:0000209protein polyubiquitination5.68e-031.00e+003.04937116
GO:0006006glucose metabolic process6.10e-031.00e+003.01234119
GO:0008481sphinganine kinase activity6.24e-031.00e+007.322112
GO:0071987WD40-repeat domain binding6.24e-031.00e+007.322112
GO:0060661submandibular salivary gland formation6.24e-031.00e+007.322112
GO:1902255positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator6.24e-031.00e+007.322112
GO:0002762negative regulation of myeloid leukocyte differentiation6.24e-031.00e+007.322112
GO:0017050D-erythro-sphingosine kinase activity6.24e-031.00e+007.322112
GO:0071338positive regulation of hair follicle cell proliferation6.24e-031.00e+007.322112
GO:0072422signal transduction involved in DNA damage checkpoint6.24e-031.00e+007.322112
GO:0010632regulation of epithelial cell migration6.24e-031.00e+007.322112
GO:0090135actin filament branching6.24e-031.00e+007.322112
GO:0060265positive regulation of respiratory burst involved in inflammatory response6.24e-031.00e+007.322112
GO:0030218erythrocyte differentiation6.26e-031.00e+004.0742238
GO:0003713transcription coactivator activity6.54e-031.00e+002.42146239
GO:0051092positive regulation of NF-kappaB transcription factor activity6.99e-031.00e+002.94133125
GO:0007219Notch signaling pathway6.99e-031.00e+002.94134125
GO:0007179transforming growth factor beta receptor signaling pathway7.78e-031.00e+002.88534130
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway7.97e-031.00e+003.8962243
GO:0010641positive regulation of platelet-derived growth factor receptor signaling pathway9.35e-031.00e+006.737113
GO:0001162RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding9.35e-031.00e+006.737113
GO:0003161cardiac conduction system development9.35e-031.00e+006.737113
GO:0051154negative regulation of striated muscle cell differentiation9.35e-031.00e+006.737113
GO:0090045positive regulation of deacetylase activity9.35e-031.00e+006.737113
GO:0035033histone deacetylase regulator activity9.35e-031.00e+006.737113
GO:2000017positive regulation of determination of dorsal identity9.35e-031.00e+006.737113
GO:0051683establishment of Golgi localization9.35e-031.00e+006.737123
GO:0006670sphingosine metabolic process9.35e-031.00e+006.737113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity9.35e-031.00e+006.737113
GO:0033146regulation of intracellular estrogen receptor signaling pathway9.35e-031.00e+006.737113
GO:0090400stress-induced premature senescence9.35e-031.00e+006.737113
GO:0004705JUN kinase activity9.35e-031.00e+006.737113
GO:0060266negative regulation of respiratory burst involved in inflammatory response9.35e-031.00e+006.737113
GO:0000122negative regulation of transcription from RNA polymerase II promoter9.77e-031.00e+001.70569589
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling1.11e-021.00e+002.69833148
GO:0010628positive regulation of gene expression1.13e-021.00e+002.68834149
GO:0042981regulation of apoptotic process1.17e-021.00e+002.66937151
GO:003068690S preribosome1.24e-021.00e+006.322114
GO:0034191apolipoprotein A-I receptor binding1.24e-021.00e+006.322114
GO:0007000nucleolus organization1.24e-021.00e+006.322124
GO:0030666endocytic vesicle membrane1.24e-021.00e+003.5672254
GO:0009301snRNA transcription1.24e-021.00e+006.322114
GO:0070940dephosphorylation of RNA polymerase II C-terminal domain1.24e-021.00e+006.322114
GO:0032463negative regulation of protein homooligomerization1.24e-021.00e+006.322114
GO:0051902negative regulation of mitochondrial depolarization1.24e-021.00e+006.322114
GO:0060020Bergmann glial cell differentiation1.24e-021.00e+006.322114
GO:0031062positive regulation of histone methylation1.24e-021.00e+006.322114
GO:0060684epithelial-mesenchymal cell signaling1.24e-021.00e+006.322114
GO:0070851growth factor receptor binding1.24e-021.00e+006.322114
GO:0051835positive regulation of synapse structural plasticity1.24e-021.00e+006.322114
GO:0090231regulation of spindle checkpoint1.24e-021.00e+006.322114
GO:0072384organelle transport along microtubule1.24e-021.00e+006.322124
GO:0007258JUN phosphorylation1.24e-021.00e+006.322114
GO:0048664neuron fate determination1.24e-021.00e+006.322114
GO:0033503HULC complex1.24e-021.00e+006.322114
GO:0045682regulation of epidermis development1.24e-021.00e+006.322114
GO:0031063regulation of histone deacetylation1.24e-021.00e+006.322114
GO:0031467Cul7-RING ubiquitin ligase complex1.24e-021.00e+006.322114
GO:0000055ribosomal large subunit export from nucleus1.24e-021.00e+006.322114
GO:0033625positive regulation of integrin activation1.24e-021.00e+006.322114
GO:0009991response to extracellular stimulus1.24e-021.00e+006.322114
GO:0005634nucleus1.34e-021.00e+000.60823664828
GO:0005198structural molecule activity1.34e-021.00e+002.59435159
GO:0008543fibroblast growth factor receptor signaling pathway1.34e-021.00e+002.59433159
GO:2000641regulation of early endosome to late endosome transport1.55e-021.00e+006.000115
GO:0070934CRD-mediated mRNA stabilization1.55e-021.00e+006.000115
GO:0036336dendritic cell migration1.55e-021.00e+006.000115
GO:0035088establishment or maintenance of apical/basal cell polarity1.55e-021.00e+006.000115
GO:0051385response to mineralocorticoid1.55e-021.00e+006.000115
GO:1902188positive regulation of viral release from host cell1.55e-021.00e+006.000115
GO:0097300programmed necrotic cell death1.55e-021.00e+006.000115
GO:0031256leading edge membrane1.55e-021.00e+006.000115
GO:0008420CTD phosphatase activity1.55e-021.00e+006.000115
GO:0051525NFAT protein binding1.55e-021.00e+006.000115
GO:1901741positive regulation of myoblast fusion1.55e-021.00e+006.000115
GO:0071803positive regulation of podosome assembly1.55e-021.00e+006.000115
GO:0046834lipid phosphorylation1.55e-021.00e+006.000115
GO:0038095Fc-epsilon receptor signaling pathway1.63e-021.00e+002.48933171
GO:0006417regulation of translation1.66e-021.00e+003.3452463
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.71e-021.00e+003.3222264
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.76e-021.00e+003.3002665
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.76e-021.00e+003.3002665
GO:0019901protein kinase binding1.76e-021.00e+002.00049320
GO:0005882intermediate filament1.81e-021.00e+003.2782366
GO:0071260cellular response to mechanical stimulus1.81e-021.00e+003.2782366
GO:0050847progesterone receptor signaling pathway1.86e-021.00e+005.737116
GO:0007143female meiotic division1.86e-021.00e+005.737116
GO:0002309T cell proliferation involved in immune response1.86e-021.00e+005.737116
GO:0004704NF-kappaB-inducing kinase activity1.86e-021.00e+005.737116
GO:0045056transcytosis1.86e-021.00e+005.737116
GO:0060789hair follicle placode formation1.86e-021.00e+005.737116
GO:0048554positive regulation of metalloenzyme activity1.86e-021.00e+005.737116
GO:0050792regulation of viral process1.86e-021.00e+005.737116
GO:0019215intermediate filament binding1.86e-021.00e+005.737116
GO:0070937CRD-mediated mRNA stability complex1.86e-021.00e+005.737116
GO:0000974Prp19 complex1.86e-021.00e+005.737116
GO:0071204histone pre-mRNA 3'end processing complex1.86e-021.00e+005.737116
GO:0006924activation-induced cell death of T cells1.86e-021.00e+005.737126
GO:0005654nucleoplasm1.94e-021.00e+001.2258261095
GO:0003697single-stranded DNA binding1.97e-021.00e+003.2132469
GO:0003682chromatin binding2.02e-021.00e+001.93844334
GO:0010447response to acidic pH2.17e-021.00e+005.515117
GO:0009142nucleoside triphosphate biosynthetic process2.17e-021.00e+005.515117
GO:0060136embryonic process involved in female pregnancy2.17e-021.00e+005.515117
GO:0043497regulation of protein heterodimerization activity2.17e-021.00e+005.515117
GO:0050658RNA transport2.17e-021.00e+005.515117
GO:0048027mRNA 5'-UTR binding2.17e-021.00e+005.515117
GO:0007097nuclear migration2.17e-021.00e+005.515127
GO:0061512protein localization to cilium2.17e-021.00e+005.515117
GO:0003334keratinocyte development2.17e-021.00e+005.515117
GO:0051988regulation of attachment of spindle microtubules to kinetochore2.17e-021.00e+005.515117
GO:0034101erythrocyte homeostasis2.17e-021.00e+005.515117
GO:0010907positive regulation of glucose metabolic process2.17e-021.00e+005.515117
GO:0030157pancreatic juice secretion2.17e-021.00e+005.515117
GO:0000930gamma-tubulin complex2.17e-021.00e+005.515117
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent2.18e-021.00e+003.1322673
GO:0003729mRNA binding2.18e-021.00e+003.1322373
GO:0007265Ras protein signal transduction2.30e-021.00e+003.0932375
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I2.41e-021.00e+003.0552677
GO:0038096Fc-gamma receptor signaling pathway involved in phagocytosis2.41e-021.00e+003.0552477
GO:0007229integrin-mediated signaling pathway2.47e-021.00e+003.0372278
GO:0039702viral budding via host ESCRT complex2.47e-021.00e+005.322118
GO:0006183GTP biosynthetic process2.47e-021.00e+005.322118
GO:0043114regulation of vascular permeability2.47e-021.00e+005.322118
GO:0045124regulation of bone resorption2.47e-021.00e+005.322118
GO:0051489regulation of filopodium assembly2.47e-021.00e+005.322118
GO:0033523histone H2B ubiquitination2.47e-021.00e+005.322118
GO:0007172signal complex assembly2.47e-021.00e+005.322118
GO:0010831positive regulation of myotube differentiation2.47e-021.00e+005.322118
GO:0010629negative regulation of gene expression2.59e-021.00e+003.0002280
GO:0016591DNA-directed RNA polymerase II, holoenzyme2.78e-021.00e+005.152119
GO:0038061NIK/NF-kappaB signaling2.78e-021.00e+005.152119
GO:0071732cellular response to nitric oxide2.78e-021.00e+005.152119
GO:0006241CTP biosynthetic process2.78e-021.00e+005.152119
GO:0014075response to amine2.78e-021.00e+005.152119
GO:0006228UTP biosynthetic process2.78e-021.00e+005.152119
GO:0090136epithelial cell-cell adhesion2.78e-021.00e+005.152129
GO:0047497mitochondrion transport along microtubule2.78e-021.00e+005.152119
GO:0046628positive regulation of insulin receptor signaling pathway2.78e-021.00e+005.152119
GO:0032495response to muramyl dipeptide2.78e-021.00e+005.152119
GO:0045618positive regulation of keratinocyte differentiation3.08e-021.00e+005.0001110
GO:0032040small-subunit processome3.08e-021.00e+005.0001110
GO:0070307lens fiber cell development3.08e-021.00e+005.0001110
GO:0005798Golgi-associated vesicle3.08e-021.00e+005.0001110
GO:0031274positive regulation of pseudopodium assembly3.08e-021.00e+005.0001210
GO:0022407regulation of cell-cell adhesion3.08e-021.00e+005.0001110
GO:0060047heart contraction3.08e-021.00e+005.0001110
GO:0050852T cell receptor signaling pathway3.09e-021.00e+002.8632288
GO:0006915apoptotic process3.23e-021.00e+001.48759571
GO:0000922spindle pole3.29e-021.00e+002.8142591
GO:0006928cellular component movement3.35e-021.00e+002.7982492
GO:0008284positive regulation of cell proliferation3.38e-021.00e+001.70747392
GO:0045737positive regulation of cyclin-dependent protein serine/threonine kinase activity3.39e-021.00e+004.8631111
GO:0051895negative regulation of focal adhesion assembly3.39e-021.00e+004.8631111
GO:0045120pronucleus3.39e-021.00e+004.8631111
GO:2000573positive regulation of DNA biosynthetic process3.39e-021.00e+004.8631211
GO:0051272positive regulation of cellular component movement3.39e-021.00e+004.8631111
GO:0045663positive regulation of myoblast differentiation3.39e-021.00e+004.8631111
GO:0045109intermediate filament organization3.39e-021.00e+004.8631111
GO:0060065uterus development3.39e-021.00e+004.8631111
GO:0019395fatty acid oxidation3.39e-021.00e+004.8631111
GO:0004707MAP kinase activity3.39e-021.00e+004.8631111
GO:0010390histone monoubiquitination3.39e-021.00e+004.8631111
GO:0035518histone H2A monoubiquitination3.39e-021.00e+004.8631211
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway3.39e-021.00e+004.8631111
GO:0014002astrocyte development3.39e-021.00e+004.8631111
GO:0042770signal transduction in response to DNA damage3.39e-021.00e+004.8631111
GO:0002474antigen processing and presentation of peptide antigen via MHC class I3.49e-021.00e+002.7672794
GO:0000278mitotic cell cycle3.54e-021.00e+001.685416398
GO:0007067mitotic nuclear division3.54e-021.00e+002.05537231
GO:0061136regulation of proteasomal protein catabolic process3.69e-021.00e+004.7371112
GO:0007051spindle organization3.69e-021.00e+004.7371112
GO:00709353'-UTR-mediated mRNA stabilization3.69e-021.00e+004.7371112
GO:0051146striated muscle cell differentiation3.69e-021.00e+004.7371212
GO:0043149stress fiber assembly3.69e-021.00e+004.7371212
GO:1903543positive regulation of exosomal secretion3.69e-021.00e+004.7371112
GO:1901214regulation of neuron death3.69e-021.00e+004.7371112
GO:0045944positive regulation of transcription from RNA polymerase II promoter3.98e-021.00e+001.243611811
GO:0043488regulation of mRNA stability3.99e-021.00e+004.6221113
GO:0031929TOR signaling3.99e-021.00e+004.6221113
GO:0004708MAP kinase kinase activity3.99e-021.00e+004.6221113
GO:0005662DNA replication factor A complex3.99e-021.00e+004.6221113
GO:0060444branching involved in mammary gland duct morphogenesis3.99e-021.00e+004.6221113
GO:0004143diacylglycerol kinase activity3.99e-021.00e+004.6221113
GO:0035371microtubule plus-end4.29e-021.00e+004.5151114
GO:0031333negative regulation of protein complex assembly4.29e-021.00e+004.5151114
GO:0050662coenzyme binding4.29e-021.00e+004.5151114
GO:0017016Ras GTPase binding4.29e-021.00e+004.5151114
GO:0031996thioesterase binding4.29e-021.00e+004.5151114
GO:0006165nucleoside diphosphate phosphorylation4.29e-021.00e+004.5151114
GO:0005739mitochondrion4.29e-021.00e+001.0997101046
GO:0048477oogenesis4.59e-021.00e+004.4151115
GO:0030131clathrin adaptor complex4.59e-021.00e+004.4151115
GO:0030225macrophage differentiation4.59e-021.00e+004.4151115
GO:0003951NAD+ kinase activity4.59e-021.00e+004.4151115
GO:0004550nucleoside diphosphate kinase activity4.59e-021.00e+004.4151115
GO:0048821erythrocyte development4.59e-021.00e+004.4151215
GO:0042307positive regulation of protein import into nucleus4.59e-021.00e+004.4151215
GO:2001241positive regulation of extrinsic apoptotic signaling pathway in absence of ligand4.59e-021.00e+004.4151115
GO:0031369translation initiation factor binding4.59e-021.00e+004.4151215
GO:0051233spindle midzone4.59e-021.00e+004.4151215
GO:0005762mitochondrial large ribosomal subunit4.59e-021.00e+004.4151115
GO:0005815microtubule organizing center4.63e-021.00e+002.54124110
GO:0014911positive regulation of smooth muscle cell migration4.89e-021.00e+004.3221116
GO:0048037cofactor binding4.89e-021.00e+004.3221116
GO:0042176regulation of protein catabolic process4.89e-021.00e+004.3221416
GO:2000811negative regulation of anoikis4.89e-021.00e+004.3221116
GO:0005212structural constituent of eye lens4.89e-021.00e+004.3221116
GO:0002548monocyte chemotaxis5.18e-021.00e+004.2351117
GO:0043536positive regulation of blood vessel endothelial cell migration5.18e-021.00e+004.2351117
GO:0030742GTP-dependent protein binding5.18e-021.00e+004.2351117
GO:0070064proline-rich region binding5.48e-021.00e+004.1521118
GO:0004709MAP kinase kinase kinase activity5.48e-021.00e+004.1521118
GO:0031954positive regulation of protein autophosphorylation5.48e-021.00e+004.1521118
GO:0015949nucleobase-containing small molecule interconversion5.48e-021.00e+004.1521118
GO:0043015gamma-tubulin binding5.48e-021.00e+004.1521218
GO:0090316positive regulation of intracellular protein transport5.48e-021.00e+004.1521118
GO:0006259DNA metabolic process5.78e-021.00e+004.0741119
GO:0031146SCF-dependent proteasomal ubiquitin-dependent protein catabolic process5.78e-021.00e+004.0741119
GO:0007088regulation of mitosis5.78e-021.00e+004.0741119
GO:0017134fibroblast growth factor binding5.78e-021.00e+004.0741219
GO:0045453bone resorption5.78e-021.00e+004.0741119
GO:0031667response to nutrient levels5.78e-021.00e+004.0741119
GO:0032148activation of protein kinase B activity6.07e-021.00e+004.0001120
GO:0001502cartilage condensation6.07e-021.00e+004.0001120
GO:0035924cellular response to vascular endothelial growth factor stimulus6.07e-021.00e+004.0001120
GO:0043473pigmentation6.07e-021.00e+004.0001220
GO:0072332intrinsic apoptotic signaling pathway by p53 class mediator6.07e-021.00e+004.0001120
GO:0043393regulation of protein binding6.07e-021.00e+004.0001220
GO:0048010vascular endothelial growth factor receptor signaling pathway6.36e-021.00e+003.9301121
GO:0045648positive regulation of erythrocyte differentiation6.36e-021.00e+003.9301121
GO:0007369gastrulation6.36e-021.00e+003.9301121
GO:0005689U12-type spliceosomal complex6.36e-021.00e+003.9301221
GO:0046847filopodium assembly6.36e-021.00e+003.9301121
GO:0051881regulation of mitochondrial membrane potential6.36e-021.00e+003.9301121
GO:0009615response to virus6.40e-021.00e+002.27824132
GO:0030316osteoclast differentiation6.66e-021.00e+003.8631122
GO:2001243negative regulation of intrinsic apoptotic signaling pathway6.66e-021.00e+003.8631122
GO:0046686response to cadmium ion6.66e-021.00e+003.8631122
GO:0033574response to testosterone6.66e-021.00e+003.8631122
GO:0001106RNA polymerase II transcription corepressor activity6.66e-021.00e+003.8631122
GO:0031435mitogen-activated protein kinase kinase kinase binding6.66e-021.00e+003.8631122
GO:0007052mitotic spindle organization6.66e-021.00e+003.8631122
GO:1900026positive regulation of substrate adhesion-dependent cell spreading6.95e-021.00e+003.7981123
GO:0071944cell periphery6.95e-021.00e+003.7981123
GO:0045787positive regulation of cell cycle6.95e-021.00e+003.7981223
GO:0002040sprouting angiogenesis6.95e-021.00e+003.7981123
GO:0051017actin filament bundle assembly6.95e-021.00e+003.7981123
GO:0001892embryonic placenta development6.95e-021.00e+003.7981123
GO:0051297centrosome organization6.95e-021.00e+003.7981223
GO:0005761mitochondrial ribosome7.24e-021.00e+003.7371124
GO:0007163establishment or maintenance of cell polarity7.24e-021.00e+003.7371224
GO:0051602response to electrical stimulus7.24e-021.00e+003.7371124
GO:2000379positive regulation of reactive oxygen species metabolic process7.24e-021.00e+003.7371124
GO:0008286insulin receptor signaling pathway7.45e-021.00e+002.15224144
GO:0006611protein export from nucleus7.53e-021.00e+003.6781125
GO:0031519PcG protein complex7.53e-021.00e+003.6781125
GO:0071479cellular response to ionizing radiation7.53e-021.00e+003.6781225
GO:0050715positive regulation of cytokine secretion7.53e-021.00e+003.6781125
GO:0048705skeletal system morphogenesis7.53e-021.00e+003.6781125
GO:0045859regulation of protein kinase activity7.82e-021.00e+003.6221126
GO:1900740positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway7.82e-021.00e+003.6221126
GO:0030148sphingolipid biosynthetic process7.82e-021.00e+003.6221126
GO:0032720negative regulation of tumor necrosis factor production8.11e-021.00e+003.5671127
GO:2001238positive regulation of extrinsic apoptotic signaling pathway8.11e-021.00e+003.5671127
GO:0031424keratinization8.11e-021.00e+003.5671127
GO:0001103RNA polymerase II repressing transcription factor binding8.11e-021.00e+003.5671127
GO:0030331estrogen receptor binding8.11e-021.00e+003.5671127
GO:0045184establishment of protein localization8.11e-021.00e+003.5671227
GO:0031069hair follicle morphogenesis8.11e-021.00e+003.5671127
GO:0032467positive regulation of cytokinesis8.40e-021.00e+003.5151128
GO:0000077DNA damage checkpoint8.40e-021.00e+003.5151128
GO:0042626ATPase activity, coupled to transmembrane movement of substances8.40e-021.00e+003.5151128
GO:0043231intracellular membrane-bounded organelle8.51e-021.00e+001.53233332
GO:0010008endosome membrane8.64e-021.00e+002.02722157
GO:0031252cell leading edge8.68e-021.00e+003.4641329
GO:0019005SCF ubiquitin ligase complex8.68e-021.00e+003.4641129
GO:0003730mRNA 3'-UTR binding8.68e-021.00e+003.4641129
GO:0034605cellular response to heat8.68e-021.00e+003.4641129
GO:0072686mitotic spindle8.68e-021.00e+003.4641129
GO:0031663lipopolysaccharide-mediated signaling pathway8.68e-021.00e+003.4641129
GO:0005813centrosome8.93e-021.00e+001.50239339
GO:0010977negative regulation of neuron projection development8.97e-021.00e+003.4151230
GO:0051262protein tetramerization8.97e-021.00e+003.4151130
GO:0046875ephrin receptor binding8.97e-021.00e+003.4151230
GO:0042169SH2 domain binding8.97e-021.00e+003.4151130
GO:0031647regulation of protein stability8.97e-021.00e+003.4151130
GO:0040018positive regulation of multicellular organism growth8.97e-021.00e+003.4151130
GO:0010494cytoplasmic stress granule8.97e-021.00e+003.4151230
GO:0008022protein C-terminus binding9.01e-021.00e+001.99124161
GO:0070555response to interleukin-19.25e-021.00e+003.3681131
GO:0007093mitotic cell cycle checkpoint9.25e-021.00e+003.3681231
GO:0000398mRNA splicing, via spliceosome9.40e-021.00e+001.95622165
GO:0033572transferrin transport9.54e-021.00e+003.3221132
GO:0002062chondrocyte differentiation9.54e-021.00e+003.3221132
GO:0015992proton transport9.54e-021.00e+003.3221132
GO:0051219phosphoprotein binding9.54e-021.00e+003.3221432
GO:0034220ion transmembrane transport9.59e-021.00e+001.93822167
GO:0032091negative regulation of protein binding9.82e-021.00e+003.2781133
GO:0005158insulin receptor binding9.82e-021.00e+003.2781233
GO:0033077T cell differentiation in thymus9.82e-021.00e+003.2781133
GO:0048812neuron projection morphogenesis9.82e-021.00e+003.2781133
GO:0001890placenta development1.01e-011.00e+003.2351134
GO:0097110scaffold protein binding1.01e-011.00e+003.2351134
GO:0051701interaction with host1.01e-011.00e+003.2351134
GO:0007205protein kinase C-activating G-protein coupled receptor signaling pathway1.04e-011.00e+003.1931135
GO:0071333cellular response to glucose stimulus1.04e-011.00e+003.1931235
GO:2001237negative regulation of extrinsic apoptotic signaling pathway1.04e-011.00e+003.1931135
GO:0030178negative regulation of Wnt signaling pathway1.07e-011.00e+003.1521136
GO:0004672protein kinase activity1.07e-011.00e+001.84624178
GO:0071560cellular response to transforming growth factor beta stimulus1.07e-011.00e+003.1521136
GO:0016301kinase activity1.09e-011.00e+003.1131237
GO:0018107peptidyl-threonine phosphorylation1.09e-011.00e+003.1131137
GO:0032880regulation of protein localization1.09e-011.00e+003.1131137
GO:0019904protein domain specific binding1.10e-011.00e+001.82223181
GO:0001568blood vessel development1.12e-011.00e+003.0741238
GO:0050681androgen receptor binding1.12e-011.00e+003.0741238
GO:0030049muscle filament sliding1.12e-011.00e+003.0741238
GO:0097191extrinsic apoptotic signaling pathway1.12e-011.00e+003.0741338
GO:0045740positive regulation of DNA replication1.12e-011.00e+003.0741138
GO:0090382phagosome maturation1.12e-011.00e+003.0741138
GO:0006367transcription initiation from RNA polymerase II promoter1.13e-011.00e+001.79825184
GO:0051781positive regulation of cell division1.15e-011.00e+003.0371139
GO:0032092positive regulation of protein binding1.15e-011.00e+003.0371139
GO:0021766hippocampus development1.15e-011.00e+003.0371339
GO:0006351transcription, DNA-templated1.17e-011.00e+000.6928171585
GO:0042542response to hydrogen peroxide1.18e-011.00e+003.0001140
GO:0070301cellular response to hydrogen peroxide1.21e-011.00e+002.9641141
GO:0030521androgen receptor signaling pathway1.21e-011.00e+002.9641341
GO:0045785positive regulation of cell adhesion1.21e-011.00e+002.9641141
GO:0007519skeletal muscle tissue development1.21e-011.00e+002.9641141
GO:0005902microvillus1.23e-011.00e+002.9301142
GO:0004715non-membrane spanning protein tyrosine kinase activity1.23e-011.00e+002.9301142
GO:0007286spermatid development1.29e-011.00e+002.8631144
GO:0005080protein kinase C binding1.29e-011.00e+002.8631144
GO:0034613cellular protein localization1.29e-011.00e+002.8631244
GO:0009411response to UV1.32e-011.00e+002.8301245
GO:0003924GTPase activity1.32e-011.00e+001.65726203
GO:0051591response to cAMP1.32e-011.00e+002.8301145
GO:0030168platelet activation1.34e-011.00e+001.64324205
GO:0044297cell body1.34e-011.00e+002.7981146
GO:0043525positive regulation of neuron apoptotic process1.34e-011.00e+002.7981246
GO:0045727positive regulation of translation1.34e-011.00e+002.7981146
GO:0021762substantia nigra development1.34e-011.00e+002.7981246
GO:0043406positive regulation of MAP kinase activity1.37e-011.00e+002.7671147
GO:0006921cellular component disassembly involved in execution phase of apoptosis1.37e-011.00e+002.7671147
GO:0008344adult locomotory behavior1.37e-011.00e+002.7671247
GO:0006950response to stress1.40e-011.00e+002.7371148
GO:0019003GDP binding1.40e-011.00e+002.7371148
GO:0005070SH3/SH2 adaptor activity1.42e-011.00e+002.7071149
GO:0045111intermediate filament cytoskeleton1.42e-011.00e+002.7071149
GO:0001948glycoprotein binding1.45e-011.00e+002.6781250
GO:0035690cellular response to drug1.45e-011.00e+002.6781350
GO:0007030Golgi organization1.45e-011.00e+002.6781350
GO:0005765lysosomal membrane1.48e-011.00e+001.55422218
GO:0090263positive regulation of canonical Wnt signaling pathway1.48e-011.00e+002.6501151
GO:0000902cell morphogenesis1.48e-011.00e+002.6501151
GO:0030900forebrain development1.48e-011.00e+002.6501151
GO:0008202steroid metabolic process1.50e-011.00e+002.6221152
GO:0006184GTP catabolic process1.51e-011.00e+001.54126220
GO:0006952defense response1.53e-011.00e+002.5941153
GO:0030175filopodium1.53e-011.00e+002.5941253
GO:0003725double-stranded RNA binding1.56e-011.00e+002.5671254
GO:0009612response to mechanical stimulus1.56e-011.00e+002.5671154
GO:0000186activation of MAPKK activity1.56e-011.00e+002.5671154
GO:0050679positive regulation of epithelial cell proliferation1.56e-011.00e+002.5671254
GO:0097193intrinsic apoptotic signaling pathway1.58e-011.00e+002.5411255
GO:0002039p53 binding1.58e-011.00e+002.5411155
GO:0046330positive regulation of JNK cascade1.58e-011.00e+002.5411155
GO:0019221cytokine-mediated signaling pathway1.61e-011.00e+001.47725230
GO:0005793endoplasmic reticulum-Golgi intermediate compartment1.64e-011.00e+002.4891157
GO:0006879cellular iron ion homeostasis1.64e-011.00e+002.4891257
GO:0005643nuclear pore1.69e-011.00e+002.4391159
GO:0010976positive regulation of neuron projection development1.71e-011.00e+002.4151260
GO:0033138positive regulation of peptidyl-serine phosphorylation1.74e-011.00e+002.3911161
GO:0007596blood coagulation1.76e-011.00e+001.04935464
GO:0001078RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription1.77e-011.00e+002.3681162
GO:0000151ubiquitin ligase complex1.79e-011.00e+002.3451163
GO:0005901caveola1.79e-011.00e+002.3451163
GO:0043154negative regulation of cysteine-type endopeptidase activity involved in apoptotic process1.79e-011.00e+002.3451263
GO:0032869cellular response to insulin stimulus1.82e-011.00e+002.3221264
GO:0016491oxidoreductase activity1.84e-011.00e+002.3001165
GO:0043025neuronal cell body1.88e-011.00e+001.33325254
GO:0030141secretory granule1.90e-011.00e+002.2561267
GO:0004842ubiquitin-protein transferase activity1.90e-011.00e+001.32223256
GO:0006665sphingolipid metabolic process1.92e-011.00e+002.2351168
GO:0045893positive regulation of transcription, DNA-templated1.95e-011.00e+000.97938487
GO:0035264multicellular organism growth1.97e-011.00e+002.1931170
GO:0042393histone binding2.00e-011.00e+002.1721171
GO:0006281DNA repair2.00e-011.00e+001.27825264
GO:0001503ossification2.00e-011.00e+002.1721271
GO:0000165MAPK cascade2.02e-011.00e+002.1521272
GO:0000785chromatin2.05e-011.00e+002.1321273
GO:0055086nucleobase-containing small molecule metabolic process2.05e-011.00e+002.1321273
GO:0042826histone deacetylase binding2.07e-011.00e+002.1131174
GO:0000166nucleotide binding2.09e-011.00e+001.23522272
GO:0051897positive regulation of protein kinase B signaling2.10e-011.00e+002.0931175
GO:0060070canonical Wnt signaling pathway2.10e-011.00e+002.0931275
GO:0000977RNA polymerase II regulatory region sequence-specific DNA binding2.10e-011.00e+002.0931175
GO:0005975carbohydrate metabolic process2.11e-011.00e+001.22423274
GO:0044325ion channel binding2.15e-011.00e+002.0551377
GO:0055085transmembrane transport2.16e-011.00e+000.90133514
GO:0071013catalytic step 2 spliceosome2.20e-011.00e+002.0181179
GO:0031902late endosome membrane2.22e-011.00e+002.0001180
GO:0048471perinuclear region of cytoplasm2.24e-011.00e+000.87639523
GO:0045177apical part of cell2.27e-011.00e+001.9641182
GO:0001726ruffle2.27e-011.00e+001.9641182
GO:0019899enzyme binding2.27e-011.00e+001.15225288
GO:0004713protein tyrosine kinase activity2.27e-011.00e+001.9641182
GO:0030336negative regulation of cell migration2.29e-011.00e+001.9471283
GO:0007264small GTPase mediated signal transduction2.29e-011.00e+001.14227290
GO:0005929cilium2.32e-011.00e+001.9301284
GO:0005179hormone activity2.32e-011.00e+001.9301184
GO:0043234protein complex2.41e-011.00e+001.09329300
GO:0090090negative regulation of canonical Wnt signaling pathway2.41e-011.00e+001.8631388
GO:0042593glucose homeostasis2.44e-011.00e+001.8461189
GO:0042384cilium assembly2.46e-011.00e+001.8301290
GO:0005777peroxisome2.46e-011.00e+001.8301190
GO:0005524ATP binding2.46e-011.00e+000.5046191354
GO:0003690double-stranded DNA binding2.48e-011.00e+001.8141291
GO:0016337single organismal cell-cell adhesion2.51e-011.00e+001.7981292
GO:0042470melanosome2.51e-011.00e+001.7981292
GO:0005200structural constituent of cytoskeleton2.53e-011.00e+001.7831693
GO:0004674protein serine/threonine kinase activity2.55e-011.00e+001.03726312
GO:0005770late endosome2.55e-011.00e+001.7671194
GO:0035556intracellular signal transduction2.61e-011.00e+001.01425317
GO:0006355regulation of transcription, DNA-templated2.61e-011.00e+000.5355101104
GO:0005178integrin binding2.62e-011.00e+001.7221197
GO:0007411axon guidance2.72e-011.00e+000.96923327
GO:0005525GTP binding2.73e-011.00e+000.96426328
GO:0008283cell proliferation2.77e-011.00e+000.95124331
GO:0014069postsynaptic density2.83e-011.00e+001.59413106
GO:0006935chemotaxis2.88e-011.00e+001.56711108
GO:0030496midbody2.90e-011.00e+001.55414109
GO:0070374positive regulation of ERK1 and ERK2 cascade2.92e-011.00e+001.54111110
GO:0050900leukocyte migration2.94e-011.00e+001.52811111
GO:0020037heme binding2.94e-011.00e+001.52811111
GO:0015630microtubule cytoskeleton2.97e-011.00e+001.51514112
GO:0032496response to lipopolysaccharide3.18e-011.00e+001.39111122
GO:0051056regulation of small GTPase mediated signal transduction3.21e-011.00e+001.38013123
GO:0006511ubiquitin-dependent protein catabolic process3.29e-011.00e+001.33313127
GO:0005794Golgi apparatus3.32e-011.00e+000.56338650
GO:0030036actin cytoskeleton organization3.33e-011.00e+001.31113129
GO:0030027lamellipodium3.35e-011.00e+001.30013130
GO:0046983protein dimerization activity3.37e-011.00e+001.28913131
GO:0018108peptidyl-tyrosine phosphorylation3.42e-011.00e+001.26711133
GO:0007165signal transduction3.45e-011.00e+000.43047950
GO:0016055Wnt signaling pathway3.58e-011.00e+001.18213141
GO:0005911cell-cell junction3.60e-011.00e+001.17212142
GO:0000139Golgi membrane3.66e-011.00e+000.65027408
GO:0007166cell surface receptor signaling pathway3.74e-011.00e+001.10311149
GO:0044281small molecule metabolic process3.81e-011.00e+000.3055161295
GO:0006366transcription from RNA polymerase II promoter3.85e-011.00e+000.59123425
GO:0046777protein autophosphorylation3.92e-011.00e+001.01811158
GO:0000978RNA polymerase II core promoter proximal region sequence-specific DNA binding4.11e-011.00e+000.93014168
GO:0003700sequence-specific DNA binding transcription factor activity4.16e-011.00e+000.36039748
GO:0007420brain development4.18e-011.00e+000.89613172
GO:0016607nuclear speck4.23e-011.00e+000.87112175
GO:0031965nuclear membrane4.25e-011.00e+000.86312176
GO:0007049cell cycle4.27e-011.00e+000.85414177
GO:0006468protein phosphorylation4.31e-011.00e+000.45526467
GO:0031625ubiquitin protein ligase binding4.32e-011.00e+000.83014180
GO:0005764lysosome4.36e-011.00e+000.81412182
GO:0042802identical protein binding4.57e-011.00e+000.38224491
GO:0001525angiogenesis4.67e-011.00e+000.67813200
GO:0001701in utero embryonic development4.84e-011.00e+000.60812210
GO:0004871signal transducer activity4.94e-011.00e+000.56711216
GO:0016874ligase activity5.06e-011.00e+000.51512224
GO:0008380RNA splicing5.19e-011.00e+000.46415232
GO:0030425dendrite5.31e-011.00e+000.41513240
GO:0005102receptor binding5.71e-011.00e+000.25612268
GO:0006357regulation of transcription from RNA polymerase II promoter5.80e-011.00e+000.21912275
GO:0007283spermatogenesis5.82e-011.00e+000.21312276
GO:0042493response to drug5.97e-011.00e+000.15212288
GO:0016567protein ubiquitination6.11e-011.00e+000.09813299
GO:0005743mitochondrial inner membrane6.12e-011.00e+000.09311300
GO:0006955immune response6.18e-011.00e+000.06912305
GO:0003677DNA binding6.19e-011.00e+00-0.0784141351
GO:0005856cytoskeleton6.26e-011.00e+000.04116311
GO:0005575cellular_component6.39e-011.00e+00-0.00912322
GO:0030154cell differentiation6.42e-011.00e+00-0.02213325
GO:0007275multicellular organismal development6.63e-011.00e+00-0.10412344
GO:0015031protein transport6.77e-011.00e+00-0.15814357
GO:0005886plasma membrane6.81e-011.00e+00-0.1478242834
GO:0046872metal ion binding6.83e-011.00e+00-0.1954141465
GO:0008285negative regulation of cell proliferation6.87e-011.00e+00-0.19813367
GO:0007155cell adhesion7.04e-011.00e+00-0.26313384
GO:0045892negative regulation of transcription, DNA-templated7.39e-011.00e+00-0.40612424
GO:0008150biological_process7.67e-011.00e+00-0.52013459
GO:0055114oxidation-reduction process7.83e-011.00e+00-0.58812481
GO:0008270zinc ion binding8.55e-011.00e+00-0.737271067
GO:0005783endoplasmic reticulum8.57e-011.00e+00-0.93116610
GO:0042803protein homodimerization activity8.60e-011.00e+00-0.94714617
GO:0005615extracellular space9.62e-011.00e+00-1.658131010