reg-snw-1432

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
tai-screen-luciferase	4.670	5.00e-24	6.11e-04	9.80e-04

tai-screen-luciferase-reg-snw-1432 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	tai-screen-luciferase gene score	Best subnetwork score	Degree	Transcription factor	List-Gonzales GI	Tai-Hits
ZNF672	79894	1	-2.681	4.670	98	TF	-	-
COPA	1314	25	-9.395	5.672	170	TF	Yes	Yes
HSF1	3297	8	-4.179	5.027	138	TF	-	Yes
MRPS12	6183	13	-5.421	5.516	307	TF	Yes	-
YBX1	4904	6	-3.033	5.516	120	TF	-	-
[ MAPK14 ]	1432	1	2.079	4.670	32	-	-	-
SERBP1	26135	10	-4.612	5.516	43	-	-	Yes
CDC5L	988	15	-3.419	5.672	155	TF	-	-
CKAP5	9793	20	-7.214	5.672	89	TF	Yes	Yes

Interactions (12)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
HSF1	3297	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
MAPK14	1432	YBX1	4904	pd	<	reg.ITFP.txt: no annot
MAPK14	1432	HSF1	3297	pd	<	reg.ITFP.txt: no annot
COPA	1314	MAPK14	1432	pd	>	reg.ITFP.txt: no annot
CDC5L	988	COPA	1314	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	YBX1	4904	pd	<>	reg.ITFP.txt: no annot
MAPK14	1432	ZNF672	79894	pd	<	reg.ITFP.txt: no annot
YBX1	4904	MRPS12	6183	pd	<>	reg.ITFP.txt: no annot
CDC5L	988	MAPK14	1432	pd	>	reg.ITFP.txt: no annot
CDC5L	988	CKAP5	9793	pd	<>	reg.ITFP.txt: no annot
YBX1	4904	SERBP1	26135	pd	>	reg.ITFP.txt: no annot
HSF1	3297	ZNF672	79894	pd	<>	reg.ITFP.txt: no annot

Related GO terms (156)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0038066	p38MAPK cascade	9.22e-04	1.00e+00	10.083	1	1	1
GO:0014835	myoblast differentiation involved in skeletal muscle regeneration	9.22e-04	1.00e+00	10.083	1	1	1
GO:0071987	WD40-repeat domain binding	9.22e-04	1.00e+00	10.083	1	1	1
GO:0000922	spindle pole	1.67e-03	1.00e+00	4.996	2	3	68
GO:0090231	regulation of spindle checkpoint	1.84e-03	1.00e+00	9.083	1	1	2
GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity	1.84e-03	1.00e+00	9.083	1	1	2
GO:0072422	signal transduction involved in DNA damage checkpoint	1.84e-03	1.00e+00	9.083	1	1	2
GO:0051154	negative regulation of striated muscle cell differentiation	2.76e-03	1.00e+00	8.499	1	1	3
GO:0090400	stress-induced premature senescence	2.76e-03	1.00e+00	8.499	1	1	3
GO:0007143	female meiotic division	2.76e-03	1.00e+00	8.499	1	1	3
GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	2.76e-03	1.00e+00	8.499	1	1	3
GO:0050658	RNA transport	3.68e-03	1.00e+00	8.083	1	1	4
GO:0030157	pancreatic juice secretion	3.68e-03	1.00e+00	8.083	1	1	4
GO:0044822	poly(A) RNA binding	4.01e-03	1.00e+00	2.441	4	25	799
GO:0000974	Prp19 complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	4.60e-03	1.00e+00	7.762	1	1	5
GO:0051525	NFAT protein binding	4.60e-03	1.00e+00	7.762	1	1	5
GO:1901741	positive regulation of myoblast fusion	4.60e-03	1.00e+00	7.762	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0000930	gamma-tubulin complex	4.60e-03	1.00e+00	7.762	1	1	5
GO:0060136	embryonic process involved in female pregnancy	5.52e-03	1.00e+00	7.499	1	1	6
GO:0070937	CRD-mediated mRNA stability complex	5.52e-03	1.00e+00	7.499	1	1	6
GO:0010831	positive regulation of myotube differentiation	5.52e-03	1.00e+00	7.499	1	1	6
GO:0000398	mRNA splicing, via spliceosome	5.78e-03	1.00e+00	4.083	2	2	128
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	6.44e-03	1.00e+00	7.276	1	1	7
GO:0004707	MAP kinase activity	6.44e-03	1.00e+00	7.276	1	1	7
GO:0030126	COPI vesicle coat	6.44e-03	1.00e+00	7.276	1	1	7
GO:0005662	DNA replication factor A complex	7.35e-03	1.00e+00	7.083	1	1	8
GO:0004708	MAP kinase kinase activity	7.35e-03	1.00e+00	7.083	1	1	8
GO:0019395	fatty acid oxidation	7.35e-03	1.00e+00	7.083	1	1	8
GO:0032495	response to muramyl dipeptide	7.35e-03	1.00e+00	7.083	1	1	8
GO:0045663	positive regulation of myoblast differentiation	8.27e-03	1.00e+00	6.914	1	1	9
GO:0007051	spindle organization	9.18e-03	1.00e+00	6.762	1	1	10
GO:0043488	regulation of mRNA stability	9.18e-03	1.00e+00	6.762	1	1	10
GO:0070935	3'-UTR-mediated mRNA stabilization	1.01e-02	1.00e+00	6.624	1	1	11
GO:0042770	signal transduction in response to DNA damage	1.01e-02	1.00e+00	6.624	1	1	11
GO:0045120	pronucleus	1.01e-02	1.00e+00	6.624	1	1	11
GO:0042307	positive regulation of protein import into nucleus	1.10e-02	1.00e+00	6.499	1	2	12
GO:0051297	centrosome organization	1.10e-02	1.00e+00	6.499	1	1	12
GO:0048205	COPI coating of Golgi vesicle	1.10e-02	1.00e+00	6.499	1	1	12
GO:0015935	small ribosomal subunit	1.10e-02	1.00e+00	6.499	1	4	12
GO:0051146	striated muscle cell differentiation	1.10e-02	1.00e+00	6.499	1	2	12
GO:0006351	transcription, DNA-templated	1.17e-02	1.00e+00	2.012	4	15	1076
GO:0035371	microtubule plus-end	1.19e-02	1.00e+00	6.383	1	1	13
GO:0001502	cartilage condensation	1.19e-02	1.00e+00	6.383	1	1	13
GO:0043536	positive regulation of blood vessel endothelial cell migration	1.28e-02	1.00e+00	6.276	1	1	14
GO:0005737	cytoplasm	1.47e-02	1.00e+00	1.306	6	39	2633
GO:0048010	vascular endothelial growth factor receptor signaling pathway	1.47e-02	1.00e+00	6.083	1	1	16
GO:0043234	protein complex	1.50e-02	1.00e+00	3.369	2	8	210
GO:0045648	positive regulation of erythrocyte differentiation	1.56e-02	1.00e+00	5.996	1	1	17
GO:0005689	U12-type spliceosomal complex	1.56e-02	1.00e+00	5.996	1	2	17
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	1.56e-02	1.00e+00	5.996	1	1	17
GO:0051090	regulation of sequence-specific DNA binding transcription factor activity	1.65e-02	1.00e+00	5.914	1	1	18
GO:0030316	osteoclast differentiation	1.65e-02	1.00e+00	5.914	1	1	18
GO:0035924	cellular response to vascular endothelial growth factor stimulus	1.65e-02	1.00e+00	5.914	1	1	18
GO:0016020	membrane	1.75e-02	1.00e+00	1.846	4	25	1207
GO:0001892	embryonic placenta development	1.83e-02	1.00e+00	5.762	1	1	20
GO:0032720	negative regulation of tumor necrosis factor production	1.83e-02	1.00e+00	5.762	1	1	20
GO:0005761	mitochondrial ribosome	1.83e-02	1.00e+00	5.762	1	1	20
GO:0000077	DNA damage checkpoint	1.92e-02	1.00e+00	5.691	1	1	21
GO:2000379	positive regulation of reactive oxygen species metabolic process	1.92e-02	1.00e+00	5.691	1	1	21
GO:0051149	positive regulation of muscle cell differentiation	2.01e-02	1.00e+00	5.624	1	2	22
GO:0051781	positive regulation of cell division	2.01e-02	1.00e+00	5.624	1	1	22
GO:0040018	positive regulation of multicellular organism growth	2.01e-02	1.00e+00	5.624	1	1	22
GO:0002062	chondrocyte differentiation	2.01e-02	1.00e+00	5.624	1	1	22
GO:0034605	cellular response to heat	2.01e-02	1.00e+00	5.624	1	1	22
GO:0003682	chromatin binding	2.12e-02	1.00e+00	3.106	2	3	252
GO:0071479	cellular response to ionizing radiation	2.19e-02	1.00e+00	5.499	1	1	24
GO:0003730	mRNA 3'-UTR binding	2.28e-02	1.00e+00	5.440	1	1	25
GO:0006355	regulation of transcription, DNA-templated	2.35e-02	1.00e+00	2.187	3	9	715
GO:0010494	cytoplasmic stress granule	2.37e-02	1.00e+00	5.383	1	2	26
GO:0031663	lipopolysaccharide-mediated signaling pathway	2.46e-02	1.00e+00	5.329	1	1	27
GO:0042692	muscle cell differentiation	2.55e-02	1.00e+00	5.276	1	2	28
GO:0007519	skeletal muscle tissue development	3.00e-02	1.00e+00	5.039	1	1	33
GO:0000902	cell morphogenesis	3.18e-02	1.00e+00	4.954	1	1	35
GO:0006952	defense response	3.36e-02	1.00e+00	4.874	1	1	37
GO:0005515	protein binding	3.44e-02	1.00e+00	0.881	7	50	4124
GO:0051403	stress-activated MAPK cascade	3.81e-02	1.00e+00	4.691	1	2	42
GO:0005634	nucleus	4.18e-02	1.00e+00	1.004	6	40	3246
GO:0001078	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription	4.52e-02	1.00e+00	4.440	1	1	50
GO:0034146	toll-like receptor 5 signaling pathway	4.52e-02	1.00e+00	4.440	1	2	50
GO:0034166	toll-like receptor 10 signaling pathway	4.52e-02	1.00e+00	4.440	1	2	50
GO:0018105	peptidyl-serine phosphorylation	4.61e-02	1.00e+00	4.411	1	2	51
GO:0003677	DNA binding	4.89e-02	1.00e+00	1.781	3	12	947
GO:0070062	extracellular vesicular exosome	4.92e-02	1.00e+00	1.403	4	28	1641
GO:0038123	toll-like receptor TLR1:TLR2 signaling pathway	4.96e-02	1.00e+00	4.302	1	2	55
GO:0034162	toll-like receptor 9 signaling pathway	4.96e-02	1.00e+00	4.302	1	2	55
GO:0038124	toll-like receptor TLR6:TLR2 signaling pathway	4.96e-02	1.00e+00	4.302	1	2	55
GO:0034134	toll-like receptor 2 signaling pathway	5.05e-02	1.00e+00	4.276	1	2	56
GO:0035666	TRIF-dependent toll-like receptor signaling pathway	5.13e-02	1.00e+00	4.251	1	2	57
GO:0003697	single-stranded DNA binding	5.13e-02	1.00e+00	4.251	1	3	57
GO:0006935	chemotaxis	5.22e-02	1.00e+00	4.225	1	1	58
GO:0002756	MyD88-independent toll-like receptor signaling pathway	5.22e-02	1.00e+00	4.225	1	2	58
GO:0034138	toll-like receptor 3 signaling pathway	5.31e-02	1.00e+00	4.201	1	2	59
GO:0090090	negative regulation of canonical Wnt signaling pathway	5.31e-02	1.00e+00	4.201	1	3	59
GO:0007265	Ras protein signal transduction	5.31e-02	1.00e+00	4.201	1	2	59
GO:0005179	hormone activity	5.40e-02	1.00e+00	4.177	1	1	60
GO:0071013	catalytic step 2 spliceosome	5.49e-02	1.00e+00	4.153	1	1	61
GO:0002755	MyD88-dependent toll-like receptor signaling pathway	5.49e-02	1.00e+00	4.153	1	2	61
GO:0000187	activation of MAPK activity	5.66e-02	1.00e+00	4.106	1	2	63
GO:0071222	cellular response to lipopolysaccharide	5.75e-02	1.00e+00	4.083	1	1	64
GO:0006928	cellular component movement	6.27e-02	1.00e+00	3.954	1	3	70
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	6.30e-02	1.00e+00	2.251	2	6	456
GO:0034142	toll-like receptor 4 signaling pathway	6.53e-02	1.00e+00	3.894	1	2	73
GO:0015630	microtubule cytoskeleton	6.71e-02	1.00e+00	3.855	1	2	75
GO:0006006	glucose metabolic process	7.14e-02	1.00e+00	3.762	1	2	80
GO:0030529	ribonucleoprotein complex	7.31e-02	1.00e+00	3.726	1	3	82
GO:0003690	double-stranded DNA binding	7.40e-02	1.00e+00	3.708	1	1	83
GO:0002224	toll-like receptor signaling pathway	7.40e-02	1.00e+00	3.708	1	2	83
GO:0007166	cell surface receptor signaling pathway	7.91e-02	1.00e+00	3.608	1	1	89
GO:0061024	membrane organization	7.91e-02	1.00e+00	3.608	1	3	89
GO:0006886	intracellular protein transport	7.91e-02	1.00e+00	3.608	1	1	89
GO:0032496	response to lipopolysaccharide	8.26e-02	1.00e+00	3.544	1	1	93
GO:0010467	gene expression	8.35e-02	1.00e+00	2.020	2	17	535
GO:0000086	G2/M transition of mitotic cell cycle	8.60e-02	1.00e+00	3.484	1	3	97
GO:0005198	structural molecule activity	8.94e-02	1.00e+00	3.425	1	1	101
GO:0003735	structural constituent of ribosome	9.61e-02	1.00e+00	3.315	1	8	109
GO:0003700	sequence-specific DNA binding transcription factor activity	9.66e-02	1.00e+00	1.899	2	9	582
GO:0042981	regulation of apoptotic process	9.87e-02	1.00e+00	3.276	1	4	112
GO:0016607	nuclear speck	1.07e-01	1.00e+00	3.153	1	2	122
GO:0031965	nuclear membrane	1.14e-01	1.00e+00	3.061	1	2	130
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	1.15e-01	1.00e+00	1.753	2	8	644
GO:0030168	platelet activation	1.23e-01	1.00e+00	2.944	1	3	141
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	1.24e-01	1.00e+00	2.934	1	4	142
GO:0001525	angiogenesis	1.27e-01	1.00e+00	2.894	1	2	146
GO:0001701	in utero embryonic development	1.33e-01	1.00e+00	2.817	1	2	154
GO:0008380	RNA splicing	1.42e-01	1.00e+00	2.717	1	4	165
GO:0007067	mitotic nuclear division	1.42e-01	1.00e+00	2.717	1	5	165
GO:0007283	spermatogenesis	1.45e-01	1.00e+00	2.691	1	2	168
GO:0016071	mRNA metabolic process	1.46e-01	1.00e+00	2.674	1	11	170
GO:0006412	translation	1.53e-01	1.00e+00	2.608	1	13	178
GO:0016070	RNA metabolic process	1.61e-01	1.00e+00	2.529	1	11	188
GO:0004674	protein serine/threonine kinase activity	1.68e-01	1.00e+00	2.461	1	3	197
GO:0048011	neurotrophin TRK receptor signaling pathway	1.69e-01	1.00e+00	2.447	1	2	199
GO:0035556	intracellular signal transduction	1.69e-01	1.00e+00	2.447	1	3	199
GO:0006357	regulation of transcription from RNA polymerase II promoter	1.72e-01	1.00e+00	2.418	1	1	203
GO:0005813	centrosome	1.83e-01	1.00e+00	2.322	1	6	217
GO:0043231	intracellular membrane-bounded organelle	1.84e-01	1.00e+00	2.315	1	1	218
GO:0005654	nucleoplasm	1.90e-01	1.00e+00	1.309	2	16	876
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	6	247
GO:0005829	cytosol	2.18e-01	1.00e+00	0.865	3	33	1787
GO:0008285	negative regulation of cell proliferation	2.28e-01	1.00e+00	1.970	1	3	277
GO:0006468	protein phosphorylation	2.46e-01	1.00e+00	1.850	1	3	301
GO:0000278	mitotic cell cycle	2.55e-01	1.00e+00	1.789	1	9	314
GO:0007596	blood coagulation	2.72e-01	1.00e+00	1.678	1	4	339
GO:0006366	transcription from RNA polymerase II promoter	2.74e-01	1.00e+00	1.670	1	2	341
GO:0048471	perinuclear region of cytoplasm	2.76e-01	1.00e+00	1.657	1	7	344
GO:0005730	nucleolus	3.11e-01	1.00e+00	0.834	2	21	1217
GO:0006915	apoptotic process	3.21e-01	1.00e+00	1.400	1	4	411
GO:0045087	innate immune response	3.47e-01	1.00e+00	1.263	1	6	452
GO:0007165	signal transduction	4.45e-01	1.00e+00	0.812	1	5	618
GO:0005615	extracellular space	4.63e-01	1.00e+00	0.737	1	2	651
GO:0005739	mitochondrion	4.67e-01	1.00e+00	0.719	1	4	659
GO:0005524	ATP binding	5.78e-01	1.00e+00	0.283	1	10	892
GO:0046872	metal ion binding	5.96e-01	1.00e+00	0.216	1	10	934
GO:0005886	plasma membrane	8.37e-01	1.00e+00	-0.717	1	13	1784

Tai-Luciferase

reg-snw-1432

Statistics

Genes (9)

Interactions (12)

Related GO terms (156)