reg-snw-90850

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.200	2.87e-07	4.68e-02	3.55e-02

chia-screen-data-Fav-reg-snw-90850 subnetwork

Genes (12)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
OTUB1	55611	4	-1.774	2.268	45	-	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
FTSJ1	24140	43	-2.463	2.689	35	-	Yes	Yes
RANGAP1	5905	3	-1.596	2.303	74	-	-	-
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
CIZ1	25792	1	-1.450	2.200	23	TF	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
SF3A2	8175	3	-1.845	2.472	17	TF	-	-
DRG2	1819	15	-2.526	2.492	11	-	Yes	-
SYMPK	8189	11	-1.890	2.492	51	TF	-	-
[ ZNF598 ]	90850	1	-1.340	2.200	36	TF	-	-
SF3A1	10291	3	-2.787	2.472	8	-	Yes	Yes

Interactions (16)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DRG2	1819	SYMPK	8189	pd	<	reg.ITFP.txt: no annot
VARS	7407	FTSJ1	24140	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
SYMPK	8189	OTUB1	55611	pd	>	reg.ITFP.txt: no annot
SYMPK	8189	CIZ1	25792	pd	<>	reg.ITFP.txt: no annot
FTSJ1	24140	ZNF598	90850	pd	<	reg.ITFP.txt: no annot
RANGAP1	5905	ZNF598	90850	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
CIZ1	25792	ZNF598	90850	pd	<>	reg.ITFP.txt: no annot
SF3A2	8175	SF3A1	10291	pd	>	reg.ITFP.txt: no annot
SF3A1	10291	CIZ1	25792	pd	<	reg.ITFP.txt: no annot
SYMPK	8189	ZNF598	90850	pd	<>	reg.ITFP.txt: no annot
RANGAP1	5905	VARS	7407	pd	<	reg.ITFP.txt: no annot
SF3A2	8175	ZNF598	90850	pd	<>	reg.ITFP.txt: no annot
SF3A2	8175	CIZ1	25792	pd	<>	reg.ITFP.txt: no annot
OTUB1	55611	ZNF598	90850	pd	<	reg.ITFP.txt: no annot

Related GO terms (87)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000389	mRNA 3'-splice site recognition	8.30e-06	8.10e-02	8.668	2	2	4
GO:0004832	valine-tRNA ligase activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0002128	tRNA nucleoside ribose methylation	1.23e-03	1.00e+00	9.668	1	1	1
GO:0006438	valyl-tRNA aminoacylation	1.23e-03	1.00e+00	9.668	1	1	1
GO:0005098	Ran GTPase activator activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0008175	tRNA methyltransferase activity	1.23e-03	1.00e+00	9.668	1	1	1
GO:0005681	spliceosomal complex	1.98e-03	1.00e+00	4.887	2	8	55
GO:0071013	catalytic step 2 spliceosome	2.43e-03	1.00e+00	4.738	2	5	61
GO:0019784	NEDD8-specific protease activity	2.46e-03	1.00e+00	8.668	1	1	2
GO:0005684	U2-type spliceosomal complex	2.46e-03	1.00e+00	8.668	1	2	2
GO:1901315	negative regulation of histone H2A K63-linked ubiquitination	3.68e-03	1.00e+00	8.083	1	2	3
GO:0032853	positive regulation of Ran GTPase activity	3.68e-03	1.00e+00	8.083	1	1	3
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	6.13e-03	1.00e+00	7.347	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	6.13e-03	1.00e+00	7.347	1	1	5
GO:2000780	negative regulation of double-strand break repair	6.13e-03	1.00e+00	7.347	1	2	5
GO:0050847	progesterone receptor signaling pathway	7.35e-03	1.00e+00	7.083	1	2	6
GO:0002181	cytoplasmic translation	7.35e-03	1.00e+00	7.083	1	1	6
GO:0046826	negative regulation of protein export from nucleus	7.35e-03	1.00e+00	7.083	1	1	6
GO:0006397	mRNA processing	7.71e-03	1.00e+00	3.887	2	12	110
GO:0010944	negative regulation of transcription by competitive promoter binding	9.79e-03	1.00e+00	6.668	1	1	8
GO:0010388	cullin deneddylation	9.79e-03	1.00e+00	6.668	1	4	8
GO:0008242	omega peptidase activity	9.79e-03	1.00e+00	6.668	1	1	8
GO:0006450	regulation of translational fidelity	9.79e-03	1.00e+00	6.668	1	1	8
GO:0000398	mRNA splicing, via spliceosome	1.03e-02	1.00e+00	3.668	2	15	128
GO:0071354	cellular response to interleukin-6	1.10e-02	1.00e+00	6.499	1	1	9
GO:0005095	GTPase inhibitor activity	1.22e-02	1.00e+00	6.347	1	1	10
GO:0035307	positive regulation of protein dephosphorylation	1.22e-02	1.00e+00	6.347	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.34e-02	1.00e+00	6.209	1	4	11
GO:0071108	protein K48-linked deubiquitination	1.59e-02	1.00e+00	5.968	1	1	13
GO:0008380	RNA splicing	1.68e-02	1.00e+00	3.302	2	21	165
GO:0016575	histone deacetylation	1.71e-02	1.00e+00	5.861	1	2	14
GO:0005654	nucleoplasm	1.77e-02	1.00e+00	1.894	4	68	876
GO:0000188	inactivation of MAPK activity	1.83e-02	1.00e+00	5.762	1	1	15
GO:0030532	small nuclear ribonucleoprotein complex	2.07e-02	1.00e+00	5.581	1	1	17
GO:0005737	cytoplasm	2.16e-02	1.00e+00	1.113	7	127	2633
GO:0006378	mRNA polyadenylation	2.19e-02	1.00e+00	5.499	1	3	18
GO:0071897	DNA biosynthetic process	2.43e-02	1.00e+00	5.347	1	2	20
GO:0010467	gene expression	2.48e-02	1.00e+00	2.190	3	49	535
GO:0002376	immune system process	2.79e-02	1.00e+00	5.145	1	2	23
GO:0008180	COP9 signalosome	2.91e-02	1.00e+00	5.083	1	6	24
GO:0006418	tRNA aminoacylation for protein translation	3.51e-02	1.00e+00	4.810	1	4	29
GO:0007165	signal transduction	3.61e-02	1.00e+00	1.982	3	24	618
GO:0043130	ubiquitin binding	3.63e-02	1.00e+00	4.762	1	3	30
GO:0007254	JNK cascade	4.10e-02	1.00e+00	4.581	1	1	34
GO:0005739	mitochondrion	4.26e-02	1.00e+00	1.889	3	32	659
GO:0008270	zinc ion binding	5.45e-02	1.00e+00	1.748	3	39	727
GO:0004843	ubiquitin-specific protease activity	5.51e-02	1.00e+00	4.145	1	2	46
GO:0005643	nuclear pore	6.09e-02	1.00e+00	3.996	1	12	51
GO:0000776	kinetochore	6.56e-02	1.00e+00	3.887	1	8	55
GO:0000777	condensed chromosome kinetochore	6.79e-02	1.00e+00	3.836	1	6	57
GO:0044822	poly(A) RNA binding	6.88e-02	1.00e+00	1.611	3	45	799
GO:0042826	histone deacetylase binding	6.90e-02	1.00e+00	3.810	1	5	58
GO:0005923	tight junction	7.59e-02	1.00e+00	3.668	1	2	64
GO:0003676	nucleic acid binding	7.82e-02	1.00e+00	3.624	1	4	66
GO:0005515	protein binding	7.83e-02	1.00e+00	0.659	8	198	4124
GO:0000922	spindle pole	8.05e-02	1.00e+00	3.581	1	4	68
GO:0030308	negative regulation of cell growth	8.28e-02	1.00e+00	3.539	1	3	70
GO:0001649	osteoblast differentiation	8.73e-02	1.00e+00	3.459	1	5	74
GO:0042981	regulation of apoptotic process	1.29e-01	1.00e+00	2.861	1	4	112
GO:0007049	cell cycle	1.33e-01	1.00e+00	2.823	1	8	115
GO:0006974	cellular response to DNA damage stimulus	1.39e-01	1.00e+00	2.750	1	11	121
GO:0031965	nuclear membrane	1.49e-01	1.00e+00	2.646	1	8	130
GO:0031625	ubiquitin protein ligase binding	1.57e-01	1.00e+00	2.560	1	7	138
GO:0044212	transcription regulatory region DNA binding	1.62e-01	1.00e+00	2.509	1	13	143
GO:0005856	cytoskeleton	2.10e-01	1.00e+00	2.099	1	8	190
GO:0005743	mitochondrial inner membrane	2.17e-01	1.00e+00	2.046	1	9	197
GO:0005525	GTP binding	2.17e-01	1.00e+00	2.046	1	12	197
GO:0006281	DNA repair	2.23e-01	1.00e+00	2.003	1	24	203
GO:0019899	enzyme binding	2.30e-01	1.00e+00	1.954	1	7	210
GO:0007155	cell adhesion	2.62e-01	1.00e+00	1.738	1	8	244
GO:0003723	RNA binding	2.65e-01	1.00e+00	1.720	1	22	247
GO:0006508	proteolysis	2.80e-01	1.00e+00	1.624	1	11	264
GO:0008285	negative regulation of cell proliferation	2.92e-01	1.00e+00	1.555	1	11	277
GO:0000278	mitotic cell cycle	3.25e-01	1.00e+00	1.374	1	28	314
GO:0045892	negative regulation of transcription, DNA-templated	3.27e-01	1.00e+00	1.360	1	17	317
GO:0048471	perinuclear region of cytoplasm	3.50e-01	1.00e+00	1.242	1	11	344
GO:0005634	nucleus	3.66e-01	1.00e+00	0.326	5	158	3246
GO:0045893	positive regulation of transcription, DNA-templated	3.77e-01	1.00e+00	1.110	1	21	377
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	4.37e-01	1.00e+00	0.836	1	29	456
GO:0016020	membrane	4.47e-01	1.00e+00	0.431	2	56	1207
GO:0005730	nucleolus	4.52e-01	1.00e+00	0.419	2	74	1217
GO:0005887	integral component of plasma membrane	5.17e-01	1.00e+00	0.501	1	8	575
GO:0006355	regulation of transcription, DNA-templated	5.99e-01	1.00e+00	0.187	1	31	715
GO:0070062	extracellular vesicular exosome	6.24e-01	1.00e+00	-0.012	2	51	1641
GO:0005829	cytosol	6.74e-01	1.00e+00	-0.135	2	88	1787
GO:0005524	ATP binding	6.83e-01	1.00e+00	-0.132	1	37	892
GO:0005886	plasma membrane	9.11e-01	1.00e+00	-1.132	1	46	1784

chia-Fav

reg-snw-90850

Statistics

Genes (12)

Interactions (16)

Related GO terms (87)