meta-int-snw-6189

Interacting subnets

Subnetwork Dataset Score p-value 1 p-value 2 p-value 3 Size Highlighted genes
reg-snw-55854 tai-screen-luciferase 4.880 1.80e-26 2.35e-04 4.05e-04 5 3
int-snw-6189 tai-screen-luciferase 7.011 2.96e-170 3.75e-09 3.42e-04 18 16
reg-snw-1964 tai-screen-luciferase 4.532 1.75e-22 1.10e-03 1.69e-03 7 6
reg-snw-1500 tai-screen-luciferase 4.226 2.77e-19 3.65e-03 4.98e-03 9 7
reg-snw-84343 tai-screen-luciferase 4.236 2.24e-19 3.52e-03 4.83e-03 10 5
tai-screen-luciferase-meta-int-snw-6189 subnetwork

Genes (37)

Gene Symbol Entrez Gene ID Frequency tai-screen-luciferase gene score Best subnetwork score Degree List-Gonzales GI Tai-Hits
RPS8 6202 33-5.5457.555234--
CHMP2A 27243 33-9.0377.55541YesYes
RPS15 6209 30-5.0407.011116Yes-
RPS2 6187 16-3.2414.22613Yes-
COPA 1314 48-9.3955.672340YesYes
CTSF 8722 8-3.9784.2361-Yes
EIF1AX 1964 14-3.0054.53243Yes-
COPB2 9276 48-13.1689.06341YesYes
CKAP5 9793 46-7.2145.672130YesYes
EIF2S2 8894 31-4.3205.672103Yes-
ZC3H15 55854 143.2694.88011--
RPS16 6217 38-5.4444.880205--
UTP18 51096 8-1.7094.236106--
RPS11 6205 44-6.5887.555175Yes-
RPS6 6194 44-5.6038.046217Yes-
TLK2 11011 21-4.0115.67214--
RAN 5901 38-3.8094.325258YesYes
RPS13 6207 43-6.5897.555174Yes-
CDC5L 988 34-3.4195.672155--
HPS3 84343 8-1.5164.23641--
RPS24 6229 46-7.0348.389217Yes-
RPS9 6203 45-7.1277.555140Yes-
RPS3A 6189 19-4.6477.189166Yes-
RPS4X 6191 44-6.7477.555263Yes-
PES1 23481 162.9174.22691--
COPZ1 22818 48-8.3019.06313YesYes
YEATS4 8089 14-4.4444.53218YesYes
BRCA2 675 8-1.9914.236111--
RPS15A 6210 36-5.4137.555177Yes-
WDR46 9277 31-4.2904.226101YesYes
EIF2S3 1968 14-3.1444.53213Yes-
RPS27A 6233 45-5.6318.389344Yes-
RPS14 6208 23-4.8037.011204Yes-
EIF3M 10480 184.4514.88055Yes-
CTNND1 1500 16-2.6514.22653Yes-
RPS26 6231 43-7.4788.04660Yes-
ARCN1 372 48-8.2329.063118YesYes

Interactions (132)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
RPS4X 6191 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, Tarassov_PCA, YeastMedium, INTEROLOG
EIF2S2 8894 PES1 23481 pp -- int.I2D: YeastLow
RPS11 6205 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS11 6205 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS2 6187 RPS14 6208 pp -- int.I2D: INTEROLOG, YeastMedium, BioGrid_Yeast
RPS2 6187 RPS4X 6191 pp -- int.I2D: YeastHigh, YeastMedium, INTEROLOG
RPS11 6205 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
WDR46 9277 UTP18 51096 pp -- int.I2D: YeastLow
CDC5L 988 HPS3 84343 pd > reg.ITFP.txt: no annot
RPS14 6208 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS26 6231 pp -- int.I2D: YeastLow
ARCN1 372 RAN 5901 pp -- int.I2D: YeastLow
RPS15 6209 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
RPS8 6202 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 RPS11 6205 pp -- int.I2D: YeastMedium
RPS4X 6191 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS9 6203 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 EIF2S3 1968 pd > reg.ITFP.txt: no annot
RPS8 6202 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS9 6203 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS11 6205 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
UTP18 51096 HPS3 84343 pd > reg.ITFP.txt: no annot
RAN 5901 RPS11 6205 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, MINT_Worm, NON_CORE
RPS13 6207 WDR46 9277 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 RPS15A 6210 pp -- int.I2D: YeastMedium
RPS4X 6191 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS2 6187 RPS3A 6189 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 RPS15 6209 pp -- int.I2D: YeastMedium
RPS3A 6189 RPS9 6203 pp -- int.I2D: IntAct
RPS9 6203 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS14 6208 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS2 6187 PES1 23481 pp -- int.I2D: IntAct_Yeast
EIF1AX 1964 RPS2 6187 pp -- int.I2D: YeastMedium
RPS2 6187 RPS15 6209 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS2 6187 RPS9 6203 pp -- int.I2D: BIND_Yeast
RPS15A 6210 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS11 6205 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS2 6187 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS8 6202 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
RPS16 6217 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CTNND1 1500 PES1 23481 pd <> reg.ITFP.txt: no annot
RPS4X 6191 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 YEATS4 8089 pd > reg.ITFP.txt: no annot
RAN 5901 RPS15 6209 pp -- int.I2D: YeastLow
EIF1AX 1964 RPS9 6203 pp -- int.I2D: YeastMedium
RPS4X 6191 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast, YeastMedium, INTEROLOG
RPS8 6202 RPS9 6203 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS13 6207 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS6 6194 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 RPS27A 6233 pp -- int.I2D: YeastLow
RPS3A 6189 RPS4X 6191 pp -- int.I2D: BioGrid_Yeast
RAN 5901 RPS2 6187 pp -- int.I2D: IntAct_Worm, BioGrid_Worm, BIND_Worm, CORE_2, MINT_Worm
RPS8 6202 CHMP2A 27243 pp -- int.I2D: BioGrid_Yeast
RPS8 6202 PES1 23481 pp -- int.I2D: IntAct_Yeast
CDC5L 988 CKAP5 9793 pd <> reg.ITFP.txt: no annot
RPS16 6217 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS2 6187 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
RAN 5901 WDR46 9277 pp -- int.I2D: YeastLow
RPS15 6209 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS3A 6189 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
EIF2S3 1968 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
BRCA2 675 CTSF 8722 pd > reg.ITFP.txt: no annot
RPS14 6208 UTP18 51096 pd < reg.ITFP.txt: no annot
WDR46 9277 PES1 23481 pd <> reg.ITFP.txt: no annot
RPS3A 6189 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
COPA 1314 COPZ1 22818 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast, Krogan_Core, MINT_Yeast, YeastMedium
RPS6 6194 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
COPA 1314 COPB2 9276 pp -- int.I2D: BioGrid, HPRD, BCI;
int.HPRD: in vivo
RPS15 6209 RPS16 6217 pp -- int.I2D: BioGrid_Yeast, INTEROLOG, YeastMedium
RPS2 6187 RPS11 6205 pp -- int.I2D: YeastMedium, INTEROLOG
RPS3A 6189 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS6 6194 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS4X 6191 RPS8 6202 pp -- int.I2D: BioGrid_Yeast
RPS4X 6191 RPS13 6207 pp -- int.I2D: BioGrid_Yeast
EIF1AX 1964 EIF2S2 8894 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS24 6229 pp -- int.I2D: BioGrid_Yeast
CDC5L 988 TLK2 11011 pd > reg.ITFP.txt: no annot
EIF1AX 1964 RPS14 6208 pp -- int.I2D: YeastMedium
RPS13 6207 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
RPS13 6207 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS2 6187 RPS15A 6210 pp -- int.I2D: INTEROLOG, YeastMedium, BIND_Yeast
RPS4X 6191 RPS15 6209 pp -- int.I2D: INTEROLOG, YeastMedium
CTNND1 1500 RPS2 6187 pd > reg.ITFP.txt: no annot
EIF1AX 1964 RPS16 6217 pp -- int.I2D: YeastMedium
RPS11 6205 RPS14 6208 pp -- int.I2D: BioGrid_Yeast
RPS2 6187 RPS16 6217 pp -- int.I2D: INTEROLOG, YeastMedium, BioGrid_Yeast
CDC5L 988 COPA 1314 pd <> reg.ITFP.txt: no annot
CDC5L 988 EIF2S2 8894 pd > reg.ITFP.txt: no annot
RPS13 6207 PES1 23481 pp -- int.I2D: IntAct_Yeast
BRCA2 675 HPS3 84343 pd > reg.ITFP.txt: no annot
RPS9 6203 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS15 6209 RPS15A 6210 pp -- int.I2D: YeastMedium, INTEROLOG
RPS6 6194 RPS16 6217 pp -- int.I2D: BioGrid_Yeast
ARCN1 372 RPS3A 6189 pp -- int.I2D: IntAct_Yeast
ARCN1 372 COPA 1314 pp -- int.I2D: BCI, BioGrid_Yeast, IntAct_Yeast, MINT_Yeast, YeastHigh, HPRD, Krogan_Core;
int.HPRD: in vivo
EIF2S3 1968 RPS11 6205 pp -- int.I2D: BioGrid_Yeast, IntAct_Yeast
EIF1AX 1964 EIF3M 10480 pd <> reg.ITFP.txt: no annot
RPS6 6194 RPS8 6202 pp -- int.I2D: BioGrid_Yeast, YeastLow
RPS4X 6191 RPS6 6194 pp -- int.I2D: BioGrid_Yeast
EIF3M 10480 ZC3H15 55854 pd > reg.ITFP.txt: no annot
CDC5L 988 RPS16 6217 pp -- int.I2D: BioGrid
COPA 1314 RPS27A 6233 pp -- int.I2D: YeastLow
RPS8 6202 RPS15A 6210 pp -- int.I2D: BioGrid_Yeast
COPA 1314 HPS3 84343 pd > reg.ITFP.txt: no annot
RPS16 6217 RPS26 6231 pp -- int.I2D: BioGrid_Yeast
RPS15A 6210 RPS27A 6233 pp -- int.I2D: YeastLow
ARCN1 372 COPB2 9276 pp -- int.I2D: HPRD, BCI;
int.HPRD: in vivo
RAN 5901 PES1 23481 pd < reg.ITFP.txt: no annot
EIF2S3 1968 EIF2S2 8894 pp -- int.Intact: MI:0407(direct interaction);
int.I2D: BioGrid_Yeast, IntAct, IntAct_Yeast, MINT_Yeast, YeastHigh, Yu_GoldStd
RPS6 6194 PES1 23481 pp -- int.I2D: IntAct_Yeast
RPS13 6207 RPS15 6209 pp -- int.I2D: BioGrid_Yeast
RPS24 6229 RPS27A 6233 pp -- int.I2D: YeastMedium
RPS27A 6233 EIF3M 10480 pd < reg.ITFP.txt: no annot
RPS8 6202 RPS11 6205 pp -- int.I2D: BioGrid_Yeast
RPS3A 6189 RPS6 6194 pp -- int.I2D: BioGrid_Yeast, YeastLow

Related GO terms (316)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0022627cytosolic small ribosomal subunit1.94e-313.16e-277.406152139
GO:0006413translational initiation6.18e-311.01e-265.9991927131
GO:0019058viral life cycle1.07e-271.75e-236.0271725115
GO:0019083viral transcription5.94e-269.70e-226.352152281
GO:0006415translational termination1.91e-253.11e-216.249152287
GO:0006414translational elongation5.61e-259.16e-216.153152293
GO:0006614SRP-dependent cotranslational protein targeting to membrane3.38e-245.52e-205.9911522104
GO:0006412translation5.09e-248.30e-205.0781829235
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay1.46e-232.38e-195.8591522114
GO:0003735structural constituent of ribosome4.14e-226.75e-185.5521524141
GO:0044822poly(A) RNA binding5.78e-209.44e-163.29624421078
GO:0016071mRNA metabolic process4.83e-197.88e-154.8911529223
GO:0016070RNA metabolic process2.27e-183.71e-144.7441529247
GO:0044267cellular protein metabolic process3.61e-185.89e-144.0041829495
GO:0010467gene expression3.01e-174.92e-133.6471936669
GO:0016032viral process4.59e-167.49e-123.7961737540
GO:0005829cytosol1.59e-132.60e-092.16226742562
GO:0015935small ribosomal subunit1.08e-121.76e-087.2826917
GO:0016020membrane8.69e-121.42e-072.40721481746
GO:0005925focal adhesion6.41e-091.05e-043.5761023370
GO:0042274ribosomal small subunit biogenesis1.09e-081.78e-047.2004612
GO:0048205COPI coating of Golgi vesicle1.57e-082.57e-047.0854613
GO:0030126COPI vesicle coat1.57e-082.57e-047.0854613
GO:0006364rRNA processing7.10e-081.16e-034.7856896
GO:0006890retrograde vesicle-mediated transport, Golgi to ER2.73e-074.46e-036.1414625
GO:0061024membrane organization8.55e-071.40e-024.180611146
GO:0070062extracellular vesicular exosome2.09e-063.41e-021.65818512516
GO:0003743translation initiation factor activity4.40e-067.18e-025.1704549
GO:0030529ribonucleoprotein complex5.55e-069.06e-024.27458114
GO:0005730nucleolus9.05e-061.48e-011.87514361684
GO:0005840ribosome9.30e-061.52e-014.90241059
GO:0000056ribosomal small subunit export from nucleus1.50e-052.45e-018.200223
GO:0008135translation factor activity, nucleic acid binding2.10e-053.43e-015.7853424
GO:0019843rRNA binding3.02e-054.93e-015.6153427
GO:0000462maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.98e-058.13e-017.463235
GO:0033119negative regulation of RNA splicing4.98e-058.13e-017.463225
GO:0045182translation regulator activity7.46e-051.00e+007.200226
GO:0000028ribosomal small subunit assembly1.04e-041.00e+006.978237
GO:0031369translation initiation factor binding5.15e-041.00e+005.8782215
GO:0003729mRNA binding5.98e-041.00e+004.1803373
GO:0006886intracellular protein transport6.13e-041.00e+003.35046173
GO:0075733intracellular transport of virus6.66e-041.00e+005.6982317
GO:0006891intra-Golgi vesicle-mediated transport6.66e-041.00e+005.6982317
GO:0043473pigmentation9.26e-041.00e+005.4632220
GO:0036464cytoplasmic ribonucleoprotein granule1.12e-031.00e+005.3262522
GO:0003723RNA binding1.16e-031.00e+002.635510355
GO:0005844polysome1.45e-031.00e+005.1412225
GO:0007067mitotic nuclear division1.79e-031.00e+002.93347231
GO:0043967histone H4 acetylation1.82e-031.00e+004.9782228
GO:0005515protein binding2.04e-031.00e+000.72823876127
GO:0022605oogenesis stage2.27e-031.00e+008.785111
GO:0033593BRCA2-MAGE-D1 complex2.27e-031.00e+008.785111
GO:0002183cytoplasmic translational initiation2.27e-031.00e+008.785111
GO:0021691cerebellar Purkinje cell layer maturation2.27e-031.00e+008.785111
GO:0071987WD40-repeat domain binding4.53e-031.00e+007.785112
GO:0002176male germ cell proliferation4.53e-031.00e+007.785112
GO:0000466maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)4.53e-031.00e+007.785112
GO:0072422signal transduction involved in DNA damage checkpoint4.53e-031.00e+007.785112
GO:0001672regulation of chromatin assembly or disassembly4.53e-031.00e+007.785112
GO:0070545PeBoW complex6.79e-031.00e+007.200113
GO:0000463maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)6.79e-031.00e+007.200113
GO:0031084BLOC-2 complex6.79e-031.00e+007.200113
GO:0030951establishment or maintenance of microtubule cytoskeleton polarity6.79e-031.00e+007.200113
GO:0005850eukaryotic translation initiation factor 2 complex6.79e-031.00e+007.200113
GO:0010484H3 histone acetyltransferase activity6.79e-031.00e+007.200113
GO:0030687preribosome, large subunit precursor6.79e-031.00e+007.200113
GO:0016197endosomal transport7.63e-031.00e+003.9272358
GO:0006417regulation of translation8.95e-031.00e+003.8082463
GO:0030490maturation of SSU-rRNA9.04e-031.00e+006.785124
GO:0007000nucleolus organization9.04e-031.00e+006.785124
GO:0048478replication fork protection9.04e-031.00e+006.785114
GO:0000055ribosomal large subunit export from nucleus9.04e-031.00e+006.785114
GO:0005654nucleoplasm1.05e-021.00e+001.4967261095
GO:1902188positive regulation of viral release from host cell1.13e-021.00e+006.463115
GO:0033600negative regulation of mammary gland epithelial cell proliferation1.13e-021.00e+006.463115
GO:0010485H4 histone acetyltransferase activity1.35e-021.00e+006.200116
GO:0002181cytoplasmic translation1.35e-021.00e+006.200126
GO:0002309T cell proliferation involved in immune response1.35e-021.00e+006.200116
GO:0000974Prp19 complex1.35e-021.00e+006.200116
GO:0051347positive regulation of transferase activity1.35e-021.00e+006.200116
GO:0006924activation-induced cell death of T cells1.35e-021.00e+006.200126
GO:0050792regulation of viral process1.35e-021.00e+006.200116
GO:0050658RNA transport1.58e-021.00e+005.978117
GO:0048027mRNA 5'-UTR binding1.58e-021.00e+005.978117
GO:0034101erythrocyte homeostasis1.58e-021.00e+005.978117
GO:0030157pancreatic juice secretion1.58e-021.00e+005.978117
GO:0071541eukaryotic translation initiation factor 3 complex, eIF3m1.58e-021.00e+005.978117
GO:0000930gamma-tubulin complex1.58e-021.00e+005.978117
GO:0039702viral budding via host ESCRT complex1.80e-021.00e+005.785118
GO:0001649osteoblast differentiation1.96e-021.00e+003.2152395
GO:0005915zonula adherens2.02e-021.00e+005.615119
GO:0005737cytoplasm2.16e-021.00e+000.73515653976
GO:0006996organelle organization2.24e-021.00e+005.4631110
GO:0010225response to UV-C2.24e-021.00e+005.4631110
GO:0007051spindle organization2.69e-021.00e+005.2001112
GO:0043968histone H2A acetylation2.69e-021.00e+005.2001112
GO:1903543positive regulation of exosomal secretion2.69e-021.00e+005.2001112
GO:0019082viral protein processing2.69e-021.00e+005.2001212
GO:0042273ribosomal large subunit biogenesis2.91e-021.00e+005.0851113
GO:0031929TOR signaling2.91e-021.00e+005.0851113
GO:0032479regulation of type I interferon production2.91e-021.00e+005.0851213
GO:0005662DNA replication factor A complex2.91e-021.00e+005.0851113
GO:0001833inner cell mass cell proliferation2.91e-021.00e+005.0851113
GO:0033290eukaryotic 48S preinitiation complex2.91e-021.00e+005.0851113
GO:0035371microtubule plus-end3.13e-021.00e+004.9781114
GO:0035267NuA4 histone acetyltransferase complex3.13e-021.00e+004.9781214
GO:0071480cellular response to gamma radiation3.13e-021.00e+004.9781114
GO:0006978DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator3.13e-021.00e+004.9781114
GO:0016282eukaryotic 43S preinitiation complex3.13e-021.00e+004.9781114
GO:0051298centrosome duplication3.13e-021.00e+004.9781114
GO:0032465regulation of cytokinesis3.13e-021.00e+004.9781114
GO:0048821erythrocyte development3.35e-021.00e+004.8781215
GO:0005852eukaryotic translation initiation factor 3 complex3.35e-021.00e+004.8781115
GO:0032435negative regulation of proteasomal ubiquitin-dependent protein catabolic process3.35e-021.00e+004.8781115
GO:0030131clathrin adaptor complex3.35e-021.00e+004.8781115
GO:0008585female gonad development3.35e-021.00e+004.8781115
GO:0033365protein localization to organelle3.79e-021.00e+004.6981117
GO:0007141male meiosis I3.79e-021.00e+004.6981117
GO:0001731formation of translation preinitiation complex3.79e-021.00e+004.6981117
GO:0019068virion assembly3.79e-021.00e+004.6981217
GO:0001556oocyte maturation3.79e-021.00e+004.6981117
GO:0000086G2/M transition of mitotic cell cycle3.85e-021.00e+002.68726137
GO:0010507negative regulation of autophagy4.00e-021.00e+004.6151118
GO:0043015gamma-tubulin binding4.00e-021.00e+004.6151218
GO:0006259DNA metabolic process4.22e-021.00e+004.5371119
GO:0010165response to X-ray4.22e-021.00e+004.5371119
GO:0017134fibroblast growth factor binding4.22e-021.00e+004.5371219
GO:0000082G1/S transition of mitotic cell cycle4.53e-021.00e+002.556211150
GO:0043021ribonucleoprotein complex binding4.66e-021.00e+004.3931121
GO:0007369gastrulation4.66e-021.00e+004.3931121
GO:0000793condensed chromosome4.66e-021.00e+004.3931221
GO:0007220Notch receptor processing4.87e-021.00e+004.3261222
GO:0007052mitotic spindle organization4.87e-021.00e+004.3261122
GO:0005198structural molecule activity5.03e-021.00e+002.47225159
GO:0051297centrosome organization5.09e-021.00e+004.2611223
GO:0045787positive regulation of cell cycle5.09e-021.00e+004.2611223
GO:0006611protein export from nucleus5.52e-021.00e+004.1411125
GO:0070423nucleotide-binding oligomerization domain containing signaling pathway5.52e-021.00e+004.1411225
GO:0007569cell aging5.52e-021.00e+004.1411125
GO:0045296cadherin binding5.52e-021.00e+004.1411125
GO:0005978glycogen biosynthetic process5.73e-021.00e+004.0851226
GO:0045931positive regulation of mitotic cell cycle5.73e-021.00e+004.0851226
GO:0061418regulation of transcription from RNA polymerase II promoter in response to hypoxia5.73e-021.00e+004.0851226
GO:0007420brain development5.78e-021.00e+002.35923172
GO:0008284positive regulation of cell proliferation5.86e-021.00e+001.75537392
GO:0045184establishment of protein localization5.95e-021.00e+004.0301227
GO:0019904protein domain specific binding6.33e-021.00e+002.28523181
GO:0010332response to gamma radiation6.38e-021.00e+003.9271229
GO:0042771intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator6.59e-021.00e+003.8781130
GO:0007093mitotic cell cycle checkpoint6.80e-021.00e+003.8311231
GO:0032480negative regulation of type I interferon production7.01e-021.00e+003.7851232
GO:0033077T cell differentiation in thymus7.22e-021.00e+003.7411133
GO:0043066negative regulation of apoptotic process7.42e-021.00e+001.612314433
GO:0001890placenta development7.43e-021.00e+003.6981134
GO:0003924GTPase activity7.72e-021.00e+002.12026203
GO:0034332adherens junction organization7.85e-021.00e+003.6151436
GO:0042059negative regulation of epidermal growth factor receptor signaling pathway7.85e-021.00e+003.6151336
GO:0006446regulation of translational initiation7.85e-021.00e+003.6151236
GO:0030218erythrocyte differentiation8.27e-021.00e+003.5371238
GO:0050681androgen receptor binding8.27e-021.00e+003.5371238
GO:0032092positive regulation of protein binding8.48e-021.00e+003.5001139
GO:0006184GTP catabolic process8.86e-021.00e+002.00426220
GO:0007249I-kappaB kinase/NF-kappaB signaling8.90e-021.00e+003.4271441
GO:0030521androgen receptor signaling pathway8.90e-021.00e+003.4271341
GO:0035872nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway9.31e-021.00e+003.3591243
GO:0004402histone acetyltransferase activity9.31e-021.00e+003.3591143
GO:0007286spermatid development9.52e-021.00e+003.3261144
GO:0019221cytokine-mediated signaling pathway9.55e-021.00e+001.93925230
GO:0043966histone H3 acetylation9.72e-021.00e+003.2931145
GO:0045893positive regulation of transcription, DNA-templated9.74e-021.00e+001.44238487
GO:0044297cell body9.93e-021.00e+003.2611146
GO:0045727positive regulation of translation9.93e-021.00e+003.2611146
GO:0008344adult locomotory behavior1.01e-011.00e+003.2301247
GO:0005634nucleus1.02e-011.00e+000.45515664828
GO:0019003GDP binding1.03e-011.00e+003.2001148
GO:0040008regulation of growth1.09e-011.00e+003.1131151
GO:0000910cytokinesis1.09e-011.00e+003.1131251
GO:0007254JNK cascade1.09e-011.00e+003.1131351
GO:0004197cysteine-type endopeptidase activity1.11e-011.00e+003.0851252
GO:0030666endocytic vesicle membrane1.16e-011.00e+003.0301254
GO:0051403stress-activated MAPK cascade1.16e-011.00e+003.0301454
GO:0006281DNA repair1.20e-011.00e+001.74125264
GO:0000724double-strand break repair via homologous recombination1.22e-011.00e+002.9521257
GO:0030097hemopoiesis1.24e-011.00e+002.9271158
GO:0045216cell-cell junction organization1.26e-011.00e+002.9021259
GO:0005643nuclear pore1.26e-011.00e+002.9021159
GO:0043065positive regulation of apoptotic process1.28e-011.00e+001.68726274
GO:0032481positive regulation of type I interferon production1.30e-011.00e+002.8541361
GO:0006302double-strand break repair1.31e-011.00e+002.8311262
GO:0007059chromosome segregation1.35e-011.00e+002.7851364
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathway1.35e-011.00e+002.7851264
GO:0051436negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.37e-011.00e+002.7631665
GO:0034166toll-like receptor 10 signaling pathway1.37e-011.00e+002.7631565
GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest1.37e-011.00e+002.7631665
GO:0034146toll-like receptor 5 signaling pathway1.37e-011.00e+002.7631565
GO:0005882intermediate filament1.39e-011.00e+002.7411366
GO:0043202lysosomal lumen1.39e-011.00e+002.7411166
GO:0030141secretory granule1.41e-011.00e+002.7191267
GO:0006289nucleotide-excision repair1.45e-011.00e+002.6761169
GO:0003697single-stranded DNA binding1.45e-011.00e+002.6761469
GO:0018105peptidyl-serine phosphorylation1.45e-011.00e+002.6761569
GO:0051437positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.47e-011.00e+002.6561870
GO:0043234protein complex1.48e-011.00e+001.55629300
GO:0038123toll-like receptor TLR1:TLR2 signaling pathway1.49e-011.00e+002.6351571
GO:0034329cell junction assembly1.49e-011.00e+002.6351271
GO:0038124toll-like receptor TLR6:TLR2 signaling pathway1.49e-011.00e+002.6351571
GO:0034162toll-like receptor 9 signaling pathway1.51e-011.00e+002.6151572
GO:0034134toll-like receptor 2 signaling pathway1.53e-011.00e+002.5951573
GO:0002479antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent1.53e-011.00e+002.5951673
GO:0000785chromatin1.53e-011.00e+002.5951273
GO:0002020protease binding1.55e-011.00e+002.5761174
GO:0051439regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle1.55e-011.00e+002.5761874
GO:0035666TRIF-dependent toll-like receptor signaling pathway1.59e-011.00e+002.5371576
GO:0008584male gonad development1.61e-011.00e+002.5181177
GO:0042590antigen processing and presentation of exogenous peptide antigen via MHC class I1.61e-011.00e+002.5181677
GO:0002756MyD88-independent toll-like receptor signaling pathway1.63e-011.00e+002.5001578
GO:0019901protein kinase binding1.64e-011.00e+001.46329320
GO:0071013catalytic step 2 spliceosome1.65e-011.00e+002.4811179
GO:0031145anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process1.65e-011.00e+002.4811879
GO:0002755MyD88-dependent toll-like receptor signaling pathway1.66e-011.00e+002.4631580
GO:0034138toll-like receptor 3 signaling pathway1.66e-011.00e+002.4631580
GO:0031902late endosome membrane1.66e-011.00e+002.4631180
GO:0005525GTP binding1.70e-011.00e+001.42726328
GO:0043197dendritic spine1.72e-011.00e+002.4101283
GO:0005179hormone activity1.74e-011.00e+002.3931184
GO:0003682chromatin binding1.75e-011.00e+001.40124334
GO:0005813centrosome1.79e-011.00e+001.38029339
GO:0050852T cell receptor signaling pathway1.81e-011.00e+002.3261288
GO:0090090negative regulation of canonical Wnt signaling pathway1.81e-011.00e+002.3261388
GO:0042593glucose homeostasis1.83e-011.00e+002.3091189
GO:0000187activation of MAPK activity1.85e-011.00e+002.2931390
GO:0000922spindle pole1.87e-011.00e+002.2771591
GO:0016363nuclear matrix1.89e-011.00e+002.2611492
GO:0016337single organismal cell-cell adhesion1.89e-011.00e+002.2611292
GO:0019886antigen processing and presentation of exogenous peptide antigen via MHC class II1.89e-011.00e+002.2611392
GO:0042470melanosome1.89e-011.00e+002.2611292
GO:0005200structural constituent of cytoskeleton1.91e-011.00e+002.2461693
GO:0002474antigen processing and presentation of peptide antigen via MHC class I1.93e-011.00e+002.2301794
GO:0034142toll-like receptor 4 signaling pathway1.96e-011.00e+002.2001596
GO:0030426growth cone1.98e-011.00e+002.1851397
GO:0071456cellular response to hypoxia2.00e-011.00e+002.1701398
GO:0016568chromatin modification2.02e-011.00e+002.1561299
GO:0051726regulation of cell cycle2.07e-011.00e+002.11312102
GO:0030496midbody2.20e-011.00e+002.01714109
GO:0002224toll-like receptor signaling pathway2.20e-011.00e+002.01715109
GO:0015630microtubule cytoskeleton2.25e-011.00e+001.97814112
GO:0000278mitotic cell cycle2.28e-011.00e+001.148216398
GO:0097190apoptotic signaling pathway2.32e-011.00e+001.92713116
GO:0000209protein polyubiquitination2.32e-011.00e+001.92717116
GO:0006006glucose metabolic process2.37e-011.00e+001.89014119
GO:0006325chromatin organization2.44e-011.00e+001.84212123
GO:0051092positive regulation of NF-kappaB transcription factor activity2.48e-011.00e+001.81913125
GO:0007219Notch signaling pathway2.48e-011.00e+001.81914125
GO:0030027lamellipodium2.56e-011.00e+001.76313130
GO:0007179transforming growth factor beta receptor signaling pathway2.56e-011.00e+001.76314130
GO:0009615response to virus2.60e-011.00e+001.74114132
GO:0031982vesicle2.63e-011.00e+001.71912134
GO:0045202synapse2.73e-011.00e+001.65611140
GO:0016055Wnt signaling pathway2.75e-011.00e+001.64513141
GO:0005911cell-cell junction2.77e-011.00e+001.63512142
GO:0008286insulin receptor signaling pathway2.80e-011.00e+001.61514144
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling2.86e-011.00e+001.57613148
GO:0042981regulation of apoptotic process2.91e-011.00e+001.54717151
GO:0010008endosome membrane3.01e-011.00e+001.49012157
GO:0006974cellular response to DNA damage stimulus3.03e-011.00e+001.48113158
GO:0008543fibroblast growth factor receptor signaling pathway3.04e-011.00e+001.47213159
GO:0008022protein C-terminus binding3.07e-011.00e+001.45414161
GO:0000398mRNA splicing, via spliceosome3.14e-011.00e+001.41912165
GO:0034220ion transmembrane transport3.17e-011.00e+001.40112167
GO:0038095Fc-epsilon receptor signaling pathway3.23e-011.00e+001.36713171
GO:0016607nuclear speck3.29e-011.00e+001.33412175
GO:0007049cell cycle3.32e-011.00e+001.31714177
GO:0048471perinuclear region of cytoplasm3.33e-011.00e+000.75429523
GO:0005764lysosome3.40e-011.00e+001.27712182
GO:0006367transcription initiation from RNA polymerase II promoter3.43e-011.00e+001.26115184
GO:0007173epidermal growth factor receptor signaling pathway3.53e-011.00e+001.20815191
GO:0001701in utero embryonic development3.81e-011.00e+001.07112210
GO:0000122negative regulation of transcription from RNA polymerase II promoter3.88e-011.00e+000.58329589
GO:0003713transcription coactivator activity4.21e-011.00e+000.88416239
GO:0030425dendrite4.22e-011.00e+000.87813240
GO:0005102receptor binding4.58e-011.00e+000.71912268
GO:0000166nucleotide binding4.63e-011.00e+000.69812272
GO:0048011neurotrophin TRK receptor signaling pathway4.65e-011.00e+000.69215273
GO:0005975carbohydrate metabolic process4.66e-011.00e+000.68713274
GO:0007283spermatogenesis4.68e-011.00e+000.67612276
GO:0019899enzyme binding4.83e-011.00e+000.61515288
GO:0007264small GTPase mediated signal transduction4.85e-011.00e+000.60517290
GO:0006351transcription, DNA-templated4.90e-011.00e+000.1554171585
GO:0004674protein serine/threonine kinase activity5.11e-011.00e+000.50016312
GO:0035556intracellular signal transduction5.16e-011.00e+000.47715317
GO:0005575cellular_component5.22e-011.00e+000.45412322
GO:0030154cell differentiation5.25e-011.00e+000.44113325
GO:0008283cell proliferation5.32e-011.00e+000.41414331
GO:0043231intracellular membrane-bounded organelle5.33e-011.00e+000.41013332
GO:0007275multicellular organismal development5.46e-011.00e+000.35912344
GO:0015031protein transport5.59e-011.00e+000.30514357
GO:0007155cell adhesion5.86e-011.00e+000.20013384
GO:0003677DNA binding6.01e-011.00e+00-0.0303141351
GO:0006508proteolysis6.10e-011.00e+000.10612410
GO:0008150biological_process6.52e-011.00e+00-0.05713459
GO:0046872metal ion binding6.57e-011.00e+00-0.1473141465
GO:0006468protein phosphorylation6.59e-011.00e+00-0.08216467
GO:0055085transmembrane transport6.94e-011.00e+00-0.22113514
GO:0006355regulation of transcription, DNA-templated7.24e-011.00e+00-0.3242101104
GO:0006915apoptotic process7.33e-011.00e+00-0.37219571
GO:0005783endoplasmic reticulum7.56e-011.00e+00-0.46816610
GO:0045087innate immune response7.60e-011.00e+00-0.482111616
GO:0005794Golgi apparatus7.78e-011.00e+00-0.55918650
GO:0044281small molecule metabolic process8.04e-011.00e+00-0.5542161295
GO:0003700sequence-specific DNA binding transcription factor activity8.24e-011.00e+00-0.76219748
GO:0045944positive regulation of transcription from RNA polymerase II promoter8.49e-011.00e+00-0.879111811
GO:0007165signal transduction8.92e-011.00e+00-1.10717950
GO:0005615extracellular space9.06e-011.00e+00-1.195131010
GO:0005739mitochondrion9.14e-011.00e+00-1.2461101046
GO:0005524ATP binding9.60e-011.00e+00-1.6181191354
GO:0005886plasma membrane9.92e-011.00e+00-1.6842242834