reg-snw-5425

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.393	2.68e-08	1.27e-02	1.07e-02

chia-screen-data-Fav-reg-snw-5425 subnetwork

Genes (9)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
EIF2S2	8894	40	-2.999	2.459	22	-	Yes	Yes
CENPA	1058	27	-2.185	2.393	205	TF	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
VARS	7407	60	-2.366	2.689	124	TF	Yes	-
COPS6	10980	4	-1.765	2.393	18	TF	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes
POLH	5429	36	-2.586	2.459	24	-	Yes	Yes
[ POLD2 ]	5425	1	-1.532	2.393	19	-	-	-
FBXO22	26263	36	-1.739	2.459	208	TF	-	-

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
POLD2	5425	VARS	7407	pd	<	reg.ITFP.txt: no annot
VARS	7407	FBXO22	26263	pd	<>	reg.ITFP.txt: no annot
GPS1	2873	POLD2	5425	pd	>	reg.ITFP.txt: no annot
PHB	5245	VARS	7407	pd	<	reg.ITFP.txt: no annot
PHB	5245	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
POLH	5429	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
CENPA	1058	POLD2	5425	pd	>	reg.ITFP.txt: no annot
EIF2S2	8894	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
POLD2	5425	FBXO22	26263	pd	<	reg.ITFP.txt: no annot
POLD2	5425	COPS6	10980	pd	<	reg.ITFP.txt: no annot

Related GO terms (97)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0010388	cullin deneddylation	2.11e-05	2.06e-01	8.083	2	4	8
GO:0003887	DNA-directed DNA polymerase activity	9.00e-05	8.79e-01	7.083	2	2	16
GO:0071897	DNA biosynthetic process	1.42e-04	1.00e+00	6.762	2	2	20
GO:0008180	COP9 signalosome	2.06e-04	1.00e+00	6.499	2	6	24
GO:0000939	condensed chromosome inner kinetochore	9.22e-04	1.00e+00	10.083	1	1	1
GO:0004832	valine-tRNA ligase activity	9.22e-04	1.00e+00	10.083	1	1	1
GO:0006438	valyl-tRNA aminoacylation	9.22e-04	1.00e+00	10.083	1	1	1
GO:0048742	regulation of skeletal muscle fiber development	1.84e-03	1.00e+00	9.083	1	1	2
GO:0002176	male germ cell proliferation	1.84e-03	1.00e+00	9.083	1	1	2
GO:0005850	eukaryotic translation initiation factor 2 complex	2.76e-03	1.00e+00	8.499	1	2	3
GO:0000778	condensed nuclear chromosome kinetochore	2.76e-03	1.00e+00	8.499	1	2	3
GO:0071459	protein localization to chromosome, centromeric region	2.76e-03	1.00e+00	8.499	1	1	3
GO:0006260	DNA replication	3.16e-03	1.00e+00	4.529	2	9	94
GO:0006290	pyrimidine dimer repair	3.68e-03	1.00e+00	8.083	1	2	4
GO:0006282	regulation of DNA repair	4.60e-03	1.00e+00	7.762	1	2	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	4.60e-03	1.00e+00	7.762	1	1	5
GO:0002161	aminoacyl-tRNA editing activity	4.60e-03	1.00e+00	7.762	1	1	5
GO:0050847	progesterone receptor signaling pathway	5.52e-03	1.00e+00	7.499	1	2	6
GO:0005654	nucleoplasm	5.61e-03	1.00e+00	2.309	4	68	876
GO:0000780	condensed nuclear chromosome, centromeric region	6.44e-03	1.00e+00	7.276	1	1	7
GO:0000731	DNA synthesis involved in DNA repair	6.44e-03	1.00e+00	7.276	1	1	7
GO:0006301	postreplication repair	6.44e-03	1.00e+00	7.276	1	2	7
GO:0051382	kinetochore assembly	6.44e-03	1.00e+00	7.276	1	2	7
GO:0010944	negative regulation of transcription by competitive promoter binding	7.35e-03	1.00e+00	7.083	1	1	8
GO:0006450	regulation of translational fidelity	7.35e-03	1.00e+00	7.083	1	1	8
GO:0010225	response to UV-C	8.27e-03	1.00e+00	6.914	1	2	9
GO:0071354	cellular response to interleukin-6	8.27e-03	1.00e+00	6.914	1	1	9
GO:2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	8.27e-03	1.00e+00	6.914	1	2	9
GO:0005095	GTPase inhibitor activity	9.18e-03	1.00e+00	6.762	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.01e-02	1.00e+00	6.624	1	4	11
GO:0000132	establishment of mitotic spindle orientation	1.10e-02	1.00e+00	6.499	1	2	12
GO:0016575	histone deacetylation	1.28e-02	1.00e+00	6.276	1	2	14
GO:0000188	inactivation of MAPK activity	1.37e-02	1.00e+00	6.177	1	1	15
GO:0008135	translation factor activity, nucleic acid binding	1.37e-02	1.00e+00	6.177	1	4	15
GO:0006281	DNA repair	1.41e-02	1.00e+00	3.418	2	24	203
GO:0006297	nucleotide-excision repair, DNA gap filling	1.65e-02	1.00e+00	5.914	1	1	18
GO:0006913	nucleocytoplasmic transport	1.83e-02	1.00e+00	5.762	1	2	20
GO:0032201	telomere maintenance via semi-conservative replication	1.83e-02	1.00e+00	5.762	1	1	20
GO:0034080	CENP-A containing nucleosome assembly	1.83e-02	1.00e+00	5.762	1	2	20
GO:0000722	telomere maintenance via recombination	2.01e-02	1.00e+00	5.624	1	1	22
GO:0009267	cellular response to starvation	2.37e-02	1.00e+00	5.383	1	1	26
GO:0006418	tRNA aminoacylation for protein translation	2.64e-02	1.00e+00	5.225	1	4	29
GO:0006271	DNA strand elongation involved in DNA replication	2.64e-02	1.00e+00	5.225	1	1	29
GO:0006284	base-excision repair	2.91e-02	1.00e+00	5.083	1	3	32
GO:0000786	nucleosome	3.09e-02	1.00e+00	4.996	1	2	34
GO:0007254	JNK cascade	3.09e-02	1.00e+00	4.996	1	1	34
GO:0000278	mitotic cell cycle	3.20e-02	1.00e+00	2.789	2	28	314
GO:0003743	translation initiation factor activity	3.36e-02	1.00e+00	4.874	1	8	37
GO:0005515	protein binding	3.44e-02	1.00e+00	0.881	7	198	4124
GO:0032436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	3.45e-02	1.00e+00	4.836	1	4	38
GO:0006283	transcription-coupled nucleotide-excision repair	3.63e-02	1.00e+00	4.762	1	6	40
GO:0003684	damaged DNA binding	3.72e-02	1.00e+00	4.726	1	1	41
GO:0000775	chromosome, centromeric region	3.72e-02	1.00e+00	4.726	1	6	41
GO:0005634	nucleus	4.18e-02	1.00e+00	1.004	6	158	3246
GO:0000723	telomere maintenance	4.25e-02	1.00e+00	4.529	1	2	47
GO:0006334	nucleosome assembly	4.61e-02	1.00e+00	4.411	1	4	51
GO:0006289	nucleotide-excision repair	4.78e-02	1.00e+00	4.356	1	6	53
GO:0008584	male gonad development	5.13e-02	1.00e+00	4.251	1	1	57
GO:0042826	histone deacetylase binding	5.22e-02	1.00e+00	4.225	1	5	58
GO:0006464	cellular protein modification process	5.49e-02	1.00e+00	4.153	1	4	61
GO:0016032	viral process	5.63e-02	1.00e+00	2.342	2	30	428
GO:0030018	Z disc	5.75e-02	1.00e+00	4.083	1	3	64
GO:0030308	negative regulation of cell growth	6.27e-02	1.00e+00	3.954	1	3	70
GO:0001649	osteoblast differentiation	6.62e-02	1.00e+00	3.874	1	5	74
GO:0006511	ubiquitin-dependent protein catabolic process	8.17e-02	1.00e+00	3.560	1	6	92
GO:0000209	protein polyubiquitination	8.17e-02	1.00e+00	3.560	1	6	92
GO:0010467	gene expression	8.35e-02	1.00e+00	2.020	2	49	535
GO:0006413	translational initiation	8.77e-02	1.00e+00	3.454	1	6	99
GO:0042981	regulation of apoptotic process	9.87e-02	1.00e+00	3.276	1	4	112
GO:0007049	cell cycle	1.01e-01	1.00e+00	3.238	1	8	115
GO:0005739	mitochondrion	1.19e-01	1.00e+00	1.719	2	32	659
GO:0044212	transcription regulatory region DNA binding	1.24e-01	1.00e+00	2.924	1	13	143
GO:0001701	in utero embryonic development	1.33e-01	1.00e+00	2.817	1	7	154
GO:0006412	translation	1.53e-01	1.00e+00	2.608	1	12	178
GO:0004842	ubiquitin-protein transferase activity	1.53e-01	1.00e+00	2.600	1	17	179
GO:0005743	mitochondrial inner membrane	1.68e-01	1.00e+00	2.461	1	9	197
GO:0019899	enzyme binding	1.78e-01	1.00e+00	2.369	1	7	210
GO:0003723	RNA binding	2.06e-01	1.00e+00	2.135	1	22	247
GO:0003682	chromatin binding	2.10e-01	1.00e+00	2.106	1	15	252
GO:0046872	metal ion binding	2.10e-01	1.00e+00	1.216	2	24	934
GO:0003677	DNA binding	2.15e-01	1.00e+00	1.196	2	52	947
GO:0005829	cytosol	2.18e-01	1.00e+00	0.865	3	88	1787
GO:0046982	protein heterodimerization activity	2.19e-01	1.00e+00	2.034	1	11	265
GO:0008285	negative regulation of cell proliferation	2.28e-01	1.00e+00	1.970	1	11	277
GO:0045892	negative regulation of transcription, DNA-templated	2.57e-01	1.00e+00	1.775	1	17	317
GO:0044267	cellular protein metabolic process	2.81e-01	1.00e+00	1.624	1	14	352
GO:0045893	positive regulation of transcription, DNA-templated	2.98e-01	1.00e+00	1.525	1	21	377
GO:0005730	nucleolus	3.11e-01	1.00e+00	0.834	2	74	1217
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.50e-01	1.00e+00	1.251	1	29	456
GO:0005887	integral component of plasma membrane	4.21e-01	1.00e+00	0.916	1	8	575
GO:0007165	signal transduction	4.45e-01	1.00e+00	0.812	1	24	618
GO:0005737	cytoplasm	4.54e-01	1.00e+00	0.306	3	127	2633
GO:0070062	extracellular vesicular exosome	4.62e-01	1.00e+00	0.403	2	51	1641
GO:0006355	regulation of transcription, DNA-templated	4.96e-01	1.00e+00	0.602	1	31	715
GO:0044822	poly(A) RNA binding	5.36e-01	1.00e+00	0.441	1	45	799
GO:0005524	ATP binding	5.78e-01	1.00e+00	0.283	1	37	892
GO:0016020	membrane	6.95e-01	1.00e+00	-0.154	1	56	1207

chia-Fav

reg-snw-5425

Statistics

Genes (9)

Interactions (11)

Related GO terms (97)