reg-snw-463

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.412	2.10e-08	1.10e-02	9.44e-03

chia-screen-data-Fav-reg-snw-463 subnetwork

Genes (6)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
NDUFA4L2	56901	44	-2.477	2.459	21	-	Yes	-
CPSF3	51692	43	-2.686	2.503	31	-	Yes	Yes
[ ZFHX3 ]	463	1	-1.296	2.412	38	TF	-	-
FOXM1	2305	9	-1.669	2.412	210	TF	-	-
TRAIP	10293	13	-2.546	2.454	30	TF	Yes	-
PRDM14	63978	7	-3.797	2.412	147	TF	Yes	Yes

Interactions (5)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
ZFHX3	463	FOXM1	2305	pd	<>	reg.ITFP.txt: no annot
ZFHX3	463	PRDM14	63978	pd	<	reg.pazar.txt: no annot
FOXM1	2305	TRAIP	10293	pd	<>	reg.ITFP.txt: no annot
FOXM1	2305	NDUFA4L2	56901	pd	>	reg.ITFP.txt: no annot
TRAIP	10293	CPSF3	51692	pd	>	reg.ITFP.txt: no annot

Related GO terms (82)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0034972	histone H3-R26 methylation	6.14e-04	1.00e+00	10.668	1	1	1
GO:0001827	inner cell mass cell fate commitment	6.14e-04	1.00e+00	10.668	1	1	1
GO:0006366	transcription from RNA polymerase II promoter	7.80e-04	1.00e+00	3.840	3	23	341
GO:2000781	positive regulation of double-strand break repair	1.23e-03	1.00e+00	9.668	1	1	2
GO:0044030	regulation of DNA methylation	2.46e-03	1.00e+00	8.668	1	1	4
GO:0071156	regulation of cell cycle arrest	2.46e-03	1.00e+00	8.668	1	2	4
GO:0030718	germ-line stem cell maintenance	2.46e-03	1.00e+00	8.668	1	1	4
GO:0004521	endoribonuclease activity	3.07e-03	1.00e+00	8.347	1	1	5
GO:0032873	negative regulation of stress-activated MAPK cascade	3.07e-03	1.00e+00	8.347	1	1	5
GO:0006398	histone mRNA 3'-end processing	3.07e-03	1.00e+00	8.347	1	1	5
GO:0044212	transcription regulatory region DNA binding	3.07e-03	1.00e+00	4.509	2	13	143
GO:0090344	negative regulation of cell aging	3.07e-03	1.00e+00	8.347	1	1	5
GO:0046578	regulation of Ras protein signal transduction	3.68e-03	1.00e+00	8.083	1	1	6
GO:0040037	negative regulation of fibroblast growth factor receptor signaling pathway	3.68e-03	1.00e+00	8.083	1	1	6
GO:0008409	5'-3' exonuclease activity	4.29e-03	1.00e+00	7.861	1	2	7
GO:0045662	negative regulation of myoblast differentiation	4.91e-03	1.00e+00	7.668	1	1	8
GO:0045663	positive regulation of myoblast differentiation	5.52e-03	1.00e+00	7.499	1	2	9
GO:0006379	mRNA cleavage	5.52e-03	1.00e+00	7.499	1	2	9
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	5.52e-03	1.00e+00	7.499	1	3	9
GO:0045664	regulation of neuron differentiation	6.13e-03	1.00e+00	7.347	1	1	10
GO:0040029	regulation of gene expression, epigenetic	6.13e-03	1.00e+00	7.347	1	1	10
GO:0006355	regulation of transcription, DNA-templated	6.61e-03	1.00e+00	2.772	3	31	715
GO:2000377	regulation of reactive oxygen species metabolic process	7.96e-03	1.00e+00	6.968	1	1	13
GO:0048873	homeostasis of number of cells within a tissue	8.57e-03	1.00e+00	6.861	1	2	14
GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	8.57e-03	1.00e+00	6.861	1	1	14
GO:0001708	cell fate specification	9.18e-03	1.00e+00	6.762	1	1	15
GO:0043565	sequence-specific DNA binding	1.10e-02	1.00e+00	3.565	2	8	275
GO:0009566	fertilization	1.10e-02	1.00e+00	6.499	1	1	18
GO:0006378	mRNA polyadenylation	1.10e-02	1.00e+00	6.499	1	3	18
GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic	1.28e-02	1.00e+00	6.276	1	2	21
GO:0007281	germ cell development	1.34e-02	1.00e+00	6.209	1	1	22
GO:0045892	negative regulation of transcription, DNA-templated	1.45e-02	1.00e+00	3.360	2	17	317
GO:0005057	receptor signaling protein activity	1.59e-02	1.00e+00	5.968	1	2	26
GO:0008168	methyltransferase activity	1.83e-02	1.00e+00	5.762	1	2	30
GO:0000902	cell morphogenesis	2.13e-02	1.00e+00	5.539	1	5	35
GO:0031124	mRNA 3'-end processing	2.13e-02	1.00e+00	5.539	1	4	35
GO:0006369	termination of RNA polymerase II transcription	2.31e-02	1.00e+00	5.421	1	5	38
GO:0006406	mRNA export from nucleus	2.67e-02	1.00e+00	5.209	1	7	44
GO:0001570	vasculogenesis	2.73e-02	1.00e+00	5.177	1	2	45
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	2.88e-02	1.00e+00	2.836	2	29	456
GO:0001558	regulation of cell growth	2.97e-02	1.00e+00	5.054	1	2	49
GO:0007517	muscle organ development	3.39e-02	1.00e+00	4.861	1	1	56
GO:0003705	RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity	3.51e-02	1.00e+00	4.810	1	3	58
GO:0001889	liver development	4.29e-02	1.00e+00	4.519	1	4	71
GO:0051726	regulation of cell cycle	4.40e-02	1.00e+00	4.479	1	3	73
GO:0003700	sequence-specific DNA binding transcription factor activity	4.53e-02	1.00e+00	2.484	2	22	582
GO:0042127	regulation of cell proliferation	4.82e-02	1.00e+00	4.347	1	4	80
GO:0030529	ribonucleoprotein complex	4.94e-02	1.00e+00	4.311	1	5	82
GO:0007050	cell cycle arrest	5.52e-02	1.00e+00	4.145	1	4	92
GO:0000086	G2/M transition of mitotic cell cycle	5.82e-02	1.00e+00	4.069	1	7	97
GO:0008270	zinc ion binding	6.79e-02	1.00e+00	2.163	2	39	727
GO:0007049	cell cycle	6.86e-02	1.00e+00	3.823	1	8	115
GO:0007420	brain development	7.09e-02	1.00e+00	3.774	1	3	119
GO:0000398	mRNA splicing, via spliceosome	7.61e-02	1.00e+00	3.668	1	15	128
GO:0016874	ligase activity	8.64e-02	1.00e+00	3.479	1	11	146
GO:0005667	transcription factor complex	8.70e-02	1.00e+00	3.469	1	8	147
GO:0005654	nucleoplasm	9.46e-02	1.00e+00	1.894	2	68	876
GO:0008380	RNA splicing	9.72e-02	1.00e+00	3.302	1	21	165
GO:0004842	ubiquitin-protein transferase activity	1.05e-01	1.00e+00	3.185	1	17	179
GO:0046872	metal ion binding	1.06e-01	1.00e+00	1.801	2	24	934
GO:0003677	DNA binding	1.08e-01	1.00e+00	1.781	2	52	947
GO:0016567	protein ubiquitination	1.10e-01	1.00e+00	3.114	1	14	188
GO:0035556	intracellular signal transduction	1.16e-01	1.00e+00	3.032	1	5	199
GO:0006281	DNA repair	1.18e-01	1.00e+00	3.003	1	24	203
GO:0019899	enzyme binding	1.22e-01	1.00e+00	2.954	1	7	210
GO:0019901	protein kinase binding	1.34e-01	1.00e+00	2.810	1	8	232
GO:0006351	transcription, DNA-templated	1.35e-01	1.00e+00	1.597	2	47	1076
GO:0008283	cell proliferation	1.38e-01	1.00e+00	2.768	1	8	239
GO:0003723	RNA binding	1.43e-01	1.00e+00	2.720	1	22	247
GO:0008284	positive regulation of cell proliferation	1.60e-01	1.00e+00	2.544	1	8	279
GO:0005730	nucleolus	1.66e-01	1.00e+00	1.419	2	74	1217
GO:0000278	mitotic cell cycle	1.78e-01	1.00e+00	2.374	1	28	314
GO:0048471	perinuclear region of cytoplasm	1.94e-01	1.00e+00	2.242	1	11	344
GO:0045893	positive regulation of transcription, DNA-templated	2.10e-01	1.00e+00	2.110	1	21	377
GO:0005515	protein binding	2.11e-01	1.00e+00	0.659	4	198	4124
GO:0006915	apoptotic process	2.27e-01	1.00e+00	1.985	1	15	411
GO:0010467	gene expression	2.87e-01	1.00e+00	1.605	1	49	535
GO:0005634	nucleus	3.18e-01	1.00e+00	0.589	3	158	3246
GO:0007165	signal transduction	3.25e-01	1.00e+00	1.397	1	24	618
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	3.36e-01	1.00e+00	1.338	1	29	644
GO:0005739	mitochondrion	3.43e-01	1.00e+00	1.304	1	32	659
GO:0005737	cytoplasm	8.48e-01	1.00e+00	-0.694	1	127	2633

chia-Fav

reg-snw-463

Statistics

Genes (6)

Interactions (5)

Related GO terms (82)