reg-snw-3735

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	2.341	5.17e-08	1.85e-02	1.50e-02

chia-screen-data-Fav-reg-snw-3735 subnetwork

Genes (8)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Transcription factor	Chia-Hits Primary	Chia-Hits Secondary
[ KARS ]	3735	12	-1.759	2.428	123	TF	-	-
CENPA	1058	27	-2.185	2.393	205	TF	Yes	-
PHB2	11331	17	-2.236	2.449	11	-	Yes	-
PHB	5245	82	-2.743	2.689	36	-	Yes	Yes
ACTR5	79913	4	-1.887	2.369	19	-	-	-
GSPT1	2935	32	-2.313	2.503	17	-	Yes	Yes
NOLC1	9221	15	-1.985	2.503	113	TF	-	-
GPS1	2873	86	-3.621	2.689	36	TF	Yes	Yes

Interactions (10)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
KARS	3735	NOLC1	9221	pd	<>	reg.ITFP.txt: no annot
KARS	3735	ACTR5	79913	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	NOLC1	9221	pd	<	reg.ITFP.txt: no annot
CENPA	1058	ACTR5	79913	pd	>	reg.ITFP.txt: no annot
GPS1	2873	PHB	5245	pd	>	reg.ITFP.txt: no annot
CENPA	1058	KARS	3735	pd	<>	reg.ITFP.txt: no annot
KARS	3735	PHB2	11331	pd	>	reg.ITFP.txt: no annot
KARS	3735	PHB	5245	pd	>	reg.ITFP.txt: no annot
GSPT1	2935	KARS	3735	pd	<	reg.ITFP.txt: no annot
GPS1	2873	PHB2	11331	pd	>	reg.ITFP.txt: no annot

Related GO terms (93)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0000939	condensed chromosome inner kinetochore	8.19e-04	1.00e+00	10.253	1	1	1
GO:0006430	lysyl-tRNA aminoacylation	8.19e-04	1.00e+00	10.253	1	1	1
GO:0004824	lysine-tRNA ligase activity	8.19e-04	1.00e+00	10.253	1	1	1
GO:0005515	protein binding	1.01e-03	1.00e+00	1.244	8	198	4124
GO:0015966	diadenosine tetraphosphate biosynthetic process	1.64e-03	1.00e+00	9.253	1	1	2
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	1.64e-03	1.00e+00	9.253	1	1	2
GO:0003747	translation release factor activity	1.64e-03	1.00e+00	9.253	1	2	2
GO:0000778	condensed nuclear chromosome kinetochore	2.46e-03	1.00e+00	8.668	1	2	3
GO:0071459	protein localization to chromosome, centromeric region	2.46e-03	1.00e+00	8.668	1	1	3
GO:0007000	nucleolus organization	3.27e-03	1.00e+00	8.253	1	1	4
GO:0060762	regulation of branching involved in mammary gland duct morphogenesis	3.27e-03	1.00e+00	8.253	1	1	4
GO:0007049	cell cycle	3.68e-03	1.00e+00	4.408	2	8	115
GO:0060744	mammary gland branching involved in thelarche	4.09e-03	1.00e+00	7.931	1	1	5
GO:2000323	negative regulation of glucocorticoid receptor signaling pathway	4.09e-03	1.00e+00	7.931	1	1	5
GO:0033600	negative regulation of mammary gland epithelial cell proliferation	4.09e-03	1.00e+00	7.931	1	1	5
GO:0050847	progesterone receptor signaling pathway	4.91e-03	1.00e+00	7.668	1	2	6
GO:0070914	UV-damage excision repair	4.91e-03	1.00e+00	7.668	1	1	6
GO:0000780	condensed nuclear chromosome, centromeric region	5.72e-03	1.00e+00	7.446	1	1	7
GO:0051382	kinetochore assembly	5.72e-03	1.00e+00	7.446	1	2	7
GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway	5.72e-03	1.00e+00	7.446	1	2	7
GO:0010944	negative regulation of transcription by competitive promoter binding	6.54e-03	1.00e+00	7.253	1	1	8
GO:0031011	Ino80 complex	6.54e-03	1.00e+00	7.253	1	3	8
GO:0010388	cullin deneddylation	6.54e-03	1.00e+00	7.253	1	4	8
GO:0071354	cellular response to interleukin-6	7.35e-03	1.00e+00	7.083	1	1	9
GO:0005095	GTPase inhibitor activity	8.17e-03	1.00e+00	6.931	1	1	10
GO:0060766	negative regulation of androgen receptor signaling pathway	8.98e-03	1.00e+00	6.794	1	4	11
GO:0006479	protein methylation	8.98e-03	1.00e+00	6.794	1	2	11
GO:0000132	establishment of mitotic spindle orientation	9.79e-03	1.00e+00	6.668	1	2	12
GO:0005743	mitochondrial inner membrane	1.05e-02	1.00e+00	3.631	2	9	197
GO:0005525	GTP binding	1.05e-02	1.00e+00	3.631	2	12	197
GO:0060749	mammary gland alveolus development	1.06e-02	1.00e+00	6.553	1	1	13
GO:0016597	amino acid binding	1.14e-02	1.00e+00	6.446	1	1	14
GO:0016575	histone deacetylation	1.14e-02	1.00e+00	6.446	1	2	14
GO:0000188	inactivation of MAPK activity	1.22e-02	1.00e+00	6.347	1	1	15
GO:0005739	mitochondrion	1.33e-02	1.00e+00	2.474	3	32	659
GO:0034080	CENP-A containing nucleosome assembly	1.63e-02	1.00e+00	5.931	1	2	20
GO:0071897	DNA biosynthetic process	1.63e-02	1.00e+00	5.931	1	2	20
GO:0030331	estrogen receptor binding	1.79e-02	1.00e+00	5.794	1	2	22
GO:0000049	tRNA binding	1.87e-02	1.00e+00	5.730	1	2	23
GO:0005634	nucleus	1.93e-02	1.00e+00	1.174	6	158	3246
GO:0008180	COP9 signalosome	1.95e-02	1.00e+00	5.668	1	6	24
GO:0008033	tRNA processing	2.03e-02	1.00e+00	5.610	1	2	25
GO:0006418	tRNA aminoacylation for protein translation	2.35e-02	1.00e+00	5.395	1	4	29
GO:0045892	negative regulation of transcription, DNA-templated	2.58e-02	1.00e+00	2.945	2	17	317
GO:0015030	Cajal body	2.59e-02	1.00e+00	5.253	1	3	32
GO:0000786	nucleosome	2.75e-02	1.00e+00	5.166	1	2	34
GO:0007254	JNK cascade	2.75e-02	1.00e+00	5.166	1	1	34
GO:0000775	chromosome, centromeric region	3.31e-02	1.00e+00	4.896	1	6	41
GO:0005737	cytoplasm	3.74e-02	1.00e+00	1.213	5	127	2633
GO:0006310	DNA recombination	4.03e-02	1.00e+00	4.610	1	8	50
GO:0006334	nucleosome assembly	4.10e-02	1.00e+00	4.581	1	4	51
GO:0006302	double-strand break repair	4.18e-02	1.00e+00	4.553	1	5	52
GO:0016032	viral process	4.50e-02	1.00e+00	2.512	2	30	428
GO:0042826	histone deacetylase binding	4.66e-02	1.00e+00	4.395	1	5	58
GO:0006415	translational termination	5.05e-02	1.00e+00	4.276	1	2	63
GO:0006364	rRNA processing	5.36e-02	1.00e+00	4.187	1	2	67
GO:0030308	negative regulation of cell growth	5.59e-02	1.00e+00	4.124	1	3	70
GO:0016363	nuclear matrix	5.83e-02	1.00e+00	4.064	1	10	73
GO:0001649	osteoblast differentiation	5.91e-02	1.00e+00	4.044	1	5	74
GO:0015630	microtubule cytoskeleton	5.98e-02	1.00e+00	4.025	1	5	75
GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	6.68e-02	1.00e+00	3.861	1	5	84
GO:0042981	regulation of apoptotic process	8.82e-02	1.00e+00	3.446	1	4	112
GO:0003924	GTPase activity	9.35e-02	1.00e+00	3.359	1	7	119
GO:0000082	G1/S transition of mitotic cell cycle	9.80e-02	1.00e+00	3.288	1	4	125
GO:0006184	GTP catabolic process	1.02e-01	1.00e+00	3.231	1	7	130
GO:0005759	mitochondrial matrix	1.08e-01	1.00e+00	3.134	1	7	139
GO:0044212	transcription regulatory region DNA binding	1.11e-01	1.00e+00	3.094	1	13	143
GO:0006355	regulation of transcription, DNA-templated	1.12e-01	1.00e+00	1.772	2	31	715
GO:0005622	intracellular	1.13e-01	1.00e+00	3.073	1	2	145
GO:0007067	mitotic nuclear division	1.27e-01	1.00e+00	2.887	1	9	165
GO:0044822	poly(A) RNA binding	1.35e-01	1.00e+00	1.611	2	45	799
GO:0005654	nucleoplasm	1.57e-01	1.00e+00	1.479	2	68	876
GO:0043234	protein complex	1.60e-01	1.00e+00	2.539	1	13	210
GO:0019899	enzyme binding	1.60e-01	1.00e+00	2.539	1	7	210
GO:0005524	ATP binding	1.61e-01	1.00e+00	1.453	2	37	892
GO:0003682	chromatin binding	1.89e-01	1.00e+00	2.276	1	15	252
GO:0046982	protein heterodimerization activity	1.98e-01	1.00e+00	2.204	1	11	265
GO:0008285	negative regulation of cell proliferation	2.06e-01	1.00e+00	2.140	1	11	277
GO:0006351	transcription, DNA-templated	2.18e-01	1.00e+00	1.182	2	47	1076
GO:0000278	mitotic cell cycle	2.30e-01	1.00e+00	1.959	1	28	314
GO:0045893	positive regulation of transcription, DNA-templated	2.70e-01	1.00e+00	1.695	1	21	377
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	3.18e-01	1.00e+00	1.421	1	29	456
GO:0010467	gene expression	3.63e-01	1.00e+00	1.190	1	49	535
GO:0005887	integral component of plasma membrane	3.85e-01	1.00e+00	1.086	1	8	575
GO:0070062	extracellular vesicular exosome	4.00e-01	1.00e+00	0.573	2	51	1641
GO:0007165	signal transduction	4.07e-01	1.00e+00	0.982	1	24	618
GO:0005576	extracellular region	4.30e-01	1.00e+00	0.881	1	15	663
GO:0005829	cytosol	4.46e-01	1.00e+00	0.450	2	88	1787
GO:0046872	metal ion binding	5.53e-01	1.00e+00	0.386	1	24	934
GO:0003677	DNA binding	5.58e-01	1.00e+00	0.366	1	52	947
GO:0016020	membrane	6.52e-01	1.00e+00	0.016	1	56	1207
GO:0005730	nucleolus	6.55e-01	1.00e+00	0.004	1	74	1217
GO:0005886	plasma membrane	8.01e-01	1.00e+00	-0.547	1	46	1784

chia-Fav

reg-snw-3735

Statistics

Genes (8)

Interactions (10)

Related GO terms (93)