int-snw-8971

Statistics

Dataset	Score	p-value 1	p-value 2	p-value 3
chia-screen-data-Fav	3.504	1.16e-23	1.57e-08	2.01e-06

chia-screen-data-Fav-int-snw-8971 subnetwork

Genes (5)

Gene Symbol	Entrez Gene ID	Frequency	chia-screen-data-Fav gene score	Best subnetwork score	Degree	Chia-Hits Primary	Chia-Hits Secondary
YAP1	10413	94	-4.256	3.538	53	Yes	-
POU5F1	5460	133	-5.148	3.538	179	Yes	Yes
HNRNPU	3192	76	-2.869	3.538	139	Yes	-
[ H1FX ]	8971	7	-2.421	3.504	35	Yes	Yes
DDIT3	1649	60	-2.825	3.504	343	Yes	Yes

Interactions (4)

Gene Symbol 1	Entrez Gene ID 1	Gene Symbol 2	Entrez Gene ID 2	Type	Direction	Origin databases / Sources
DDIT3	1649	HNRNPU	3192	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
DDIT3	1649	H1FX	8971	pp	--	int.I2D: BEHRENDS_AUTOPHAGY_LOW
HNRNPU	3192	POU5F1	5460	pp	--	int.I2D: BioGrid_Mouse, IntAct_Mouse
HNRNPU	3192	YAP1	10413	pp	--	int.I2D: HPRD; int.HPRD: in vitro, in vivo

Related GO terms (87)

Accession number	Name	Hypergeometric test	Corrected p-value	Enrichment ratio	Occurrence in subnetwork	Occurrences in all snw genes	Occurrences in all int/reg genes
GO:0042789	mRNA transcription from RNA polymerase II promoter	7.49e-06	1.08e-01	8.794	2	2	13
GO:0044212	transcription regulatory region DNA binding	1.53e-05	2.20e-01	5.687	3	17	168
GO:0005654	nucleoplasm	1.48e-04	1.00e+00	3.415	4	64	1082
GO:0003677	DNA binding	2.36e-04	1.00e+00	3.244	4	49	1218
GO:0060795	cell fate commitment involved in formation of primary germ layer	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090308	regulation of methylation-dependent chromatin silencing	3.47e-04	1.00e+00	11.494	1	1	1
GO:0090081	regulation of heart induction by regulation of canonical Wnt signaling pathway	3.47e-04	1.00e+00	11.494	1	1	1
GO:2000016	negative regulation of determination of dorsal identity	3.47e-04	1.00e+00	11.494	1	1	1
GO:0060965	negative regulation of gene silencing by miRNA	3.47e-04	1.00e+00	11.494	1	1	1
GO:0009786	regulation of asymmetric cell division	6.93e-04	1.00e+00	10.494	1	1	2
GO:0060242	contact inhibition	6.93e-04	1.00e+00	10.494	1	1	2
GO:0044324	regulation of transcription involved in anterior/posterior axis specification	6.93e-04	1.00e+00	10.494	1	1	2
GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	6.93e-04	1.00e+00	10.494	1	1	2
GO:0060913	cardiac cell fate determination	1.04e-03	1.00e+00	9.909	1	1	3
GO:0003130	BMP signaling pathway involved in heart induction	1.04e-03	1.00e+00	9.909	1	1	3
GO:0006974	cellular response to DNA damage stimulus	1.07e-03	1.00e+00	5.256	2	7	151
GO:0003714	transcription corepressor activity	1.48e-03	1.00e+00	5.018	2	11	178
GO:0001714	endodermal cell fate specification	1.73e-03	1.00e+00	9.172	1	1	5
GO:0043620	regulation of DNA-templated transcription in response to stress	1.73e-03	1.00e+00	9.172	1	1	5
GO:0070934	CRD-mediated mRNA stabilization	1.73e-03	1.00e+00	9.172	1	2	5
GO:0070937	CRD-mediated mRNA stability complex	2.08e-03	1.00e+00	8.909	1	3	6
GO:0008134	transcription factor binding	2.71e-03	1.00e+00	4.575	2	18	242
GO:0001955	blood vessel maturation	2.77e-03	1.00e+00	8.494	1	1	8
GO:0006355	regulation of transcription, DNA-templated	2.96e-03	1.00e+00	3.118	3	43	997
GO:0006983	ER overload response	3.12e-03	1.00e+00	8.324	1	1	9
GO:0005634	nucleus	3.15e-03	1.00e+00	1.662	5	159	4559
GO:0035413	positive regulation of catenin import into nucleus	3.46e-03	1.00e+00	8.172	1	2	10
GO:0044822	poly(A) RNA binding	3.50e-03	1.00e+00	3.035	3	50	1056
GO:0045662	negative regulation of myoblast differentiation	3.81e-03	1.00e+00	8.035	1	3	11
GO:0060391	positive regulation of SMAD protein import into nucleus	3.81e-03	1.00e+00	8.035	1	4	11
GO:0035198	miRNA binding	4.15e-03	1.00e+00	7.909	1	1	12
GO:0071480	cellular response to gamma radiation	4.50e-03	1.00e+00	7.794	1	1	13
GO:0001824	blastocyst development	5.19e-03	1.00e+00	7.587	1	2	15
GO:0043565	sequence-specific DNA binding	5.47e-03	1.00e+00	4.060	2	11	346
GO:0032757	positive regulation of interleukin-8 production	6.92e-03	1.00e+00	7.172	1	1	20
GO:0036464	cytoplasmic ribonucleoprotein granule	7.60e-03	1.00e+00	7.035	1	2	22
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	7.95e-03	1.00e+00	6.971	1	1	23
GO:0035329	hippo signaling	8.98e-03	1.00e+00	6.794	1	5	26
GO:0051209	release of sequestered calcium ion into cytosol	8.98e-03	1.00e+00	6.794	1	1	26
GO:0042594	response to starvation	1.07e-02	1.00e+00	6.540	1	4	31
GO:1903507	negative regulation of nucleic acid-templated transcription	1.10e-02	1.00e+00	6.494	1	2	32
GO:0035019	somatic stem cell maintenance	1.38e-02	1.00e+00	6.172	1	6	40
GO:0043525	positive regulation of neuron apoptotic process	1.58e-02	1.00e+00	5.971	1	4	46
GO:0006986	response to unfolded protein	1.72e-02	1.00e+00	5.850	1	4	50
GO:0034976	response to endoplasmic reticulum stress	1.76e-02	1.00e+00	5.822	1	2	51
GO:0045454	cell redox homeostasis	1.76e-02	1.00e+00	5.822	1	1	51
GO:0009611	response to wounding	1.79e-02	1.00e+00	5.794	1	5	52
GO:0010467	gene expression	1.96e-02	1.00e+00	3.108	2	45	669
GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity	2.03e-02	1.00e+00	5.612	1	6	59
GO:0006396	RNA processing	2.03e-02	1.00e+00	5.612	1	5	59
GO:0000786	nucleosome	2.03e-02	1.00e+00	5.612	1	2	59
GO:0006987	activation of signaling protein activity involved in unfolded protein response	2.10e-02	1.00e+00	5.563	1	2	61
GO:0003700	sequence-specific DNA binding transcription factor activity	2.13e-02	1.00e+00	3.045	2	39	699
GO:0010468	regulation of gene expression	2.34e-02	1.00e+00	5.407	1	2	68
GO:0006334	nucleosome assembly	2.47e-02	1.00e+00	5.324	1	3	72
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	2.54e-02	1.00e+00	5.285	1	4	74
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	2.57e-02	1.00e+00	5.265	1	1	75
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	2.68e-02	1.00e+00	2.870	2	41	789
GO:0071013	catalytic step 2 spliceosome	2.68e-02	1.00e+00	5.209	1	7	78
GO:0030968	endoplasmic reticulum unfolded protein response	2.71e-02	1.00e+00	5.190	1	2	79
GO:0009653	anatomical structure morphogenesis	2.84e-02	1.00e+00	5.119	1	2	83
GO:0090090	negative regulation of canonical Wnt signaling pathway	2.95e-02	1.00e+00	5.068	1	8	86
GO:0001649	osteoblast differentiation	3.15e-02	1.00e+00	4.971	1	5	92
GO:0005770	late endosome	3.18e-02	1.00e+00	4.955	1	2	93
GO:0030529	ribonucleoprotein complex	3.82e-02	1.00e+00	4.687	1	5	112
GO:0005829	cytosol	3.93e-02	1.00e+00	1.794	3	86	2496
GO:0007050	cell cycle arrest	4.23e-02	1.00e+00	4.540	1	5	124
GO:0016055	Wnt signaling pathway	4.69e-02	1.00e+00	4.386	1	4	138
GO:0000398	mRNA splicing, via spliceosome	5.56e-02	1.00e+00	4.137	1	15	164
GO:0005667	transcription factor complex	5.92e-02	1.00e+00	4.043	1	17	175
GO:0031625	ubiquitin protein ligase binding	6.02e-02	1.00e+00	4.018	1	5	178
GO:0006367	transcription initiation from RNA polymerase II promoter	6.22e-02	1.00e+00	3.971	1	22	184
GO:0008380	RNA splicing	7.66e-02	1.00e+00	3.661	1	22	228
GO:0003713	transcription coactivator activity	7.95e-02	1.00e+00	3.605	1	24	237
GO:0005515	protein binding	1.01e-01	1.00e+00	0.938	4	198	6024
GO:0008283	cell proliferation	1.09e-01	1.00e+00	3.137	1	14	328
GO:0003723	RNA binding	1.13e-01	1.00e+00	3.076	1	18	342
GO:0046982	protein heterodimerization activity	1.25e-01	1.00e+00	2.924	1	8	380
GO:0009986	cell surface	1.32e-01	1.00e+00	2.843	1	9	402
GO:0045892	negative regulation of transcription, DNA-templated	1.35e-01	1.00e+00	2.804	1	24	413
GO:0006366	transcription from RNA polymerase II promoter	1.37e-01	1.00e+00	2.783	1	30	419
GO:0044267	cellular protein metabolic process	1.54e-01	1.00e+00	2.605	1	20	474
GO:0045893	positive regulation of transcription, DNA-templated	1.55e-01	1.00e+00	2.593	1	24	478
GO:0005524	ATP binding	3.76e-01	1.00e+00	1.152	1	31	1298
GO:0005737	cytoplasm	3.91e-01	1.00e+00	0.615	2	124	3767
GO:0005730	nucleolus	4.53e-01	1.00e+00	0.814	1	66	1641
GO:0016020	membrane	4.62e-01	1.00e+00	0.779	1	46	1681

chia-Fav

int-snw-8971

Statistics

Genes (5)

Interactions (4)

Related GO terms (87)