reg-snw-4927

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.292	9.59e-08	2.61e-02	2.05e-02

chia-screen-data-Fav-reg-snw-4927 subnetwork

Genes (10)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
KARS	3735	12	-1.759	2.428	123	TF	-	-
CENPA	1058	27	-2.185	2.393	205	TF	Yes	-
[ NUP88 ]	4927	1	-1.654	2.292	14	-	-	-
PHB2	11331	17	-2.236	2.449	11	-	Yes	-
COPS3	8533	8	-1.873	2.435	79	TF	-	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
EIF2B3	8891	8	-2.546	2.435	4	-	Yes	Yes
NOLC1	9221	15	-1.985	2.503	113	TF	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes

Interactions (11)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
NUP88	4927	COPS3	8533	pd	<	reg.ITFP.txt: no annot
KARS	3735	NOLC1	9221	pd	<>	reg.ITFP.txt: no annot
CENPA	1058	KARS	3735	pd	<>	reg.ITFP.txt: no annot
KARS	3735	PHB2	11331	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	NOLC1	9221	pd	<	reg.ITFP.txt: no annot
KARS	3735	PHB	5245	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	KARS	3735	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
COPS3	8533	EIF2B3	8891	pd	>	reg.ITFP.txt: no annot
KARS	3735	NUP88	4927	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB2	11331	pd	>	reg.ITFP.txt: no annot

Related GO terms (118)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0010388	cullin deneddylation	2.63e-05	2.57e-01	7.931	2	4	8
GO:0008180	COP9 signalosome	2.57e-04	1.00e+00	6.347	2	6	24
GO:0000939	condensed chromosome inner kinetochore	1.02e-03	1.00e+00	9.931	1	1	1
GO:0006430	lysyl-tRNA aminoacylation	1.02e-03	1.00e+00	9.931	1	1	1
GO:0004824	lysine-tRNA ligase activity	1.02e-03	1.00e+00	9.931	1	1	1
GO:0015966	diadenosine tetraphosphate biosynthetic process	2.05e-03	1.00e+00	8.931	1	1	2
GO:0051716	cellular response to stimulus	2.05e-03	1.00e+00	8.931	1	1	2
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	2.05e-03	1.00e+00	8.931	1	1	2
GO:0003747	translation release factor activity	2.05e-03	1.00e+00	8.931	1	2	2
GO:0005515	protein binding	2.64e-03	1.00e+00	1.092	9	198	4124
GO:0000778	condensed nuclear chromosome kinetochore	3.07e-03	1.00e+00	8.347	1	2	3
GO:0071459	protein localization to chromosome, centromeric region	3.07e-03	1.00e+00	8.347	1	1	3
GO:0032057	negative regulation of translational initiation in response to stress	4.09e-03	1.00e+00	7.931	1	1	4
GO:0007000	nucleolus organization	4.09e-03	1.00e+00	7.931	1	1	4
GO:0005851	eukaryotic translation initiation factor 2B complex	4.09e-03	1.00e+00	7.931	1	2	4
GO:0016779	nucleotidyltransferase activity	4.09e-03	1.00e+00	7.931	1	1	4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	4.09e-03	1.00e+00	7.931	1	1	4
GO:0060744	mammary gland branching involved in thelarche	5.11e-03	1.00e+00	7.610	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	5.11e-03	1.00e+00	7.610	1	1	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	5.11e-03	1.00e+00	7.610	1	1	5
GO:0007049	cell cycle	5.82e-03	1.00e+00	4.086	2	8	115
GO:0050847	progesterone receptor signaling pathway	6.13e-03	1.00e+00	7.347	1	2	6
GO:0000780	condensed nuclear chromosome, centromeric region	7.15e-03	1.00e+00	7.124	1	1	7
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	7.15e-03	1.00e+00	7.124	1	2	7
GO:0051382	kinetochore assembly	7.15e-03	1.00e+00	7.124	1	2	7
GO:0016032	viral process	7.97e-03	1.00e+00	2.775	3	30	428
GO:0010944	negative regulation of transcription by competitive promoter binding	8.17e-03	1.00e+00	6.931	1	1	8
GO:0071354	cellular response to interleukin-6	9.18e-03	1.00e+00	6.762	1	1	9
GO:0005095	GTPase inhibitor activity	1.02e-02	1.00e+00	6.610	1	1	10
GO:0009416	response to light stimulus	1.02e-02	1.00e+00	6.610	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	1.12e-02	1.00e+00	6.472	1	4	11
GO:0006479	protein methylation	1.12e-02	1.00e+00	6.472	1	2	11
GO:0000132	establishment of mitotic spindle orientation	1.22e-02	1.00e+00	6.347	1	2	12
GO:0060749	mammary gland alveolus development	1.32e-02	1.00e+00	6.231	1	1	13
GO:0016597	amino acid binding	1.43e-02	1.00e+00	6.124	1	1	14
GO:0016575	histone deacetylation	1.43e-02	1.00e+00	6.124	1	2	14
GO:0000188	inactivation of MAPK activity	1.53e-02	1.00e+00	6.025	1	1	15
GO:0014003	oligodendrocyte development	1.53e-02	1.00e+00	6.025	1	1	15
GO:0008135	translation factor activity, nucleic acid binding	1.53e-02	1.00e+00	6.025	1	4	15
GO:0005743	mitochondrial inner membrane	1.64e-02	1.00e+00	3.309	2	9	197
GO:0005525	GTP binding	1.64e-02	1.00e+00	3.309	2	12	197
GO:0034080	CENP-A containing nucleosome assembly	2.03e-02	1.00e+00	5.610	1	2	20
GO:0071897	DNA biosynthetic process	2.03e-02	1.00e+00	5.610	1	2	20
GO:0030331	estrogen receptor binding	2.23e-02	1.00e+00	5.472	1	2	22
GO:0000049	tRNA binding	2.33e-02	1.00e+00	5.408	1	2	23
GO:0010827	regulation of glucose transport	2.53e-02	1.00e+00	5.288	1	7	25
GO:0008033	tRNA processing	2.53e-02	1.00e+00	5.288	1	2	25
GO:0005739	mitochondrion	2.57e-02	1.00e+00	2.152	3	32	659
GO:0005737	cytoplasm	2.85e-02	1.00e+00	1.154	6	127	2633
GO:0006418	tRNA aminoacylation for protein translation	2.93e-02	1.00e+00	5.073	1	4	29
GO:0009408	response to heat	3.13e-02	1.00e+00	4.977	1	1	31
GO:0007077	mitotic nuclear envelope disassembly	3.23e-02	1.00e+00	4.931	1	9	32
GO:0015030	Cajal body	3.23e-02	1.00e+00	4.931	1	3	32
GO:0000786	nucleosome	3.43e-02	1.00e+00	4.844	1	2	34
GO:0007254	JNK cascade	3.43e-02	1.00e+00	4.844	1	1	34
GO:0043434	response to peptide hormone	3.63e-02	1.00e+00	4.762	1	1	36
GO:0008645	hexose transport	3.63e-02	1.00e+00	4.762	1	8	36
GO:0003743	translation initiation factor activity	3.73e-02	1.00e+00	4.722	1	8	37
GO:0000278	mitotic cell cycle	3.91e-02	1.00e+00	2.637	2	28	314
GO:0045892	negative regulation of transcription, DNA-templated	3.98e-02	1.00e+00	2.623	2	17	317
GO:0000775	chromosome, centromeric region	4.12e-02	1.00e+00	4.574	1	6	41
GO:0005085	guanyl-nucleotide exchange factor activity	4.32e-02	1.00e+00	4.505	1	2	43
GO:0009749	response to glucose	4.52e-02	1.00e+00	4.440	1	1	45
GO:0051028	mRNA transport	4.71e-02	1.00e+00	4.377	1	5	47
GO:0015758	glucose transport	4.81e-02	1.00e+00	4.347	1	8	48
GO:0006334	nucleosome assembly	5.10e-02	1.00e+00	4.259	1	4	51
GO:0005643	nuclear pore	5.10e-02	1.00e+00	4.259	1	12	51
GO:0042826	histone deacetylase binding	5.79e-02	1.00e+00	4.073	1	5	58
GO:0006415	translational termination	6.27e-02	1.00e+00	3.954	1	2	63
GO:0006364	rRNA processing	6.66e-02	1.00e+00	3.865	1	2	67
GO:0030308	negative regulation of cell growth	6.94e-02	1.00e+00	3.802	1	3	70
GO:0016363	nuclear matrix	7.23e-02	1.00e+00	3.742	1	10	73
GO:0001649	osteoblast differentiation	7.33e-02	1.00e+00	3.722	1	5	74
GO:0015630	microtubule cytoskeleton	7.42e-02	1.00e+00	3.703	1	5	75
GO:0005634	nucleus	7.55e-02	1.00e+00	0.852	6	158	3246
GO:0005215	transporter activity	8.09e-02	1.00e+00	3.574	1	5	82
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	8.28e-02	1.00e+00	3.539	1	5	84
GO:0005829	cytosol	9.28e-02	1.00e+00	1.128	4	88	1787
GO:0006413	translational initiation	9.69e-02	1.00e+00	3.302	1	6	99
GO:0010467	gene expression	1.01e-01	1.00e+00	1.868	2	49	535
GO:0043547	positive regulation of GTPase activity	1.09e-01	1.00e+00	3.124	1	2	112
GO:0042981	regulation of apoptotic process	1.09e-01	1.00e+00	3.124	1	4	112
GO:0003924	GTPase activity	1.15e-01	1.00e+00	3.037	1	7	119
GO:0000082	G1/S transition of mitotic cell cycle	1.21e-01	1.00e+00	2.966	1	4	125
GO:0006184	GTP catabolic process	1.25e-01	1.00e+00	2.909	1	7	130
GO:0007165	signal transduction	1.28e-01	1.00e+00	1.660	2	24	618
GO:0005759	mitochondrial matrix	1.34e-01	1.00e+00	2.813	1	7	139
GO:0044212	transcription regulatory region DNA binding	1.37e-01	1.00e+00	2.772	1	13	143
GO:0005622	intracellular	1.39e-01	1.00e+00	2.752	1	2	145
GO:0001701	in utero embryonic development	1.47e-01	1.00e+00	2.665	1	7	154
GO:0007067	mitotic nuclear division	1.57e-01	1.00e+00	2.565	1	9	165
GO:0019221	cytokine-mediated signaling pathway	1.63e-01	1.00e+00	2.505	1	10	172
GO:0006412	translation	1.68e-01	1.00e+00	2.456	1	12	178
GO:0005975	carbohydrate metabolic process	1.75e-01	1.00e+00	2.392	1	10	186
GO:0015031	protein transport	1.90e-01	1.00e+00	2.266	1	10	203
GO:0043234	protein complex	1.95e-01	1.00e+00	2.217	1	13	210
GO:0044822	poly(A) RNA binding	1.95e-01	1.00e+00	1.289	2	45	799
GO:0019899	enzyme binding	1.95e-01	1.00e+00	2.217	1	7	210
GO:0005654	nucleoplasm	2.24e-01	1.00e+00	1.157	2	68	876
GO:0003682	chromatin binding	2.30e-01	1.00e+00	1.954	1	15	252
GO:0005524	ATP binding	2.31e-01	1.00e+00	1.131	2	37	892
GO:0046982	protein heterodimerization activity	2.41e-01	1.00e+00	1.882	1	11	265
GO:0008285	negative regulation of cell proliferation	2.50e-01	1.00e+00	1.818	1	11	277
GO:0055085	transmembrane transport	2.90e-01	1.00e+00	1.570	1	13	329
GO:0044267	cellular protein metabolic process	3.07e-01	1.00e+00	1.472	1	14	352
GO:0045893	positive regulation of transcription, DNA-templated	3.26e-01	1.00e+00	1.373	1	21	377
GO:0005730	nucleolus	3.60e-01	1.00e+00	0.682	2	74	1217
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.80e-01	1.00e+00	1.099	1	29	456
GO:0005887	integral component of plasma membrane	4.55e-01	1.00e+00	0.764	1	8	575
GO:0005576	extracellular region	5.05e-01	1.00e+00	0.559	1	15	663
GO:0070062	extracellular vesicular exosome	5.20e-01	1.00e+00	0.251	2	51	1641
GO:0006355	regulation of transcription, DNA-templated	5.33e-01	1.00e+00	0.450	1	31	715
GO:0044281	small molecule metabolic process	5.95e-01	1.00e+00	0.210	1	35	844
GO:0046872	metal ion binding	6.34e-01	1.00e+00	0.064	1	24	934
GO:0003677	DNA binding	6.40e-01	1.00e+00	0.044	1	52	947
GO:0006351	transcription, DNA-templated	6.89e-01	1.00e+00	-0.140	1	47	1076
GO:0016020	membrane	7.33e-01	1.00e+00	-0.306	1	56	1207
GO:0005886	plasma membrane	8.67e-01	1.00e+00	-0.869	1	46	1784

chia-Fav

reg-snw-4927

Statistics

Genes (10)

Interactions (11)

Related GO terms (118)