reg-snw-54920

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.249	1.61e-07	3.45e-02	2.66e-02

chia-screen-data-Fav-reg-snw-54920 subnetwork

Genes (7)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
RNF40	9810	10	-2.082	2.492	38	TF	Yes	-
ETF1	2107	35	-2.829	2.503	6	-	Yes	Yes
TDP1	55775	5	-1.669	2.428	52	-	-	-
SYNCRIP	10492	42	-2.401	2.503	144	TF	Yes	Yes
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
TRAIP	10293	13	-2.546	2.454	30	TF	Yes	-
[ DUS2 ]	54920	1	-1.529	2.249	36	TF	-	-

Interactions (7)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
TRAIP	10293	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
DUS2	54920	TDP1	55775	pd	>	reg.ITFP.txt: no annot
RNF40	9810	DUS2	54920	pd	>	reg.ITFP.txt: no annot
ETF1	2107	SYNCRIP	10492	pd	<	reg.ITFP.txt: no annot
SYNCRIP	10492	TDP1	55775	pd	>	reg.ITFP.txt: no annot
SYNCRIP	10492	CPSF3	51692	pd	>	reg.ITFP.txt: no annot
CPSF3	51692	DUS2	54920	pd	<	reg.ITFP.txt: no annot

Related GO terms (87)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0003723	RNA binding	5.19e-04	1.00e+00	4.083	3	22	247
GO:0017005	3'-tyrosyl-DNA phosphodiesterase activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:0016149	translation release factor activity, codon specific	7.17e-04	1.00e+00	10.446	1	1	1
GO:0008079	translation termination factor activity	7.17e-04	1.00e+00	10.446	1	1	1
GO:0030529	ribonucleoprotein complex	1.42e-03	1.00e+00	5.088	2	5	82
GO:0003747	translation release factor activity	1.43e-03	1.00e+00	9.446	1	2	2
GO:0017150	tRNA dihydrouridine synthase activity	2.15e-03	1.00e+00	8.861	1	1	3
GO:0002943	tRNA dihydrouridine synthesis	2.15e-03	1.00e+00	8.861	1	1	3
GO:0005515	protein binding	2.39e-03	1.00e+00	1.244	7	198	4124
GO:0006449	regulation of translational termination	2.86e-03	1.00e+00	8.446	1	1	4
GO:0000012	single strand break repair	2.86e-03	1.00e+00	8.446	1	1	4
GO:0033503	HULC complex	2.86e-03	1.00e+00	8.446	1	1	4
GO:0097452	GAIT complex	2.86e-03	1.00e+00	8.446	1	2	4
GO:0000398	mRNA splicing, via spliceosome	3.43e-03	1.00e+00	4.446	2	15	128
GO:0004521	endoribonuclease activity	3.58e-03	1.00e+00	8.124	1	1	5
GO:0006398	histone mRNA 3'-end processing	3.58e-03	1.00e+00	8.124	1	1	5
GO:0071204	histone pre-mRNA 3'end processing complex	3.58e-03	1.00e+00	8.124	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	3.58e-03	1.00e+00	8.124	1	2	5
GO:0070937	CRD-mediated mRNA stability complex	4.29e-03	1.00e+00	7.861	1	2	6
GO:0016874	ligase activity	4.44e-03	1.00e+00	4.256	2	11	146
GO:0008409	5'-3' exonuclease activity	5.01e-03	1.00e+00	7.639	1	2	7
GO:0033523	histone H2B ubiquitination	5.01e-03	1.00e+00	7.639	1	1	7
GO:0008380	RNA splicing	5.64e-03	1.00e+00	4.080	2	21	165
GO:0010390	histone monoubiquitination	5.72e-03	1.00e+00	7.446	1	2	8
GO:0006379	mRNA cleavage	6.44e-03	1.00e+00	7.276	1	2	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	6.44e-03	1.00e+00	7.276	1	3	9
GO:0004842	ubiquitin-protein transferase activity	6.60e-03	1.00e+00	3.962	2	17	179
GO:0008143	poly(A) binding	7.15e-03	1.00e+00	7.124	1	2	10
GO:0006479	protein methylation	7.86e-03	1.00e+00	6.987	1	2	11
GO:0004527	exonuclease activity	8.57e-03	1.00e+00	6.861	1	4	12
GO:0017075	syntaxin-1 binding	9.28e-03	1.00e+00	6.746	1	1	13
GO:0004860	protein kinase inhibitor activity	1.07e-02	1.00e+00	6.539	1	1	15
GO:0043022	ribosome binding	1.21e-02	1.00e+00	6.359	1	2	17
GO:0006378	mRNA polyadenylation	1.28e-02	1.00e+00	6.276	1	3	18
GO:0060548	negative regulation of cell death	1.35e-02	1.00e+00	6.198	1	1	19
GO:0071346	cellular response to interferon-gamma	1.43e-02	1.00e+00	6.124	1	2	20
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	1.50e-02	1.00e+00	6.054	1	2	21
GO:0005057	receptor signaling protein activity	1.85e-02	1.00e+00	5.746	1	2	26
GO:0090305	nucleic acid phosphodiester bond hydrolysis	2.20e-02	1.00e+00	5.492	1	6	31
GO:0017148	negative regulation of translation	2.34e-02	1.00e+00	5.402	1	5	33
GO:0031124	mRNA 3'-end processing	2.48e-02	1.00e+00	5.317	1	4	35
GO:0050660	flavin adenine dinucleotide binding	2.69e-02	1.00e+00	5.198	1	1	38
GO:0006369	termination of RNA polymerase II transcription	2.69e-02	1.00e+00	5.198	1	5	38
GO:0005783	endoplasmic reticulum	2.80e-02	1.00e+00	2.872	2	12	381
GO:0006396	RNA processing	2.83e-02	1.00e+00	5.124	1	4	40
GO:0006406	mRNA export from nucleus	3.11e-02	1.00e+00	4.987	1	7	44
GO:0003725	double-stranded RNA binding	3.18e-02	1.00e+00	4.954	1	2	45
GO:0000151	ubiquitin ligase complex	3.39e-02	1.00e+00	4.861	1	4	48
GO:0006469	negative regulation of protein kinase activity	3.53e-02	1.00e+00	4.802	1	2	50
GO:0006302	double-strand break repair	3.67e-02	1.00e+00	4.746	1	5	52
GO:0003697	single-stranded DNA binding	4.02e-02	1.00e+00	4.613	1	4	57
GO:0071013	catalytic step 2 spliceosome	4.29e-02	1.00e+00	4.515	1	5	61
GO:0006415	translational termination	4.43e-02	1.00e+00	4.469	1	2	63
GO:0001649	osteoblast differentiation	5.19e-02	1.00e+00	4.237	1	5	74
GO:0010467	gene expression	5.24e-02	1.00e+00	2.383	2	49	535
GO:0003690	double-stranded DNA binding	5.80e-02	1.00e+00	4.071	1	6	83
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	5.87e-02	1.00e+00	4.054	1	5	84
GO:0006511	ubiquitin-dependent protein catabolic process	6.41e-02	1.00e+00	3.922	1	6	92
GO:0043005	neuron projection	7.83e-02	1.00e+00	3.626	1	6	113
GO:0032403	protein complex binding	8.96e-02	1.00e+00	3.424	1	5	130
GO:0008270	zinc ion binding	9.05e-02	1.00e+00	1.940	2	39	727
GO:0031625	ubiquitin protein ligase binding	9.49e-02	1.00e+00	3.338	1	7	138
GO:0044822	poly(A) RNA binding	1.07e-01	1.00e+00	1.804	2	45	799
GO:0016071	mRNA metabolic process	1.16e-01	1.00e+00	3.037	1	10	170
GO:0000166	nucleotide binding	1.20e-01	1.00e+00	2.987	1	13	176
GO:0006412	translation	1.21e-01	1.00e+00	2.970	1	12	178
GO:0005654	nucleoplasm	1.25e-01	1.00e+00	1.671	2	68	876
GO:0016070	RNA metabolic process	1.27e-01	1.00e+00	2.891	1	10	188
GO:0016567	protein ubiquitination	1.27e-01	1.00e+00	2.891	1	14	188
GO:0035556	intracellular signal transduction	1.34e-01	1.00e+00	2.809	1	5	199
GO:0006281	DNA repair	1.37e-01	1.00e+00	2.781	1	24	203
GO:0008283	cell proliferation	1.59e-01	1.00e+00	2.545	1	8	239
GO:0055114	oxidation-reduction process	2.01e-01	1.00e+00	2.179	1	9	308
GO:0016020	membrane	2.11e-01	1.00e+00	1.209	2	56	1207
GO:0006366	transcription from RNA polymerase II promoter	2.20e-01	1.00e+00	2.032	1	23	341
GO:0048471	perinuclear region of cytoplasm	2.22e-01	1.00e+00	2.020	1	11	344
GO:0044267	cellular protein metabolic process	2.27e-01	1.00e+00	1.987	1	14	352
GO:0006915	apoptotic process	2.60e-01	1.00e+00	1.763	1	15	411
GO:0042803	protein homodimerization activity	2.69e-01	1.00e+00	1.705	1	13	428
GO:0016032	viral process	2.69e-01	1.00e+00	1.705	1	30	428
GO:0005737	cytoplasm	2.85e-01	1.00e+00	0.669	3	127	2633
GO:0007165	signal transduction	3.67e-01	1.00e+00	1.175	1	24	618
GO:0005739	mitochondrion	3.87e-01	1.00e+00	1.082	1	32	659
GO:0005634	nucleus	4.27e-01	1.00e+00	0.367	3	158	3246
GO:0046872	metal ion binding	5.05e-01	1.00e+00	0.579	1	24	934
GO:0005730	nucleolus	6.06e-01	1.00e+00	0.197	1	74	1217
GO:0005829	cytosol	7.57e-01	1.00e+00	-0.357	1	88	1787

chia-Fav

reg-snw-54920

Statistics

Genes (7)

Interactions (7)

Related GO terms (87)