reg-snw-908

Statistics

Dataset Score p-value 1 p-value 2 p-value 3
chia-screen-data-Fav 2.244 1.71e-07 3.57e-02 2.74e-02
chia-screen-data-Fav-reg-snw-908 subnetwork

Genes (11)

Gene Symbol Entrez Gene ID Frequency chia-screen-data-Fav gene score Best subnetwork score Degree Transcription factor Chia-Hits Primary Chia-Hits Secondary
NDUFA4L2 56901 44-2.4772.45921-Yes-
FBXL6 26233 28-2.2532.68922-Yes-
CENPA 1058 27-2.1852.393205TFYes-
SYNCRIP 10492 42-2.4012.503144TFYesYes
SUV39H2 79723 27-2.3072.41021-YesYes
FTSJ1 24140 43-2.4632.68935-YesYes
[ CCT6A ] 908 1-1.6662.24445---
EIF2S1 1965 5-1.8012.41063TF--
ETF1 2107 35-2.8292.5036-YesYes
GSPT1 2935 32-2.3132.50317-YesYes
NOLC1 9221 15-1.9852.503113TF--

Interactions (13)

Gene Symbol 1 Entrez Gene ID 1 Gene Symbol 2 Entrez Gene ID 2 Type Direction Origin databases / Sources
EIF2S1 1965 ETF1 2107 pd > reg.ITFP.txt: no annot
CENPA 1058 FBXL6 26233 pd > reg.ITFP.txt: no annot
NOLC1 9221 FTSJ1 24140 pd > reg.ITFP.txt: no annot
GSPT1 2935 NOLC1 9221 pd < reg.ITFP.txt: no annot
CENPA 1058 SUV39H2 79723 pd > reg.ITFP.txt: no annot
ETF1 2107 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
GSPT1 2935 SYNCRIP 10492 pd < reg.ITFP.txt: no annot
CCT6A 908 NOLC1 9221 pd < reg.ITFP.txt: no annot
EIF2S1 1965 SYNCRIP 10492 pd <> reg.ITFP.txt: no annot
CCT6A 908 CENPA 1058 pd < reg.ITFP.txt: no annot
SYNCRIP 10492 SUV39H2 79723 pd > reg.ITFP.txt: no annot
CCT6A 908 EIF2S1 1965 pd < reg.ITFP.txt: no annot
CENPA 1058 NDUFA4L2 56901 pd > reg.ITFP.txt: no annot

Related GO terms (106)

Accession number Name Hypergeometric test Corrected p-value Enrichment ratio Occurrence in subnetwork Occurrences in all snw genes Occurrences in all int/reg genes
GO:0003747translation release factor activity1.15e-061.13e-029.794222
GO:0006479protein methylation6.31e-056.16e-017.3352211
GO:0044822poly(A) RNA binding9.51e-059.28e-012.737645799
GO:0043022ribosome binding1.55e-041.00e+006.7072217
GO:0000775chromosome, centromeric region9.24e-041.00e+005.4362641
GO:0000939condensed chromosome inner kinetochore1.13e-031.00e+009.794111
GO:0016149translation release factor activity, codon specific1.13e-031.00e+009.794111
GO:0008079translation termination factor activity1.13e-031.00e+009.794111
GO:0002128tRNA nucleoside ribose methylation1.13e-031.00e+009.794111
GO:0008175tRNA methyltransferase activity1.13e-031.00e+009.794111
GO:0006415translational termination2.17e-031.00e+004.8172263
GO:0043558regulation of translational initiation in response to stress2.25e-031.00e+008.794112
GO:0005850eukaryotic translation initiation factor 2 complex3.38e-031.00e+008.209123
GO:0036123histone H3-K9 dimethylation3.38e-031.00e+008.209113
GO:0000778condensed nuclear chromosome kinetochore3.38e-031.00e+008.209123
GO:0071459protein localization to chromosome, centromeric region3.38e-031.00e+008.209113
GO:0000184nuclear-transcribed mRNA catabolic process, nonsense-mediated decay3.82e-031.00e+004.4022584
GO:0006449regulation of translational termination4.50e-031.00e+007.794114
GO:0007000nucleolus organization4.50e-031.00e+007.794114
GO:0006333chromatin assembly or disassembly4.50e-031.00e+007.794114
GO:0036124histone H3-K9 trimethylation4.50e-031.00e+007.794124
GO:0097452GAIT complex4.50e-031.00e+007.794124
GO:0005851eukaryotic translation initiation factor 2B complex4.50e-031.00e+007.794124
GO:0071204histone pre-mRNA 3'end processing complex5.62e-031.00e+007.472115
GO:0070934CRD-mediated mRNA stabilization5.62e-031.00e+007.472125
GO:0044267cellular protein metabolic process6.18e-031.00e+002.920314352
GO:0002181cytoplasmic translation6.74e-031.00e+007.209116
GO:0070937CRD-mediated mRNA stability complex6.74e-031.00e+007.209126
GO:0042754negative regulation of circadian rhythm6.74e-031.00e+007.209126
GO:0046974histone methyltransferase activity (H3-K9 specific)6.74e-031.00e+007.209116
GO:0002199zona pellucida receptor complex7.86e-031.00e+006.987147
GO:0007140male meiosis7.86e-031.00e+006.987117
GO:0000780condensed nuclear chromosome, centromeric region7.86e-031.00e+006.987117
GO:0005832chaperonin-containing T-complex7.86e-031.00e+006.987147
GO:0051382kinetochore assembly7.86e-031.00e+006.987127
GO:0008143poly(A) binding1.12e-021.00e+006.4721210
GO:0000132establishment of mitotic spindle orientation1.34e-021.00e+006.2091212
GO:0006412translation1.63e-021.00e+003.318212178
GO:0007339binding of sperm to zona pellucida1.68e-021.00e+005.8871415
GO:0005525GTP binding1.98e-021.00e+003.172212197
GO:0005844polysome2.12e-021.00e+005.5461219
GO:0071346cellular response to interferon-gamma2.23e-021.00e+005.4721220
GO:0005720nuclear heterochromatin2.23e-021.00e+005.4721320
GO:0034080CENP-A containing nucleosome assembly2.23e-021.00e+005.4721220
GO:0051084'de novo' posttranslational protein folding2.45e-021.00e+005.3351422
GO:0000976transcription regulatory region sequence-specific DNA binding2.78e-021.00e+005.1501325
GO:0010494cytoplasmic stress granule2.89e-021.00e+005.0941426
GO:0003723RNA binding3.02e-021.00e+002.846222247
GO:0001669acrosomal vesicle3.11e-021.00e+004.9871128
GO:0003682chromatin binding3.13e-021.00e+002.817215252
GO:0015030Cajal body3.55e-021.00e+004.7941332
GO:0017148negative regulation of translation3.66e-021.00e+004.7501533
GO:0000786nucleosome3.77e-021.00e+004.7071234
GO:0044297cell body3.87e-021.00e+004.6651535
GO:0003743translation initiation factor activity4.09e-021.00e+004.5851837
GO:0005515protein binding4.12e-021.00e+000.78481984124
GO:0048511rhythmic process4.20e-021.00e+004.5461538
GO:0006396RNA processing4.42e-021.00e+004.4721440
GO:0006987activation of signaling protein activity involved in unfolded protein response5.17e-021.00e+004.2391147
GO:0006334nucleosome assembly5.60e-021.00e+004.1221451
GO:0006338chromatin remodeling6.03e-021.00e+004.0131755
GO:0000785chromatin6.45e-021.00e+003.9111659
GO:0030968endoplasmic reticulum unfolded protein response6.66e-021.00e+003.8631161
GO:0071013catalytic step 2 spliceosome6.66e-021.00e+003.8631561
GO:0006364rRNA processing7.30e-021.00e+003.7281267
GO:0051082unfolded protein binding7.61e-021.00e+003.6651570
GO:0001649osteoblast differentiation8.03e-021.00e+003.5851574
GO:0016032viral process8.12e-021.00e+002.053230428
GO:0071456cellular response to hypoxia8.24e-021.00e+003.5461276
GO:0030529ribonucleoprotein complex8.86e-021.00e+003.4361582
GO:0006457protein folding1.04e-011.00e+003.1941597
GO:0006413translational initiation1.06e-011.00e+003.1651699
GO:0046777protein autophosphorylation1.13e-011.00e+003.06613106
GO:0010467gene expression1.19e-011.00e+001.731249535
GO:0007049cell cycle1.22e-011.00e+002.94818115
GO:0005829cytosol1.25e-011.00e+000.9914881787
GO:0003924GTPase activity1.26e-011.00e+002.89917119
GO:0000082G1/S transition of mitotic cell cycle1.32e-011.00e+002.82814125
GO:0000398mRNA splicing, via spliceosome1.35e-011.00e+002.794115128
GO:0006184GTP catabolic process1.37e-011.00e+002.77217130
GO:0005622intracellular1.52e-011.00e+002.61412145
GO:0005874microtubule1.69e-011.00e+002.445110163
GO:0007067mitotic nuclear division1.71e-011.00e+002.42819165
GO:0008380RNA splicing1.71e-011.00e+002.428121165
GO:0016071mRNA metabolic process1.76e-011.00e+002.385110170
GO:0000166nucleotide binding1.81e-011.00e+002.335113176
GO:0004842ubiquitin-protein transferase activity1.84e-011.00e+002.310117179
GO:0016070RNA metabolic process1.93e-011.00e+002.239110188
GO:0016567protein ubiquitination1.93e-011.00e+002.239114188
GO:0030154cell differentiation2.07e-011.00e+002.12215204
GO:0005654nucleoplasm2.59e-011.00e+001.019268876
GO:0006508proteolysis2.60e-011.00e+001.750111264
GO:0046982protein heterodimerization activity2.61e-011.00e+001.744111265
GO:0005524ATP binding2.66e-011.00e+000.993237892
GO:0000278mitotic cell cycle3.02e-011.00e+001.499128314
GO:0045892negative regulation of transcription, DNA-templated3.05e-011.00e+001.486117317
GO:0005737cytoplasm3.42e-011.00e+000.43141272633
GO:0005783endoplasmic reticulum3.55e-011.00e+001.220112381
GO:0016020membrane4.02e-011.00e+000.5572561207
GO:0000122negative regulation of transcription from RNA polymerase II promoter4.09e-011.00e+000.961129456
GO:0008270zinc ion binding5.73e-011.00e+000.288139727
GO:0070062extracellular vesicular exosome5.74e-011.00e+000.1142511641
GO:0003677DNA binding6.75e-011.00e+00-0.093152947
GO:0006351transcription, DNA-templated7.23e-011.00e+00-0.2771471076
GO:0005634nucleus7.64e-011.00e+00-0.28631583246
GO:0005730nucleolus7.69e-011.00e+00-0.4551741217